Amino acid dipepetide frequency for Wenzhou picorna-like virus 46

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
10.337AlaAla: 10.337 ± 0.0
1.824AlaCys: 1.824 ± 0.0
4.865AlaAsp: 4.865 ± 0.0
6.385AlaGlu: 6.385 ± 0.0
3.649AlaPhe: 3.649 ± 0.0
6.689AlaGly: 6.689 ± 0.0
1.216AlaHis: 1.216 ± 0.0
4.865AlaIle: 4.865 ± 0.0
5.169AlaLys: 5.169 ± 0.0
6.993AlaLeu: 6.993 ± 0.0
1.824AlaMet: 1.824 ± 0.0
2.736AlaAsn: 2.736 ± 0.0
4.865AlaPro: 4.865 ± 0.0
4.257AlaGln: 4.257 ± 0.0
3.344AlaArg: 3.344 ± 0.0
5.473AlaSer: 5.473 ± 0.0
6.385AlaThr: 6.385 ± 0.0
5.473AlaVal: 5.473 ± 0.0
1.216AlaTrp: 1.216 ± 0.0
0.608AlaTyr: 0.608 ± 0.0
0.0AlaXaa: 0.0 ± 0.0
Cys
0.912CysAla: 0.912 ± 0.0
1.216CysCys: 1.216 ± 0.0
0.0CysAsp: 0.0 ± 0.0
1.216CysGlu: 1.216 ± 0.0
0.304CysPhe: 0.304 ± 0.0
1.52CysGly: 1.52 ± 0.0
0.0CysHis: 0.0 ± 0.0
1.216CysIle: 1.216 ± 0.0
0.304CysLys: 0.304 ± 0.0
1.216CysLeu: 1.216 ± 0.0
0.304CysMet: 0.304 ± 0.0
0.304CysAsn: 0.304 ± 0.0
0.912CysPro: 0.912 ± 0.0
0.912CysGln: 0.912 ± 0.0
0.912CysArg: 0.912 ± 0.0
2.128CysSer: 2.128 ± 0.0
2.432CysThr: 2.432 ± 0.0
0.608CysVal: 0.608 ± 0.0
0.608CysTrp: 0.608 ± 0.0
1.52CysTyr: 1.52 ± 0.0
0.0CysXaa: 0.0 ± 0.0
Asp
5.777AspAla: 5.777 ± 0.0
0.608AspCys: 0.608 ± 0.0
2.128AspAsp: 2.128 ± 0.0
2.432AspGlu: 2.432 ± 0.0
0.304AspPhe: 0.304 ± 0.0
3.953AspGly: 3.953 ± 0.0
1.824AspHis: 1.824 ± 0.0
3.953AspIle: 3.953 ± 0.0
3.649AspLys: 3.649 ± 0.0
4.561AspLeu: 4.561 ± 0.0
1.216AspMet: 1.216 ± 0.0
2.432AspAsn: 2.432 ± 0.0
3.953AspPro: 3.953 ± 0.0
2.128AspGln: 2.128 ± 0.0
3.649AspArg: 3.649 ± 0.0
3.953AspSer: 3.953 ± 0.0
3.649AspThr: 3.649 ± 0.0
3.04AspVal: 3.04 ± 0.0
1.52AspTrp: 1.52 ± 0.0
0.912AspTyr: 0.912 ± 0.0
0.0AspXaa: 0.0 ± 0.0
Glu
5.169GluAla: 5.169 ± 0.0
1.52GluCys: 1.52 ± 0.0
1.52GluAsp: 1.52 ± 0.0
1.216GluGlu: 1.216 ± 0.0
3.04GluPhe: 3.04 ± 0.0
3.649GluGly: 3.649 ± 0.0
1.216GluHis: 1.216 ± 0.0
2.432GluIle: 2.432 ± 0.0
2.128GluLys: 2.128 ± 0.0
5.169GluLeu: 5.169 ± 0.0
1.52GluMet: 1.52 ± 0.0
1.216GluAsn: 1.216 ± 0.0
0.912GluPro: 0.912 ± 0.0
2.736GluGln: 2.736 ± 0.0
2.736GluArg: 2.736 ± 0.0
3.04GluSer: 3.04 ± 0.0
3.04GluThr: 3.04 ± 0.0
4.561GluVal: 4.561 ± 0.0
0.304GluTrp: 0.304 ± 0.0
0.912GluTyr: 0.912 ± 0.0
0.0GluXaa: 0.0 ± 0.0
Phe
3.04PheAla: 3.04 ± 0.0
1.216PheCys: 1.216 ± 0.0
2.432PheAsp: 2.432 ± 0.0
0.912PheGlu: 0.912 ± 0.0
0.608PhePhe: 0.608 ± 0.0
2.736PheGly: 2.736 ± 0.0
0.608PheHis: 0.608 ± 0.0
1.216PheIle: 1.216 ± 0.0
1.824PheLys: 1.824 ± 0.0
2.128PheLeu: 2.128 ± 0.0
0.912PheMet: 0.912 ± 0.0
1.52PheAsn: 1.52 ± 0.0
2.736PhePro: 2.736 ± 0.0
0.912PheGln: 0.912 ± 0.0
0.912PheArg: 0.912 ± 0.0
4.257PheSer: 4.257 ± 0.0
3.04PheThr: 3.04 ± 0.0
1.824PheVal: 1.824 ± 0.0
0.912PheTrp: 0.912 ± 0.0
0.608PheTyr: 0.608 ± 0.0
0.0PheXaa: 0.0 ± 0.0
Gly
6.689GlyAla: 6.689 ± 0.0
1.52GlyCys: 1.52 ± 0.0
3.04GlyAsp: 3.04 ± 0.0
3.04GlyGlu: 3.04 ± 0.0
3.04GlyPhe: 3.04 ± 0.0
3.04GlyGly: 3.04 ± 0.0
1.216GlyHis: 1.216 ± 0.0
2.128GlyIle: 2.128 ± 0.0
4.865GlyLys: 4.865 ± 0.0
6.081GlyLeu: 6.081 ± 0.0
2.432GlyMet: 2.432 ± 0.0
3.04GlyAsn: 3.04 ± 0.0
1.52GlyPro: 1.52 ± 0.0
2.736GlyGln: 2.736 ± 0.0
2.736GlyArg: 2.736 ± 0.0
6.689GlySer: 6.689 ± 0.0
4.257GlyThr: 4.257 ± 0.0
4.865GlyVal: 4.865 ± 0.0
0.304GlyTrp: 0.304 ± 0.0
1.52GlyTyr: 1.52 ± 0.0
0.0GlyXaa: 0.0 ± 0.0
His
1.824HisAla: 1.824 ± 0.0
0.304HisCys: 0.304 ± 0.0
1.216HisAsp: 1.216 ± 0.0
0.0HisGlu: 0.0 ± 0.0
0.304HisPhe: 0.304 ± 0.0
0.912HisGly: 0.912 ± 0.0
0.912HisHis: 0.912 ± 0.0
2.432HisIle: 2.432 ± 0.0
0.912HisLys: 0.912 ± 0.0
0.912HisLeu: 0.912 ± 0.0
0.608HisMet: 0.608 ± 0.0
0.608HisAsn: 0.608 ± 0.0
0.912HisPro: 0.912 ± 0.0
1.52HisGln: 1.52 ± 0.0
1.824HisArg: 1.824 ± 0.0
0.608HisSer: 0.608 ± 0.0
1.52HisThr: 1.52 ± 0.0
0.912HisVal: 0.912 ± 0.0
0.912HisTrp: 0.912 ± 0.0
1.52HisTyr: 1.52 ± 0.0
0.0HisXaa: 0.0 ± 0.0
Ile
4.865IleAla: 4.865 ± 0.0
1.216IleCys: 1.216 ± 0.0
3.04IleAsp: 3.04 ± 0.0
1.52IleGlu: 1.52 ± 0.0
1.216IlePhe: 1.216 ± 0.0
4.257IleGly: 4.257 ± 0.0
0.608IleHis: 0.608 ± 0.0
2.432IleIle: 2.432 ± 0.0
3.04IleLys: 3.04 ± 0.0
6.385IleLeu: 6.385 ± 0.0
1.52IleMet: 1.52 ± 0.0
2.432IleAsn: 2.432 ± 0.0
3.649IlePro: 3.649 ± 0.0
3.649IleGln: 3.649 ± 0.0
0.912IleArg: 0.912 ± 0.0
3.04IleSer: 3.04 ± 0.0
3.344IleThr: 3.344 ± 0.0
3.649IleVal: 3.649 ± 0.0
0.304IleTrp: 0.304 ± 0.0
1.52IleTyr: 1.52 ± 0.0
0.0IleXaa: 0.0 ± 0.0
Lys
4.257LysAla: 4.257 ± 0.0
1.52LysCys: 1.52 ± 0.0
2.736LysAsp: 2.736 ± 0.0
2.432LysGlu: 2.432 ± 0.0
1.216LysPhe: 1.216 ± 0.0
3.04LysGly: 3.04 ± 0.0
1.216LysHis: 1.216 ± 0.0
3.344LysIle: 3.344 ± 0.0
5.473LysLys: 5.473 ± 0.0
8.209LysLeu: 8.209 ± 0.0
0.608LysMet: 0.608 ± 0.0
2.128LysAsn: 2.128 ± 0.0
2.736LysPro: 2.736 ± 0.0
2.736LysGln: 2.736 ± 0.0
2.128LysArg: 2.128 ± 0.0
3.04LysSer: 3.04 ± 0.0
3.04LysThr: 3.04 ± 0.0
4.561LysVal: 4.561 ± 0.0
0.608LysTrp: 0.608 ± 0.0
3.04LysTyr: 3.04 ± 0.0
0.0LysXaa: 0.0 ± 0.0
Leu
8.209LeuAla: 8.209 ± 0.0
2.432LeuCys: 2.432 ± 0.0
4.561LeuAsp: 4.561 ± 0.0
3.344LeuGlu: 3.344 ± 0.0
2.432LeuPhe: 2.432 ± 0.0
4.257LeuGly: 4.257 ± 0.0
1.824LeuHis: 1.824 ± 0.0
3.649LeuIle: 3.649 ± 0.0
6.993LeuLys: 6.993 ± 0.0
6.385LeuLeu: 6.385 ± 0.0
3.344LeuMet: 3.344 ± 0.0
4.257LeuAsn: 4.257 ± 0.0
6.689LeuPro: 6.689 ± 0.0
3.344LeuGln: 3.344 ± 0.0
3.344LeuArg: 3.344 ± 0.0
3.04LeuSer: 3.04 ± 0.0
3.649LeuThr: 3.649 ± 0.0
6.081LeuVal: 6.081 ± 0.0
1.52LeuTrp: 1.52 ± 0.0
2.736LeuTyr: 2.736 ± 0.0
0.0LeuXaa: 0.0 ± 0.0
Met
1.824MetAla: 1.824 ± 0.0
0.304MetCys: 0.304 ± 0.0
1.824MetAsp: 1.824 ± 0.0
1.824MetGlu: 1.824 ± 0.0
0.304MetPhe: 0.304 ± 0.0
0.608MetGly: 0.608 ± 0.0
0.608MetHis: 0.608 ± 0.0
0.608MetIle: 0.608 ± 0.0
1.52MetLys: 1.52 ± 0.0
2.736MetLeu: 2.736 ± 0.0
0.304MetMet: 0.304 ± 0.0
0.608MetAsn: 0.608 ± 0.0
0.608MetPro: 0.608 ± 0.0
1.216MetGln: 1.216 ± 0.0
1.52MetArg: 1.52 ± 0.0
1.216MetSer: 1.216 ± 0.0
2.128MetThr: 2.128 ± 0.0
2.736MetVal: 2.736 ± 0.0
0.608MetTrp: 0.608 ± 0.0
1.52MetTyr: 1.52 ± 0.0
0.0MetXaa: 0.0 ± 0.0
Asn
4.257AsnAla: 4.257 ± 0.0
0.608AsnCys: 0.608 ± 0.0
2.432AsnAsp: 2.432 ± 0.0
0.608AsnGlu: 0.608 ± 0.0
1.216AsnPhe: 1.216 ± 0.0
1.52AsnGly: 1.52 ± 0.0
0.912AsnHis: 0.912 ± 0.0
3.04AsnIle: 3.04 ± 0.0
2.128AsnLys: 2.128 ± 0.0
2.432AsnLeu: 2.432 ± 0.0
2.128AsnMet: 2.128 ± 0.0
2.432AsnAsn: 2.432 ± 0.0
4.257AsnPro: 4.257 ± 0.0
2.432AsnGln: 2.432 ± 0.0
0.608AsnArg: 0.608 ± 0.0
3.04AsnSer: 3.04 ± 0.0
4.257AsnThr: 4.257 ± 0.0
4.561AsnVal: 4.561 ± 0.0
0.304AsnTrp: 0.304 ± 0.0
0.912AsnTyr: 0.912 ± 0.0
0.0AsnXaa: 0.0 ± 0.0
Pro
4.257ProAla: 4.257 ± 0.0
0.0ProCys: 0.0 ± 0.0
3.344ProAsp: 3.344 ± 0.0
3.344ProGlu: 3.344 ± 0.0
2.736ProPhe: 2.736 ± 0.0
4.257ProGly: 4.257 ± 0.0
0.304ProHis: 0.304 ± 0.0
3.953ProIle: 3.953 ± 0.0
3.953ProLys: 3.953 ± 0.0
4.257ProLeu: 4.257 ± 0.0
1.824ProMet: 1.824 ± 0.0
2.128ProAsn: 2.128 ± 0.0
3.344ProPro: 3.344 ± 0.0
3.344ProGln: 3.344 ± 0.0
2.736ProArg: 2.736 ± 0.0
3.344ProSer: 3.344 ± 0.0
3.649ProThr: 3.649 ± 0.0
4.257ProVal: 4.257 ± 0.0
1.52ProTrp: 1.52 ± 0.0
0.912ProTyr: 0.912 ± 0.0
0.0ProXaa: 0.0 ± 0.0
Gln
3.953GlnAla: 3.953 ± 0.0
0.0GlnCys: 0.0 ± 0.0
2.736GlnAsp: 2.736 ± 0.0
2.432GlnGlu: 2.432 ± 0.0
1.52GlnPhe: 1.52 ± 0.0
1.52GlnGly: 1.52 ± 0.0
0.608GlnHis: 0.608 ± 0.0
2.736GlnIle: 2.736 ± 0.0
2.128GlnLys: 2.128 ± 0.0
6.385GlnLeu: 6.385 ± 0.0
0.912GlnMet: 0.912 ± 0.0
2.736GlnAsn: 2.736 ± 0.0
2.128GlnPro: 2.128 ± 0.0
3.649GlnGln: 3.649 ± 0.0
1.824GlnArg: 1.824 ± 0.0
3.04GlnSer: 3.04 ± 0.0
3.344GlnThr: 3.344 ± 0.0
2.432GlnVal: 2.432 ± 0.0
1.52GlnTrp: 1.52 ± 0.0
2.432GlnTyr: 2.432 ± 0.0
0.0GlnXaa: 0.0 ± 0.0
Arg
2.736ArgAla: 2.736 ± 0.0
0.912ArgCys: 0.912 ± 0.0
2.432ArgAsp: 2.432 ± 0.0
3.344ArgGlu: 3.344 ± 0.0
2.128ArgPhe: 2.128 ± 0.0
3.344ArgGly: 3.344 ± 0.0
0.304ArgHis: 0.304 ± 0.0
2.736ArgIle: 2.736 ± 0.0
1.824ArgLys: 1.824 ± 0.0
4.865ArgLeu: 4.865 ± 0.0
0.608ArgMet: 0.608 ± 0.0
2.128ArgAsn: 2.128 ± 0.0
1.52ArgPro: 1.52 ± 0.0
2.736ArgGln: 2.736 ± 0.0
1.52ArgArg: 1.52 ± 0.0
3.344ArgSer: 3.344 ± 0.0
1.52ArgThr: 1.52 ± 0.0
2.432ArgVal: 2.432 ± 0.0
0.912ArgTrp: 0.912 ± 0.0
1.52ArgTyr: 1.52 ± 0.0
0.0ArgXaa: 0.0 ± 0.0
Ser
5.473SerAla: 5.473 ± 0.0
0.608SerCys: 0.608 ± 0.0
5.169SerAsp: 5.169 ± 0.0
4.257SerGlu: 4.257 ± 0.0
3.344SerPhe: 3.344 ± 0.0
6.081SerGly: 6.081 ± 0.0
2.432SerHis: 2.432 ± 0.0
2.736SerIle: 2.736 ± 0.0
2.736SerLys: 2.736 ± 0.0
3.344SerLeu: 3.344 ± 0.0
0.608SerMet: 0.608 ± 0.0
1.824SerAsn: 1.824 ± 0.0
5.169SerPro: 5.169 ± 0.0
2.432SerGln: 2.432 ± 0.0
3.04SerArg: 3.04 ± 0.0
6.689SerSer: 6.689 ± 0.0
5.169SerThr: 5.169 ± 0.0
4.561SerVal: 4.561 ± 0.0
1.216SerTrp: 1.216 ± 0.0
1.52SerTyr: 1.52 ± 0.0
0.0SerXaa: 0.0 ± 0.0
Thr
5.169ThrAla: 5.169 ± 0.0
0.608ThrCys: 0.608 ± 0.0
3.649ThrAsp: 3.649 ± 0.0
3.344ThrGlu: 3.344 ± 0.0
2.736ThrPhe: 2.736 ± 0.0
5.473ThrGly: 5.473 ± 0.0
2.432ThrHis: 2.432 ± 0.0
2.736ThrIle: 2.736 ± 0.0
2.736ThrLys: 2.736 ± 0.0
4.257ThrLeu: 4.257 ± 0.0
1.52ThrMet: 1.52 ± 0.0
3.953ThrAsn: 3.953 ± 0.0
3.953ThrPro: 3.953 ± 0.0
4.257ThrGln: 4.257 ± 0.0
3.04ThrArg: 3.04 ± 0.0
4.561ThrSer: 4.561 ± 0.0
6.385ThrThr: 6.385 ± 0.0
6.081ThrVal: 6.081 ± 0.0
0.912ThrTrp: 0.912 ± 0.0
1.824ThrTyr: 1.824 ± 0.0
0.0ThrXaa: 0.0 ± 0.0
Val
6.081ValAla: 6.081 ± 0.0
1.52ValCys: 1.52 ± 0.0
4.865ValAsp: 4.865 ± 0.0
3.953ValGlu: 3.953 ± 0.0
2.736ValPhe: 2.736 ± 0.0
5.169ValGly: 5.169 ± 0.0
1.824ValHis: 1.824 ± 0.0
4.257ValIle: 4.257 ± 0.0
3.953ValLys: 3.953 ± 0.0
3.04ValLeu: 3.04 ± 0.0
1.52ValMet: 1.52 ± 0.0
3.649ValAsn: 3.649 ± 0.0
4.561ValPro: 4.561 ± 0.0
1.52ValGln: 1.52 ± 0.0
4.561ValArg: 4.561 ± 0.0
4.865ValSer: 4.865 ± 0.0
3.344ValThr: 3.344 ± 0.0
6.689ValVal: 6.689 ± 0.0
0.912ValTrp: 0.912 ± 0.0
3.953ValTyr: 3.953 ± 0.0
0.0ValXaa: 0.0 ± 0.0
Trp
0.304TrpAla: 0.304 ± 0.0
0.608TrpCys: 0.608 ± 0.0
0.912TrpAsp: 0.912 ± 0.0
1.216TrpGlu: 1.216 ± 0.0
0.304TrpPhe: 0.304 ± 0.0
0.608TrpGly: 0.608 ± 0.0
0.0TrpHis: 0.0 ± 0.0
1.52TrpIle: 1.52 ± 0.0
1.52TrpLys: 1.52 ± 0.0
0.912TrpLeu: 0.912 ± 0.0
0.608TrpMet: 0.608 ± 0.0
0.912TrpAsn: 0.912 ± 0.0
0.608TrpPro: 0.608 ± 0.0
0.304TrpGln: 0.304 ± 0.0
0.304TrpArg: 0.304 ± 0.0
0.912TrpSer: 0.912 ± 0.0
3.04TrpThr: 3.04 ± 0.0
2.128TrpVal: 2.128 ± 0.0
0.304TrpTrp: 0.304 ± 0.0
0.0TrpTyr: 0.0 ± 0.0
0.0TrpXaa: 0.0 ± 0.0
Tyr
3.04TyrAla: 3.04 ± 0.0
0.0TyrCys: 0.0 ± 0.0
2.736TyrAsp: 2.736 ± 0.0
1.216TyrGlu: 1.216 ± 0.0
1.216TyrPhe: 1.216 ± 0.0
2.128TyrGly: 2.128 ± 0.0
0.608TyrHis: 0.608 ± 0.0
0.608TyrIle: 0.608 ± 0.0
1.216TyrLys: 1.216 ± 0.0
1.824TyrLeu: 1.824 ± 0.0
0.0TyrMet: 0.0 ± 0.0
3.04TyrAsn: 3.04 ± 0.0
2.432TyrPro: 2.432 ± 0.0
1.216TyrGln: 1.216 ± 0.0
1.216TyrArg: 1.216 ± 0.0
2.128TyrSer: 2.128 ± 0.0
2.432TyrThr: 2.432 ± 0.0
1.52TyrVal: 1.52 ± 0.0
0.912TyrTrp: 0.912 ± 0.0
2.432TyrTyr: 2.432 ± 0.0
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 1 proteins (3290 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski