Amino acid dipepetide frequency for Mosquito VEM virus SDBVL G

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
1.152AlaAla: 1.152 ± 1.033
0.0AlaCys: 0.0 ± 0.0
6.912AlaAsp: 6.912 ± 2.892
2.304AlaGlu: 2.304 ± 3.026
2.304AlaPhe: 2.304 ± 0.964
2.304AlaGly: 2.304 ± 0.964
0.0AlaHis: 0.0 ± 0.0
4.608AlaIle: 4.608 ± 3.005
3.456AlaLys: 3.456 ± 1.449
3.456AlaLeu: 3.456 ± 1.484
1.152AlaMet: 1.152 ± 0.954
2.304AlaAsn: 2.304 ± 1.446
1.152AlaPro: 1.152 ± 0.811
2.304AlaGln: 2.304 ± 1.253
6.912AlaArg: 6.912 ± 1.132
5.76AlaSer: 5.76 ± 1.868
3.456AlaThr: 3.456 ± 1.831
5.76AlaVal: 5.76 ± 2.49
1.152AlaTrp: 1.152 ± 0.811
2.304AlaTyr: 2.304 ± 0.964
0.0AlaXaa: 0.0 ± 0.0
Cys
0.0CysAla: 0.0 ± 0.0
0.0CysCys: 0.0 ± 0.0
1.152CysAsp: 1.152 ± 1.033
1.152CysGlu: 1.152 ± 1.037
0.0CysPhe: 0.0 ± 0.0
1.152CysGly: 1.152 ± 1.513
0.0CysHis: 0.0 ± 0.0
0.0CysIle: 0.0 ± 0.0
0.0CysLys: 0.0 ± 0.0
1.152CysLeu: 1.152 ± 1.033
0.0CysMet: 0.0 ± 0.0
1.152CysAsn: 1.152 ± 1.037
1.152CysPro: 1.152 ± 1.033
1.152CysGln: 1.152 ± 1.513
0.0CysArg: 0.0 ± 0.0
1.152CysSer: 1.152 ± 0.811
2.304CysThr: 2.304 ± 1.253
2.304CysVal: 2.304 ± 1.597
0.0CysTrp: 0.0 ± 0.0
1.152CysTyr: 1.152 ± 0.811
0.0CysXaa: 0.0 ± 0.0
Asp
4.608AspAla: 4.608 ± 1.591
0.0AspCys: 0.0 ± 0.0
2.304AspAsp: 2.304 ± 1.446
3.456AspGlu: 3.456 ± 2.432
3.456AspPhe: 3.456 ± 0.824
1.152AspGly: 1.152 ± 1.037
0.0AspHis: 0.0 ± 0.0
3.456AspIle: 3.456 ± 2.227
2.304AspLys: 2.304 ± 1.446
3.456AspLeu: 3.456 ± 0.824
3.456AspMet: 3.456 ± 1.473
4.608AspAsn: 4.608 ± 1.928
5.76AspPro: 5.76 ± 3.001
0.0AspGln: 0.0 ± 0.0
1.152AspArg: 1.152 ± 1.037
4.608AspSer: 4.608 ± 1.978
3.456AspThr: 3.456 ± 1.484
5.76AspVal: 5.76 ± 2.629
3.456AspTrp: 3.456 ± 1.831
2.304AspTyr: 2.304 ± 2.074
0.0AspXaa: 0.0 ± 0.0
Glu
4.608GluAla: 4.608 ± 4.385
0.0GluCys: 0.0 ± 0.0
4.608GluAsp: 4.608 ± 2.102
8.065GluGlu: 8.065 ± 3.186
1.152GluPhe: 1.152 ± 1.513
2.304GluGly: 2.304 ± 1.253
1.152GluHis: 1.152 ± 1.037
2.304GluIle: 2.304 ± 1.253
1.152GluLys: 1.152 ± 0.811
3.456GluLeu: 3.456 ± 1.244
1.152GluMet: 1.152 ± 1.033
2.304GluAsn: 2.304 ± 2.066
1.152GluPro: 1.152 ± 1.037
3.456GluGln: 3.456 ± 0.824
3.456GluArg: 3.456 ± 1.831
1.152GluSer: 1.152 ± 1.033
3.456GluThr: 3.456 ± 1.484
4.608GluVal: 4.608 ± 1.365
1.152GluTrp: 1.152 ± 0.811
3.456GluTyr: 3.456 ± 1.605
0.0GluXaa: 0.0 ± 0.0
Phe
2.304PheAla: 2.304 ± 0.964
2.304PheCys: 2.304 ± 1.597
3.456PheAsp: 3.456 ± 1.244
1.152PheGlu: 1.152 ± 1.033
2.304PhePhe: 2.304 ± 1.597
4.608PheGly: 4.608 ± 0.911
1.152PheHis: 1.152 ± 1.037
1.152PheIle: 1.152 ± 0.811
3.456PheLys: 3.456 ± 1.791
3.456PheLeu: 3.456 ± 2.056
1.152PheMet: 1.152 ± 1.251
1.152PheAsn: 1.152 ± 0.811
2.304PhePro: 2.304 ± 1.446
1.152PheGln: 1.152 ± 1.513
2.304PheArg: 2.304 ± 0.964
4.608PheSer: 4.608 ± 2.507
2.304PheThr: 2.304 ± 1.621
1.152PheVal: 1.152 ± 1.513
1.152PheTrp: 1.152 ± 1.037
1.152PheTyr: 1.152 ± 0.811
0.0PheXaa: 0.0 ± 0.0
Gly
4.608GlyAla: 4.608 ± 2.178
1.152GlyCys: 1.152 ± 1.513
5.76GlyAsp: 5.76 ± 1.467
1.152GlyGlu: 1.152 ± 1.033
3.456GlyPhe: 3.456 ± 2.432
13.825GlyGly: 13.825 ± 6.976
1.152GlyHis: 1.152 ± 0.811
5.76GlyIle: 5.76 ± 0.631
4.608GlyLys: 4.608 ± 2.597
5.76GlyLeu: 5.76 ± 2.49
0.0GlyMet: 0.0 ± 0.0
1.152GlyAsn: 1.152 ± 1.037
4.608GlyPro: 4.608 ± 2.177
0.0GlyGln: 0.0 ± 0.0
5.76GlyArg: 5.76 ± 1.961
4.608GlySer: 4.608 ± 1.928
8.065GlyThr: 8.065 ± 1.098
1.152GlyVal: 1.152 ± 1.033
1.152GlyTrp: 1.152 ± 1.033
1.152GlyTyr: 1.152 ± 0.811
0.0GlyXaa: 0.0 ± 0.0
His
1.152HisAla: 1.152 ± 1.037
0.0HisCys: 0.0 ± 0.0
2.304HisAsp: 2.304 ± 1.597
2.304HisGlu: 2.304 ± 0.964
1.152HisPhe: 1.152 ± 1.037
0.0HisGly: 0.0 ± 0.0
0.0HisHis: 0.0 ± 0.0
0.0HisIle: 0.0 ± 0.0
0.0HisLys: 0.0 ± 0.0
2.304HisLeu: 2.304 ± 1.597
0.0HisMet: 0.0 ± 0.0
1.152HisAsn: 1.152 ± 0.811
3.456HisPro: 3.456 ± 0.824
0.0HisGln: 0.0 ± 0.0
1.152HisArg: 1.152 ± 0.811
1.152HisSer: 1.152 ± 1.037
0.0HisThr: 0.0 ± 0.0
0.0HisVal: 0.0 ± 0.0
2.304HisTrp: 2.304 ± 1.699
1.152HisTyr: 1.152 ± 1.037
0.0HisXaa: 0.0 ± 0.0
Ile
2.304IleAla: 2.304 ± 2.074
1.152IleCys: 1.152 ± 1.037
1.152IleAsp: 1.152 ± 1.037
1.152IleGlu: 1.152 ± 1.033
1.152IlePhe: 1.152 ± 1.033
2.304IleGly: 2.304 ± 1.253
1.152IleHis: 1.152 ± 1.037
1.152IleIle: 1.152 ± 1.037
4.608IleLys: 4.608 ± 3.193
2.304IleLeu: 2.304 ± 0.989
0.0IleMet: 0.0 ± 0.0
2.304IleAsn: 2.304 ± 0.989
2.304IlePro: 2.304 ± 1.621
3.456IleGln: 3.456 ± 1.394
3.456IleArg: 3.456 ± 1.831
3.456IleSer: 3.456 ± 0.824
2.304IleThr: 2.304 ± 2.066
3.456IleVal: 3.456 ± 1.449
2.304IleTrp: 2.304 ± 1.699
2.304IleTyr: 2.304 ± 1.621
0.0IleXaa: 0.0 ± 0.0
Lys
3.456LysAla: 3.456 ± 1.244
0.0LysCys: 0.0 ± 0.0
2.304LysAsp: 2.304 ± 2.074
3.456LysGlu: 3.456 ± 1.244
3.456LysPhe: 3.456 ± 2.227
3.456LysGly: 3.456 ± 1.791
0.0LysHis: 0.0 ± 0.0
1.152LysIle: 1.152 ± 0.811
1.152LysLys: 1.152 ± 0.811
1.152LysLeu: 1.152 ± 1.513
1.152LysMet: 1.152 ± 1.033
1.152LysAsn: 1.152 ± 1.513
2.304LysPro: 2.304 ± 1.446
4.608LysGln: 4.608 ± 2.14
3.456LysArg: 3.456 ± 2.432
1.152LysSer: 1.152 ± 1.033
1.152LysThr: 1.152 ± 1.513
1.152LysVal: 1.152 ± 0.811
1.152LysTrp: 1.152 ± 1.513
1.152LysTyr: 1.152 ± 1.037
0.0LysXaa: 0.0 ± 0.0
Leu
2.304LeuAla: 2.304 ± 0.964
3.456LeuCys: 3.456 ± 2.05
2.304LeuAsp: 2.304 ± 1.597
4.608LeuGlu: 4.608 ± 1.978
3.456LeuPhe: 3.456 ± 2.846
4.608LeuGly: 4.608 ± 2.857
1.152LeuHis: 1.152 ± 1.037
5.76LeuIle: 5.76 ± 1.885
2.304LeuLys: 2.304 ± 0.989
5.76LeuLeu: 5.76 ± 2.556
1.152LeuMet: 1.152 ± 0.811
2.304LeuAsn: 2.304 ± 0.989
5.76LeuPro: 5.76 ± 2.565
1.152LeuGln: 1.152 ± 1.033
6.912LeuArg: 6.912 ± 3.568
3.456LeuSer: 3.456 ± 1.484
2.304LeuThr: 2.304 ± 0.964
3.456LeuVal: 3.456 ± 1.244
2.304LeuTrp: 2.304 ± 1.621
4.608LeuTyr: 4.608 ± 4.323
0.0LeuXaa: 0.0 ± 0.0
Met
0.0MetAla: 0.0 ± 0.0
0.0MetCys: 0.0 ± 0.0
0.0MetAsp: 0.0 ± 0.0
1.152MetGlu: 1.152 ± 1.513
1.152MetPhe: 1.152 ± 0.811
1.152MetGly: 1.152 ± 0.811
1.152MetHis: 1.152 ± 0.811
0.0MetIle: 0.0 ± 0.0
0.0MetLys: 0.0 ± 0.0
2.304MetLeu: 2.304 ± 0.989
1.152MetMet: 1.152 ± 1.033
0.0MetAsn: 0.0 ± 0.0
4.608MetPro: 4.608 ± 2.994
1.152MetGln: 1.152 ± 1.033
1.152MetArg: 1.152 ± 1.033
2.304MetSer: 2.304 ± 1.699
2.304MetThr: 2.304 ± 1.446
2.304MetVal: 2.304 ± 1.621
0.0MetTrp: 0.0 ± 0.0
1.152MetTyr: 1.152 ± 0.811
0.0MetXaa: 0.0 ± 0.0
Asn
3.456AsnAla: 3.456 ± 2.432
3.456AsnCys: 3.456 ± 1.394
6.912AsnAsp: 6.912 ± 2.427
2.304AsnGlu: 2.304 ± 0.964
1.152AsnPhe: 1.152 ± 1.037
1.152AsnGly: 1.152 ± 0.811
0.0AsnHis: 0.0 ± 0.0
4.608AsnIle: 4.608 ± 1.928
1.152AsnLys: 1.152 ± 1.037
1.152AsnLeu: 1.152 ± 0.811
3.456AsnMet: 3.456 ± 3.099
3.456AsnAsn: 3.456 ± 1.853
0.0AsnPro: 0.0 ± 0.0
0.0AsnGln: 0.0 ± 0.0
1.152AsnArg: 1.152 ± 0.811
4.608AsnSer: 4.608 ± 2.178
2.304AsnThr: 2.304 ± 1.699
2.304AsnVal: 2.304 ± 0.989
2.304AsnTrp: 2.304 ± 1.597
0.0AsnTyr: 0.0 ± 0.0
0.0AsnXaa: 0.0 ± 0.0
Pro
0.0ProAla: 0.0 ± 0.0
0.0ProCys: 0.0 ± 0.0
1.152ProAsp: 1.152 ± 1.033
8.065ProGlu: 8.065 ± 4.206
2.304ProPhe: 2.304 ± 0.989
9.217ProGly: 9.217 ± 2.705
0.0ProHis: 0.0 ± 0.0
0.0ProIle: 0.0 ± 0.0
1.152ProLys: 1.152 ± 1.033
3.456ProLeu: 3.456 ± 0.824
0.0ProMet: 0.0 ± 0.0
3.456ProAsn: 3.456 ± 1.449
4.608ProPro: 4.608 ± 2.507
1.152ProGln: 1.152 ± 0.811
6.912ProArg: 6.912 ± 0.796
8.065ProSer: 8.065 ± 4.38
9.217ProThr: 9.217 ± 4.626
2.304ProVal: 2.304 ± 0.989
1.152ProTrp: 1.152 ± 1.037
3.456ProTyr: 3.456 ± 1.449
0.0ProXaa: 0.0 ± 0.0
Gln
3.456GlnAla: 3.456 ± 1.791
0.0GlnCys: 0.0 ± 0.0
2.304GlnAsp: 2.304 ± 0.989
0.0GlnGlu: 0.0 ± 0.0
1.152GlnPhe: 1.152 ± 1.033
2.304GlnGly: 2.304 ± 1.699
2.304GlnHis: 2.304 ± 2.074
1.152GlnIle: 1.152 ± 1.033
0.0GlnLys: 0.0 ± 0.0
2.304GlnLeu: 2.304 ± 0.989
0.0GlnMet: 0.0 ± 0.0
2.304GlnAsn: 2.304 ± 2.066
4.608GlnPro: 4.608 ± 1.978
0.0GlnGln: 0.0 ± 0.0
0.0GlnArg: 0.0 ± 0.0
1.152GlnSer: 1.152 ± 0.811
1.152GlnThr: 1.152 ± 0.811
4.608GlnVal: 4.608 ± 1.365
0.0GlnTrp: 0.0 ± 0.0
0.0GlnTyr: 0.0 ± 0.0
0.0GlnXaa: 0.0 ± 0.0
Arg
5.76ArgAla: 5.76 ± 2.323
2.304ArgCys: 2.304 ± 0.964
3.456ArgAsp: 3.456 ± 1.791
2.304ArgGlu: 2.304 ± 1.253
3.456ArgPhe: 3.456 ± 2.056
3.456ArgGly: 3.456 ± 0.824
2.304ArgHis: 2.304 ± 1.597
4.608ArgIle: 4.608 ± 1.05
4.608ArgLys: 4.608 ± 2.14
3.456ArgLeu: 3.456 ± 1.449
1.152ArgMet: 1.152 ± 0.811
3.456ArgAsn: 3.456 ± 0.824
4.608ArgPro: 4.608 ± 2.815
2.304ArgGln: 2.304 ± 2.066
16.129ArgArg: 16.129 ± 5.54
8.065ArgSer: 8.065 ± 1.098
11.521ArgThr: 11.521 ± 2.447
2.304ArgVal: 2.304 ± 0.964
1.152ArgTrp: 1.152 ± 0.811
1.152ArgTyr: 1.152 ± 0.811
0.0ArgXaa: 0.0 ± 0.0
Ser
3.456SerAla: 3.456 ± 1.853
1.152SerCys: 1.152 ± 1.033
1.152SerAsp: 1.152 ± 1.037
5.76SerGlu: 5.76 ± 1.499
3.456SerPhe: 3.456 ± 2.227
5.76SerGly: 5.76 ± 1.467
1.152SerHis: 1.152 ± 1.033
3.456SerIle: 3.456 ± 1.394
1.152SerLys: 1.152 ± 1.037
9.217SerLeu: 9.217 ± 2.61
3.456SerMet: 3.456 ± 1.484
4.608SerAsn: 4.608 ± 2.374
3.456SerPro: 3.456 ± 2.432
2.304SerGln: 2.304 ± 2.066
8.065SerArg: 8.065 ± 2.597
8.065SerSer: 8.065 ± 2.399
6.912SerThr: 6.912 ± 2.697
4.608SerVal: 4.608 ± 1.978
1.152SerTrp: 1.152 ± 0.811
2.304SerTyr: 2.304 ± 1.446
0.0SerXaa: 0.0 ± 0.0
Thr
4.608ThrAla: 4.608 ± 2.14
0.0ThrCys: 0.0 ± 0.0
3.456ThrAsp: 3.456 ± 1.394
3.456ThrGlu: 3.456 ± 2.056
2.304ThrPhe: 2.304 ± 1.621
5.76ThrGly: 5.76 ± 1.885
1.152ThrHis: 1.152 ± 1.513
1.152ThrIle: 1.152 ± 1.033
0.0ThrLys: 0.0 ± 0.0
3.456ThrLeu: 3.456 ± 3.099
1.152ThrMet: 1.152 ± 1.451
4.608ThrAsn: 4.608 ± 1.05
9.217ThrPro: 9.217 ± 1.722
1.152ThrGln: 1.152 ± 0.811
6.912ThrArg: 6.912 ± 2.892
11.521ThrSer: 11.521 ± 4.945
5.76ThrThr: 5.76 ± 3.84
2.304ThrVal: 2.304 ± 1.699
0.0ThrTrp: 0.0 ± 0.0
5.76ThrTyr: 5.76 ± 2.323
0.0ThrXaa: 0.0 ± 0.0
Val
1.152ValAla: 1.152 ± 1.037
0.0ValCys: 0.0 ± 0.0
2.304ValAsp: 2.304 ± 0.989
2.304ValGlu: 2.304 ± 1.597
5.76ValPhe: 5.76 ± 2.49
9.217ValGly: 9.217 ± 4.281
1.152ValHis: 1.152 ± 1.513
1.152ValIle: 1.152 ± 1.037
4.608ValLys: 4.608 ± 2.892
5.76ValLeu: 5.76 ± 3.994
0.0ValMet: 0.0 ± 0.0
1.152ValAsn: 1.152 ± 0.811
4.608ValPro: 4.608 ± 2.815
1.152ValGln: 1.152 ± 0.811
3.456ValArg: 3.456 ± 0.824
1.152ValSer: 1.152 ± 1.513
3.456ValThr: 3.456 ± 1.449
1.152ValVal: 1.152 ± 1.037
1.152ValTrp: 1.152 ± 1.513
4.608ValTyr: 4.608 ± 2.178
0.0ValXaa: 0.0 ± 0.0
Trp
3.456TrpAla: 3.456 ± 1.244
0.0TrpCys: 0.0 ± 0.0
2.304TrpAsp: 2.304 ± 1.253
0.0TrpGlu: 0.0 ± 0.0
0.0TrpPhe: 0.0 ± 0.0
1.152TrpGly: 1.152 ± 1.513
3.456TrpHis: 3.456 ± 1.449
0.0TrpIle: 0.0 ± 0.0
1.152TrpLys: 1.152 ± 1.037
4.608TrpLeu: 4.608 ± 1.521
1.152TrpMet: 1.152 ± 1.513
1.152TrpAsn: 1.152 ± 0.811
0.0TrpPro: 0.0 ± 0.0
0.0TrpGln: 0.0 ± 0.0
1.152TrpArg: 1.152 ± 0.811
1.152TrpSer: 1.152 ± 1.033
2.304TrpThr: 2.304 ± 0.964
1.152TrpVal: 1.152 ± 1.513
0.0TrpTrp: 0.0 ± 0.0
0.0TrpTyr: 0.0 ± 0.0
0.0TrpXaa: 0.0 ± 0.0
Tyr
6.912TyrAla: 6.912 ± 2.371
0.0TyrCys: 0.0 ± 0.0
3.456TyrAsp: 3.456 ± 1.449
0.0TyrGlu: 0.0 ± 0.0
1.152TyrPhe: 1.152 ± 1.513
0.0TyrGly: 0.0 ± 0.0
1.152TyrHis: 1.152 ± 1.033
2.304TyrIle: 2.304 ± 1.253
1.152TyrLys: 1.152 ± 1.513
1.152TyrLeu: 1.152 ± 0.811
1.152TyrMet: 1.152 ± 0.811
1.152TyrAsn: 1.152 ± 0.811
0.0TyrPro: 0.0 ± 0.0
2.304TyrGln: 2.304 ± 1.621
8.065TyrArg: 8.065 ± 2.373
3.456TyrSer: 3.456 ± 1.244
1.152TyrThr: 1.152 ± 0.811
3.456TyrVal: 3.456 ± 1.449
1.152TyrTrp: 1.152 ± 0.811
1.152TyrTyr: 1.152 ± 0.811
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 4 proteins (869 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski