Amino acid dipepetide frequency for Trematomus bernacchii polyomavirus 1

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
11.311AlaAla: 11.311 ± 5.987
1.996AlaCys: 1.996 ± 1.369
5.323AlaAsp: 5.323 ± 2.073
5.323AlaGlu: 5.323 ± 3.163
1.996AlaPhe: 1.996 ± 0.97
9.315AlaGly: 9.315 ± 4.335
2.661AlaHis: 2.661 ± 2.523
3.992AlaIle: 3.992 ± 0.926
3.327AlaLys: 3.327 ± 2.009
6.653AlaLeu: 6.653 ± 2.616
1.331AlaMet: 1.331 ± 1.695
1.331AlaAsn: 1.331 ± 0.421
4.657AlaPro: 4.657 ± 0.485
3.992AlaGln: 3.992 ± 1.262
2.661AlaArg: 2.661 ± 0.841
7.319AlaSer: 7.319 ± 1.685
2.661AlaThr: 2.661 ± 1.825
7.984AlaVal: 7.984 ± 2.829
1.996AlaTrp: 1.996 ± 1.163
0.665AlaTyr: 0.665 ± 0.695
0.0AlaXaa: 0.0 ± 0.0
Cys
0.0CysAla: 0.0 ± 0.0
0.0CysCys: 0.0 ± 0.0
0.665CysAsp: 0.665 ± 0.456
0.0CysGlu: 0.0 ± 0.0
1.996CysPhe: 1.996 ± 0.967
0.665CysGly: 0.665 ± 0.456
0.0CysHis: 0.0 ± 0.0
0.0CysIle: 0.0 ± 0.0
1.331CysLys: 1.331 ± 0.913
2.661CysLeu: 2.661 ± 1.825
0.665CysMet: 0.665 ± 0.456
1.996CysAsn: 1.996 ± 1.369
1.331CysPro: 1.331 ± 0.708
0.665CysGln: 0.665 ± 0.456
1.331CysArg: 1.331 ± 0.913
0.665CysSer: 0.665 ± 0.695
1.331CysThr: 1.331 ± 0.913
3.327CysVal: 3.327 ± 1.748
0.0CysTrp: 0.0 ± 0.0
2.661CysTyr: 2.661 ± 1.995
0.0CysXaa: 0.0 ± 0.0
Asp
4.657AspAla: 4.657 ± 1.557
2.661AspCys: 2.661 ± 1.825
3.327AspAsp: 3.327 ± 1.419
3.992AspGlu: 3.992 ± 1.86
3.327AspPhe: 3.327 ± 1.632
4.657AspGly: 4.657 ± 0.649
0.665AspHis: 0.665 ± 0.631
1.331AspIle: 1.331 ± 0.721
1.996AspLys: 1.996 ± 0.61
10.645AspLeu: 10.645 ± 1.654
0.665AspMet: 0.665 ± 0.631
1.331AspAsn: 1.331 ± 0.721
2.661AspPro: 2.661 ± 0.337
2.661AspGln: 2.661 ± 0.841
3.992AspArg: 3.992 ± 1.86
1.331AspSer: 1.331 ± 0.708
1.996AspThr: 1.996 ± 1.163
3.992AspVal: 3.992 ± 1.22
0.0AspTrp: 0.0 ± 0.0
1.331AspTyr: 1.331 ± 0.421
0.0AspXaa: 0.0 ± 0.0
Glu
4.657GluAla: 4.657 ± 0.918
1.996GluCys: 1.996 ± 0.967
4.657GluAsp: 4.657 ± 1.583
5.323GluGlu: 5.323 ± 0.633
1.331GluPhe: 1.331 ± 0.421
5.988GluGly: 5.988 ± 1.868
2.661GluHis: 2.661 ± 0.337
2.661GluIle: 2.661 ± 0.715
2.661GluLys: 2.661 ± 0.992
3.327GluLeu: 3.327 ± 0.943
1.996GluMet: 1.996 ± 0.61
1.331GluAsn: 1.331 ± 0.708
3.327GluPro: 3.327 ± 1.308
0.665GluGln: 0.665 ± 0.456
2.661GluArg: 2.661 ± 0.715
4.657GluSer: 4.657 ± 0.699
5.323GluThr: 5.323 ± 0.633
5.323GluVal: 5.323 ± 1.248
0.665GluTrp: 0.665 ± 0.456
1.996GluTyr: 1.996 ± 1.893
0.0GluXaa: 0.0 ± 0.0
Phe
3.327PheAla: 3.327 ± 1.419
0.0PheCys: 0.0 ± 0.0
0.0PheAsp: 0.0 ± 0.0
3.327PheGlu: 3.327 ± 1.419
2.661PhePhe: 2.661 ± 0.337
2.661PheGly: 2.661 ± 1.415
1.996PheHis: 1.996 ± 1.369
1.331PheIle: 1.331 ± 0.708
1.996PheLys: 1.996 ± 0.329
2.661PheLeu: 2.661 ± 1.825
0.665PheMet: 0.665 ± 0.456
1.996PheAsn: 1.996 ± 0.61
1.996PhePro: 1.996 ± 0.967
3.327PheGln: 3.327 ± 0.732
2.661PheArg: 2.661 ± 1.337
3.327PheSer: 3.327 ± 2.204
3.327PheThr: 3.327 ± 1.693
0.665PheVal: 0.665 ± 0.631
0.0PheTrp: 0.0 ± 0.0
0.665PheTyr: 0.665 ± 0.456
0.0PheXaa: 0.0 ± 0.0
Gly
3.992GlyAla: 3.992 ± 1.925
0.665GlyCys: 0.665 ± 0.456
5.323GlyAsp: 5.323 ± 1.431
5.988GlyGlu: 5.988 ± 1.053
5.323GlyPhe: 5.323 ± 2.673
3.327GlyGly: 3.327 ± 0.905
1.996GlyHis: 1.996 ± 0.61
5.988GlyIle: 5.988 ± 1.053
4.657GlyLys: 4.657 ± 2.322
3.992GlyLeu: 3.992 ± 0.658
1.331GlyMet: 1.331 ± 0.421
3.327GlyAsn: 3.327 ± 1.693
2.661GlyPro: 2.661 ± 0.337
1.996GlyGln: 1.996 ± 0.61
4.657GlyArg: 4.657 ± 1.758
4.657GlySer: 4.657 ± 1.32
5.988GlyThr: 5.988 ± 3.029
4.657GlyVal: 4.657 ± 1.876
0.665GlyTrp: 0.665 ± 0.456
6.653GlyTyr: 6.653 ± 1.601
0.0GlyXaa: 0.0 ± 0.0
His
1.996HisAla: 1.996 ± 0.61
0.0HisCys: 0.0 ± 0.0
0.665HisAsp: 0.665 ± 0.456
0.665HisGlu: 0.665 ± 0.456
1.331HisPhe: 1.331 ± 0.913
3.327HisGly: 3.327 ± 1.356
0.665HisHis: 0.665 ± 0.456
0.0HisIle: 0.0 ± 0.0
0.0HisLys: 0.0 ± 0.0
1.331HisLeu: 1.331 ± 0.421
0.665HisMet: 0.665 ± 0.456
0.0HisAsn: 0.0 ± 0.0
1.331HisPro: 1.331 ± 0.421
0.665HisGln: 0.665 ± 0.631
2.661HisArg: 2.661 ± 1.582
0.665HisSer: 0.665 ± 0.456
1.996HisThr: 1.996 ± 1.893
1.996HisVal: 1.996 ± 1.326
0.665HisTrp: 0.665 ± 0.631
1.331HisTyr: 1.331 ± 0.913
0.0HisXaa: 0.0 ± 0.0
Ile
1.331IleAla: 1.331 ± 1.262
0.0IleCys: 0.0 ± 0.0
3.327IleAsp: 3.327 ± 0.732
3.992IleGlu: 3.992 ± 1.925
2.661IlePhe: 2.661 ± 0.992
3.327IleGly: 3.327 ± 1.356
0.0IleHis: 0.0 ± 0.0
2.661IleIle: 2.661 ± 1.825
1.331IleLys: 1.331 ± 0.708
3.327IleLeu: 3.327 ± 0.296
1.331IleMet: 1.331 ± 0.721
1.996IleAsn: 1.996 ± 0.329
3.992IlePro: 3.992 ± 2.386
0.0IleGln: 0.0 ± 0.0
1.996IleArg: 1.996 ± 0.61
2.661IleSer: 2.661 ± 1.442
3.992IleThr: 3.992 ± 0.283
3.327IleVal: 3.327 ± 0.732
1.331IleTrp: 1.331 ± 0.721
0.665IleTyr: 0.665 ± 0.456
0.0IleXaa: 0.0 ± 0.0
Lys
2.661LysAla: 2.661 ± 0.992
0.665LysCys: 0.665 ± 0.695
1.331LysAsp: 1.331 ± 0.913
2.661LysGlu: 2.661 ± 0.841
0.665LysPhe: 0.665 ± 0.456
3.327LysGly: 3.327 ± 1.632
0.665LysHis: 0.665 ± 0.456
3.327LysIle: 3.327 ± 2.677
5.323LysLys: 5.323 ± 3.651
3.327LysLeu: 3.327 ± 2.009
1.331LysMet: 1.331 ± 0.615
2.661LysAsn: 2.661 ± 1.337
2.661LysPro: 2.661 ± 0.992
1.996LysGln: 1.996 ± 1.326
5.323LysArg: 5.323 ± 0.633
6.653LysSer: 6.653 ± 1.352
1.331LysThr: 1.331 ± 0.708
2.661LysVal: 2.661 ± 0.992
1.996LysTrp: 1.996 ± 1.326
2.661LysTyr: 2.661 ± 0.337
0.0LysXaa: 0.0 ± 0.0
Leu
8.649LeuAla: 8.649 ± 2.291
3.992LeuCys: 3.992 ± 2.738
5.988LeuAsp: 5.988 ± 0.064
1.996LeuGlu: 1.996 ± 0.61
2.661LeuPhe: 2.661 ± 0.715
6.653LeuGly: 6.653 ± 0.458
1.331LeuHis: 1.331 ± 0.421
1.331LeuIle: 1.331 ± 1.262
0.665LeuLys: 0.665 ± 0.456
5.988LeuLeu: 5.988 ± 2.06
3.992LeuMet: 3.992 ± 1.934
3.327LeuAsn: 3.327 ± 2.009
5.988LeuPro: 5.988 ± 0.987
1.996LeuGln: 1.996 ± 0.61
3.992LeuArg: 3.992 ± 1.22
3.992LeuSer: 3.992 ± 2.83
8.649LeuThr: 8.649 ± 0.777
3.327LeuVal: 3.327 ± 0.296
0.665LeuTrp: 0.665 ± 0.456
1.996LeuTyr: 1.996 ± 1.326
0.0LeuXaa: 0.0 ± 0.0
Met
2.661MetAla: 2.661 ± 0.841
0.665MetCys: 0.665 ± 0.695
1.331MetAsp: 1.331 ± 1.389
1.996MetGlu: 1.996 ± 1.267
0.665MetPhe: 0.665 ± 0.456
3.327MetGly: 3.327 ± 1.308
0.0MetHis: 0.0 ± 0.0
0.665MetIle: 0.665 ± 0.456
1.996MetLys: 1.996 ± 0.329
3.327MetLeu: 3.327 ± 1.356
0.0MetMet: 0.0 ± 0.0
0.665MetAsn: 0.665 ± 0.456
1.331MetPro: 1.331 ± 0.708
1.331MetGln: 1.331 ± 0.421
1.331MetArg: 1.331 ± 0.421
0.665MetSer: 0.665 ± 0.456
0.665MetThr: 0.665 ± 0.631
2.661MetVal: 2.661 ± 0.337
0.665MetTrp: 0.665 ± 0.456
0.0MetTyr: 0.0 ± 0.0
0.0MetXaa: 0.0 ± 0.0
Asn
2.661AsnAla: 2.661 ± 0.337
1.331AsnCys: 1.331 ± 0.708
4.657AsnAsp: 4.657 ± 1.621
1.331AsnGlu: 1.331 ± 1.389
0.665AsnPhe: 0.665 ± 0.456
1.331AsnGly: 1.331 ± 0.721
1.331AsnHis: 1.331 ± 0.708
3.327AsnIle: 3.327 ± 0.905
3.992AsnLys: 3.992 ± 2.652
0.665AsnLeu: 0.665 ± 0.456
0.665AsnMet: 0.665 ± 0.631
0.665AsnAsn: 0.665 ± 0.695
1.331AsnPro: 1.331 ± 0.721
3.327AsnGln: 3.327 ± 1.748
1.331AsnArg: 1.331 ± 1.262
2.661AsnSer: 2.661 ± 1.337
0.665AsnThr: 0.665 ± 0.695
1.996AsnVal: 1.996 ± 1.369
0.665AsnTrp: 0.665 ± 0.631
0.0AsnTyr: 0.0 ± 0.0
0.0AsnXaa: 0.0 ± 0.0
Pro
1.996ProAla: 1.996 ± 0.967
0.0ProCys: 0.0 ± 0.0
3.992ProAsp: 3.992 ± 1.262
5.988ProGlu: 5.988 ± 0.064
0.665ProPhe: 0.665 ± 0.695
5.323ProGly: 5.323 ± 0.463
0.0ProHis: 0.0 ± 0.0
1.996ProIle: 1.996 ± 0.97
5.323ProLys: 5.323 ± 0.463
3.327ProLeu: 3.327 ± 1.356
1.331ProMet: 1.331 ± 0.708
1.331ProAsn: 1.331 ± 1.389
3.992ProPro: 3.992 ± 1.578
3.327ProGln: 3.327 ± 1.023
1.331ProArg: 1.331 ± 0.721
6.653ProSer: 6.653 ± 3.264
1.331ProThr: 1.331 ± 0.421
6.653ProVal: 6.653 ± 2.435
1.331ProTrp: 1.331 ± 0.708
1.331ProTyr: 1.331 ± 0.708
0.0ProXaa: 0.0 ± 0.0
Gln
2.661GlnAla: 2.661 ± 0.715
1.331GlnCys: 1.331 ± 0.708
1.331GlnAsp: 1.331 ± 0.421
1.996GlnGlu: 1.996 ± 1.369
0.665GlnPhe: 0.665 ± 0.456
3.327GlnGly: 3.327 ± 0.905
1.331GlnHis: 1.331 ± 0.913
2.661GlnIle: 2.661 ± 0.715
0.665GlnLys: 0.665 ± 0.456
3.992GlnLeu: 3.992 ± 1.262
2.661GlnMet: 2.661 ± 1.442
1.996GlnAsn: 1.996 ± 0.61
1.996GlnPro: 1.996 ± 1.326
1.331GlnGln: 1.331 ± 0.721
2.661GlnArg: 2.661 ± 0.715
3.992GlnSer: 3.992 ± 1.934
1.996GlnThr: 1.996 ± 0.61
2.661GlnVal: 2.661 ± 1.002
0.0GlnTrp: 0.0 ± 0.0
0.665GlnTyr: 0.665 ± 0.695
0.0GlnXaa: 0.0 ± 0.0
Arg
5.323ArgAla: 5.323 ± 2.32
1.331ArgCys: 1.331 ± 0.913
2.661ArgAsp: 2.661 ± 0.337
3.992ArgGlu: 3.992 ± 1.262
1.331ArgPhe: 1.331 ± 0.913
3.327ArgGly: 3.327 ± 0.943
1.996ArgHis: 1.996 ± 0.61
1.996ArgIle: 1.996 ± 0.97
3.327ArgLys: 3.327 ± 0.943
4.657ArgLeu: 4.657 ± 1.557
1.331ArgMet: 1.331 ± 0.805
0.0ArgAsn: 0.0 ± 0.0
1.996ArgPro: 1.996 ± 0.61
2.661ArgGln: 2.661 ± 0.715
1.996ArgArg: 1.996 ± 1.893
5.323ArgSer: 5.323 ± 3.176
1.331ArgThr: 1.331 ± 1.262
1.996ArgVal: 1.996 ± 0.61
0.665ArgTrp: 0.665 ± 0.695
3.327ArgTyr: 3.327 ± 0.732
0.0ArgXaa: 0.0 ± 0.0
Ser
7.984SerAla: 7.984 ± 2.146
1.996SerCys: 1.996 ± 0.967
2.661SerAsp: 2.661 ± 0.841
3.327SerGlu: 3.327 ± 0.296
1.331SerPhe: 1.331 ± 0.421
7.984SerGly: 7.984 ± 0.917
0.0SerHis: 0.0 ± 0.0
3.327SerIle: 3.327 ± 1.748
3.992SerLys: 3.992 ± 1.025
4.657SerLeu: 4.657 ± 2.615
0.0SerMet: 0.0 ± 0.0
2.661SerAsn: 2.661 ± 0.337
5.323SerPro: 5.323 ± 1.338
2.661SerGln: 2.661 ± 1.002
3.327SerArg: 3.327 ± 2.325
9.315SerSer: 9.315 ± 2.28
5.988SerThr: 5.988 ± 1.855
4.657SerVal: 4.657 ± 1.557
1.331SerTrp: 1.331 ± 0.721
2.661SerTyr: 2.661 ± 1.415
0.0SerXaa: 0.0 ± 0.0
Thr
2.661ThrAla: 2.661 ± 2.523
1.331ThrCys: 1.331 ± 0.913
1.996ThrAsp: 1.996 ± 0.967
5.323ThrGlu: 5.323 ± 2.188
1.996ThrPhe: 1.996 ± 0.61
3.327ThrGly: 3.327 ± 2.009
1.996ThrHis: 1.996 ± 0.97
1.331ThrIle: 1.331 ± 0.708
1.331ThrLys: 1.331 ± 0.913
4.657ThrLeu: 4.657 ± 0.649
2.661ThrMet: 2.661 ± 1.727
2.661ThrAsn: 2.661 ± 1.337
4.657ThrPro: 4.657 ± 0.699
3.992ThrGln: 3.992 ± 2.386
3.327ThrArg: 3.327 ± 1.356
3.992ThrSer: 3.992 ± 2.162
2.661ThrThr: 2.661 ± 0.715
5.988ThrVal: 5.988 ± 1.868
0.0ThrTrp: 0.0 ± 0.0
2.661ThrTyr: 2.661 ± 1.582
0.0ThrXaa: 0.0 ± 0.0
Val
14.637ValAla: 14.637 ± 6.243
0.665ValCys: 0.665 ± 0.456
5.988ValAsp: 5.988 ± 2.405
2.661ValGlu: 2.661 ± 0.992
3.992ValPhe: 3.992 ± 1.172
3.327ValGly: 3.327 ± 1.023
1.996ValHis: 1.996 ± 0.97
1.996ValIle: 1.996 ± 1.893
6.653ValLys: 6.653 ± 2.271
5.988ValLeu: 5.988 ± 1.925
0.665ValMet: 0.665 ± 0.631
3.327ValAsn: 3.327 ± 1.632
3.992ValPro: 3.992 ± 1.172
1.996ValGln: 1.996 ± 0.967
1.331ValArg: 1.331 ± 1.262
4.657ValSer: 4.657 ± 1.591
3.327ValThr: 3.327 ± 1.308
4.657ValVal: 4.657 ± 1.32
0.0ValTrp: 0.0 ± 0.0
0.0ValTyr: 0.0 ± 0.0
0.0ValXaa: 0.0 ± 0.0
Trp
0.0TrpAla: 0.0 ± 0.0
0.665TrpCys: 0.665 ± 0.695
0.0TrpAsp: 0.0 ± 0.0
0.665TrpGlu: 0.665 ± 0.695
0.0TrpPhe: 0.0 ± 0.0
1.331TrpGly: 1.331 ± 0.708
0.0TrpHis: 0.0 ± 0.0
0.665TrpIle: 0.665 ± 0.456
0.0TrpLys: 0.0 ± 0.0
0.665TrpLeu: 0.665 ± 0.695
1.996TrpMet: 1.996 ± 0.967
1.331TrpAsn: 1.331 ± 1.262
1.331TrpPro: 1.331 ± 0.721
0.0TrpGln: 0.0 ± 0.0
0.0TrpArg: 0.0 ± 0.0
0.665TrpSer: 0.665 ± 0.631
1.331TrpThr: 1.331 ± 0.421
1.331TrpVal: 1.331 ± 0.708
0.0TrpTrp: 0.0 ± 0.0
0.665TrpTyr: 0.665 ± 0.631
0.0TrpXaa: 0.0 ± 0.0
Tyr
3.992TyrAla: 3.992 ± 1.025
0.0TyrCys: 0.0 ± 0.0
1.996TyrAsp: 1.996 ± 1.163
2.661TyrGlu: 2.661 ± 0.337
3.327TyrPhe: 3.327 ± 1.023
1.996TyrGly: 1.996 ± 0.61
0.665TyrHis: 0.665 ± 0.631
2.661TyrIle: 2.661 ± 0.337
2.661TyrLys: 2.661 ± 1.415
1.331TyrLeu: 1.331 ± 0.708
0.0TyrMet: 0.0 ± 0.0
0.665TyrAsn: 0.665 ± 0.695
0.665TyrPro: 0.665 ± 0.456
1.331TyrGln: 1.331 ± 0.708
1.996TyrArg: 1.996 ± 1.369
1.331TyrSer: 1.331 ± 1.262
2.661TyrThr: 2.661 ± 0.715
1.996TyrVal: 1.996 ± 1.163
0.0TyrTrp: 0.0 ± 0.0
1.331TyrTyr: 1.331 ± 0.721
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 3 proteins (1504 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski