Lagenaria siceraria endornavirus-Hubei
Average proteome isoelectric point is 6.03
Get precalculated fractions of proteins
Acidic
pI < 6.8
6.8-7.4
pI > 7.4
Basic
All
Note: above files contain also dissociation constants (pKa)
Virtual 2D-PAGE plot for 1 proteins (isoelectric point calculated using IPC2_protein)
Get csv file with sequences according to given criteria:
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Summary statistics related to proteome-wise predictions
Protein with the lowest isoelectric point:
>tr|A0A1S7D814|A0A1S7D814_9VIRU Polyprotein OS=Lagenaria siceraria endornavirus-Hubei OX=1965306 PE=4 SV=1
MM1 pKa = 7.38 QMNTDD6 pKa = 4.51 AITPYY11 pKa = 9.76 KK12 pKa = 10.11 RR13 pKa = 11.84 KK14 pKa = 10.58 YY15 pKa = 9.08 KK16 pKa = 10.49 DD17 pKa = 3.0 KK18 pKa = 10.68 PLRR21 pKa = 11.84 LLNKK25 pKa = 9.4 EE26 pKa = 4.29 FSNHH30 pKa = 3.85 LQGWIKK36 pKa = 10.61 LPRR39 pKa = 11.84 NQSVTINKK47 pKa = 9.14 NPWIKK52 pKa = 10.65 SFQKK56 pKa = 10.36 LFKK59 pKa = 10.38 DD60 pKa = 3.3 KK61 pKa = 10.85 RR62 pKa = 11.84 EE63 pKa = 4.38 HH64 pKa = 7.45 IFDD67 pKa = 3.8 NNKK70 pKa = 10.21 LKK72 pKa = 10.68 LVPAIRR78 pKa = 11.84 GEE80 pKa = 4.0 RR81 pKa = 11.84 KK82 pKa = 9.47 IRR84 pKa = 11.84 DD85 pKa = 3.73 TVGTVATNVTYY96 pKa = 10.73 DD97 pKa = 3.67 DD98 pKa = 4.13 GLGNVINFNEE108 pKa = 4.56 LHH110 pKa = 6.51 PMDD113 pKa = 4.17 VVKK116 pKa = 10.56 ILYY119 pKa = 9.24 NVNCLGIEE127 pKa = 4.1 LWKK130 pKa = 10.43 SDD132 pKa = 3.77 YY133 pKa = 10.06 YY134 pKa = 10.87 TIQDD138 pKa = 3.87 YY139 pKa = 10.75 IDD141 pKa = 3.72 KK142 pKa = 10.53 VKK144 pKa = 10.62 HH145 pKa = 6.29 LEE147 pKa = 4.25 LDD149 pKa = 3.68 DD150 pKa = 4.9 DD151 pKa = 4.63 EE152 pKa = 6.86 KK153 pKa = 11.64 DD154 pKa = 3.63 EE155 pKa = 5.35 EE156 pKa = 4.73 DD157 pKa = 5.9 FLDD160 pKa = 5.69 EE161 pKa = 6.81 DD162 pKa = 5.06 DD163 pKa = 6.36 LDD165 pKa = 4.47 DD166 pKa = 4.61 KK167 pKa = 11.63 LIIKK171 pKa = 7.56 MVKK174 pKa = 9.31 PGRR177 pKa = 11.84 GNCTSEE183 pKa = 4.21 ILLALDD189 pKa = 4.88 KK190 pKa = 10.64 ILKK193 pKa = 10.08 RR194 pKa = 11.84 FGGFEE199 pKa = 3.8 GYY201 pKa = 10.89 YY202 pKa = 10.51 NYY204 pKa = 10.5 FLEE207 pKa = 4.08 NHH209 pKa = 6.51 FKK211 pKa = 10.67 HH212 pKa = 6.57 FGYY215 pKa = 10.49 LEE217 pKa = 4.42 CVDD220 pKa = 3.93 GSYY223 pKa = 11.12 DD224 pKa = 3.43 FHH226 pKa = 8.03 SVKK229 pKa = 10.41 FNPLKK234 pKa = 10.46 VCGVCGRR241 pKa = 11.84 VNHH244 pKa = 5.86 YY245 pKa = 10.61 NQFNRR250 pKa = 11.84 GLRR253 pKa = 11.84 QVHH256 pKa = 5.79 YY257 pKa = 10.33 SLSHH261 pKa = 5.48 YY262 pKa = 8.74 KK263 pKa = 10.14 QKK265 pKa = 11.1 SKK267 pKa = 10.92 AIKK270 pKa = 10.03 EE271 pKa = 4.21 DD272 pKa = 3.56 FLTEE276 pKa = 3.8 FDD278 pKa = 3.85 EE279 pKa = 4.45 HH280 pKa = 6.8 HH281 pKa = 7.02 KK282 pKa = 8.76 PTNIPWRR289 pKa = 11.84 CGYY292 pKa = 10.24 CFSDD296 pKa = 3.56 LNYY299 pKa = 10.25 VVLIEE304 pKa = 4.38 KK305 pKa = 10.78 YY306 pKa = 10.08 MMVKK310 pKa = 10.43 LIEE313 pKa = 4.29 YY314 pKa = 8.79 VCNHH318 pKa = 6.42 LFVLQGDD325 pKa = 4.24 IEE327 pKa = 4.35 QLMKK331 pKa = 10.2 IGYY334 pKa = 9.45 GDD336 pKa = 3.34 IYY338 pKa = 11.0 EE339 pKa = 5.02 DD340 pKa = 5.11 LDD342 pKa = 3.86 IKK344 pKa = 11.07 DD345 pKa = 3.58 KK346 pKa = 11.16 EE347 pKa = 4.44 AIKK350 pKa = 10.69 SHH352 pKa = 7.09 DD353 pKa = 3.98 EE354 pKa = 3.89 IVVNNYY360 pKa = 9.5 FYY362 pKa = 10.85 HH363 pKa = 5.25 SQRR366 pKa = 11.84 KK367 pKa = 8.33 IVTVGQDD374 pKa = 2.73 FDD376 pKa = 4.13 AASHH380 pKa = 6.03 RR381 pKa = 11.84 VINDD385 pKa = 3.18 VLGGCYY391 pKa = 9.45 FRR393 pKa = 11.84 PTSKK397 pKa = 10.69 LNSIKK402 pKa = 10.59 PEE404 pKa = 4.81 FIAEE408 pKa = 4.45 LSTFSEE414 pKa = 4.45 IIEE417 pKa = 4.17 RR418 pKa = 11.84 TLVGRR423 pKa = 11.84 DD424 pKa = 3.43 IVCLGNVLPGTNRR437 pKa = 11.84 TNVHH441 pKa = 5.06 NWYY444 pKa = 10.34 HH445 pKa = 4.99 NQTWFSKK452 pKa = 10.51 DD453 pKa = 3.45 PEE455 pKa = 4.65 VMCSSKK461 pKa = 10.79 GICGHH466 pKa = 5.7 NKK468 pKa = 9.98 NYY470 pKa = 9.82 FVYY473 pKa = 10.62 GNVGMMGQPLNNILNIVEE491 pKa = 4.32 GQRR494 pKa = 11.84 ALQFITPIMTATRR507 pKa = 11.84 TLPDD511 pKa = 3.42 STGMFQRR518 pKa = 11.84 TEE520 pKa = 4.18 DD521 pKa = 3.65 NLNFYY526 pKa = 10.98 LDD528 pKa = 4.11 GNPVPINFMTDD539 pKa = 2.41 TYY541 pKa = 11.53 NALNNYY547 pKa = 9.31 QIIKK551 pKa = 9.06 WDD553 pKa = 3.31 RR554 pKa = 11.84 KK555 pKa = 8.63 LFYY558 pKa = 10.69 VVEE561 pKa = 4.36 VKK563 pKa = 10.55 KK564 pKa = 11.26 LNLTRR569 pKa = 11.84 LMTIVGPFNDD579 pKa = 4.3 TIDD582 pKa = 3.87 YY583 pKa = 8.26 PRR585 pKa = 11.84 LMVDD589 pKa = 3.07 NEE591 pKa = 4.05 RR592 pKa = 11.84 GIKK595 pKa = 9.46 IRR597 pKa = 11.84 IRR599 pKa = 11.84 LPDD602 pKa = 3.56 IDD604 pKa = 4.72 SFMGKK609 pKa = 7.75 TKK611 pKa = 10.49 GLNYY615 pKa = 9.75 QPKK618 pKa = 8.52 TFEE621 pKa = 4.51 LNVNLFRR628 pKa = 11.84 YY629 pKa = 10.28 LCMRR633 pKa = 11.84 NLNRR637 pKa = 11.84 KK638 pKa = 8.64 VSHH641 pKa = 5.56 EE642 pKa = 4.05 TLRR645 pKa = 11.84 PYY647 pKa = 11.1 AVGFSMRR654 pKa = 11.84 RR655 pKa = 11.84 FVVHH659 pKa = 6.48 NKK661 pKa = 9.71 VISNPTIAYY670 pKa = 7.63 EE671 pKa = 4.28 DD672 pKa = 4.32 LDD674 pKa = 3.4 MHH676 pKa = 6.89 IILSRR681 pKa = 11.84 VCMMKK686 pKa = 10.54 LKK688 pKa = 10.33 NCFEE692 pKa = 4.1 ISHH695 pKa = 6.51 NYY697 pKa = 9.49 SKK699 pKa = 11.09 ALKK702 pKa = 10.17 LLGPFRR708 pKa = 11.84 SMVGDD713 pKa = 3.63 MEE715 pKa = 4.65 SALTASMIGLIGEE728 pKa = 4.2 ILEE731 pKa = 4.31 NTLGLKK737 pKa = 9.15 WDD739 pKa = 4.3 AVLSMLDD746 pKa = 3.55 GARR749 pKa = 11.84 LQSMLMGVGKK759 pKa = 10.49 EE760 pKa = 4.25 DD761 pKa = 3.33 FWEE764 pKa = 4.38 HH765 pKa = 7.02 LLQLTEE771 pKa = 4.93 NITTVPPKK779 pKa = 9.97 ILDD782 pKa = 3.72 MEE784 pKa = 4.35 RR785 pKa = 11.84 HH786 pKa = 4.9 TEE788 pKa = 3.99 EE789 pKa = 4.98 EE790 pKa = 3.82 ITFALQNCMHH800 pKa = 6.92 HH801 pKa = 7.16 SIEE804 pKa = 4.49 CNHH807 pKa = 5.43 VRR809 pKa = 11.84 VKK811 pKa = 10.98 ADD813 pKa = 4.18 NRR815 pKa = 11.84 CCCCNLPITDD825 pKa = 4.26 EE826 pKa = 4.22 LFCNVVNPNPVSNEE840 pKa = 3.72 PYY842 pKa = 7.98 FTPNVYY848 pKa = 9.75 EE849 pKa = 4.08 VEE851 pKa = 4.3 PEE853 pKa = 4.03 RR854 pKa = 11.84 EE855 pKa = 3.91 EE856 pKa = 3.88 QQIGNIEE863 pKa = 3.87 KK864 pKa = 10.84 DD865 pKa = 3.52 KK866 pKa = 11.32 IVDD869 pKa = 3.54 NLANRR874 pKa = 11.84 IMLAMRR880 pKa = 11.84 DD881 pKa = 3.33 TSIRR885 pKa = 11.84 DD886 pKa = 3.11 RR887 pKa = 11.84 RR888 pKa = 11.84 VQPKK892 pKa = 10.39 GPYY895 pKa = 9.45 KK896 pKa = 10.67 LPLEE900 pKa = 4.25 QPPVTKK906 pKa = 9.67 ITPDD910 pKa = 3.05 NARR913 pKa = 11.84 ITEE916 pKa = 4.07 KK917 pKa = 11.27 ANVEE921 pKa = 4.0 EE922 pKa = 4.66 SKK924 pKa = 9.37 PTVDD928 pKa = 4.19 IKK930 pKa = 9.73 VTKK933 pKa = 10.51 SKK935 pKa = 9.93 TSSFKK940 pKa = 11.13 SKK942 pKa = 9.32 TSSIGEE948 pKa = 4.04 PPQNAEE954 pKa = 3.32 GWQKK958 pKa = 9.85 VLRR961 pKa = 11.84 RR962 pKa = 11.84 GKK964 pKa = 10.08 EE965 pKa = 3.77 KK966 pKa = 9.52 PTDD969 pKa = 3.29 IANAILDD976 pKa = 4.25 NIMEE980 pKa = 4.37 NAEE983 pKa = 4.27 RR984 pKa = 11.84 LTISTDD990 pKa = 2.99 NVEE993 pKa = 4.99 AINMLGYY1000 pKa = 10.8 DD1001 pKa = 4.37 FVRR1004 pKa = 11.84 HH1005 pKa = 5.64 CCEE1008 pKa = 3.55 TVQYY1012 pKa = 11.16 EE1013 pKa = 4.04 NDD1015 pKa = 3.52 LNNGVNEE1022 pKa = 4.5 IYY1024 pKa = 10.6 YY1025 pKa = 10.33 LPHH1028 pKa = 7.11 LPTGSLILPRR1038 pKa = 11.84 DD1039 pKa = 3.42 SFEE1042 pKa = 6.07 IIDD1045 pKa = 4.11 KK1046 pKa = 10.92 VYY1048 pKa = 10.51 IPNSGPLTCAFDD1060 pKa = 4.46 AYY1062 pKa = 10.6 HH1063 pKa = 6.91 FSTEE1067 pKa = 4.05 PGSLQEE1073 pKa = 4.62 MIDD1076 pKa = 3.35 IVGAQPPFSTEE1087 pKa = 3.77 HH1088 pKa = 6.22 LSLYY1092 pKa = 10.68 AKK1094 pKa = 8.87 WRR1096 pKa = 11.84 KK1097 pKa = 9.52 DD1098 pKa = 3.33 NIMILDD1104 pKa = 4.36 DD1105 pKa = 3.62 NHH1107 pKa = 6.3 VHH1109 pKa = 5.53 VEE1111 pKa = 3.87 KK1112 pKa = 10.9 HH1113 pKa = 5.68 NEE1115 pKa = 3.88 SSNTFAVIQFEE1126 pKa = 4.24 HH1127 pKa = 7.06 GEE1129 pKa = 4.15 TNADD1133 pKa = 2.97 IGHH1136 pKa = 7.03 FLPVTIKK1143 pKa = 10.28 RR1144 pKa = 11.84 VKK1146 pKa = 8.15 PTPIYY1151 pKa = 10.18 FYY1153 pKa = 10.8 HH1154 pKa = 7.43 RR1155 pKa = 11.84 DD1156 pKa = 3.24 PNAIVEE1162 pKa = 4.16 RR1163 pKa = 11.84 DD1164 pKa = 3.63 HH1165 pKa = 7.35 IVKK1168 pKa = 9.89 NRR1170 pKa = 11.84 YY1171 pKa = 8.72 GKK1173 pKa = 9.7 MYY1175 pKa = 10.66 SSTCLPTWSPKK1186 pKa = 10.83 DD1187 pKa = 3.57 NLSCEE1192 pKa = 3.98 ITYY1195 pKa = 10.78 HH1196 pKa = 6.55 NITVDD1201 pKa = 3.39 VRR1203 pKa = 11.84 VSEE1206 pKa = 4.59 AIKK1209 pKa = 9.94 PLKK1212 pKa = 10.21 LEE1214 pKa = 4.44 KK1215 pKa = 10.1 IEE1217 pKa = 4.11 NEE1219 pKa = 3.71 WYY1221 pKa = 8.39 LTNNLEE1227 pKa = 4.36 TRR1229 pKa = 11.84 LHH1231 pKa = 6.83 LIDD1234 pKa = 4.75 KK1235 pKa = 9.64 EE1236 pKa = 4.26 KK1237 pKa = 10.58 IHH1239 pKa = 6.97 AKK1241 pKa = 9.68 LPKK1244 pKa = 9.81 IFEE1247 pKa = 4.37 KK1248 pKa = 10.84 YY1249 pKa = 9.12 ISKK1252 pKa = 10.08 IEE1254 pKa = 3.91 YY1255 pKa = 10.37 GLALKK1260 pKa = 10.6 LPSNEE1265 pKa = 3.49 IEE1267 pKa = 4.39 EE1268 pKa = 4.14 YY1269 pKa = 10.36 RR1270 pKa = 11.84 HH1271 pKa = 6.09 IDD1273 pKa = 3.05 KK1274 pKa = 10.42 EE1275 pKa = 4.39 LPVNYY1280 pKa = 8.0 EE1281 pKa = 4.03 TEE1283 pKa = 4.22 LEE1285 pKa = 4.18 AEE1287 pKa = 4.23 LLEE1290 pKa = 4.07 ILRR1293 pKa = 11.84 VFARR1297 pKa = 11.84 LSEE1300 pKa = 4.26 LAGQVPFRR1308 pKa = 11.84 DD1309 pKa = 3.21 IKK1311 pKa = 9.83 QTHH1314 pKa = 5.7 QGHH1317 pKa = 5.99 ISSWFGKK1324 pKa = 10.21 SKK1326 pKa = 10.64 FSIPGGKK1333 pKa = 4.71 THH1335 pKa = 6.87 KK1336 pKa = 8.75 MKK1338 pKa = 11.01 KK1339 pKa = 8.66 MDD1341 pKa = 3.49 VVMLKK1346 pKa = 9.78 IQGKK1350 pKa = 7.28 WIKK1353 pKa = 9.26 STIVGFDD1360 pKa = 3.23 RR1361 pKa = 11.84 NNPVLDD1367 pKa = 3.69 YY1368 pKa = 11.33 VAVCEE1373 pKa = 4.19 QRR1375 pKa = 11.84 ASLVEE1380 pKa = 4.28 LKK1382 pKa = 10.62 EE1383 pKa = 4.35 SMGSQIRR1390 pKa = 11.84 EE1391 pKa = 4.08 LVGLCQSYY1399 pKa = 11.41 VDD1401 pKa = 5.06 LKK1403 pKa = 9.57 TLKK1406 pKa = 10.72 SKK1408 pKa = 10.55 LAEE1411 pKa = 4.3 AKK1413 pKa = 10.35 FLTGPAGFGKK1423 pKa = 8.27 STKK1426 pKa = 9.38 IGQSAVPGDD1435 pKa = 4.03 LCVAMTTSAVKK1446 pKa = 10.31 ALQEE1450 pKa = 3.98 KK1451 pKa = 7.36 VTRR1454 pKa = 11.84 GVKK1457 pKa = 10.36 VMTLEE1462 pKa = 4.02 RR1463 pKa = 11.84 ALYY1466 pKa = 9.49 SHH1468 pKa = 7.25 AKK1470 pKa = 8.42 TGQTLFVDD1478 pKa = 4.53 EE1479 pKa = 4.32 ATMVNWLFLGHH1490 pKa = 7.76 LITDD1494 pKa = 3.48 QSRR1497 pKa = 11.84 IEE1499 pKa = 4.2 LFGAEE1504 pKa = 3.99 NQIGKK1509 pKa = 9.62 RR1510 pKa = 11.84 DD1511 pKa = 3.62 MSKK1514 pKa = 9.14 TPGIRR1519 pKa = 11.84 YY1520 pKa = 9.53 NITLSDD1526 pKa = 3.71 FVKK1529 pKa = 10.48 PEE1531 pKa = 3.82 NKK1533 pKa = 8.47 ITEE1536 pKa = 3.99 HH1537 pKa = 4.53 HH1538 pKa = 6.71 TYY1540 pKa = 10.59 RR1541 pKa = 11.84 IGEE1544 pKa = 4.19 PLVTLLRR1551 pKa = 11.84 SVEE1554 pKa = 4.1 PKK1556 pKa = 10.92 LMTKK1560 pKa = 10.51 ASHH1563 pKa = 5.71 KK1564 pKa = 6.03 TTYY1567 pKa = 9.91 TITVLDD1573 pKa = 3.86 PAMVEE1578 pKa = 4.08 NINNIVKK1585 pKa = 10.02 DD1586 pKa = 4.08 RR1587 pKa = 11.84 KK1588 pKa = 9.64 PEE1590 pKa = 4.1 VIITPYY1596 pKa = 10.37 SYY1598 pKa = 11.22 NRR1600 pKa = 11.84 NLIEE1604 pKa = 4.08 QFLKK1608 pKa = 10.55 HH1609 pKa = 5.68 EE1610 pKa = 4.37 RR1611 pKa = 11.84 VPVVTTHH1618 pKa = 7.28 AYY1620 pKa = 9.72 QGVEE1624 pKa = 4.06 VSRR1627 pKa = 11.84 SMVVLKK1633 pKa = 10.8 ADD1635 pKa = 3.81 AGNRR1639 pKa = 11.84 WDD1641 pKa = 4.78 LNGHH1645 pKa = 5.79 PEE1647 pKa = 4.13 YY1648 pKa = 11.04 LNSALTRR1655 pKa = 11.84 AKK1657 pKa = 9.96 YY1658 pKa = 10.11 HH1659 pKa = 5.98 VDD1661 pKa = 3.31 IIIYY1665 pKa = 10.51 GNYY1668 pKa = 9.06 TDD1670 pKa = 4.47 VKK1672 pKa = 9.7 SLEE1675 pKa = 5.04 DD1676 pKa = 3.18 IMTQVGGMDD1685 pKa = 3.78 YY1686 pKa = 10.98 EE1687 pKa = 4.09 YY1688 pKa = 10.95 LQYY1691 pKa = 10.79 FNEE1694 pKa = 4.62 NIEE1697 pKa = 4.3 SATTEE1702 pKa = 3.77 IAEE1705 pKa = 4.28 VNQSNEE1711 pKa = 4.03 TNKK1714 pKa = 10.35 GDD1716 pKa = 4.27 KK1717 pKa = 9.62 LTLKK1721 pKa = 9.81 TGTALPDD1728 pKa = 3.59 VITINTMHH1736 pKa = 6.94 EE1737 pKa = 4.13 LSEE1740 pKa = 4.25 EE1741 pKa = 4.11 MVNQLNEE1748 pKa = 4.48 LNISMQGAKK1757 pKa = 8.62 LTYY1760 pKa = 9.57 QKK1762 pKa = 10.67 LHH1764 pKa = 6.88 EE1765 pKa = 4.77 GTSVTTQFAGATVSKK1780 pKa = 8.95 VTNINGIVNVDD1791 pKa = 3.7 ANPIIKK1797 pKa = 10.19 SKK1799 pKa = 10.49 IMQNLDD1805 pKa = 3.28 TPIDD1809 pKa = 3.7 VPEE1812 pKa = 4.85 LIKK1815 pKa = 10.8 EE1816 pKa = 4.17 QVDD1819 pKa = 3.86 GKK1821 pKa = 10.32 SQSIEE1826 pKa = 3.85 CKK1828 pKa = 7.72 MTLRR1832 pKa = 11.84 QTNKK1836 pKa = 9.11 IRR1838 pKa = 11.84 EE1839 pKa = 4.4 LTWILDD1845 pKa = 3.5 KK1846 pKa = 11.27 TIDD1849 pKa = 4.11 RR1850 pKa = 11.84 EE1851 pKa = 4.46 LKK1853 pKa = 9.37 CTINGVNIKK1862 pKa = 6.77 MTKK1865 pKa = 8.7 TASCPLFAGVTFEE1878 pKa = 4.34 TDD1880 pKa = 3.22 TEE1882 pKa = 4.26 KK1883 pKa = 10.72 LTVSNGWYY1891 pKa = 9.75 HH1892 pKa = 4.07 VTNRR1896 pKa = 11.84 KK1897 pKa = 6.59 VTINKK1902 pKa = 8.72 EE1903 pKa = 3.56 RR1904 pKa = 11.84 FYY1906 pKa = 10.88 PGLTPIIRR1914 pKa = 11.84 WLQLDD1919 pKa = 3.69 IKK1921 pKa = 10.55 EE1922 pKa = 5.23 LILDD1926 pKa = 3.83 SNTNIGWLQVLKK1938 pKa = 11.04 GDD1940 pKa = 3.72 MAHH1943 pKa = 7.05 FLWQLKK1949 pKa = 9.19 EE1950 pKa = 3.91 RR1951 pKa = 11.84 ATQVHH1956 pKa = 6.57 LWLLNFLTEE1965 pKa = 4.12 TDD1967 pKa = 3.92 SPKK1970 pKa = 10.42 CYY1972 pKa = 10.33 YY1973 pKa = 11.15 NNIINTAKK1981 pKa = 9.85 YY1982 pKa = 9.54 NKK1984 pKa = 9.44 AARR1987 pKa = 11.84 SINQPMVTNHH1997 pKa = 6.69 PSVADD2002 pKa = 3.52 HH2003 pKa = 6.8 LNYY2006 pKa = 9.87 IIKK2009 pKa = 9.32 KK2010 pKa = 8.09 QSWIKK2015 pKa = 10.78 KK2016 pKa = 7.55 HH2017 pKa = 5.67 DD2018 pKa = 3.66 TYY2020 pKa = 11.45 ILTNGNQVIIDD2031 pKa = 3.41 ITSNEE2036 pKa = 4.17 EE2037 pKa = 3.49 EE2038 pKa = 4.29 AKK2040 pKa = 9.89 WEE2042 pKa = 3.97 IFAVEE2047 pKa = 4.48 CLADD2051 pKa = 3.69 MVKK2054 pKa = 9.73 TGTGMQGIAAAEE2066 pKa = 3.82 LDD2068 pKa = 4.09 IPGLMIPLHH2077 pKa = 5.86 KK2078 pKa = 10.19 HH2079 pKa = 4.93 LALGTTVQTIINNNLLNLNKK2099 pKa = 8.33 QTRR2102 pKa = 11.84 PGVYY2106 pKa = 9.99 DD2107 pKa = 3.79 VIRR2110 pKa = 11.84 LDD2112 pKa = 3.51 KK2113 pKa = 10.93 QNYY2116 pKa = 8.98 AMQKK2120 pKa = 9.02 HH2121 pKa = 5.08 YY2122 pKa = 10.85 LKK2124 pKa = 10.47 HH2125 pKa = 6.61 RR2126 pKa = 11.84 YY2127 pKa = 8.52 PRR2129 pKa = 11.84 MTITSGNYY2137 pKa = 9.28 EE2138 pKa = 4.4 IINSGIEE2145 pKa = 3.77 LALEE2149 pKa = 3.94 QILLNMRR2156 pKa = 11.84 GGLTEE2161 pKa = 3.94 NSTGIVAYY2169 pKa = 10.49 CGLCPISICMTGKK2182 pKa = 10.33 YY2183 pKa = 9.35 YY2184 pKa = 10.22 IKK2186 pKa = 10.34 IVLPDD2191 pKa = 3.45 VNSNIRR2197 pKa = 11.84 FMYY2200 pKa = 10.54 DD2201 pKa = 3.03 MQKK2204 pKa = 10.21 PQIDD2208 pKa = 3.74 SMLDD2212 pKa = 3.07 NFNAKK2217 pKa = 9.37 RR2218 pKa = 11.84 DD2219 pKa = 4.03 AKK2221 pKa = 10.36 TEE2223 pKa = 4.26 LYY2225 pKa = 9.23 WDD2227 pKa = 4.47 HH2228 pKa = 5.81 EE2229 pKa = 4.96 TKK2231 pKa = 10.61 CEE2233 pKa = 4.12 RR2234 pKa = 11.84 ILAGTSIYY2242 pKa = 11.01 SLTLEE2247 pKa = 4.66 EE2248 pKa = 5.38 ILYY2251 pKa = 10.81 LLDD2254 pKa = 4.82 KK2255 pKa = 9.93 AHH2257 pKa = 6.94 CMYY2260 pKa = 11.13 GWIPTFARR2268 pKa = 11.84 DD2269 pKa = 3.25 TDD2271 pKa = 3.67 EE2272 pKa = 4.21 YY2273 pKa = 11.45 VYY2275 pKa = 10.94 DD2276 pKa = 3.92 RR2277 pKa = 11.84 QLYY2280 pKa = 8.64 CYY2282 pKa = 9.0 GYY2284 pKa = 10.18 RR2285 pKa = 11.84 GGRR2288 pKa = 11.84 VTNKK2292 pKa = 9.17 IRR2294 pKa = 11.84 NDD2296 pKa = 3.53 IIDD2299 pKa = 4.0 KK2300 pKa = 9.91 VNKK2303 pKa = 10.17 GEE2305 pKa = 4.72 PILIKK2310 pKa = 10.23 YY2311 pKa = 8.65 DD2312 pKa = 3.27 KK2313 pKa = 11.14 NEE2315 pKa = 3.92 YY2316 pKa = 10.73 LEE2318 pKa = 4.35 ATVVTEE2324 pKa = 4.08 VFNHH2328 pKa = 6.41 RR2329 pKa = 11.84 LIKK2332 pKa = 10.61 LQFKK2336 pKa = 9.28 PIPVCNYY2343 pKa = 7.85 IDD2345 pKa = 3.88 RR2346 pKa = 11.84 RR2347 pKa = 11.84 LGTYY2351 pKa = 9.15 MDD2353 pKa = 3.99 INNIIKK2359 pKa = 10.22 IKK2361 pKa = 10.46 IPWIDD2366 pKa = 3.51 LDD2368 pKa = 3.94 LFRR2371 pKa = 11.84 VLKK2374 pKa = 10.25 DD2375 pKa = 3.4 RR2376 pKa = 11.84 QIITIKK2382 pKa = 10.38 EE2383 pKa = 3.66 LTINKK2388 pKa = 9.35 RR2389 pKa = 11.84 FLRR2392 pKa = 11.84 NILLRR2397 pKa = 11.84 LMTGDD2402 pKa = 4.02 DD2403 pKa = 3.93 TPHH2406 pKa = 6.94 GALEE2410 pKa = 4.02 YY2411 pKa = 10.88 AKK2413 pKa = 9.24 TLEE2416 pKa = 4.12 STQVITEE2423 pKa = 4.1 KK2424 pKa = 11.13 GIDD2427 pKa = 4.22 DD2428 pKa = 4.07 LTASNLLVTLNTTWYY2443 pKa = 10.5 AIYY2446 pKa = 10.13 IHH2448 pKa = 6.53 NNYY2451 pKa = 9.81 LEE2453 pKa = 4.14 KK2454 pKa = 10.66 FKK2456 pKa = 10.62 TLIHH2460 pKa = 5.95 YY2461 pKa = 9.83 LNYY2464 pKa = 9.53 TDD2466 pKa = 4.04 GRR2468 pKa = 11.84 PVAVLMLEE2476 pKa = 4.21 QILTGIGNLMGMVSDD2491 pKa = 4.09 KK2492 pKa = 11.14 VSDD2495 pKa = 3.26 IAEE2498 pKa = 3.98 QFITYY2503 pKa = 10.3 LNKK2506 pKa = 10.5 NYY2508 pKa = 10.71 NLTNKK2513 pKa = 9.27 MADD2516 pKa = 4.0 CIRR2519 pKa = 11.84 EE2520 pKa = 4.14 AEE2522 pKa = 4.29 KK2523 pKa = 10.66 TNWTPEE2529 pKa = 3.83 TKK2531 pKa = 9.56 QVYY2534 pKa = 9.65 FNRR2537 pKa = 11.84 FYY2539 pKa = 10.92 FSKK2542 pKa = 10.75 DD2543 pKa = 3.12 DD2544 pKa = 3.82 EE2545 pKa = 4.54 FTLRR2549 pKa = 11.84 SWMTGDD2555 pKa = 5.45 DD2556 pKa = 4.76 DD2557 pKa = 6.54 NNDD2560 pKa = 4.01 DD2561 pKa = 5.84 DD2562 pKa = 6.56 DD2563 pKa = 5.87 DD2564 pKa = 5.68 AGKK2567 pKa = 10.49 DD2568 pKa = 3.63 DD2569 pKa = 6.28 DD2570 pKa = 6.32 NVTEE2574 pKa = 4.83 DD2575 pKa = 3.82 NNDD2578 pKa = 3.53 IITTDD2583 pKa = 3.43 STSLPNIGYY2592 pKa = 7.72 EE2593 pKa = 4.81 GPGTSANAEE2602 pKa = 4.08 DD2603 pKa = 4.52 VGTSTTEE2610 pKa = 3.89 LQEE2613 pKa = 4.5 SSTSTTTNDD2622 pKa = 2.77 SDD2624 pKa = 3.92 DD2625 pKa = 4.82 RR2626 pKa = 11.84 IRR2628 pKa = 11.84 KK2629 pKa = 9.37 LMIQPGKK2636 pKa = 9.29 PYY2638 pKa = 10.77 KK2639 pKa = 9.42 NTRR2642 pKa = 11.84 LPIQVMRR2649 pKa = 11.84 FVDD2652 pKa = 3.93 EE2653 pKa = 4.44 KK2654 pKa = 10.63 GATIISRR2661 pKa = 11.84 KK2662 pKa = 5.79 QTIGVLKK2669 pKa = 9.49 TLQLYY2674 pKa = 11.13 GDD2676 pKa = 4.14 FNEE2679 pKa = 4.31 EE2680 pKa = 3.82 QLIKK2684 pKa = 10.28 AAKK2687 pKa = 10.16 LIDD2690 pKa = 4.1 EE2691 pKa = 5.45 DD2692 pKa = 5.21 YY2693 pKa = 10.39 MVHH2696 pKa = 7.34 RR2697 pKa = 11.84 DD2698 pKa = 3.8 LLHH2701 pKa = 6.93 APWNLKK2707 pKa = 8.1 TLSAKK2712 pKa = 10.46 VEE2714 pKa = 4.15 DD2715 pKa = 4.11 ALGVSLEE2722 pKa = 3.93 RR2723 pKa = 11.84 KK2724 pKa = 9.51 YY2725 pKa = 11.21 NEE2727 pKa = 4.47 EE2728 pKa = 4.04 EE2729 pKa = 3.72 PSKK2732 pKa = 11.38 YY2733 pKa = 10.51 NIQLYY2738 pKa = 9.56 SASSGRR2744 pKa = 11.84 DD2745 pKa = 2.99 INISYY2750 pKa = 9.96 SEE2752 pKa = 4.42 HH2753 pKa = 7.1 FMIPKK2758 pKa = 9.91 IIWFYY2763 pKa = 8.45 WHH2765 pKa = 6.24 EE2766 pKa = 4.14 TSVPEE2771 pKa = 5.61 LIMRR2775 pKa = 11.84 CINSWATFNDD2785 pKa = 3.25 SYY2787 pKa = 10.98 MIVVLTKK2794 pKa = 10.32 QEE2796 pKa = 4.0 LSQLIPKK2803 pKa = 9.62 EE2804 pKa = 3.54 ITDD2807 pKa = 3.77 YY2808 pKa = 11.72 VEE2810 pKa = 3.67 NTTPQFASDD2819 pKa = 3.28 WVRR2822 pKa = 11.84 TFVLSRR2828 pKa = 11.84 FGGVWADD2835 pKa = 3.41 ASIICTGTIDD2845 pKa = 3.82 RR2846 pKa = 11.84 LVEE2849 pKa = 3.79 RR2850 pKa = 11.84 TLQNTIGLLQISLGSKK2866 pKa = 6.89 QVKK2869 pKa = 9.8 IKK2871 pKa = 10.08 TSEE2874 pKa = 3.4 NWFIISSTYY2883 pKa = 10.88 NPIITMWNNILTDD2896 pKa = 3.77 LMKK2899 pKa = 9.67 EE2900 pKa = 4.3 TKK2902 pKa = 9.84 PSGEE2906 pKa = 4.22 GCSVWIKK2913 pKa = 10.63 KK2914 pKa = 9.77 KK2915 pKa = 10.9 YY2916 pKa = 7.88 PSEE2919 pKa = 3.82 YY2920 pKa = 10.9 SKK2922 pKa = 9.41 ITKK2925 pKa = 8.99 TMAADD2930 pKa = 3.26 SVDD2933 pKa = 3.57 YY2934 pKa = 10.83 LRR2936 pKa = 11.84 SYY2938 pKa = 10.42 VLEE2941 pKa = 4.68 SIVSQITGLFPEE2953 pKa = 5.48 TICKK2957 pKa = 10.49 DD2958 pKa = 3.25 EE2959 pKa = 4.47 GQLTTFDD2966 pKa = 5.2 DD2967 pKa = 4.88 LPHH2970 pKa = 6.68 SNWDD2974 pKa = 3.72 TLLDD2978 pKa = 3.63 QYY2980 pKa = 7.38 TTKK2983 pKa = 10.36 TKK2985 pKa = 10.56 RR2986 pKa = 11.84 PDD2988 pKa = 3.77 LIIPLVKK2995 pKa = 10.08 MIDD2998 pKa = 3.22 SHH3000 pKa = 8.5 RR3001 pKa = 11.84 IIITDD3006 pKa = 3.71 ALLDD3010 pKa = 4.62 GIKK3013 pKa = 10.41 PEE3015 pKa = 4.35 TGSLLHH3021 pKa = 6.97 EE3022 pKa = 4.62 IYY3024 pKa = 11.28 GMDD3027 pKa = 4.22 FNLKK3031 pKa = 9.98 LHH3033 pKa = 6.41 TLQQVQEE3040 pKa = 4.12 RR3041 pKa = 11.84 LSRR3044 pKa = 11.84 AIKK3047 pKa = 10.55 EE3048 pKa = 3.96 NFEE3051 pKa = 4.05 PVKK3054 pKa = 10.87 KK3055 pKa = 10.38 EE3056 pKa = 3.82 FEE3058 pKa = 4.32 LTRR3061 pKa = 11.84 GLQIFKK3067 pKa = 10.16 TEE3069 pKa = 4.23 FSYY3072 pKa = 11.25 GMAKK3076 pKa = 8.42 LTSMLNNSMTVQEE3089 pKa = 4.2 IQMVRR3094 pKa = 11.84 PALEE3098 pKa = 3.92 FLVKK3102 pKa = 10.3 SGCHH3106 pKa = 5.66 LYY3108 pKa = 8.47 ITEE3111 pKa = 4.12 EE3112 pKa = 4.12 EE3113 pKa = 4.16 LVIMLGMVLGKK3124 pKa = 9.09 MKK3126 pKa = 10.43 HH3127 pKa = 5.27 MKK3129 pKa = 10.04 DD3130 pKa = 3.48 LRR3132 pKa = 11.84 EE3133 pKa = 3.9 EE3134 pKa = 4.01 TQIWVVLEE3142 pKa = 4.99 HH3143 pKa = 6.4 ITDD3146 pKa = 4.07 TKK3148 pKa = 11.07 QIDD3151 pKa = 3.62 LEE3153 pKa = 4.39 KK3154 pKa = 10.24 WFEE3157 pKa = 4.3 TNEE3160 pKa = 4.0 LTTMRR3165 pKa = 11.84 LNVSNRR3171 pKa = 11.84 LPTKK3175 pKa = 9.72 PDD3177 pKa = 3.24 YY3178 pKa = 9.46 VTHH3181 pKa = 6.25 GNRR3184 pKa = 11.84 RR3185 pKa = 11.84 IPKK3188 pKa = 9.4 IVWSYY3193 pKa = 8.25 WDD3195 pKa = 3.38 KK3196 pKa = 11.35 TEE3198 pKa = 3.98 VAEE3201 pKa = 4.91 FQVKK3205 pKa = 9.39 MINNWYY3211 pKa = 9.65 YY3212 pKa = 10.39 HH3213 pKa = 5.19 NQDD3216 pKa = 2.9 YY3217 pKa = 10.92 RR3218 pKa = 11.84 IIILNEE3224 pKa = 3.6 DD3225 pKa = 3.85 TLLKK3229 pKa = 10.08 MVGKK3233 pKa = 8.33 NTHH3236 pKa = 6.46 ALLMRR3241 pKa = 11.84 QTPQFRR3247 pKa = 11.84 SDD3249 pKa = 2.93 WVRR3252 pKa = 11.84 LFILSNFGGVWVDD3265 pKa = 4.24 FSGLFTKK3272 pKa = 10.52 SIHH3275 pKa = 6.08 NLVEE3279 pKa = 4.06 ATVKK3283 pKa = 10.83 NSAGYY3288 pKa = 9.32 CQISLNKK3295 pKa = 9.35 RR3296 pKa = 11.84 TDD3298 pKa = 2.97 KK3299 pKa = 11.15 KK3300 pKa = 10.7 IVLEE3304 pKa = 4.07 SWLIICVEE3312 pKa = 4.03 NCKK3315 pKa = 9.82 TIQSWFDD3322 pKa = 3.13 EE3323 pKa = 4.65 TKK3325 pKa = 10.94 EE3326 pKa = 3.76 MTKK3329 pKa = 10.49 FVDD3332 pKa = 3.77 PSGYY3336 pKa = 10.15 NALEE3340 pKa = 4.31 WMTSTYY3346 pKa = 10.42 GSEE3349 pKa = 3.92 YY3350 pKa = 10.6 QLAKK3354 pKa = 10.59 EE3355 pKa = 4.19 YY3356 pKa = 10.42 ILPNLRR3362 pKa = 11.84 TYY3364 pKa = 10.9 LRR3366 pKa = 11.84 VYY3368 pKa = 9.73 IIQVIVRR3375 pKa = 11.84 LRR3377 pKa = 11.84 VKK3379 pKa = 10.26 DD3380 pKa = 3.91 DD3381 pKa = 3.56 PVIIYY3386 pKa = 10.27 SDD3388 pKa = 3.67 EE3389 pKa = 4.6 ANVSMFHH3396 pKa = 6.35 NLSANAWLNLWDD3408 pKa = 4.13 YY3409 pKa = 11.34 VATKK3413 pKa = 9.89 PKK3415 pKa = 10.57 VEE3417 pKa = 4.22 IDD3419 pKa = 3.34 VGVPFIKK3426 pKa = 10.09 WIGIQRR3432 pKa = 11.84 SIIIEE3437 pKa = 4.05 NYY3439 pKa = 8.81 NCHH3442 pKa = 5.98 HH3443 pKa = 6.87 HH3444 pKa = 6.92 NITPISLLGEE3454 pKa = 4.04 EE3455 pKa = 4.95 LNYY3458 pKa = 10.42 PSITYY3463 pKa = 10.7 NVMSNAEE3470 pKa = 3.87 LTLPNRR3476 pKa = 11.84 EE3477 pKa = 3.58 GSTTKK3482 pKa = 9.26 KK3483 pKa = 8.71 TNNIIINKK3491 pKa = 5.75 YY3492 pKa = 6.6 TNCKK3496 pKa = 8.4 TLLICVGSAGDD3507 pKa = 3.51 VLQFKK3512 pKa = 9.25 TIYY3515 pKa = 10.3 EE3516 pKa = 4.16 IADD3519 pKa = 3.61 SEE3521 pKa = 4.52 GQSPVIITHH3530 pKa = 6.9 KK3531 pKa = 10.53 DD3532 pKa = 2.84 HH3533 pKa = 7.68 SKK3535 pKa = 10.41 YY3536 pKa = 10.59 FEE3538 pKa = 4.24 NKK3540 pKa = 7.6 KK3541 pKa = 10.06 AHH3543 pKa = 5.7 YY3544 pKa = 9.71 FDD3546 pKa = 4.44 VEE3548 pKa = 4.34 SEE3550 pKa = 4.06 EE3551 pKa = 5.29 LMALVNIVLNEE3562 pKa = 3.36 VDD3564 pKa = 3.63 LWMDD3568 pKa = 3.45 IKK3570 pKa = 10.94 ASHH3573 pKa = 7.16 LVRR3576 pKa = 11.84 QISDD3580 pKa = 4.51 DD3581 pKa = 3.01 ITAIARR3587 pKa = 11.84 NYY3589 pKa = 8.08 EE3590 pKa = 3.95 QIIEE3594 pKa = 4.14 KK3595 pKa = 10.59 VIVNSAVPNLTEE3607 pKa = 4.38 LGKK3610 pKa = 9.31 MLPCDD3615 pKa = 3.52 WLEE3618 pKa = 3.91 VSTFTDD3624 pKa = 2.82 NVVFNPKK3631 pKa = 8.46 KK3632 pKa = 7.24 TTGLKK3637 pKa = 10.55 GSILRR3642 pKa = 11.84 AKK3644 pKa = 9.76 EE3645 pKa = 3.88 WLHH3648 pKa = 6.51 HH3649 pKa = 6.18 NIIKK3653 pKa = 10.44 SEE3655 pKa = 4.01 LKK3657 pKa = 10.23 EE3658 pKa = 3.93 EE3659 pKa = 4.25 NVRR3662 pKa = 11.84 SLRR3665 pKa = 11.84 KK3666 pKa = 9.25 FCSGYY3671 pKa = 9.61 PLFYY3675 pKa = 9.67 PYY3677 pKa = 11.1 VMSVCGPLTIWSMPSNHH3694 pKa = 6.14 NEE3696 pKa = 4.02 MIMSEE3701 pKa = 4.1 QDD3703 pKa = 3.27 VLITFGSCDD3712 pKa = 3.21 NTITTKK3718 pKa = 10.89 SKK3720 pKa = 10.55 IKK3722 pKa = 10.45 LIEE3725 pKa = 3.82 NFIDD3729 pKa = 3.25 CGYY3732 pKa = 10.56 RR3733 pKa = 11.84 VTYY3736 pKa = 9.11 HH3737 pKa = 7.45 DD3738 pKa = 4.89 KK3739 pKa = 11.07 YY3740 pKa = 10.95 QIAVPGSVLFNAMEE3754 pKa = 4.0 QYY3756 pKa = 9.73 PGKK3759 pKa = 10.53 FGIVNNYY3766 pKa = 8.69 DD3767 pKa = 3.21 LRR3769 pKa = 11.84 SVKK3772 pKa = 10.17 GGKK3775 pKa = 8.96 FVLVTHH3781 pKa = 7.04 GGHH3784 pKa = 5.05 GTIMEE3789 pKa = 4.68 ALLTNCKK3796 pKa = 10.02 IMIHH3800 pKa = 6.64 PIIADD3805 pKa = 3.35 QFSICDD3811 pKa = 3.38 TMVQQRR3817 pKa = 11.84 MAVKK3821 pKa = 9.09 LTDD3824 pKa = 3.17 ITNVNDD3830 pKa = 3.33 CRR3832 pKa = 11.84 QAIAGLNRR3840 pKa = 11.84 LIDD3843 pKa = 3.31 TTLAVKK3849 pKa = 9.8 PVISVFFKK3857 pKa = 10.95 PLIFWLKK3864 pKa = 9.85 PEE3866 pKa = 4.19 YY3867 pKa = 10.68 KK3868 pKa = 9.29 IDD3870 pKa = 4.47 SPDD3873 pKa = 3.35 EE3874 pKa = 3.92 TLKK3877 pKa = 10.92 ILDD3880 pKa = 4.27 DD3881 pKa = 4.37 AEE3883 pKa = 4.56 VMGDD3887 pKa = 3.56 YY3888 pKa = 11.2 DD3889 pKa = 3.9 NVGSGIYY3896 pKa = 9.91 RR3897 pKa = 11.84 ILDD3900 pKa = 3.35 VEE3902 pKa = 4.25 HH3903 pKa = 6.76 QILYY3907 pKa = 10.36 DD3908 pKa = 3.51 PQVPNRR3914 pKa = 11.84 CVTHH3918 pKa = 6.55 SLEE3921 pKa = 4.24 YY3922 pKa = 9.44 MLQGSGQEE3930 pKa = 4.97 KK3931 pKa = 10.55 YY3932 pKa = 9.11 LTCNTIAVMRR3942 pKa = 11.84 LQQHH3946 pKa = 5.54 SVTEE3950 pKa = 3.92 QEE3952 pKa = 5.06 LIDD3955 pKa = 4.34 GVLSMGVNVILVYY3968 pKa = 11.21 SNGTGLVVKK3977 pKa = 9.09 TMNGPTMCFYY3987 pKa = 11.21 VDD3989 pKa = 3.66 RR3990 pKa = 11.84 SRR3992 pKa = 11.84 TPWHH3996 pKa = 5.52 VCAARR4001 pKa = 11.84 LVKK4004 pKa = 10.42 HH4005 pKa = 6.13 GEE4007 pKa = 4.18 VIDD4010 pKa = 3.98 LMKK4013 pKa = 10.69 RR4014 pKa = 11.84 NAFIRR4019 pKa = 11.84 EE4020 pKa = 4.22 LPHH4023 pKa = 8.49 SIDD4026 pKa = 3.52 YY4027 pKa = 9.68 EE4028 pKa = 4.11 INEE4031 pKa = 3.95 LHH4033 pKa = 6.83 KK4034 pKa = 11.1 NFSTAMLCIPKK4045 pKa = 10.48 LMAQQFGKK4053 pKa = 10.72 SFFKK4057 pKa = 11.1 NFLARR4062 pKa = 11.84 TKK4064 pKa = 9.62 STNLQVLSSRR4074 pKa = 11.84 TDD4076 pKa = 2.96 LHH4078 pKa = 5.99 VAYY4081 pKa = 8.61 ITIKK4085 pKa = 9.61 QHH4087 pKa = 5.08 FDD4089 pKa = 2.26 AWIGDD4094 pKa = 4.11 TIYY4097 pKa = 10.53 PDD4099 pKa = 3.5 TPLGVGWVITAQGWVLANYY4118 pKa = 8.54 FIKK4121 pKa = 10.8 DD4122 pKa = 3.57 GIIVVFSDD4130 pKa = 5.19 DD4131 pKa = 4.59 GILEE4135 pKa = 3.96 QTILINLHH4143 pKa = 5.09 LQYY4146 pKa = 10.39 PVEE4149 pKa = 4.04 RR4150 pKa = 11.84 SKK4152 pKa = 11.51 SVILSTKK4159 pKa = 10.24 QEE4161 pKa = 4.13 LVSLNKK4167 pKa = 8.32 PTIMYY4172 pKa = 7.45 TTLNHH4177 pKa = 5.87 CVPRR4181 pKa = 11.84 SSNLVSNFHH4190 pKa = 6.35 KK4191 pKa = 10.88 QNILIVADD4199 pKa = 3.99 FDD4201 pKa = 3.9 NRR4203 pKa = 11.84 KK4204 pKa = 8.75 HH4205 pKa = 7.18 HH4206 pKa = 6.46 MFDD4209 pKa = 3.12 EE4210 pKa = 4.11 MDD4212 pKa = 3.83 MIKK4215 pKa = 10.29 RR4216 pKa = 11.84 AAKK4219 pKa = 10.43 VIFHH4223 pKa = 6.26 TNKK4226 pKa = 9.72 QIKK4229 pKa = 9.9 VEE4231 pKa = 4.25 DD4232 pKa = 3.79 LASSHH4237 pKa = 6.03 NAPLNRR4243 pKa = 11.84 MVIKK4247 pKa = 10.06 QGKK4250 pKa = 8.03 VLYY4253 pKa = 9.6 EE4254 pKa = 3.98 HH4255 pKa = 6.86 EE4256 pKa = 4.85 FEE4258 pKa = 4.12 EE4259 pKa = 5.58 KK4260 pKa = 8.74 MRR4262 pKa = 11.84 QRR4264 pKa = 11.84 QVVKK4268 pKa = 10.79 LFGLNVMSEE4277 pKa = 4.29 QQCITASPLTEE4288 pKa = 3.73 EE4289 pKa = 4.37 QINYY4293 pKa = 8.11 IYY4295 pKa = 10.63 KK4296 pKa = 10.31 YY4297 pKa = 10.21 FVKK4300 pKa = 10.55 SGNKK4304 pKa = 9.14 LVAIDD4309 pKa = 3.7 NEE4311 pKa = 4.61 SYY4313 pKa = 10.79 NDD4315 pKa = 3.91 KK4316 pKa = 10.44 EE4317 pKa = 4.48 IKK4319 pKa = 10.09 PSDD4322 pKa = 3.27 WVITLIQNSEE4332 pKa = 4.0 VMSNDD4337 pKa = 3.44 VINNLIKK4344 pKa = 10.42 LVKK4347 pKa = 8.82 EE4348 pKa = 3.52 HH4349 pKa = 6.56 SMWHH4353 pKa = 6.88 IYY4355 pKa = 9.17 DD4356 pKa = 3.24 QHH4358 pKa = 8.02 NYY4360 pKa = 8.43 EE4361 pKa = 5.07 LSMTQAGDD4369 pKa = 3.67 VVTLEE4374 pKa = 5.59 HH4375 pKa = 6.74 GDD4377 pKa = 3.71 LWVKK4381 pKa = 10.57 SYY4383 pKa = 11.33 GIVLVYY4389 pKa = 10.44 VRR4391 pKa = 11.84 VGGQRR4396 pKa = 11.84 EE4397 pKa = 4.02 RR4398 pKa = 11.84 LSWKK4402 pKa = 10.24 LDD4404 pKa = 3.29 TDD4406 pKa = 3.81 SAQINNPKK4414 pKa = 9.99 PGDD4417 pKa = 2.95 WWGLEE4422 pKa = 4.04 TKK4424 pKa = 8.9 TQTKK4428 pKa = 10.27 VNSNFKK4434 pKa = 10.53 NVLAINEE4441 pKa = 4.31 LKK4443 pKa = 10.3 YY4444 pKa = 10.66 HH4445 pKa = 5.78 EE4446 pKa = 5.32 PEE4448 pKa = 3.94 TLLVDD4453 pKa = 3.92 GSNVVEE4459 pKa = 5.02 SDD4461 pKa = 4.5 DD4462 pKa = 4.63 LLDD4465 pKa = 3.96 MYY4467 pKa = 10.61 IPPYY4471 pKa = 9.95 HH4472 pKa = 6.41 YY4473 pKa = 10.22 GYY4475 pKa = 8.28 TGSVIEE4481 pKa = 4.82 PLLDD4485 pKa = 4.04 FPDD4488 pKa = 4.65 NIAMQLWEE4496 pKa = 5.15 DD4497 pKa = 3.75 TDD4499 pKa = 3.71 QTDD4502 pKa = 3.3 WLSLYY4507 pKa = 10.64 APSNQCQLKK4516 pKa = 10.37 SRR4518 pKa = 11.84 EE4519 pKa = 4.18 LPGKK4523 pKa = 10.09 IIQTEE4528 pKa = 4.5 KK4529 pKa = 9.44 ITLTKK4534 pKa = 9.67 WPIRR4538 pKa = 11.84 SRR4540 pKa = 11.84 AVLTKK4545 pKa = 9.98 VCFEE4549 pKa = 4.37 EE4550 pKa = 5.04 GRR4552 pKa = 11.84 SILGRR4557 pKa = 11.84 MKK4559 pKa = 10.14 SVAFIRR4565 pKa = 11.84 TVTPDD4570 pKa = 3.39 PYY4572 pKa = 11.24 KK4573 pKa = 10.87 LVMDD4577 pKa = 4.06 MADD4580 pKa = 3.12 TYY4582 pKa = 10.77 FIKK4585 pKa = 10.68 GWVTKK4590 pKa = 10.65 VNEE4593 pKa = 4.01 FRR4595 pKa = 11.84 AKK4597 pKa = 10.25 RR4598 pKa = 11.84 LVILPEE4604 pKa = 4.04 DD4605 pKa = 3.53 VKK4607 pKa = 11.09 RR4608 pKa = 11.84 WVEE4611 pKa = 3.96 TNKK4614 pKa = 9.98 DD4615 pKa = 3.28 AKK4617 pKa = 10.57 RR4618 pKa = 11.84 IEE4620 pKa = 4.31 PEE4622 pKa = 3.91 LLEE4625 pKa = 4.38 LLSGEE4630 pKa = 4.16 ILVKK4634 pKa = 10.52 PMNDD4638 pKa = 3.08 VNIHH4642 pKa = 6.41 LKK4644 pKa = 10.85 LEE4646 pKa = 4.24 SLLKK4650 pKa = 11.01 DD4651 pKa = 3.16 NTTIMTKK4658 pKa = 8.07 QQQARR4663 pKa = 11.84 IIVWQRR4669 pKa = 11.84 KK4670 pKa = 7.41 AVCAIYY4676 pKa = 10.95 SNLFVKK4682 pKa = 10.76 VKK4684 pKa = 10.75 DD4685 pKa = 3.62 RR4686 pKa = 11.84 LKK4688 pKa = 11.0 SILHH4692 pKa = 6.45 DD4693 pKa = 4.52 KK4694 pKa = 10.5 IIYY4697 pKa = 10.32 ADD4699 pKa = 3.68 GLRR4702 pKa = 11.84 PDD4704 pKa = 4.57 EE4705 pKa = 3.95 ISARR4709 pKa = 11.84 VRR4711 pKa = 11.84 LCKK4714 pKa = 10.5 DD4715 pKa = 2.48 IAGFFEE4721 pKa = 5.17 NDD4723 pKa = 2.82 LTKK4726 pKa = 10.25 QDD4728 pKa = 3.96 RR4729 pKa = 11.84 QTDD4732 pKa = 3.65 APIITTEE4739 pKa = 3.59 MYY4741 pKa = 9.69 MYY4743 pKa = 10.73 DD4744 pKa = 3.84 LLGVHH4749 pKa = 6.84 PNVIASWRR4757 pKa = 11.84 EE4758 pKa = 3.5 MHH4760 pKa = 6.21 EE4761 pKa = 3.75 VWRR4764 pKa = 11.84 FKK4766 pKa = 11.19 SNHH4769 pKa = 5.05 YY4770 pKa = 8.83 WGQGQGMRR4778 pKa = 11.84 LTGQATTAIGNCITNLQVHH4797 pKa = 5.24 QEE4799 pKa = 4.06 FVKK4802 pKa = 10.92 KK4803 pKa = 10.42 NFSILEE4809 pKa = 4.03 LALFLGDD4816 pKa = 3.87 DD4817 pKa = 3.26 MCMVFRR4823 pKa = 11.84 EE4824 pKa = 4.3 KK4825 pKa = 10.64 PDD4827 pKa = 3.5 TKK4829 pKa = 10.93 NLRR4832 pKa = 11.84 KK4833 pKa = 10.3 NIATKK4838 pKa = 10.73 FNMQSKK4844 pKa = 9.79 DD4845 pKa = 2.44 AWYY4848 pKa = 10.5 RR4849 pKa = 11.84 NGATFCSMVMSRR4861 pKa = 11.84 TPTGAEE4867 pKa = 3.73 LCPDD4871 pKa = 3.65 VVRR4874 pKa = 11.84 LKK4876 pKa = 10.62 FRR4878 pKa = 11.84 YY4879 pKa = 8.49 EE4880 pKa = 3.97 VTNGVHH4886 pKa = 6.01 EE4887 pKa = 4.82 ANAEE4891 pKa = 4.1 NILMRR4896 pKa = 11.84 KK4897 pKa = 9.44 ASYY4900 pKa = 11.27 IMMLGEE4906 pKa = 4.38 GPNVKK4911 pKa = 8.59 EE4912 pKa = 4.25 TVTKK4916 pKa = 10.75 LNLPIKK4922 pKa = 9.72 PLVWYY4927 pKa = 9.65 DD4928 pKa = 3.48 FEE4930 pKa = 5.58 SMLRR4934 pKa = 11.84 AVGDD4938 pKa = 3.97 KK4939 pKa = 10.76 YY4940 pKa = 11.69 DD4941 pKa = 3.61 MSHH4944 pKa = 5.54 VQVLDD4949 pKa = 3.32 VYY4951 pKa = 11.34 YY4952 pKa = 11.23 NLLQMLNSEE4961 pKa = 3.98 KK4962 pKa = 10.58 LYY4964 pKa = 10.41 RR4965 pKa = 11.84 HH4966 pKa = 5.98 TFRR4969 pKa = 11.84 HH4970 pKa = 5.82 FSNIEE4975 pKa = 3.66 GKK4977 pKa = 10.26
Molecular weight: 572.58 kDa
Isoelectric point according different methods:
IPC2.protein.svr19 6.025
IPC2_protein 6.02
IPC_protein 6.084
Toseland 6.44
ProMoST 6.491
Dawson 6.402
Bjellqvist 6.415
Wikipedia 6.415
Rodwell 6.389
Grimsley 6.59
Solomon 6.402
Lehninger 6.402
Nozaki 6.693
DTASelect 6.868
Thurlkill 6.883
EMBOSS 6.854
Sillero 6.781
Patrickios 4.151
IPC_peptide 6.415
IPC2_peptide 6.664
IPC2.peptide.svr19 6.711
Protein with the highest isoelectric point:
>tr|A0A1S7D814|A0A1S7D814_9VIRU Polyprotein OS=Lagenaria siceraria endornavirus-Hubei OX=1965306 PE=4 SV=1
MM1 pKa = 7.38 QMNTDD6 pKa = 4.51 AITPYY11 pKa = 9.76 KK12 pKa = 10.11 RR13 pKa = 11.84 KK14 pKa = 10.58 YY15 pKa = 9.08 KK16 pKa = 10.49 DD17 pKa = 3.0 KK18 pKa = 10.68 PLRR21 pKa = 11.84 LLNKK25 pKa = 9.4 EE26 pKa = 4.29 FSNHH30 pKa = 3.85 LQGWIKK36 pKa = 10.61 LPRR39 pKa = 11.84 NQSVTINKK47 pKa = 9.14 NPWIKK52 pKa = 10.65 SFQKK56 pKa = 10.36 LFKK59 pKa = 10.38 DD60 pKa = 3.3 KK61 pKa = 10.85 RR62 pKa = 11.84 EE63 pKa = 4.38 HH64 pKa = 7.45 IFDD67 pKa = 3.8 NNKK70 pKa = 10.21 LKK72 pKa = 10.68 LVPAIRR78 pKa = 11.84 GEE80 pKa = 4.0 RR81 pKa = 11.84 KK82 pKa = 9.47 IRR84 pKa = 11.84 DD85 pKa = 3.73 TVGTVATNVTYY96 pKa = 10.73 DD97 pKa = 3.67 DD98 pKa = 4.13 GLGNVINFNEE108 pKa = 4.56 LHH110 pKa = 6.51 PMDD113 pKa = 4.17 VVKK116 pKa = 10.56 ILYY119 pKa = 9.24 NVNCLGIEE127 pKa = 4.1 LWKK130 pKa = 10.43 SDD132 pKa = 3.77 YY133 pKa = 10.06 YY134 pKa = 10.87 TIQDD138 pKa = 3.87 YY139 pKa = 10.75 IDD141 pKa = 3.72 KK142 pKa = 10.53 VKK144 pKa = 10.62 HH145 pKa = 6.29 LEE147 pKa = 4.25 LDD149 pKa = 3.68 DD150 pKa = 4.9 DD151 pKa = 4.63 EE152 pKa = 6.86 KK153 pKa = 11.64 DD154 pKa = 3.63 EE155 pKa = 5.35 EE156 pKa = 4.73 DD157 pKa = 5.9 FLDD160 pKa = 5.69 EE161 pKa = 6.81 DD162 pKa = 5.06 DD163 pKa = 6.36 LDD165 pKa = 4.47 DD166 pKa = 4.61 KK167 pKa = 11.63 LIIKK171 pKa = 7.56 MVKK174 pKa = 9.31 PGRR177 pKa = 11.84 GNCTSEE183 pKa = 4.21 ILLALDD189 pKa = 4.88 KK190 pKa = 10.64 ILKK193 pKa = 10.08 RR194 pKa = 11.84 FGGFEE199 pKa = 3.8 GYY201 pKa = 10.89 YY202 pKa = 10.51 NYY204 pKa = 10.5 FLEE207 pKa = 4.08 NHH209 pKa = 6.51 FKK211 pKa = 10.67 HH212 pKa = 6.57 FGYY215 pKa = 10.49 LEE217 pKa = 4.42 CVDD220 pKa = 3.93 GSYY223 pKa = 11.12 DD224 pKa = 3.43 FHH226 pKa = 8.03 SVKK229 pKa = 10.41 FNPLKK234 pKa = 10.46 VCGVCGRR241 pKa = 11.84 VNHH244 pKa = 5.86 YY245 pKa = 10.61 NQFNRR250 pKa = 11.84 GLRR253 pKa = 11.84 QVHH256 pKa = 5.79 YY257 pKa = 10.33 SLSHH261 pKa = 5.48 YY262 pKa = 8.74 KK263 pKa = 10.14 QKK265 pKa = 11.1 SKK267 pKa = 10.92 AIKK270 pKa = 10.03 EE271 pKa = 4.21 DD272 pKa = 3.56 FLTEE276 pKa = 3.8 FDD278 pKa = 3.85 EE279 pKa = 4.45 HH280 pKa = 6.8 HH281 pKa = 7.02 KK282 pKa = 8.76 PTNIPWRR289 pKa = 11.84 CGYY292 pKa = 10.24 CFSDD296 pKa = 3.56 LNYY299 pKa = 10.25 VVLIEE304 pKa = 4.38 KK305 pKa = 10.78 YY306 pKa = 10.08 MMVKK310 pKa = 10.43 LIEE313 pKa = 4.29 YY314 pKa = 8.79 VCNHH318 pKa = 6.42 LFVLQGDD325 pKa = 4.24 IEE327 pKa = 4.35 QLMKK331 pKa = 10.2 IGYY334 pKa = 9.45 GDD336 pKa = 3.34 IYY338 pKa = 11.0 EE339 pKa = 5.02 DD340 pKa = 5.11 LDD342 pKa = 3.86 IKK344 pKa = 11.07 DD345 pKa = 3.58 KK346 pKa = 11.16 EE347 pKa = 4.44 AIKK350 pKa = 10.69 SHH352 pKa = 7.09 DD353 pKa = 3.98 EE354 pKa = 3.89 IVVNNYY360 pKa = 9.5 FYY362 pKa = 10.85 HH363 pKa = 5.25 SQRR366 pKa = 11.84 KK367 pKa = 8.33 IVTVGQDD374 pKa = 2.73 FDD376 pKa = 4.13 AASHH380 pKa = 6.03 RR381 pKa = 11.84 VINDD385 pKa = 3.18 VLGGCYY391 pKa = 9.45 FRR393 pKa = 11.84 PTSKK397 pKa = 10.69 LNSIKK402 pKa = 10.59 PEE404 pKa = 4.81 FIAEE408 pKa = 4.45 LSTFSEE414 pKa = 4.45 IIEE417 pKa = 4.17 RR418 pKa = 11.84 TLVGRR423 pKa = 11.84 DD424 pKa = 3.43 IVCLGNVLPGTNRR437 pKa = 11.84 TNVHH441 pKa = 5.06 NWYY444 pKa = 10.34 HH445 pKa = 4.99 NQTWFSKK452 pKa = 10.51 DD453 pKa = 3.45 PEE455 pKa = 4.65 VMCSSKK461 pKa = 10.79 GICGHH466 pKa = 5.7 NKK468 pKa = 9.98 NYY470 pKa = 9.82 FVYY473 pKa = 10.62 GNVGMMGQPLNNILNIVEE491 pKa = 4.32 GQRR494 pKa = 11.84 ALQFITPIMTATRR507 pKa = 11.84 TLPDD511 pKa = 3.42 STGMFQRR518 pKa = 11.84 TEE520 pKa = 4.18 DD521 pKa = 3.65 NLNFYY526 pKa = 10.98 LDD528 pKa = 4.11 GNPVPINFMTDD539 pKa = 2.41 TYY541 pKa = 11.53 NALNNYY547 pKa = 9.31 QIIKK551 pKa = 9.06 WDD553 pKa = 3.31 RR554 pKa = 11.84 KK555 pKa = 8.63 LFYY558 pKa = 10.69 VVEE561 pKa = 4.36 VKK563 pKa = 10.55 KK564 pKa = 11.26 LNLTRR569 pKa = 11.84 LMTIVGPFNDD579 pKa = 4.3 TIDD582 pKa = 3.87 YY583 pKa = 8.26 PRR585 pKa = 11.84 LMVDD589 pKa = 3.07 NEE591 pKa = 4.05 RR592 pKa = 11.84 GIKK595 pKa = 9.46 IRR597 pKa = 11.84 IRR599 pKa = 11.84 LPDD602 pKa = 3.56 IDD604 pKa = 4.72 SFMGKK609 pKa = 7.75 TKK611 pKa = 10.49 GLNYY615 pKa = 9.75 QPKK618 pKa = 8.52 TFEE621 pKa = 4.51 LNVNLFRR628 pKa = 11.84 YY629 pKa = 10.28 LCMRR633 pKa = 11.84 NLNRR637 pKa = 11.84 KK638 pKa = 8.64 VSHH641 pKa = 5.56 EE642 pKa = 4.05 TLRR645 pKa = 11.84 PYY647 pKa = 11.1 AVGFSMRR654 pKa = 11.84 RR655 pKa = 11.84 FVVHH659 pKa = 6.48 NKK661 pKa = 9.71 VISNPTIAYY670 pKa = 7.63 EE671 pKa = 4.28 DD672 pKa = 4.32 LDD674 pKa = 3.4 MHH676 pKa = 6.89 IILSRR681 pKa = 11.84 VCMMKK686 pKa = 10.54 LKK688 pKa = 10.33 NCFEE692 pKa = 4.1 ISHH695 pKa = 6.51 NYY697 pKa = 9.49 SKK699 pKa = 11.09 ALKK702 pKa = 10.17 LLGPFRR708 pKa = 11.84 SMVGDD713 pKa = 3.63 MEE715 pKa = 4.65 SALTASMIGLIGEE728 pKa = 4.2 ILEE731 pKa = 4.31 NTLGLKK737 pKa = 9.15 WDD739 pKa = 4.3 AVLSMLDD746 pKa = 3.55 GARR749 pKa = 11.84 LQSMLMGVGKK759 pKa = 10.49 EE760 pKa = 4.25 DD761 pKa = 3.33 FWEE764 pKa = 4.38 HH765 pKa = 7.02 LLQLTEE771 pKa = 4.93 NITTVPPKK779 pKa = 9.97 ILDD782 pKa = 3.72 MEE784 pKa = 4.35 RR785 pKa = 11.84 HH786 pKa = 4.9 TEE788 pKa = 3.99 EE789 pKa = 4.98 EE790 pKa = 3.82 ITFALQNCMHH800 pKa = 6.92 HH801 pKa = 7.16 SIEE804 pKa = 4.49 CNHH807 pKa = 5.43 VRR809 pKa = 11.84 VKK811 pKa = 10.98 ADD813 pKa = 4.18 NRR815 pKa = 11.84 CCCCNLPITDD825 pKa = 4.26 EE826 pKa = 4.22 LFCNVVNPNPVSNEE840 pKa = 3.72 PYY842 pKa = 7.98 FTPNVYY848 pKa = 9.75 EE849 pKa = 4.08 VEE851 pKa = 4.3 PEE853 pKa = 4.03 RR854 pKa = 11.84 EE855 pKa = 3.91 EE856 pKa = 3.88 QQIGNIEE863 pKa = 3.87 KK864 pKa = 10.84 DD865 pKa = 3.52 KK866 pKa = 11.32 IVDD869 pKa = 3.54 NLANRR874 pKa = 11.84 IMLAMRR880 pKa = 11.84 DD881 pKa = 3.33 TSIRR885 pKa = 11.84 DD886 pKa = 3.11 RR887 pKa = 11.84 RR888 pKa = 11.84 VQPKK892 pKa = 10.39 GPYY895 pKa = 9.45 KK896 pKa = 10.67 LPLEE900 pKa = 4.25 QPPVTKK906 pKa = 9.67 ITPDD910 pKa = 3.05 NARR913 pKa = 11.84 ITEE916 pKa = 4.07 KK917 pKa = 11.27 ANVEE921 pKa = 4.0 EE922 pKa = 4.66 SKK924 pKa = 9.37 PTVDD928 pKa = 4.19 IKK930 pKa = 9.73 VTKK933 pKa = 10.51 SKK935 pKa = 9.93 TSSFKK940 pKa = 11.13 SKK942 pKa = 9.32 TSSIGEE948 pKa = 4.04 PPQNAEE954 pKa = 3.32 GWQKK958 pKa = 9.85 VLRR961 pKa = 11.84 RR962 pKa = 11.84 GKK964 pKa = 10.08 EE965 pKa = 3.77 KK966 pKa = 9.52 PTDD969 pKa = 3.29 IANAILDD976 pKa = 4.25 NIMEE980 pKa = 4.37 NAEE983 pKa = 4.27 RR984 pKa = 11.84 LTISTDD990 pKa = 2.99 NVEE993 pKa = 4.99 AINMLGYY1000 pKa = 10.8 DD1001 pKa = 4.37 FVRR1004 pKa = 11.84 HH1005 pKa = 5.64 CCEE1008 pKa = 3.55 TVQYY1012 pKa = 11.16 EE1013 pKa = 4.04 NDD1015 pKa = 3.52 LNNGVNEE1022 pKa = 4.5 IYY1024 pKa = 10.6 YY1025 pKa = 10.33 LPHH1028 pKa = 7.11 LPTGSLILPRR1038 pKa = 11.84 DD1039 pKa = 3.42 SFEE1042 pKa = 6.07 IIDD1045 pKa = 4.11 KK1046 pKa = 10.92 VYY1048 pKa = 10.51 IPNSGPLTCAFDD1060 pKa = 4.46 AYY1062 pKa = 10.6 HH1063 pKa = 6.91 FSTEE1067 pKa = 4.05 PGSLQEE1073 pKa = 4.62 MIDD1076 pKa = 3.35 IVGAQPPFSTEE1087 pKa = 3.77 HH1088 pKa = 6.22 LSLYY1092 pKa = 10.68 AKK1094 pKa = 8.87 WRR1096 pKa = 11.84 KK1097 pKa = 9.52 DD1098 pKa = 3.33 NIMILDD1104 pKa = 4.36 DD1105 pKa = 3.62 NHH1107 pKa = 6.3 VHH1109 pKa = 5.53 VEE1111 pKa = 3.87 KK1112 pKa = 10.9 HH1113 pKa = 5.68 NEE1115 pKa = 3.88 SSNTFAVIQFEE1126 pKa = 4.24 HH1127 pKa = 7.06 GEE1129 pKa = 4.15 TNADD1133 pKa = 2.97 IGHH1136 pKa = 7.03 FLPVTIKK1143 pKa = 10.28 RR1144 pKa = 11.84 VKK1146 pKa = 8.15 PTPIYY1151 pKa = 10.18 FYY1153 pKa = 10.8 HH1154 pKa = 7.43 RR1155 pKa = 11.84 DD1156 pKa = 3.24 PNAIVEE1162 pKa = 4.16 RR1163 pKa = 11.84 DD1164 pKa = 3.63 HH1165 pKa = 7.35 IVKK1168 pKa = 9.89 NRR1170 pKa = 11.84 YY1171 pKa = 8.72 GKK1173 pKa = 9.7 MYY1175 pKa = 10.66 SSTCLPTWSPKK1186 pKa = 10.83 DD1187 pKa = 3.57 NLSCEE1192 pKa = 3.98 ITYY1195 pKa = 10.78 HH1196 pKa = 6.55 NITVDD1201 pKa = 3.39 VRR1203 pKa = 11.84 VSEE1206 pKa = 4.59 AIKK1209 pKa = 9.94 PLKK1212 pKa = 10.21 LEE1214 pKa = 4.44 KK1215 pKa = 10.1 IEE1217 pKa = 4.11 NEE1219 pKa = 3.71 WYY1221 pKa = 8.39 LTNNLEE1227 pKa = 4.36 TRR1229 pKa = 11.84 LHH1231 pKa = 6.83 LIDD1234 pKa = 4.75 KK1235 pKa = 9.64 EE1236 pKa = 4.26 KK1237 pKa = 10.58 IHH1239 pKa = 6.97 AKK1241 pKa = 9.68 LPKK1244 pKa = 9.81 IFEE1247 pKa = 4.37 KK1248 pKa = 10.84 YY1249 pKa = 9.12 ISKK1252 pKa = 10.08 IEE1254 pKa = 3.91 YY1255 pKa = 10.37 GLALKK1260 pKa = 10.6 LPSNEE1265 pKa = 3.49 IEE1267 pKa = 4.39 EE1268 pKa = 4.14 YY1269 pKa = 10.36 RR1270 pKa = 11.84 HH1271 pKa = 6.09 IDD1273 pKa = 3.05 KK1274 pKa = 10.42 EE1275 pKa = 4.39 LPVNYY1280 pKa = 8.0 EE1281 pKa = 4.03 TEE1283 pKa = 4.22 LEE1285 pKa = 4.18 AEE1287 pKa = 4.23 LLEE1290 pKa = 4.07 ILRR1293 pKa = 11.84 VFARR1297 pKa = 11.84 LSEE1300 pKa = 4.26 LAGQVPFRR1308 pKa = 11.84 DD1309 pKa = 3.21 IKK1311 pKa = 9.83 QTHH1314 pKa = 5.7 QGHH1317 pKa = 5.99 ISSWFGKK1324 pKa = 10.21 SKK1326 pKa = 10.64 FSIPGGKK1333 pKa = 4.71 THH1335 pKa = 6.87 KK1336 pKa = 8.75 MKK1338 pKa = 11.01 KK1339 pKa = 8.66 MDD1341 pKa = 3.49 VVMLKK1346 pKa = 9.78 IQGKK1350 pKa = 7.28 WIKK1353 pKa = 9.26 STIVGFDD1360 pKa = 3.23 RR1361 pKa = 11.84 NNPVLDD1367 pKa = 3.69 YY1368 pKa = 11.33 VAVCEE1373 pKa = 4.19 QRR1375 pKa = 11.84 ASLVEE1380 pKa = 4.28 LKK1382 pKa = 10.62 EE1383 pKa = 4.35 SMGSQIRR1390 pKa = 11.84 EE1391 pKa = 4.08 LVGLCQSYY1399 pKa = 11.41 VDD1401 pKa = 5.06 LKK1403 pKa = 9.57 TLKK1406 pKa = 10.72 SKK1408 pKa = 10.55 LAEE1411 pKa = 4.3 AKK1413 pKa = 10.35 FLTGPAGFGKK1423 pKa = 8.27 STKK1426 pKa = 9.38 IGQSAVPGDD1435 pKa = 4.03 LCVAMTTSAVKK1446 pKa = 10.31 ALQEE1450 pKa = 3.98 KK1451 pKa = 7.36 VTRR1454 pKa = 11.84 GVKK1457 pKa = 10.36 VMTLEE1462 pKa = 4.02 RR1463 pKa = 11.84 ALYY1466 pKa = 9.49 SHH1468 pKa = 7.25 AKK1470 pKa = 8.42 TGQTLFVDD1478 pKa = 4.53 EE1479 pKa = 4.32 ATMVNWLFLGHH1490 pKa = 7.76 LITDD1494 pKa = 3.48 QSRR1497 pKa = 11.84 IEE1499 pKa = 4.2 LFGAEE1504 pKa = 3.99 NQIGKK1509 pKa = 9.62 RR1510 pKa = 11.84 DD1511 pKa = 3.62 MSKK1514 pKa = 9.14 TPGIRR1519 pKa = 11.84 YY1520 pKa = 9.53 NITLSDD1526 pKa = 3.71 FVKK1529 pKa = 10.48 PEE1531 pKa = 3.82 NKK1533 pKa = 8.47 ITEE1536 pKa = 3.99 HH1537 pKa = 4.53 HH1538 pKa = 6.71 TYY1540 pKa = 10.59 RR1541 pKa = 11.84 IGEE1544 pKa = 4.19 PLVTLLRR1551 pKa = 11.84 SVEE1554 pKa = 4.1 PKK1556 pKa = 10.92 LMTKK1560 pKa = 10.51 ASHH1563 pKa = 5.71 KK1564 pKa = 6.03 TTYY1567 pKa = 9.91 TITVLDD1573 pKa = 3.86 PAMVEE1578 pKa = 4.08 NINNIVKK1585 pKa = 10.02 DD1586 pKa = 4.08 RR1587 pKa = 11.84 KK1588 pKa = 9.64 PEE1590 pKa = 4.1 VIITPYY1596 pKa = 10.37 SYY1598 pKa = 11.22 NRR1600 pKa = 11.84 NLIEE1604 pKa = 4.08 QFLKK1608 pKa = 10.55 HH1609 pKa = 5.68 EE1610 pKa = 4.37 RR1611 pKa = 11.84 VPVVTTHH1618 pKa = 7.28 AYY1620 pKa = 9.72 QGVEE1624 pKa = 4.06 VSRR1627 pKa = 11.84 SMVVLKK1633 pKa = 10.8 ADD1635 pKa = 3.81 AGNRR1639 pKa = 11.84 WDD1641 pKa = 4.78 LNGHH1645 pKa = 5.79 PEE1647 pKa = 4.13 YY1648 pKa = 11.04 LNSALTRR1655 pKa = 11.84 AKK1657 pKa = 9.96 YY1658 pKa = 10.11 HH1659 pKa = 5.98 VDD1661 pKa = 3.31 IIIYY1665 pKa = 10.51 GNYY1668 pKa = 9.06 TDD1670 pKa = 4.47 VKK1672 pKa = 9.7 SLEE1675 pKa = 5.04 DD1676 pKa = 3.18 IMTQVGGMDD1685 pKa = 3.78 YY1686 pKa = 10.98 EE1687 pKa = 4.09 YY1688 pKa = 10.95 LQYY1691 pKa = 10.79 FNEE1694 pKa = 4.62 NIEE1697 pKa = 4.3 SATTEE1702 pKa = 3.77 IAEE1705 pKa = 4.28 VNQSNEE1711 pKa = 4.03 TNKK1714 pKa = 10.35 GDD1716 pKa = 4.27 KK1717 pKa = 9.62 LTLKK1721 pKa = 9.81 TGTALPDD1728 pKa = 3.59 VITINTMHH1736 pKa = 6.94 EE1737 pKa = 4.13 LSEE1740 pKa = 4.25 EE1741 pKa = 4.11 MVNQLNEE1748 pKa = 4.48 LNISMQGAKK1757 pKa = 8.62 LTYY1760 pKa = 9.57 QKK1762 pKa = 10.67 LHH1764 pKa = 6.88 EE1765 pKa = 4.77 GTSVTTQFAGATVSKK1780 pKa = 8.95 VTNINGIVNVDD1791 pKa = 3.7 ANPIIKK1797 pKa = 10.19 SKK1799 pKa = 10.49 IMQNLDD1805 pKa = 3.28 TPIDD1809 pKa = 3.7 VPEE1812 pKa = 4.85 LIKK1815 pKa = 10.8 EE1816 pKa = 4.17 QVDD1819 pKa = 3.86 GKK1821 pKa = 10.32 SQSIEE1826 pKa = 3.85 CKK1828 pKa = 7.72 MTLRR1832 pKa = 11.84 QTNKK1836 pKa = 9.11 IRR1838 pKa = 11.84 EE1839 pKa = 4.4 LTWILDD1845 pKa = 3.5 KK1846 pKa = 11.27 TIDD1849 pKa = 4.11 RR1850 pKa = 11.84 EE1851 pKa = 4.46 LKK1853 pKa = 9.37 CTINGVNIKK1862 pKa = 6.77 MTKK1865 pKa = 8.7 TASCPLFAGVTFEE1878 pKa = 4.34 TDD1880 pKa = 3.22 TEE1882 pKa = 4.26 KK1883 pKa = 10.72 LTVSNGWYY1891 pKa = 9.75 HH1892 pKa = 4.07 VTNRR1896 pKa = 11.84 KK1897 pKa = 6.59 VTINKK1902 pKa = 8.72 EE1903 pKa = 3.56 RR1904 pKa = 11.84 FYY1906 pKa = 10.88 PGLTPIIRR1914 pKa = 11.84 WLQLDD1919 pKa = 3.69 IKK1921 pKa = 10.55 EE1922 pKa = 5.23 LILDD1926 pKa = 3.83 SNTNIGWLQVLKK1938 pKa = 11.04 GDD1940 pKa = 3.72 MAHH1943 pKa = 7.05 FLWQLKK1949 pKa = 9.19 EE1950 pKa = 3.91 RR1951 pKa = 11.84 ATQVHH1956 pKa = 6.57 LWLLNFLTEE1965 pKa = 4.12 TDD1967 pKa = 3.92 SPKK1970 pKa = 10.42 CYY1972 pKa = 10.33 YY1973 pKa = 11.15 NNIINTAKK1981 pKa = 9.85 YY1982 pKa = 9.54 NKK1984 pKa = 9.44 AARR1987 pKa = 11.84 SINQPMVTNHH1997 pKa = 6.69 PSVADD2002 pKa = 3.52 HH2003 pKa = 6.8 LNYY2006 pKa = 9.87 IIKK2009 pKa = 9.32 KK2010 pKa = 8.09 QSWIKK2015 pKa = 10.78 KK2016 pKa = 7.55 HH2017 pKa = 5.67 DD2018 pKa = 3.66 TYY2020 pKa = 11.45 ILTNGNQVIIDD2031 pKa = 3.41 ITSNEE2036 pKa = 4.17 EE2037 pKa = 3.49 EE2038 pKa = 4.29 AKK2040 pKa = 9.89 WEE2042 pKa = 3.97 IFAVEE2047 pKa = 4.48 CLADD2051 pKa = 3.69 MVKK2054 pKa = 9.73 TGTGMQGIAAAEE2066 pKa = 3.82 LDD2068 pKa = 4.09 IPGLMIPLHH2077 pKa = 5.86 KK2078 pKa = 10.19 HH2079 pKa = 4.93 LALGTTVQTIINNNLLNLNKK2099 pKa = 8.33 QTRR2102 pKa = 11.84 PGVYY2106 pKa = 9.99 DD2107 pKa = 3.79 VIRR2110 pKa = 11.84 LDD2112 pKa = 3.51 KK2113 pKa = 10.93 QNYY2116 pKa = 8.98 AMQKK2120 pKa = 9.02 HH2121 pKa = 5.08 YY2122 pKa = 10.85 LKK2124 pKa = 10.47 HH2125 pKa = 6.61 RR2126 pKa = 11.84 YY2127 pKa = 8.52 PRR2129 pKa = 11.84 MTITSGNYY2137 pKa = 9.28 EE2138 pKa = 4.4 IINSGIEE2145 pKa = 3.77 LALEE2149 pKa = 3.94 QILLNMRR2156 pKa = 11.84 GGLTEE2161 pKa = 3.94 NSTGIVAYY2169 pKa = 10.49 CGLCPISICMTGKK2182 pKa = 10.33 YY2183 pKa = 9.35 YY2184 pKa = 10.22 IKK2186 pKa = 10.34 IVLPDD2191 pKa = 3.45 VNSNIRR2197 pKa = 11.84 FMYY2200 pKa = 10.54 DD2201 pKa = 3.03 MQKK2204 pKa = 10.21 PQIDD2208 pKa = 3.74 SMLDD2212 pKa = 3.07 NFNAKK2217 pKa = 9.37 RR2218 pKa = 11.84 DD2219 pKa = 4.03 AKK2221 pKa = 10.36 TEE2223 pKa = 4.26 LYY2225 pKa = 9.23 WDD2227 pKa = 4.47 HH2228 pKa = 5.81 EE2229 pKa = 4.96 TKK2231 pKa = 10.61 CEE2233 pKa = 4.12 RR2234 pKa = 11.84 ILAGTSIYY2242 pKa = 11.01 SLTLEE2247 pKa = 4.66 EE2248 pKa = 5.38 ILYY2251 pKa = 10.81 LLDD2254 pKa = 4.82 KK2255 pKa = 9.93 AHH2257 pKa = 6.94 CMYY2260 pKa = 11.13 GWIPTFARR2268 pKa = 11.84 DD2269 pKa = 3.25 TDD2271 pKa = 3.67 EE2272 pKa = 4.21 YY2273 pKa = 11.45 VYY2275 pKa = 10.94 DD2276 pKa = 3.92 RR2277 pKa = 11.84 QLYY2280 pKa = 8.64 CYY2282 pKa = 9.0 GYY2284 pKa = 10.18 RR2285 pKa = 11.84 GGRR2288 pKa = 11.84 VTNKK2292 pKa = 9.17 IRR2294 pKa = 11.84 NDD2296 pKa = 3.53 IIDD2299 pKa = 4.0 KK2300 pKa = 9.91 VNKK2303 pKa = 10.17 GEE2305 pKa = 4.72 PILIKK2310 pKa = 10.23 YY2311 pKa = 8.65 DD2312 pKa = 3.27 KK2313 pKa = 11.14 NEE2315 pKa = 3.92 YY2316 pKa = 10.73 LEE2318 pKa = 4.35 ATVVTEE2324 pKa = 4.08 VFNHH2328 pKa = 6.41 RR2329 pKa = 11.84 LIKK2332 pKa = 10.61 LQFKK2336 pKa = 9.28 PIPVCNYY2343 pKa = 7.85 IDD2345 pKa = 3.88 RR2346 pKa = 11.84 RR2347 pKa = 11.84 LGTYY2351 pKa = 9.15 MDD2353 pKa = 3.99 INNIIKK2359 pKa = 10.22 IKK2361 pKa = 10.46 IPWIDD2366 pKa = 3.51 LDD2368 pKa = 3.94 LFRR2371 pKa = 11.84 VLKK2374 pKa = 10.25 DD2375 pKa = 3.4 RR2376 pKa = 11.84 QIITIKK2382 pKa = 10.38 EE2383 pKa = 3.66 LTINKK2388 pKa = 9.35 RR2389 pKa = 11.84 FLRR2392 pKa = 11.84 NILLRR2397 pKa = 11.84 LMTGDD2402 pKa = 4.02 DD2403 pKa = 3.93 TPHH2406 pKa = 6.94 GALEE2410 pKa = 4.02 YY2411 pKa = 10.88 AKK2413 pKa = 9.24 TLEE2416 pKa = 4.12 STQVITEE2423 pKa = 4.1 KK2424 pKa = 11.13 GIDD2427 pKa = 4.22 DD2428 pKa = 4.07 LTASNLLVTLNTTWYY2443 pKa = 10.5 AIYY2446 pKa = 10.13 IHH2448 pKa = 6.53 NNYY2451 pKa = 9.81 LEE2453 pKa = 4.14 KK2454 pKa = 10.66 FKK2456 pKa = 10.62 TLIHH2460 pKa = 5.95 YY2461 pKa = 9.83 LNYY2464 pKa = 9.53 TDD2466 pKa = 4.04 GRR2468 pKa = 11.84 PVAVLMLEE2476 pKa = 4.21 QILTGIGNLMGMVSDD2491 pKa = 4.09 KK2492 pKa = 11.14 VSDD2495 pKa = 3.26 IAEE2498 pKa = 3.98 QFITYY2503 pKa = 10.3 LNKK2506 pKa = 10.5 NYY2508 pKa = 10.71 NLTNKK2513 pKa = 9.27 MADD2516 pKa = 4.0 CIRR2519 pKa = 11.84 EE2520 pKa = 4.14 AEE2522 pKa = 4.29 KK2523 pKa = 10.66 TNWTPEE2529 pKa = 3.83 TKK2531 pKa = 9.56 QVYY2534 pKa = 9.65 FNRR2537 pKa = 11.84 FYY2539 pKa = 10.92 FSKK2542 pKa = 10.75 DD2543 pKa = 3.12 DD2544 pKa = 3.82 EE2545 pKa = 4.54 FTLRR2549 pKa = 11.84 SWMTGDD2555 pKa = 5.45 DD2556 pKa = 4.76 DD2557 pKa = 6.54 NNDD2560 pKa = 4.01 DD2561 pKa = 5.84 DD2562 pKa = 6.56 DD2563 pKa = 5.87 DD2564 pKa = 5.68 AGKK2567 pKa = 10.49 DD2568 pKa = 3.63 DD2569 pKa = 6.28 DD2570 pKa = 6.32 NVTEE2574 pKa = 4.83 DD2575 pKa = 3.82 NNDD2578 pKa = 3.53 IITTDD2583 pKa = 3.43 STSLPNIGYY2592 pKa = 7.72 EE2593 pKa = 4.81 GPGTSANAEE2602 pKa = 4.08 DD2603 pKa = 4.52 VGTSTTEE2610 pKa = 3.89 LQEE2613 pKa = 4.5 SSTSTTTNDD2622 pKa = 2.77 SDD2624 pKa = 3.92 DD2625 pKa = 4.82 RR2626 pKa = 11.84 IRR2628 pKa = 11.84 KK2629 pKa = 9.37 LMIQPGKK2636 pKa = 9.29 PYY2638 pKa = 10.77 KK2639 pKa = 9.42 NTRR2642 pKa = 11.84 LPIQVMRR2649 pKa = 11.84 FVDD2652 pKa = 3.93 EE2653 pKa = 4.44 KK2654 pKa = 10.63 GATIISRR2661 pKa = 11.84 KK2662 pKa = 5.79 QTIGVLKK2669 pKa = 9.49 TLQLYY2674 pKa = 11.13 GDD2676 pKa = 4.14 FNEE2679 pKa = 4.31 EE2680 pKa = 3.82 QLIKK2684 pKa = 10.28 AAKK2687 pKa = 10.16 LIDD2690 pKa = 4.1 EE2691 pKa = 5.45 DD2692 pKa = 5.21 YY2693 pKa = 10.39 MVHH2696 pKa = 7.34 RR2697 pKa = 11.84 DD2698 pKa = 3.8 LLHH2701 pKa = 6.93 APWNLKK2707 pKa = 8.1 TLSAKK2712 pKa = 10.46 VEE2714 pKa = 4.15 DD2715 pKa = 4.11 ALGVSLEE2722 pKa = 3.93 RR2723 pKa = 11.84 KK2724 pKa = 9.51 YY2725 pKa = 11.21 NEE2727 pKa = 4.47 EE2728 pKa = 4.04 EE2729 pKa = 3.72 PSKK2732 pKa = 11.38 YY2733 pKa = 10.51 NIQLYY2738 pKa = 9.56 SASSGRR2744 pKa = 11.84 DD2745 pKa = 2.99 INISYY2750 pKa = 9.96 SEE2752 pKa = 4.42 HH2753 pKa = 7.1 FMIPKK2758 pKa = 9.91 IIWFYY2763 pKa = 8.45 WHH2765 pKa = 6.24 EE2766 pKa = 4.14 TSVPEE2771 pKa = 5.61 LIMRR2775 pKa = 11.84 CINSWATFNDD2785 pKa = 3.25 SYY2787 pKa = 10.98 MIVVLTKK2794 pKa = 10.32 QEE2796 pKa = 4.0 LSQLIPKK2803 pKa = 9.62 EE2804 pKa = 3.54 ITDD2807 pKa = 3.77 YY2808 pKa = 11.72 VEE2810 pKa = 3.67 NTTPQFASDD2819 pKa = 3.28 WVRR2822 pKa = 11.84 TFVLSRR2828 pKa = 11.84 FGGVWADD2835 pKa = 3.41 ASIICTGTIDD2845 pKa = 3.82 RR2846 pKa = 11.84 LVEE2849 pKa = 3.79 RR2850 pKa = 11.84 TLQNTIGLLQISLGSKK2866 pKa = 6.89 QVKK2869 pKa = 9.8 IKK2871 pKa = 10.08 TSEE2874 pKa = 3.4 NWFIISSTYY2883 pKa = 10.88 NPIITMWNNILTDD2896 pKa = 3.77 LMKK2899 pKa = 9.67 EE2900 pKa = 4.3 TKK2902 pKa = 9.84 PSGEE2906 pKa = 4.22 GCSVWIKK2913 pKa = 10.63 KK2914 pKa = 9.77 KK2915 pKa = 10.9 YY2916 pKa = 7.88 PSEE2919 pKa = 3.82 YY2920 pKa = 10.9 SKK2922 pKa = 9.41 ITKK2925 pKa = 8.99 TMAADD2930 pKa = 3.26 SVDD2933 pKa = 3.57 YY2934 pKa = 10.83 LRR2936 pKa = 11.84 SYY2938 pKa = 10.42 VLEE2941 pKa = 4.68 SIVSQITGLFPEE2953 pKa = 5.48 TICKK2957 pKa = 10.49 DD2958 pKa = 3.25 EE2959 pKa = 4.47 GQLTTFDD2966 pKa = 5.2 DD2967 pKa = 4.88 LPHH2970 pKa = 6.68 SNWDD2974 pKa = 3.72 TLLDD2978 pKa = 3.63 QYY2980 pKa = 7.38 TTKK2983 pKa = 10.36 TKK2985 pKa = 10.56 RR2986 pKa = 11.84 PDD2988 pKa = 3.77 LIIPLVKK2995 pKa = 10.08 MIDD2998 pKa = 3.22 SHH3000 pKa = 8.5 RR3001 pKa = 11.84 IIITDD3006 pKa = 3.71 ALLDD3010 pKa = 4.62 GIKK3013 pKa = 10.41 PEE3015 pKa = 4.35 TGSLLHH3021 pKa = 6.97 EE3022 pKa = 4.62 IYY3024 pKa = 11.28 GMDD3027 pKa = 4.22 FNLKK3031 pKa = 9.98 LHH3033 pKa = 6.41 TLQQVQEE3040 pKa = 4.12 RR3041 pKa = 11.84 LSRR3044 pKa = 11.84 AIKK3047 pKa = 10.55 EE3048 pKa = 3.96 NFEE3051 pKa = 4.05 PVKK3054 pKa = 10.87 KK3055 pKa = 10.38 EE3056 pKa = 3.82 FEE3058 pKa = 4.32 LTRR3061 pKa = 11.84 GLQIFKK3067 pKa = 10.16 TEE3069 pKa = 4.23 FSYY3072 pKa = 11.25 GMAKK3076 pKa = 8.42 LTSMLNNSMTVQEE3089 pKa = 4.2 IQMVRR3094 pKa = 11.84 PALEE3098 pKa = 3.92 FLVKK3102 pKa = 10.3 SGCHH3106 pKa = 5.66 LYY3108 pKa = 8.47 ITEE3111 pKa = 4.12 EE3112 pKa = 4.12 EE3113 pKa = 4.16 LVIMLGMVLGKK3124 pKa = 9.09 MKK3126 pKa = 10.43 HH3127 pKa = 5.27 MKK3129 pKa = 10.04 DD3130 pKa = 3.48 LRR3132 pKa = 11.84 EE3133 pKa = 3.9 EE3134 pKa = 4.01 TQIWVVLEE3142 pKa = 4.99 HH3143 pKa = 6.4 ITDD3146 pKa = 4.07 TKK3148 pKa = 11.07 QIDD3151 pKa = 3.62 LEE3153 pKa = 4.39 KK3154 pKa = 10.24 WFEE3157 pKa = 4.3 TNEE3160 pKa = 4.0 LTTMRR3165 pKa = 11.84 LNVSNRR3171 pKa = 11.84 LPTKK3175 pKa = 9.72 PDD3177 pKa = 3.24 YY3178 pKa = 9.46 VTHH3181 pKa = 6.25 GNRR3184 pKa = 11.84 RR3185 pKa = 11.84 IPKK3188 pKa = 9.4 IVWSYY3193 pKa = 8.25 WDD3195 pKa = 3.38 KK3196 pKa = 11.35 TEE3198 pKa = 3.98 VAEE3201 pKa = 4.91 FQVKK3205 pKa = 9.39 MINNWYY3211 pKa = 9.65 YY3212 pKa = 10.39 HH3213 pKa = 5.19 NQDD3216 pKa = 2.9 YY3217 pKa = 10.92 RR3218 pKa = 11.84 IIILNEE3224 pKa = 3.6 DD3225 pKa = 3.85 TLLKK3229 pKa = 10.08 MVGKK3233 pKa = 8.33 NTHH3236 pKa = 6.46 ALLMRR3241 pKa = 11.84 QTPQFRR3247 pKa = 11.84 SDD3249 pKa = 2.93 WVRR3252 pKa = 11.84 LFILSNFGGVWVDD3265 pKa = 4.24 FSGLFTKK3272 pKa = 10.52 SIHH3275 pKa = 6.08 NLVEE3279 pKa = 4.06 ATVKK3283 pKa = 10.83 NSAGYY3288 pKa = 9.32 CQISLNKK3295 pKa = 9.35 RR3296 pKa = 11.84 TDD3298 pKa = 2.97 KK3299 pKa = 11.15 KK3300 pKa = 10.7 IVLEE3304 pKa = 4.07 SWLIICVEE3312 pKa = 4.03 NCKK3315 pKa = 9.82 TIQSWFDD3322 pKa = 3.13 EE3323 pKa = 4.65 TKK3325 pKa = 10.94 EE3326 pKa = 3.76 MTKK3329 pKa = 10.49 FVDD3332 pKa = 3.77 PSGYY3336 pKa = 10.15 NALEE3340 pKa = 4.31 WMTSTYY3346 pKa = 10.42 GSEE3349 pKa = 3.92 YY3350 pKa = 10.6 QLAKK3354 pKa = 10.59 EE3355 pKa = 4.19 YY3356 pKa = 10.42 ILPNLRR3362 pKa = 11.84 TYY3364 pKa = 10.9 LRR3366 pKa = 11.84 VYY3368 pKa = 9.73 IIQVIVRR3375 pKa = 11.84 LRR3377 pKa = 11.84 VKK3379 pKa = 10.26 DD3380 pKa = 3.91 DD3381 pKa = 3.56 PVIIYY3386 pKa = 10.27 SDD3388 pKa = 3.67 EE3389 pKa = 4.6 ANVSMFHH3396 pKa = 6.35 NLSANAWLNLWDD3408 pKa = 4.13 YY3409 pKa = 11.34 VATKK3413 pKa = 9.89 PKK3415 pKa = 10.57 VEE3417 pKa = 4.22 IDD3419 pKa = 3.34 VGVPFIKK3426 pKa = 10.09 WIGIQRR3432 pKa = 11.84 SIIIEE3437 pKa = 4.05 NYY3439 pKa = 8.81 NCHH3442 pKa = 5.98 HH3443 pKa = 6.87 HH3444 pKa = 6.92 NITPISLLGEE3454 pKa = 4.04 EE3455 pKa = 4.95 LNYY3458 pKa = 10.42 PSITYY3463 pKa = 10.7 NVMSNAEE3470 pKa = 3.87 LTLPNRR3476 pKa = 11.84 EE3477 pKa = 3.58 GSTTKK3482 pKa = 9.26 KK3483 pKa = 8.71 TNNIIINKK3491 pKa = 5.75 YY3492 pKa = 6.6 TNCKK3496 pKa = 8.4 TLLICVGSAGDD3507 pKa = 3.51 VLQFKK3512 pKa = 9.25 TIYY3515 pKa = 10.3 EE3516 pKa = 4.16 IADD3519 pKa = 3.61 SEE3521 pKa = 4.52 GQSPVIITHH3530 pKa = 6.9 KK3531 pKa = 10.53 DD3532 pKa = 2.84 HH3533 pKa = 7.68 SKK3535 pKa = 10.41 YY3536 pKa = 10.59 FEE3538 pKa = 4.24 NKK3540 pKa = 7.6 KK3541 pKa = 10.06 AHH3543 pKa = 5.7 YY3544 pKa = 9.71 FDD3546 pKa = 4.44 VEE3548 pKa = 4.34 SEE3550 pKa = 4.06 EE3551 pKa = 5.29 LMALVNIVLNEE3562 pKa = 3.36 VDD3564 pKa = 3.63 LWMDD3568 pKa = 3.45 IKK3570 pKa = 10.94 ASHH3573 pKa = 7.16 LVRR3576 pKa = 11.84 QISDD3580 pKa = 4.51 DD3581 pKa = 3.01 ITAIARR3587 pKa = 11.84 NYY3589 pKa = 8.08 EE3590 pKa = 3.95 QIIEE3594 pKa = 4.14 KK3595 pKa = 10.59 VIVNSAVPNLTEE3607 pKa = 4.38 LGKK3610 pKa = 9.31 MLPCDD3615 pKa = 3.52 WLEE3618 pKa = 3.91 VSTFTDD3624 pKa = 2.82 NVVFNPKK3631 pKa = 8.46 KK3632 pKa = 7.24 TTGLKK3637 pKa = 10.55 GSILRR3642 pKa = 11.84 AKK3644 pKa = 9.76 EE3645 pKa = 3.88 WLHH3648 pKa = 6.51 HH3649 pKa = 6.18 NIIKK3653 pKa = 10.44 SEE3655 pKa = 4.01 LKK3657 pKa = 10.23 EE3658 pKa = 3.93 EE3659 pKa = 4.25 NVRR3662 pKa = 11.84 SLRR3665 pKa = 11.84 KK3666 pKa = 9.25 FCSGYY3671 pKa = 9.61 PLFYY3675 pKa = 9.67 PYY3677 pKa = 11.1 VMSVCGPLTIWSMPSNHH3694 pKa = 6.14 NEE3696 pKa = 4.02 MIMSEE3701 pKa = 4.1 QDD3703 pKa = 3.27 VLITFGSCDD3712 pKa = 3.21 NTITTKK3718 pKa = 10.89 SKK3720 pKa = 10.55 IKK3722 pKa = 10.45 LIEE3725 pKa = 3.82 NFIDD3729 pKa = 3.25 CGYY3732 pKa = 10.56 RR3733 pKa = 11.84 VTYY3736 pKa = 9.11 HH3737 pKa = 7.45 DD3738 pKa = 4.89 KK3739 pKa = 11.07 YY3740 pKa = 10.95 QIAVPGSVLFNAMEE3754 pKa = 4.0 QYY3756 pKa = 9.73 PGKK3759 pKa = 10.53 FGIVNNYY3766 pKa = 8.69 DD3767 pKa = 3.21 LRR3769 pKa = 11.84 SVKK3772 pKa = 10.17 GGKK3775 pKa = 8.96 FVLVTHH3781 pKa = 7.04 GGHH3784 pKa = 5.05 GTIMEE3789 pKa = 4.68 ALLTNCKK3796 pKa = 10.02 IMIHH3800 pKa = 6.64 PIIADD3805 pKa = 3.35 QFSICDD3811 pKa = 3.38 TMVQQRR3817 pKa = 11.84 MAVKK3821 pKa = 9.09 LTDD3824 pKa = 3.17 ITNVNDD3830 pKa = 3.33 CRR3832 pKa = 11.84 QAIAGLNRR3840 pKa = 11.84 LIDD3843 pKa = 3.31 TTLAVKK3849 pKa = 9.8 PVISVFFKK3857 pKa = 10.95 PLIFWLKK3864 pKa = 9.85 PEE3866 pKa = 4.19 YY3867 pKa = 10.68 KK3868 pKa = 9.29 IDD3870 pKa = 4.47 SPDD3873 pKa = 3.35 EE3874 pKa = 3.92 TLKK3877 pKa = 10.92 ILDD3880 pKa = 4.27 DD3881 pKa = 4.37 AEE3883 pKa = 4.56 VMGDD3887 pKa = 3.56 YY3888 pKa = 11.2 DD3889 pKa = 3.9 NVGSGIYY3896 pKa = 9.91 RR3897 pKa = 11.84 ILDD3900 pKa = 3.35 VEE3902 pKa = 4.25 HH3903 pKa = 6.76 QILYY3907 pKa = 10.36 DD3908 pKa = 3.51 PQVPNRR3914 pKa = 11.84 CVTHH3918 pKa = 6.55 SLEE3921 pKa = 4.24 YY3922 pKa = 9.44 MLQGSGQEE3930 pKa = 4.97 KK3931 pKa = 10.55 YY3932 pKa = 9.11 LTCNTIAVMRR3942 pKa = 11.84 LQQHH3946 pKa = 5.54 SVTEE3950 pKa = 3.92 QEE3952 pKa = 5.06 LIDD3955 pKa = 4.34 GVLSMGVNVILVYY3968 pKa = 11.21 SNGTGLVVKK3977 pKa = 9.09 TMNGPTMCFYY3987 pKa = 11.21 VDD3989 pKa = 3.66 RR3990 pKa = 11.84 SRR3992 pKa = 11.84 TPWHH3996 pKa = 5.52 VCAARR4001 pKa = 11.84 LVKK4004 pKa = 10.42 HH4005 pKa = 6.13 GEE4007 pKa = 4.18 VIDD4010 pKa = 3.98 LMKK4013 pKa = 10.69 RR4014 pKa = 11.84 NAFIRR4019 pKa = 11.84 EE4020 pKa = 4.22 LPHH4023 pKa = 8.49 SIDD4026 pKa = 3.52 YY4027 pKa = 9.68 EE4028 pKa = 4.11 INEE4031 pKa = 3.95 LHH4033 pKa = 6.83 KK4034 pKa = 11.1 NFSTAMLCIPKK4045 pKa = 10.48 LMAQQFGKK4053 pKa = 10.72 SFFKK4057 pKa = 11.1 NFLARR4062 pKa = 11.84 TKK4064 pKa = 9.62 STNLQVLSSRR4074 pKa = 11.84 TDD4076 pKa = 2.96 LHH4078 pKa = 5.99 VAYY4081 pKa = 8.61 ITIKK4085 pKa = 9.61 QHH4087 pKa = 5.08 FDD4089 pKa = 2.26 AWIGDD4094 pKa = 4.11 TIYY4097 pKa = 10.53 PDD4099 pKa = 3.5 TPLGVGWVITAQGWVLANYY4118 pKa = 8.54 FIKK4121 pKa = 10.8 DD4122 pKa = 3.57 GIIVVFSDD4130 pKa = 5.19 DD4131 pKa = 4.59 GILEE4135 pKa = 3.96 QTILINLHH4143 pKa = 5.09 LQYY4146 pKa = 10.39 PVEE4149 pKa = 4.04 RR4150 pKa = 11.84 SKK4152 pKa = 11.51 SVILSTKK4159 pKa = 10.24 QEE4161 pKa = 4.13 LVSLNKK4167 pKa = 8.32 PTIMYY4172 pKa = 7.45 TTLNHH4177 pKa = 5.87 CVPRR4181 pKa = 11.84 SSNLVSNFHH4190 pKa = 6.35 KK4191 pKa = 10.88 QNILIVADD4199 pKa = 3.99 FDD4201 pKa = 3.9 NRR4203 pKa = 11.84 KK4204 pKa = 8.75 HH4205 pKa = 7.18 HH4206 pKa = 6.46 MFDD4209 pKa = 3.12 EE4210 pKa = 4.11 MDD4212 pKa = 3.83 MIKK4215 pKa = 10.29 RR4216 pKa = 11.84 AAKK4219 pKa = 10.43 VIFHH4223 pKa = 6.26 TNKK4226 pKa = 9.72 QIKK4229 pKa = 9.9 VEE4231 pKa = 4.25 DD4232 pKa = 3.79 LASSHH4237 pKa = 6.03 NAPLNRR4243 pKa = 11.84 MVIKK4247 pKa = 10.06 QGKK4250 pKa = 8.03 VLYY4253 pKa = 9.6 EE4254 pKa = 3.98 HH4255 pKa = 6.86 EE4256 pKa = 4.85 FEE4258 pKa = 4.12 EE4259 pKa = 5.58 KK4260 pKa = 8.74 MRR4262 pKa = 11.84 QRR4264 pKa = 11.84 QVVKK4268 pKa = 10.79 LFGLNVMSEE4277 pKa = 4.29 QQCITASPLTEE4288 pKa = 3.73 EE4289 pKa = 4.37 QINYY4293 pKa = 8.11 IYY4295 pKa = 10.63 KK4296 pKa = 10.31 YY4297 pKa = 10.21 FVKK4300 pKa = 10.55 SGNKK4304 pKa = 9.14 LVAIDD4309 pKa = 3.7 NEE4311 pKa = 4.61 SYY4313 pKa = 10.79 NDD4315 pKa = 3.91 KK4316 pKa = 10.44 EE4317 pKa = 4.48 IKK4319 pKa = 10.09 PSDD4322 pKa = 3.27 WVITLIQNSEE4332 pKa = 4.0 VMSNDD4337 pKa = 3.44 VINNLIKK4344 pKa = 10.42 LVKK4347 pKa = 8.82 EE4348 pKa = 3.52 HH4349 pKa = 6.56 SMWHH4353 pKa = 6.88 IYY4355 pKa = 9.17 DD4356 pKa = 3.24 QHH4358 pKa = 8.02 NYY4360 pKa = 8.43 EE4361 pKa = 5.07 LSMTQAGDD4369 pKa = 3.67 VVTLEE4374 pKa = 5.59 HH4375 pKa = 6.74 GDD4377 pKa = 3.71 LWVKK4381 pKa = 10.57 SYY4383 pKa = 11.33 GIVLVYY4389 pKa = 10.44 VRR4391 pKa = 11.84 VGGQRR4396 pKa = 11.84 EE4397 pKa = 4.02 RR4398 pKa = 11.84 LSWKK4402 pKa = 10.24 LDD4404 pKa = 3.29 TDD4406 pKa = 3.81 SAQINNPKK4414 pKa = 9.99 PGDD4417 pKa = 2.95 WWGLEE4422 pKa = 4.04 TKK4424 pKa = 8.9 TQTKK4428 pKa = 10.27 VNSNFKK4434 pKa = 10.53 NVLAINEE4441 pKa = 4.31 LKK4443 pKa = 10.3 YY4444 pKa = 10.66 HH4445 pKa = 5.78 EE4446 pKa = 5.32 PEE4448 pKa = 3.94 TLLVDD4453 pKa = 3.92 GSNVVEE4459 pKa = 5.02 SDD4461 pKa = 4.5 DD4462 pKa = 4.63 LLDD4465 pKa = 3.96 MYY4467 pKa = 10.61 IPPYY4471 pKa = 9.95 HH4472 pKa = 6.41 YY4473 pKa = 10.22 GYY4475 pKa = 8.28 TGSVIEE4481 pKa = 4.82 PLLDD4485 pKa = 4.04 FPDD4488 pKa = 4.65 NIAMQLWEE4496 pKa = 5.15 DD4497 pKa = 3.75 TDD4499 pKa = 3.71 QTDD4502 pKa = 3.3 WLSLYY4507 pKa = 10.64 APSNQCQLKK4516 pKa = 10.37 SRR4518 pKa = 11.84 EE4519 pKa = 4.18 LPGKK4523 pKa = 10.09 IIQTEE4528 pKa = 4.5 KK4529 pKa = 9.44 ITLTKK4534 pKa = 9.67 WPIRR4538 pKa = 11.84 SRR4540 pKa = 11.84 AVLTKK4545 pKa = 9.98 VCFEE4549 pKa = 4.37 EE4550 pKa = 5.04 GRR4552 pKa = 11.84 SILGRR4557 pKa = 11.84 MKK4559 pKa = 10.14 SVAFIRR4565 pKa = 11.84 TVTPDD4570 pKa = 3.39 PYY4572 pKa = 11.24 KK4573 pKa = 10.87 LVMDD4577 pKa = 4.06 MADD4580 pKa = 3.12 TYY4582 pKa = 10.77 FIKK4585 pKa = 10.68 GWVTKK4590 pKa = 10.65 VNEE4593 pKa = 4.01 FRR4595 pKa = 11.84 AKK4597 pKa = 10.25 RR4598 pKa = 11.84 LVILPEE4604 pKa = 4.04 DD4605 pKa = 3.53 VKK4607 pKa = 11.09 RR4608 pKa = 11.84 WVEE4611 pKa = 3.96 TNKK4614 pKa = 9.98 DD4615 pKa = 3.28 AKK4617 pKa = 10.57 RR4618 pKa = 11.84 IEE4620 pKa = 4.31 PEE4622 pKa = 3.91 LLEE4625 pKa = 4.38 LLSGEE4630 pKa = 4.16 ILVKK4634 pKa = 10.52 PMNDD4638 pKa = 3.08 VNIHH4642 pKa = 6.41 LKK4644 pKa = 10.85 LEE4646 pKa = 4.24 SLLKK4650 pKa = 11.01 DD4651 pKa = 3.16 NTTIMTKK4658 pKa = 8.07 QQQARR4663 pKa = 11.84 IIVWQRR4669 pKa = 11.84 KK4670 pKa = 7.41 AVCAIYY4676 pKa = 10.95 SNLFVKK4682 pKa = 10.76 VKK4684 pKa = 10.75 DD4685 pKa = 3.62 RR4686 pKa = 11.84 LKK4688 pKa = 11.0 SILHH4692 pKa = 6.45 DD4693 pKa = 4.52 KK4694 pKa = 10.5 IIYY4697 pKa = 10.32 ADD4699 pKa = 3.68 GLRR4702 pKa = 11.84 PDD4704 pKa = 4.57 EE4705 pKa = 3.95 ISARR4709 pKa = 11.84 VRR4711 pKa = 11.84 LCKK4714 pKa = 10.5 DD4715 pKa = 2.48 IAGFFEE4721 pKa = 5.17 NDD4723 pKa = 2.82 LTKK4726 pKa = 10.25 QDD4728 pKa = 3.96 RR4729 pKa = 11.84 QTDD4732 pKa = 3.65 APIITTEE4739 pKa = 3.59 MYY4741 pKa = 9.69 MYY4743 pKa = 10.73 DD4744 pKa = 3.84 LLGVHH4749 pKa = 6.84 PNVIASWRR4757 pKa = 11.84 EE4758 pKa = 3.5 MHH4760 pKa = 6.21 EE4761 pKa = 3.75 VWRR4764 pKa = 11.84 FKK4766 pKa = 11.19 SNHH4769 pKa = 5.05 YY4770 pKa = 8.83 WGQGQGMRR4778 pKa = 11.84 LTGQATTAIGNCITNLQVHH4797 pKa = 5.24 QEE4799 pKa = 4.06 FVKK4802 pKa = 10.92 KK4803 pKa = 10.42 NFSILEE4809 pKa = 4.03 LALFLGDD4816 pKa = 3.87 DD4817 pKa = 3.26 MCMVFRR4823 pKa = 11.84 EE4824 pKa = 4.3 KK4825 pKa = 10.64 PDD4827 pKa = 3.5 TKK4829 pKa = 10.93 NLRR4832 pKa = 11.84 KK4833 pKa = 10.3 NIATKK4838 pKa = 10.73 FNMQSKK4844 pKa = 9.79 DD4845 pKa = 2.44 AWYY4848 pKa = 10.5 RR4849 pKa = 11.84 NGATFCSMVMSRR4861 pKa = 11.84 TPTGAEE4867 pKa = 3.73 LCPDD4871 pKa = 3.65 VVRR4874 pKa = 11.84 LKK4876 pKa = 10.62 FRR4878 pKa = 11.84 YY4879 pKa = 8.49 EE4880 pKa = 3.97 VTNGVHH4886 pKa = 6.01 EE4887 pKa = 4.82 ANAEE4891 pKa = 4.1 NILMRR4896 pKa = 11.84 KK4897 pKa = 9.44 ASYY4900 pKa = 11.27 IMMLGEE4906 pKa = 4.38 GPNVKK4911 pKa = 8.59 EE4912 pKa = 4.25 TVTKK4916 pKa = 10.75 LNLPIKK4922 pKa = 9.72 PLVWYY4927 pKa = 9.65 DD4928 pKa = 3.48 FEE4930 pKa = 5.58 SMLRR4934 pKa = 11.84 AVGDD4938 pKa = 3.97 KK4939 pKa = 10.76 YY4940 pKa = 11.69 DD4941 pKa = 3.61 MSHH4944 pKa = 5.54 VQVLDD4949 pKa = 3.32 VYY4951 pKa = 11.34 YY4952 pKa = 11.23 NLLQMLNSEE4961 pKa = 3.98 KK4962 pKa = 10.58 LYY4964 pKa = 10.41 RR4965 pKa = 11.84 HH4966 pKa = 5.98 TFRR4969 pKa = 11.84 HH4970 pKa = 5.82 FSNIEE4975 pKa = 3.66 GKK4977 pKa = 10.26
Molecular weight: 572.58 kDa
Isoelectric point according different methods:
IPC2.protein.svr19 6.025
IPC2_protein 6.02
IPC_protein 6.084
Toseland 6.44
ProMoST 6.491
Dawson 6.402
Bjellqvist 6.415
Wikipedia 6.415
Rodwell 6.389
Grimsley 6.59
Solomon 6.402
Lehninger 6.402
Nozaki 6.693
DTASelect 6.868
Thurlkill 6.883
EMBOSS 6.854
Sillero 6.781
Patrickios 4.151
IPC_peptide 6.415
IPC2_peptide 6.664
IPC2.peptide.svr19 6.711
Peptides (in silico digests for buttom-up proteomics)
Below you can find
in silico digests of the whole proteome with Trypsin, Chymotrypsin, Trypsin+LysC, LysN, ArgC proteases suitable for different mass spec machines.
Try ESI
ChTry ESI
ArgC ESI
LysN ESI
TryLysC ESI
Try MALDI
ChTry MALDI
ArgC MALDI
LysN MALDI
TryLysC MALDI
Try LTQ
ChTry LTQ
ArgC LTQ
LysN LTQ
TryLysC LTQ
Try MSlow
ChTry MSlow
ArgC MSlow
LysN MSlow
TryLysC MSlow
Try MShigh
ChTry MShigh
ArgC MShigh
LysN MShigh
TryLysC MShigh
General Statistics
Number of major isoforms
Number of additional isoforms
Number of all proteins
Number of amino acids
Min. Seq. Length
Max. Seq. Length
Avg. Seq. Length
Avg. Mol. Weight
1
0
1
4977
4977
4977
4977.0
572.58
Amino acid frequency
Ala
Cys
Asp
Glu
Phe
Gly
His
Ile
Lys
Leu
3.978 ± 0.0
1.547 ± 0.0
5.947 ± 0.0
6.47 ± 0.0
3.355 ± 0.0
4.862 ± 0.0
2.733 ± 0.0
8.298 ± 0.0
7.414 ± 0.0
9.363 ± 0.0
Met
Asn
Gln
Pro
Arg
Ser
Thr
Val
Trp
Tyr
3.114 ± 0.0
6.57 ± 0.0
3.757 ± 0.0
3.436 ± 0.0
4.179 ± 0.0
5.385 ± 0.0
6.972 ± 0.0
6.852 ± 0.0
1.607 ± 0.0
4.159 ± 0.0
Note: For amino acid frequency statistics the error has been estimated with the bootstraping (x100) at the protein level
Most of the basic statistics you can see at this page can be downloaded from this CSV file
For dipeptide frequency statistics click here