Amino acid dipepetide frequency for Cordyceps javanica

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	13.058AlaAla: 13.058 ± 0.099	1.253AlaCys: 1.253 ± 0.015	5.185AlaAsp: 5.185 ± 0.034	5.418AlaGlu: 5.418 ± 0.043	3.265AlaPhe: 3.265 ± 0.029	6.877AlaGly: 6.877 ± 0.044	2.024AlaHis: 2.024 ± 0.021	4.185AlaIle: 4.185 ± 0.034	4.237AlaLys: 4.237 ± 0.041	8.437AlaLeu: 8.437 ± 0.05	2.203AlaMet: 2.203 ± 0.024	3.074AlaAsn: 3.074 ± 0.026	5.36AlaPro: 5.36 ± 0.046	3.672AlaGln: 3.672 ± 0.034	5.866AlaArg: 5.866 ± 0.038	7.902AlaSer: 7.902 ± 0.044	6.071AlaThr: 6.071 ± 0.043	6.366AlaVal: 6.366 ± 0.037	1.31AlaTrp: 1.31 ± 0.017	2.228AlaTyr: 2.228 ± 0.022	0.0AlaXaa: 0.0 ± 0.0
Cys	1.122CysAla: 1.122 ± 0.015	0.288CysCys: 0.288 ± 0.008	0.715CysAsp: 0.715 ± 0.012	0.602CysGlu: 0.602 ± 0.01	0.576CysPhe: 0.576 ± 0.013	1.014CysGly: 1.014 ± 0.018	0.371CysHis: 0.371 ± 0.01	0.715CysIle: 0.715 ± 0.012	0.519CysLys: 0.519 ± 0.01	1.327CysLeu: 1.327 ± 0.019	0.287CysMet: 0.287 ± 0.008	0.446CysAsn: 0.446 ± 0.01	0.718CysPro: 0.718 ± 0.015	0.481CysGln: 0.481 ± 0.01	0.895CysArg: 0.895 ± 0.013	0.953CysSer: 0.953 ± 0.016	0.746CysThr: 0.746 ± 0.014	0.869CysVal: 0.869 ± 0.014	0.21CysTrp: 0.21 ± 0.007	0.355CysTyr: 0.355 ± 0.008	0.0CysXaa: 0.0 ± 0.0
Asp	5.787AspAla: 5.787 ± 0.042	0.711AspCys: 0.711 ± 0.013	4.93AspAsp: 4.93 ± 0.049	4.546AspGlu: 4.546 ± 0.038	2.163AspPhe: 2.163 ± 0.024	4.712AspGly: 4.712 ± 0.032	1.222AspHis: 1.222 ± 0.018	2.787AspIle: 2.787 ± 0.028	2.531AspLys: 2.531 ± 0.027	4.796AspLeu: 4.796 ± 0.033	1.402AspMet: 1.402 ± 0.017	1.863AspAsn: 1.863 ± 0.02	2.989AspPro: 2.989 ± 0.024	1.781AspGln: 1.781 ± 0.019	3.151AspArg: 3.151 ± 0.031	4.034AspSer: 4.034 ± 0.036	2.911AspThr: 2.911 ± 0.023	3.794AspVal: 3.794 ± 0.032	0.887AspTrp: 0.887 ± 0.015	1.54AspTyr: 1.54 ± 0.019	0.0AspXaa: 0.0 ± 0.0
Glu	5.728GluAla: 5.728 ± 0.042	0.623GluCys: 0.623 ± 0.013	3.903GluAsp: 3.903 ± 0.034	4.781GluGlu: 4.781 ± 0.046	1.827GluPhe: 1.827 ± 0.018	3.287GluGly: 3.287 ± 0.029	1.358GluHis: 1.358 ± 0.016	2.609GluIle: 2.609 ± 0.023	3.14GluLys: 3.14 ± 0.03	5.033GluLeu: 5.033 ± 0.037	1.434GluMet: 1.434 ± 0.016	2.021GluAsn: 2.021 ± 0.02	2.799GluPro: 2.799 ± 0.036	2.453GluGln: 2.453 ± 0.024	3.785GluArg: 3.785 ± 0.032	3.975GluSer: 3.975 ± 0.031	3.386GluThr: 3.386 ± 0.031	3.183GluVal: 3.183 ± 0.028	0.814GluTrp: 0.814 ± 0.013	1.542GluTyr: 1.542 ± 0.019	0.0GluXaa: 0.0 ± 0.0
Phe	3.327PheAla: 3.327 ± 0.028	0.577PheCys: 0.577 ± 0.011	2.265PheAsp: 2.265 ± 0.023	1.97PheGlu: 1.97 ± 0.019	1.631PhePhe: 1.631 ± 0.023	2.809PheGly: 2.809 ± 0.027	0.868PheHis: 0.868 ± 0.014	1.654PheIle: 1.654 ± 0.02	1.364PheLys: 1.364 ± 0.018	3.376PheLeu: 3.376 ± 0.029	0.785PheMet: 0.785 ± 0.013	1.326PheAsn: 1.326 ± 0.016	1.802PhePro: 1.802 ± 0.018	1.328PheGln: 1.328 ± 0.016	1.979PheArg: 1.979 ± 0.02	2.837PheSer: 2.837 ± 0.024	2.017PheThr: 2.017 ± 0.02	2.413PheVal: 2.413 ± 0.025	0.649PheTrp: 0.649 ± 0.011	1.066PheTyr: 1.066 ± 0.015	0.0PheXaa: 0.0 ± 0.0
Gly	6.287GlyAla: 6.287 ± 0.05	0.958GlyCys: 0.958 ± 0.015	3.986GlyAsp: 3.986 ± 0.037	3.526GlyGlu: 3.526 ± 0.029	2.691GlyPhe: 2.691 ± 0.024	6.976GlyGly: 6.976 ± 0.07	1.784GlyHis: 1.784 ± 0.024	3.344GlyIle: 3.344 ± 0.032	3.37GlyLys: 3.37 ± 0.031	6.007GlyLeu: 6.007 ± 0.042	1.581GlyMet: 1.581 ± 0.022	2.561GlyAsn: 2.561 ± 0.029	3.433GlyPro: 3.433 ± 0.04	2.712GlyGln: 2.712 ± 0.026	4.641GlyArg: 4.641 ± 0.035	5.959GlySer: 5.959 ± 0.044	4.03GlyThr: 4.03 ± 0.03	4.404GlyVal: 4.404 ± 0.032	1.183GlyTrp: 1.183 ± 0.015	2.077GlyTyr: 2.077 ± 0.025	0.0GlyXaa: 0.0 ± 0.0
His	2.102HisAla: 2.102 ± 0.021	0.371HisCys: 0.371 ± 0.009	1.455HisAsp: 1.455 ± 0.017	1.283HisGlu: 1.283 ± 0.015	0.898HisPhe: 0.898 ± 0.014	1.911HisGly: 1.911 ± 0.025	0.966HisHis: 0.966 ± 0.018	1.143HisIle: 1.143 ± 0.015	0.878HisLys: 0.878 ± 0.013	2.173HisLeu: 2.173 ± 0.024	0.542HisMet: 0.542 ± 0.011	0.83HisAsn: 0.83 ± 0.012	1.543HisPro: 1.543 ± 0.018	1.027HisGln: 1.027 ± 0.016	1.64HisArg: 1.64 ± 0.021	1.762HisSer: 1.762 ± 0.019	1.217HisThr: 1.217 ± 0.018	1.527HisVal: 1.527 ± 0.018	0.351HisTrp: 0.351 ± 0.009	0.678HisTyr: 0.678 ± 0.012	0.0HisXaa: 0.0 ± 0.0
Ile	4.169IleAla: 4.169 ± 0.032	0.72IleCys: 0.72 ± 0.014	2.728IleAsp: 2.728 ± 0.027	2.517IleGlu: 2.517 ± 0.023	1.836IlePhe: 1.836 ± 0.024	3.051IleGly: 3.051 ± 0.03	1.102IleHis: 1.102 ± 0.012	2.251IleIle: 2.251 ± 0.027	1.996IleLys: 1.996 ± 0.023	4.196IleLeu: 4.196 ± 0.032	1.02IleMet: 1.02 ± 0.016	1.602IleAsn: 1.602 ± 0.019	2.61IlePro: 2.61 ± 0.022	1.69IleGln: 1.69 ± 0.02	2.687IleArg: 2.687 ± 0.025	3.414IleSer: 3.414 ± 0.026	2.562IleThr: 2.562 ± 0.027	3.061IleVal: 3.061 ± 0.028	0.652IleTrp: 0.652 ± 0.012	1.263IleTyr: 1.263 ± 0.016	0.0IleXaa: 0.0 ± 0.0
Lys	4.133LysAla: 4.133 ± 0.034	0.482LysCys: 0.482 ± 0.01	2.606LysAsp: 2.606 ± 0.027	2.877LysGlu: 2.877 ± 0.037	1.407LysPhe: 1.407 ± 0.019	2.683LysGly: 2.683 ± 0.028	1.059LysHis: 1.059 ± 0.016	2.027LysIle: 2.027 ± 0.02	3.04LysLys: 3.04 ± 0.049	3.944LysLeu: 3.944 ± 0.03	1.021LysMet: 1.021 ± 0.014	1.617LysAsn: 1.617 ± 0.019	2.583LysPro: 2.583 ± 0.028	1.855LysGln: 1.855 ± 0.024	3.201LysArg: 3.201 ± 0.032	3.273LysSer: 3.273 ± 0.032	2.8LysThr: 2.8 ± 0.023	2.587LysVal: 2.587 ± 0.026	0.617LysTrp: 0.617 ± 0.01	1.235LysTyr: 1.235 ± 0.015	0.0LysXaa: 0.0 ± 0.0
Leu	8.762LeuAla: 8.762 ± 0.052	1.303LeuCys: 1.303 ± 0.019	5.234LeuAsp: 5.234 ± 0.038	5.104LeuGlu: 5.104 ± 0.04	3.296LeuPhe: 3.296 ± 0.031	6.044LeuGly: 6.044 ± 0.04	2.287LeuHis: 2.287 ± 0.026	3.617LeuIle: 3.617 ± 0.036	3.66LeuLys: 3.66 ± 0.032	8.507LeuLeu: 8.507 ± 0.065	1.766LeuMet: 1.766 ± 0.02	2.809LeuAsn: 2.809 ± 0.025	5.516LeuPro: 5.516 ± 0.039	3.796LeuGln: 3.796 ± 0.032	6.066LeuArg: 6.066 ± 0.04	7.024LeuSer: 7.024 ± 0.043	4.616LeuThr: 4.616 ± 0.034	5.665LeuVal: 5.665 ± 0.046	1.226LeuTrp: 1.226 ± 0.016	2.283LeuTyr: 2.283 ± 0.022	0.0LeuXaa: 0.0 ± 0.0
Met	2.445MetAla: 2.445 ± 0.023	0.272MetCys: 0.272 ± 0.006	1.263MetAsp: 1.263 ± 0.014	1.248MetGlu: 1.248 ± 0.017	0.711MetPhe: 0.711 ± 0.011	1.479MetGly: 1.479 ± 0.018	0.526MetHis: 0.526 ± 0.009	0.924MetIle: 0.924 ± 0.014	0.973MetLys: 0.973 ± 0.013	1.961MetLeu: 1.961 ± 0.021	0.627MetMet: 0.627 ± 0.013	0.762MetAsn: 0.762 ± 0.014	1.398MetPro: 1.398 ± 0.02	0.906MetGln: 0.906 ± 0.016	1.394MetArg: 1.394 ± 0.016	1.85MetSer: 1.85 ± 0.018	1.386MetThr: 1.386 ± 0.016	1.327MetVal: 1.327 ± 0.016	0.262MetTrp: 0.262 ± 0.007	0.547MetTyr: 0.547 ± 0.01	0.0MetXaa: 0.0 ± 0.0
Asn	3.116AsnAla: 3.116 ± 0.026	0.455AsnCys: 0.455 ± 0.01	1.886AsnAsp: 1.886 ± 0.017	1.782AsnGlu: 1.782 ± 0.018	1.241AsnPhe: 1.241 ± 0.013	2.92AsnGly: 2.92 ± 0.03	0.803AsnHis: 0.803 ± 0.012	1.82AsnIle: 1.82 ± 0.019	1.514AsnLys: 1.514 ± 0.018	3.0AsnLeu: 3.0 ± 0.029	0.887AsnMet: 0.887 ± 0.013	1.437AsnAsn: 1.437 ± 0.025	2.097AsnPro: 2.097 ± 0.022	1.195AsnGln: 1.195 ± 0.019	1.853AsnArg: 1.853 ± 0.02	2.525AsnSer: 2.525 ± 0.024	1.989AsnThr: 1.989 ± 0.021	2.234AsnVal: 2.234 ± 0.021	0.511AsnTrp: 0.511 ± 0.01	0.967AsnTyr: 0.967 ± 0.014	0.0AsnXaa: 0.0 ± 0.0
Pro	6.007ProAla: 6.007 ± 0.054	0.62ProCys: 0.62 ± 0.012	3.235ProAsp: 3.235 ± 0.025	3.558ProGlu: 3.558 ± 0.03	1.951ProPhe: 1.951 ± 0.022	4.096ProGly: 4.096 ± 0.043	1.268ProHis: 1.268 ± 0.016	2.239ProIle: 2.239 ± 0.021	2.409ProLys: 2.409 ± 0.025	4.657ProLeu: 4.657 ± 0.034	1.089ProMet: 1.089 ± 0.017	1.949ProAsn: 1.949 ± 0.019	5.259ProPro: 5.259 ± 0.082	2.357ProGln: 2.357 ± 0.029	3.594ProArg: 3.594 ± 0.032	5.569ProSer: 5.569 ± 0.044	3.687ProThr: 3.687 ± 0.032	3.686ProVal: 3.686 ± 0.036	0.744ProTrp: 0.744 ± 0.012	1.381ProTyr: 1.381 ± 0.019	0.001ProXaa: 0.001 ± 0.0
Gln	3.63GlnAla: 3.63 ± 0.032	0.466GlnCys: 0.466 ± 0.011	2.143GlnAsp: 2.143 ± 0.019	2.198GlnGlu: 2.198 ± 0.023	1.259GlnPhe: 1.259 ± 0.014	2.445GlnGly: 2.445 ± 0.023	1.186GlnHis: 1.186 ± 0.016	1.707GlnIle: 1.707 ± 0.016	1.826GlnLys: 1.826 ± 0.019	3.586GlnLeu: 3.586 ± 0.031	0.897GlnMet: 0.897 ± 0.014	1.408GlnAsn: 1.408 ± 0.019	2.569GlnPro: 2.569 ± 0.032	2.896GlnGln: 2.896 ± 0.064	2.78GlnArg: 2.78 ± 0.025	2.975GlnSer: 2.975 ± 0.03	2.242GlnThr: 2.242 ± 0.021	2.228GlnVal: 2.228 ± 0.021	0.556GlnTrp: 0.556 ± 0.01	1.103GlnTyr: 1.103 ± 0.016	0.0GlnXaa: 0.0 ± 0.0
Arg	5.512ArgAla: 5.512 ± 0.034	0.847ArgCys: 0.847 ± 0.013	3.703ArgAsp: 3.703 ± 0.035	3.653ArgGlu: 3.653 ± 0.033	2.17ArgPhe: 2.17 ± 0.021	4.167ArgGly: 4.167 ± 0.037	1.814ArgHis: 1.814 ± 0.022	2.841ArgIle: 2.841 ± 0.024	3.187ArgLys: 3.187 ± 0.027	5.82ArgLeu: 5.82 ± 0.038	1.374ArgMet: 1.374 ± 0.018	2.18ArgAsn: 2.18 ± 0.022	3.756ArgPro: 3.756 ± 0.033	2.834ArgGln: 2.834 ± 0.027	5.833ArgArg: 5.833 ± 0.048	4.833ArgSer: 4.833 ± 0.042	3.283ArgThr: 3.283 ± 0.028	3.601ArgVal: 3.601 ± 0.029	0.993ArgTrp: 0.993 ± 0.014	1.672ArgTyr: 1.672 ± 0.019	0.0ArgXaa: 0.0 ± 0.0
Ser	7.201SerAla: 7.201 ± 0.049	0.972SerCys: 0.972 ± 0.017	4.142SerAsp: 4.142 ± 0.032	3.768SerGlu: 3.768 ± 0.031	2.891SerPhe: 2.891 ± 0.023	5.7SerGly: 5.7 ± 0.045	1.911SerHis: 1.911 ± 0.022	3.673SerIle: 3.673 ± 0.028	3.464SerLys: 3.464 ± 0.03	6.983SerLeu: 6.983 ± 0.044	1.731SerMet: 1.731 ± 0.02	2.729SerAsn: 2.729 ± 0.021	5.136SerPro: 5.136 ± 0.051	3.11SerGln: 3.11 ± 0.029	5.143SerArg: 5.143 ± 0.045	8.689SerSer: 8.689 ± 0.075	5.188SerThr: 5.188 ± 0.05	4.642SerVal: 4.642 ± 0.027	1.108SerTrp: 1.108 ± 0.014	1.934SerTyr: 1.934 ± 0.022	0.0SerXaa: 0.0 ± 0.0
Thr	5.843ThrAla: 5.843 ± 0.035	0.753ThrCys: 0.753 ± 0.014	2.813ThrAsp: 2.813 ± 0.028	2.984ThrGlu: 2.984 ± 0.031	2.113ThrPhe: 2.113 ± 0.02	4.247ThrGly: 4.247 ± 0.043	1.244ThrHis: 1.244 ± 0.018	2.817ThrIle: 2.817 ± 0.027	2.501ThrLys: 2.501 ± 0.021	5.127ThrLeu: 5.127 ± 0.036	1.25ThrMet: 1.25 ± 0.015	1.92ThrAsn: 1.92 ± 0.018	4.055ThrPro: 4.055 ± 0.038	1.981ThrGln: 1.981 ± 0.018	3.245ThrArg: 3.245 ± 0.027	5.014ThrSer: 5.014 ± 0.043	4.411ThrThr: 4.411 ± 0.049	3.848ThrVal: 3.848 ± 0.029	0.804ThrTrp: 0.804 ± 0.012	1.497ThrTyr: 1.497 ± 0.017	0.0ThrXaa: 0.0 ± 0.0
Val	6.288ValAla: 6.288 ± 0.043	0.912ValCys: 0.912 ± 0.015	3.858ValAsp: 3.858 ± 0.029	3.646ValGlu: 3.646 ± 0.032	2.461ValPhe: 2.461 ± 0.024	4.168ValGly: 4.168 ± 0.035	1.401ValHis: 1.401 ± 0.014	2.795ValIle: 2.795 ± 0.028	2.644ValLys: 2.644 ± 0.023	5.778ValLeu: 5.778 ± 0.043	1.364ValMet: 1.364 ± 0.018	2.082ValAsn: 2.082 ± 0.021	3.698ValPro: 3.698 ± 0.03	2.375ValGln: 2.375 ± 0.02	3.703ValArg: 3.703 ± 0.034	4.592ValSer: 4.592 ± 0.033	3.544ValThr: 3.544 ± 0.03	4.609ValVal: 4.609 ± 0.037	0.887ValTrp: 0.887 ± 0.016	1.689ValTyr: 1.689 ± 0.017	0.0ValXaa: 0.0 ± 0.0
Trp	1.229TrpAla: 1.229 ± 0.016	0.203TrpCys: 0.203 ± 0.006	0.884TrpAsp: 0.884 ± 0.013	0.794TrpGlu: 0.794 ± 0.013	0.528TrpPhe: 0.528 ± 0.011	0.911TrpGly: 0.911 ± 0.014	0.376TrpHis: 0.376 ± 0.008	0.706TrpIle: 0.706 ± 0.014	0.71TrpLys: 0.71 ± 0.013	1.392TrpLeu: 1.392 ± 0.019	0.364TrpMet: 0.364 ± 0.008	0.585TrpAsn: 0.585 ± 0.013	0.665TrpPro: 0.665 ± 0.011	0.61TrpGln: 0.61 ± 0.011	1.026TrpArg: 1.026 ± 0.016	1.043TrpSer: 1.043 ± 0.014	0.891TrpThr: 0.891 ± 0.013	0.865TrpVal: 0.865 ± 0.014	0.287TrpTrp: 0.287 ± 0.009	0.425TrpTyr: 0.425 ± 0.009	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.245TyrAla: 2.245 ± 0.019	0.423TyrCys: 0.423 ± 0.011	1.604TyrAsp: 1.604 ± 0.022	1.428TyrGlu: 1.428 ± 0.016	1.127TyrPhe: 1.127 ± 0.018	2.014TyrGly: 2.014 ± 0.023	0.729TyrHis: 0.729 ± 0.011	1.274TyrIle: 1.274 ± 0.016	1.083TyrLys: 1.083 ± 0.014	2.481TyrLeu: 2.481 ± 0.026	0.636TyrMet: 0.636 ± 0.01	1.03TyrAsn: 1.03 ± 0.014	1.37TyrPro: 1.37 ± 0.017	1.04TyrGln: 1.04 ± 0.016	1.59TyrArg: 1.59 ± 0.018	1.891TyrSer: 1.891 ± 0.021	1.49TyrThr: 1.49 ± 0.02	1.585TyrVal: 1.585 ± 0.017	0.444TyrTrp: 0.444 ± 0.01	0.886TyrTyr: 0.886 ± 0.014	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.001XaaGly: 0.001 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.001XaaPro: 0.001 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.013XaaXaa: 0.013 ± 0.006

Statistics based on 11436 proteins (5262576 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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