Amino acid dipepetide frequency for Ceratocystis fimbriata CBS 114723

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	10.316AlaAla: 10.316 ± 0.104	1.031AlaCys: 1.031 ± 0.019	4.387AlaAsp: 4.387 ± 0.039	5.319AlaGlu: 5.319 ± 0.084	2.935AlaPhe: 2.935 ± 0.033	5.472AlaGly: 5.472 ± 0.048	1.876AlaHis: 1.876 ± 0.023	4.271AlaIle: 4.271 ± 0.039	4.322AlaLys: 4.322 ± 0.037	7.641AlaLeu: 7.641 ± 0.058	2.305AlaMet: 2.305 ± 0.026	3.219AlaAsn: 3.219 ± 0.028	5.488AlaPro: 5.488 ± 0.057	3.656AlaGln: 3.656 ± 0.051	4.898AlaArg: 4.898 ± 0.042	8.822AlaSer: 8.822 ± 0.064	6.114AlaThr: 6.114 ± 0.051	5.506AlaVal: 5.506 ± 0.045	0.958AlaTrp: 0.958 ± 0.02	1.985AlaTyr: 1.985 ± 0.023	0.0AlaXaa: 0.0 ± 0.0
Cys	0.818CysAla: 0.818 ± 0.016	0.206CysCys: 0.206 ± 0.009	0.652CysAsp: 0.652 ± 0.014	0.603CysGlu: 0.603 ± 0.013	0.482CysPhe: 0.482 ± 0.012	0.847CysGly: 0.847 ± 0.02	0.321CysHis: 0.321 ± 0.009	0.661CysIle: 0.661 ± 0.012	0.494CysLys: 0.494 ± 0.014	1.208CysLeu: 1.208 ± 0.023	0.282CysMet: 0.282 ± 0.009	0.445CysAsn: 0.445 ± 0.011	0.611CysPro: 0.611 ± 0.013	0.434CysGln: 0.434 ± 0.012	0.679CysArg: 0.679 ± 0.015	0.934CysSer: 0.934 ± 0.019	0.66CysThr: 0.66 ± 0.013	0.714CysVal: 0.714 ± 0.014	0.159CysTrp: 0.159 ± 0.007	0.302CysTyr: 0.302 ± 0.009	0.0CysXaa: 0.0 ± 0.0
Asp	4.791AspAla: 4.791 ± 0.038	0.628AspCys: 0.628 ± 0.014	4.559AspAsp: 4.559 ± 0.06	4.459AspGlu: 4.459 ± 0.046	2.149AspPhe: 2.149 ± 0.022	3.912AspGly: 3.912 ± 0.037	1.211AspHis: 1.211 ± 0.021	3.141AspIle: 3.141 ± 0.032	2.494AspLys: 2.494 ± 0.033	4.792AspLeu: 4.792 ± 0.037	1.474AspMet: 1.474 ± 0.019	2.064AspAsn: 2.064 ± 0.028	3.09AspPro: 3.09 ± 0.031	1.793AspGln: 1.793 ± 0.025	2.98AspArg: 2.98 ± 0.049	4.778AspSer: 4.778 ± 0.048	2.95AspThr: 2.95 ± 0.029	3.595AspVal: 3.595 ± 0.035	0.727AspTrp: 0.727 ± 0.015	1.521AspTyr: 1.521 ± 0.022	0.001AspXaa: 0.001 ± 0.0
Glu	5.829GluAla: 5.829 ± 0.068	0.598GluCys: 0.598 ± 0.012	4.104GluAsp: 4.104 ± 0.046	5.004GluGlu: 5.004 ± 0.074	1.908GluPhe: 1.908 ± 0.026	3.195GluGly: 3.195 ± 0.029	1.223GluHis: 1.223 ± 0.019	3.046GluIle: 3.046 ± 0.031	3.597GluLys: 3.597 ± 0.036	4.875GluLeu: 4.875 ± 0.041	1.546GluMet: 1.546 ± 0.019	2.44GluAsn: 2.44 ± 0.026	2.804GluPro: 2.804 ± 0.063	2.233GluGln: 2.233 ± 0.031	3.608GluArg: 3.608 ± 0.045	4.509GluSer: 4.509 ± 0.045	3.554GluThr: 3.554 ± 0.036	3.295GluVal: 3.295 ± 0.035	0.789GluTrp: 0.789 ± 0.017	1.557GluTyr: 1.557 ± 0.023	0.0GluXaa: 0.0 ± 0.0
Phe	2.822PheAla: 2.822 ± 0.032	0.516PheCys: 0.516 ± 0.012	2.143PheAsp: 2.143 ± 0.028	1.977PheGlu: 1.977 ± 0.027	1.461PhePhe: 1.461 ± 0.025	2.49PheGly: 2.49 ± 0.035	0.841PheHis: 0.841 ± 0.014	1.628PheIle: 1.628 ± 0.022	1.487PheLys: 1.487 ± 0.02	3.035PheLeu: 3.035 ± 0.029	0.822PheMet: 0.822 ± 0.015	1.395PheAsn: 1.395 ± 0.019	1.796PhePro: 1.796 ± 0.023	1.266PheGln: 1.266 ± 0.018	1.82PheArg: 1.82 ± 0.021	3.152PheSer: 3.152 ± 0.03	1.953PheThr: 1.953 ± 0.025	2.23PheVal: 2.23 ± 0.025	0.512PheTrp: 0.512 ± 0.013	0.961PheTyr: 0.961 ± 0.017	0.0PheXaa: 0.0 ± 0.0
Gly	5.077GlyAla: 5.077 ± 0.049	0.744GlyCys: 0.744 ± 0.015	3.399GlyAsp: 3.399 ± 0.034	3.104GlyGlu: 3.104 ± 0.027	2.466GlyPhe: 2.466 ± 0.027	5.206GlyGly: 5.206 ± 0.067	1.713GlyHis: 1.713 ± 0.028	3.231GlyIle: 3.231 ± 0.036	3.075GlyLys: 3.075 ± 0.031	5.627GlyLeu: 5.627 ± 0.045	1.576GlyMet: 1.576 ± 0.024	2.46GlyAsn: 2.46 ± 0.03	3.323GlyPro: 3.323 ± 0.044	2.386GlyGln: 2.386 ± 0.031	3.766GlyArg: 3.766 ± 0.034	6.194GlySer: 6.194 ± 0.055	3.686GlyThr: 3.686 ± 0.034	3.916GlyVal: 3.916 ± 0.034	0.925GlyTrp: 0.925 ± 0.017	1.827GlyTyr: 1.827 ± 0.022	0.0GlyXaa: 0.0 ± 0.0
His	1.796HisAla: 1.796 ± 0.023	0.287HisCys: 0.287 ± 0.009	1.387HisAsp: 1.387 ± 0.02	1.338HisGlu: 1.338 ± 0.022	0.804HisPhe: 0.804 ± 0.015	1.677HisGly: 1.677 ± 0.024	0.987HisHis: 0.987 ± 0.024	1.244HisIle: 1.244 ± 0.018	1.011HisLys: 1.011 ± 0.018	2.02HisLeu: 2.02 ± 0.023	0.613HisMet: 0.613 ± 0.013	0.992HisAsn: 0.992 ± 0.019	1.518HisPro: 1.518 ± 0.023	1.189HisGln: 1.189 ± 0.023	1.555HisArg: 1.555 ± 0.021	2.2HisSer: 2.2 ± 0.029	1.359HisThr: 1.359 ± 0.019	1.451HisVal: 1.451 ± 0.022	0.266HisTrp: 0.266 ± 0.009	0.671HisTyr: 0.671 ± 0.012	0.0HisXaa: 0.0 ± 0.0
Ile	4.147IleAla: 4.147 ± 0.036	0.659IleCys: 0.659 ± 0.013	3.049IleAsp: 3.049 ± 0.029	2.976IleGlu: 2.976 ± 0.029	1.788IlePhe: 1.788 ± 0.023	2.845IleGly: 2.845 ± 0.03	1.157IleHis: 1.157 ± 0.017	2.378IleIle: 2.378 ± 0.029	2.359IleLys: 2.359 ± 0.03	4.116IleLeu: 4.116 ± 0.041	1.178IleMet: 1.178 ± 0.017	1.91IleAsn: 1.91 ± 0.025	3.033IlePro: 3.033 ± 0.034	1.808IleGln: 1.808 ± 0.023	2.713IleArg: 2.713 ± 0.03	4.352IleSer: 4.352 ± 0.038	2.794IleThr: 2.794 ± 0.027	3.02IleVal: 3.02 ± 0.033	0.692IleTrp: 0.692 ± 0.02	1.246IleTyr: 1.246 ± 0.016	0.0IleXaa: 0.0 ± 0.0
Lys	4.668LysAla: 4.668 ± 0.043	0.49LysCys: 0.49 ± 0.013	2.675LysAsp: 2.675 ± 0.03	3.085LysGlu: 3.085 ± 0.035	1.415LysPhe: 1.415 ± 0.024	2.652LysGly: 2.652 ± 0.028	1.118LysHis: 1.118 ± 0.017	2.425LysIle: 2.425 ± 0.029	3.505LysLys: 3.505 ± 0.047	4.063LysLeu: 4.063 ± 0.035	1.152LysMet: 1.152 ± 0.019	1.887LysAsn: 1.887 ± 0.025	2.926LysPro: 2.926 ± 0.03	1.839LysGln: 1.839 ± 0.024	3.336LysArg: 3.336 ± 0.035	3.749LysSer: 3.749 ± 0.038	3.171LysThr: 3.171 ± 0.031	2.68LysVal: 2.68 ± 0.031	0.609LysTrp: 0.609 ± 0.014	1.269LysTyr: 1.269 ± 0.019	0.001LysXaa: 0.001 ± 0.0
Leu	7.96LeuAla: 7.96 ± 0.057	1.135LeuCys: 1.135 ± 0.023	5.054LeuAsp: 5.054 ± 0.041	5.383LeuGlu: 5.383 ± 0.042	2.872LeuPhe: 2.872 ± 0.035	5.345LeuGly: 5.345 ± 0.038	2.054LeuHis: 2.054 ± 0.026	3.58LeuIle: 3.58 ± 0.039	4.089LeuLys: 4.089 ± 0.039	7.43LeuLeu: 7.43 ± 0.067	1.85LeuMet: 1.85 ± 0.025	3.113LeuAsn: 3.113 ± 0.03	5.339LeuPro: 5.339 ± 0.045	3.725LeuGln: 3.725 ± 0.038	5.513LeuArg: 5.513 ± 0.045	7.38LeuSer: 7.38 ± 0.044	4.492LeuThr: 4.492 ± 0.035	5.193LeuVal: 5.193 ± 0.05	1.053LeuTrp: 1.053 ± 0.018	2.115LeuTyr: 2.115 ± 0.027	0.001LeuXaa: 0.001 ± 0.0
Met	2.627MetAla: 2.627 ± 0.031	0.263MetCys: 0.263 ± 0.009	1.365MetAsp: 1.365 ± 0.021	1.376MetGlu: 1.376 ± 0.021	0.818MetPhe: 0.818 ± 0.016	1.58MetGly: 1.58 ± 0.023	0.556MetHis: 0.556 ± 0.013	0.997MetIle: 0.997 ± 0.018	1.024MetLys: 1.024 ± 0.016	1.998MetLeu: 1.998 ± 0.026	0.665MetMet: 0.665 ± 0.016	0.863MetAsn: 0.863 ± 0.016	1.554MetPro: 1.554 ± 0.023	0.954MetGln: 0.954 ± 0.018	1.386MetArg: 1.386 ± 0.02	2.226MetSer: 2.226 ± 0.026	1.456MetThr: 1.456 ± 0.02	1.384MetVal: 1.384 ± 0.023	0.259MetTrp: 0.259 ± 0.008	0.589MetTyr: 0.589 ± 0.011	0.0MetXaa: 0.0 ± 0.0
Asn	3.184AsnAla: 3.184 ± 0.029	0.441AsnCys: 0.441 ± 0.013	2.244AsnAsp: 2.244 ± 0.029	2.095AsnGlu: 2.095 ± 0.027	1.337AsnPhe: 1.337 ± 0.02	2.855AsnGly: 2.855 ± 0.028	0.922AsnHis: 0.922 ± 0.016	2.127AsnIle: 2.127 ± 0.026	1.718AsnLys: 1.718 ± 0.021	3.145AsnLeu: 3.145 ± 0.03	1.026AsnMet: 1.026 ± 0.019	1.833AsnAsn: 1.833 ± 0.027	2.485AsnPro: 2.485 ± 0.03	1.354AsnGln: 1.354 ± 0.019	2.008AsnArg: 2.008 ± 0.025	3.455AsnSer: 3.455 ± 0.032	2.49AsnThr: 2.49 ± 0.032	2.224AsnVal: 2.224 ± 0.027	0.505AsnTrp: 0.505 ± 0.012	1.037AsnTyr: 1.037 ± 0.016	0.0AsnXaa: 0.0 ± 0.0
Pro	5.819ProAla: 5.819 ± 0.068	0.528ProCys: 0.528 ± 0.013	3.079ProAsp: 3.079 ± 0.03	3.755ProGlu: 3.755 ± 0.036	1.875ProPhe: 1.875 ± 0.027	3.745ProGly: 3.745 ± 0.041	1.463ProHis: 1.463 ± 0.023	2.734ProIle: 2.734 ± 0.03	2.733ProLys: 2.733 ± 0.032	4.782ProLeu: 4.782 ± 0.048	1.321ProMet: 1.321 ± 0.023	2.245ProAsn: 2.245 ± 0.025	5.602ProPro: 5.602 ± 0.084	2.675ProGln: 2.675 ± 0.042	3.425ProArg: 3.425 ± 0.036	6.791ProSer: 6.791 ± 0.066	4.392ProThr: 4.392 ± 0.043	3.774ProVal: 3.774 ± 0.035	0.594ProTrp: 0.594 ± 0.013	1.36ProTyr: 1.36 ± 0.024	0.001ProXaa: 0.001 ± 0.0
Gln	3.764GlnAla: 3.764 ± 0.049	0.425GlnCys: 0.425 ± 0.01	2.017GlnAsp: 2.017 ± 0.025	2.244GlnGlu: 2.244 ± 0.027	1.174GlnPhe: 1.174 ± 0.017	2.106GlnGly: 2.106 ± 0.025	1.205GlnHis: 1.205 ± 0.022	1.875GlnIle: 1.875 ± 0.023	1.967GlnLys: 1.967 ± 0.023	3.32GlnLeu: 3.32 ± 0.037	0.976GlnMet: 0.976 ± 0.018	1.669GlnAsn: 1.669 ± 0.023	2.76GlnPro: 2.76 ± 0.042	3.161GlnGln: 3.161 ± 0.096	2.693GlnArg: 2.693 ± 0.036	3.385GlnSer: 3.385 ± 0.037	2.51GlnThr: 2.51 ± 0.031	2.079GlnVal: 2.079 ± 0.023	0.492GlnTrp: 0.492 ± 0.011	1.073GlnTyr: 1.073 ± 0.02	0.001GlnXaa: 0.001 ± 0.0
Arg	4.687ArgAla: 4.687 ± 0.038	0.668ArgCys: 0.668 ± 0.014	3.418ArgAsp: 3.418 ± 0.052	3.628ArgGlu: 3.628 ± 0.043	2.036ArgPhe: 2.036 ± 0.027	3.509ArgGly: 3.509 ± 0.046	1.584ArgHis: 1.584 ± 0.024	2.849ArgIle: 2.849 ± 0.034	3.412ArgLys: 3.412 ± 0.04	5.285ArgLeu: 5.285 ± 0.038	1.419ArgMet: 1.419 ± 0.02	2.39ArgAsn: 2.39 ± 0.029	3.55ArgPro: 3.55 ± 0.037	2.583ArgGln: 2.583 ± 0.031	4.975ArgArg: 4.975 ± 0.049	5.087ArgSer: 5.087 ± 0.058	3.164ArgThr: 3.164 ± 0.031	3.182ArgVal: 3.182 ± 0.031	0.753ArgTrp: 0.753 ± 0.013	1.51ArgTyr: 1.51 ± 0.02	0.001ArgXaa: 0.001 ± 0.0
Ser	7.929SerAla: 7.929 ± 0.061	0.879SerCys: 0.879 ± 0.02	4.634SerAsp: 4.634 ± 0.04	4.424SerGlu: 4.424 ± 0.04	3.091SerPhe: 3.091 ± 0.029	6.152SerGly: 6.152 ± 0.054	2.419SerHis: 2.419 ± 0.031	4.278SerIle: 4.278 ± 0.037	4.06SerLys: 4.06 ± 0.036	7.643SerLeu: 7.643 ± 0.051	2.039SerMet: 2.039 ± 0.024	3.53SerAsn: 3.53 ± 0.041	6.376SerPro: 6.376 ± 0.062	3.859SerGln: 3.859 ± 0.042	5.554SerArg: 5.554 ± 0.062	11.17SerSer: 11.17 ± 0.11	6.496SerThr: 6.496 ± 0.061	5.054SerVal: 5.054 ± 0.045	0.988SerTrp: 0.988 ± 0.019	2.058SerTyr: 2.058 ± 0.025	0.0SerXaa: 0.0 ± 0.0
Thr	5.899ThrAla: 5.899 ± 0.051	0.693ThrCys: 0.693 ± 0.016	2.904ThrAsp: 2.904 ± 0.036	3.206ThrGlu: 3.206 ± 0.036	1.923ThrPhe: 1.923 ± 0.021	4.034ThrGly: 4.034 ± 0.041	1.376ThrHis: 1.376 ± 0.021	3.038ThrIle: 3.038 ± 0.033	2.756ThrLys: 2.756 ± 0.033	5.091ThrLeu: 5.091 ± 0.04	1.322ThrMet: 1.322 ± 0.021	2.252ThrAsn: 2.252 ± 0.025	4.841ThrPro: 4.841 ± 0.05	2.247ThrGln: 2.247 ± 0.027	3.235ThrArg: 3.235 ± 0.027	6.321ThrSer: 6.321 ± 0.064	4.815ThrThr: 4.815 ± 0.052	3.668ThrVal: 3.668 ± 0.036	0.693ThrTrp: 0.693 ± 0.015	1.428ThrTyr: 1.428 ± 0.024	0.0ThrXaa: 0.0 ± 0.0
Val	5.451ValAla: 5.451 ± 0.042	0.804ValCys: 0.804 ± 0.015	3.527ValAsp: 3.527 ± 0.03	3.566ValGlu: 3.566 ± 0.05	2.346ValPhe: 2.346 ± 0.029	3.503ValGly: 3.503 ± 0.032	1.344ValHis: 1.344 ± 0.018	2.784ValIle: 2.784 ± 0.035	2.843ValLys: 2.843 ± 0.031	5.205ValLeu: 5.205 ± 0.043	1.395ValMet: 1.395 ± 0.02	2.144ValAsn: 2.144 ± 0.025	3.779ValPro: 3.779 ± 0.042	2.275ValGln: 2.275 ± 0.027	3.28ValArg: 3.28 ± 0.035	5.146ValSer: 5.146 ± 0.04	3.464ValThr: 3.464 ± 0.038	4.205ValVal: 4.205 ± 0.04	0.744ValTrp: 0.744 ± 0.018	1.62ValTyr: 1.62 ± 0.018	0.0ValXaa: 0.0 ± 0.0
Trp	1.005TrpAla: 1.005 ± 0.018	0.162TrpCys: 0.162 ± 0.007	0.899TrpAsp: 0.899 ± 0.023	0.74TrpGlu: 0.74 ± 0.014	0.427TrpPhe: 0.427 ± 0.012	0.734TrpGly: 0.734 ± 0.016	0.286TrpHis: 0.286 ± 0.01	0.665TrpIle: 0.665 ± 0.014	0.704TrpLys: 0.704 ± 0.013	1.092TrpLeu: 1.092 ± 0.017	0.351TrpMet: 0.351 ± 0.011	0.531TrpAsn: 0.531 ± 0.012	0.511TrpPro: 0.511 ± 0.013	0.449TrpGln: 0.449 ± 0.011	0.776TrpArg: 0.776 ± 0.016	0.895TrpSer: 0.895 ± 0.019	0.732TrpThr: 0.732 ± 0.016	0.765TrpVal: 0.765 ± 0.014	0.219TrpTrp: 0.219 ± 0.009	0.342TrpTyr: 0.342 ± 0.01	0.0TrpXaa: 0.0 ± 0.0
Tyr	1.933TyrAla: 1.933 ± 0.026	0.356TyrCys: 0.356 ± 0.011	1.614TyrAsp: 1.614 ± 0.025	1.431TyrGlu: 1.431 ± 0.02	0.999TyrPhe: 0.999 ± 0.016	1.842TyrGly: 1.842 ± 0.026	0.711TyrHis: 0.711 ± 0.014	1.269TyrIle: 1.269 ± 0.021	1.063TyrLys: 1.063 ± 0.016	2.308TyrLeu: 2.308 ± 0.028	0.631TyrMet: 0.631 ± 0.014	1.101TyrAsn: 1.101 ± 0.018	1.309TyrPro: 1.309 ± 0.019	1.013TyrGln: 1.013 ± 0.017	1.486TyrArg: 1.486 ± 0.018	2.085TyrSer: 2.085 ± 0.026	1.487TyrThr: 1.487 ± 0.023	1.49TyrVal: 1.49 ± 0.019	0.347TyrTrp: 0.347 ± 0.01	0.827TyrTyr: 0.827 ± 0.019	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.001XaaPhe: 0.001 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.001XaaLeu: 0.001 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.001XaaAsn: 0.001 ± 0.0	0.001XaaPro: 0.001 ± 0.0	0.001XaaGln: 0.001 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.001XaaSer: 0.001 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.001XaaVal: 0.001 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.067XaaXaa: 0.067 ± 0.026

Statistics based on 7264 proteins (3783215 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

---