Amino acid dipepetide frequency for secondary endosymbiont of Trabutina mannipara

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
5.072AlaAla: 5.072 ± 0.318
0.616AlaCys: 0.616 ± 0.086
3.377AlaAsp: 3.377 ± 0.259
3.929AlaGlu: 3.929 ± 0.294
1.887AlaPhe: 1.887 ± 0.168
4.276AlaGly: 4.276 ± 0.24
1.207AlaHis: 1.207 ± 0.135
6.227AlaIle: 6.227 ± 0.237
5.277AlaLys: 5.277 ± 0.292
6.831AlaLeu: 6.831 ± 0.36
1.656AlaMet: 1.656 ± 0.14
2.979AlaAsn: 2.979 ± 0.231
1.887AlaPro: 1.887 ± 0.167
2.221AlaGln: 2.221 ± 0.15
3.723AlaArg: 3.723 ± 0.24
3.146AlaSer: 3.146 ± 0.207
3.171AlaThr: 3.171 ± 0.248
4.378AlaVal: 4.378 ± 0.258
0.462AlaTrp: 0.462 ± 0.074
1.926AlaTyr: 1.926 ± 0.19
0.0AlaXaa: 0.0 ± 0.0
Cys
0.732CysAla: 0.732 ± 0.09
0.167CysCys: 0.167 ± 0.047
0.539CysAsp: 0.539 ± 0.086
0.578CysGlu: 0.578 ± 0.077
0.449CysPhe: 0.449 ± 0.071
1.156CysGly: 1.156 ± 0.124
0.385CysHis: 0.385 ± 0.066
1.014CysIle: 1.014 ± 0.125
0.835CysLys: 0.835 ± 0.115
0.95CysLeu: 0.95 ± 0.112
0.218CysMet: 0.218 ± 0.05
0.745CysAsn: 0.745 ± 0.11
0.462CysPro: 0.462 ± 0.085
0.462CysGln: 0.462 ± 0.083
0.693CysArg: 0.693 ± 0.094
0.886CysSer: 0.886 ± 0.108
0.68CysThr: 0.68 ± 0.098
0.488CysVal: 0.488 ± 0.077
0.141CysTrp: 0.141 ± 0.047
0.501CysTyr: 0.501 ± 0.1
0.0CysXaa: 0.0 ± 0.0
Asp
3.159AspAla: 3.159 ± 0.225
0.449AspCys: 0.449 ± 0.071
1.964AspAsp: 1.964 ± 0.159
2.362AspGlu: 2.362 ± 0.198
2.491AspPhe: 2.491 ± 0.18
2.529AspGly: 2.529 ± 0.226
0.847AspHis: 0.847 ± 0.122
5.919AspIle: 5.919 ± 0.3
3.89AspLys: 3.89 ± 0.225
4.763AspLeu: 4.763 ± 0.304
1.207AspMet: 1.207 ± 0.135
3.287AspAsn: 3.287 ± 0.222
1.746AspPro: 1.746 ± 0.131
1.515AspGln: 1.515 ± 0.155
2.645AspArg: 2.645 ± 0.197
2.722AspSer: 2.722 ± 0.178
2.247AspThr: 2.247 ± 0.172
2.863AspVal: 2.863 ± 0.245
0.411AspTrp: 0.411 ± 0.064
1.913AspTyr: 1.913 ± 0.145
0.0AspXaa: 0.0 ± 0.0
Glu
3.788GluAla: 3.788 ± 0.264
0.603GluCys: 0.603 ± 0.089
2.658GluAsp: 2.658 ± 0.226
3.582GluGlu: 3.582 ± 0.266
2.093GluPhe: 2.093 ± 0.186
2.979GluGly: 2.979 ± 0.21
1.541GluHis: 1.541 ± 0.13
6.304GluIle: 6.304 ± 0.317
5.046GluLys: 5.046 ± 0.259
5.418GluLeu: 5.418 ± 0.284
1.361GluMet: 1.361 ± 0.149
3.236GluAsn: 3.236 ± 0.225
1.438GluPro: 1.438 ± 0.143
2.529GluGln: 2.529 ± 0.18
3.569GluArg: 3.569 ± 0.213
3.03GluSer: 3.03 ± 0.188
2.465GluThr: 2.465 ± 0.202
4.096GluVal: 4.096 ± 0.266
0.424GluTrp: 0.424 ± 0.077
2.106GluTyr: 2.106 ± 0.159
0.0GluXaa: 0.0 ± 0.0
Phe
2.08PheAla: 2.08 ± 0.159
0.706PheCys: 0.706 ± 0.081
2.337PheAsp: 2.337 ± 0.187
2.144PheGlu: 2.144 ± 0.161
2.067PhePhe: 2.067 ± 0.181
2.298PheGly: 2.298 ± 0.18
0.745PheHis: 0.745 ± 0.092
4.032PheIle: 4.032 ± 0.279
2.388PheLys: 2.388 ± 0.189
3.48PheLeu: 3.48 ± 0.258
1.13PheMet: 1.13 ± 0.13
2.645PheAsn: 2.645 ± 0.189
1.361PhePro: 1.361 ± 0.155
1.233PheGln: 1.233 ± 0.122
1.798PheArg: 1.798 ± 0.149
3.197PheSer: 3.197 ± 0.179
2.029PheThr: 2.029 ± 0.182
1.836PheVal: 1.836 ± 0.16
0.36PheTrp: 0.36 ± 0.07
1.785PheTyr: 1.785 ± 0.151
0.0PheXaa: 0.0 ± 0.0
Gly
3.518GlyAla: 3.518 ± 0.259
0.809GlyCys: 0.809 ± 0.115
2.85GlyAsp: 2.85 ± 0.197
3.364GlyGlu: 3.364 ± 0.269
2.619GlyPhe: 2.619 ± 0.193
3.852GlyGly: 3.852 ± 0.297
1.515GlyHis: 1.515 ± 0.129
7.062GlyIle: 7.062 ± 0.284
5.2GlyLys: 5.2 ± 0.33
5.149GlyLeu: 5.149 ± 0.228
1.412GlyMet: 1.412 ± 0.13
3.325GlyAsn: 3.325 ± 0.257
1.849GlyPro: 1.849 ± 0.158
2.029GlyGln: 2.029 ± 0.192
3.801GlyArg: 3.801 ± 0.251
3.531GlySer: 3.531 ± 0.205
3.351GlyThr: 3.351 ± 0.171
3.685GlyVal: 3.685 ± 0.234
0.719GlyTrp: 0.719 ± 0.119
2.247GlyTyr: 2.247 ± 0.178
0.0GlyXaa: 0.0 ± 0.0
His
1.22HisAla: 1.22 ± 0.128
0.282HisCys: 0.282 ± 0.056
0.835HisAsp: 0.835 ± 0.116
1.027HisGlu: 1.027 ± 0.119
0.899HisPhe: 0.899 ± 0.122
1.464HisGly: 1.464 ± 0.141
0.68HisHis: 0.68 ± 0.095
2.221HisIle: 2.221 ± 0.159
1.721HisLys: 1.721 ± 0.174
2.054HisLeu: 2.054 ± 0.149
0.488HisMet: 0.488 ± 0.074
1.643HisAsn: 1.643 ± 0.156
1.194HisPro: 1.194 ± 0.134
0.899HisGln: 0.899 ± 0.105
1.13HisArg: 1.13 ± 0.116
1.194HisSer: 1.194 ± 0.145
1.194HisThr: 1.194 ± 0.121
1.091HisVal: 1.091 ± 0.132
0.205HisTrp: 0.205 ± 0.05
0.835HisTyr: 0.835 ± 0.093
0.0HisXaa: 0.0 ± 0.0
Ile
7.447IleAla: 7.447 ± 0.328
1.348IleCys: 1.348 ± 0.139
5.688IleAsp: 5.688 ± 0.297
6.869IleGlu: 6.869 ± 0.281
3.39IlePhe: 3.39 ± 0.243
6.51IleGly: 6.51 ± 0.313
1.952IleHis: 1.952 ± 0.142
9.129IleIle: 9.129 ± 0.41
7.601IleLys: 7.601 ± 0.323
8.641IleLeu: 8.641 ± 0.357
2.221IleMet: 2.221 ± 0.184
6.728IleAsn: 6.728 ± 0.319
3.171IlePro: 3.171 ± 0.19
2.529IleGln: 2.529 ± 0.171
5.136IleArg: 5.136 ± 0.239
6.163IleSer: 6.163 ± 0.288
5.611IleThr: 5.611 ± 0.268
5.56IleVal: 5.56 ± 0.312
0.745IleTrp: 0.745 ± 0.098
2.889IleTyr: 2.889 ± 0.195
0.0IleXaa: 0.0 ± 0.0
Lys
4.25LysAla: 4.25 ± 0.271
0.732LysCys: 0.732 ± 0.094
2.979LysAsp: 2.979 ± 0.253
4.815LysGlu: 4.815 ± 0.225
2.94LysPhe: 2.94 ± 0.201
4.083LysGly: 4.083 ± 0.244
1.374LysHis: 1.374 ± 0.14
8.448LysIle: 8.448 ± 0.439
7.652LysLys: 7.652 ± 0.411
7.588LysLeu: 7.588 ± 0.339
2.17LysMet: 2.17 ± 0.152
5.868LysAsn: 5.868 ± 0.307
1.9LysPro: 1.9 ± 0.159
2.568LysGln: 2.568 ± 0.178
4.199LysArg: 4.199 ± 0.271
4.173LysSer: 4.173 ± 0.211
3.159LysThr: 3.159 ± 0.225
4.404LysVal: 4.404 ± 0.221
0.449LysTrp: 0.449 ± 0.062
2.478LysTyr: 2.478 ± 0.2
0.0LysXaa: 0.0 ± 0.0
Leu
6.921LeuAla: 6.921 ± 0.32
1.079LeuCys: 1.079 ± 0.116
5.264LeuAsp: 5.264 ± 0.235
6.073LeuGlu: 6.073 ± 0.255
3.775LeuPhe: 3.775 ± 0.206
5.316LeuGly: 5.316 ± 0.259
2.709LeuHis: 2.709 ± 0.179
7.999LeuIle: 7.999 ± 0.325
6.381LeuLys: 6.381 ± 0.314
10.143LeuLeu: 10.143 ± 0.461
1.964LeuMet: 1.964 ± 0.185
5.778LeuAsn: 5.778 ± 0.218
4.057LeuPro: 4.057 ± 0.238
4.07LeuGln: 4.07 ± 0.249
5.932LeuArg: 5.932 ± 0.313
5.932LeuSer: 5.932 ± 0.279
5.072LeuThr: 5.072 ± 0.277
5.97LeuVal: 5.97 ± 0.262
0.835LeuTrp: 0.835 ± 0.114
2.902LeuTyr: 2.902 ± 0.217
0.0LeuXaa: 0.0 ± 0.0
Met
1.656MetAla: 1.656 ± 0.145
0.154MetCys: 0.154 ± 0.039
1.079MetAsp: 1.079 ± 0.115
1.271MetGlu: 1.271 ± 0.129
0.937MetPhe: 0.937 ± 0.112
1.425MetGly: 1.425 ± 0.14
0.68MetHis: 0.68 ± 0.096
1.939MetIle: 1.939 ± 0.171
1.592MetLys: 1.592 ± 0.122
2.761MetLeu: 2.761 ± 0.178
0.655MetMet: 0.655 ± 0.117
1.348MetAsn: 1.348 ± 0.142
0.95MetPro: 0.95 ± 0.119
1.258MetGln: 1.258 ± 0.121
1.541MetArg: 1.541 ± 0.135
1.335MetSer: 1.335 ± 0.133
1.104MetThr: 1.104 ± 0.129
1.618MetVal: 1.618 ± 0.161
0.103MetTrp: 0.103 ± 0.036
0.655MetTyr: 0.655 ± 0.081
0.0MetXaa: 0.0 ± 0.0
Asn
3.351AsnAla: 3.351 ± 0.222
0.847AsnCys: 0.847 ± 0.093
2.812AsnAsp: 2.812 ± 0.165
2.838AsnGlu: 2.838 ± 0.199
2.555AsnPhe: 2.555 ± 0.174
3.646AsnGly: 3.646 ± 0.221
1.13AsnHis: 1.13 ± 0.139
7.049AsnIle: 7.049 ± 0.372
5.611AsnLys: 5.611 ± 0.286
5.56AsnLeu: 5.56 ± 0.282
1.733AsnMet: 1.733 ± 0.149
4.16AsnAsn: 4.16 ± 0.25
1.939AsnPro: 1.939 ± 0.154
1.913AsnGln: 1.913 ± 0.116
2.645AsnArg: 2.645 ± 0.2
3.261AsnSer: 3.261 ± 0.241
2.889AsnThr: 2.889 ± 0.201
2.953AsnVal: 2.953 ± 0.195
0.591AsnTrp: 0.591 ± 0.091
2.632AsnTyr: 2.632 ± 0.184
0.0AsnXaa: 0.0 ± 0.0
Pro
1.862ProAla: 1.862 ± 0.155
0.321ProCys: 0.321 ± 0.057
1.502ProAsp: 1.502 ± 0.148
2.35ProGlu: 2.35 ± 0.197
1.425ProPhe: 1.425 ± 0.152
2.298ProGly: 2.298 ± 0.187
0.745ProHis: 0.745 ± 0.104
3.236ProIle: 3.236 ± 0.181
2.273ProLys: 2.273 ± 0.156
3.21ProLeu: 3.21 ± 0.206
0.822ProMet: 0.822 ± 0.099
1.862ProAsn: 1.862 ± 0.152
0.822ProPro: 0.822 ± 0.109
1.22ProGln: 1.22 ± 0.144
1.143ProArg: 1.143 ± 0.128
1.875ProSer: 1.875 ± 0.135
1.759ProThr: 1.759 ± 0.127
2.414ProVal: 2.414 ± 0.192
0.27ProTrp: 0.27 ± 0.057
1.412ProTyr: 1.412 ± 0.129
0.0ProXaa: 0.0 ± 0.0
Gln
2.44GlnAla: 2.44 ± 0.188
0.385GlnCys: 0.385 ± 0.069
1.322GlnAsp: 1.322 ± 0.124
1.952GlnGlu: 1.952 ± 0.167
1.31GlnPhe: 1.31 ± 0.117
1.964GlnGly: 1.964 ± 0.168
1.22GlnHis: 1.22 ± 0.134
3.236GlnIle: 3.236 ± 0.202
2.517GlnLys: 2.517 ± 0.216
4.263GlnLeu: 4.263 ± 0.284
0.796GlnMet: 0.796 ± 0.1
1.759GlnAsn: 1.759 ± 0.152
1.079GlnPro: 1.079 ± 0.121
1.99GlnGln: 1.99 ± 0.154
2.029GlnArg: 2.029 ± 0.175
1.81GlnSer: 1.81 ± 0.13
1.387GlnThr: 1.387 ± 0.137
2.606GlnVal: 2.606 ± 0.171
0.449GlnTrp: 0.449 ± 0.085
1.387GlnTyr: 1.387 ± 0.126
0.0GlnXaa: 0.0 ± 0.0
Arg
3.313ArgAla: 3.313 ± 0.226
0.68ArgCys: 0.68 ± 0.087
2.414ArgAsp: 2.414 ± 0.206
2.979ArgGlu: 2.979 ± 0.198
2.427ArgPhe: 2.427 ± 0.147
3.48ArgGly: 3.48 ± 0.191
1.104ArgHis: 1.104 ± 0.138
5.675ArgIle: 5.675 ± 0.292
3.993ArgLys: 3.993 ± 0.262
5.162ArgLeu: 5.162 ± 0.293
1.284ArgMet: 1.284 ± 0.122
3.146ArgAsn: 3.146 ± 0.193
1.656ArgPro: 1.656 ± 0.146
2.157ArgGln: 2.157 ± 0.201
3.441ArgArg: 3.441 ± 0.24
3.313ArgSer: 3.313 ± 0.237
2.812ArgThr: 2.812 ± 0.173
3.197ArgVal: 3.197 ± 0.219
0.642ArgTrp: 0.642 ± 0.106
2.054ArgTyr: 2.054 ± 0.166
0.0ArgXaa: 0.0 ± 0.0
Ser
3.775SerAla: 3.775 ± 0.205
0.616SerCys: 0.616 ± 0.082
2.773SerAsp: 2.773 ± 0.188
3.223SerGlu: 3.223 ± 0.216
2.311SerPhe: 2.311 ± 0.162
4.481SerGly: 4.481 ± 0.258
0.95SerHis: 0.95 ± 0.11
5.958SerIle: 5.958 ± 0.259
4.276SerLys: 4.276 ± 0.227
5.842SerLeu: 5.842 ± 0.275
1.322SerMet: 1.322 ± 0.125
3.223SerAsn: 3.223 ± 0.194
1.682SerPro: 1.682 ± 0.131
1.823SerGln: 1.823 ± 0.164
3.184SerArg: 3.184 ± 0.193
3.634SerSer: 3.634 ± 0.25
3.146SerThr: 3.146 ± 0.205
3.236SerVal: 3.236 ± 0.179
0.616SerTrp: 0.616 ± 0.085
2.029SerTyr: 2.029 ± 0.167
0.0SerXaa: 0.0 ± 0.0
Thr
3.634ThrAla: 3.634 ± 0.233
0.758ThrCys: 0.758 ± 0.121
2.658ThrAsp: 2.658 ± 0.197
2.992ThrGlu: 2.992 ± 0.212
1.887ThrPhe: 1.887 ± 0.132
3.852ThrGly: 3.852 ± 0.206
0.963ThrHis: 0.963 ± 0.112
4.674ThrIle: 4.674 ± 0.285
3.248ThrLys: 3.248 ± 0.211
5.932ThrLeu: 5.932 ± 0.324
1.194ThrMet: 1.194 ± 0.117
2.491ThrAsn: 2.491 ± 0.172
1.887ThrPro: 1.887 ± 0.166
1.489ThrGln: 1.489 ± 0.136
2.247ThrArg: 2.247 ± 0.175
2.838ThrSer: 2.838 ± 0.187
2.709ThrThr: 2.709 ± 0.201
3.133ThrVal: 3.133 ± 0.261
0.308ThrTrp: 0.308 ± 0.063
1.194ThrTyr: 1.194 ± 0.15
0.0ThrXaa: 0.0 ± 0.0
Val
3.749ValAla: 3.749 ± 0.284
0.732ValCys: 0.732 ± 0.106
3.582ValAsp: 3.582 ± 0.231
3.762ValGlu: 3.762 ± 0.244
2.067ValPhe: 2.067 ± 0.186
3.505ValGly: 3.505 ± 0.227
1.4ValHis: 1.4 ± 0.144
5.585ValIle: 5.585 ± 0.243
4.378ValLys: 4.378 ± 0.281
5.585ValLeu: 5.585 ± 0.278
1.374ValMet: 1.374 ± 0.132
3.402ValAsn: 3.402 ± 0.183
2.375ValPro: 2.375 ± 0.138
1.836ValGln: 1.836 ± 0.135
3.415ValArg: 3.415 ± 0.221
3.634ValSer: 3.634 ± 0.2
3.544ValThr: 3.544 ± 0.218
4.16ValVal: 4.16 ± 0.285
0.437ValTrp: 0.437 ± 0.086
1.489ValTyr: 1.489 ± 0.13
0.0ValXaa: 0.0 ± 0.0
Trp
0.321TrpAla: 0.321 ± 0.066
0.116TrpCys: 0.116 ± 0.045
0.437TrpAsp: 0.437 ± 0.084
0.334TrpGlu: 0.334 ± 0.068
0.501TrpPhe: 0.501 ± 0.085
0.321TrpGly: 0.321 ± 0.052
0.205TrpHis: 0.205 ± 0.049
0.847TrpIle: 0.847 ± 0.114
0.578TrpLys: 0.578 ± 0.093
1.079TrpLeu: 1.079 ± 0.131
0.282TrpMet: 0.282 ± 0.058
0.424TrpAsn: 0.424 ± 0.08
0.321TrpPro: 0.321 ± 0.062
0.578TrpGln: 0.578 ± 0.089
0.526TrpArg: 0.526 ± 0.089
0.475TrpSer: 0.475 ± 0.073
0.308TrpThr: 0.308 ± 0.068
0.578TrpVal: 0.578 ± 0.096
0.09TrpTrp: 0.09 ± 0.034
0.347TrpTyr: 0.347 ± 0.069
0.0TrpXaa: 0.0 ± 0.0
Tyr
1.964TyrAla: 1.964 ± 0.157
0.68TyrCys: 0.68 ± 0.086
1.862TyrAsp: 1.862 ± 0.161
1.823TyrGlu: 1.823 ± 0.137
1.618TyrPhe: 1.618 ± 0.168
2.452TyrGly: 2.452 ± 0.158
0.924TyrHis: 0.924 ± 0.106
2.773TyrIle: 2.773 ± 0.202
1.772TyrLys: 1.772 ± 0.144
3.762TyrLeu: 3.762 ± 0.188
0.758TyrMet: 0.758 ± 0.105
2.067TyrAsn: 2.067 ± 0.18
1.04TyrPro: 1.04 ± 0.118
1.579TyrGln: 1.579 ± 0.165
2.131TyrArg: 2.131 ± 0.174
1.952TyrSer: 1.952 ± 0.17
1.451TyrThr: 1.451 ± 0.16
1.759TyrVal: 1.759 ± 0.141
0.411TyrTrp: 0.411 ± 0.086
1.464TyrTyr: 1.464 ± 0.154
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 237 proteins (77885 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski