Amino acid dipepetide frequency for Krasilnikoviella flava

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	23.398AlaAla: 23.398 ± 0.235	0.78AlaCys: 0.78 ± 0.022	9.653AlaAsp: 9.653 ± 0.102	8.157AlaGlu: 8.157 ± 0.096	3.567AlaPhe: 3.567 ± 0.06	14.477AlaGly: 14.477 ± 0.127	2.741AlaHis: 2.741 ± 0.049	3.6AlaIle: 3.6 ± 0.054	1.985AlaLys: 1.985 ± 0.046	14.751AlaLeu: 14.751 ± 0.133	2.572AlaMet: 2.572 ± 0.047	1.764AlaAsn: 1.764 ± 0.035	7.905AlaPro: 7.905 ± 0.097	3.799AlaGln: 3.799 ± 0.053	11.486AlaArg: 11.486 ± 0.124	6.503AlaSer: 6.503 ± 0.066	8.555AlaThr: 8.555 ± 0.081	13.861AlaVal: 13.861 ± 0.137	2.338AlaTrp: 2.338 ± 0.044	2.407AlaTyr: 2.407 ± 0.038	0.0AlaXaa: 0.0 ± 0.0
Cys	0.738CysAla: 0.738 ± 0.023	0.052CysCys: 0.052 ± 0.006	0.323CysAsp: 0.323 ± 0.015	0.266CysGlu: 0.266 ± 0.011	0.151CysPhe: 0.151 ± 0.012	0.632CysGly: 0.632 ± 0.023	0.121CysHis: 0.121 ± 0.009	0.095CysIle: 0.095 ± 0.008	0.053CysLys: 0.053 ± 0.006	0.468CysLeu: 0.468 ± 0.018	0.058CysMet: 0.058 ± 0.007	0.073CysAsn: 0.073 ± 0.007	0.316CysPro: 0.316 ± 0.016	0.099CysGln: 0.099 ± 0.009	0.369CysArg: 0.369 ± 0.016	0.298CysSer: 0.298 ± 0.013	0.329CysThr: 0.329 ± 0.019	0.454CysVal: 0.454 ± 0.017	0.074CysTrp: 0.074 ± 0.007	0.089CysTyr: 0.089 ± 0.008	0.0CysXaa: 0.0 ± 0.0
Asp	10.187AspAla: 10.187 ± 0.1	0.245AspCys: 0.245 ± 0.012	5.682AspAsp: 5.682 ± 0.079	4.174AspGlu: 4.174 ± 0.057	1.381AspPhe: 1.381 ± 0.033	7.917AspGly: 7.917 ± 0.101	1.353AspHis: 1.353 ± 0.033	1.264AspIle: 1.264 ± 0.029	0.777AspLys: 0.777 ± 0.028	7.083AspLeu: 7.083 ± 0.073	0.738AspMet: 0.738 ± 0.024	0.725AspAsn: 0.725 ± 0.019	4.991AspPro: 4.991 ± 0.077	1.544AspGln: 1.544 ± 0.032	4.832AspArg: 4.832 ± 0.053	2.017AspSer: 2.017 ± 0.042	2.982AspThr: 2.982 ± 0.051	7.649AspVal: 7.649 ± 0.089	0.95AspTrp: 0.95 ± 0.029	1.121AspTyr: 1.121 ± 0.026	0.0AspXaa: 0.0 ± 0.0
Glu	7.146GluAla: 7.146 ± 0.093	0.237GluCys: 0.237 ± 0.017	2.884GluAsp: 2.884 ± 0.053	2.653GluGlu: 2.653 ± 0.057	1.215GluPhe: 1.215 ± 0.027	4.055GluGly: 4.055 ± 0.058	1.67GluHis: 1.67 ± 0.037	2.084GluIle: 2.084 ± 0.041	1.013GluLys: 1.013 ± 0.03	6.249GluLeu: 6.249 ± 0.064	0.76GluMet: 0.76 ± 0.022	0.93GluAsn: 0.93 ± 0.027	3.547GluPro: 3.547 ± 0.059	2.01GluGln: 2.01 ± 0.041	5.253GluArg: 5.253 ± 0.076	2.255GluSer: 2.255 ± 0.04	2.647GluThr: 2.647 ± 0.045	4.996GluVal: 4.996 ± 0.067	0.684GluTrp: 0.684 ± 0.022	0.964GluTyr: 0.964 ± 0.028	0.0GluXaa: 0.0 ± 0.0
Phe	3.738PheAla: 3.738 ± 0.062	0.17PheCys: 0.17 ± 0.012	1.982PheAsp: 1.982 ± 0.038	1.343PheGlu: 1.343 ± 0.035	0.877PhePhe: 0.877 ± 0.03	2.849PheGly: 2.849 ± 0.048	0.539PheHis: 0.539 ± 0.021	0.566PheIle: 0.566 ± 0.022	0.355PheLys: 0.355 ± 0.018	2.608PheLeu: 2.608 ± 0.058	0.394PheMet: 0.394 ± 0.017	0.472PheAsn: 0.472 ± 0.018	1.288PhePro: 1.288 ± 0.03	0.632PheGln: 0.632 ± 0.022	1.659PheArg: 1.659 ± 0.036	1.413PheSer: 1.413 ± 0.032	1.773PheThr: 1.773 ± 0.043	2.774PheVal: 2.774 ± 0.05	0.484PheTrp: 0.484 ± 0.02	0.584PheTyr: 0.584 ± 0.021	0.0PheXaa: 0.0 ± 0.0
Gly	12.809GlyAla: 12.809 ± 0.12	0.543GlyCys: 0.543 ± 0.02	5.845GlyAsp: 5.845 ± 0.082	4.986GlyGlu: 4.986 ± 0.07	2.903GlyPhe: 2.903 ± 0.047	8.83GlyGly: 8.83 ± 0.098	2.082GlyHis: 2.082 ± 0.041	3.263GlyIle: 3.263 ± 0.058	1.747GlyLys: 1.747 ± 0.044	9.694GlyLeu: 9.694 ± 0.087	1.972GlyMet: 1.972 ± 0.041	1.461GlyAsn: 1.461 ± 0.037	5.206GlyPro: 5.206 ± 0.063	2.381GlyGln: 2.381 ± 0.044	7.56GlyArg: 7.56 ± 0.076	5.261GlySer: 5.261 ± 0.07	6.681GlyThr: 6.681 ± 0.081	8.982GlyVal: 8.982 ± 0.084	1.879GlyTrp: 1.879 ± 0.044	2.216GlyTyr: 2.216 ± 0.043	0.0GlyXaa: 0.0 ± 0.0
His	2.713HisAla: 2.713 ± 0.045	0.103HisCys: 0.103 ± 0.009	1.718HisAsp: 1.718 ± 0.036	1.138HisGlu: 1.138 ± 0.031	0.454HisPhe: 0.454 ± 0.02	2.288HisGly: 2.288 ± 0.04	0.604HisHis: 0.604 ± 0.02	0.359HisIle: 0.359 ± 0.018	0.193HisLys: 0.193 ± 0.011	2.343HisLeu: 2.343 ± 0.045	0.235HisMet: 0.235 ± 0.01	0.291HisAsn: 0.291 ± 0.015	1.597HisPro: 1.597 ± 0.034	0.505HisGln: 0.505 ± 0.017	1.833HisArg: 1.833 ± 0.039	0.738HisSer: 0.738 ± 0.025	0.96HisThr: 0.96 ± 0.027	2.147HisVal: 2.147 ± 0.045	0.318HisTrp: 0.318 ± 0.014	0.4HisTyr: 0.4 ± 0.018	0.0HisXaa: 0.0 ± 0.0
Ile	3.974IleAla: 3.974 ± 0.066	0.157IleCys: 0.157 ± 0.011	2.157IleAsp: 2.157 ± 0.044	1.703IleGlu: 1.703 ± 0.036	0.748IlePhe: 0.748 ± 0.029	2.897IleGly: 2.897 ± 0.05	0.444IleHis: 0.444 ± 0.018	0.751IleIle: 0.751 ± 0.023	0.483IleLys: 0.483 ± 0.019	2.314IleLeu: 2.314 ± 0.051	0.412IleMet: 0.412 ± 0.018	0.493IleAsn: 0.493 ± 0.018	1.488IlePro: 1.488 ± 0.036	0.552IleGln: 0.552 ± 0.019	1.557IleArg: 1.557 ± 0.038	1.357IleSer: 1.357 ± 0.034	1.856IleThr: 1.856 ± 0.042	2.926IleVal: 2.926 ± 0.055	0.329IleTrp: 0.329 ± 0.017	0.454IleTyr: 0.454 ± 0.018	0.0IleXaa: 0.0 ± 0.0
Lys	1.89LysAla: 1.89 ± 0.039	0.055LysCys: 0.055 ± 0.006	0.972LysAsp: 0.972 ± 0.036	0.79LysGlu: 0.79 ± 0.025	0.324LysPhe: 0.324 ± 0.016	1.282LysGly: 1.282 ± 0.034	0.357LysHis: 0.357 ± 0.016	0.591LysIle: 0.591 ± 0.02	0.486LysLys: 0.486 ± 0.024	1.244LysLeu: 1.244 ± 0.034	0.247LysMet: 0.247 ± 0.012	0.351LysAsn: 0.351 ± 0.017	0.866LysPro: 0.866 ± 0.025	0.464LysGln: 0.464 ± 0.018	0.989LysArg: 0.989 ± 0.028	0.761LysSer: 0.761 ± 0.025	0.899LysThr: 0.899 ± 0.027	1.448LysVal: 1.448 ± 0.035	0.156LysTrp: 0.156 ± 0.01	0.314LysTyr: 0.314 ± 0.018	0.0LysXaa: 0.0 ± 0.0
Leu	16.359LeuAla: 16.359 ± 0.148	0.551LeuCys: 0.551 ± 0.02	7.559LeuAsp: 7.559 ± 0.08	5.033LeuGlu: 5.033 ± 0.064	2.465LeuPhe: 2.465 ± 0.054	9.942LeuGly: 9.942 ± 0.089	1.989LeuHis: 1.989 ± 0.037	2.182LeuIle: 2.182 ± 0.051	1.225LeuLys: 1.225 ± 0.028	10.67LeuLeu: 10.67 ± 0.13	1.417LeuMet: 1.417 ± 0.032	1.309LeuAsn: 1.309 ± 0.034	6.026LeuPro: 6.026 ± 0.073	2.228LeuGln: 2.228 ± 0.04	8.114LeuArg: 8.114 ± 0.097	4.628LeuSer: 4.628 ± 0.066	6.264LeuThr: 6.264 ± 0.073	11.165LeuVal: 11.165 ± 0.116	1.361LeuTrp: 1.361 ± 0.037	1.595LeuTyr: 1.595 ± 0.036	0.0LeuXaa: 0.0 ± 0.0
Met	1.951MetAla: 1.951 ± 0.04	0.099MetCys: 0.099 ± 0.009	0.766MetAsp: 0.766 ± 0.024	0.53MetGlu: 0.53 ± 0.02	0.473MetPhe: 0.473 ± 0.021	1.148MetGly: 1.148 ± 0.028	0.324MetHis: 0.324 ± 0.015	0.639MetIle: 0.639 ± 0.025	0.278MetLys: 0.278 ± 0.015	1.662MetLeu: 1.662 ± 0.039	0.24MetMet: 0.24 ± 0.013	0.333MetAsn: 0.333 ± 0.013	1.09MetPro: 1.09 ± 0.026	0.433MetGln: 0.433 ± 0.017	1.201MetArg: 1.201 ± 0.028	1.278MetSer: 1.278 ± 0.025	1.818MetThr: 1.818 ± 0.033	1.333MetVal: 1.333 ± 0.032	0.201MetTrp: 0.201 ± 0.011	0.243MetTyr: 0.243 ± 0.012	0.0MetXaa: 0.0 ± 0.0
Asn	1.838AsnAla: 1.838 ± 0.038	0.074AsnCys: 0.074 ± 0.006	0.91AsnAsp: 0.91 ± 0.028	0.662AsnGlu: 0.662 ± 0.023	0.459AsnPhe: 0.459 ± 0.02	1.423AsnGly: 1.423 ± 0.039	0.313AsnHis: 0.313 ± 0.016	0.455AsnIle: 0.455 ± 0.02	0.245AsnLys: 0.245 ± 0.014	1.564AsnLeu: 1.564 ± 0.032	0.233AsnMet: 0.233 ± 0.013	0.333AsnAsn: 0.333 ± 0.016	1.239AsnPro: 1.239 ± 0.031	0.422AsnGln: 0.422 ± 0.017	0.917AsnArg: 0.917 ± 0.025	0.647AsnSer: 0.647 ± 0.023	0.88AsnThr: 0.88 ± 0.03	1.399AsnVal: 1.399 ± 0.031	0.199AsnTrp: 0.199 ± 0.012	0.398AsnTyr: 0.398 ± 0.018	0.0AsnXaa: 0.0 ± 0.0
Pro	9.203ProAla: 9.203 ± 0.096	0.206ProCys: 0.206 ± 0.012	4.941ProAsp: 4.941 ± 0.066	4.021ProGlu: 4.021 ± 0.054	1.552ProPhe: 1.552 ± 0.037	6.7ProGly: 6.7 ± 0.073	1.245ProHis: 1.245 ± 0.032	1.193ProIle: 1.193 ± 0.029	0.72ProLys: 0.72 ± 0.025	5.044ProLeu: 5.044 ± 0.058	0.884ProMet: 0.884 ± 0.023	0.761ProAsn: 0.761 ± 0.028	3.028ProPro: 3.028 ± 0.057	1.545ProGln: 1.545 ± 0.033	4.103ProArg: 4.103 ± 0.054	3.198ProSer: 3.198 ± 0.059	3.79ProThr: 3.79 ± 0.06	5.94ProVal: 5.94 ± 0.08	0.986ProTrp: 0.986 ± 0.028	1.116ProTyr: 1.116 ± 0.033	0.0ProXaa: 0.0 ± 0.0
Gln	3.474GlnAla: 3.474 ± 0.052	0.103GlnCys: 0.103 ± 0.009	1.403GlnAsp: 1.403 ± 0.033	1.274GlnGlu: 1.274 ± 0.028	0.666GlnPhe: 0.666 ± 0.021	2.159GlnGly: 2.159 ± 0.038	0.629GlnHis: 0.629 ± 0.022	0.882GlnIle: 0.882 ± 0.03	0.447GlnLys: 0.447 ± 0.02	2.576GlnLeu: 2.576 ± 0.041	0.442GlnMet: 0.442 ± 0.017	0.429GlnAsn: 0.429 ± 0.018	1.439GlnPro: 1.439 ± 0.036	1.022GlnGln: 1.022 ± 0.029	2.111GlnArg: 2.111 ± 0.033	1.072GlnSer: 1.072 ± 0.026	1.272GlnThr: 1.272 ± 0.032	2.939GlnVal: 2.939 ± 0.046	0.424GlnTrp: 0.424 ± 0.017	0.542GlnTyr: 0.542 ± 0.021	0.0GlnXaa: 0.0 ± 0.0
Arg	10.535ArgAla: 10.535 ± 0.114	0.347ArgCys: 0.347 ± 0.015	4.82ArgAsp: 4.82 ± 0.063	4.313ArgGlu: 4.313 ± 0.062	2.13ArgPhe: 2.13 ± 0.037	6.082ArgGly: 6.082 ± 0.065	1.795ArgHis: 1.795 ± 0.036	2.353ArgIle: 2.353 ± 0.047	1.111ArgLys: 1.111 ± 0.032	8.131ArgLeu: 8.131 ± 0.078	1.566ArgMet: 1.566 ± 0.035	1.009ArgAsn: 1.009 ± 0.03	4.747ArgPro: 4.747 ± 0.062	1.916ArgGln: 1.916 ± 0.036	7.992ArgArg: 7.992 ± 0.103	4.07ArgSer: 4.07 ± 0.058	5.228ArgThr: 5.228 ± 0.06	6.961ArgVal: 6.961 ± 0.083	1.557ArgTrp: 1.557 ± 0.039	1.673ArgTyr: 1.673 ± 0.032	0.0ArgXaa: 0.0 ± 0.0
Ser	6.449SerAla: 6.449 ± 0.071	0.267SerCys: 0.267 ± 0.014	2.823SerAsp: 2.823 ± 0.045	2.044SerGlu: 2.044 ± 0.04	1.572SerPhe: 1.572 ± 0.035	5.422SerGly: 5.422 ± 0.069	0.895SerHis: 0.895 ± 0.023	1.476SerIle: 1.476 ± 0.033	0.703SerLys: 0.703 ± 0.023	4.499SerLeu: 4.499 ± 0.061	1.001SerMet: 1.001 ± 0.032	0.776SerAsn: 0.776 ± 0.027	3.047SerPro: 3.047 ± 0.048	1.089SerGln: 1.089 ± 0.027	3.55SerArg: 3.55 ± 0.046	2.924SerSer: 2.924 ± 0.05	3.538SerThr: 3.538 ± 0.05	4.338SerVal: 4.338 ± 0.068	0.966SerTrp: 0.966 ± 0.026	0.991SerTyr: 0.991 ± 0.028	0.0SerXaa: 0.0 ± 0.0
Thr	8.564ThrAla: 8.564 ± 0.071	0.313ThrCys: 0.313 ± 0.014	3.924ThrAsp: 3.924 ± 0.062	2.918ThrGlu: 2.918 ± 0.051	1.992ThrPhe: 1.992 ± 0.042	6.438ThrGly: 6.438 ± 0.089	1.168ThrHis: 1.168 ± 0.027	1.954ThrIle: 1.954 ± 0.041	0.924ThrLys: 0.924 ± 0.029	6.022ThrLeu: 6.022 ± 0.07	0.962ThrMet: 0.962 ± 0.027	0.971ThrAsn: 0.971 ± 0.032	4.296ThrPro: 4.296 ± 0.053	1.41ThrGln: 1.41 ± 0.034	3.923ThrArg: 3.923 ± 0.054	3.518ThrSer: 3.518 ± 0.054	4.98ThrThr: 4.98 ± 0.073	6.52ThrVal: 6.52 ± 0.075	1.1ThrTrp: 1.1 ± 0.031	1.325ThrTyr: 1.325 ± 0.032	0.0ThrXaa: 0.0 ± 0.0
Val	14.984ValAla: 14.984 ± 0.147	0.54ValCys: 0.54 ± 0.02	6.834ValAsp: 6.834 ± 0.073	5.543ValGlu: 5.543 ± 0.064	2.393ValPhe: 2.393 ± 0.048	8.647ValGly: 8.647 ± 0.09	1.989ValHis: 1.989 ± 0.042	2.516ValIle: 2.516 ± 0.05	1.255ValLys: 1.255 ± 0.03	11.243ValLeu: 11.243 ± 0.133	1.42ValMet: 1.42 ± 0.041	1.425ValAsn: 1.425 ± 0.031	6.208ValPro: 6.208 ± 0.073	2.188ValGln: 2.188 ± 0.038	7.871ValArg: 7.871 ± 0.088	4.463ValSer: 4.463 ± 0.059	6.605ValThr: 6.605 ± 0.082	12.6ValVal: 12.6 ± 0.141	1.269ValTrp: 1.269 ± 0.029	1.563ValTyr: 1.563 ± 0.031	0.0ValXaa: 0.0 ± 0.0
Trp	1.848TrpAla: 1.848 ± 0.036	0.116TrpCys: 0.116 ± 0.009	1.014TrpAsp: 1.014 ± 0.033	0.683TrpGlu: 0.683 ± 0.02	0.622TrpPhe: 0.622 ± 0.023	1.232TrpGly: 1.232 ± 0.032	0.357TrpHis: 0.357 ± 0.016	0.488TrpIle: 0.488 ± 0.019	0.236TrpLys: 0.236 ± 0.013	1.769TrpLeu: 1.769 ± 0.045	0.278TrpMet: 0.278 ± 0.013	0.368TrpAsn: 0.368 ± 0.017	0.811TrpPro: 0.811 ± 0.024	0.552TrpGln: 0.552 ± 0.019	1.428TrpArg: 1.428 ± 0.033	1.058TrpSer: 1.058 ± 0.029	1.065TrpThr: 1.065 ± 0.028	1.352TrpVal: 1.352 ± 0.031	0.424TrpTrp: 0.424 ± 0.017	0.339TrpTyr: 0.339 ± 0.014	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.5TyrAla: 2.5 ± 0.038	0.099TyrCys: 0.099 ± 0.008	1.4TyrAsp: 1.4 ± 0.044	1.02TyrGlu: 1.02 ± 0.027	0.556TyrPhe: 0.556 ± 0.018	1.88TyrGly: 1.88 ± 0.038	0.328TyrHis: 0.328 ± 0.017	0.341TyrIle: 0.341 ± 0.016	0.249TyrLys: 0.249 ± 0.015	2.148TyrLeu: 2.148 ± 0.04	0.208TyrMet: 0.208 ± 0.013	0.336TyrAsn: 0.336 ± 0.016	1.041TyrPro: 1.041 ± 0.029	0.515TyrGln: 0.515 ± 0.02	1.588TyrArg: 1.588 ± 0.03	0.909TyrSer: 0.909 ± 0.027	1.1TyrThr: 1.1 ± 0.033	1.773TyrVal: 1.773 ± 0.033	0.341TyrTrp: 0.341 ± 0.016	0.436TyrTyr: 0.436 ± 0.018	0.001TyrXaa: 0.001 ± 0.001
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.001XaaAsp: 0.001 ± 0.001	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.002XaaXaa: 0.002 ± 0.002

Statistics based on 4296 proteins (1480017 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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