Amino acid dipepetide frequency for Phycicoccus duodecadis

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	22.465AlaAla: 22.465 ± 0.24	0.962AlaCys: 0.962 ± 0.034	8.634AlaAsp: 8.634 ± 0.105	7.595AlaGlu: 7.595 ± 0.108	3.512AlaPhe: 3.512 ± 0.054	13.669AlaGly: 13.669 ± 0.129	2.806AlaHis: 2.806 ± 0.05	3.483AlaIle: 3.483 ± 0.065	2.305AlaLys: 2.305 ± 0.068	14.859AlaLeu: 14.859 ± 0.163	2.717AlaMet: 2.717 ± 0.049	1.823AlaAsn: 1.823 ± 0.047	7.168AlaPro: 7.168 ± 0.103	3.564AlaGln: 3.564 ± 0.052	10.905AlaArg: 10.905 ± 0.131	6.425AlaSer: 6.425 ± 0.094	8.137AlaThr: 8.137 ± 0.105	13.793AlaVal: 13.793 ± 0.142	2.093AlaTrp: 2.093 ± 0.047	2.35AlaTyr: 2.35 ± 0.05	0.0AlaXaa: 0.0 ± 0.0
Cys	0.893CysAla: 0.893 ± 0.028	0.077CysCys: 0.077 ± 0.009	0.451CysAsp: 0.451 ± 0.021	0.347CysGlu: 0.347 ± 0.018	0.215CysPhe: 0.215 ± 0.014	0.807CysGly: 0.807 ± 0.029	0.174CysHis: 0.174 ± 0.012	0.171CysIle: 0.171 ± 0.015	0.078CysLys: 0.078 ± 0.008	0.553CysLeu: 0.553 ± 0.022	0.09CysMet: 0.09 ± 0.009	0.113CysAsn: 0.113 ± 0.012	0.459CysPro: 0.459 ± 0.021	0.131CysGln: 0.131 ± 0.01	0.588CysArg: 0.588 ± 0.029	0.373CysSer: 0.373 ± 0.019	0.489CysThr: 0.489 ± 0.024	0.57CysVal: 0.57 ± 0.024	0.094CysTrp: 0.094 ± 0.01	0.115CysTyr: 0.115 ± 0.011	0.0CysXaa: 0.0 ± 0.0
Asp	8.762AspAla: 8.762 ± 0.1	0.327AspCys: 0.327 ± 0.017	4.637AspAsp: 4.637 ± 0.083	4.276AspGlu: 4.276 ± 0.083	1.381AspPhe: 1.381 ± 0.041	6.443AspGly: 6.443 ± 0.09	1.474AspHis: 1.474 ± 0.039	1.829AspIle: 1.829 ± 0.042	0.826AspLys: 0.826 ± 0.033	7.101AspLeu: 7.101 ± 0.088	0.695AspMet: 0.695 ± 0.025	0.786AspAsn: 0.786 ± 0.034	4.739AspPro: 4.739 ± 0.065	1.457AspGln: 1.457 ± 0.033	4.783AspArg: 4.783 ± 0.079	2.004AspSer: 2.004 ± 0.042	3.166AspThr: 3.166 ± 0.06	6.249AspVal: 6.249 ± 0.083	0.854AspTrp: 0.854 ± 0.034	1.016AspTyr: 1.016 ± 0.037	0.0AspXaa: 0.0 ± 0.0
Glu	7.562GluAla: 7.562 ± 0.111	0.344GluCys: 0.344 ± 0.017	2.698GluAsp: 2.698 ± 0.059	2.836GluGlu: 2.836 ± 0.059	1.24GluPhe: 1.24 ± 0.037	4.415GluGly: 4.415 ± 0.067	1.742GluHis: 1.742 ± 0.049	1.896GluIle: 1.896 ± 0.045	1.144GluLys: 1.144 ± 0.044	5.668GluLeu: 5.668 ± 0.08	0.825GluMet: 0.825 ± 0.03	0.869GluAsn: 0.869 ± 0.03	3.18GluPro: 3.18 ± 0.068	1.932GluGln: 1.932 ± 0.046	5.531GluArg: 5.531 ± 0.088	2.265GluSer: 2.265 ± 0.05	2.66GluThr: 2.66 ± 0.054	5.647GluVal: 5.647 ± 0.081	0.763GluTrp: 0.763 ± 0.031	0.989GluTyr: 0.989 ± 0.032	0.0GluXaa: 0.0 ± 0.0
Phe	3.428PheAla: 3.428 ± 0.069	0.216PheCys: 0.216 ± 0.015	1.842PheAsp: 1.842 ± 0.043	1.362PheGlu: 1.362 ± 0.039	0.815PhePhe: 0.815 ± 0.033	2.902PheGly: 2.902 ± 0.063	0.552PheHis: 0.552 ± 0.024	0.665PheIle: 0.665 ± 0.029	0.407PheLys: 0.407 ± 0.021	2.429PheLeu: 2.429 ± 0.053	0.368PheMet: 0.368 ± 0.019	0.446PheAsn: 0.446 ± 0.022	1.331PhePro: 1.331 ± 0.034	0.573PheGln: 0.573 ± 0.025	1.659PheArg: 1.659 ± 0.04	1.361PheSer: 1.361 ± 0.04	1.764PheThr: 1.764 ± 0.045	2.699PheVal: 2.699 ± 0.052	0.388PheTrp: 0.388 ± 0.019	0.537PheTyr: 0.537 ± 0.022	0.0PheXaa: 0.0 ± 0.0
Gly	11.74GlyAla: 11.74 ± 0.127	0.753GlyCys: 0.753 ± 0.032	5.351GlyAsp: 5.351 ± 0.076	4.938GlyGlu: 4.938 ± 0.072	2.838GlyPhe: 2.838 ± 0.061	8.802GlyGly: 8.802 ± 0.126	2.222GlyHis: 2.222 ± 0.045	3.486GlyIle: 3.486 ± 0.061	1.816GlyLys: 1.816 ± 0.05	9.861GlyLeu: 9.861 ± 0.097	2.305GlyMet: 2.305 ± 0.044	1.468GlyAsn: 1.468 ± 0.045	5.185GlyPro: 5.185 ± 0.078	2.433GlyGln: 2.433 ± 0.053	8.077GlyArg: 8.077 ± 0.09	5.662GlySer: 5.662 ± 0.081	6.056GlyThr: 6.056 ± 0.078	9.276GlyVal: 9.276 ± 0.107	1.861GlyTrp: 1.861 ± 0.046	2.118GlyTyr: 2.118 ± 0.049	0.0GlyXaa: 0.0 ± 0.0
His	2.599HisAla: 2.599 ± 0.056	0.195HisCys: 0.195 ± 0.014	1.669HisAsp: 1.669 ± 0.041	1.328HisGlu: 1.328 ± 0.041	0.518HisPhe: 0.518 ± 0.024	2.291HisGly: 2.291 ± 0.046	0.725HisHis: 0.725 ± 0.03	0.491HisIle: 0.491 ± 0.023	0.257HisLys: 0.257 ± 0.016	2.445HisLeu: 2.445 ± 0.052	0.244HisMet: 0.244 ± 0.015	0.334HisAsn: 0.334 ± 0.019	1.781HisPro: 1.781 ± 0.039	0.566HisGln: 0.566 ± 0.024	1.985HisArg: 1.985 ± 0.041	0.85HisSer: 0.85 ± 0.029	1.119HisThr: 1.119 ± 0.034	2.156HisVal: 2.156 ± 0.047	0.342HisTrp: 0.342 ± 0.018	0.408HisTyr: 0.408 ± 0.022	0.0HisXaa: 0.0 ± 0.0
Ile	4.156IleAla: 4.156 ± 0.073	0.245IleCys: 0.245 ± 0.014	2.109IleAsp: 2.109 ± 0.049	1.757IleGlu: 1.757 ± 0.045	0.689IlePhe: 0.689 ± 0.03	3.215IleGly: 3.215 ± 0.061	0.576IleHis: 0.576 ± 0.025	0.914IleIle: 0.914 ± 0.034	0.586IleLys: 0.586 ± 0.028	2.322IleLeu: 2.322 ± 0.057	0.382IleMet: 0.382 ± 0.02	0.568IleAsn: 0.568 ± 0.024	1.662IlePro: 1.662 ± 0.038	0.7IleGln: 0.7 ± 0.027	2.001IleArg: 2.001 ± 0.046	1.441IleSer: 1.441 ± 0.042	1.89IleThr: 1.89 ± 0.049	2.747IleVal: 2.747 ± 0.055	0.32IleTrp: 0.32 ± 0.018	0.504IleTyr: 0.504 ± 0.022	0.0IleXaa: 0.0 ± 0.0
Lys	2.447LysAla: 2.447 ± 0.069	0.083LysCys: 0.083 ± 0.009	1.07LysAsp: 1.07 ± 0.034	0.886LysGlu: 0.886 ± 0.032	0.351LysPhe: 0.351 ± 0.022	1.544LysGly: 1.544 ± 0.047	0.337LysHis: 0.337 ± 0.019	0.64LysIle: 0.64 ± 0.03	0.66LysLys: 0.66 ± 0.036	1.333LysLeu: 1.333 ± 0.039	0.305LysMet: 0.305 ± 0.019	0.426LysAsn: 0.426 ± 0.023	0.925LysPro: 0.925 ± 0.033	0.5LysGln: 0.5 ± 0.022	1.151LysArg: 1.151 ± 0.039	0.839LysSer: 0.839 ± 0.034	1.016LysThr: 1.016 ± 0.033	1.727LysVal: 1.727 ± 0.052	0.173LysTrp: 0.173 ± 0.013	0.393LysTyr: 0.393 ± 0.019	0.0LysXaa: 0.0 ± 0.0
Leu	15.879LeuAla: 15.879 ± 0.151	0.6LeuCys: 0.6 ± 0.023	7.101LeuAsp: 7.101 ± 0.096	5.32LeuGlu: 5.32 ± 0.082	2.199LeuPhe: 2.199 ± 0.052	10.409LeuGly: 10.409 ± 0.114	2.131LeuHis: 2.131 ± 0.05	2.168LeuIle: 2.168 ± 0.056	1.47LeuLys: 1.47 ± 0.045	10.602LeuLeu: 10.602 ± 0.149	1.5LeuMet: 1.5 ± 0.034	1.348LeuAsn: 1.348 ± 0.044	5.831LeuPro: 5.831 ± 0.075	2.101LeuGln: 2.101 ± 0.045	8.225LeuArg: 8.225 ± 0.118	4.928LeuSer: 4.928 ± 0.072	6.353LeuThr: 6.353 ± 0.085	11.564LeuVal: 11.564 ± 0.139	1.211LeuTrp: 1.211 ± 0.032	1.491LeuTyr: 1.491 ± 0.037	0.0LeuXaa: 0.0 ± 0.0
Met	2.454MetAla: 2.454 ± 0.041	0.114MetCys: 0.114 ± 0.011	0.872MetAsp: 0.872 ± 0.034	0.692MetGlu: 0.692 ± 0.025	0.462MetPhe: 0.462 ± 0.024	1.425MetGly: 1.425 ± 0.036	0.314MetHis: 0.314 ± 0.018	0.529MetIle: 0.529 ± 0.022	0.389MetLys: 0.389 ± 0.018	1.656MetLeu: 1.656 ± 0.039	0.279MetMet: 0.279 ± 0.016	0.361MetAsn: 0.361 ± 0.018	1.134MetPro: 1.134 ± 0.029	0.413MetGln: 0.413 ± 0.02	1.446MetArg: 1.446 ± 0.04	1.514MetSer: 1.514 ± 0.033	1.678MetThr: 1.678 ± 0.037	1.474MetVal: 1.474 ± 0.039	0.206MetTrp: 0.206 ± 0.015	0.29MetTyr: 0.29 ± 0.017	0.0MetXaa: 0.0 ± 0.0
Asn	1.937AsnAla: 1.937 ± 0.047	0.12AsnCys: 0.12 ± 0.01	0.906AsnAsp: 0.906 ± 0.035	0.671AsnGlu: 0.671 ± 0.027	0.388AsnPhe: 0.388 ± 0.018	1.529AsnGly: 1.529 ± 0.057	0.358AsnHis: 0.358 ± 0.02	0.592AsnIle: 0.592 ± 0.026	0.296AsnLys: 0.296 ± 0.018	1.564AsnLeu: 1.564 ± 0.044	0.224AsnMet: 0.224 ± 0.017	0.379AsnAsn: 0.379 ± 0.024	1.247AsnPro: 1.247 ± 0.035	0.414AsnGln: 0.414 ± 0.021	1.065AsnArg: 1.065 ± 0.036	0.665AsnSer: 0.665 ± 0.027	0.914AsnThr: 0.914 ± 0.03	1.416AsnVal: 1.416 ± 0.041	0.202AsnTrp: 0.202 ± 0.014	0.328AsnTyr: 0.328 ± 0.017	0.0AsnXaa: 0.0 ± 0.0
Pro	8.162ProAla: 8.162 ± 0.101	0.303ProCys: 0.303 ± 0.018	4.438ProAsp: 4.438 ± 0.06	3.896ProGlu: 3.896 ± 0.074	1.534ProPhe: 1.534 ± 0.04	6.432ProGly: 6.432 ± 0.086	1.291ProHis: 1.291 ± 0.029	1.27ProIle: 1.27 ± 0.037	0.904ProLys: 0.904 ± 0.031	5.052ProLeu: 5.052 ± 0.076	1.043ProMet: 1.043 ± 0.033	0.803ProAsn: 0.803 ± 0.027	3.246ProPro: 3.246 ± 0.078	1.483ProGln: 1.483 ± 0.036	4.127ProArg: 4.127 ± 0.069	3.305ProSer: 3.305 ± 0.06	3.8ProThr: 3.8 ± 0.068	5.968ProVal: 5.968 ± 0.089	1.03ProTrp: 1.03 ± 0.033	1.031ProTyr: 1.031 ± 0.03	0.0ProXaa: 0.0 ± 0.0
Gln	3.281GlnAla: 3.281 ± 0.062	0.149GlnCys: 0.149 ± 0.013	1.301GlnAsp: 1.301 ± 0.034	1.223GlnGlu: 1.223 ± 0.035	0.637GlnPhe: 0.637 ± 0.028	2.164GlnGly: 2.164 ± 0.052	0.63GlnHis: 0.63 ± 0.026	0.834GlnIle: 0.834 ± 0.028	0.516GlnLys: 0.516 ± 0.026	2.473GlnLeu: 2.473 ± 0.046	0.492GlnMet: 0.492 ± 0.024	0.448GlnAsn: 0.448 ± 0.024	1.358GlnPro: 1.358 ± 0.04	1.038GlnGln: 1.038 ± 0.033	2.313GlnArg: 2.313 ± 0.058	1.078GlnSer: 1.078 ± 0.033	1.241GlnThr: 1.241 ± 0.036	2.738GlnVal: 2.738 ± 0.058	0.44GlnTrp: 0.44 ± 0.02	0.535GlnTyr: 0.535 ± 0.023	0.0GlnXaa: 0.0 ± 0.0
Arg	10.436ArgAla: 10.436 ± 0.131	0.51ArgCys: 0.51 ± 0.024	4.679ArgAsp: 4.679 ± 0.07	4.52ArgGlu: 4.52 ± 0.09	2.239ArgPhe: 2.239 ± 0.05	6.444ArgGly: 6.444 ± 0.09	1.955ArgHis: 1.955 ± 0.046	2.792ArgIle: 2.792 ± 0.059	1.107ArgLys: 1.107 ± 0.036	8.625ArgLeu: 8.625 ± 0.113	1.917ArgMet: 1.917 ± 0.043	1.019ArgAsn: 1.019 ± 0.033	4.997ArgPro: 4.997 ± 0.087	1.952ArgGln: 1.952 ± 0.042	8.108ArgArg: 8.108 ± 0.125	4.167ArgSer: 4.167 ± 0.069	4.812ArgThr: 4.812 ± 0.069	7.258ArgVal: 7.258 ± 0.094	1.495ArgTrp: 1.495 ± 0.039	1.579ArgTyr: 1.579 ± 0.038	0.0ArgXaa: 0.0 ± 0.0
Ser	6.434SerAla: 6.434 ± 0.103	0.328SerCys: 0.328 ± 0.02	2.707SerAsp: 2.707 ± 0.054	2.257SerGlu: 2.257 ± 0.053	1.484SerPhe: 1.484 ± 0.039	5.526SerGly: 5.526 ± 0.086	0.945SerHis: 0.945 ± 0.032	1.597SerIle: 1.597 ± 0.042	0.843SerLys: 0.843 ± 0.031	4.886SerLeu: 4.886 ± 0.076	1.164SerMet: 1.164 ± 0.031	0.799SerAsn: 0.799 ± 0.03	3.119SerPro: 3.119 ± 0.057	1.152SerGln: 1.152 ± 0.034	3.796SerArg: 3.796 ± 0.063	2.923SerSer: 2.923 ± 0.063	3.427SerThr: 3.427 ± 0.067	4.656SerVal: 4.656 ± 0.061	0.852SerTrp: 0.852 ± 0.027	1.059SerTyr: 1.059 ± 0.032	0.0SerXaa: 0.0 ± 0.0
Thr	8.106ThrAla: 8.106 ± 0.107	0.456ThrCys: 0.456 ± 0.019	3.665ThrAsp: 3.665 ± 0.058	2.837ThrGlu: 2.837 ± 0.052	1.741ThrPhe: 1.741 ± 0.046	6.312ThrGly: 6.312 ± 0.089	1.229ThrHis: 1.229 ± 0.035	1.844ThrIle: 1.844 ± 0.046	1.118ThrLys: 1.118 ± 0.035	5.885ThrLeu: 5.885 ± 0.084	1.097ThrMet: 1.097 ± 0.032	0.991ThrAsn: 0.991 ± 0.036	4.31ThrPro: 4.31 ± 0.064	1.341ThrGln: 1.341 ± 0.039	4.19ThrArg: 4.19 ± 0.068	3.351ThrSer: 3.351 ± 0.059	4.376ThrThr: 4.376 ± 0.076	6.391ThrVal: 6.391 ± 0.106	1.009ThrTrp: 1.009 ± 0.035	1.316ThrTyr: 1.316 ± 0.039	0.0ThrXaa: 0.0 ± 0.0
Val	14.301ValAla: 14.301 ± 0.155	0.717ValCys: 0.717 ± 0.025	6.523ValAsp: 6.523 ± 0.076	5.827ValGlu: 5.827 ± 0.085	2.41ValPhe: 2.41 ± 0.051	8.948ValGly: 8.948 ± 0.1	2.152ValHis: 2.152 ± 0.042	2.837ValIle: 2.837 ± 0.053	1.529ValLys: 1.529 ± 0.044	11.299ValLeu: 11.299 ± 0.146	1.576ValMet: 1.576 ± 0.036	1.568ValAsn: 1.568 ± 0.044	5.698ValPro: 5.698 ± 0.076	2.175ValGln: 2.175 ± 0.045	7.744ValArg: 7.744 ± 0.102	4.928ValSer: 4.928 ± 0.065	6.717ValThr: 6.717 ± 0.088	12.524ValVal: 12.524 ± 0.147	1.249ValTrp: 1.249 ± 0.034	1.45ValTyr: 1.45 ± 0.036	0.0ValXaa: 0.0 ± 0.0
Trp	1.834TrpAla: 1.834 ± 0.048	0.161TrpCys: 0.161 ± 0.011	0.816TrpAsp: 0.816 ± 0.031	0.639TrpGlu: 0.639 ± 0.021	0.555TrpPhe: 0.555 ± 0.022	1.172TrpGly: 1.172 ± 0.036	0.327TrpHis: 0.327 ± 0.017	0.34TrpIle: 0.34 ± 0.018	0.249TrpLys: 0.249 ± 0.017	1.803TrpLeu: 1.803 ± 0.051	0.298TrpMet: 0.298 ± 0.018	0.345TrpAsn: 0.345 ± 0.019	0.805TrpPro: 0.805 ± 0.028	0.47TrpGln: 0.47 ± 0.022	1.347TrpArg: 1.347 ± 0.037	0.994TrpSer: 0.994 ± 0.028	0.88TrpThr: 0.88 ± 0.029	1.519TrpVal: 1.519 ± 0.041	0.387TrpTrp: 0.387 ± 0.02	0.283TrpTyr: 0.283 ± 0.018	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.388TyrAla: 2.388 ± 0.053	0.126TyrCys: 0.126 ± 0.01	1.334TyrAsp: 1.334 ± 0.041	1.0TyrGlu: 1.0 ± 0.031	0.539TyrPhe: 0.539 ± 0.024	1.8TyrGly: 1.8 ± 0.045	0.366TyrHis: 0.366 ± 0.02	0.407TyrIle: 0.407 ± 0.021	0.306TyrLys: 0.306 ± 0.017	2.013TyrLeu: 2.013 ± 0.039	0.178TyrMet: 0.178 ± 0.015	0.32TyrAsn: 0.32 ± 0.019	0.945TyrPro: 0.945 ± 0.034	0.494TyrGln: 0.494 ± 0.024	1.572TyrArg: 1.572 ± 0.046	0.88TyrSer: 0.88 ± 0.029	1.07TyrThr: 1.07 ± 0.033	1.799TyrVal: 1.799 ± 0.036	0.258TyrTrp: 0.258 ± 0.017	0.373TyrTyr: 0.373 ± 0.018	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 3172 proteins (1065718 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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