Amino acid dipepetide frequency for bacteria symbiont BFo2 of Frankliniella occidentalis

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	9.235AlaAla: 9.235 ± 0.144	0.981AlaCys: 0.981 ± 0.037	4.689AlaAsp: 4.689 ± 0.081	6.004AlaGlu: 6.004 ± 0.094	3.29AlaPhe: 3.29 ± 0.067	7.175AlaGly: 7.175 ± 0.112	1.829AlaHis: 1.829 ± 0.042	6.101AlaIle: 6.101 ± 0.09	4.238AlaLys: 4.238 ± 0.094	11.388AlaLeu: 11.388 ± 0.14	2.68AlaMet: 2.68 ± 0.06	3.058AlaAsn: 3.058 ± 0.058	3.464AlaPro: 3.464 ± 0.071	4.975AlaGln: 4.975 ± 0.093	4.521AlaArg: 4.521 ± 0.076	5.669AlaSer: 5.669 ± 0.086	5.083AlaThr: 5.083 ± 0.085	6.401AlaVal: 6.401 ± 0.103	1.376AlaTrp: 1.376 ± 0.043	2.298AlaTyr: 2.298 ± 0.049	0.0AlaXaa: 0.0 ± 0.0
Cys	0.874CysAla: 0.874 ± 0.03	0.19CysCys: 0.19 ± 0.016	0.54CysAsp: 0.54 ± 0.026	0.59CysGlu: 0.59 ± 0.024	0.454CysPhe: 0.454 ± 0.023	0.925CysGly: 0.925 ± 0.036	0.358CysHis: 0.358 ± 0.021	0.515CysIle: 0.515 ± 0.024	0.29CysLys: 0.29 ± 0.018	1.08CysLeu: 1.08 ± 0.039	0.203CysMet: 0.203 ± 0.015	0.302CysAsn: 0.302 ± 0.018	0.461CysPro: 0.461 ± 0.025	0.639CysGln: 0.639 ± 0.029	0.56CysArg: 0.56 ± 0.028	0.735CysSer: 0.735 ± 0.029	0.457CysThr: 0.457 ± 0.02	0.67CysVal: 0.67 ± 0.025	0.18CysTrp: 0.18 ± 0.014	0.356CysTyr: 0.356 ± 0.02	0.0CysXaa: 0.0 ± 0.0
Asp	4.604AspAla: 4.604 ± 0.08	0.5AspCys: 0.5 ± 0.023	2.745AspAsp: 2.745 ± 0.058	3.255AspGlu: 3.255 ± 0.056	2.05AspPhe: 2.05 ± 0.048	3.252AspGly: 3.252 ± 0.078	1.273AspHis: 1.273 ± 0.045	3.461AspIle: 3.461 ± 0.061	2.488AspLys: 2.488 ± 0.059	4.77AspLeu: 4.77 ± 0.066	1.171AspMet: 1.171 ± 0.034	2.207AspAsn: 2.207 ± 0.043	2.314AspPro: 2.314 ± 0.054	2.33AspGln: 2.33 ± 0.057	2.544AspArg: 2.544 ± 0.063	2.948AspSer: 2.948 ± 0.062	2.604AspThr: 2.604 ± 0.059	3.271AspVal: 3.271 ± 0.063	0.762AspTrp: 0.762 ± 0.029	2.03AspTyr: 2.03 ± 0.049	0.0AspXaa: 0.0 ± 0.0
Glu	5.137GluAla: 5.137 ± 0.087	0.493GluCys: 0.493 ± 0.023	2.309GluAsp: 2.309 ± 0.06	3.217GluGlu: 3.217 ± 0.078	1.748GluPhe: 1.748 ± 0.041	3.621GluGly: 3.621 ± 0.069	1.454GluHis: 1.454 ± 0.046	3.417GluIle: 3.417 ± 0.067	3.139GluLys: 3.139 ± 0.064	5.646GluLeu: 5.646 ± 0.093	1.606GluMet: 1.606 ± 0.04	2.194GluAsn: 2.194 ± 0.045	1.838GluPro: 1.838 ± 0.044	3.915GluGln: 3.915 ± 0.073	3.273GluArg: 3.273 ± 0.072	3.257GluSer: 3.257 ± 0.064	2.903GluThr: 2.903 ± 0.058	3.868GluVal: 3.868 ± 0.078	0.779GluTrp: 0.779 ± 0.031	1.381GluTyr: 1.381 ± 0.041	0.001GluXaa: 0.001 ± 0.001
Phe	3.416PheAla: 3.416 ± 0.069	0.523PheCys: 0.523 ± 0.025	2.183PheAsp: 2.183 ± 0.059	1.709PheGlu: 1.709 ± 0.044	1.599PhePhe: 1.599 ± 0.05	3.058PheGly: 3.058 ± 0.059	0.808PheHis: 0.808 ± 0.03	2.652PheIle: 2.652 ± 0.068	1.322PheLys: 1.322 ± 0.04	3.21PheLeu: 3.21 ± 0.073	0.925PheMet: 0.925 ± 0.033	1.551PheAsn: 1.551 ± 0.042	1.57PhePro: 1.57 ± 0.044	1.343PheGln: 1.343 ± 0.041	1.72PheArg: 1.72 ± 0.047	3.418PheSer: 3.418 ± 0.07	2.64PheThr: 2.64 ± 0.062	2.33PheVal: 2.33 ± 0.056	0.577PheTrp: 0.577 ± 0.029	1.223PheTyr: 1.223 ± 0.039	0.0PheXaa: 0.0 ± 0.0
Gly	5.789GlyAla: 5.789 ± 0.093	0.973GlyCys: 0.973 ± 0.035	3.478GlyAsp: 3.478 ± 0.071	4.325GlyGlu: 4.325 ± 0.075	3.09GlyPhe: 3.09 ± 0.066	5.045GlyGly: 5.045 ± 0.098	1.716GlyHis: 1.716 ± 0.05	5.087GlyIle: 5.087 ± 0.081	3.947GlyLys: 3.947 ± 0.081	7.43GlyLeu: 7.43 ± 0.098	2.107GlyMet: 2.107 ± 0.057	2.777GlyAsn: 2.777 ± 0.07	2.01GlyPro: 2.01 ± 0.054	3.293GlyGln: 3.293 ± 0.072	3.693GlyArg: 3.693 ± 0.074	4.287GlySer: 4.287 ± 0.081	3.632GlyThr: 3.632 ± 0.064	5.177GlyVal: 5.177 ± 0.087	1.167GlyTrp: 1.167 ± 0.035	2.567GlyTyr: 2.567 ± 0.063	0.0GlyXaa: 0.0 ± 0.0
His	1.988HisAla: 1.988 ± 0.048	0.396HisCys: 0.396 ± 0.021	1.209HisAsp: 1.209 ± 0.04	1.018HisGlu: 1.018 ± 0.036	1.219HisPhe: 1.219 ± 0.035	1.607HisGly: 1.607 ± 0.043	0.907HisHis: 0.907 ± 0.032	1.396HisIle: 1.396 ± 0.041	0.75HisLys: 0.75 ± 0.033	2.56HisLeu: 2.56 ± 0.052	0.498HisMet: 0.498 ± 0.023	0.81HisAsn: 0.81 ± 0.033	1.481HisPro: 1.481 ± 0.041	1.561HisGln: 1.561 ± 0.044	1.377HisArg: 1.377 ± 0.039	1.56HisSer: 1.56 ± 0.043	1.144HisThr: 1.144 ± 0.035	1.233HisVal: 1.233 ± 0.036	0.502HisTrp: 0.502 ± 0.025	1.121HisTyr: 1.121 ± 0.041	0.0HisXaa: 0.0 ± 0.0
Ile	6.676IleAla: 6.676 ± 0.091	0.636IleCys: 0.636 ± 0.026	3.961IleAsp: 3.961 ± 0.074	3.598IleGlu: 3.598 ± 0.072	2.191IlePhe: 2.191 ± 0.06	4.776IleGly: 4.776 ± 0.085	1.236IleHis: 1.236 ± 0.036	3.868IleIle: 3.868 ± 0.08	2.473IleLys: 2.473 ± 0.059	5.185IleLeu: 5.185 ± 0.09	1.269IleMet: 1.269 ± 0.038	2.648IleAsn: 2.648 ± 0.056	2.774IlePro: 2.774 ± 0.059	2.082IleGln: 2.082 ± 0.044	3.016IleArg: 3.016 ± 0.062	4.203IleSer: 4.203 ± 0.074	4.034IleThr: 4.034 ± 0.072	3.885IleVal: 3.885 ± 0.063	0.661IleTrp: 0.661 ± 0.032	1.446IleTyr: 1.446 ± 0.04	0.001IleXaa: 0.001 ± 0.001
Lys	4.163LysAla: 4.163 ± 0.089	0.229LysCys: 0.229 ± 0.016	1.958LysAsp: 1.958 ± 0.054	2.371LysGlu: 2.371 ± 0.062	1.139LysPhe: 1.139 ± 0.037	2.96LysGly: 2.96 ± 0.068	0.974LysHis: 0.974 ± 0.036	2.635LysIle: 2.635 ± 0.059	2.312LysLys: 2.312 ± 0.064	4.207LysLeu: 4.207 ± 0.063	1.227LysMet: 1.227 ± 0.038	1.677LysAsn: 1.677 ± 0.04	1.961LysPro: 1.961 ± 0.052	2.429LysGln: 2.429 ± 0.052	2.442LysArg: 2.442 ± 0.054	2.482LysSer: 2.482 ± 0.058	2.543LysThr: 2.543 ± 0.051	3.043LysVal: 3.043 ± 0.063	0.47LysTrp: 0.47 ± 0.029	1.052LysTyr: 1.052 ± 0.034	0.0LysXaa: 0.0 ± 0.0
Leu	11.317LeuAla: 11.317 ± 0.134	1.268LeuCys: 1.268 ± 0.048	5.229LeuAsp: 5.229 ± 0.08	5.105LeuGlu: 5.105 ± 0.095	4.315LeuPhe: 4.315 ± 0.093	7.294LeuGly: 7.294 ± 0.114	2.375LeuHis: 2.375 ± 0.058	6.214LeuIle: 6.214 ± 0.108	4.317LeuLys: 4.317 ± 0.068	11.883LeuLeu: 11.883 ± 0.171	2.608LeuMet: 2.608 ± 0.058	4.11LeuAsn: 4.11 ± 0.073	5.618LeuPro: 5.618 ± 0.089	4.74LeuGln: 4.74 ± 0.083	5.777LeuArg: 5.777 ± 0.087	8.336LeuSer: 8.336 ± 0.118	7.216LeuThr: 7.216 ± 0.09	7.009LeuVal: 7.009 ± 0.1	1.359LeuTrp: 1.359 ± 0.048	2.68LeuTyr: 2.68 ± 0.056	0.005LeuXaa: 0.005 ± 0.003
Met	2.542MetAla: 2.542 ± 0.057	0.162MetCys: 0.162 ± 0.013	1.05MetAsp: 1.05 ± 0.036	1.044MetGlu: 1.044 ± 0.037	0.81MetPhe: 0.81 ± 0.027	1.696MetGly: 1.696 ± 0.05	0.488MetHis: 0.488 ± 0.024	1.481MetIle: 1.481 ± 0.039	1.248MetLys: 1.248 ± 0.037	2.688MetLeu: 2.688 ± 0.064	0.798MetMet: 0.798 ± 0.036	0.962MetAsn: 0.962 ± 0.033	1.187MetPro: 1.187 ± 0.037	1.198MetGln: 1.198 ± 0.041	1.281MetArg: 1.281 ± 0.037	1.88MetSer: 1.88 ± 0.044	1.78MetThr: 1.78 ± 0.051	1.801MetVal: 1.801 ± 0.05	0.216MetTrp: 0.216 ± 0.014	0.423MetTyr: 0.423 ± 0.02	0.001MetXaa: 0.001 ± 0.001
Asn	3.299AsnAla: 3.299 ± 0.064	0.314AsnCys: 0.314 ± 0.019	2.041AsnAsp: 2.041 ± 0.044	1.807AsnGlu: 1.807 ± 0.054	1.308AsnPhe: 1.308 ± 0.038	2.67AsnGly: 2.67 ± 0.068	0.911AsnHis: 0.911 ± 0.033	2.287AsnIle: 2.287 ± 0.048	1.535AsnLys: 1.535 ± 0.045	3.405AsnLeu: 3.405 ± 0.062	0.768AsnMet: 0.768 ± 0.028	1.555AsnAsn: 1.555 ± 0.046	1.984AsnPro: 1.984 ± 0.051	1.944AsnGln: 1.944 ± 0.055	1.927AsnArg: 1.927 ± 0.048	2.236AsnSer: 2.236 ± 0.053	2.149AsnThr: 2.149 ± 0.057	2.413AsnVal: 2.413 ± 0.051	0.532AsnTrp: 0.532 ± 0.028	1.147AsnTyr: 1.147 ± 0.039	0.0AsnXaa: 0.0 ± 0.0
Pro	4.164ProAla: 4.164 ± 0.083	0.378ProCys: 0.378 ± 0.019	2.426ProAsp: 2.426 ± 0.053	3.225ProGlu: 3.225 ± 0.063	1.778ProPhe: 1.778 ± 0.053	2.863ProGly: 2.863 ± 0.063	1.178ProHis: 1.178 ± 0.037	2.404ProIle: 2.404 ± 0.047	1.611ProLys: 1.611 ± 0.043	5.172ProLeu: 5.172 ± 0.094	1.056ProMet: 1.056 ± 0.032	1.432ProAsn: 1.432 ± 0.038	1.55ProPro: 1.55 ± 0.045	2.328ProGln: 2.328 ± 0.056	1.847ProArg: 1.847 ± 0.053	2.752ProSer: 2.752 ± 0.06	2.478ProThr: 2.478 ± 0.057	3.385ProVal: 3.385 ± 0.075	0.708ProTrp: 0.708 ± 0.027	1.273ProTyr: 1.273 ± 0.041	0.001ProXaa: 0.001 ± 0.001
Gln	5.481GlnAla: 5.481 ± 0.086	0.473GlnCys: 0.473 ± 0.026	2.037GlnAsp: 2.037 ± 0.055	2.31GlnGlu: 2.31 ± 0.054	1.788GlnPhe: 1.788 ± 0.043	4.006GlnGly: 4.006 ± 0.074	1.667GlnHis: 1.667 ± 0.048	2.511GlnIle: 2.511 ± 0.054	1.924GlnLys: 1.924 ± 0.047	6.549GlnLeu: 6.549 ± 0.11	1.114GlnMet: 1.114 ± 0.038	1.43GlnAsn: 1.43 ± 0.049	2.495GlnPro: 2.495 ± 0.071	5.231GlnGln: 5.231 ± 0.162	3.594GlnArg: 3.594 ± 0.073	2.954GlnSer: 2.954 ± 0.063	2.435GlnThr: 2.435 ± 0.061	3.484GlnVal: 3.484 ± 0.077	0.899GlnTrp: 0.899 ± 0.034	1.338GlnTyr: 1.338 ± 0.038	0.0GlnXaa: 0.0 ± 0.0
Arg	4.112ArgAla: 4.112 ± 0.065	0.547ArgCys: 0.547 ± 0.024	2.76ArgAsp: 2.76 ± 0.062	3.443ArgGlu: 3.443 ± 0.073	2.406ArgPhe: 2.406 ± 0.056	3.2ArgGly: 3.2 ± 0.062	1.579ArgHis: 1.579 ± 0.042	3.117ArgIle: 3.117 ± 0.063	2.292ArgLys: 2.292 ± 0.054	6.158ArgLeu: 6.158 ± 0.11	1.257ArgMet: 1.257 ± 0.036	1.758ArgAsn: 1.758 ± 0.043	2.127ArgPro: 2.127 ± 0.049	3.452ArgGln: 3.452 ± 0.074	3.182ArgArg: 3.182 ± 0.075	2.893ArgSer: 2.893 ± 0.055	2.334ArgThr: 2.334 ± 0.047	3.454ArgVal: 3.454 ± 0.064	0.863ArgTrp: 0.863 ± 0.033	2.164ArgTyr: 2.164 ± 0.051	0.0ArgXaa: 0.0 ± 0.0
Ser	6.182SerAla: 6.182 ± 0.091	0.573SerCys: 0.573 ± 0.029	3.308SerAsp: 3.308 ± 0.067	3.5SerGlu: 3.5 ± 0.07	2.4SerPhe: 2.4 ± 0.053	5.254SerGly: 5.254 ± 0.074	1.747SerHis: 1.747 ± 0.049	3.526SerIle: 3.526 ± 0.07	2.182SerLys: 2.182 ± 0.045	7.626SerLeu: 7.626 ± 0.089	1.502SerMet: 1.502 ± 0.043	1.936SerAsn: 1.936 ± 0.051	2.931SerPro: 2.931 ± 0.057	3.492SerGln: 3.492 ± 0.063	3.445SerArg: 3.445 ± 0.062	4.189SerSer: 4.189 ± 0.086	3.539SerThr: 3.539 ± 0.064	4.479SerVal: 4.479 ± 0.075	1.001SerTrp: 1.001 ± 0.034	1.721SerTyr: 1.721 ± 0.047	0.002SerXaa: 0.002 ± 0.002
Thr	5.471ThrAla: 5.471 ± 0.096	0.454ThrCys: 0.454 ± 0.024	2.874ThrAsp: 2.874 ± 0.059	2.926ThrGlu: 2.926 ± 0.06	2.121ThrPhe: 2.121 ± 0.05	4.46ThrGly: 4.46 ± 0.07	1.407ThrHis: 1.407 ± 0.038	2.991ThrIle: 2.991 ± 0.062	1.746ThrLys: 1.746 ± 0.046	7.825ThrLeu: 7.825 ± 0.111	1.071ThrMet: 1.071 ± 0.034	1.658ThrAsn: 1.658 ± 0.045	3.445ThrPro: 3.445 ± 0.072	2.919ThrGln: 2.919 ± 0.062	2.828ThrArg: 2.828 ± 0.048	3.256ThrSer: 3.256 ± 0.067	3.333ThrThr: 3.333 ± 0.072	4.087ThrVal: 4.087 ± 0.091	0.772ThrTrp: 0.772 ± 0.029	1.322ThrTyr: 1.322 ± 0.039	0.0ThrXaa: 0.0 ± 0.0
Val	6.636ValAla: 6.636 ± 0.097	0.682ValCys: 0.682 ± 0.032	3.648ValAsp: 3.648 ± 0.074	4.095ValGlu: 4.095 ± 0.069	2.287ValPhe: 2.287 ± 0.053	4.742ValGly: 4.742 ± 0.085	1.128ValHis: 1.128 ± 0.038	4.871ValIle: 4.871 ± 0.085	3.101ValLys: 3.101 ± 0.066	6.63ValLeu: 6.63 ± 0.102	1.984ValMet: 1.984 ± 0.056	2.796ValAsn: 2.796 ± 0.063	2.73ValPro: 2.73 ± 0.061	2.334ValGln: 2.334 ± 0.052	3.169ValArg: 3.169 ± 0.068	4.721ValSer: 4.721 ± 0.073	4.607ValThr: 4.607 ± 0.083	5.301ValVal: 5.301 ± 0.086	0.847ValTrp: 0.847 ± 0.032	1.61ValTyr: 1.61 ± 0.043	0.0ValXaa: 0.0 ± 0.0
Trp	0.919TrpAla: 0.919 ± 0.029	0.198TrpCys: 0.198 ± 0.015	0.585TrpAsp: 0.585 ± 0.028	0.507TrpGlu: 0.507 ± 0.023	0.626TrpPhe: 0.626 ± 0.029	0.894TrpGly: 0.894 ± 0.033	0.446TrpHis: 0.446 ± 0.021	0.776TrpIle: 0.776 ± 0.033	0.496TrpLys: 0.496 ± 0.023	2.094TrpLeu: 2.094 ± 0.057	0.367TrpMet: 0.367 ± 0.021	0.446TrpAsn: 0.446 ± 0.02	0.627TrpPro: 0.627 ± 0.03	1.378TrpGln: 1.378 ± 0.044	0.925TrpArg: 0.925 ± 0.036	0.861TrpSer: 0.861 ± 0.033	0.579TrpThr: 0.579 ± 0.026	1.004TrpVal: 1.004 ± 0.037	0.214TrpTrp: 0.214 ± 0.017	0.389TrpTyr: 0.389 ± 0.022	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.447TyrAla: 2.447 ± 0.05	0.41TyrCys: 0.41 ± 0.022	1.55TyrAsp: 1.55 ± 0.041	1.146TyrGlu: 1.146 ± 0.038	1.159TyrPhe: 1.159 ± 0.034	2.092TyrGly: 2.092 ± 0.054	0.855TyrHis: 0.855 ± 0.029	1.31TyrIle: 1.31 ± 0.038	0.864TyrLys: 0.864 ± 0.031	3.263TyrLeu: 3.263 ± 0.072	0.523TyrMet: 0.523 ± 0.026	0.923TyrAsn: 0.923 ± 0.035	1.444TyrPro: 1.444 ± 0.051	2.138TyrGln: 2.138 ± 0.049	1.976TyrArg: 1.976 ± 0.045	1.898TyrSer: 1.898 ± 0.049	1.476TyrThr: 1.476 ± 0.043	1.622TyrVal: 1.622 ± 0.045	0.446TyrTrp: 0.446 ± 0.026	0.921TyrTyr: 0.921 ± 0.041	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.001XaaGlu: 0.001 ± 0.001	0.0XaaPhe: 0.0 ± 0.0	0.001XaaGly: 0.001 ± 0.001	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.003XaaLeu: 0.003 ± 0.002	0.0XaaMet: 0.0 ± 0.0	0.001XaaAsn: 0.001 ± 0.001	0.0XaaPro: 0.0 ± 0.0	0.001XaaGln: 0.001 ± 0.001	0.001XaaArg: 0.001 ± 0.001	0.001XaaSer: 0.001 ± 0.001	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.001XaaTrp: 0.001 ± 0.001	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 2909 proteins (883206 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

---