Amino acid dipepetide frequency for Hubei qinvirus-like virus 1

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
10.959AlaAla: 10.959 ± 3.772
2.74AlaCys: 2.74 ± 1.27
5.479AlaAsp: 5.479 ± 1.232
5.936AlaGlu: 5.936 ± 2.316
2.74AlaPhe: 2.74 ± 1.27
7.763AlaGly: 7.763 ± 2.727
2.283AlaHis: 2.283 ± 1.121
3.196AlaIle: 3.196 ± 1.569
3.653AlaLys: 3.653 ± 0.486
10.959AlaLeu: 10.959 ± 0.15
3.653AlaMet: 3.653 ± 1.794
1.826AlaAsn: 1.826 ± 0.897
4.11AlaPro: 4.11 ± 0.597
4.11AlaGln: 4.11 ± 0.71
5.936AlaArg: 5.936 ± 3.623
6.849AlaSer: 6.849 ± 2.055
6.849AlaThr: 6.849 ± 3.175
6.849AlaVal: 6.849 ± 0.56
1.826AlaTrp: 1.826 ± 0.411
3.196AlaTyr: 3.196 ± 1.046
0.0AlaXaa: 0.0 ± 0.0
Cys
1.37CysAla: 1.37 ± 1.943
0.0CysCys: 0.0 ± 0.0
0.913CysAsp: 0.913 ± 0.448
0.457CysGlu: 0.457 ± 0.224
0.457CysPhe: 0.457 ± 0.224
1.826CysGly: 1.826 ± 0.411
0.457CysHis: 0.457 ± 0.224
0.457CysIle: 0.457 ± 0.224
1.37CysLys: 1.37 ± 0.673
2.74CysLeu: 2.74 ± 0.038
0.0CysMet: 0.0 ± 0.0
1.37CysAsn: 1.37 ± 0.673
0.457CysPro: 0.457 ± 0.224
0.0CysGln: 0.0 ± 0.0
1.826CysArg: 1.826 ± 0.411
0.457CysSer: 0.457 ± 0.224
1.826CysThr: 1.826 ± 0.897
1.826CysVal: 1.826 ± 0.897
0.913CysTrp: 0.913 ± 0.448
0.913CysTyr: 0.913 ± 0.448
0.0CysXaa: 0.0 ± 0.0
Asp
5.023AspAla: 5.023 ± 0.149
1.37AspCys: 1.37 ± 0.635
5.023AspAsp: 5.023 ± 1.159
5.479AspGlu: 5.479 ± 2.69
2.283AspPhe: 2.283 ± 0.187
3.196AspGly: 3.196 ± 1.046
1.37AspHis: 1.37 ± 0.673
2.283AspIle: 2.283 ± 0.187
0.457AspLys: 0.457 ± 0.224
5.936AspLeu: 5.936 ± 0.299
1.826AspMet: 1.826 ± 0.411
0.457AspAsn: 0.457 ± 0.224
2.74AspPro: 2.74 ± 1.27
1.37AspGln: 1.37 ± 0.673
4.11AspArg: 4.11 ± 2.018
2.74AspSer: 2.74 ± 1.27
3.196AspThr: 3.196 ± 1.046
4.566AspVal: 4.566 ± 0.934
0.457AspTrp: 0.457 ± 1.083
1.826AspTyr: 1.826 ± 0.411
0.0AspXaa: 0.0 ± 0.0
Glu
5.936GluAla: 5.936 ± 1.607
0.0GluCys: 0.0 ± 0.0
4.566GluAsp: 4.566 ± 0.373
5.023GluGlu: 5.023 ± 2.466
1.37GluPhe: 1.37 ± 0.673
6.849GluGly: 6.849 ± 0.748
0.913GluHis: 0.913 ± 0.448
2.74GluIle: 2.74 ± 1.345
3.196GluLys: 3.196 ± 0.262
4.11GluLeu: 4.11 ± 0.597
0.913GluMet: 0.913 ± 0.448
3.196GluAsn: 3.196 ± 0.262
1.826GluPro: 1.826 ± 1.718
2.74GluGln: 2.74 ± 1.27
3.196GluArg: 3.196 ± 0.262
2.74GluSer: 2.74 ± 1.345
5.023GluThr: 5.023 ± 2.466
6.849GluVal: 6.849 ± 0.748
0.913GluTrp: 0.913 ± 0.448
3.196GluTyr: 3.196 ± 1.569
0.0GluXaa: 0.0 ± 0.0
Phe
1.826PheAla: 1.826 ± 0.411
0.913PheCys: 0.913 ± 0.448
2.74PheAsp: 2.74 ± 1.345
3.196PheGlu: 3.196 ± 2.353
0.0PhePhe: 0.0 ± 0.0
0.913PheGly: 0.913 ± 0.448
0.0PheHis: 0.0 ± 0.0
0.0PheIle: 0.0 ± 0.0
1.826PheLys: 1.826 ± 0.411
2.74PheLeu: 2.74 ± 0.038
1.826PheMet: 1.826 ± 0.897
2.283PheAsn: 2.283 ± 1.121
1.37PhePro: 1.37 ± 0.635
1.826PheGln: 1.826 ± 0.411
2.74PheArg: 2.74 ± 1.345
1.826PheSer: 1.826 ± 0.411
0.0PheThr: 0.0 ± 0.0
1.826PheVal: 1.826 ± 0.411
0.457PheTrp: 0.457 ± 0.224
0.0PheTyr: 0.0 ± 0.0
0.0PheXaa: 0.0 ± 0.0
Gly
8.219GlyAla: 8.219 ± 1.42
1.37GlyCys: 1.37 ± 0.673
4.566GlyAsp: 4.566 ± 0.373
1.826GlyGlu: 1.826 ± 1.718
2.74GlyPhe: 2.74 ± 1.345
4.11GlyGly: 4.11 ± 2.018
1.37GlyHis: 1.37 ± 1.943
6.393GlyIle: 6.393 ± 1.831
4.566GlyLys: 4.566 ± 1.681
7.306GlyLeu: 7.306 ± 2.28
1.826GlyMet: 1.826 ± 0.897
2.74GlyAsn: 2.74 ± 0.038
0.913GlyPro: 0.913 ± 0.859
2.283GlyGln: 2.283 ± 1.494
5.023GlyArg: 5.023 ± 4.072
5.023GlySer: 5.023 ± 2.764
4.566GlyThr: 4.566 ± 0.934
3.653GlyVal: 3.653 ± 0.822
2.283GlyTrp: 2.283 ± 1.121
2.74GlyTyr: 2.74 ± 1.27
0.0GlyXaa: 0.0 ± 0.0
His
2.74HisAla: 2.74 ± 0.038
0.913HisCys: 0.913 ± 0.448
1.37HisAsp: 1.37 ± 0.673
1.37HisGlu: 1.37 ± 0.673
1.37HisPhe: 1.37 ± 0.635
4.11HisGly: 4.11 ± 2.018
1.826HisHis: 1.826 ± 1.718
0.457HisIle: 0.457 ± 1.083
0.457HisLys: 0.457 ± 0.224
1.826HisLeu: 1.826 ± 0.411
0.457HisMet: 0.457 ± 0.224
0.457HisAsn: 0.457 ± 0.224
0.0HisPro: 0.0 ± 0.0
0.457HisGln: 0.457 ± 0.224
2.74HisArg: 2.74 ± 0.038
1.826HisSer: 1.826 ± 0.897
1.826HisThr: 1.826 ± 1.718
2.283HisVal: 2.283 ± 1.121
0.457HisTrp: 0.457 ± 1.083
0.0HisTyr: 0.0 ± 0.0
0.0HisXaa: 0.0 ± 0.0
Ile
5.479IleAla: 5.479 ± 2.54
0.457IleCys: 0.457 ± 0.224
0.913IleAsp: 0.913 ± 0.448
1.826IleGlu: 1.826 ± 0.411
1.826IlePhe: 1.826 ± 0.897
1.826IleGly: 1.826 ± 0.411
1.37IleHis: 1.37 ± 0.673
3.653IleIle: 3.653 ± 0.486
1.37IleLys: 1.37 ± 0.673
3.653IleLeu: 3.653 ± 0.486
1.37IleMet: 1.37 ± 0.673
1.826IleAsn: 1.826 ± 0.897
3.196IlePro: 3.196 ± 1.046
3.653IleGln: 3.653 ± 0.822
2.74IleArg: 2.74 ± 0.038
3.196IleSer: 3.196 ± 0.262
3.196IleThr: 3.196 ± 0.262
1.37IleVal: 1.37 ± 0.635
0.913IleTrp: 0.913 ± 0.448
1.826IleTyr: 1.826 ± 0.897
0.0IleXaa: 0.0 ± 0.0
Lys
2.74LysAla: 2.74 ± 1.345
0.913LysCys: 0.913 ± 0.448
1.37LysAsp: 1.37 ± 0.635
3.196LysGlu: 3.196 ± 1.569
0.457LysPhe: 0.457 ± 1.083
2.74LysGly: 2.74 ± 1.345
1.826LysHis: 1.826 ± 0.897
1.826LysIle: 1.826 ± 0.411
3.196LysLys: 3.196 ± 1.569
3.196LysLeu: 3.196 ± 1.046
1.37LysMet: 1.37 ± 0.673
0.913LysAsn: 0.913 ± 0.859
2.283LysPro: 2.283 ± 1.121
0.913LysGln: 0.913 ± 0.859
2.74LysArg: 2.74 ± 1.345
4.11LysSer: 4.11 ± 0.597
3.196LysThr: 3.196 ± 1.569
5.479LysVal: 5.479 ± 1.232
0.0LysTrp: 0.0 ± 0.0
1.826LysTyr: 1.826 ± 0.897
0.0LysXaa: 0.0 ± 0.0
Leu
10.502LeuAla: 10.502 ± 2.541
1.826LeuCys: 1.826 ± 0.897
4.11LeuAsp: 4.11 ± 2.018
5.936LeuGlu: 5.936 ± 2.915
3.196LeuPhe: 3.196 ± 1.569
10.046LeuGly: 10.046 ± 1.606
1.37LeuHis: 1.37 ± 0.673
1.826LeuIle: 1.826 ± 0.897
2.74LeuLys: 2.74 ± 1.345
5.023LeuLeu: 5.023 ± 0.149
3.196LeuMet: 3.196 ± 0.406
4.11LeuAsn: 4.11 ± 0.597
5.936LeuPro: 5.936 ± 0.299
1.37LeuGln: 1.37 ± 1.943
4.11LeuArg: 4.11 ± 3.213
8.219LeuSer: 8.219 ± 1.195
6.849LeuThr: 6.849 ± 0.748
4.566LeuVal: 4.566 ± 1.681
0.457LeuTrp: 0.457 ± 0.224
3.196LeuTyr: 3.196 ± 1.569
0.0LeuXaa: 0.0 ± 0.0
Met
3.653MetAla: 3.653 ± 0.822
0.457MetCys: 0.457 ± 0.224
0.913MetAsp: 0.913 ± 0.448
2.74MetGlu: 2.74 ± 1.345
1.826MetPhe: 1.826 ± 0.897
0.913MetGly: 0.913 ± 0.448
0.0MetHis: 0.0 ± 0.0
0.913MetIle: 0.913 ± 0.448
1.37MetLys: 1.37 ± 0.673
1.37MetLeu: 1.37 ± 0.635
1.826MetMet: 1.826 ± 0.897
0.913MetAsn: 0.913 ± 0.448
1.37MetPro: 1.37 ± 0.635
1.37MetGln: 1.37 ± 0.673
3.196MetArg: 3.196 ± 1.569
1.826MetSer: 1.826 ± 0.897
2.283MetThr: 2.283 ± 1.494
1.37MetVal: 1.37 ± 0.635
0.457MetTrp: 0.457 ± 0.224
1.37MetTyr: 1.37 ± 0.673
0.0MetXaa: 0.0 ± 0.0
Asn
3.196AsnAla: 3.196 ± 1.569
0.457AsnCys: 0.457 ± 0.224
1.37AsnAsp: 1.37 ± 0.673
4.11AsnGlu: 4.11 ± 1.905
1.37AsnPhe: 1.37 ± 0.635
1.37AsnGly: 1.37 ± 0.635
1.37AsnHis: 1.37 ± 0.635
2.283AsnIle: 2.283 ± 1.494
0.0AsnLys: 0.0 ± 0.0
4.566AsnLeu: 4.566 ± 2.242
2.74AsnMet: 2.74 ± 0.745
1.826AsnAsn: 1.826 ± 0.897
1.826AsnPro: 1.826 ± 1.718
0.457AsnGln: 0.457 ± 0.224
1.37AsnArg: 1.37 ± 0.673
2.74AsnSer: 2.74 ± 0.038
2.283AsnThr: 2.283 ± 1.121
2.283AsnVal: 2.283 ± 1.494
0.913AsnTrp: 0.913 ± 0.448
1.826AsnTyr: 1.826 ± 0.897
0.0AsnXaa: 0.0 ± 0.0
Pro
2.74ProAla: 2.74 ± 3.885
0.0ProCys: 0.0 ± 0.0
3.196ProAsp: 3.196 ± 0.262
2.283ProGlu: 2.283 ± 1.121
0.457ProPhe: 0.457 ± 1.083
3.653ProGly: 3.653 ± 0.822
0.913ProHis: 0.913 ± 0.859
1.826ProIle: 1.826 ± 0.411
2.74ProLys: 2.74 ± 0.038
4.566ProLeu: 4.566 ± 0.934
1.37ProMet: 1.37 ± 0.673
2.74ProAsn: 2.74 ± 2.578
1.826ProPro: 1.826 ± 1.718
0.457ProGln: 0.457 ± 0.224
4.11ProArg: 4.11 ± 2.018
2.283ProSer: 2.283 ± 1.121
0.457ProThr: 0.457 ± 1.083
1.37ProVal: 1.37 ± 0.673
0.457ProTrp: 0.457 ± 0.224
0.913ProTyr: 0.913 ± 0.859
0.0ProXaa: 0.0 ± 0.0
Gln
2.283GlnAla: 2.283 ± 0.187
1.37GlnCys: 1.37 ± 0.635
0.457GlnAsp: 0.457 ± 0.224
1.37GlnGlu: 1.37 ± 0.673
0.457GlnPhe: 0.457 ± 1.083
3.653GlnGly: 3.653 ± 3.437
0.457GlnHis: 0.457 ± 0.224
2.283GlnIle: 2.283 ± 1.494
0.913GlnLys: 0.913 ± 0.448
1.826GlnLeu: 1.826 ± 0.411
0.913GlnMet: 0.913 ± 0.859
1.37GlnAsn: 1.37 ± 0.673
0.913GlnPro: 0.913 ± 0.448
0.457GlnGln: 0.457 ± 1.083
1.826GlnArg: 1.826 ± 0.411
2.283GlnSer: 2.283 ± 1.494
3.196GlnThr: 3.196 ± 1.046
1.826GlnVal: 1.826 ± 0.897
1.37GlnTrp: 1.37 ± 0.635
0.0GlnTyr: 0.0 ± 0.0
0.0GlnXaa: 0.0 ± 0.0
Arg
10.502ArgAla: 10.502 ± 0.074
1.826ArgCys: 1.826 ± 0.897
3.653ArgAsp: 3.653 ± 0.486
7.306ArgGlu: 7.306 ± 2.28
2.74ArgPhe: 2.74 ± 0.038
5.023ArgGly: 5.023 ± 2.466
2.283ArgHis: 2.283 ± 0.187
2.74ArgIle: 2.74 ± 1.27
4.566ArgLys: 4.566 ± 0.934
2.74ArgLeu: 2.74 ± 1.27
1.826ArgMet: 1.826 ± 0.411
1.37ArgAsn: 1.37 ± 0.635
0.913ArgPro: 0.913 ± 0.448
1.37ArgGln: 1.37 ± 0.635
1.826ArgArg: 1.826 ± 0.897
4.11ArgSer: 4.11 ± 1.905
1.37ArgThr: 1.37 ± 0.673
7.306ArgVal: 7.306 ± 0.336
0.913ArgTrp: 0.913 ± 0.448
3.196ArgTyr: 3.196 ± 1.046
0.0ArgXaa: 0.0 ± 0.0
Ser
5.479SerAla: 5.479 ± 6.463
1.826SerCys: 1.826 ± 0.897
5.936SerAsp: 5.936 ± 6.239
4.566SerGlu: 4.566 ± 0.934
2.283SerPhe: 2.283 ± 0.187
3.196SerGly: 3.196 ± 1.569
1.826SerHis: 1.826 ± 0.897
3.653SerIle: 3.653 ± 1.794
1.37SerLys: 1.37 ± 0.673
7.306SerLeu: 7.306 ± 2.28
2.283SerMet: 2.283 ± 0.187
3.196SerAsn: 3.196 ± 1.046
3.196SerPro: 3.196 ± 0.262
0.913SerGln: 0.913 ± 0.448
5.936SerArg: 5.936 ± 2.915
6.849SerSer: 6.849 ± 0.748
3.653SerThr: 3.653 ± 2.129
2.74SerVal: 2.74 ± 1.345
0.457SerTrp: 0.457 ± 0.224
4.566SerTyr: 4.566 ± 0.934
0.0SerXaa: 0.0 ± 0.0
Thr
6.849ThrAla: 6.849 ± 0.56
1.37ThrCys: 1.37 ± 0.635
1.826ThrAsp: 1.826 ± 0.897
1.37ThrGlu: 1.37 ± 0.673
1.37ThrPhe: 1.37 ± 0.673
4.566ThrGly: 4.566 ± 0.373
2.283ThrHis: 2.283 ± 0.187
2.283ThrIle: 2.283 ± 0.187
2.74ThrLys: 2.74 ± 1.27
5.479ThrLeu: 5.479 ± 1.383
0.0ThrMet: 0.0 ± 0.0
4.566ThrAsn: 4.566 ± 1.681
3.196ThrPro: 3.196 ± 1.569
0.913ThrGln: 0.913 ± 0.859
4.11ThrArg: 4.11 ± 0.597
5.023ThrSer: 5.023 ± 1.159
3.196ThrThr: 3.196 ± 0.262
4.11ThrVal: 4.11 ± 1.905
1.37ThrTrp: 1.37 ± 0.635
0.913ThrTyr: 0.913 ± 0.448
0.0ThrXaa: 0.0 ± 0.0
Val
5.479ValAla: 5.479 ± 1.232
1.37ValCys: 1.37 ± 0.673
5.479ValAsp: 5.479 ± 0.075
4.11ValGlu: 4.11 ± 0.71
0.913ValPhe: 0.913 ± 0.448
5.023ValGly: 5.023 ± 5.379
3.196ValHis: 3.196 ± 0.262
2.74ValIle: 2.74 ± 1.27
5.023ValLys: 5.023 ± 0.149
8.219ValLeu: 8.219 ± 0.113
1.37ValMet: 1.37 ± 0.673
1.37ValAsn: 1.37 ± 0.635
1.826ValPro: 1.826 ± 0.897
4.11ValGln: 4.11 ± 3.213
4.566ValArg: 4.566 ± 1.681
4.11ValSer: 4.11 ± 0.71
2.283ValThr: 2.283 ± 1.121
2.74ValVal: 2.74 ± 1.27
0.457ValTrp: 0.457 ± 0.224
2.283ValTyr: 2.283 ± 1.121
0.0ValXaa: 0.0 ± 0.0
Trp
1.826TrpAla: 1.826 ± 0.411
0.0TrpCys: 0.0 ± 0.0
0.457TrpAsp: 0.457 ± 0.224
1.37TrpGlu: 1.37 ± 0.673
0.457TrpPhe: 0.457 ± 0.224
0.913TrpGly: 0.913 ± 0.448
0.913TrpHis: 0.913 ± 0.859
0.457TrpIle: 0.457 ± 0.224
1.37TrpLys: 1.37 ± 0.673
0.913TrpLeu: 0.913 ± 0.448
0.457TrpMet: 0.457 ± 0.224
0.913TrpAsn: 0.913 ± 0.448
0.0TrpPro: 0.0 ± 0.0
0.457TrpGln: 0.457 ± 0.224
0.913TrpArg: 0.913 ± 0.448
2.283TrpSer: 2.283 ± 0.187
0.913TrpThr: 0.913 ± 0.859
0.913TrpVal: 0.913 ± 0.859
0.457TrpTrp: 0.457 ± 1.083
0.457TrpTyr: 0.457 ± 0.224
0.0TrpXaa: 0.0 ± 0.0
Tyr
4.11TyrAla: 4.11 ± 0.71
0.457TyrCys: 0.457 ± 0.224
1.37TyrAsp: 1.37 ± 0.673
1.826TyrGlu: 1.826 ± 0.897
0.0TyrPhe: 0.0 ± 0.0
1.826TyrGly: 1.826 ± 0.897
0.913TyrHis: 0.913 ± 0.448
3.653TyrIle: 3.653 ± 0.486
1.37TyrLys: 1.37 ± 0.673
4.566TyrLeu: 4.566 ± 0.373
0.457TyrMet: 0.457 ± 0.224
0.913TyrAsn: 0.913 ± 0.448
0.457TyrPro: 0.457 ± 1.083
0.0TyrGln: 0.0 ± 0.0
4.566TyrArg: 4.566 ± 2.242
2.74TyrSer: 2.74 ± 0.038
1.37TyrThr: 1.37 ± 0.673
2.74TyrVal: 2.74 ± 2.578
0.913TyrTrp: 0.913 ± 0.448
1.37TyrTyr: 1.37 ± 0.673
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 2 proteins (2191 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski