Amino acid dipepetide frequency for Photorhabdus temperata subsp. temperata M1021

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	7.428AlaAla: 7.428 ± 0.115	1.033AlaCys: 1.033 ± 0.033	4.233AlaAsp: 4.233 ± 0.062	5.283AlaGlu: 5.283 ± 0.078	3.225AlaPhe: 3.225 ± 0.057	6.25AlaGly: 6.25 ± 0.08	1.657AlaHis: 1.657 ± 0.038	5.628AlaIle: 5.628 ± 0.088	3.994AlaLys: 3.994 ± 0.072	9.631AlaLeu: 9.631 ± 0.123	2.258AlaMet: 2.258 ± 0.048	3.212AlaAsn: 3.212 ± 0.063	2.858AlaPro: 2.858 ± 0.062	3.542AlaGln: 3.542 ± 0.062	4.203AlaArg: 4.203 ± 0.068	4.515AlaSer: 4.515 ± 0.067	3.956AlaThr: 3.956 ± 0.063	5.705AlaVal: 5.705 ± 0.086	1.002AlaTrp: 1.002 ± 0.028	2.454AlaTyr: 2.454 ± 0.05	0.001AlaXaa: 0.001 ± 0.001
Cys	0.848CysAla: 0.848 ± 0.026	0.24CysCys: 0.24 ± 0.018	0.652CysAsp: 0.652 ± 0.024	0.599CysGlu: 0.599 ± 0.024	0.52CysPhe: 0.52 ± 0.02	1.061CysGly: 1.061 ± 0.033	0.393CysHis: 0.393 ± 0.019	0.76CysIle: 0.76 ± 0.027	0.457CysLys: 0.457 ± 0.022	1.171CysLeu: 1.171 ± 0.033	0.236CysMet: 0.236 ± 0.014	0.417CysAsn: 0.417 ± 0.018	0.515CysPro: 0.515 ± 0.022	0.598CysGln: 0.598 ± 0.023	0.715CysArg: 0.715 ± 0.032	0.783CysSer: 0.783 ± 0.03	0.502CysThr: 0.502 ± 0.021	0.674CysVal: 0.674 ± 0.024	0.229CysTrp: 0.229 ± 0.015	0.445CysTyr: 0.445 ± 0.021	0.001CysXaa: 0.001 ± 0.001
Asp	4.135AspAla: 4.135 ± 0.055	0.592AspCys: 0.592 ± 0.023	2.739AspAsp: 2.739 ± 0.053	3.535AspGlu: 3.535 ± 0.057	2.276AspPhe: 2.276 ± 0.041	3.639AspGly: 3.639 ± 0.061	1.043AspHis: 1.043 ± 0.026	4.275AspIle: 4.275 ± 0.062	3.03AspLys: 3.03 ± 0.062	4.784AspLeu: 4.784 ± 0.071	1.301AspMet: 1.301 ± 0.034	2.732AspAsn: 2.732 ± 0.052	2.151AspPro: 2.151 ± 0.055	1.731AspGln: 1.731 ± 0.045	2.565AspArg: 2.565 ± 0.049	3.033AspSer: 3.033 ± 0.055	2.51AspThr: 2.51 ± 0.048	3.278AspVal: 3.278 ± 0.058	0.831AspTrp: 0.831 ± 0.028	2.072AspTyr: 2.072 ± 0.047	0.0AspXaa: 0.0 ± 0.0
Glu	4.498GluAla: 4.498 ± 0.074	0.547GluCys: 0.547 ± 0.024	2.431GluAsp: 2.431 ± 0.051	3.644GluGlu: 3.644 ± 0.055	2.092GluPhe: 2.092 ± 0.042	3.372GluGly: 3.372 ± 0.057	1.629GluHis: 1.629 ± 0.043	4.221GluIle: 4.221 ± 0.066	3.885GluLys: 3.885 ± 0.058	6.581GluLeu: 6.581 ± 0.089	1.657GluMet: 1.657 ± 0.042	2.969GluAsn: 2.969 ± 0.054	2.073GluPro: 2.073 ± 0.043	3.887GluGln: 3.887 ± 0.07	3.706GluArg: 3.706 ± 0.068	3.302GluSer: 3.302 ± 0.059	3.08GluThr: 3.08 ± 0.055	3.542GluVal: 3.542 ± 0.066	0.791GluTrp: 0.791 ± 0.028	1.796GluTyr: 1.796 ± 0.043	0.0GluXaa: 0.0 ± 0.0
Phe	3.083PheAla: 3.083 ± 0.063	0.592PheCys: 0.592 ± 0.025	2.505PheAsp: 2.505 ± 0.047	1.981PheGlu: 1.981 ± 0.044	1.685PhePhe: 1.685 ± 0.051	2.848PheGly: 2.848 ± 0.053	0.852PheHis: 0.852 ± 0.028	2.965PheIle: 2.965 ± 0.054	1.647PheLys: 1.647 ± 0.031	3.225PheLeu: 3.225 ± 0.062	0.958PheMet: 0.958 ± 0.031	2.049PheAsn: 2.049 ± 0.045	1.569PhePro: 1.569 ± 0.038	1.259PheGln: 1.259 ± 0.037	1.796PheArg: 1.796 ± 0.036	3.288PheSer: 3.288 ± 0.055	2.272PheThr: 2.272 ± 0.05	2.303PheVal: 2.303 ± 0.046	0.584PheTrp: 0.584 ± 0.022	1.306PheTyr: 1.306 ± 0.032	0.001PheXaa: 0.001 ± 0.001
Gly	5.09GlyAla: 5.09 ± 0.087	0.996GlyCys: 0.996 ± 0.031	3.504GlyAsp: 3.504 ± 0.068	4.272GlyGlu: 4.272 ± 0.069	2.959GlyPhe: 2.959 ± 0.05	5.028GlyGly: 5.028 ± 0.085	1.596GlyHis: 1.596 ± 0.042	5.104GlyIle: 5.104 ± 0.073	4.23GlyLys: 4.23 ± 0.067	6.772GlyLeu: 6.772 ± 0.089	1.976GlyMet: 1.976 ± 0.045	2.976GlyAsn: 2.976 ± 0.066	1.723GlyPro: 1.723 ± 0.043	3.001GlyGln: 3.001 ± 0.058	3.627GlyArg: 3.627 ± 0.06	4.05GlySer: 4.05 ± 0.072	3.344GlyThr: 3.344 ± 0.06	4.977GlyVal: 4.977 ± 0.07	1.111GlyTrp: 1.111 ± 0.03	2.71GlyTyr: 2.71 ± 0.043	0.001GlyXaa: 0.001 ± 0.001
His	1.534HisAla: 1.534 ± 0.04	0.389HisCys: 0.389 ± 0.02	1.182HisAsp: 1.182 ± 0.032	1.149HisGlu: 1.149 ± 0.028	1.02HisPhe: 1.02 ± 0.03	1.575HisGly: 1.575 ± 0.043	0.88HisHis: 0.88 ± 0.03	1.616HisIle: 1.616 ± 0.036	0.949HisLys: 0.949 ± 0.034	2.442HisLeu: 2.442 ± 0.047	0.549HisMet: 0.549 ± 0.023	0.973HisAsn: 0.973 ± 0.03	1.252HisPro: 1.252 ± 0.036	1.391HisGln: 1.391 ± 0.038	1.301HisArg: 1.301 ± 0.036	1.439HisSer: 1.439 ± 0.037	1.15HisThr: 1.15 ± 0.033	1.193HisVal: 1.193 ± 0.035	0.424HisTrp: 0.424 ± 0.019	0.997HisTyr: 0.997 ± 0.031	0.0HisXaa: 0.0 ± 0.0
Ile	6.001IleAla: 6.001 ± 0.083	0.842IleCys: 0.842 ± 0.026	3.98IleAsp: 3.98 ± 0.069	4.296IleGlu: 4.296 ± 0.061	2.322IlePhe: 2.322 ± 0.051	4.729IleGly: 4.729 ± 0.076	1.411IleHis: 1.411 ± 0.034	4.265IleIle: 4.265 ± 0.084	3.359IleLys: 3.359 ± 0.075	5.825IleLeu: 5.825 ± 0.083	1.419IleMet: 1.419 ± 0.039	3.568IleAsn: 3.568 ± 0.063	3.134IlePro: 3.134 ± 0.059	2.426IleGln: 2.426 ± 0.053	3.363IleArg: 3.363 ± 0.052	4.929IleSer: 4.929 ± 0.062	4.105IleThr: 4.105 ± 0.059	3.918IleVal: 3.918 ± 0.064	0.812IleTrp: 0.812 ± 0.027	2.082IleTyr: 2.082 ± 0.05	0.002IleXaa: 0.002 ± 0.001
Lys	4.149LysAla: 4.149 ± 0.078	0.358LysCys: 0.358 ± 0.017	2.489LysAsp: 2.489 ± 0.06	3.194LysGlu: 3.194 ± 0.058	1.453LysPhe: 1.453 ± 0.04	3.276LysGly: 3.276 ± 0.054	1.055LysHis: 1.055 ± 0.03	3.381LysIle: 3.381 ± 0.063	2.901LysLys: 2.901 ± 0.056	5.141LysLeu: 5.141 ± 0.082	1.395LysMet: 1.395 ± 0.04	2.565LysAsn: 2.565 ± 0.057	2.305LysPro: 2.305 ± 0.05	2.576LysGln: 2.576 ± 0.054	2.775LysArg: 2.775 ± 0.055	2.979LysSer: 2.979 ± 0.062	2.939LysThr: 2.939 ± 0.061	3.297LysVal: 3.297 ± 0.056	0.634LysTrp: 0.634 ± 0.026	1.514LysTyr: 1.514 ± 0.042	0.001LysXaa: 0.001 ± 0.001
Leu	9.968LeuAla: 9.968 ± 0.139	1.328LeuCys: 1.328 ± 0.028	5.454LeuAsp: 5.454 ± 0.074	5.645LeuGlu: 5.645 ± 0.083	4.198LeuPhe: 4.198 ± 0.076	6.566LeuGly: 6.566 ± 0.094	2.26LeuHis: 2.26 ± 0.047	6.562LeuIle: 6.562 ± 0.082	5.093LeuLys: 5.093 ± 0.073	11.064LeuLeu: 11.064 ± 0.149	2.648LeuMet: 2.648 ± 0.05	4.926LeuAsn: 4.926 ± 0.075	5.57LeuPro: 5.57 ± 0.089	4.071LeuGln: 4.071 ± 0.074	5.631LeuArg: 5.631 ± 0.073	8.088LeuSer: 8.088 ± 0.105	6.287LeuThr: 6.287 ± 0.076	6.331LeuVal: 6.331 ± 0.087	1.26LeuTrp: 1.26 ± 0.034	2.74LeuTyr: 2.74 ± 0.052	0.0LeuXaa: 0.0 ± 0.0
Met	2.432MetAla: 2.432 ± 0.05	0.213MetCys: 0.213 ± 0.014	1.146MetAsp: 1.146 ± 0.03	1.308MetGlu: 1.308 ± 0.032	0.79MetPhe: 0.79 ± 0.026	1.589MetGly: 1.589 ± 0.04	0.44MetHis: 0.44 ± 0.019	1.532MetIle: 1.532 ± 0.038	1.539MetLys: 1.539 ± 0.037	2.87MetLeu: 2.87 ± 0.056	0.827MetMet: 0.827 ± 0.032	1.206MetAsn: 1.206 ± 0.036	1.227MetPro: 1.227 ± 0.029	1.096MetGln: 1.096 ± 0.03	1.237MetArg: 1.237 ± 0.037	1.77MetSer: 1.77 ± 0.039	1.679MetThr: 1.679 ± 0.036	1.72MetVal: 1.72 ± 0.037	0.222MetTrp: 0.222 ± 0.014	0.548MetTyr: 0.548 ± 0.023	0.0MetXaa: 0.0 ± 0.0
Asn	3.415AsnAla: 3.415 ± 0.056	0.457AsnCys: 0.457 ± 0.022	2.251AsnAsp: 2.251 ± 0.049	2.452AsnGlu: 2.452 ± 0.044	1.589AsnPhe: 1.589 ± 0.036	3.281AsnGly: 3.281 ± 0.065	1.085AsnHis: 1.085 ± 0.036	3.299AsnIle: 3.299 ± 0.06	2.437AsnLys: 2.437 ± 0.05	4.074AsnLeu: 4.074 ± 0.058	1.079AsnMet: 1.079 ± 0.025	2.309AsnAsn: 2.309 ± 0.055	2.208AsnPro: 2.208 ± 0.043	2.104AsnGln: 2.104 ± 0.046	2.471AsnArg: 2.471 ± 0.045	2.812AsnSer: 2.812 ± 0.058	2.458AsnThr: 2.458 ± 0.049	2.483AsnVal: 2.483 ± 0.05	0.622AsnTrp: 0.622 ± 0.022	1.538AsnTyr: 1.538 ± 0.047	0.0AsnXaa: 0.0 ± 0.0
Pro	3.728ProAla: 3.728 ± 0.066	0.376ProCys: 0.376 ± 0.018	3.025ProAsp: 3.025 ± 0.06	3.468ProGlu: 3.468 ± 0.054	1.764ProPhe: 1.764 ± 0.041	2.938ProGly: 2.938 ± 0.056	0.938ProHis: 0.938 ± 0.028	2.28ProIle: 2.28 ± 0.046	1.824ProLys: 1.824 ± 0.039	4.768ProLeu: 4.768 ± 0.081	0.953ProMet: 0.953 ± 0.037	1.652ProAsn: 1.652 ± 0.04	1.564ProPro: 1.564 ± 0.042	1.907ProGln: 1.907 ± 0.044	1.668ProArg: 1.668 ± 0.036	2.345ProSer: 2.345 ± 0.047	2.12ProThr: 2.12 ± 0.043	3.67ProVal: 3.67 ± 0.058	0.603ProTrp: 0.603 ± 0.026	1.346ProTyr: 1.346 ± 0.033	0.0ProXaa: 0.0 ± 0.0
Gln	4.222GlnAla: 4.222 ± 0.078	0.47GlnCys: 0.47 ± 0.019	2.004GlnAsp: 2.004 ± 0.046	2.572GlnGlu: 2.572 ± 0.062	1.662GlnPhe: 1.662 ± 0.04	3.081GlnGly: 3.081 ± 0.05	1.242GlnHis: 1.242 ± 0.035	2.814GlnIle: 2.814 ± 0.052	2.288GlnLys: 2.288 ± 0.046	5.264GlnLeu: 5.264 ± 0.082	1.061GlnMet: 1.061 ± 0.031	1.631GlnAsn: 1.631 ± 0.042	2.123GlnPro: 2.123 ± 0.047	3.421GlnGln: 3.421 ± 0.075	2.844GlnArg: 2.844 ± 0.063	2.61GlnSer: 2.61 ± 0.051	2.248GlnThr: 2.248 ± 0.048	3.056GlnVal: 3.056 ± 0.063	0.694GlnTrp: 0.694 ± 0.023	1.386GlnTyr: 1.386 ± 0.038	0.001GlnXaa: 0.001 ± 0.001
Arg	3.577ArgAla: 3.577 ± 0.061	0.614ArgCys: 0.614 ± 0.021	2.576ArgAsp: 2.576 ± 0.053	3.398ArgGlu: 3.398 ± 0.061	2.451ArgPhe: 2.451 ± 0.047	3.043ArgGly: 3.043 ± 0.058	1.606ArgHis: 1.606 ± 0.039	3.543ArgIle: 3.543 ± 0.053	2.734ArgLys: 2.734 ± 0.063	6.209ArgLeu: 6.209 ± 0.091	1.398ArgMet: 1.398 ± 0.042	2.229ArgAsn: 2.229 ± 0.047	2.026ArgPro: 2.026 ± 0.038	3.014ArgGln: 3.014 ± 0.056	3.006ArgArg: 3.006 ± 0.055	2.851ArgSer: 2.851 ± 0.052	2.594ArgThr: 2.594 ± 0.053	3.344ArgVal: 3.344 ± 0.053	0.898ArgTrp: 0.898 ± 0.026	2.224ArgTyr: 2.224 ± 0.047	0.0ArgXaa: 0.0 ± 0.0
Ser	5.05SerAla: 5.05 ± 0.077	0.738SerCys: 0.738 ± 0.025	3.606SerAsp: 3.606 ± 0.05	3.686SerGlu: 3.686 ± 0.058	2.494SerPhe: 2.494 ± 0.048	5.32SerGly: 5.32 ± 0.071	1.602SerHis: 1.602 ± 0.042	3.772SerIle: 3.772 ± 0.066	2.681SerLys: 2.681 ± 0.054	7.129SerLeu: 7.129 ± 0.076	1.517SerMet: 1.517 ± 0.034	2.394SerAsn: 2.394 ± 0.049	2.772SerPro: 2.772 ± 0.04	2.964SerGln: 2.964 ± 0.064	3.466SerArg: 3.466 ± 0.055	4.105SerSer: 4.105 ± 0.077	3.008SerThr: 3.008 ± 0.056	4.347SerVal: 4.347 ± 0.07	0.943SerTrp: 0.943 ± 0.029	2.007SerTyr: 2.007 ± 0.039	0.001SerXaa: 0.001 ± 0.001
Thr	4.418ThrAla: 4.418 ± 0.062	0.569ThrCys: 0.569 ± 0.021	2.83ThrAsp: 2.83 ± 0.043	3.198ThrGlu: 3.198 ± 0.046	1.88ThrPhe: 1.88 ± 0.045	4.265ThrGly: 4.265 ± 0.072	1.283ThrHis: 1.283 ± 0.039	3.325ThrIle: 3.325 ± 0.063	2.117ThrLys: 2.117 ± 0.041	6.522ThrLeu: 6.522 ± 0.084	1.058ThrMet: 1.058 ± 0.03	1.855ThrAsn: 1.855 ± 0.04	2.951ThrPro: 2.951 ± 0.055	2.281ThrGln: 2.281 ± 0.045	2.634ThrArg: 2.634 ± 0.054	3.11ThrSer: 3.11 ± 0.054	2.887ThrThr: 2.887 ± 0.061	3.791ThrVal: 3.791 ± 0.058	0.652ThrTrp: 0.652 ± 0.025	1.442ThrTyr: 1.442 ± 0.039	0.001ThrXaa: 0.001 ± 0.001
Val	5.462ValAla: 5.462 ± 0.081	0.772ValCys: 0.772 ± 0.028	3.35ValAsp: 3.35 ± 0.057	3.753ValGlu: 3.753 ± 0.055	2.457ValPhe: 2.457 ± 0.046	4.158ValGly: 4.158 ± 0.074	1.15ValHis: 1.15 ± 0.033	4.782ValIle: 4.782 ± 0.075	3.264ValLys: 3.264 ± 0.059	6.648ValLeu: 6.648 ± 0.077	1.989ValMet: 1.989 ± 0.039	2.935ValAsn: 2.935 ± 0.059	2.83ValPro: 2.83 ± 0.055	2.363ValGln: 2.363 ± 0.047	3.213ValArg: 3.213 ± 0.06	4.643ValSer: 4.643 ± 0.069	3.836ValThr: 3.836 ± 0.059	4.705ValVal: 4.705 ± 0.072	0.816ValTrp: 0.816 ± 0.031	1.795ValTyr: 1.795 ± 0.043	0.001ValXaa: 0.001 ± 0.001
Trp	0.835TrpAla: 0.835 ± 0.025	0.198TrpCys: 0.198 ± 0.014	0.621TrpAsp: 0.621 ± 0.025	0.712TrpGlu: 0.712 ± 0.027	0.599TrpPhe: 0.599 ± 0.023	0.796TrpGly: 0.796 ± 0.03	0.411TrpHis: 0.411 ± 0.021	0.733TrpIle: 0.733 ± 0.028	0.615TrpLys: 0.615 ± 0.023	1.953TrpLeu: 1.953 ± 0.047	0.382TrpMet: 0.382 ± 0.02	0.545TrpAsn: 0.545 ± 0.02	0.529TrpPro: 0.529 ± 0.025	1.155TrpGln: 1.155 ± 0.031	0.969TrpArg: 0.969 ± 0.033	0.852TrpSer: 0.852 ± 0.028	0.48TrpThr: 0.48 ± 0.021	0.866TrpVal: 0.866 ± 0.031	0.189TrpTrp: 0.189 ± 0.014	0.358TrpTyr: 0.358 ± 0.016	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.195TyrAla: 2.195 ± 0.044	0.493TyrCys: 0.493 ± 0.023	1.674TyrAsp: 1.674 ± 0.046	1.559TyrGlu: 1.559 ± 0.038	1.329TyrPhe: 1.329 ± 0.038	2.233TyrGly: 2.233 ± 0.045	0.871TyrHis: 0.871 ± 0.025	1.927TyrIle: 1.927 ± 0.044	1.334TyrLys: 1.334 ± 0.033	3.615TyrLeu: 3.615 ± 0.063	0.731TyrMet: 0.731 ± 0.027	1.282TyrAsn: 1.282 ± 0.035	1.559TyrPro: 1.559 ± 0.04	1.902TyrGln: 1.902 ± 0.044	2.145TyrArg: 2.145 ± 0.046	2.097TyrSer: 2.097 ± 0.049	1.614TyrThr: 1.614 ± 0.037	1.722TyrVal: 1.722 ± 0.039	0.479TyrTrp: 0.479 ± 0.019	1.137TyrTyr: 1.137 ± 0.039	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.002XaaAla: 0.002 ± 0.001	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.003XaaPhe: 0.003 ± 0.002	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.001XaaLys: 0.001 ± 0.001	0.001XaaLeu: 0.001 ± 0.001	0.001XaaMet: 0.001 ± 0.001	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.001XaaGln: 0.001 ± 0.001	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.001XaaVal: 0.001 ± 0.001	0.0XaaTrp: 0.0 ± 0.0	0.001XaaTyr: 0.001 ± 0.001	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 4436 proteins (1160171 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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