Amino acid dipepetide frequency for Anseongella ginsenosidimutans

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	8.456AlaAla: 8.456 ± 0.1	0.86AlaCys: 0.86 ± 0.026	4.261AlaAsp: 4.261 ± 0.064	5.397AlaGlu: 5.397 ± 0.073	3.892AlaPhe: 3.892 ± 0.058	8.173AlaGly: 8.173 ± 0.101	1.279AlaHis: 1.279 ± 0.034	5.008AlaIle: 5.008 ± 0.069	3.262AlaLys: 3.262 ± 0.051	7.964AlaLeu: 7.964 ± 0.099	1.714AlaMet: 1.714 ± 0.034	2.977AlaAsn: 2.977 ± 0.05	3.03AlaPro: 3.03 ± 0.058	2.429AlaGln: 2.429 ± 0.046	4.144AlaArg: 4.144 ± 0.059	5.091AlaSer: 5.091 ± 0.066	3.495AlaThr: 3.495 ± 0.059	5.314AlaVal: 5.314 ± 0.078	1.056AlaTrp: 1.056 ± 0.031	2.828AlaTyr: 2.828 ± 0.049	0.0AlaXaa: 0.0 ± 0.0
Cys	0.536CysAla: 0.536 ± 0.02	0.156CysCys: 0.156 ± 0.012	0.385CysAsp: 0.385 ± 0.019	0.463CysGlu: 0.463 ± 0.023	0.454CysPhe: 0.454 ± 0.021	0.678CysGly: 0.678 ± 0.027	0.226CysHis: 0.226 ± 0.014	0.568CysIle: 0.568 ± 0.02	0.35CysLys: 0.35 ± 0.017	0.884CysLeu: 0.884 ± 0.029	0.19CysMet: 0.19 ± 0.012	0.354CysAsn: 0.354 ± 0.016	0.363CysPro: 0.363 ± 0.018	0.252CysGln: 0.252 ± 0.014	0.492CysArg: 0.492 ± 0.021	0.585CysSer: 0.585 ± 0.021	0.417CysThr: 0.417 ± 0.018	0.422CysVal: 0.422 ± 0.018	0.107CysTrp: 0.107 ± 0.011	0.335CysTyr: 0.335 ± 0.018	0.0CysXaa: 0.0 ± 0.0
Asp	3.825AspAla: 3.825 ± 0.068	0.382AspCys: 0.382 ± 0.019	2.336AspAsp: 2.336 ± 0.049	3.445AspGlu: 3.445 ± 0.063	2.958AspPhe: 2.958 ± 0.049	3.887AspGly: 3.887 ± 0.067	1.13AspHis: 1.13 ± 0.032	3.708AspIle: 3.708 ± 0.052	2.959AspLys: 2.959 ± 0.043	5.026AspLeu: 5.026 ± 0.073	1.17AspMet: 1.17 ± 0.031	2.263AspAsn: 2.263 ± 0.049	2.827AspPro: 2.827 ± 0.053	1.679AspGln: 1.679 ± 0.035	2.663AspArg: 2.663 ± 0.042	2.87AspSer: 2.87 ± 0.056	2.567AspThr: 2.567 ± 0.048	3.066AspVal: 3.066 ± 0.048	0.848AspTrp: 0.848 ± 0.027	2.366AspTyr: 2.366 ± 0.047	0.0AspXaa: 0.0 ± 0.0
Glu	5.561GluAla: 5.561 ± 0.07	0.391GluCys: 0.391 ± 0.018	3.296GluAsp: 3.296 ± 0.058	5.462GluGlu: 5.462 ± 0.085	2.666GluPhe: 2.666 ± 0.052	4.835GluGly: 4.835 ± 0.058	1.197GluHis: 1.197 ± 0.032	4.459GluIle: 4.459 ± 0.058	5.335GluLys: 5.335 ± 0.095	6.612GluLeu: 6.612 ± 0.076	1.734GluMet: 1.734 ± 0.04	3.67GluAsn: 3.67 ± 0.059	2.235GluPro: 2.235 ± 0.043	2.8GluGln: 2.8 ± 0.048	3.505GluArg: 3.505 ± 0.057	3.386GluSer: 3.386 ± 0.046	3.484GluThr: 3.484 ± 0.049	4.225GluVal: 4.225 ± 0.067	0.803GluTrp: 0.803 ± 0.027	2.319GluTyr: 2.319 ± 0.044	0.0GluXaa: 0.0 ± 0.0
Phe	3.248PheAla: 3.248 ± 0.063	0.474PheCys: 0.474 ± 0.018	2.767PheAsp: 2.767 ± 0.05	2.838PheGlu: 2.838 ± 0.057	2.381PhePhe: 2.381 ± 0.05	3.465PheGly: 3.465 ± 0.058	0.969PheHis: 0.969 ± 0.028	3.107PheIle: 3.107 ± 0.053	2.181PheLys: 2.181 ± 0.043	4.71PheLeu: 4.71 ± 0.072	1.124PheMet: 1.124 ± 0.028	2.441PheAsn: 2.441 ± 0.047	2.063PhePro: 2.063 ± 0.039	1.453PheGln: 1.453 ± 0.032	2.877PheArg: 2.877 ± 0.056	3.831PheSer: 3.831 ± 0.052	2.736PheThr: 2.736 ± 0.049	2.506PheVal: 2.506 ± 0.049	0.637PheTrp: 0.637 ± 0.028	1.998PheTyr: 1.998 ± 0.036	0.0PheXaa: 0.0 ± 0.0
Gly	5.572GlyAla: 5.572 ± 0.085	0.673GlyCys: 0.673 ± 0.025	3.691GlyAsp: 3.691 ± 0.064	4.934GlyGlu: 4.934 ± 0.063	3.701GlyPhe: 3.701 ± 0.053	5.945GlyGly: 5.945 ± 0.112	1.378GlyHis: 1.378 ± 0.034	5.588GlyIle: 5.588 ± 0.079	5.322GlyLys: 5.322 ± 0.083	7.15GlyLeu: 7.15 ± 0.086	2.003GlyMet: 2.003 ± 0.039	3.854GlyAsn: 3.854 ± 0.081	2.387GlyPro: 2.387 ± 0.049	2.59GlyGln: 2.59 ± 0.05	3.88GlyArg: 3.88 ± 0.051	4.98GlySer: 4.98 ± 0.067	4.386GlyThr: 4.386 ± 0.075	4.562GlyVal: 4.562 ± 0.068	1.108GlyTrp: 1.108 ± 0.031	3.219GlyTyr: 3.219 ± 0.063	0.001GlyXaa: 0.001 ± 0.001
His	1.362HisAla: 1.362 ± 0.032	0.205HisCys: 0.205 ± 0.013	0.885HisAsp: 0.885 ± 0.026	1.092HisGlu: 1.092 ± 0.03	1.212HisPhe: 1.212 ± 0.033	1.269HisGly: 1.269 ± 0.033	0.5HisHis: 0.5 ± 0.021	1.331HisIle: 1.331 ± 0.035	0.838HisLys: 0.838 ± 0.03	1.975HisLeu: 1.975 ± 0.038	0.389HisMet: 0.389 ± 0.016	0.747HisAsn: 0.747 ± 0.023	1.237HisPro: 1.237 ± 0.037	0.695HisGln: 0.695 ± 0.021	1.053HisArg: 1.053 ± 0.032	1.147HisSer: 1.147 ± 0.031	1.014HisThr: 1.014 ± 0.031	1.048HisVal: 1.048 ± 0.033	0.313HisTrp: 0.313 ± 0.015	0.885HisTyr: 0.885 ± 0.03	0.0HisXaa: 0.0 ± 0.0
Ile	5.417IleAla: 5.417 ± 0.072	0.675IleCys: 0.675 ± 0.025	3.624IleAsp: 3.624 ± 0.054	3.82IleGlu: 3.82 ± 0.067	2.711IlePhe: 2.711 ± 0.055	4.418IleGly: 4.418 ± 0.06	1.297IleHis: 1.297 ± 0.027	4.032IleIle: 4.032 ± 0.069	3.157IleLys: 3.157 ± 0.056	5.868IleLeu: 5.868 ± 0.075	1.304IleMet: 1.304 ± 0.039	2.998IleAsn: 2.998 ± 0.052	3.133IlePro: 3.133 ± 0.047	1.873IleGln: 1.873 ± 0.037	3.997IleArg: 3.997 ± 0.058	4.727IleSer: 4.727 ± 0.065	3.791IleThr: 3.791 ± 0.067	3.661IleVal: 3.661 ± 0.062	0.719IleTrp: 0.719 ± 0.027	2.316IleTyr: 2.316 ± 0.041	0.0IleXaa: 0.0 ± 0.0
Lys	4.675LysAla: 4.675 ± 0.064	0.283LysCys: 0.283 ± 0.015	3.108LysAsp: 3.108 ± 0.057	4.489LysGlu: 4.489 ± 0.072	1.946LysPhe: 1.946 ± 0.037	4.159LysGly: 4.159 ± 0.06	0.995LysHis: 0.995 ± 0.03	3.648LysIle: 3.648 ± 0.052	4.106LysLys: 4.106 ± 0.077	4.891LysLeu: 4.891 ± 0.076	1.49LysMet: 1.49 ± 0.037	2.708LysAsn: 2.708 ± 0.046	2.268LysPro: 2.268 ± 0.047	2.059LysGln: 2.059 ± 0.043	2.69LysArg: 2.69 ± 0.047	2.88LysSer: 2.88 ± 0.051	3.054LysThr: 3.054 ± 0.047	3.529LysVal: 3.529 ± 0.057	0.715LysTrp: 0.715 ± 0.021	2.11LysTyr: 2.11 ± 0.045	0.0LysXaa: 0.0 ± 0.0
Leu	8.001LeuAla: 8.001 ± 0.086	0.85LeuCys: 0.85 ± 0.026	5.082LeuAsp: 5.082 ± 0.067	6.801LeuGlu: 6.801 ± 0.082	4.857LeuPhe: 4.857 ± 0.073	6.271LeuGly: 6.271 ± 0.077	1.842LeuHis: 1.842 ± 0.04	5.793LeuIle: 5.793 ± 0.076	6.0LeuLys: 6.0 ± 0.082	10.861LeuLeu: 10.861 ± 0.131	2.142LeuMet: 2.142 ± 0.044	4.645LeuAsn: 4.645 ± 0.072	4.895LeuPro: 4.895 ± 0.069	3.658LeuGln: 3.658 ± 0.057	5.007LeuArg: 5.007 ± 0.067	7.112LeuSer: 7.112 ± 0.074	4.967LeuThr: 4.967 ± 0.058	5.85LeuVal: 5.85 ± 0.074	0.992LeuTrp: 0.992 ± 0.031	3.423LeuTyr: 3.423 ± 0.047	0.0LeuXaa: 0.0 ± 0.0
Met	1.9MetAla: 1.9 ± 0.046	0.14MetCys: 0.14 ± 0.01	1.324MetAsp: 1.324 ± 0.031	1.667MetGlu: 1.667 ± 0.042	0.716MetPhe: 0.716 ± 0.025	1.636MetGly: 1.636 ± 0.041	0.469MetHis: 0.469 ± 0.019	1.413MetIle: 1.413 ± 0.033	1.794MetLys: 1.794 ± 0.034	2.199MetLeu: 2.199 ± 0.046	0.536MetMet: 0.536 ± 0.023	1.259MetAsn: 1.259 ± 0.033	1.094MetPro: 1.094 ± 0.027	1.025MetGln: 1.025 ± 0.027	1.136MetArg: 1.136 ± 0.029	1.198MetSer: 1.198 ± 0.031	1.105MetThr: 1.105 ± 0.034	1.376MetVal: 1.376 ± 0.033	0.197MetTrp: 0.197 ± 0.012	0.633MetTyr: 0.633 ± 0.022	0.0MetXaa: 0.0 ± 0.0
Asn	3.457AsnAla: 3.457 ± 0.062	0.349AsnCys: 0.349 ± 0.016	2.268AsnAsp: 2.268 ± 0.041	2.827AsnGlu: 2.827 ± 0.052	2.203AsnPhe: 2.203 ± 0.046	3.59AsnGly: 3.59 ± 0.063	0.777AsnHis: 0.777 ± 0.024	3.15AsnIle: 3.15 ± 0.054	2.399AsnLys: 2.399 ± 0.042	4.241AsnLeu: 4.241 ± 0.065	1.098AsnMet: 1.098 ± 0.029	2.248AsnAsn: 2.248 ± 0.064	2.568AsnPro: 2.568 ± 0.048	1.585AsnGln: 1.585 ± 0.036	2.439AsnArg: 2.439 ± 0.044	2.874AsnSer: 2.874 ± 0.065	2.55AsnThr: 2.55 ± 0.05	2.58AsnVal: 2.58 ± 0.042	0.672AsnTrp: 0.672 ± 0.022	2.124AsnTyr: 2.124 ± 0.057	0.0AsnXaa: 0.0 ± 0.0
Pro	4.53ProAla: 4.53 ± 0.072	0.269ProCys: 0.269 ± 0.014	3.018ProAsp: 3.018 ± 0.055	4.163ProGlu: 4.163 ± 0.062	2.037ProPhe: 2.037 ± 0.037	4.492ProGly: 4.492 ± 0.067	0.828ProHis: 0.828 ± 0.028	1.76ProIle: 1.76 ± 0.04	1.486ProLys: 1.486 ± 0.035	3.993ProLeu: 3.993 ± 0.054	0.79ProMet: 0.79 ± 0.022	1.522ProAsn: 1.522 ± 0.037	1.662ProPro: 1.662 ± 0.045	1.401ProGln: 1.401 ± 0.039	1.929ProArg: 1.929 ± 0.045	2.585ProSer: 2.585 ± 0.039	1.562ProThr: 1.562 ± 0.038	3.873ProVal: 3.873 ± 0.064	0.564ProTrp: 0.564 ± 0.021	1.63ProTyr: 1.63 ± 0.038	0.0ProXaa: 0.0 ± 0.0
Gln	3.031GlnAla: 3.031 ± 0.051	0.182GlnCys: 0.182 ± 0.012	1.633GlnAsp: 1.633 ± 0.037	2.578GlnGlu: 2.578 ± 0.053	1.461GlnPhe: 1.461 ± 0.039	2.457GlnGly: 2.457 ± 0.046	0.822GlnHis: 0.822 ± 0.023	1.767GlnIle: 1.767 ± 0.039	1.924GlnLys: 1.924 ± 0.041	3.919GlnLeu: 3.919 ± 0.059	0.815GlnMet: 0.815 ± 0.026	1.447GlnAsn: 1.447 ± 0.034	1.59GlnPro: 1.59 ± 0.034	1.779GlnGln: 1.779 ± 0.049	1.796GlnArg: 1.796 ± 0.033	1.806GlnSer: 1.806 ± 0.039	1.74GlnThr: 1.74 ± 0.036	2.416GlnVal: 2.416 ± 0.043	0.458GlnTrp: 0.458 ± 0.02	1.366GlnTyr: 1.366 ± 0.037	0.0GlnXaa: 0.0 ± 0.0
Arg	3.351ArgAla: 3.351 ± 0.045	0.317ArgCys: 0.317 ± 0.017	2.548ArgAsp: 2.548 ± 0.048	4.413ArgGlu: 4.413 ± 0.067	2.753ArgPhe: 2.753 ± 0.046	3.099ArgGly: 3.099 ± 0.05	1.012ArgHis: 1.012 ± 0.033	3.699ArgIle: 3.699 ± 0.054	3.512ArgLys: 3.512 ± 0.057	5.358ArgLeu: 5.358 ± 0.072	1.413ArgMet: 1.413 ± 0.034	2.635ArgAsn: 2.635 ± 0.048	2.124ArgPro: 2.124 ± 0.047	2.239ArgGln: 2.239 ± 0.043	2.73ArgArg: 2.73 ± 0.056	3.09ArgSer: 3.09 ± 0.047	2.313ArgThr: 2.313 ± 0.045	3.017ArgVal: 3.017 ± 0.049	0.725ArgTrp: 0.725 ± 0.024	2.366ArgTyr: 2.366 ± 0.041	0.0ArgXaa: 0.0 ± 0.0
Ser	5.036SerAla: 5.036 ± 0.062	0.642SerCys: 0.642 ± 0.02	3.016SerAsp: 3.016 ± 0.05	3.543SerGlu: 3.543 ± 0.047	3.377SerPhe: 3.377 ± 0.059	6.039SerGly: 6.039 ± 0.088	1.188SerHis: 1.188 ± 0.033	3.827SerIle: 3.827 ± 0.053	2.737SerLys: 2.737 ± 0.051	6.739SerLeu: 6.739 ± 0.079	1.406SerMet: 1.406 ± 0.038	2.585SerAsn: 2.585 ± 0.061	2.912SerPro: 2.912 ± 0.059	1.981SerGln: 1.981 ± 0.04	3.599SerArg: 3.599 ± 0.05	4.056SerSer: 4.056 ± 0.07	2.997SerThr: 2.997 ± 0.049	3.992SerVal: 3.992 ± 0.05	0.954SerTrp: 0.954 ± 0.027	2.6SerTyr: 2.6 ± 0.056	0.0SerXaa: 0.0 ± 0.0
Thr	4.684ThrAla: 4.684 ± 0.071	0.353ThrCys: 0.353 ± 0.018	2.806ThrAsp: 2.806 ± 0.057	3.012ThrGlu: 3.012 ± 0.05	2.452ThrPhe: 2.452 ± 0.056	5.223ThrGly: 5.223 ± 0.061	0.949ThrHis: 0.949 ± 0.023	3.434ThrIle: 3.434 ± 0.062	1.908ThrLys: 1.908 ± 0.043	4.94ThrLeu: 4.94 ± 0.066	0.954ThrMet: 0.954 ± 0.025	1.833ThrAsn: 1.833 ± 0.041	2.512ThrPro: 2.512 ± 0.045	1.368ThrGln: 1.368 ± 0.033	2.47ThrArg: 2.47 ± 0.045	3.141ThrSer: 3.141 ± 0.058	2.626ThrThr: 2.626 ± 0.055	3.616ThrVal: 3.616 ± 0.062	0.721ThrTrp: 0.721 ± 0.025	1.984ThrTyr: 1.984 ± 0.048	0.0ThrXaa: 0.0 ± 0.0
Val	4.384ValAla: 4.384 ± 0.061	0.564ValCys: 0.564 ± 0.02	2.929ValAsp: 2.929 ± 0.056	3.761ValGlu: 3.761 ± 0.061	3.277ValPhe: 3.277 ± 0.05	3.47ValGly: 3.47 ± 0.061	1.151ValHis: 1.151 ± 0.029	4.323ValIle: 4.323 ± 0.064	3.727ValLys: 3.727 ± 0.057	6.357ValLeu: 6.357 ± 0.074	1.384ValMet: 1.384 ± 0.035	3.271ValAsn: 3.271 ± 0.053	2.887ValPro: 2.887 ± 0.044	2.013ValGln: 2.013 ± 0.039	3.198ValArg: 3.198 ± 0.055	4.616ValSer: 4.616 ± 0.073	3.368ValThr: 3.368 ± 0.067	3.894ValVal: 3.894 ± 0.069	0.697ValTrp: 0.697 ± 0.026	2.423ValTyr: 2.423 ± 0.042	0.0ValXaa: 0.0 ± 0.0
Trp	0.864TrpAla: 0.864 ± 0.028	0.118TrpCys: 0.118 ± 0.01	0.724TrpAsp: 0.724 ± 0.025	0.923TrpGlu: 0.923 ± 0.031	0.61TrpPhe: 0.61 ± 0.021	0.928TrpGly: 0.928 ± 0.028	0.285TrpHis: 0.285 ± 0.016	0.77TrpIle: 0.77 ± 0.026	0.879TrpLys: 0.879 ± 0.026	1.385TrpLeu: 1.385 ± 0.036	0.392TrpMet: 0.392 ± 0.02	0.689TrpAsn: 0.689 ± 0.023	0.461TrpPro: 0.461 ± 0.02	0.552TrpGln: 0.552 ± 0.024	0.616TrpArg: 0.616 ± 0.023	0.662TrpSer: 0.662 ± 0.027	0.669TrpThr: 0.669 ± 0.025	0.735TrpVal: 0.735 ± 0.025	0.212TrpTrp: 0.212 ± 0.012	0.575TrpTyr: 0.575 ± 0.022	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.74TyrAla: 2.74 ± 0.045	0.336TyrCys: 0.336 ± 0.017	2.275TyrAsp: 2.275 ± 0.044	2.347TyrGlu: 2.347 ± 0.044	2.138TyrPhe: 2.138 ± 0.045	2.891TyrGly: 2.891 ± 0.047	0.903TyrHis: 0.903 ± 0.025	2.151TyrIle: 2.151 ± 0.039	1.929TyrLys: 1.929 ± 0.037	3.979TyrLeu: 3.979 ± 0.062	0.769TyrMet: 0.769 ± 0.026	1.853TyrAsn: 1.853 ± 0.049	1.842TyrPro: 1.842 ± 0.038	1.555TyrGln: 1.555 ± 0.036	2.492TyrArg: 2.492 ± 0.045	2.588TyrSer: 2.588 ± 0.046	2.146TyrThr: 2.146 ± 0.048	2.012TyrVal: 2.012 ± 0.041	0.553TyrTrp: 0.553 ± 0.02	1.816TyrTyr: 1.816 ± 0.043	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.001XaaGly: 0.001 ± 0.001	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.002XaaXaa: 0.002 ± 0.002

Statistics based on 3575 proteins (1307100 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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