Amino acid dipepetide frequency for Hubei earwig virus 3

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
4.921AlaAla: 4.921 ± 0.333
1.476AlaCys: 1.476 ± 0.42
2.707AlaAsp: 2.707 ± 0.497
1.722AlaGlu: 1.722 ± 0.157
3.445AlaPhe: 3.445 ± 0.887
3.445AlaGly: 3.445 ± 0.087
1.476AlaHis: 1.476 ± 0.42
5.167AlaIle: 5.167 ± 0.07
3.199AlaLys: 3.199 ± 0.223
5.659AlaLeu: 5.659 ± 2.058
1.476AlaMet: 1.476 ± 0.42
4.429AlaAsn: 4.429 ± 1.541
1.476AlaPro: 1.476 ± 0.38
1.969AlaGln: 1.969 ± 0.107
2.461AlaArg: 2.461 ± 1.034
3.199AlaSer: 3.199 ± 0.624
3.691AlaThr: 3.691 ± 0.45
4.183AlaVal: 4.183 ± 0.323
1.23AlaTrp: 1.23 ± 0.117
2.461AlaTyr: 2.461 ± 0.167
0.0AlaXaa: 0.0 ± 0.0
Cys
0.492CysAla: 0.492 ± 0.127
0.738CysCys: 0.738 ± 0.01
1.23CysAsp: 1.23 ± 0.117
0.738CysGlu: 0.738 ± 0.01
0.984CysPhe: 0.984 ± 0.147
0.984CysGly: 0.984 ± 0.547
0.246CysHis: 0.246 ± 0.137
1.476CysIle: 1.476 ± 0.82
0.738CysLys: 0.738 ± 0.41
1.476CysLeu: 1.476 ± 0.02
0.246CysMet: 0.246 ± 0.263
0.492CysAsn: 0.492 ± 0.127
0.0CysPro: 0.0 ± 0.0
0.492CysGln: 0.492 ± 0.273
0.0CysArg: 0.0 ± 0.0
1.722CysSer: 1.722 ± 0.157
0.984CysThr: 0.984 ± 0.547
1.23CysVal: 1.23 ± 0.684
0.0CysTrp: 0.0 ± 0.0
0.246CysTyr: 0.246 ± 0.263
0.0CysXaa: 0.0 ± 0.0
Asp
3.691AspAla: 3.691 ± 0.35
0.738AspCys: 0.738 ± 0.41
4.429AspAsp: 4.429 ± 0.74
2.953AspGlu: 2.953 ± 0.44
2.953AspPhe: 2.953 ± 0.44
2.707AspGly: 2.707 ± 1.104
2.707AspHis: 2.707 ± 0.897
3.445AspIle: 3.445 ± 1.514
5.167AspLys: 5.167 ± 0.87
7.628AspLeu: 7.628 ± 0.564
1.722AspMet: 1.722 ± 0.157
3.199AspAsn: 3.199 ± 0.624
1.969AspPro: 1.969 ± 0.107
2.461AspGln: 2.461 ± 0.233
1.722AspArg: 1.722 ± 0.157
3.937AspSer: 3.937 ± 0.187
3.445AspThr: 3.445 ± 0.313
3.691AspVal: 3.691 ± 0.75
0.738AspTrp: 0.738 ± 0.39
1.722AspTyr: 1.722 ± 0.243
0.0AspXaa: 0.0 ± 0.0
Glu
2.707GluAla: 2.707 ± 0.303
0.492GluCys: 0.492 ± 0.127
2.215GluAsp: 2.215 ± 0.37
2.707GluGlu: 2.707 ± 1.104
1.969GluPhe: 1.969 ± 1.094
3.199GluGly: 3.199 ± 0.223
1.969GluHis: 1.969 ± 0.694
4.429GluIle: 4.429 ± 0.86
1.969GluLys: 1.969 ± 0.694
4.921GluLeu: 4.921 ± 1.134
1.722GluMet: 1.722 ± 0.157
1.23GluAsn: 1.23 ± 0.517
0.738GluPro: 0.738 ± 0.01
2.953GluGln: 2.953 ± 0.84
1.23GluArg: 1.23 ± 0.684
4.921GluSer: 4.921 ± 0.067
4.921GluThr: 4.921 ± 1.267
2.461GluVal: 2.461 ± 0.567
0.246GluTrp: 0.246 ± 0.137
1.476GluTyr: 1.476 ± 0.02
0.0GluXaa: 0.0 ± 0.0
Phe
3.445PheAla: 3.445 ± 0.887
0.492PheCys: 0.492 ± 0.127
4.675PheAsp: 4.675 ± 0.597
3.691PheGlu: 3.691 ± 1.25
1.969PhePhe: 1.969 ± 1.094
2.461PheGly: 2.461 ± 0.233
0.492PheHis: 0.492 ± 0.127
3.445PheIle: 3.445 ± 0.887
4.429PheLys: 4.429 ± 2.461
4.921PheLeu: 4.921 ± 1.134
0.738PheMet: 0.738 ± 0.41
3.937PheAsn: 3.937 ± 0.187
2.215PhePro: 2.215 ± 0.77
3.199PheGln: 3.199 ± 0.577
1.23PheArg: 1.23 ± 0.283
3.691PheSer: 3.691 ± 0.45
4.675PheThr: 4.675 ± 0.197
3.445PheVal: 3.445 ± 0.487
0.246PheTrp: 0.246 ± 0.137
2.215PheTyr: 2.215 ± 0.37
0.0PheXaa: 0.0 ± 0.0
Gly
2.953GlyAla: 2.953 ± 0.36
1.23GlyCys: 1.23 ± 0.117
2.215GlyAsp: 2.215 ± 0.03
1.476GlyGlu: 1.476 ± 0.82
1.969GlyPhe: 1.969 ± 0.694
2.707GlyGly: 2.707 ± 0.097
0.984GlyHis: 0.984 ± 0.147
4.183GlyIle: 4.183 ± 0.077
1.969GlyLys: 1.969 ± 1.094
3.445GlyLeu: 3.445 ± 1.287
0.246GlyMet: 0.246 ± 0.137
2.707GlyAsn: 2.707 ± 0.303
0.984GlyPro: 0.984 ± 0.654
1.722GlyGln: 1.722 ± 1.044
1.23GlyArg: 1.23 ± 0.283
3.691GlySer: 3.691 ± 0.45
4.183GlyThr: 4.183 ± 1.677
1.969GlyVal: 1.969 ± 1.307
0.246GlyTrp: 0.246 ± 0.137
1.969GlyTyr: 1.969 ± 0.293
0.0GlyXaa: 0.0 ± 0.0
His
1.23HisAla: 1.23 ± 0.917
0.246HisCys: 0.246 ± 0.263
1.23HisAsp: 1.23 ± 0.917
0.738HisGlu: 0.738 ± 0.01
1.476HisPhe: 1.476 ± 0.42
0.492HisGly: 0.492 ± 0.273
0.984HisHis: 0.984 ± 0.147
1.23HisIle: 1.23 ± 0.283
0.492HisLys: 0.492 ± 0.273
2.461HisLeu: 2.461 ± 0.567
0.738HisMet: 0.738 ± 0.41
1.969HisAsn: 1.969 ± 0.107
1.969HisPro: 1.969 ± 0.907
1.476HisGln: 1.476 ± 0.42
1.722HisArg: 1.722 ± 0.557
2.215HisSer: 2.215 ± 0.37
1.722HisThr: 1.722 ± 0.243
2.215HisVal: 2.215 ± 0.03
0.246HisTrp: 0.246 ± 0.137
1.476HisTyr: 1.476 ± 0.38
0.0HisXaa: 0.0 ± 0.0
Ile
3.691IleAla: 3.691 ± 0.35
1.722IleCys: 1.722 ± 0.557
4.675IleAsp: 4.675 ± 1.004
3.937IleGlu: 3.937 ± 0.614
4.675IlePhe: 4.675 ± 1.797
2.461IleGly: 2.461 ± 0.233
1.476IleHis: 1.476 ± 0.42
3.445IleIle: 3.445 ± 0.313
2.953IleLys: 2.953 ± 0.84
4.675IleLeu: 4.675 ± 0.597
0.984IleMet: 0.984 ± 0.253
4.183IleAsn: 4.183 ± 0.077
4.429IlePro: 4.429 ± 0.46
2.215IleGln: 2.215 ± 0.37
1.722IleArg: 1.722 ± 0.157
5.906IleSer: 5.906 ± 0.88
3.937IleThr: 3.937 ± 0.587
4.429IleVal: 4.429 ± 0.34
0.492IleTrp: 0.492 ± 0.127
2.953IleTyr: 2.953 ± 1.24
0.0IleXaa: 0.0 ± 0.0
Lys
2.953LysAla: 2.953 ± 0.44
0.492LysCys: 0.492 ± 0.273
3.691LysAsp: 3.691 ± 0.45
4.675LysGlu: 4.675 ± 1.797
3.937LysPhe: 3.937 ± 1.014
0.738LysGly: 0.738 ± 0.01
2.707LysHis: 2.707 ± 0.097
3.199LysIle: 3.199 ± 0.577
4.675LysLys: 4.675 ± 1.397
6.152LysLeu: 6.152 ± 1.417
0.984LysMet: 0.984 ± 0.147
3.937LysAsn: 3.937 ± 0.213
2.461LysPro: 2.461 ± 0.233
3.199LysGln: 3.199 ± 0.577
1.476LysArg: 1.476 ± 0.38
4.183LysSer: 4.183 ± 1.524
4.429LysThr: 4.429 ± 0.06
3.199LysVal: 3.199 ± 0.977
0.984LysTrp: 0.984 ± 0.253
3.199LysTyr: 3.199 ± 0.977
0.0LysXaa: 0.0 ± 0.0
Leu
6.152LeuAla: 6.152 ± 0.217
1.23LeuCys: 1.23 ± 0.517
4.429LeuAsp: 4.429 ± 1.661
3.199LeuGlu: 3.199 ± 0.223
5.413LeuPhe: 5.413 ± 0.607
3.199LeuGly: 3.199 ± 1.424
2.707LeuHis: 2.707 ± 0.497
6.398LeuIle: 6.398 ± 1.154
5.906LeuLys: 5.906 ± 0.32
6.89LeuLeu: 6.89 ± 1.027
1.722LeuMet: 1.722 ± 0.557
3.691LeuAsn: 3.691 ± 0.45
3.691LeuPro: 3.691 ± 0.75
5.659LeuGln: 5.659 ± 0.457
4.675LeuArg: 4.675 ± 0.597
8.612LeuSer: 8.612 ± 0.417
7.382LeuThr: 7.382 ± 1.101
4.675LeuVal: 4.675 ± 1.804
0.492LeuTrp: 0.492 ± 0.127
4.429LeuTyr: 4.429 ± 0.06
0.0LeuXaa: 0.0 ± 0.0
Met
2.215MetAla: 2.215 ± 0.83
0.492MetCys: 0.492 ± 0.273
0.0MetAsp: 0.0 ± 0.0
0.984MetGlu: 0.984 ± 0.253
1.722MetPhe: 1.722 ± 0.644
0.492MetGly: 0.492 ± 0.127
0.738MetHis: 0.738 ± 0.39
0.492MetIle: 0.492 ± 0.273
0.738MetLys: 0.738 ± 0.41
1.722MetLeu: 1.722 ± 0.243
0.492MetMet: 0.492 ± 0.273
2.461MetAsn: 2.461 ± 0.167
0.738MetPro: 0.738 ± 0.41
0.738MetGln: 0.738 ± 0.41
1.23MetArg: 1.23 ± 0.117
1.722MetSer: 1.722 ± 0.644
1.23MetThr: 1.23 ± 0.684
1.23MetVal: 1.23 ± 0.283
0.0MetTrp: 0.0 ± 0.0
0.984MetTyr: 0.984 ± 0.147
0.0MetXaa: 0.0 ± 0.0
Asn
3.937AsnAla: 3.937 ± 0.614
0.492AsnCys: 0.492 ± 0.273
2.707AsnAsp: 2.707 ± 1.297
1.23AsnGlu: 1.23 ± 0.117
3.691AsnPhe: 3.691 ± 0.05
2.707AsnGly: 2.707 ± 0.303
1.23AsnHis: 1.23 ± 0.117
5.167AsnIle: 5.167 ± 0.33
5.167AsnLys: 5.167 ± 0.87
4.921AsnLeu: 4.921 ± 0.333
0.738AsnMet: 0.738 ± 0.01
4.675AsnAsn: 4.675 ± 0.203
5.906AsnPro: 5.906 ± 1.921
1.476AsnGln: 1.476 ± 1.18
2.461AsnArg: 2.461 ± 1.367
3.937AsnSer: 3.937 ± 0.987
3.691AsnThr: 3.691 ± 0.05
5.413AsnVal: 5.413 ± 0.594
0.492AsnTrp: 0.492 ± 0.273
2.953AsnTyr: 2.953 ± 1.961
0.0AsnXaa: 0.0 ± 0.0
Pro
3.937ProAla: 3.937 ± 0.614
0.984ProCys: 0.984 ± 0.547
2.461ProAsp: 2.461 ± 0.233
1.969ProGlu: 1.969 ± 0.507
1.969ProPhe: 1.969 ± 0.507
1.969ProGly: 1.969 ± 0.507
1.476ProHis: 1.476 ± 0.42
3.199ProIle: 3.199 ± 0.177
1.23ProLys: 1.23 ± 0.283
4.183ProLeu: 4.183 ± 0.877
1.23ProMet: 1.23 ± 0.117
2.461ProAsn: 2.461 ± 0.634
3.445ProPro: 3.445 ± 1.287
1.476ProGln: 1.476 ± 0.02
1.969ProArg: 1.969 ± 0.107
3.199ProSer: 3.199 ± 1.424
5.413ProThr: 5.413 ± 2.194
2.707ProVal: 2.707 ± 0.097
0.0ProTrp: 0.0 ± 0.0
1.722ProTyr: 1.722 ± 0.243
0.0ProXaa: 0.0 ± 0.0
Gln
1.23GlnAla: 1.23 ± 0.117
0.246GlnCys: 0.246 ± 0.137
2.215GlnAsp: 2.215 ± 0.43
1.23GlnGlu: 1.23 ± 0.684
2.707GlnPhe: 2.707 ± 0.303
1.23GlnGly: 1.23 ± 0.517
1.969GlnHis: 1.969 ± 0.107
2.707GlnIle: 2.707 ± 0.497
3.445GlnLys: 3.445 ± 0.887
5.413GlnLeu: 5.413 ± 0.594
1.23GlnMet: 1.23 ± 0.362
3.445GlnAsn: 3.445 ± 0.887
1.23GlnPro: 1.23 ± 0.117
3.691GlnGln: 3.691 ± 1.151
1.722GlnArg: 1.722 ± 0.644
3.691GlnSer: 3.691 ± 0.45
3.937GlnThr: 3.937 ± 1.414
2.953GlnVal: 2.953 ± 0.84
0.738GlnTrp: 0.738 ± 0.41
1.969GlnTyr: 1.969 ± 0.107
0.0GlnXaa: 0.0 ± 0.0
Arg
1.23ArgAla: 1.23 ± 0.517
0.0ArgCys: 0.0 ± 0.0
2.215ArgAsp: 2.215 ± 0.83
1.969ArgGlu: 1.969 ± 0.107
2.953ArgPhe: 2.953 ± 0.36
1.969ArgGly: 1.969 ± 0.107
0.984ArgHis: 0.984 ± 0.147
2.707ArgIle: 2.707 ± 0.704
2.707ArgLys: 2.707 ± 0.303
3.691ArgLeu: 3.691 ± 0.75
1.23ArgMet: 1.23 ± 0.117
2.215ArgAsn: 2.215 ± 0.03
3.937ArgPro: 3.937 ± 0.213
1.969ArgGln: 1.969 ± 0.694
1.476ArgArg: 1.476 ± 0.42
2.215ArgSer: 2.215 ± 0.43
2.215ArgThr: 2.215 ± 0.43
1.969ArgVal: 1.969 ± 0.293
0.246ArgTrp: 0.246 ± 0.137
1.476ArgTyr: 1.476 ± 0.02
0.0ArgXaa: 0.0 ± 0.0
Ser
3.937SerAla: 3.937 ± 0.614
0.984SerCys: 0.984 ± 0.147
4.183SerAsp: 4.183 ± 1.124
4.429SerGlu: 4.429 ± 0.06
5.659SerPhe: 5.659 ± 1.144
3.691SerGly: 3.691 ± 0.35
1.23SerHis: 1.23 ± 0.517
3.691SerIle: 3.691 ± 0.05
5.659SerLys: 5.659 ± 0.857
8.366SerLeu: 8.366 ± 0.247
2.461SerMet: 2.461 ± 0.132
3.445SerAsn: 3.445 ± 0.887
3.445SerPro: 3.445 ± 0.714
2.953SerGln: 2.953 ± 0.36
3.445SerArg: 3.445 ± 0.087
6.152SerSer: 6.152 ± 0.183
4.183SerThr: 4.183 ± 0.477
4.675SerVal: 4.675 ± 0.604
0.738SerTrp: 0.738 ± 0.41
3.199SerTyr: 3.199 ± 0.977
0.0SerXaa: 0.0 ± 0.0
Thr
3.937ThrAla: 3.937 ± 0.614
0.246ThrCys: 0.246 ± 0.137
5.167ThrAsp: 5.167 ± 0.87
3.691ThrGlu: 3.691 ± 0.05
3.937ThrPhe: 3.937 ± 0.987
2.461ThrGly: 2.461 ± 0.634
1.476ThrHis: 1.476 ± 0.38
4.429ThrIle: 4.429 ± 1.541
4.183ThrLys: 4.183 ± 0.724
7.136ThrLeu: 7.136 ± 0.437
0.492ThrMet: 0.492 ± 0.273
5.659ThrAsn: 5.659 ± 0.744
3.445ThrPro: 3.445 ± 1.287
3.691ThrGln: 3.691 ± 1.151
4.429ThrArg: 4.429 ± 0.74
5.906ThrSer: 5.906 ± 0.72
5.413ThrThr: 5.413 ± 2.194
3.445ThrVal: 3.445 ± 1.687
0.0ThrTrp: 0.0 ± 0.0
2.953ThrTyr: 2.953 ± 0.84
0.0ThrXaa: 0.0 ± 0.0
Val
3.937ValAla: 3.937 ± 1.014
1.476ValCys: 1.476 ± 0.42
6.644ValAsp: 6.644 ± 0.31
3.199ValGlu: 3.199 ± 0.577
2.215ValPhe: 2.215 ± 0.43
3.691ValGly: 3.691 ± 0.75
0.246ValHis: 0.246 ± 0.263
3.691ValIle: 3.691 ± 0.45
3.445ValLys: 3.445 ± 0.087
3.691ValLeu: 3.691 ± 0.75
0.738ValMet: 0.738 ± 0.39
5.659ValAsn: 5.659 ± 0.343
3.445ValPro: 3.445 ± 0.487
4.183ValGln: 4.183 ± 0.877
2.707ValArg: 2.707 ± 0.704
4.675ValSer: 4.675 ± 1.404
2.953ValThr: 2.953 ± 0.04
4.183ValVal: 4.183 ± 0.724
0.0ValTrp: 0.0 ± 0.0
0.738ValTyr: 0.738 ± 0.01
0.0ValXaa: 0.0 ± 0.0
Trp
0.492TrpAla: 0.492 ± 0.127
0.0TrpCys: 0.0 ± 0.0
0.246TrpAsp: 0.246 ± 0.137
0.738TrpGlu: 0.738 ± 0.39
0.246TrpPhe: 0.246 ± 0.137
0.246TrpGly: 0.246 ± 0.137
0.246TrpHis: 0.246 ± 0.137
0.492TrpIle: 0.492 ± 0.273
0.492TrpLys: 0.492 ± 0.273
0.492TrpLeu: 0.492 ± 0.273
0.246TrpMet: 0.246 ± 0.263
0.984TrpAsn: 0.984 ± 0.253
0.246TrpPro: 0.246 ± 0.137
0.246TrpGln: 0.246 ± 0.137
0.492TrpArg: 0.492 ± 0.273
0.492TrpSer: 0.492 ± 0.273
0.246TrpThr: 0.246 ± 0.263
0.492TrpVal: 0.492 ± 0.127
0.0TrpTrp: 0.0 ± 0.0
0.246TrpTyr: 0.246 ± 0.137
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.707TyrAla: 2.707 ± 0.303
0.738TyrCys: 0.738 ± 0.41
3.691TyrAsp: 3.691 ± 0.05
3.199TyrGlu: 3.199 ± 0.977
1.722TyrPhe: 1.722 ± 1.044
1.23TyrGly: 1.23 ± 0.684
0.984TyrHis: 0.984 ± 0.147
1.969TyrIle: 1.969 ± 0.293
2.707TyrLys: 2.707 ± 0.097
2.707TyrLeu: 2.707 ± 0.497
0.738TyrMet: 0.738 ± 0.01
2.215TyrAsn: 2.215 ± 0.03
1.23TyrPro: 1.23 ± 0.517
1.476TyrGln: 1.476 ± 0.38
1.969TyrArg: 1.969 ± 0.107
2.461TyrSer: 2.461 ± 0.233
3.445TyrThr: 3.445 ± 0.714
2.953TyrVal: 2.953 ± 0.44
0.246TyrTrp: 0.246 ± 0.137
2.707TyrTyr: 2.707 ± 0.303
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 2 proteins (4065 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski