Amino acid dipepetide frequency for Hubei diptera virus 11

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
2.238AlaAla: 2.238 ± 0.88
0.56AlaCys: 0.56 ± 0.457
0.56AlaAsp: 0.56 ± 0.29
3.358AlaGlu: 3.358 ± 0.948
2.238AlaPhe: 2.238 ± 0.381
0.839AlaGly: 0.839 ± 0.383
0.839AlaHis: 0.839 ± 0.336
2.798AlaIle: 2.798 ± 1.065
1.119AlaLys: 1.119 ± 0.639
3.637AlaLeu: 3.637 ± 0.81
0.56AlaMet: 0.56 ± 0.32
1.959AlaAsn: 1.959 ± 0.384
1.119AlaPro: 1.119 ± 0.627
1.959AlaGln: 1.959 ± 0.588
0.839AlaArg: 0.839 ± 0.336
1.959AlaSer: 1.959 ± 0.544
2.238AlaThr: 2.238 ± 0.986
3.078AlaVal: 3.078 ± 0.714
0.28AlaTrp: 0.28 ± 0.365
2.518AlaTyr: 2.518 ± 0.851
0.0AlaXaa: 0.0 ± 0.0
Cys
0.28CysAla: 0.28 ± 0.145
0.0CysCys: 0.0 ± 0.0
0.28CysAsp: 0.28 ± 0.145
0.56CysGlu: 0.56 ± 0.654
1.679CysPhe: 1.679 ± 0.534
1.119CysGly: 1.119 ± 0.636
1.119CysHis: 1.119 ± 0.407
1.119CysIle: 1.119 ± 0.274
0.0CysLys: 0.0 ± 0.0
2.518CysLeu: 2.518 ± 0.69
0.28CysMet: 0.28 ± 0.327
1.119CysAsn: 1.119 ± 0.296
2.238CysPro: 2.238 ± 0.378
0.56CysGln: 0.56 ± 0.242
0.56CysArg: 0.56 ± 0.242
0.839CysSer: 0.839 ± 0.228
1.679CysThr: 1.679 ± 0.423
0.28CysVal: 0.28 ± 0.145
0.28CysTrp: 0.28 ± 0.327
1.399CysTyr: 1.399 ± 0.558
0.0CysXaa: 0.0 ± 0.0
Asp
1.959AspAla: 1.959 ± 0.733
1.119AspCys: 1.119 ± 0.606
3.078AspAsp: 3.078 ± 0.705
1.959AspGlu: 1.959 ± 0.5
3.078AspPhe: 3.078 ± 0.253
1.959AspGly: 1.959 ± 1.032
1.119AspHis: 1.119 ± 0.422
3.358AspIle: 3.358 ± 0.382
3.358AspLys: 3.358 ± 1.095
6.715AspLeu: 6.715 ± 1.136
0.28AspMet: 0.28 ± 0.365
2.238AspAsn: 2.238 ± 0.398
1.959AspPro: 1.959 ± 0.981
2.798AspGln: 2.798 ± 0.73
1.119AspArg: 1.119 ± 0.296
5.316AspSer: 5.316 ± 0.946
3.917AspThr: 3.917 ± 0.665
1.119AspVal: 1.119 ± 0.58
0.56AspTrp: 0.56 ± 0.29
3.358AspTyr: 3.358 ± 0.47
0.0AspXaa: 0.0 ± 0.0
Glu
2.798GluAla: 2.798 ± 1.256
1.119GluCys: 1.119 ± 0.297
4.757GluAsp: 4.757 ± 0.467
3.078GluGlu: 3.078 ± 0.633
2.518GluPhe: 2.518 ± 0.131
1.959GluGly: 1.959 ± 0.668
0.839GluHis: 0.839 ± 0.383
5.596GluIle: 5.596 ± 0.398
4.477GluLys: 4.477 ± 0.67
6.435GluLeu: 6.435 ± 1.066
1.119GluMet: 1.119 ± 0.697
3.078GluAsn: 3.078 ± 0.488
0.56GluPro: 0.56 ± 0.653
2.238GluGln: 2.238 ± 0.799
1.959GluArg: 1.959 ± 0.508
3.637GluSer: 3.637 ± 0.872
3.917GluThr: 3.917 ± 0.992
4.757GluVal: 4.757 ± 1.208
0.28GluTrp: 0.28 ± 0.145
3.358GluTyr: 3.358 ± 1.143
0.28GluXaa: 0.28 ± 0.365
Phe
1.959PheAla: 1.959 ± 0.5
0.839PheCys: 0.839 ± 0.228
2.238PheAsp: 2.238 ± 0.592
2.518PheGlu: 2.518 ± 0.696
0.839PhePhe: 0.839 ± 0.556
2.238PheGly: 2.238 ± 0.398
1.119PheHis: 1.119 ± 0.58
3.637PheIle: 3.637 ± 0.759
3.637PheLys: 3.637 ± 0.696
6.435PheLeu: 6.435 ± 1.66
1.959PheMet: 1.959 ± 0.998
2.798PheAsn: 2.798 ± 1.4
1.119PhePro: 1.119 ± 0.407
2.238PheGln: 2.238 ± 0.641
1.679PheArg: 1.679 ± 0.331
5.036PheSer: 5.036 ± 0.261
3.917PheThr: 3.917 ± 1.082
1.399PheVal: 1.399 ± 0.654
0.0PheTrp: 0.0 ± 0.0
1.679PheTyr: 1.679 ± 0.312
0.0PheXaa: 0.0 ± 0.0
Gly
1.959GlyAla: 1.959 ± 0.383
0.0GlyCys: 0.0 ± 0.0
0.839GlyAsp: 0.839 ± 0.435
1.679GlyGlu: 1.679 ± 0.539
1.119GlyPhe: 1.119 ± 0.606
1.679GlyGly: 1.679 ± 0.534
0.839GlyHis: 0.839 ± 0.435
3.078GlyIle: 3.078 ± 0.247
2.238GlyLys: 2.238 ± 0.667
2.798GlyLeu: 2.798 ± 0.454
0.839GlyMet: 0.839 ± 0.315
2.518GlyAsn: 2.518 ± 0.93
1.399GlyPro: 1.399 ± 0.356
1.399GlyGln: 1.399 ± 0.447
1.119GlyArg: 1.119 ± 0.407
2.798GlySer: 2.798 ± 0.535
2.518GlyThr: 2.518 ± 0.546
2.518GlyVal: 2.518 ± 0.788
0.28GlyTrp: 0.28 ± 0.327
1.399GlyTyr: 1.399 ± 0.793
0.0GlyXaa: 0.0 ± 0.0
His
0.56HisAla: 0.56 ± 0.242
0.839HisCys: 0.839 ± 0.228
1.119HisAsp: 1.119 ± 0.274
1.119HisGlu: 1.119 ± 0.58
0.839HisPhe: 0.839 ± 0.435
0.56HisGly: 0.56 ± 0.29
1.119HisHis: 1.119 ± 0.296
3.637HisIle: 3.637 ± 0.732
2.518HisLys: 2.518 ± 0.826
2.798HisLeu: 2.798 ± 1.169
0.28HisMet: 0.28 ± 0.365
1.399HisAsn: 1.399 ± 0.268
2.518HisPro: 2.518 ± 0.691
1.399HisGln: 1.399 ± 0.268
0.839HisArg: 0.839 ± 0.435
1.399HisSer: 1.399 ± 0.617
0.839HisThr: 0.839 ± 0.724
1.119HisVal: 1.119 ± 0.802
0.56HisTrp: 0.56 ± 0.242
1.119HisTyr: 1.119 ± 0.296
0.0HisXaa: 0.0 ± 0.0
Ile
2.518IleAla: 2.518 ± 0.626
0.0IleCys: 0.0 ± 0.0
6.435IleAsp: 6.435 ± 0.869
6.715IleGlu: 6.715 ± 0.666
3.637IlePhe: 3.637 ± 0.875
2.518IleGly: 2.518 ± 0.46
2.518IleHis: 2.518 ± 0.684
6.715IleIle: 6.715 ± 0.173
8.954IleLys: 8.954 ± 1.047
7.555IleLeu: 7.555 ± 1.587
1.679IleMet: 1.679 ± 0.437
7.834IleAsn: 7.834 ± 1.995
5.316IlePro: 5.316 ± 1.218
1.959IleGln: 1.959 ± 0.508
2.798IleArg: 2.798 ± 0.474
10.073IleSer: 10.073 ± 1.527
8.394IleThr: 8.394 ± 2.029
3.078IleVal: 3.078 ± 0.247
0.56IleTrp: 0.56 ± 0.242
3.917IleTyr: 3.917 ± 0.565
0.0IleXaa: 0.0 ± 0.0
Lys
2.518LysAla: 2.518 ± 1.009
1.399LysCys: 1.399 ± 0.793
2.518LysAsp: 2.518 ± 0.826
4.757LysGlu: 4.757 ± 0.752
3.078LysPhe: 3.078 ± 0.247
1.679LysGly: 1.679 ± 0.312
1.679LysHis: 1.679 ± 0.312
7.555LysIle: 7.555 ± 1.178
3.917LysLys: 3.917 ± 1.046
8.954LysLeu: 8.954 ± 1.264
1.959LysMet: 1.959 ± 0.376
5.316LysAsn: 5.316 ± 0.754
4.197LysPro: 4.197 ± 0.585
1.959LysGln: 1.959 ± 0.384
4.197LysArg: 4.197 ± 1.27
5.316LysSer: 5.316 ± 1.243
4.757LysThr: 4.757 ± 0.608
2.238LysVal: 2.238 ± 0.844
0.28LysTrp: 0.28 ± 0.145
3.358LysTyr: 3.358 ± 0.593
0.0LysXaa: 0.0 ± 0.0
Leu
5.036LeuAla: 5.036 ± 0.602
1.679LeuCys: 1.679 ± 0.331
6.156LeuAsp: 6.156 ± 1.031
3.637LeuGlu: 3.637 ± 1.139
5.596LeuPhe: 5.596 ± 0.501
4.477LeuGly: 4.477 ± 0.501
2.518LeuHis: 2.518 ± 0.522
11.472LeuIle: 11.472 ± 1.959
6.995LeuLys: 6.995 ± 1.303
8.394LeuLeu: 8.394 ± 1.225
1.959LeuMet: 1.959 ± 0.682
4.757LeuAsn: 4.757 ± 1.916
5.316LeuPro: 5.316 ± 1.242
3.358LeuGln: 3.358 ± 0.893
5.316LeuArg: 5.316 ± 1.096
10.912LeuSer: 10.912 ± 2.271
4.197LeuThr: 4.197 ± 1.351
4.757LeuVal: 4.757 ± 1.308
1.399LeuTrp: 1.399 ± 0.511
3.917LeuTyr: 3.917 ± 0.567
0.0LeuXaa: 0.0 ± 0.0
Met
0.839MetAla: 0.839 ± 0.376
0.0MetCys: 0.0 ± 0.0
1.679MetAsp: 1.679 ± 0.631
1.399MetGlu: 1.399 ± 0.511
1.679MetPhe: 1.679 ± 0.312
0.56MetGly: 0.56 ± 0.297
0.0MetHis: 0.0 ± 0.0
1.399MetIle: 1.399 ± 0.793
1.679MetLys: 1.679 ± 0.312
1.399MetLeu: 1.399 ± 0.625
0.28MetMet: 0.28 ± 0.327
1.399MetAsn: 1.399 ± 0.526
0.28MetPro: 0.28 ± 0.145
0.839MetGln: 0.839 ± 0.336
1.119MetArg: 1.119 ± 0.407
1.119MetSer: 1.119 ± 0.336
1.679MetThr: 1.679 ± 0.824
1.119MetVal: 1.119 ± 0.708
0.56MetTrp: 0.56 ± 0.29
1.119MetTyr: 1.119 ± 0.296
0.0MetXaa: 0.0 ± 0.0
Asn
1.119AsnAla: 1.119 ± 0.336
1.399AsnCys: 1.399 ± 0.535
3.637AsnAsp: 3.637 ± 0.658
3.078AsnGlu: 3.078 ± 0.448
3.078AsnPhe: 3.078 ± 0.626
1.679AsnGly: 1.679 ± 0.423
2.238AsnHis: 2.238 ± 0.893
6.995AsnIle: 6.995 ± 1.344
3.637AsnLys: 3.637 ± 1.009
7.275AsnLeu: 7.275 ± 1.386
2.238AsnMet: 2.238 ± 0.639
3.358AsnAsn: 3.358 ± 0.382
2.518AsnPro: 2.518 ± 1.228
2.238AsnGln: 2.238 ± 0.844
2.518AsnArg: 2.518 ± 0.8
4.757AsnSer: 4.757 ± 1.036
4.197AsnThr: 4.197 ± 0.769
1.119AsnVal: 1.119 ± 0.407
0.839AsnTrp: 0.839 ± 0.723
3.078AsnTyr: 3.078 ± 0.371
0.0AsnXaa: 0.0 ± 0.0
Pro
1.119ProAla: 1.119 ± 0.336
0.839ProCys: 0.839 ± 0.348
4.197ProAsp: 4.197 ± 0.783
3.078ProGlu: 3.078 ± 0.301
1.119ProPhe: 1.119 ± 0.407
1.679ProGly: 1.679 ± 0.517
1.679ProHis: 1.679 ± 0.548
6.715ProIle: 6.715 ± 1.635
3.917ProLys: 3.917 ± 0.501
3.078ProLeu: 3.078 ± 0.448
0.56ProMet: 0.56 ± 0.29
2.798ProAsn: 2.798 ± 0.915
3.637ProPro: 3.637 ± 1.679
1.679ProGln: 1.679 ± 1.657
1.119ProArg: 1.119 ± 0.913
2.518ProSer: 2.518 ± 0.69
2.518ProThr: 2.518 ± 0.335
2.798ProVal: 2.798 ± 0.661
0.28ProTrp: 0.28 ± 0.365
1.399ProTyr: 1.399 ± 0.571
0.0ProXaa: 0.0 ± 0.0
Gln
1.119GlnAla: 1.119 ± 0.708
0.839GlnCys: 0.839 ± 0.556
1.119GlnAsp: 1.119 ± 0.274
3.917GlnGlu: 3.917 ± 0.501
0.839GlnPhe: 0.839 ± 0.336
2.238GlnGly: 2.238 ± 0.648
0.56GlnHis: 0.56 ± 0.32
2.518GlnIle: 2.518 ± 0.92
3.637GlnLys: 3.637 ± 0.536
3.917GlnLeu: 3.917 ± 1.008
0.56GlnMet: 0.56 ± 0.29
2.238GlnAsn: 2.238 ± 0.428
2.238GlnPro: 2.238 ± 1.187
1.119GlnGln: 1.119 ± 0.296
1.959GlnArg: 1.959 ± 0.844
2.798GlnSer: 2.798 ± 0.535
2.518GlnThr: 2.518 ± 0.691
1.679GlnVal: 1.679 ± 0.802
0.0GlnTrp: 0.0 ± 0.0
1.119GlnTyr: 1.119 ± 0.407
0.0GlnXaa: 0.0 ± 0.0
Arg
1.119ArgAla: 1.119 ± 0.296
0.56ArgCys: 0.56 ± 0.654
2.518ArgAsp: 2.518 ± 0.942
1.119ArgGlu: 1.119 ± 0.58
3.078ArgPhe: 3.078 ± 0.881
1.399ArgGly: 1.399 ± 0.268
1.399ArgHis: 1.399 ± 0.535
4.197ArgIle: 4.197 ± 0.769
1.959ArgLys: 1.959 ± 0.563
5.036ArgLeu: 5.036 ± 0.986
0.56ArgMet: 0.56 ± 0.73
2.518ArgAsn: 2.518 ± 1.03
1.119ArgPro: 1.119 ± 0.594
0.839ArgGln: 0.839 ± 0.336
1.399ArgArg: 1.399 ± 0.526
3.358ArgSer: 3.358 ± 0.583
3.078ArgThr: 3.078 ± 1.654
0.839ArgVal: 0.839 ± 0.724
0.839ArgTrp: 0.839 ± 0.435
2.798ArgTyr: 2.798 ± 0.471
0.0ArgXaa: 0.0 ± 0.0
Ser
3.917SerAla: 3.917 ± 1.264
2.518SerCys: 2.518 ± 0.335
3.637SerAsp: 3.637 ± 0.646
6.435SerGlu: 6.435 ± 0.973
3.917SerPhe: 3.917 ± 0.624
2.798SerGly: 2.798 ± 1.1
2.238SerHis: 2.238 ± 0.381
7.275SerIle: 7.275 ± 1.109
5.596SerLys: 5.596 ± 0.501
9.793SerLeu: 9.793 ± 1.003
1.679SerMet: 1.679 ± 0.312
4.477SerAsn: 4.477 ± 1.335
2.798SerPro: 2.798 ± 0.774
2.518SerGln: 2.518 ± 0.582
4.197SerArg: 4.197 ± 0.82
9.513SerSer: 9.513 ± 1.513
6.995SerThr: 6.995 ± 0.738
3.637SerVal: 3.637 ± 1.189
0.56SerTrp: 0.56 ± 0.654
3.917SerTyr: 3.917 ± 0.32
0.0SerXaa: 0.0 ± 0.0
Thr
1.679ThrAla: 1.679 ± 0.165
0.839ThrCys: 0.839 ± 0.336
3.078ThrAsp: 3.078 ± 0.865
3.637ThrGlu: 3.637 ± 0.373
3.078ThrPhe: 3.078 ± 1.561
1.679ThrGly: 1.679 ± 0.312
1.399ThrHis: 1.399 ± 0.558
8.114ThrIle: 8.114 ± 1.199
7.834ThrLys: 7.834 ± 1.061
6.156ThrLeu: 6.156 ± 1.266
0.839ThrMet: 0.839 ± 0.435
3.917ThrAsn: 3.917 ± 1.347
3.078ThrPro: 3.078 ± 1.215
3.358ThrGln: 3.358 ± 0.583
2.238ThrArg: 2.238 ± 0.632
5.036ThrSer: 5.036 ± 1.75
4.477ThrThr: 4.477 ± 0.846
2.798ThrVal: 2.798 ± 1.461
1.959ThrTrp: 1.959 ± 0.529
3.358ThrTyr: 3.358 ± 0.423
0.0ThrXaa: 0.0 ± 0.0
Val
0.56ValAla: 0.56 ± 0.46
1.119ValCys: 1.119 ± 0.407
1.119ValAsp: 1.119 ± 0.606
2.518ValGlu: 2.518 ± 0.793
2.798ValPhe: 2.798 ± 0.554
0.839ValGly: 0.839 ± 0.556
1.959ValHis: 1.959 ± 1.545
3.358ValIle: 3.358 ± 1.064
3.078ValLys: 3.078 ± 1.109
1.959ValLeu: 1.959 ± 0.5
1.119ValMet: 1.119 ± 0.407
2.518ValAsn: 2.518 ± 0.942
1.959ValPro: 1.959 ± 0.844
2.798ValGln: 2.798 ± 1.285
2.518ValArg: 2.518 ± 0.563
5.316ValSer: 5.316 ± 2.028
2.518ValThr: 2.518 ± 0.712
3.637ValVal: 3.637 ± 1.092
0.0ValTrp: 0.0 ± 0.0
1.679ValTyr: 1.679 ± 0.534
0.0ValXaa: 0.0 ± 0.0
Trp
0.56TrpAla: 0.56 ± 0.497
0.28TrpCys: 0.28 ± 0.145
0.0TrpAsp: 0.0 ± 0.0
1.959TrpGlu: 1.959 ± 0.932
0.56TrpPhe: 0.56 ± 0.29
0.0TrpGly: 0.0 ± 0.0
0.56TrpHis: 0.56 ± 0.32
0.56TrpIle: 0.56 ± 0.29
0.839TrpLys: 0.839 ± 0.348
0.56TrpLeu: 0.56 ± 0.29
0.0TrpMet: 0.0 ± 0.0
0.839TrpAsn: 0.839 ± 0.435
0.56TrpPro: 0.56 ± 0.32
0.0TrpGln: 0.0 ± 0.0
0.28TrpArg: 0.28 ± 0.145
0.56TrpSer: 0.56 ± 0.29
1.119TrpThr: 1.119 ± 0.296
0.56TrpVal: 0.56 ± 0.242
0.28TrpTrp: 0.28 ± 0.327
0.56TrpTyr: 0.56 ± 0.497
0.0TrpXaa: 0.0 ± 0.0
Tyr
0.839TyrAla: 0.839 ± 0.228
1.959TyrCys: 1.959 ± 0.748
1.399TyrAsp: 1.399 ± 0.447
2.518TyrGlu: 2.518 ± 0.908
2.518TyrPhe: 2.518 ± 0.789
1.119TyrGly: 1.119 ± 0.296
0.839TyrHis: 0.839 ± 0.607
3.078TyrIle: 3.078 ± 0.807
2.238TyrLys: 2.238 ± 0.524
6.435TyrLeu: 6.435 ± 1.324
1.119TyrMet: 1.119 ± 0.679
3.917TyrAsn: 3.917 ± 0.565
2.798TyrPro: 2.798 ± 0.711
1.679TyrGln: 1.679 ± 0.165
1.679TyrArg: 1.679 ± 0.165
6.156TyrSer: 6.156 ± 1.227
3.078TyrThr: 3.078 ± 0.535
0.839TyrVal: 0.839 ± 0.336
0.839TyrTrp: 0.839 ± 0.228
3.917TyrTyr: 3.917 ± 1.585
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.28XaaArg: 0.28 ± 0.365
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 4 proteins (3575 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski