Amino acid dipepetide frequency for Mesta yellow vein mosaic virus

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
5.479AlaAla: 5.479 ± 1.964
0.0AlaCys: 0.0 ± 0.0
0.913AlaAsp: 0.913 ± 0.712
0.0AlaGlu: 0.0 ± 0.0
0.0AlaPhe: 0.0 ± 0.0
1.826AlaGly: 1.826 ± 0.686
1.826AlaHis: 1.826 ± 1.0
3.653AlaIle: 3.653 ± 1.086
3.653AlaLys: 3.653 ± 1.269
3.653AlaLeu: 3.653 ± 1.716
0.0AlaMet: 0.0 ± 0.0
3.653AlaAsn: 3.653 ± 1.18
3.653AlaPro: 3.653 ± 1.18
5.479AlaGln: 5.479 ± 1.64
3.653AlaArg: 3.653 ± 1.837
3.653AlaSer: 3.653 ± 1.732
2.74AlaThr: 2.74 ± 2.136
2.74AlaVal: 2.74 ± 0.832
1.826AlaTrp: 1.826 ± 0.871
1.826AlaTyr: 1.826 ± 0.871
0.0AlaXaa: 0.0 ± 0.0
Cys
0.0CysAla: 0.0 ± 0.0
0.0CysCys: 0.0 ± 0.0
0.913CysAsp: 0.913 ± 0.945
0.913CysGlu: 0.913 ± 0.712
1.826CysPhe: 1.826 ± 1.22
1.826CysGly: 1.826 ± 0.877
0.0CysHis: 0.0 ± 0.0
0.0CysIle: 0.0 ± 0.0
0.913CysLys: 0.913 ± 0.712
0.913CysLeu: 0.913 ± 0.712
2.74CysMet: 2.74 ± 1.332
2.74CysAsn: 2.74 ± 1.036
1.826CysPro: 1.826 ± 1.889
0.913CysGln: 0.913 ± 0.61
1.826CysArg: 1.826 ± 1.0
3.653CysSer: 3.653 ± 1.664
0.913CysThr: 0.913 ± 0.9
0.913CysVal: 0.913 ± 0.712
0.0CysTrp: 0.0 ± 0.0
0.0CysTyr: 0.0 ± 0.0
0.0CysXaa: 0.0 ± 0.0
Asp
3.653AspAla: 3.653 ± 1.622
0.0AspCys: 0.0 ± 0.0
1.826AspAsp: 1.826 ± 0.877
0.913AspGlu: 0.913 ± 0.712
1.826AspPhe: 1.826 ± 0.686
2.74AspGly: 2.74 ± 1.83
1.826AspHis: 1.826 ± 1.22
3.653AspIle: 3.653 ± 1.28
0.913AspLys: 0.913 ± 0.61
8.219AspLeu: 8.219 ± 2.874
0.0AspMet: 0.0 ± 0.0
0.913AspAsn: 0.913 ± 0.712
2.74AspPro: 2.74 ± 1.036
2.74AspGln: 2.74 ± 1.293
3.653AspArg: 3.653 ± 1.28
2.74AspSer: 2.74 ± 0.988
0.913AspThr: 0.913 ± 0.944
4.566AspVal: 4.566 ± 1.317
1.826AspTrp: 1.826 ± 0.877
0.0AspTyr: 0.0 ± 0.0
0.0AspXaa: 0.0 ± 0.0
Glu
4.566GluAla: 4.566 ± 1.602
0.913GluCys: 0.913 ± 0.9
1.826GluAsp: 1.826 ± 0.871
9.132GluGlu: 9.132 ± 4.583
2.74GluPhe: 2.74 ± 1.361
6.393GluGly: 6.393 ± 1.945
0.0GluHis: 0.0 ± 0.0
0.913GluIle: 0.913 ± 0.885
0.913GluLys: 0.913 ± 0.61
4.566GluLeu: 4.566 ± 1.818
0.0GluMet: 0.0 ± 0.0
2.74GluAsn: 2.74 ± 1.258
2.74GluPro: 2.74 ± 0.832
3.653GluGln: 3.653 ± 1.442
0.0GluArg: 0.0 ± 0.0
2.74GluSer: 2.74 ± 1.177
2.74GluThr: 2.74 ± 1.361
1.826GluVal: 1.826 ± 1.195
2.74GluTrp: 2.74 ± 1.213
0.913GluTyr: 0.913 ± 0.944
0.0GluXaa: 0.0 ± 0.0
Phe
0.0PheAla: 0.0 ± 0.0
0.913PheCys: 0.913 ± 0.712
3.653PheAsp: 3.653 ± 1.28
1.826PheGlu: 1.826 ± 0.877
0.913PhePhe: 0.913 ± 0.61
0.0PheGly: 0.0 ± 0.0
1.826PheHis: 1.826 ± 1.22
0.913PheIle: 0.913 ± 0.61
3.653PheLys: 3.653 ± 1.742
5.479PheLeu: 5.479 ± 1.861
0.913PheMet: 0.913 ± 0.61
3.653PheAsn: 3.653 ± 0.894
0.913PhePro: 0.913 ± 0.944
5.479PheGln: 5.479 ± 1.739
2.74PheArg: 2.74 ± 1.506
3.653PheSer: 3.653 ± 1.947
0.913PheThr: 0.913 ± 0.9
2.74PheVal: 2.74 ± 1.085
0.913PheTrp: 0.913 ± 0.712
1.826PheTyr: 1.826 ± 1.07
0.0PheXaa: 0.0 ± 0.0
Gly
4.566GlyAla: 4.566 ± 1.362
2.74GlyCys: 2.74 ± 1.838
1.826GlyAsp: 1.826 ± 1.22
1.826GlyGlu: 1.826 ± 1.338
1.826GlyPhe: 1.826 ± 1.175
2.74GlyGly: 2.74 ± 1.085
2.74GlyHis: 2.74 ± 0.826
3.653GlyIle: 3.653 ± 0.988
6.393GlyLys: 6.393 ± 2.56
2.74GlyLeu: 2.74 ± 1.293
0.0GlyMet: 0.0 ± 0.0
0.913GlyAsn: 0.913 ± 0.945
3.653GlyPro: 3.653 ± 0.988
3.653GlyGln: 3.653 ± 1.18
0.913GlyArg: 0.913 ± 0.61
5.479GlySer: 5.479 ± 2.039
4.566GlyThr: 4.566 ± 1.097
1.826GlyVal: 1.826 ± 1.77
0.0GlyTrp: 0.0 ± 0.0
0.913GlyTyr: 0.913 ± 0.944
0.0GlyXaa: 0.0 ± 0.0
His
0.0HisAla: 0.0 ± 0.0
2.74HisCys: 2.74 ± 1.868
0.0HisAsp: 0.0 ± 0.0
1.826HisGlu: 1.826 ± 0.871
3.653HisPhe: 3.653 ± 1.857
2.74HisGly: 2.74 ± 1.868
0.913HisHis: 0.913 ± 0.9
0.913HisIle: 0.913 ± 0.945
0.913HisLys: 0.913 ± 0.944
2.74HisLeu: 2.74 ± 1.343
0.913HisMet: 0.913 ± 0.712
2.74HisAsn: 2.74 ± 1.213
1.826HisPro: 1.826 ± 0.871
0.913HisGln: 0.913 ± 0.712
2.74HisArg: 2.74 ± 1.838
0.0HisSer: 0.0 ± 0.0
1.826HisThr: 1.826 ± 1.424
2.74HisVal: 2.74 ± 1.225
0.0HisTrp: 0.0 ± 0.0
0.0HisTyr: 0.0 ± 0.0
0.0HisXaa: 0.0 ± 0.0
Ile
0.0IleAla: 0.0 ± 0.0
2.74IleCys: 2.74 ± 0.988
2.74IleAsp: 2.74 ± 1.83
0.913IleGlu: 0.913 ± 0.61
2.74IlePhe: 2.74 ± 1.83
1.826IleGly: 1.826 ± 1.424
0.0IleHis: 0.0 ± 0.0
2.74IleIle: 2.74 ± 1.819
6.393IleLys: 6.393 ± 0.988
2.74IleLeu: 2.74 ± 1.225
0.0IleMet: 0.0 ± 0.0
0.913IleAsn: 0.913 ± 0.9
0.913IlePro: 0.913 ± 0.61
4.566IleGln: 4.566 ± 1.69
3.653IleArg: 3.653 ± 1.503
4.566IleSer: 4.566 ± 1.127
2.74IleThr: 2.74 ± 1.646
2.74IleVal: 2.74 ± 1.258
2.74IleTrp: 2.74 ± 1.819
1.826IleTyr: 1.826 ± 1.22
0.0IleXaa: 0.0 ± 0.0
Lys
0.0LysAla: 0.0 ± 0.0
2.74LysCys: 2.74 ± 1.216
2.74LysAsp: 2.74 ± 1.213
4.566LysGlu: 4.566 ± 2.197
2.74LysPhe: 2.74 ± 0.832
2.74LysGly: 2.74 ± 0.826
0.913LysHis: 0.913 ± 0.61
3.653LysIle: 3.653 ± 1.002
0.913LysLys: 0.913 ± 0.61
0.913LysLeu: 0.913 ± 0.885
0.0LysMet: 0.0 ± 0.0
7.306LysAsn: 7.306 ± 2.077
2.74LysPro: 2.74 ± 0.918
0.0LysGln: 0.0 ± 0.0
3.653LysArg: 3.653 ± 2.129
6.393LysSer: 6.393 ± 1.715
2.74LysThr: 2.74 ± 0.832
5.479LysVal: 5.479 ± 1.759
0.0LysTrp: 0.0 ± 0.0
3.653LysTyr: 3.653 ± 1.086
0.0LysXaa: 0.0 ± 0.0
Leu
1.826LeuAla: 1.826 ± 1.0
3.653LeuCys: 3.653 ± 1.134
2.74LeuAsp: 2.74 ± 1.213
6.393LeuGlu: 6.393 ± 1.924
2.74LeuPhe: 2.74 ± 1.954
3.653LeuGly: 3.653 ± 1.703
2.74LeuHis: 2.74 ± 1.216
2.74LeuIle: 2.74 ± 1.847
5.479LeuLys: 5.479 ± 2.05
4.566LeuLeu: 4.566 ± 1.82
1.826LeuMet: 1.826 ± 1.37
6.393LeuAsn: 6.393 ± 1.236
0.913LeuPro: 0.913 ± 0.9
3.653LeuGln: 3.653 ± 1.23
8.219LeuArg: 8.219 ± 2.679
5.479LeuSer: 5.479 ± 0.774
8.219LeuThr: 8.219 ± 3.005
0.913LeuVal: 0.913 ± 0.61
0.0LeuTrp: 0.0 ± 0.0
5.479LeuTyr: 5.479 ± 2.394
0.0LeuXaa: 0.0 ± 0.0
Met
0.0MetAla: 0.0 ± 0.0
0.0MetCys: 0.0 ± 0.0
2.74MetAsp: 2.74 ± 1.819
0.913MetGlu: 0.913 ± 0.9
1.826MetPhe: 1.826 ± 1.141
2.74MetGly: 2.74 ± 0.988
0.0MetHis: 0.0 ± 0.0
0.0MetIle: 0.0 ± 0.0
0.0MetLys: 0.0 ± 0.0
1.826MetLeu: 1.826 ± 1.07
0.0MetMet: 0.0 ± 0.0
0.0MetAsn: 0.0 ± 0.0
1.826MetPro: 1.826 ± 0.686
0.0MetGln: 0.0 ± 0.0
1.826MetArg: 1.826 ± 0.877
0.913MetSer: 0.913 ± 0.712
0.0MetThr: 0.0 ± 0.0
0.0MetVal: 0.0 ± 0.0
2.74MetTrp: 2.74 ± 0.918
3.653MetTyr: 3.653 ± 2.203
0.0MetXaa: 0.0 ± 0.0
Asn
3.653AsnAla: 3.653 ± 1.716
0.913AsnCys: 0.913 ± 0.9
4.566AsnAsp: 4.566 ± 1.896
1.826AsnGlu: 1.826 ± 1.07
1.826AsnPhe: 1.826 ± 1.141
1.826AsnGly: 1.826 ± 0.988
3.653AsnHis: 3.653 ± 2.195
1.826AsnIle: 1.826 ± 0.686
0.913AsnLys: 0.913 ± 0.885
6.393AsnLeu: 6.393 ± 2.108
1.826AsnMet: 1.826 ± 1.057
1.826AsnAsn: 1.826 ± 1.064
5.479AsnPro: 5.479 ± 1.811
1.826AsnGln: 1.826 ± 1.22
2.74AsnArg: 2.74 ± 0.826
1.826AsnSer: 1.826 ± 1.311
2.74AsnThr: 2.74 ± 1.085
3.653AsnVal: 3.653 ± 1.134
0.913AsnTrp: 0.913 ± 0.61
4.566AsnTyr: 4.566 ± 1.107
0.0AsnXaa: 0.0 ± 0.0
Pro
3.653ProAla: 3.653 ± 1.41
1.826ProCys: 1.826 ± 1.07
1.826ProAsp: 1.826 ± 1.07
1.826ProGlu: 1.826 ± 1.0
0.913ProPhe: 0.913 ± 0.61
0.913ProGly: 0.913 ± 0.61
3.653ProHis: 3.653 ± 1.857
3.653ProIle: 3.653 ± 1.722
3.653ProLys: 3.653 ± 1.622
6.393ProLeu: 6.393 ± 2.0
1.826ProMet: 1.826 ± 1.059
4.566ProAsn: 4.566 ± 0.835
2.74ProPro: 2.74 ± 1.216
3.653ProGln: 3.653 ± 1.947
4.566ProArg: 4.566 ± 1.602
5.479ProSer: 5.479 ± 3.677
6.393ProThr: 6.393 ± 2.503
0.913ProVal: 0.913 ± 0.61
0.0ProTrp: 0.0 ± 0.0
2.74ProTyr: 2.74 ± 0.832
0.0ProXaa: 0.0 ± 0.0
Gln
3.653GlnAla: 3.653 ± 1.726
0.0GlnCys: 0.0 ± 0.0
1.826GlnAsp: 1.826 ± 1.175
3.653GlnGlu: 3.653 ± 1.18
3.653GlnPhe: 3.653 ± 1.716
1.826GlnGly: 1.826 ± 1.22
3.653GlnHis: 3.653 ± 2.621
1.826GlnIle: 1.826 ± 1.22
1.826GlnLys: 1.826 ± 1.175
2.74GlnLeu: 2.74 ± 1.036
0.0GlnMet: 0.0 ± 0.0
3.653GlnAsn: 3.653 ± 1.664
3.653GlnPro: 3.653 ± 2.061
4.566GlnGln: 4.566 ± 1.156
2.74GlnArg: 2.74 ± 0.988
3.653GlnSer: 3.653 ± 1.622
3.653GlnThr: 3.653 ± 1.242
6.393GlnVal: 6.393 ± 2.504
0.0GlnTrp: 0.0 ± 0.0
1.826GlnTyr: 1.826 ± 1.061
0.0GlnXaa: 0.0 ± 0.0
Arg
2.74ArgAla: 2.74 ± 1.819
0.913ArgCys: 0.913 ± 0.944
3.653ArgAsp: 3.653 ± 1.304
3.653ArgGlu: 3.653 ± 1.947
3.653ArgPhe: 3.653 ± 1.925
4.566ArgGly: 4.566 ± 1.746
1.826ArgHis: 1.826 ± 1.889
3.653ArgIle: 3.653 ± 1.678
3.653ArgLys: 3.653 ± 1.679
2.74ArgLeu: 2.74 ± 1.394
2.74ArgMet: 2.74 ± 2.136
3.653ArgAsn: 3.653 ± 1.235
5.479ArgPro: 5.479 ± 1.759
1.826ArgGln: 1.826 ± 1.273
7.306ArgArg: 7.306 ± 2.703
7.306ArgSer: 7.306 ± 1.593
3.653ArgThr: 3.653 ± 1.804
6.393ArgVal: 6.393 ± 1.731
0.0ArgTrp: 0.0 ± 0.0
0.913ArgTyr: 0.913 ± 0.944
0.0ArgXaa: 0.0 ± 0.0
Ser
4.566SerAla: 4.566 ± 1.848
1.826SerCys: 1.826 ± 1.889
3.653SerAsp: 3.653 ± 1.586
6.393SerGlu: 6.393 ± 1.993
2.74SerPhe: 2.74 ± 0.826
4.566SerGly: 4.566 ± 1.59
0.913SerHis: 0.913 ± 0.885
3.653SerIle: 3.653 ± 1.235
5.479SerLys: 5.479 ± 1.457
6.393SerLeu: 6.393 ± 1.014
1.826SerMet: 1.826 ± 0.939
3.653SerAsn: 3.653 ± 1.242
9.132SerPro: 9.132 ± 1.748
3.653SerGln: 3.653 ± 1.848
5.479SerArg: 5.479 ± 1.782
18.265SerSer: 18.265 ± 6.532
6.393SerThr: 6.393 ± 2.791
0.0SerVal: 0.0 ± 0.0
0.0SerTrp: 0.0 ± 0.0
3.653SerTyr: 3.653 ± 1.23
0.0SerXaa: 0.0 ± 0.0
Thr
4.566ThrAla: 4.566 ± 1.435
0.913ThrCys: 0.913 ± 0.945
0.913ThrAsp: 0.913 ± 0.945
1.826ThrGlu: 1.826 ± 1.273
1.826ThrPhe: 1.826 ± 1.195
4.566ThrGly: 4.566 ± 1.577
2.74ThrHis: 2.74 ± 1.838
0.913ThrIle: 0.913 ± 0.61
3.653ThrLys: 3.653 ± 1.371
4.566ThrLeu: 4.566 ± 0.985
2.74ThrMet: 2.74 ± 0.95
1.826ThrAsn: 1.826 ± 0.686
5.479ThrPro: 5.479 ± 1.275
2.74ThrGln: 2.74 ± 1.025
3.653ThrArg: 3.653 ± 2.283
2.74ThrSer: 2.74 ± 1.835
1.826ThrThr: 1.826 ± 1.195
7.306ThrVal: 7.306 ± 3.726
0.913ThrTrp: 0.913 ± 0.945
1.826ThrTyr: 1.826 ± 0.988
0.0ThrXaa: 0.0 ± 0.0
Val
0.913ValAla: 0.913 ± 0.712
0.0ValCys: 0.0 ± 0.0
4.566ValAsp: 4.566 ± 1.676
1.826ValGlu: 1.826 ± 1.889
2.74ValPhe: 2.74 ± 1.284
3.653ValGly: 3.653 ± 2.139
0.913ValHis: 0.913 ± 0.944
5.479ValIle: 5.479 ± 1.479
3.653ValLys: 3.653 ± 1.371
5.479ValLeu: 5.479 ± 1.664
0.913ValMet: 0.913 ± 0.712
0.913ValAsn: 0.913 ± 0.712
3.653ValPro: 3.653 ± 0.894
4.566ValGln: 4.566 ± 1.602
4.566ValArg: 4.566 ± 2.59
5.479ValSer: 5.479 ± 1.826
3.653ValThr: 3.653 ± 1.925
1.826ValVal: 1.826 ± 0.686
0.0ValTrp: 0.0 ± 0.0
2.74ValTyr: 2.74 ± 1.258
0.0ValXaa: 0.0 ± 0.0
Trp
3.653TrpAla: 3.653 ± 1.622
0.0TrpCys: 0.0 ± 0.0
0.913TrpAsp: 0.913 ± 0.944
0.913TrpGlu: 0.913 ± 0.885
0.0TrpPhe: 0.0 ± 0.0
0.913TrpGly: 0.913 ± 0.61
0.0TrpHis: 0.0 ± 0.0
0.913TrpIle: 0.913 ± 0.712
0.0TrpLys: 0.0 ± 0.0
0.0TrpLeu: 0.0 ± 0.0
0.913TrpMet: 0.913 ± 0.712
0.0TrpAsn: 0.0 ± 0.0
0.0TrpPro: 0.0 ± 0.0
0.913TrpGln: 0.913 ± 0.61
0.913TrpArg: 0.913 ± 0.9
2.74TrpSer: 2.74 ± 1.465
0.913TrpThr: 0.913 ± 0.885
0.0TrpVal: 0.0 ± 0.0
0.0TrpTrp: 0.0 ± 0.0
0.913TrpTyr: 0.913 ± 0.61
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.74TyrAla: 2.74 ± 1.258
0.0TyrCys: 0.0 ± 0.0
1.826TyrAsp: 1.826 ± 1.07
0.913TyrGlu: 0.913 ± 0.712
2.74TyrPhe: 2.74 ± 0.832
0.913TyrGly: 0.913 ± 0.61
0.0TyrHis: 0.0 ± 0.0
2.74TyrIle: 2.74 ± 1.216
0.913TyrLys: 0.913 ± 0.61
4.566TyrLeu: 4.566 ± 1.75
0.913TyrMet: 0.913 ± 0.839
3.653TyrAsn: 3.653 ± 1.575
1.826TyrPro: 1.826 ± 1.0
0.0TyrGln: 0.0 ± 0.0
5.479TyrArg: 5.479 ± 2.885
5.479TyrSer: 5.479 ± 2.105
0.0TyrThr: 0.0 ± 0.0
4.566TyrVal: 4.566 ± 1.858
0.0TyrTrp: 0.0 ± 0.0
0.913TyrTyr: 0.913 ± 0.9
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 6 proteins (1096 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski