Amino acid dipepetide frequency for Beihai sobemo-like virus 19

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
6.335AlaAla: 6.335 ± 1.423
0.905AlaCys: 0.905 ± 0.443
2.715AlaAsp: 2.715 ± 1.33
3.62AlaGlu: 3.62 ± 1.774
4.525AlaPhe: 4.525 ± 0.536
7.24AlaGly: 7.24 ± 1.495
2.715AlaHis: 2.715 ± 0.351
6.335AlaIle: 6.335 ± 0.258
2.715AlaLys: 2.715 ± 1.33
1.81AlaLeu: 1.81 ± 0.794
3.62AlaMet: 3.62 ± 0.093
0.905AlaAsn: 0.905 ± 0.443
1.81AlaPro: 1.81 ± 0.887
3.62AlaGln: 3.62 ± 0.093
1.81AlaArg: 1.81 ± 0.887
7.24AlaSer: 7.24 ± 3.547
0.905AlaThr: 0.905 ± 0.443
2.715AlaVal: 2.715 ± 0.351
0.905AlaTrp: 0.905 ± 0.443
3.62AlaTyr: 3.62 ± 0.093
0.0AlaXaa: 0.0 ± 0.0
Cys
1.81CysAla: 1.81 ± 0.887
0.0CysCys: 0.0 ± 0.0
0.0CysAsp: 0.0 ± 0.0
0.0CysGlu: 0.0 ± 0.0
0.0CysPhe: 0.0 ± 0.0
0.905CysGly: 0.905 ± 1.237
0.0CysHis: 0.0 ± 0.0
0.0CysIle: 0.0 ± 0.0
0.905CysLys: 0.905 ± 0.443
0.0CysLeu: 0.0 ± 0.0
0.0CysMet: 0.0 ± 0.0
0.0CysAsn: 0.0 ± 0.0
0.905CysPro: 0.905 ± 1.237
2.715CysGln: 2.715 ± 1.33
0.0CysArg: 0.0 ± 0.0
0.905CysSer: 0.905 ± 0.443
1.81CysThr: 1.81 ± 0.887
0.0CysVal: 0.0 ± 0.0
0.0CysTrp: 0.0 ± 0.0
0.0CysTyr: 0.0 ± 0.0
0.0CysXaa: 0.0 ± 0.0
Asp
1.81AspAla: 1.81 ± 0.794
0.905AspCys: 0.905 ± 0.443
5.43AspAsp: 5.43 ± 0.98
0.905AspGlu: 0.905 ± 0.443
0.905AspPhe: 0.905 ± 1.237
1.81AspGly: 1.81 ± 0.794
0.905AspHis: 0.905 ± 1.237
6.335AspIle: 6.335 ± 0.258
3.62AspLys: 3.62 ± 0.093
4.525AspLeu: 4.525 ± 2.217
3.62AspMet: 3.62 ± 0.093
0.0AspAsn: 0.0 ± 0.0
0.0AspPro: 0.0 ± 0.0
3.62AspGln: 3.62 ± 1.588
1.81AspArg: 1.81 ± 0.794
1.81AspSer: 1.81 ± 0.887
4.525AspThr: 4.525 ± 0.536
3.62AspVal: 3.62 ± 0.093
1.81AspTrp: 1.81 ± 0.794
0.905AspTyr: 0.905 ± 0.443
0.0AspXaa: 0.0 ± 0.0
Glu
2.715GluAla: 2.715 ± 0.351
0.905GluCys: 0.905 ± 1.237
3.62GluAsp: 3.62 ± 1.774
5.43GluGlu: 5.43 ± 0.98
0.905GluPhe: 0.905 ± 0.443
0.905GluGly: 0.905 ± 0.443
2.715GluHis: 2.715 ± 0.351
1.81GluIle: 1.81 ± 0.794
6.335GluLys: 6.335 ± 1.423
4.525GluLeu: 4.525 ± 0.536
1.81GluMet: 1.81 ± 0.887
2.715GluAsn: 2.715 ± 0.351
1.81GluPro: 1.81 ± 0.887
5.43GluGln: 5.43 ± 0.701
5.43GluArg: 5.43 ± 0.98
5.43GluSer: 5.43 ± 2.661
2.715GluThr: 2.715 ± 0.351
6.335GluVal: 6.335 ± 1.939
0.0GluTrp: 0.0 ± 0.0
2.715GluTyr: 2.715 ± 0.351
0.0GluXaa: 0.0 ± 0.0
Phe
2.715PheAla: 2.715 ± 1.33
0.905PheCys: 0.905 ± 1.237
1.81PheAsp: 1.81 ± 0.794
2.715PheGlu: 2.715 ± 0.351
1.81PhePhe: 1.81 ± 0.794
1.81PheGly: 1.81 ± 0.794
1.81PheHis: 1.81 ± 2.475
0.905PheIle: 0.905 ± 0.443
1.81PheLys: 1.81 ± 0.794
4.525PheLeu: 4.525 ± 1.145
0.905PheMet: 0.905 ± 0.443
1.81PheAsn: 1.81 ± 0.887
1.81PhePro: 1.81 ± 0.794
2.715PheGln: 2.715 ± 2.032
0.905PheArg: 0.905 ± 0.443
0.905PheSer: 0.905 ± 0.443
0.905PheThr: 0.905 ± 0.443
2.715PheVal: 2.715 ± 2.032
0.0PheTrp: 0.0 ± 0.0
0.905PheTyr: 0.905 ± 0.443
0.0PheXaa: 0.0 ± 0.0
Gly
4.525GlyAla: 4.525 ± 0.536
0.0GlyCys: 0.0 ± 0.0
1.81GlyAsp: 1.81 ± 2.475
6.335GlyGlu: 6.335 ± 0.258
0.905GlyPhe: 0.905 ± 0.443
5.43GlyGly: 5.43 ± 2.661
1.81GlyHis: 1.81 ± 0.794
1.81GlyIle: 1.81 ± 0.887
2.715GlyLys: 2.715 ± 1.33
6.335GlyLeu: 6.335 ± 3.62
4.525GlyMet: 4.525 ± 0.536
3.62GlyAsn: 3.62 ± 0.093
3.62GlyPro: 3.62 ± 1.774
5.43GlyGln: 5.43 ± 0.701
2.715GlyArg: 2.715 ± 1.33
4.525GlySer: 4.525 ± 0.536
1.81GlyThr: 1.81 ± 0.794
5.43GlyVal: 5.43 ± 0.701
3.62GlyTrp: 3.62 ± 1.588
2.715GlyTyr: 2.715 ± 1.33
0.0GlyXaa: 0.0 ± 0.0
His
1.81HisAla: 1.81 ± 0.794
0.0HisCys: 0.0 ± 0.0
0.905HisAsp: 0.905 ± 1.237
0.0HisGlu: 0.0 ± 0.0
0.905HisPhe: 0.905 ± 0.443
0.905HisGly: 0.905 ± 1.237
1.81HisHis: 1.81 ± 0.794
2.715HisIle: 2.715 ± 0.351
1.81HisLys: 1.81 ± 0.794
5.43HisLeu: 5.43 ± 0.701
0.0HisMet: 0.0 ± 0.0
0.0HisAsn: 0.0 ± 0.0
0.905HisPro: 0.905 ± 1.237
0.0HisGln: 0.0 ± 0.0
1.81HisArg: 1.81 ± 0.794
1.81HisSer: 1.81 ± 0.887
1.81HisThr: 1.81 ± 0.794
2.715HisVal: 2.715 ± 0.351
0.905HisTrp: 0.905 ± 0.443
0.905HisTyr: 0.905 ± 1.237
0.0HisXaa: 0.0 ± 0.0
Ile
1.81IleAla: 1.81 ± 0.887
0.0IleCys: 0.0 ± 0.0
2.715IleAsp: 2.715 ± 0.351
5.43IleGlu: 5.43 ± 0.701
2.715IlePhe: 2.715 ± 3.712
4.525IleGly: 4.525 ± 1.145
0.0IleHis: 0.0 ± 0.0
1.81IleIle: 1.81 ± 0.794
2.715IleLys: 2.715 ± 0.351
3.62IleLeu: 3.62 ± 0.093
3.62IleMet: 3.62 ± 1.774
2.715IleAsn: 2.715 ± 1.33
2.715IlePro: 2.715 ± 1.33
2.715IleGln: 2.715 ± 0.351
7.24IleArg: 7.24 ± 0.186
2.715IleSer: 2.715 ± 0.351
0.0IleThr: 0.0 ± 0.0
3.62IleVal: 3.62 ± 0.093
0.905IleTrp: 0.905 ± 0.443
0.0IleTyr: 0.0 ± 0.0
0.0IleXaa: 0.0 ± 0.0
Lys
0.905LysAla: 0.905 ± 0.443
0.905LysCys: 0.905 ± 0.443
3.62LysAsp: 3.62 ± 0.093
5.43LysGlu: 5.43 ± 4.063
1.81LysPhe: 1.81 ± 0.794
0.905LysGly: 0.905 ± 0.443
1.81LysHis: 1.81 ± 0.794
3.62LysIle: 3.62 ± 1.774
6.335LysLys: 6.335 ± 3.104
4.525LysLeu: 4.525 ± 2.217
1.81LysMet: 1.81 ± 0.794
2.715LysAsn: 2.715 ± 1.33
3.62LysPro: 3.62 ± 0.093
3.62LysGln: 3.62 ± 0.093
9.05LysArg: 9.05 ± 1.072
7.24LysSer: 7.24 ± 0.186
3.62LysThr: 3.62 ± 0.093
1.81LysVal: 1.81 ± 0.794
0.0LysTrp: 0.0 ± 0.0
1.81LysTyr: 1.81 ± 0.887
0.0LysXaa: 0.0 ± 0.0
Leu
7.24LeuAla: 7.24 ± 0.186
0.905LeuCys: 0.905 ± 0.443
2.715LeuAsp: 2.715 ± 0.351
3.62LeuGlu: 3.62 ± 1.774
0.905LeuPhe: 0.905 ± 1.237
6.335LeuGly: 6.335 ± 0.258
3.62LeuHis: 3.62 ± 1.588
4.525LeuIle: 4.525 ± 2.826
4.525LeuLys: 4.525 ± 0.536
2.715LeuLeu: 2.715 ± 0.351
2.715LeuMet: 2.715 ± 3.712
4.525LeuAsn: 4.525 ± 2.217
6.335LeuPro: 6.335 ± 1.423
4.525LeuGln: 4.525 ± 1.145
3.62LeuArg: 3.62 ± 3.269
3.62LeuSer: 3.62 ± 0.093
2.715LeuThr: 2.715 ± 1.33
6.335LeuVal: 6.335 ± 0.258
1.81LeuTrp: 1.81 ± 0.794
6.335LeuTyr: 6.335 ± 0.258
0.0LeuXaa: 0.0 ± 0.0
Met
4.525MetAla: 4.525 ± 2.217
0.905MetCys: 0.905 ± 0.443
1.81MetAsp: 1.81 ± 0.887
4.525MetGlu: 4.525 ± 1.145
0.0MetPhe: 0.0 ± 0.0
2.715MetGly: 2.715 ± 0.351
0.0MetHis: 0.0 ± 0.0
4.525MetIle: 4.525 ± 1.145
1.81MetLys: 1.81 ± 0.887
3.62MetLeu: 3.62 ± 1.588
0.905MetMet: 0.905 ± 1.237
0.905MetAsn: 0.905 ± 1.237
1.81MetPro: 1.81 ± 0.794
2.715MetGln: 2.715 ± 1.33
1.81MetArg: 1.81 ± 0.794
5.43MetSer: 5.43 ± 0.98
3.62MetThr: 3.62 ± 1.588
0.905MetVal: 0.905 ± 0.443
1.81MetTrp: 1.81 ± 0.794
0.905MetTyr: 0.905 ± 0.443
0.0MetXaa: 0.0 ± 0.0
Asn
4.525AsnAla: 4.525 ± 2.217
0.0AsnCys: 0.0 ± 0.0
1.81AsnAsp: 1.81 ± 0.887
0.905AsnGlu: 0.905 ± 0.443
1.81AsnPhe: 1.81 ± 0.794
2.715AsnGly: 2.715 ± 1.33
0.905AsnHis: 0.905 ± 1.237
2.715AsnIle: 2.715 ± 1.33
0.905AsnLys: 0.905 ± 0.443
3.62AsnLeu: 3.62 ± 1.774
0.0AsnMet: 0.0 ± 0.395
0.905AsnAsn: 0.905 ± 0.443
2.715AsnPro: 2.715 ± 1.33
1.81AsnGln: 1.81 ± 0.887
0.905AsnArg: 0.905 ± 0.443
2.715AsnSer: 2.715 ± 0.351
1.81AsnThr: 1.81 ± 0.794
1.81AsnVal: 1.81 ± 0.887
0.905AsnTrp: 0.905 ± 0.443
0.905AsnTyr: 0.905 ± 0.443
0.0AsnXaa: 0.0 ± 0.0
Pro
3.62ProAla: 3.62 ± 1.588
0.0ProCys: 0.0 ± 0.0
0.905ProAsp: 0.905 ± 0.443
2.715ProGlu: 2.715 ± 0.351
1.81ProPhe: 1.81 ± 0.794
1.81ProGly: 1.81 ± 0.794
0.0ProHis: 0.0 ± 0.0
0.0ProIle: 0.0 ± 0.0
2.715ProLys: 2.715 ± 1.33
3.62ProLeu: 3.62 ± 1.774
1.81ProMet: 1.81 ± 0.794
2.715ProAsn: 2.715 ± 1.33
3.62ProPro: 3.62 ± 0.093
0.905ProGln: 0.905 ± 0.443
2.715ProArg: 2.715 ± 0.351
5.43ProSer: 5.43 ± 0.701
3.62ProThr: 3.62 ± 1.774
3.62ProVal: 3.62 ± 1.774
1.81ProTrp: 1.81 ± 2.475
1.81ProTyr: 1.81 ± 0.887
0.0ProXaa: 0.0 ± 0.0
Gln
2.715GlnAla: 2.715 ± 1.33
0.0GlnCys: 0.0 ± 0.0
1.81GlnAsp: 1.81 ± 0.794
2.715GlnGlu: 2.715 ± 1.33
1.81GlnPhe: 1.81 ± 0.887
2.715GlnGly: 2.715 ± 0.351
0.0GlnHis: 0.0 ± 0.0
2.715GlnIle: 2.715 ± 0.351
3.62GlnLys: 3.62 ± 1.588
5.43GlnLeu: 5.43 ± 0.701
5.43GlnMet: 5.43 ± 2.661
1.81GlnAsn: 1.81 ± 0.887
2.715GlnPro: 2.715 ± 3.712
0.905GlnGln: 0.905 ± 1.237
3.62GlnArg: 3.62 ± 3.269
5.43GlnSer: 5.43 ± 0.98
4.525GlnThr: 4.525 ± 2.217
3.62GlnVal: 3.62 ± 0.093
0.0GlnTrp: 0.0 ± 0.0
0.905GlnTyr: 0.905 ± 1.237
0.0GlnXaa: 0.0 ± 0.0
Arg
4.525ArgAla: 4.525 ± 1.145
0.0ArgCys: 0.0 ± 0.0
1.81ArgAsp: 1.81 ± 0.794
3.62ArgGlu: 3.62 ± 0.093
3.62ArgPhe: 3.62 ± 1.588
5.43ArgGly: 5.43 ± 0.701
0.905ArgHis: 0.905 ± 1.237
2.715ArgIle: 2.715 ± 0.351
5.43ArgLys: 5.43 ± 0.701
6.335ArgLeu: 6.335 ± 1.939
2.715ArgMet: 2.715 ± 0.427
4.525ArgAsn: 4.525 ± 2.217
0.905ArgPro: 0.905 ± 0.443
0.905ArgGln: 0.905 ± 0.443
2.715ArgArg: 2.715 ± 2.032
3.62ArgSer: 3.62 ± 0.093
3.62ArgThr: 3.62 ± 0.093
0.0ArgVal: 0.0 ± 0.0
0.905ArgTrp: 0.905 ± 1.237
0.905ArgTyr: 0.905 ± 1.237
0.0ArgXaa: 0.0 ± 0.0
Ser
4.525SerAla: 4.525 ± 2.217
0.905SerCys: 0.905 ± 0.443
4.525SerAsp: 4.525 ± 1.145
5.43SerGlu: 5.43 ± 2.661
2.715SerPhe: 2.715 ± 1.33
9.955SerGly: 9.955 ± 1.516
2.715SerHis: 2.715 ± 1.33
4.525SerIle: 4.525 ± 1.145
5.43SerLys: 5.43 ± 2.661
8.145SerLeu: 8.145 ± 2.31
4.525SerMet: 4.525 ± 0.536
3.62SerAsn: 3.62 ± 0.093
4.525SerPro: 4.525 ± 0.536
2.715SerGln: 2.715 ± 0.351
1.81SerArg: 1.81 ± 0.794
11.765SerSer: 11.765 ± 2.403
4.525SerThr: 4.525 ± 2.217
4.525SerVal: 4.525 ± 0.536
0.905SerTrp: 0.905 ± 1.237
3.62SerTyr: 3.62 ± 0.093
0.0SerXaa: 0.0 ± 0.0
Thr
2.715ThrAla: 2.715 ± 1.33
0.905ThrCys: 0.905 ± 0.443
2.715ThrAsp: 2.715 ± 1.33
2.715ThrGlu: 2.715 ± 0.351
4.525ThrPhe: 4.525 ± 1.145
2.715ThrGly: 2.715 ± 1.33
1.81ThrHis: 1.81 ± 0.887
0.905ThrIle: 0.905 ± 0.443
3.62ThrLys: 3.62 ± 0.093
4.525ThrLeu: 4.525 ± 2.826
2.715ThrMet: 2.715 ± 2.032
0.0ThrAsn: 0.0 ± 0.0
3.62ThrPro: 3.62 ± 1.774
3.62ThrGln: 3.62 ± 0.093
1.81ThrArg: 1.81 ± 0.887
9.05ThrSer: 9.05 ± 4.434
1.81ThrThr: 1.81 ± 0.887
1.81ThrVal: 1.81 ± 2.475
0.0ThrTrp: 0.0 ± 0.0
0.0ThrTyr: 0.0 ± 0.0
0.0ThrXaa: 0.0 ± 0.0
Val
3.62ValAla: 3.62 ± 0.093
0.0ValCys: 0.0 ± 0.0
2.715ValAsp: 2.715 ± 0.351
2.715ValGlu: 2.715 ± 1.33
0.0ValPhe: 0.0 ± 0.0
9.955ValGly: 9.955 ± 1.516
2.715ValHis: 2.715 ± 1.33
3.62ValIle: 3.62 ± 1.774
1.81ValLys: 1.81 ± 2.475
3.62ValLeu: 3.62 ± 3.269
1.81ValMet: 1.81 ± 0.794
1.81ValAsn: 1.81 ± 0.887
0.905ValPro: 0.905 ± 1.237
1.81ValGln: 1.81 ± 0.887
4.525ValArg: 4.525 ± 2.826
5.43ValSer: 5.43 ± 2.382
3.62ValThr: 3.62 ± 0.093
3.62ValVal: 3.62 ± 0.093
0.0ValTrp: 0.0 ± 0.0
1.81ValTyr: 1.81 ± 0.794
0.0ValXaa: 0.0 ± 0.0
Trp
1.81TrpAla: 1.81 ± 0.794
0.905TrpCys: 0.905 ± 0.443
1.81TrpAsp: 1.81 ± 0.794
0.905TrpGlu: 0.905 ± 1.237
0.0TrpPhe: 0.0 ± 0.0
0.0TrpGly: 0.0 ± 0.0
0.0TrpHis: 0.0 ± 0.0
0.0TrpIle: 0.0 ± 0.0
3.62TrpLys: 3.62 ± 0.093
0.905TrpLeu: 0.905 ± 1.237
0.905TrpMet: 0.905 ± 1.237
0.0TrpAsn: 0.0 ± 0.0
0.0TrpPro: 0.0 ± 0.0
0.905TrpGln: 0.905 ± 0.443
0.905TrpArg: 0.905 ± 1.237
3.62TrpSer: 3.62 ± 0.093
1.81TrpThr: 1.81 ± 2.475
0.0TrpVal: 0.0 ± 0.0
0.905TrpTrp: 0.905 ± 0.443
0.0TrpTyr: 0.0 ± 0.0
0.0TrpXaa: 0.0 ± 0.0
Tyr
1.81TyrAla: 1.81 ± 0.887
0.905TyrCys: 0.905 ± 0.443
3.62TyrAsp: 3.62 ± 0.093
4.525TyrGlu: 4.525 ± 2.217
2.715TyrPhe: 2.715 ± 0.351
0.905TyrGly: 0.905 ± 0.443
0.905TyrHis: 0.905 ± 1.237
0.0TyrIle: 0.0 ± 0.0
2.715TyrLys: 2.715 ± 2.032
1.81TyrLeu: 1.81 ± 0.794
0.905TyrMet: 0.905 ± 0.443
0.0TyrAsn: 0.0 ± 0.0
0.905TyrPro: 0.905 ± 0.443
1.81TyrGln: 1.81 ± 0.794
0.0TyrArg: 0.0 ± 0.0
2.715TyrSer: 2.715 ± 1.33
1.81TyrThr: 1.81 ± 0.887
0.905TyrVal: 0.905 ± 1.237
1.81TyrTrp: 1.81 ± 0.794
1.81TyrTyr: 1.81 ± 0.887
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 2 proteins (1106 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski