Amino acid dipepetide frequency for Ardenticatena maritima

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	12.689AlaAla: 12.689 ± 0.16	0.963AlaCys: 0.963 ± 0.036	5.624AlaAsp: 5.624 ± 0.082	7.278AlaGlu: 7.278 ± 0.115	4.599AlaPhe: 4.599 ± 0.072	6.922AlaGly: 6.922 ± 0.1	3.173AlaHis: 3.173 ± 0.062	5.656AlaIle: 5.656 ± 0.08	2.188AlaLys: 2.188 ± 0.058	14.398AlaLeu: 14.398 ± 0.159	2.759AlaMet: 2.759 ± 0.053	2.659AlaAsn: 2.659 ± 0.058	5.617AlaPro: 5.617 ± 0.092	4.431AlaGln: 4.431 ± 0.074	8.503AlaArg: 8.503 ± 0.115	4.115AlaSer: 4.115 ± 0.076	6.123AlaThr: 6.123 ± 0.09	7.854AlaVal: 7.854 ± 0.097	2.21AlaTrp: 2.21 ± 0.057	3.149AlaTyr: 3.149 ± 0.058	0.018AlaXaa: 0.018 ± 0.004
Cys	0.729CysAla: 0.729 ± 0.028	0.077CysCys: 0.077 ± 0.008	0.398CysAsp: 0.398 ± 0.019	0.414CysGlu: 0.414 ± 0.017	0.249CysPhe: 0.249 ± 0.015	0.749CysGly: 0.749 ± 0.03	0.218CysHis: 0.218 ± 0.019	0.318CysIle: 0.318 ± 0.019	0.131CysLys: 0.131 ± 0.012	0.567CysLeu: 0.567 ± 0.028	0.121CysMet: 0.121 ± 0.011	0.206CysAsn: 0.206 ± 0.015	0.496CysPro: 0.496 ± 0.024	0.191CysGln: 0.191 ± 0.015	0.529CysArg: 0.529 ± 0.022	0.327CysSer: 0.327 ± 0.019	0.424CysThr: 0.424 ± 0.02	0.478CysVal: 0.478 ± 0.023	0.112CysTrp: 0.112 ± 0.013	0.2CysTyr: 0.2 ± 0.012	0.002CysXaa: 0.002 ± 0.001
Asp	6.031AspAla: 6.031 ± 0.092	0.255AspCys: 0.255 ± 0.018	3.043AspAsp: 3.043 ± 0.077	4.682AspGlu: 4.682 ± 0.076	1.88AspPhe: 1.88 ± 0.051	4.046AspGly: 4.046 ± 0.081	1.06AspHis: 1.06 ± 0.036	3.254AspIle: 3.254 ± 0.053	1.035AspLys: 1.035 ± 0.035	5.232AspLeu: 5.232 ± 0.071	1.093AspMet: 1.093 ± 0.032	1.093AspAsn: 1.093 ± 0.036	3.12AspPro: 3.12 ± 0.063	1.22AspGln: 1.22 ± 0.035	2.915AspArg: 2.915 ± 0.055	1.318AspSer: 1.318 ± 0.038	2.86AspThr: 2.86 ± 0.055	4.98AspVal: 4.98 ± 0.069	0.918AspTrp: 0.918 ± 0.033	1.343AspTyr: 1.343 ± 0.039	0.0AspXaa: 0.0 ± 0.0
Glu	8.247GluAla: 8.247 ± 0.138	0.343GluCys: 0.343 ± 0.02	2.874GluAsp: 2.874 ± 0.062	5.31GluGlu: 5.31 ± 0.109	1.751GluPhe: 1.751 ± 0.042	4.681GluGly: 4.681 ± 0.08	1.93GluHis: 1.93 ± 0.044	3.391GluIle: 3.391 ± 0.064	1.972GluLys: 1.972 ± 0.056	5.216GluLeu: 5.216 ± 0.088	1.748GluMet: 1.748 ± 0.045	1.771GluAsn: 1.771 ± 0.045	3.223GluPro: 3.223 ± 0.06	3.309GluGln: 3.309 ± 0.064	6.008GluArg: 6.008 ± 0.102	2.389GluSer: 2.389 ± 0.052	4.744GluThr: 4.744 ± 0.085	4.517GluVal: 4.517 ± 0.076	1.278GluTrp: 1.278 ± 0.041	1.587GluTyr: 1.587 ± 0.041	0.011GluXaa: 0.011 ± 0.003
Phe	3.887PheAla: 3.887 ± 0.072	0.335PheCys: 0.335 ± 0.019	2.509PheAsp: 2.509 ± 0.049	2.336PheGlu: 2.336 ± 0.052	1.784PhePhe: 1.784 ± 0.045	3.208PheGly: 3.208 ± 0.062	0.76PheHis: 0.76 ± 0.029	1.986PheIle: 1.986 ± 0.048	0.827PheLys: 0.827 ± 0.031	3.905PheLeu: 3.905 ± 0.084	0.772PheMet: 0.772 ± 0.028	1.045PheAsn: 1.045 ± 0.039	1.75PhePro: 1.75 ± 0.036	1.054PheGln: 1.054 ± 0.036	2.061PheArg: 2.061 ± 0.047	1.829PheSer: 1.829 ± 0.047	2.194PheThr: 2.194 ± 0.049	3.246PheVal: 3.246 ± 0.058	0.828PheTrp: 0.828 ± 0.033	1.31PheTyr: 1.31 ± 0.036	0.001PheXaa: 0.001 ± 0.001
Gly	7.331GlyAla: 7.331 ± 0.098	0.611GlyCys: 0.611 ± 0.027	3.879GlyAsp: 3.879 ± 0.073	4.827GlyGlu: 4.827 ± 0.072	2.868GlyPhe: 2.868 ± 0.063	5.877GlyGly: 5.877 ± 0.099	1.71GlyHis: 1.71 ± 0.038	3.956GlyIle: 3.956 ± 0.065	2.239GlyLys: 2.239 ± 0.053	7.525GlyLeu: 7.525 ± 0.096	1.929GlyMet: 1.929 ± 0.048	1.924GlyAsn: 1.924 ± 0.049	2.462GlyPro: 2.462 ± 0.053	2.378GlyGln: 2.378 ± 0.053	5.344GlyArg: 5.344 ± 0.066	2.867GlySer: 2.867 ± 0.059	4.288GlyThr: 4.288 ± 0.08	6.851GlyVal: 6.851 ± 0.09	1.522GlyTrp: 1.522 ± 0.046	2.438GlyTyr: 2.438 ± 0.047	0.017GlyXaa: 0.017 ± 0.004
His	2.852HisAla: 2.852 ± 0.054	0.202HisCys: 0.202 ± 0.014	1.237HisAsp: 1.237 ± 0.037	1.539HisGlu: 1.539 ± 0.04	0.918HisPhe: 0.918 ± 0.032	1.885HisGly: 1.885 ± 0.05	0.785HisHis: 0.785 ± 0.031	1.579HisIle: 1.579 ± 0.045	0.539HisLys: 0.539 ± 0.022	2.924HisLeu: 2.924 ± 0.067	0.545HisMet: 0.545 ± 0.022	0.677HisAsn: 0.677 ± 0.026	1.827HisPro: 1.827 ± 0.044	0.766HisGln: 0.766 ± 0.028	1.643HisArg: 1.643 ± 0.045	0.918HisSer: 0.918 ± 0.028	1.65HisThr: 1.65 ± 0.046	2.102HisVal: 2.102 ± 0.044	0.413HisTrp: 0.413 ± 0.02	0.634HisTyr: 0.634 ± 0.024	0.001HisXaa: 0.001 ± 0.001
Ile	6.205IleAla: 6.205 ± 0.083	0.384IleCys: 0.384 ± 0.019	2.542IleAsp: 2.542 ± 0.049	4.021IleGlu: 4.021 ± 0.072	1.952IlePhe: 1.952 ± 0.05	4.049IleGly: 4.049 ± 0.072	1.138IleHis: 1.138 ± 0.036	2.579IleIle: 2.579 ± 0.065	1.128IleLys: 1.128 ± 0.035	5.02IleLeu: 5.02 ± 0.082	0.862IleMet: 0.862 ± 0.029	1.291IleAsn: 1.291 ± 0.038	2.952IlePro: 2.952 ± 0.054	1.595IleGln: 1.595 ± 0.045	3.448IleArg: 3.448 ± 0.052	2.145IleSer: 2.145 ± 0.053	3.181IleThr: 3.181 ± 0.059	4.572IleVal: 4.572 ± 0.071	0.744IleTrp: 0.744 ± 0.026	1.317IleTyr: 1.317 ± 0.038	0.005IleXaa: 0.005 ± 0.002
Lys	2.507LysAla: 2.507 ± 0.06	0.153LysCys: 0.153 ± 0.014	0.933LysAsp: 0.933 ± 0.03	1.571LysGlu: 1.571 ± 0.05	0.614LysPhe: 0.614 ± 0.025	1.835LysGly: 1.835 ± 0.049	0.576LysHis: 0.576 ± 0.027	1.177LysIle: 1.177 ± 0.043	0.906LysLys: 0.906 ± 0.039	1.946LysLeu: 1.946 ± 0.057	0.628LysMet: 0.628 ± 0.027	0.657LysAsn: 0.657 ± 0.025	1.623LysPro: 1.623 ± 0.039	1.007LysGln: 1.007 ± 0.032	2.322LysArg: 2.322 ± 0.056	1.017LysSer: 1.017 ± 0.037	1.462LysThr: 1.462 ± 0.04	1.744LysVal: 1.744 ± 0.053	0.359LysTrp: 0.359 ± 0.018	0.64LysTyr: 0.64 ± 0.03	0.0LysXaa: 0.0 ± 0.0
Leu	13.52LeuAla: 13.52 ± 0.173	0.677LeuCys: 0.677 ± 0.023	6.192LeuAsp: 6.192 ± 0.082	6.299LeuGlu: 6.299 ± 0.098	4.371LeuPhe: 4.371 ± 0.076	7.971LeuGly: 7.971 ± 0.103	2.76LeuHis: 2.76 ± 0.064	4.988LeuIle: 4.988 ± 0.075	2.46LeuLys: 2.46 ± 0.055	12.809LeuLeu: 12.809 ± 0.168	2.23LeuMet: 2.23 ± 0.049	2.812LeuAsn: 2.812 ± 0.058	6.311LeuPro: 6.311 ± 0.083	3.784LeuGln: 3.784 ± 0.07	7.997LeuArg: 7.997 ± 0.106	5.098LeuSer: 5.098 ± 0.082	6.165LeuThr: 6.165 ± 0.082	8.624LeuVal: 8.624 ± 0.108	1.797LeuTrp: 1.797 ± 0.055	2.919LeuTyr: 2.919 ± 0.054	0.016LeuXaa: 0.016 ± 0.004
Met	2.511MetAla: 2.511 ± 0.048	0.141MetCys: 0.141 ± 0.014	0.864MetAsp: 0.864 ± 0.03	1.056MetGlu: 1.056 ± 0.03	0.68MetPhe: 0.68 ± 0.026	1.581MetGly: 1.581 ± 0.043	0.54MetHis: 0.54 ± 0.02	0.897MetIle: 0.897 ± 0.028	0.644MetLys: 0.644 ± 0.023	2.599MetLeu: 2.599 ± 0.057	0.461MetMet: 0.461 ± 0.022	0.692MetAsn: 0.692 ± 0.022	1.437MetPro: 1.437 ± 0.037	1.039MetGln: 1.039 ± 0.03	1.958MetArg: 1.958 ± 0.045	1.265MetSer: 1.265 ± 0.038	1.437MetThr: 1.437 ± 0.039	1.634MetVal: 1.634 ± 0.044	0.307MetTrp: 0.307 ± 0.017	0.501MetTyr: 0.501 ± 0.024	0.002MetXaa: 0.002 ± 0.002
Asn	3.178AsnAla: 3.178 ± 0.061	0.199AsnCys: 0.199 ± 0.014	1.367AsnAsp: 1.367 ± 0.037	1.619AsnGlu: 1.619 ± 0.04	0.853AsnPhe: 0.853 ± 0.036	2.115AsnGly: 2.115 ± 0.055	0.512AsnHis: 0.512 ± 0.022	1.519AsnIle: 1.519 ± 0.039	0.596AsnLys: 0.596 ± 0.026	2.573AsnLeu: 2.573 ± 0.055	0.548AsnMet: 0.548 ± 0.023	0.802AsnAsn: 0.802 ± 0.031	1.942AsnPro: 1.942 ± 0.048	0.825AsnGln: 0.825 ± 0.028	1.82AsnArg: 1.82 ± 0.035	1.016AsnSer: 1.016 ± 0.04	1.603AsnThr: 1.603 ± 0.049	2.243AsnVal: 2.243 ± 0.051	0.397AsnTrp: 0.397 ± 0.023	0.604AsnTyr: 0.604 ± 0.027	0.005AsnXaa: 0.005 ± 0.002
Pro	5.397ProAla: 5.397 ± 0.078	0.31ProCys: 0.31 ± 0.017	4.041ProAsp: 4.041 ± 0.062	4.263ProGlu: 4.263 ± 0.079	2.313ProPhe: 2.313 ± 0.05	3.683ProGly: 3.683 ± 0.07	1.721ProHis: 1.721 ± 0.045	2.63ProIle: 2.63 ± 0.044	1.24ProLys: 1.24 ± 0.035	6.257ProLeu: 6.257 ± 0.09	1.168ProMet: 1.168 ± 0.032	1.856ProAsn: 1.856 ± 0.044	4.195ProPro: 4.195 ± 0.082	1.953ProGln: 1.953 ± 0.044	3.504ProArg: 3.504 ± 0.054	2.61ProSer: 2.61 ± 0.054	4.237ProThr: 4.237 ± 0.1	4.267ProVal: 4.267 ± 0.069	0.944ProTrp: 0.944 ± 0.034	1.481ProTyr: 1.481 ± 0.038	0.007ProXaa: 0.007 ± 0.003
Gln	4.711GlnAla: 4.711 ± 0.092	0.207GlnCys: 0.207 ± 0.017	1.282GlnAsp: 1.282 ± 0.039	2.22GlnGlu: 2.22 ± 0.055	1.124GlnPhe: 1.124 ± 0.033	2.454GlnGly: 2.454 ± 0.053	1.058GlnHis: 1.058 ± 0.037	1.64GlnIle: 1.64 ± 0.043	1.113GlnLys: 1.113 ± 0.035	3.001GlnLeu: 3.001 ± 0.058	0.918GlnMet: 0.918 ± 0.031	0.983GlnAsn: 0.983 ± 0.031	2.262GlnPro: 2.262 ± 0.05	1.873GlnGln: 1.873 ± 0.053	3.483GlnArg: 3.483 ± 0.063	1.635GlnSer: 1.635 ± 0.041	2.488GlnThr: 2.488 ± 0.057	2.668GlnVal: 2.668 ± 0.059	0.609GlnTrp: 0.609 ± 0.03	0.851GlnTyr: 0.851 ± 0.029	0.001GlnXaa: 0.001 ± 0.001
Arg	7.751ArgAla: 7.751 ± 0.098	0.413ArgCys: 0.413 ± 0.024	3.679ArgAsp: 3.679 ± 0.064	5.47ArgGlu: 5.47 ± 0.091	3.01ArgPhe: 3.01 ± 0.051	4.53ArgGly: 4.53 ± 0.074	2.021ArgHis: 2.021 ± 0.049	4.216ArgIle: 4.216 ± 0.07	1.88ArgLys: 1.88 ± 0.048	9.379ArgLeu: 9.379 ± 0.121	1.764ArgMet: 1.764 ± 0.045	1.771ArgAsn: 1.771 ± 0.051	3.651ArgPro: 3.651 ± 0.056	2.961ArgGln: 2.961 ± 0.055	6.615ArgArg: 6.615 ± 0.1	2.513ArgSer: 2.513 ± 0.054	4.041ArgThr: 4.041 ± 0.064	5.574ArgVal: 5.574 ± 0.074	1.459ArgTrp: 1.459 ± 0.045	2.41ArgTyr: 2.41 ± 0.048	0.01ArgXaa: 0.01 ± 0.003
Ser	4.337SerAla: 4.337 ± 0.077	0.26SerCys: 0.26 ± 0.018	2.044SerAsp: 2.044 ± 0.045	2.425SerGlu: 2.425 ± 0.047	1.514SerPhe: 1.514 ± 0.037	3.574SerGly: 3.574 ± 0.072	0.963SerHis: 0.963 ± 0.029	2.114SerIle: 2.114 ± 0.054	0.961SerLys: 0.961 ± 0.034	4.384SerLeu: 4.384 ± 0.074	1.06SerMet: 1.06 ± 0.032	1.104SerAsn: 1.104 ± 0.038	3.063SerPro: 3.063 ± 0.061	1.384SerGln: 1.384 ± 0.038	2.747SerArg: 2.747 ± 0.045	1.947SerSer: 1.947 ± 0.051	2.463SerThr: 2.463 ± 0.055	2.947SerVal: 2.947 ± 0.058	0.569SerTrp: 0.569 ± 0.026	0.942SerTyr: 0.942 ± 0.029	0.002SerXaa: 0.002 ± 0.001
Thr	5.65ThrAla: 5.65 ± 0.091	0.424ThrCys: 0.424 ± 0.022	2.609ThrAsp: 2.609 ± 0.058	2.677ThrGlu: 2.677 ± 0.06	2.679ThrPhe: 2.679 ± 0.055	4.104ThrGly: 4.104 ± 0.072	1.534ThrHis: 1.534 ± 0.039	3.479ThrIle: 3.479 ± 0.063	1.04ThrLys: 1.04 ± 0.037	7.375ThrLeu: 7.375 ± 0.108	1.184ThrMet: 1.184 ± 0.031	1.586ThrAsn: 1.586 ± 0.046	5.45ThrPro: 5.45 ± 0.106	1.738ThrGln: 1.738 ± 0.045	3.536ThrArg: 3.536 ± 0.059	2.543ThrSer: 2.543 ± 0.057	3.646ThrThr: 3.646 ± 0.08	4.548ThrVal: 4.548 ± 0.08	1.111ThrTrp: 1.111 ± 0.033	1.865ThrTyr: 1.865 ± 0.046	0.005ThrXaa: 0.005 ± 0.002
Val	8.792ValAla: 8.792 ± 0.107	0.631ValCys: 0.631 ± 0.025	3.796ValAsp: 3.796 ± 0.072	5.413ValGlu: 5.413 ± 0.082	2.757ValPhe: 2.757 ± 0.054	5.958ValGly: 5.958 ± 0.089	1.883ValHis: 1.883 ± 0.046	3.865ValIle: 3.865 ± 0.065	1.718ValLys: 1.718 ± 0.057	9.269ValLeu: 9.269 ± 0.113	1.592ValMet: 1.592 ± 0.047	2.035ValAsn: 2.035 ± 0.044	4.498ValPro: 4.498 ± 0.069	3.156ValGln: 3.156 ± 0.057	6.536ValArg: 6.536 ± 0.085	3.523ValSer: 3.523 ± 0.058	3.273ValThr: 3.273 ± 0.063	7.276ValVal: 7.276 ± 0.101	1.547ValTrp: 1.547 ± 0.049	2.093ValTyr: 2.093 ± 0.051	0.006ValXaa: 0.006 ± 0.002
Trp	1.594TrpAla: 1.594 ± 0.046	0.144TrpCys: 0.144 ± 0.011	0.746TrpAsp: 0.746 ± 0.028	1.015TrpGlu: 1.015 ± 0.031	0.659TrpPhe: 0.659 ± 0.029	1.37TrpGly: 1.37 ± 0.036	0.563TrpHis: 0.563 ± 0.023	0.607TrpIle: 0.607 ± 0.022	0.426TrpLys: 0.426 ± 0.024	2.564TrpLeu: 2.564 ± 0.067	0.381TrpMet: 0.381 ± 0.021	0.512TrpAsn: 0.512 ± 0.024	0.786TrpPro: 0.786 ± 0.03	1.001TrpGln: 1.001 ± 0.03	1.925TrpArg: 1.925 ± 0.055	0.706TrpSer: 0.706 ± 0.031	0.733TrpThr: 0.733 ± 0.028	1.317TrpVal: 1.317 ± 0.038	0.471TrpTrp: 0.471 ± 0.026	0.534TrpTyr: 0.534 ± 0.025	0.002TrpXaa: 0.002 ± 0.001
Tyr	3.0TyrAla: 3.0 ± 0.059	0.202TyrCys: 0.202 ± 0.016	1.714TyrAsp: 1.714 ± 0.045	1.862TyrGlu: 1.862 ± 0.04	1.048TyrPhe: 1.048 ± 0.03	2.241TyrGly: 2.241 ± 0.039	0.727TyrHis: 0.727 ± 0.027	1.276TyrIle: 1.276 ± 0.033	0.632TyrLys: 0.632 ± 0.025	2.847TyrLeu: 2.847 ± 0.057	0.48TyrMet: 0.48 ± 0.022	0.857TyrAsn: 0.857 ± 0.031	1.401TyrPro: 1.401 ± 0.041	0.916TyrGln: 0.916 ± 0.031	2.208TyrArg: 2.208 ± 0.043	1.016TyrSer: 1.016 ± 0.036	1.761TyrThr: 1.761 ± 0.049	2.169TyrVal: 2.169 ± 0.051	0.46TyrTrp: 0.46 ± 0.021	0.823TyrTyr: 0.823 ± 0.03	0.003TyrXaa: 0.003 ± 0.002
Xaa	0.009XaaAla: 0.009 ± 0.003	0.004XaaCys: 0.004 ± 0.002	0.005XaaAsp: 0.005 ± 0.002	0.001XaaGlu: 0.001 ± 0.001	0.004XaaPhe: 0.004 ± 0.002	0.009XaaGly: 0.009 ± 0.003	0.006XaaHis: 0.006 ± 0.002	0.004XaaIle: 0.004 ± 0.002	0.004XaaLys: 0.004 ± 0.002	0.009XaaLeu: 0.009 ± 0.003	0.001XaaMet: 0.001 ± 0.001	0.002XaaAsn: 0.002 ± 0.001	0.013XaaPro: 0.013 ± 0.004	0.001XaaGln: 0.001 ± 0.001	0.017XaaArg: 0.017 ± 0.004	0.007XaaSer: 0.007 ± 0.003	0.01XaaThr: 0.01 ± 0.003	0.005XaaVal: 0.005 ± 0.002	0.002XaaTrp: 0.002 ± 0.001	0.001XaaTyr: 0.001 ± 0.001	0.376XaaXaa: 0.376 ± 0.038

Statistics based on 3144 proteins (1012731 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

---