Amino acid dipepetide frequency for Wenzhou picorna-like virus 51

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
6.102AlaAla: 6.102 ± 0.701
1.592AlaCys: 1.592 ± 0.328
3.98AlaAsp: 3.98 ± 0.104
2.388AlaGlu: 2.388 ± 0.703
4.51AlaPhe: 4.51 ± 0.372
6.102AlaGly: 6.102 ± 0.734
1.592AlaHis: 1.592 ± 0.328
3.98AlaIle: 3.98 ± 0.104
3.184AlaLys: 3.184 ± 0.3
5.837AlaLeu: 5.837 ± 1.523
1.592AlaMet: 1.592 ± 0.328
2.388AlaAsn: 2.388 ± 1.181
5.837AlaPro: 5.837 ± 2.303
2.919AlaGln: 2.919 ± 0.912
3.715AlaArg: 3.715 ± 0.031
8.49AlaSer: 8.49 ± 0.48
2.123AlaThr: 2.123 ± 0.119
3.98AlaVal: 3.98 ± 0.375
1.327AlaTrp: 1.327 ± 0.194
2.653AlaTyr: 2.653 ± 0.569
0.0AlaXaa: 0.0 ± 0.0
Cys
1.061CysAla: 1.061 ± 0.538
0.796CysCys: 0.796 ± 0.403
0.796CysAsp: 0.796 ± 0.403
1.061CysGlu: 1.061 ± 0.538
1.327CysPhe: 1.327 ± 0.672
1.857CysGly: 1.857 ± 0.941
0.265CysHis: 0.265 ± 0.134
0.531CysIle: 0.531 ± 0.209
1.592CysLys: 1.592 ± 0.807
1.857CysLeu: 1.857 ± 0.941
0.265CysMet: 0.265 ± 0.134
0.531CysAsn: 0.531 ± 0.269
0.531CysPro: 0.531 ± 0.269
0.265CysGln: 0.265 ± 0.134
3.449CysArg: 3.449 ± 0.644
0.796CysSer: 0.796 ± 0.075
0.265CysThr: 0.265 ± 0.134
0.531CysVal: 0.531 ± 0.269
0.265CysTrp: 0.265 ± 0.344
1.061CysTyr: 1.061 ± 0.538
0.0CysXaa: 0.0 ± 0.0
Asp
2.388AspAla: 2.388 ± 0.225
2.123AspCys: 2.123 ± 0.597
3.715AspAsp: 3.715 ± 0.509
3.184AspGlu: 3.184 ± 0.3
4.776AspPhe: 4.776 ± 0.029
5.306AspGly: 5.306 ± 0.776
1.592AspHis: 1.592 ± 0.807
2.919AspIle: 2.919 ± 0.912
3.715AspLys: 3.715 ± 1.882
5.837AspLeu: 5.837 ± 0.566
1.857AspMet: 1.857 ± 0.015
2.653AspAsn: 2.653 ± 0.388
3.98AspPro: 3.98 ± 0.853
1.061AspGln: 1.061 ± 0.538
2.653AspArg: 2.653 ± 0.388
4.776AspSer: 4.776 ± 0.45
2.123AspThr: 2.123 ± 0.597
3.98AspVal: 3.98 ± 0.582
1.327AspTrp: 1.327 ± 0.284
2.123AspTyr: 2.123 ± 0.597
0.0AspXaa: 0.0 ± 0.0
Glu
3.715GluAla: 3.715 ± 0.987
1.327GluCys: 1.327 ± 0.194
4.245GluAsp: 4.245 ± 0.238
3.98GluGlu: 3.98 ± 1.06
2.388GluPhe: 2.388 ± 0.732
2.123GluGly: 2.123 ± 0.359
0.265GluHis: 0.265 ± 0.134
1.857GluIle: 1.857 ± 0.494
3.449GluLys: 3.449 ± 0.165
3.449GluLeu: 3.449 ± 1.269
2.123GluMet: 2.123 ± 0.837
2.123GluAsn: 2.123 ± 0.119
3.184GluPro: 3.184 ± 0.778
1.061GluGln: 1.061 ± 0.538
3.449GluArg: 3.449 ± 1.269
4.776GluSer: 4.776 ± 0.507
2.653GluThr: 2.653 ± 0.09
3.184GluVal: 3.184 ± 1.256
1.061GluTrp: 1.061 ± 0.538
0.796GluTyr: 0.796 ± 0.075
0.0GluXaa: 0.0 ± 0.0
Phe
2.653PheAla: 2.653 ± 0.388
1.061PheCys: 1.061 ± 0.538
3.449PheAsp: 3.449 ± 1.269
4.776PheGlu: 4.776 ± 0.507
1.327PhePhe: 1.327 ± 0.284
2.919PheGly: 2.919 ± 0.912
0.796PheHis: 0.796 ± 0.403
2.919PheIle: 2.919 ± 0.044
2.919PheLys: 2.919 ± 1.001
4.245PheLeu: 4.245 ± 0.238
0.265PheMet: 0.265 ± 0.104
1.592PheAsn: 1.592 ± 0.628
3.449PhePro: 3.449 ± 1.122
1.327PheGln: 1.327 ± 0.763
2.653PheArg: 2.653 ± 0.866
5.306PheSer: 5.306 ± 0.776
3.449PheThr: 3.449 ± 0.791
5.306PheVal: 5.306 ± 1.254
0.796PheTrp: 0.796 ± 0.553
2.919PheTyr: 2.919 ± 0.522
0.0PheXaa: 0.0 ± 0.0
Gly
5.041GlyAla: 5.041 ± 0.315
0.796GlyCys: 0.796 ± 0.075
6.102GlyAsp: 6.102 ± 2.169
4.776GlyGlu: 4.776 ± 0.507
2.653GlyPhe: 2.653 ± 0.388
3.98GlyGly: 3.98 ± 0.375
1.857GlyHis: 1.857 ± 0.941
2.919GlyIle: 2.919 ± 0.522
3.184GlyLys: 3.184 ± 0.3
4.51GlyLeu: 4.51 ± 0.372
1.857GlyMet: 1.857 ± 0.494
2.388GlyAsn: 2.388 ± 1.66
3.715GlyPro: 3.715 ± 0.509
2.919GlyGln: 2.919 ± 0.912
3.184GlyArg: 3.184 ± 0.3
6.898GlySer: 6.898 ± 0.148
3.449GlyThr: 3.449 ± 1.6
6.368GlyVal: 6.368 ± 0.357
0.265GlyTrp: 0.265 ± 0.134
2.123GlyTyr: 2.123 ± 0.359
0.0GlyXaa: 0.0 ± 0.0
His
2.388HisAla: 2.388 ± 0.253
0.265HisCys: 0.265 ± 0.134
2.388HisAsp: 2.388 ± 1.21
1.061HisGlu: 1.061 ± 0.538
1.061HisPhe: 1.061 ± 0.06
1.857HisGly: 1.857 ± 0.941
0.796HisHis: 0.796 ± 0.403
0.0HisIle: 0.0 ± 0.0
1.327HisLys: 1.327 ± 0.672
1.592HisLeu: 1.592 ± 0.328
1.857HisMet: 1.857 ± 0.972
0.796HisAsn: 0.796 ± 0.403
1.061HisPro: 1.061 ± 0.06
0.265HisGln: 0.265 ± 0.134
0.265HisArg: 0.265 ± 0.344
2.919HisSer: 2.919 ± 1.001
1.061HisThr: 1.061 ± 0.538
2.388HisVal: 2.388 ± 0.225
0.265HisTrp: 0.265 ± 0.134
1.857HisTyr: 1.857 ± 0.463
0.0HisXaa: 0.0 ± 0.0
Ile
2.653IleAla: 2.653 ± 0.569
1.061IleCys: 1.061 ± 0.06
2.919IleAsp: 2.919 ± 0.434
1.592IleGlu: 1.592 ± 0.328
2.653IlePhe: 2.653 ± 0.866
2.919IleGly: 2.919 ± 1.001
1.061IleHis: 1.061 ± 0.06
1.327IleIle: 1.327 ± 0.672
2.653IleLys: 2.653 ± 1.344
2.653IleLeu: 2.653 ± 0.388
2.653IleMet: 2.653 ± 0.388
3.98IleAsn: 3.98 ± 0.104
3.184IlePro: 3.184 ± 1.256
0.796IleGln: 0.796 ± 0.553
2.388IleArg: 2.388 ± 0.732
3.449IleSer: 3.449 ± 0.644
3.184IleThr: 3.184 ± 0.657
2.123IleVal: 2.123 ± 0.837
0.265IleTrp: 0.265 ± 0.344
1.857IleTyr: 1.857 ± 0.463
0.0IleXaa: 0.0 ± 0.0
Lys
4.776LysAla: 4.776 ± 0.985
1.327LysCys: 1.327 ± 0.672
2.388LysAsp: 2.388 ± 0.732
2.653LysGlu: 2.653 ± 0.09
3.449LysPhe: 3.449 ± 0.313
2.919LysGly: 2.919 ± 1.001
1.061LysHis: 1.061 ± 0.06
2.919LysIle: 2.919 ± 1.001
2.123LysLys: 2.123 ± 1.076
3.715LysLeu: 3.715 ± 1.404
1.061LysMet: 1.061 ± 0.419
2.123LysAsn: 2.123 ± 0.597
2.388LysPro: 2.388 ± 0.253
0.796LysGln: 0.796 ± 0.075
1.592LysArg: 1.592 ± 0.15
3.184LysSer: 3.184 ± 0.657
2.123LysThr: 2.123 ± 0.597
4.245LysVal: 4.245 ± 1.195
1.327LysTrp: 1.327 ± 0.194
2.653LysTyr: 2.653 ± 0.09
0.0LysXaa: 0.0 ± 0.0
Leu
5.572LeuAla: 5.572 ± 1.003
1.857LeuCys: 1.857 ± 0.941
5.041LeuAsp: 5.041 ± 1.12
2.919LeuGlu: 2.919 ± 0.044
2.388LeuPhe: 2.388 ± 1.21
3.715LeuGly: 3.715 ± 0.987
2.388LeuHis: 2.388 ± 0.732
4.776LeuIle: 4.776 ± 1.942
3.98LeuLys: 3.98 ± 0.104
5.837LeuLeu: 5.837 ± 2.001
1.857LeuMet: 1.857 ± 0.972
5.572LeuAsn: 5.572 ± 1.481
4.776LeuPro: 4.776 ± 0.029
1.857LeuGln: 1.857 ± 0.494
4.245LeuArg: 4.245 ± 0.716
3.98LeuSer: 3.98 ± 1.06
5.572LeuThr: 5.572 ± 0.432
6.102LeuVal: 6.102 ± 2.136
0.796LeuTrp: 0.796 ± 0.075
2.388LeuTyr: 2.388 ± 0.703
0.0LeuXaa: 0.0 ± 0.0
Met
1.061MetAla: 1.061 ± 0.06
0.0MetCys: 0.0 ± 0.0
1.327MetAsp: 1.327 ± 0.284
1.327MetGlu: 1.327 ± 0.284
1.327MetPhe: 1.327 ± 0.194
2.919MetGly: 2.919 ± 1.391
1.327MetHis: 1.327 ± 1.241
0.796MetIle: 0.796 ± 0.403
1.592MetLys: 1.592 ± 0.15
1.327MetLeu: 1.327 ± 0.194
1.061MetMet: 1.061 ± 0.897
2.123MetAsn: 2.123 ± 0.359
1.592MetPro: 1.592 ± 0.15
1.061MetGln: 1.061 ± 0.897
1.592MetArg: 1.592 ± 0.328
3.98MetSer: 3.98 ± 1.331
1.327MetThr: 1.327 ± 0.284
1.061MetVal: 1.061 ± 0.538
0.265MetTrp: 0.265 ± 0.134
0.796MetTyr: 0.796 ± 0.403
0.0MetXaa: 0.0 ± 0.0
Asn
3.184AsnAla: 3.184 ± 0.3
0.531AsnCys: 0.531 ± 0.269
2.123AsnAsp: 2.123 ± 0.119
2.123AsnGlu: 2.123 ± 0.837
3.449AsnPhe: 3.449 ± 0.165
3.715AsnGly: 3.715 ± 1.466
0.0AsnHis: 0.0 ± 0.0
1.592AsnIle: 1.592 ± 0.15
2.388AsnLys: 2.388 ± 0.253
2.919AsnLeu: 2.919 ± 0.912
0.796AsnMet: 0.796 ± 0.075
2.919AsnAsn: 2.919 ± 0.044
2.919AsnPro: 2.919 ± 0.434
1.857AsnGln: 1.857 ± 0.463
3.449AsnArg: 3.449 ± 0.644
2.123AsnSer: 2.123 ± 0.837
4.51AsnThr: 4.51 ± 2.975
5.306AsnVal: 5.306 ± 0.181
1.061AsnTrp: 1.061 ± 0.897
1.061AsnTyr: 1.061 ± 0.06
0.0AsnXaa: 0.0 ± 0.0
Pro
5.306ProAla: 5.306 ± 2.094
0.265ProCys: 0.265 ± 0.134
3.449ProAsp: 3.449 ± 1.122
3.184ProGlu: 3.184 ± 0.657
3.184ProPhe: 3.184 ± 1.256
6.633ProGly: 6.633 ± 2.378
3.449ProHis: 3.449 ± 0.313
2.123ProIle: 2.123 ± 0.359
2.123ProLys: 2.123 ± 0.119
3.449ProLeu: 3.449 ± 0.644
1.327ProMet: 1.327 ± 0.194
2.123ProAsn: 2.123 ± 0.837
3.184ProPro: 3.184 ± 0.179
1.061ProGln: 1.061 ± 0.419
0.531ProArg: 0.531 ± 0.209
3.98ProSer: 3.98 ± 0.375
3.184ProThr: 3.184 ± 2.691
5.572ProVal: 5.572 ± 0.046
0.796ProTrp: 0.796 ± 0.403
1.592ProTyr: 1.592 ± 0.628
0.0ProXaa: 0.0 ± 0.0
Gln
3.449GlnAla: 3.449 ± 0.313
1.061GlnCys: 1.061 ± 0.538
1.061GlnAsp: 1.061 ± 0.06
1.061GlnGlu: 1.061 ± 0.419
1.327GlnPhe: 1.327 ± 0.194
1.592GlnGly: 1.592 ± 0.807
0.531GlnHis: 0.531 ± 0.269
2.388GlnIle: 2.388 ± 0.225
0.796GlnLys: 0.796 ± 0.403
2.388GlnLeu: 2.388 ± 0.225
0.796GlnMet: 0.796 ± 0.553
0.265GlnAsn: 0.265 ± 0.344
1.061GlnPro: 1.061 ± 0.897
0.796GlnGln: 0.796 ± 0.553
1.327GlnArg: 1.327 ± 0.763
3.98GlnSer: 3.98 ± 1.809
1.857GlnThr: 1.857 ± 0.972
2.388GlnVal: 2.388 ± 0.732
0.531GlnTrp: 0.531 ± 0.209
1.061GlnTyr: 1.061 ± 0.419
0.0GlnXaa: 0.0 ± 0.0
Arg
2.919ArgAla: 2.919 ± 1.001
0.531ArgCys: 0.531 ± 0.269
3.184ArgAsp: 3.184 ± 0.657
3.98ArgGlu: 3.98 ± 0.853
3.449ArgPhe: 3.449 ± 0.791
2.919ArgGly: 2.919 ± 0.912
1.857ArgHis: 1.857 ± 0.463
2.653ArgIle: 2.653 ± 0.09
1.857ArgLys: 1.857 ± 0.015
4.51ArgLeu: 4.51 ± 0.106
1.327ArgMet: 1.327 ± 0.194
1.857ArgAsn: 1.857 ± 0.972
2.123ArgPro: 2.123 ± 0.119
1.857ArgGln: 1.857 ± 0.015
2.123ArgArg: 2.123 ± 0.597
3.449ArgSer: 3.449 ± 0.313
2.919ArgThr: 2.919 ± 0.522
2.653ArgVal: 2.653 ± 0.09
0.796ArgTrp: 0.796 ± 0.075
2.919ArgTyr: 2.919 ± 0.522
0.0ArgXaa: 0.0 ± 0.0
Ser
7.429SerAla: 7.429 ± 0.54
1.592SerCys: 1.592 ± 0.15
5.572SerAsp: 5.572 ± 1.389
3.449SerGlu: 3.449 ± 0.791
4.245SerPhe: 4.245 ± 0.716
5.041SerGly: 5.041 ± 0.163
2.388SerHis: 2.388 ± 1.21
2.919SerIle: 2.919 ± 0.522
3.184SerLys: 3.184 ± 0.657
7.429SerLeu: 7.429 ± 1.018
1.592SerMet: 1.592 ± 1.106
5.837SerAsn: 5.837 ± 0.39
2.919SerPro: 2.919 ± 1.001
4.51SerGln: 4.51 ± 0.106
3.184SerArg: 3.184 ± 0.657
7.164SerSer: 7.164 ± 1.239
3.715SerThr: 3.715 ± 1.944
6.368SerVal: 6.368 ± 1.078
0.796SerTrp: 0.796 ± 0.075
2.388SerTyr: 2.388 ± 0.225
0.0SerXaa: 0.0 ± 0.0
Thr
3.715ThrAla: 3.715 ± 1.466
1.327ThrCys: 1.327 ± 0.672
1.857ThrAsp: 1.857 ± 0.494
2.123ThrGlu: 2.123 ± 0.837
3.715ThrPhe: 3.715 ± 0.447
3.98ThrGly: 3.98 ± 0.375
1.327ThrHis: 1.327 ± 0.284
2.919ThrIle: 2.919 ± 0.434
2.388ThrLys: 2.388 ± 0.732
4.776ThrLeu: 4.776 ± 0.507
1.327ThrMet: 1.327 ± 0.163
3.184ThrAsn: 3.184 ± 0.778
2.123ThrPro: 2.123 ± 0.837
1.592ThrGln: 1.592 ± 0.628
2.123ThrArg: 2.123 ± 0.359
4.776ThrSer: 4.776 ± 0.029
3.715ThrThr: 3.715 ± 0.987
4.776ThrVal: 4.776 ± 1.884
1.061ThrTrp: 1.061 ± 0.06
2.919ThrTyr: 2.919 ± 0.912
0.0ThrXaa: 0.0 ± 0.0
Val
6.368ValAla: 6.368 ± 0.121
0.796ValCys: 0.796 ± 0.403
4.776ValAsp: 4.776 ± 1.942
2.653ValGlu: 2.653 ± 0.09
4.51ValPhe: 4.51 ± 0.106
4.776ValGly: 4.776 ± 0.45
2.123ValHis: 2.123 ± 0.597
2.653ValIle: 2.653 ± 0.569
3.98ValLys: 3.98 ± 0.582
6.102ValLeu: 6.102 ± 0.223
2.653ValMet: 2.653 ± 0.866
3.98ValAsn: 3.98 ± 1.809
4.776ValPro: 4.776 ± 2.841
1.327ValGln: 1.327 ± 0.194
3.715ValArg: 3.715 ± 0.926
3.98ValSer: 3.98 ± 1.538
6.898ValThr: 6.898 ± 0.809
2.919ValVal: 2.919 ± 0.522
1.327ValTrp: 1.327 ± 0.672
2.388ValTyr: 2.388 ± 0.225
0.0ValXaa: 0.0 ± 0.0
Trp
1.857TrpAla: 1.857 ± 0.494
0.0TrpCys: 0.0 ± 0.0
1.327TrpAsp: 1.327 ± 0.672
0.796TrpGlu: 0.796 ± 0.403
0.796TrpPhe: 0.796 ± 0.553
0.265TrpGly: 0.265 ± 0.134
0.265TrpHis: 0.265 ± 0.134
0.531TrpIle: 0.531 ± 0.269
1.327TrpLys: 1.327 ± 0.672
1.061TrpLeu: 1.061 ± 0.419
0.531TrpMet: 0.531 ± 0.688
0.531TrpAsn: 0.531 ± 0.209
0.796TrpPro: 0.796 ± 0.075
1.327TrpGln: 1.327 ± 0.194
1.592TrpArg: 1.592 ± 0.15
1.327TrpSer: 1.327 ± 0.284
0.0TrpThr: 0.0 ± 0.0
0.796TrpVal: 0.796 ± 0.075
0.796TrpTrp: 0.796 ± 0.403
0.0TrpTyr: 0.0 ± 0.0
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.653TyrAla: 2.653 ± 0.388
0.796TyrCys: 0.796 ± 0.075
2.388TyrAsp: 2.388 ± 0.703
2.123TyrGlu: 2.123 ± 0.597
1.857TyrPhe: 1.857 ± 0.494
3.449TyrGly: 3.449 ± 1.122
0.531TyrHis: 0.531 ± 0.269
2.653TyrIle: 2.653 ± 0.388
1.061TyrLys: 1.061 ± 0.538
2.123TyrLeu: 2.123 ± 0.119
0.796TyrMet: 0.796 ± 0.075
1.061TyrAsn: 1.061 ± 0.06
2.919TyrPro: 2.919 ± 0.912
1.061TyrGln: 1.061 ± 0.06
2.653TyrArg: 2.653 ± 0.569
2.388TyrSer: 2.388 ± 0.732
1.592TyrThr: 1.592 ± 0.328
2.653TyrVal: 2.653 ± 0.09
0.796TyrTrp: 0.796 ± 0.075
1.327TyrTyr: 1.327 ± 0.194
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 2 proteins (3770 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski