Plasmodium malariae

Taxonomy: cellular organisms; Eukaryota; Sar; Alveolata; Apicomplexa; Aconoidasida; Haemosporida; Plasmodiidae; Plasmodium; Plasmodium (Plasmodium)

Average proteome isoelectric point is 7.48

Get precalculated fractions of proteins

Acidic
pI < 6.8
6.8-7.4
pI > 7.4
Basic
    
All



Virtual 2D-PAGE plot for 5915 proteins (isoelectric point calculated using IPC2_protein)

Get csv file with sequences according to given criteria:
        -     Method 

     -  kDa    
                                                                                      

* You can choose from 21 different methods for calculating isoelectric point

Summary statistics related to proteome-wise predictions


    
Protein with the lowest isoelectric point:
>tr|A0A1D3SPA4|A0A1D3SPA4_PLAMA Uncharacterized protein OS=Plasmodium malariae OX=5858 GN=PmUG01_12034300 PE=4 SV=1
MM1 pKa = 7.63EE2 pKa = 4.64FMSYY6 pKa = 10.79NEE8 pKa = 4.08SSNEE12 pKa = 3.54IVQDD16 pKa = 3.69EE17 pKa = 4.26NQEE20 pKa = 3.86EE21 pKa = 4.68GMNVSDD27 pKa = 5.57EE28 pKa = 4.32SLCGKK33 pKa = 9.86GAEE36 pKa = 3.98HH37 pKa = 6.84WEE39 pKa = 4.04DD40 pKa = 3.27VKK42 pKa = 11.69YY43 pKa = 10.73EE44 pKa = 3.95IADD47 pKa = 3.76DD48 pKa = 4.52VFDD51 pKa = 5.37GDD53 pKa = 4.9ANDD56 pKa = 4.29YY57 pKa = 11.48SNDD60 pKa = 3.19YY61 pKa = 10.44CNYY64 pKa = 10.37GGGDD68 pKa = 3.63NNVQRR73 pKa = 11.84SDD75 pKa = 4.34PILEE79 pKa = 4.02EE80 pKa = 4.27AEE82 pKa = 4.05EE83 pKa = 4.19EE84 pKa = 4.24EE85 pKa = 4.37EE86 pKa = 4.17EE87 pKa = 4.26EE88 pKa = 4.2EE89 pKa = 4.21EE90 pKa = 4.21EE91 pKa = 4.21EE92 pKa = 4.21EE93 pKa = 4.21EE94 pKa = 4.21EE95 pKa = 4.21EE96 pKa = 4.21EE97 pKa = 4.21EE98 pKa = 4.21EE99 pKa = 4.21EE100 pKa = 4.21EE101 pKa = 4.21EE102 pKa = 4.21EE103 pKa = 4.32EE104 pKa = 4.49EE105 pKa = 5.03EE106 pKa = 4.76EE107 pKa = 5.21EE108 pKa = 4.61EE109 pKa = 5.95DD110 pKa = 5.8DD111 pKa = 6.3DD112 pKa = 6.39EE113 pKa = 6.63EE114 pKa = 7.24DD115 pKa = 6.13DD116 pKa = 6.58DD117 pKa = 7.44DD118 pKa = 7.62DD119 pKa = 7.7DD120 pKa = 7.69DD121 pKa = 7.68DD122 pKa = 7.62DD123 pKa = 7.62DD124 pKa = 7.66DD125 pKa = 7.37DD126 pKa = 7.09DD127 pKa = 7.33DD128 pKa = 6.58YY129 pKa = 12.12DD130 pKa = 5.19DD131 pKa = 6.26DD132 pKa = 6.19EE133 pKa = 6.21YY134 pKa = 11.78DD135 pKa = 3.47EE136 pKa = 6.54DD137 pKa = 4.75DD138 pKa = 4.12FNEE141 pKa = 4.25ATVSWIEE148 pKa = 3.85WFCQLKK154 pKa = 10.59QNIFLIEE161 pKa = 3.8VDD163 pKa = 3.18EE164 pKa = 4.67DD165 pKa = 4.48FIRR168 pKa = 11.84DD169 pKa = 3.7EE170 pKa = 4.51FNLIGLQNKK179 pKa = 8.46VPHH182 pKa = 6.22FKK184 pKa = 10.67KK185 pKa = 10.37LLKK188 pKa = 10.33IILDD192 pKa = 4.07EE193 pKa = 6.84DD194 pKa = 5.47DD195 pKa = 6.35DD196 pKa = 7.41DD197 pKa = 7.56DD198 pKa = 7.67DD199 pKa = 7.63DD200 pKa = 7.14DD201 pKa = 6.94DD202 pKa = 6.04EE203 pKa = 6.22EE204 pKa = 6.6DD205 pKa = 6.07DD206 pKa = 4.29YY207 pKa = 12.15DD208 pKa = 5.36EE209 pKa = 6.96DD210 pKa = 5.22DD211 pKa = 5.26DD212 pKa = 4.86EE213 pKa = 5.59INRR216 pKa = 11.84GSEE219 pKa = 3.97EE220 pKa = 3.72IYY222 pKa = 10.57KK223 pKa = 10.97NKK225 pKa = 10.37DD226 pKa = 2.77IYY228 pKa = 9.72EE229 pKa = 4.04QNAACLYY236 pKa = 10.34GLIHH240 pKa = 6.74SRR242 pKa = 11.84FILTSKK248 pKa = 10.6GLALMRR254 pKa = 11.84EE255 pKa = 4.52KK256 pKa = 10.63YY257 pKa = 10.28KK258 pKa = 10.97SGIYY262 pKa = 7.6GTCPSIYY269 pKa = 9.91CDD271 pKa = 3.46NAKK274 pKa = 10.36LLPTAISEE282 pKa = 4.45VPKK285 pKa = 10.54FLSPLLYY292 pKa = 10.36CPRR295 pKa = 11.84CCEE298 pKa = 3.42TYY300 pKa = 10.3YY301 pKa = 10.06PHH303 pKa = 7.36KK304 pKa = 10.78NSLINQLDD312 pKa = 3.4GSYY315 pKa = 10.46FGTSFASFFALSFNIQSDD333 pKa = 3.49KK334 pKa = 11.25KK335 pKa = 10.31KK336 pKa = 10.35IYY338 pKa = 7.37YY339 pKa = 8.35TPQICGFTINRR350 pKa = 11.84DD351 pKa = 3.17IRR353 pKa = 11.84EE354 pKa = 4.17TLYY357 pKa = 10.59MDD359 pKa = 3.46MNKK362 pKa = 10.48DD363 pKa = 3.29NSEE366 pKa = 4.0SSEE369 pKa = 4.29EE370 pKa = 4.09YY371 pKa = 10.74SS372 pKa = 3.64

Molecular weight: 43.59 kDa
Isoelectric point according different methods:





Protein with the highest isoelectric point:
>tr|A0A1D3RHV7|A0A1D3RHV7_PLAMA Uncharacterized protein OS=Plasmodium malariae OX=5858 GN=PmUG01_10021400 PE=4 SV=1
MM1 pKa = 7.28AHH3 pKa = 6.31GASRR7 pKa = 11.84YY8 pKa = 8.75KK9 pKa = 10.48KK10 pKa = 10.3SRR12 pKa = 11.84AKK14 pKa = 9.88MRR16 pKa = 11.84WKK18 pKa = 9.16WKK20 pKa = 9.29KK21 pKa = 9.72KK22 pKa = 6.67RR23 pKa = 11.84TRR25 pKa = 11.84RR26 pKa = 11.84LQKK29 pKa = 9.69KK30 pKa = 7.67RR31 pKa = 11.84RR32 pKa = 11.84KK33 pKa = 8.24MRR35 pKa = 11.84QRR37 pKa = 11.84SRR39 pKa = 3.22

Molecular weight: 5.09 kDa
Isoelectric point according different methods:





Peptides (in silico digests for buttom-up proteomics)

Below you can find in silico digests of the whole proteome with Trypsin, Chymotrypsin, Trypsin+LysC, LysN, ArgC proteases suitable for different mass spec machines.

Try
ESI
ChTry
ESI
ArgC
ESI
LysN
ESI
TryLysC
ESI

Try
MALDI
ChTry
MALDI
ArgC
MALDI
LysN
MALDI
TryLysC
MALDI

Try
LTQ
ChTry
LTQ
ArgC
LTQ
LysN
LTQ
TryLysC
LTQ

Try
MSlow
ChTry
MSlow
ArgC
MSlow
LysN
MSlow
TryLysC
MSlow

Try
MShigh
ChTry
MShigh
ArgC
MShigh
LysN
MShigh
TryLysC
MShigh

General Statistics

Number of major isoforms

Number of additional isoforms

Number of all proteins

Number of amino acids

Min. Seq. Length

Max. Seq. Length

Avg. Seq. Length

Avg. Mol. Weight

5915

0

5915

4135924

22

10474

699.2

81.49

Amino acid frequency

Ala

Cys

Asp

Glu

Phe

Gly

His

Ile

Lys

Leu

2.724 ± 0.019

1.917 ± 0.013

5.607 ± 0.026

7.478 ± 0.041

4.6 ± 0.031

3.9 ± 0.027

2.167 ± 0.012

8.221 ± 0.03

11.221 ± 0.04

7.919 ± 0.039

Met

Asn

Gln

Pro

Arg

Ser

Thr

Val

Trp

Tyr

2.049 ± 0.009

11.696 ± 0.078

1.951 ± 0.017

2.544 ± 0.015

3.594 ± 0.02

8.089 ± 0.037

4.283 ± 0.018

4.371 ± 0.017

0.54 ± 0.008

5.128 ± 0.024
Note: For amino acid frequency statistics the error has been estimated with the bootstraping (x100) at the protein level

Most of the basic statistics you can see at this page can be downloaded from this CSV file

For dipeptide frequency statistics click here
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski