Amino acid dipepetide frequency for Gordonibacter pamelaeae 7-10-1-b

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	15.49AlaAla: 15.49 ± 0.244	2.311AlaCys: 2.311 ± 0.071	7.0AlaAsp: 7.0 ± 0.126	7.692AlaGlu: 7.692 ± 0.132	4.677AlaPhe: 4.677 ± 0.115	9.438AlaGly: 9.438 ± 0.163	2.123AlaHis: 2.123 ± 0.067	5.435AlaIle: 5.435 ± 0.11	4.447AlaLys: 4.447 ± 0.096	11.898AlaLeu: 11.898 ± 0.189	3.149AlaMet: 3.149 ± 0.077	2.944AlaAsn: 2.944 ± 0.078	4.249AlaPro: 4.249 ± 0.098	3.408AlaGln: 3.408 ± 0.091	6.886AlaArg: 6.886 ± 0.133	6.411AlaSer: 6.411 ± 0.119	5.335AlaThr: 5.335 ± 0.109	8.964AlaVal: 8.964 ± 0.156	1.45AlaTrp: 1.45 ± 0.053	3.284AlaTyr: 3.284 ± 0.08	0.0AlaXaa: 0.0 ± 0.0
Cys	1.826CysAla: 1.826 ± 0.057	0.286CysCys: 0.286 ± 0.023	0.961CysAsp: 0.961 ± 0.04	0.929CysGlu: 0.929 ± 0.042	0.601CysPhe: 0.601 ± 0.031	1.69CysGly: 1.69 ± 0.054	0.406CysHis: 0.406 ± 0.028	0.829CysIle: 0.829 ± 0.036	0.574CysLys: 0.574 ± 0.036	1.416CysLeu: 1.416 ± 0.051	0.481CysMet: 0.481 ± 0.028	0.42CysAsn: 0.42 ± 0.025	0.838CysPro: 0.838 ± 0.048	0.359CysGln: 0.359 ± 0.024	0.902CysArg: 0.902 ± 0.037	0.863CysSer: 0.863 ± 0.046	0.861CysThr: 0.861 ± 0.042	1.284CysVal: 1.284 ± 0.048	0.21CysTrp: 0.21 ± 0.02	0.477CysTyr: 0.477 ± 0.029	0.0CysXaa: 0.0 ± 0.0
Asp	7.594AspAla: 7.594 ± 0.144	0.702AspCys: 0.702 ± 0.04	3.851AspAsp: 3.851 ± 0.097	5.521AspGlu: 5.521 ± 0.106	2.452AspPhe: 2.452 ± 0.063	5.656AspGly: 5.656 ± 0.14	1.017AspHis: 1.017 ± 0.042	3.191AspIle: 3.191 ± 0.085	2.127AspLys: 2.127 ± 0.057	5.57AspLeu: 5.57 ± 0.1	1.497AspMet: 1.497 ± 0.057	1.445AspAsn: 1.445 ± 0.045	3.299AspPro: 3.299 ± 0.084	1.472AspGln: 1.472 ± 0.051	3.435AspArg: 3.435 ± 0.098	2.472AspSer: 2.472 ± 0.07	2.584AspThr: 2.584 ± 0.067	4.795AspVal: 4.795 ± 0.095	0.805AspTrp: 0.805 ± 0.038	1.942AspTyr: 1.942 ± 0.056	0.0AspXaa: 0.0 ± 0.0
Glu	7.954GluAla: 7.954 ± 0.133	0.744GluCys: 0.744 ± 0.038	3.793GluAsp: 3.793 ± 0.098	4.841GluGlu: 4.841 ± 0.122	2.328GluPhe: 2.328 ± 0.058	5.782GluGly: 5.782 ± 0.112	1.516GluHis: 1.516 ± 0.056	3.039GluIle: 3.039 ± 0.08	3.161GluLys: 3.161 ± 0.09	6.487GluLeu: 6.487 ± 0.126	1.751GluMet: 1.751 ± 0.057	2.167GluAsn: 2.167 ± 0.061	2.805GluPro: 2.805 ± 0.073	2.42GluGln: 2.42 ± 0.067	5.374GluArg: 5.374 ± 0.113	3.066GluSer: 3.066 ± 0.074	3.306GluThr: 3.306 ± 0.086	4.472GluVal: 4.472 ± 0.101	0.685GluTrp: 0.685 ± 0.039	1.882GluTyr: 1.882 ± 0.059	0.0GluXaa: 0.0 ± 0.0
Phe	4.761PheAla: 4.761 ± 0.118	0.744PheCys: 0.744 ± 0.034	2.81PheAsp: 2.81 ± 0.067	2.606PheGlu: 2.606 ± 0.072	1.678PhePhe: 1.678 ± 0.051	3.741PheGly: 3.741 ± 0.098	0.587PheHis: 0.587 ± 0.031	1.656PheIle: 1.656 ± 0.058	1.389PheLys: 1.389 ± 0.053	3.453PheLeu: 3.453 ± 0.098	1.037PheMet: 1.037 ± 0.039	1.249PheAsn: 1.249 ± 0.046	1.479PhePro: 1.479 ± 0.052	0.915PheGln: 0.915 ± 0.047	1.577PheArg: 1.577 ± 0.04	2.526PheSer: 2.526 ± 0.07	2.142PheThr: 2.142 ± 0.063	3.418PheVal: 3.418 ± 0.09	0.555PheTrp: 0.555 ± 0.029	1.191PheTyr: 1.191 ± 0.044	0.0PheXaa: 0.0 ± 0.0
Gly	8.685GlyAla: 8.685 ± 0.134	1.584GlyCys: 1.584 ± 0.051	4.689GlyAsp: 4.689 ± 0.093	5.232GlyGlu: 5.232 ± 0.118	3.815GlyPhe: 3.815 ± 0.086	6.46GlyGly: 6.46 ± 0.137	1.435GlyHis: 1.435 ± 0.054	4.93GlyIle: 4.93 ± 0.098	4.139GlyLys: 4.139 ± 0.093	7.304GlyLeu: 7.304 ± 0.121	2.726GlyMet: 2.726 ± 0.076	2.389GlyAsn: 2.389 ± 0.081	2.321GlyPro: 2.321 ± 0.067	2.337GlyGln: 2.337 ± 0.067	4.917GlyArg: 4.917 ± 0.09	5.005GlySer: 5.005 ± 0.122	4.729GlyThr: 4.729 ± 0.113	6.555GlyVal: 6.555 ± 0.122	1.217GlyTrp: 1.217 ± 0.057	2.854GlyTyr: 2.854 ± 0.082	0.0GlyXaa: 0.0 ± 0.0
His	1.868HisAla: 1.868 ± 0.053	0.362HisCys: 0.362 ± 0.025	1.261HisAsp: 1.261 ± 0.047	1.283HisGlu: 1.283 ± 0.043	0.601HisPhe: 0.601 ± 0.031	1.587HisGly: 1.587 ± 0.055	0.382HisHis: 0.382 ± 0.035	0.821HisIle: 0.821 ± 0.036	0.525HisLys: 0.525 ± 0.03	1.587HisLeu: 1.587 ± 0.058	0.452HisMet: 0.452 ± 0.028	0.421HisAsn: 0.421 ± 0.027	1.183HisPro: 1.183 ± 0.049	0.387HisGln: 0.387 ± 0.024	1.118HisArg: 1.118 ± 0.039	0.844HisSer: 0.844 ± 0.04	0.8HisThr: 0.8 ± 0.044	1.469HisVal: 1.469 ± 0.057	0.235HisTrp: 0.235 ± 0.023	0.589HisTyr: 0.589 ± 0.034	0.0HisXaa: 0.0 ± 0.0
Ile	6.174IleAla: 6.174 ± 0.133	0.729IleCys: 0.729 ± 0.036	3.553IleAsp: 3.553 ± 0.079	3.673IleGlu: 3.673 ± 0.077	1.431IlePhe: 1.431 ± 0.049	4.113IleGly: 4.113 ± 0.086	0.711IleHis: 0.711 ± 0.035	2.321IleIle: 2.321 ± 0.075	1.81IleLys: 1.81 ± 0.05	3.738IleLeu: 3.738 ± 0.1	1.362IleMet: 1.362 ± 0.054	1.403IleAsn: 1.403 ± 0.06	2.306IlePro: 2.306 ± 0.073	1.032IleGln: 1.032 ± 0.047	2.401IleArg: 2.401 ± 0.059	2.492IleSer: 2.492 ± 0.067	2.567IleThr: 2.567 ± 0.074	4.761IleVal: 4.761 ± 0.103	0.503IleTrp: 0.503 ± 0.029	1.195IleTyr: 1.195 ± 0.05	0.0IleXaa: 0.0 ± 0.0
Lys	4.416LysAla: 4.416 ± 0.104	0.509LysCys: 0.509 ± 0.027	2.401LysAsp: 2.401 ± 0.079	2.597LysGlu: 2.597 ± 0.069	1.081LysPhe: 1.081 ± 0.038	3.139LysGly: 3.139 ± 0.085	0.717LysHis: 0.717 ± 0.042	1.795LysIle: 1.795 ± 0.063	2.193LysLys: 2.193 ± 0.079	3.535LysLeu: 3.535 ± 0.087	1.076LysMet: 1.076 ± 0.041	1.299LysAsn: 1.299 ± 0.049	1.876LysPro: 1.876 ± 0.058	1.338LysGln: 1.338 ± 0.052	2.9LysArg: 2.9 ± 0.083	2.255LysSer: 2.255 ± 0.059	2.376LysThr: 2.376 ± 0.063	2.8LysVal: 2.8 ± 0.072	0.445LysTrp: 0.445 ± 0.028	1.149LysTyr: 1.149 ± 0.043	0.0LysXaa: 0.0 ± 0.0
Leu	12.12LeuAla: 12.12 ± 0.18	1.57LeuCys: 1.57 ± 0.054	5.854LeuAsp: 5.854 ± 0.107	5.688LeuGlu: 5.688 ± 0.099	3.978LeuPhe: 3.978 ± 0.114	7.572LeuGly: 7.572 ± 0.147	1.589LeuHis: 1.589 ± 0.055	4.018LeuIle: 4.018 ± 0.104	3.377LeuLys: 3.377 ± 0.074	8.519LeuLeu: 8.519 ± 0.172	2.645LeuMet: 2.645 ± 0.068	2.252LeuAsn: 2.252 ± 0.064	4.548LeuPro: 4.548 ± 0.092	2.159LeuGln: 2.159 ± 0.054	5.2LeuArg: 5.2 ± 0.117	5.643LeuSer: 5.643 ± 0.098	4.43LeuThr: 4.43 ± 0.087	8.335LeuVal: 8.335 ± 0.143	0.939LeuTrp: 0.939 ± 0.038	2.543LeuTyr: 2.543 ± 0.068	0.0LeuXaa: 0.0 ± 0.0
Met	3.352MetAla: 3.352 ± 0.08	0.36MetCys: 0.36 ± 0.024	1.66MetAsp: 1.66 ± 0.052	1.706MetGlu: 1.706 ± 0.051	0.876MetPhe: 0.876 ± 0.042	2.335MetGly: 2.335 ± 0.067	0.455MetHis: 0.455 ± 0.029	1.249MetIle: 1.249 ± 0.048	1.193MetLys: 1.193 ± 0.045	2.597MetLeu: 2.597 ± 0.074	0.839MetMet: 0.839 ± 0.044	0.875MetAsn: 0.875 ± 0.039	1.423MetPro: 1.423 ± 0.048	0.853MetGln: 0.853 ± 0.038	1.831MetArg: 1.831 ± 0.055	1.739MetSer: 1.739 ± 0.059	1.562MetThr: 1.562 ± 0.056	1.885MetVal: 1.885 ± 0.06	0.269MetTrp: 0.269 ± 0.023	0.599MetTyr: 0.599 ± 0.031	0.0MetXaa: 0.0 ± 0.0
Asn	3.047AsnAla: 3.047 ± 0.082	0.426AsnCys: 0.426 ± 0.03	1.651AsnAsp: 1.651 ± 0.057	1.68AsnGlu: 1.68 ± 0.054	0.895AsnPhe: 0.895 ± 0.041	2.357AsnGly: 2.357 ± 0.073	0.535AsnHis: 0.535 ± 0.03	1.497AsnIle: 1.497 ± 0.056	1.024AsnLys: 1.024 ± 0.04	2.66AsnLeu: 2.66 ± 0.067	0.734AsnMet: 0.734 ± 0.039	0.81AsnAsn: 0.81 ± 0.042	2.002AsnPro: 2.002 ± 0.067	0.787AsnGln: 0.787 ± 0.041	1.685AsnArg: 1.685 ± 0.057	1.347AsnSer: 1.347 ± 0.056	1.426AsnThr: 1.426 ± 0.05	2.232AsnVal: 2.232 ± 0.071	0.349AsnTrp: 0.349 ± 0.023	0.861AsnTyr: 0.861 ± 0.047	0.0AsnXaa: 0.0 ± 0.0
Pro	5.049ProAla: 5.049 ± 0.097	0.601ProCys: 0.601 ± 0.031	3.149ProAsp: 3.149 ± 0.094	3.69ProGlu: 3.69 ± 0.092	1.895ProPhe: 1.895 ± 0.056	3.484ProGly: 3.484 ± 0.089	0.782ProHis: 0.782 ± 0.036	1.799ProIle: 1.799 ± 0.048	1.631ProLys: 1.631 ± 0.059	4.142ProLeu: 4.142 ± 0.077	1.014ProMet: 1.014 ± 0.04	1.247ProAsn: 1.247 ± 0.045	1.398ProPro: 1.398 ± 0.052	1.274ProGln: 1.274 ± 0.049	2.308ProArg: 2.308 ± 0.076	2.694ProSer: 2.694 ± 0.068	2.316ProThr: 2.316 ± 0.058	3.699ProVal: 3.699 ± 0.08	0.558ProTrp: 0.558 ± 0.034	1.572ProTyr: 1.572 ± 0.052	0.0ProXaa: 0.0 ± 0.0
Gln	3.496GlnAla: 3.496 ± 0.09	0.357GlnCys: 0.357 ± 0.031	1.384GlnAsp: 1.384 ± 0.044	1.795GlnGlu: 1.795 ± 0.06	0.953GlnPhe: 0.953 ± 0.041	2.315GlnGly: 2.315 ± 0.067	0.509GlnHis: 0.509 ± 0.03	1.431GlnIle: 1.431 ± 0.054	1.186GlnLys: 1.186 ± 0.044	2.472GlnLeu: 2.472 ± 0.068	0.882GlnMet: 0.882 ± 0.043	0.856GlnAsn: 0.856 ± 0.042	1.235GlnPro: 1.235 ± 0.048	1.079GlnGln: 1.079 ± 0.043	1.849GlnArg: 1.849 ± 0.066	1.428GlnSer: 1.428 ± 0.05	1.464GlnThr: 1.464 ± 0.055	2.11GlnVal: 2.11 ± 0.06	0.364GlnTrp: 0.364 ± 0.027	0.797GlnTyr: 0.797 ± 0.043	0.0GlnXaa: 0.0 ± 0.0
Arg	6.337ArgAla: 6.337 ± 0.129	0.988ArgCys: 0.988 ± 0.042	3.352ArgAsp: 3.352 ± 0.084	4.492ArgGlu: 4.492 ± 0.1	2.491ArgPhe: 2.491 ± 0.067	4.203ArgGly: 4.203 ± 0.08	1.1ArgHis: 1.1 ± 0.05	3.338ArgIle: 3.338 ± 0.085	2.79ArgLys: 2.79 ± 0.066	5.335ArgLeu: 5.335 ± 0.111	2.059ArgMet: 2.059 ± 0.059	1.768ArgAsn: 1.768 ± 0.055	2.328ArgPro: 2.328 ± 0.063	1.805ArgGln: 1.805 ± 0.056	4.303ArgArg: 4.303 ± 0.118	2.971ArgSer: 2.971 ± 0.079	3.142ArgThr: 3.142 ± 0.073	4.227ArgVal: 4.227 ± 0.101	0.712ArgTrp: 0.712 ± 0.033	2.069ArgTyr: 2.069 ± 0.062	0.0ArgXaa: 0.0 ± 0.0
Ser	5.661SerAla: 5.661 ± 0.122	0.914SerCys: 0.914 ± 0.043	3.051SerAsp: 3.051 ± 0.072	3.21SerGlu: 3.21 ± 0.079	2.645SerPhe: 2.645 ± 0.073	4.836SerGly: 4.836 ± 0.107	0.895SerHis: 0.895 ± 0.043	2.937SerIle: 2.937 ± 0.076	2.127SerLys: 2.127 ± 0.064	5.059SerLeu: 5.059 ± 0.102	1.526SerMet: 1.526 ± 0.05	1.543SerAsn: 1.543 ± 0.06	2.465SerPro: 2.465 ± 0.066	1.619SerGln: 1.619 ± 0.054	3.051SerArg: 3.051 ± 0.073	3.308SerSer: 3.308 ± 0.084	2.92SerThr: 2.92 ± 0.075	4.35SerVal: 4.35 ± 0.092	0.785SerTrp: 0.785 ± 0.037	1.915SerTyr: 1.915 ± 0.059	0.0SerXaa: 0.0 ± 0.0
Thr	5.277ThrAla: 5.277 ± 0.095	0.876ThrCys: 0.876 ± 0.041	2.851ThrAsp: 2.851 ± 0.084	2.67ThrGlu: 2.67 ± 0.078	2.044ThrPhe: 2.044 ± 0.073	4.704ThrGly: 4.704 ± 0.102	0.929ThrHis: 0.929 ± 0.04	2.585ThrIle: 2.585 ± 0.07	1.871ThrLys: 1.871 ± 0.063	4.829ThrLeu: 4.829 ± 0.097	1.343ThrMet: 1.343 ± 0.048	1.343ThrAsn: 1.343 ± 0.047	2.853ThrPro: 2.853 ± 0.085	1.289ThrGln: 1.289 ± 0.05	2.552ThrArg: 2.552 ± 0.063	2.793ThrSer: 2.793 ± 0.07	2.809ThrThr: 2.809 ± 0.082	4.797ThrVal: 4.797 ± 0.103	0.778ThrTrp: 0.778 ± 0.047	1.638ThrTyr: 1.638 ± 0.065	0.0ThrXaa: 0.0 ± 0.0
Val	9.194ValAla: 9.194 ± 0.17	1.364ValCys: 1.364 ± 0.053	5.056ValAsp: 5.056 ± 0.1	5.372ValGlu: 5.372 ± 0.1	3.365ValPhe: 3.365 ± 0.104	6.061ValGly: 6.061 ± 0.113	1.277ValHis: 1.277 ± 0.051	3.692ValIle: 3.692 ± 0.097	2.934ValLys: 2.934 ± 0.074	7.942ValLeu: 7.942 ± 0.148	2.051ValMet: 2.051 ± 0.068	2.232ValAsn: 2.232 ± 0.067	3.848ValPro: 3.848 ± 0.095	2.029ValGln: 2.029 ± 0.06	4.631ValArg: 4.631 ± 0.087	4.87ValSer: 4.87 ± 0.102	3.968ValThr: 3.968 ± 0.118	7.071ValVal: 7.071 ± 0.133	1.002ValTrp: 1.002 ± 0.039	2.354ValTyr: 2.354 ± 0.06	0.0ValXaa: 0.0 ± 0.0
Trp	1.142TrpAla: 1.142 ± 0.05	0.289TrpCys: 0.289 ± 0.024	0.824TrpAsp: 0.824 ± 0.033	0.822TrpGlu: 0.822 ± 0.041	0.525TrpPhe: 0.525 ± 0.029	1.09TrpGly: 1.09 ± 0.054	0.271TrpHis: 0.271 ± 0.017	0.641TrpIle: 0.641 ± 0.037	0.437TrpLys: 0.437 ± 0.027	1.255TrpLeu: 1.255 ± 0.051	0.393TrpMet: 0.393 ± 0.026	0.433TrpAsn: 0.433 ± 0.027	0.438TrpPro: 0.438 ± 0.029	0.421TrpGln: 0.421 ± 0.028	0.804TrpArg: 0.804 ± 0.032	0.692TrpSer: 0.692 ± 0.033	0.526TrpThr: 0.526 ± 0.033	0.839TrpVal: 0.839 ± 0.036	0.193TrpTrp: 0.193 ± 0.019	0.36TrpTyr: 0.36 ± 0.028	0.0TrpXaa: 0.0 ± 0.0
Tyr	3.149TyrAla: 3.149 ± 0.071	0.492TyrCys: 0.492 ± 0.025	2.277TyrAsp: 2.277 ± 0.063	2.074TyrGlu: 2.074 ± 0.059	1.186TyrPhe: 1.186 ± 0.042	2.761TyrGly: 2.761 ± 0.071	0.538TyrHis: 0.538 ± 0.032	1.069TyrIle: 1.069 ± 0.048	0.966TyrLys: 0.966 ± 0.044	3.179TyrLeu: 3.179 ± 0.072	0.64TyrMet: 0.64 ± 0.036	0.909TyrAsn: 0.909 ± 0.043	1.406TyrPro: 1.406 ± 0.054	0.978TyrGln: 0.978 ± 0.042	2.088TyrArg: 2.088 ± 0.071	1.398TyrSer: 1.398 ± 0.051	1.57TyrThr: 1.57 ± 0.064	2.249TyrVal: 2.249 ± 0.066	0.342TyrTrp: 0.342 ± 0.028	1.066TyrTyr: 1.066 ± 0.045	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 2027 proteins (591018 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

---