Amino acid dipepetide frequency for Sphingomonas jatrophae

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	24.546AlaAla: 24.546 ± 0.257	1.126AlaCys: 1.126 ± 0.031	8.555AlaAsp: 8.555 ± 0.106	8.661AlaGlu: 8.661 ± 0.1	4.452AlaPhe: 4.452 ± 0.067	13.498AlaGly: 13.498 ± 0.18	2.374AlaHis: 2.374 ± 0.046	6.36AlaIle: 6.36 ± 0.078	3.666AlaLys: 3.666 ± 0.068	15.68AlaLeu: 15.68 ± 0.169	3.79AlaMet: 3.79 ± 0.066	2.932AlaAsn: 2.932 ± 0.063	7.345AlaPro: 7.345 ± 0.134	4.697AlaGln: 4.697 ± 0.071	11.768AlaArg: 11.768 ± 0.141	6.461AlaSer: 6.461 ± 0.091	7.463AlaThr: 7.463 ± 0.131	9.523AlaVal: 9.523 ± 0.102	1.888AlaTrp: 1.888 ± 0.042	2.63AlaTyr: 2.63 ± 0.043	0.0AlaXaa: 0.0 ± 0.0
Cys	1.005CysAla: 1.005 ± 0.031	0.072CysCys: 0.072 ± 0.008	0.468CysAsp: 0.468 ± 0.021	0.332CysGlu: 0.332 ± 0.018	0.251CysPhe: 0.251 ± 0.015	0.839CysGly: 0.839 ± 0.029	0.177CysHis: 0.177 ± 0.013	0.307CysIle: 0.307 ± 0.018	0.129CysLys: 0.129 ± 0.009	0.67CysLeu: 0.67 ± 0.025	0.117CysMet: 0.117 ± 0.009	0.159CysAsn: 0.159 ± 0.013	0.447CysPro: 0.447 ± 0.02	0.151CysGln: 0.151 ± 0.011	0.573CysArg: 0.573 ± 0.026	0.352CysSer: 0.352 ± 0.016	0.407CysThr: 0.407 ± 0.019	0.496CysVal: 0.496 ± 0.023	0.1CysTrp: 0.1 ± 0.009	0.156CysTyr: 0.156 ± 0.01	0.0CysXaa: 0.0 ± 0.0
Asp	8.718AspAla: 8.718 ± 0.099	0.407AspCys: 0.407 ± 0.018	3.179AspAsp: 3.179 ± 0.062	3.425AspGlu: 3.425 ± 0.063	1.979AspPhe: 1.979 ± 0.041	5.829AspGly: 5.829 ± 0.08	1.219AspHis: 1.219 ± 0.035	2.418AspIle: 2.418 ± 0.061	1.427AspLys: 1.427 ± 0.037	5.913AspLeu: 5.913 ± 0.07	1.283AspMet: 1.283 ± 0.033	1.066AspAsn: 1.066 ± 0.033	4.027AspPro: 4.027 ± 0.066	1.643AspGln: 1.643 ± 0.038	5.172AspArg: 5.172 ± 0.076	1.928AspSer: 1.928 ± 0.04	2.639AspThr: 2.639 ± 0.066	4.214AspVal: 4.214 ± 0.074	1.074AspTrp: 1.074 ± 0.028	1.591AspTyr: 1.591 ± 0.042	0.0AspXaa: 0.0 ± 0.0
Glu	8.539GluAla: 8.539 ± 0.12	0.263GluCys: 0.263 ± 0.014	2.614GluAsp: 2.614 ± 0.047	2.754GluGlu: 2.754 ± 0.063	1.238GluPhe: 1.238 ± 0.038	4.595GluGly: 4.595 ± 0.062	1.029GluHis: 1.029 ± 0.03	2.611GluIle: 2.611 ± 0.048	1.377GluLys: 1.377 ± 0.041	4.845GluLeu: 4.845 ± 0.069	1.209GluMet: 1.209 ± 0.031	0.947GluAsn: 0.947 ± 0.03	2.784GluPro: 2.784 ± 0.051	2.106GluGln: 2.106 ± 0.041	5.428GluArg: 5.428 ± 0.09	1.9GluSer: 1.9 ± 0.047	3.127GluThr: 3.127 ± 0.057	3.718GluVal: 3.718 ± 0.055	0.74GluTrp: 0.74 ± 0.026	0.826GluTyr: 0.826 ± 0.025	0.0GluXaa: 0.0 ± 0.0
Phe	4.942PheAla: 4.942 ± 0.07	0.282PheCys: 0.282 ± 0.016	2.597PheAsp: 2.597 ± 0.042	1.867PheGlu: 1.867 ± 0.046	1.106PhePhe: 1.106 ± 0.034	3.477PheGly: 3.477 ± 0.053	0.666PheHis: 0.666 ± 0.021	1.153PheIle: 1.153 ± 0.029	0.704PheLys: 0.704 ± 0.024	2.844PheLeu: 2.844 ± 0.057	0.617PheMet: 0.617 ± 0.021	0.889PheAsn: 0.889 ± 0.028	1.335PhePro: 1.335 ± 0.033	0.805PheGln: 0.805 ± 0.027	2.314PheArg: 2.314 ± 0.045	1.727PheSer: 1.727 ± 0.039	1.898PheThr: 1.898 ± 0.038	2.687PheVal: 2.687 ± 0.05	0.499PheTrp: 0.499 ± 0.024	0.806PheTyr: 0.806 ± 0.027	0.0PheXaa: 0.0 ± 0.0
Gly	11.515GlyAla: 11.515 ± 0.159	0.825GlyCys: 0.825 ± 0.024	5.033GlyAsp: 5.033 ± 0.082	4.96GlyGlu: 4.96 ± 0.073	3.543GlyPhe: 3.543 ± 0.064	9.4GlyGly: 9.4 ± 0.21	1.808GlyHis: 1.808 ± 0.044	4.155GlyIle: 4.155 ± 0.064	2.583GlyLys: 2.583 ± 0.048	9.045GlyLeu: 9.045 ± 0.097	2.273GlyMet: 2.273 ± 0.047	2.141GlyAsn: 2.141 ± 0.079	3.86GlyPro: 3.86 ± 0.064	2.994GlyGln: 2.994 ± 0.057	7.714GlyArg: 7.714 ± 0.101	4.82GlySer: 4.82 ± 0.106	5.332GlyThr: 5.332 ± 0.152	6.587GlyVal: 6.587 ± 0.082	1.748GlyTrp: 1.748 ± 0.043	2.309GlyTyr: 2.309 ± 0.054	0.0GlyXaa: 0.0 ± 0.0
His	2.491HisAla: 2.491 ± 0.05	0.189HisCys: 0.189 ± 0.012	1.21HisAsp: 1.21 ± 0.031	0.917HisGlu: 0.917 ± 0.03	0.688HisPhe: 0.688 ± 0.024	1.947HisGly: 1.947 ± 0.041	0.527HisHis: 0.527 ± 0.02	0.733HisIle: 0.733 ± 0.024	0.377HisLys: 0.377 ± 0.019	1.848HisLeu: 1.848 ± 0.046	0.383HisMet: 0.383 ± 0.017	0.37HisAsn: 0.37 ± 0.017	1.314HisPro: 1.314 ± 0.039	0.499HisGln: 0.499 ± 0.022	1.513HisArg: 1.513 ± 0.039	0.733HisSer: 0.733 ± 0.027	0.64HisThr: 0.64 ± 0.025	1.518HisVal: 1.518 ± 0.036	0.307HisTrp: 0.307 ± 0.018	0.485HisTyr: 0.485 ± 0.024	0.0HisXaa: 0.0 ± 0.0
Ile	7.306IleAla: 7.306 ± 0.08	0.373IleCys: 0.373 ± 0.018	3.661IleAsp: 3.661 ± 0.062	3.157IleGlu: 3.157 ± 0.052	1.254IlePhe: 1.254 ± 0.034	4.749IleGly: 4.749 ± 0.061	0.793IleHis: 0.793 ± 0.026	1.407IleIle: 1.407 ± 0.037	0.954IleLys: 0.954 ± 0.032	3.611IleLeu: 3.611 ± 0.059	0.644IleMet: 0.644 ± 0.023	1.063IleAsn: 1.063 ± 0.037	1.762IlePro: 1.762 ± 0.039	0.949IleGln: 0.949 ± 0.03	3.102IleArg: 3.102 ± 0.054	1.99IleSer: 1.99 ± 0.047	2.226IleThr: 2.226 ± 0.06	4.216IleVal: 4.216 ± 0.062	0.466IleTrp: 0.466 ± 0.021	0.853IleTyr: 0.853 ± 0.03	0.0IleXaa: 0.0 ± 0.0
Lys	3.67LysAla: 3.67 ± 0.068	0.109LysCys: 0.109 ± 0.009	1.207LysAsp: 1.207 ± 0.041	0.979LysGlu: 0.979 ± 0.037	0.617LysPhe: 0.617 ± 0.023	2.193LysGly: 2.193 ± 0.046	0.42LysHis: 0.42 ± 0.02	1.041LysIle: 1.041 ± 0.036	0.764LysLys: 0.764 ± 0.037	2.704LysLeu: 2.704 ± 0.053	0.572LysMet: 0.572 ± 0.024	0.489LysAsn: 0.489 ± 0.021	1.712LysPro: 1.712 ± 0.044	0.772LysGln: 0.772 ± 0.027	1.987LysArg: 1.987 ± 0.043	1.236LysSer: 1.236 ± 0.038	1.298LysThr: 1.298 ± 0.036	1.893LysVal: 1.893 ± 0.048	0.292LysTrp: 0.292 ± 0.016	0.447LysTyr: 0.447 ± 0.022	0.0LysXaa: 0.0 ± 0.0
Leu	16.02LeuAla: 16.02 ± 0.168	0.728LeuCys: 0.728 ± 0.024	6.543LeuAsp: 6.543 ± 0.077	4.481LeuGlu: 4.481 ± 0.072	3.625LeuPhe: 3.625 ± 0.063	8.783LeuGly: 8.783 ± 0.099	1.839LeuHis: 1.839 ± 0.044	4.577LeuIle: 4.577 ± 0.068	2.718LeuLys: 2.718 ± 0.055	10.308LeuLeu: 10.308 ± 0.135	1.991LeuMet: 1.991 ± 0.048	2.257LeuAsn: 2.257 ± 0.042	6.074LeuPro: 6.074 ± 0.08	2.25LeuGln: 2.25 ± 0.039	7.53LeuArg: 7.53 ± 0.083	5.657LeuSer: 5.657 ± 0.061	5.87LeuThr: 5.87 ± 0.09	7.687LeuVal: 7.687 ± 0.09	1.246LeuTrp: 1.246 ± 0.035	1.919LeuTyr: 1.919 ± 0.042	0.0LeuXaa: 0.0 ± 0.0
Met	3.168MetAla: 3.168 ± 0.058	0.146MetCys: 0.146 ± 0.01	0.991MetAsp: 0.991 ± 0.03	0.932MetGlu: 0.932 ± 0.029	0.589MetPhe: 0.589 ± 0.023	1.671MetGly: 1.671 ± 0.039	0.389MetHis: 0.389 ± 0.019	1.149MetIle: 1.149 ± 0.028	0.694MetLys: 0.694 ± 0.026	2.452MetLeu: 2.452 ± 0.052	0.556MetMet: 0.556 ± 0.023	0.555MetAsn: 0.555 ± 0.022	1.415MetPro: 1.415 ± 0.033	0.584MetGln: 0.584 ± 0.021	1.77MetArg: 1.77 ± 0.038	1.294MetSer: 1.294 ± 0.035	1.622MetThr: 1.622 ± 0.038	1.494MetVal: 1.494 ± 0.035	0.197MetTrp: 0.197 ± 0.015	0.244MetTyr: 0.244 ± 0.013	0.0MetXaa: 0.0 ± 0.0
Asn	2.953AsnAla: 2.953 ± 0.069	0.172AsnCys: 0.172 ± 0.012	1.19AsnAsp: 1.19 ± 0.043	0.968AsnGlu: 0.968 ± 0.027	0.733AsnPhe: 0.733 ± 0.026	2.153AsnGly: 2.153 ± 0.074	0.389AsnHis: 0.389 ± 0.018	1.033AsnIle: 1.033 ± 0.035	0.569AsnLys: 0.569 ± 0.022	2.261AsnLeu: 2.261 ± 0.05	0.452AsnMet: 0.452 ± 0.023	0.573AsnAsn: 0.573 ± 0.023	1.544AsnPro: 1.544 ± 0.038	0.623AsnGln: 0.623 ± 0.023	1.729AsnArg: 1.729 ± 0.038	1.004AsnSer: 1.004 ± 0.036	0.974AsnThr: 0.974 ± 0.037	1.744AsnVal: 1.744 ± 0.047	0.321AsnTrp: 0.321 ± 0.017	0.6AsnTyr: 0.6 ± 0.023	0.0AsnXaa: 0.0 ± 0.0
Pro	8.586ProAla: 8.586 ± 0.139	0.331ProCys: 0.331 ± 0.018	3.763ProAsp: 3.763 ± 0.07	3.423ProGlu: 3.423 ± 0.054	1.908ProPhe: 1.908 ± 0.043	5.167ProGly: 5.167 ± 0.067	1.038ProHis: 1.038 ± 0.031	2.22ProIle: 2.22 ± 0.038	1.35ProLys: 1.35 ± 0.035	5.455ProLeu: 5.455 ± 0.087	1.1ProMet: 1.1 ± 0.033	1.163ProAsn: 1.163 ± 0.034	3.165ProPro: 3.165 ± 0.075	1.642ProGln: 1.642 ± 0.04	3.501ProArg: 3.501 ± 0.058	2.622ProSer: 2.622 ± 0.048	2.688ProThr: 2.688 ± 0.054	4.405ProVal: 4.405 ± 0.067	0.698ProTrp: 0.698 ± 0.027	1.001ProTyr: 1.001 ± 0.026	0.0ProXaa: 0.0 ± 0.0
Gln	4.557GlnAla: 4.557 ± 0.063	0.169GlnCys: 0.169 ± 0.013	1.306GlnAsp: 1.306 ± 0.03	1.121GlnGlu: 1.121 ± 0.033	0.913GlnPhe: 0.913 ± 0.03	2.445GlnGly: 2.445 ± 0.046	0.551GlnHis: 0.551 ± 0.023	1.483GlnIle: 1.483 ± 0.04	0.72GlnLys: 0.72 ± 0.026	3.088GlnLeu: 3.088 ± 0.053	0.691GlnMet: 0.691 ± 0.024	0.604GlnAsn: 0.604 ± 0.023	1.87GlnPro: 1.87 ± 0.041	1.094GlnGln: 1.094 ± 0.035	2.449GlnArg: 2.449 ± 0.05	1.444GlnSer: 1.444 ± 0.038	1.616GlnThr: 1.616 ± 0.042	2.291GlnVal: 2.291 ± 0.047	0.319GlnTrp: 0.319 ± 0.014	0.508GlnTyr: 0.508 ± 0.022	0.0GlnXaa: 0.0 ± 0.0
Arg	10.53ArgAla: 10.53 ± 0.128	0.507ArgCys: 0.507 ± 0.021	4.655ArgAsp: 4.655 ± 0.071	4.115ArgGlu: 4.115 ± 0.066	3.381ArgPhe: 3.381 ± 0.062	5.917ArgGly: 5.917 ± 0.078	1.714ArgHis: 1.714 ± 0.041	4.171ArgIle: 4.171 ± 0.063	1.601ArgLys: 1.601 ± 0.043	9.471ArgLeu: 9.471 ± 0.132	2.068ArgMet: 2.068 ± 0.04	1.654ArgAsn: 1.654 ± 0.038	4.165ArgPro: 4.165 ± 0.06	2.438ArgGln: 2.438 ± 0.049	6.837ArgArg: 6.837 ± 0.1	3.657ArgSer: 3.657 ± 0.067	4.087ArgThr: 4.087 ± 0.061	5.55ArgVal: 5.55 ± 0.073	1.389ArgTrp: 1.389 ± 0.042	1.936ArgTyr: 1.936 ± 0.044	0.0ArgXaa: 0.0 ± 0.0
Ser	6.481SerAla: 6.481 ± 0.096	0.327SerCys: 0.327 ± 0.018	2.78SerAsp: 2.78 ± 0.044	2.214SerGlu: 2.214 ± 0.044	1.978SerPhe: 1.978 ± 0.041	5.26SerGly: 5.26 ± 0.101	0.796SerHis: 0.796 ± 0.025	2.263SerIle: 2.263 ± 0.047	1.065SerLys: 1.065 ± 0.034	4.838SerLeu: 4.838 ± 0.066	0.97SerMet: 0.97 ± 0.031	1.107SerAsn: 1.107 ± 0.038	2.703SerPro: 2.703 ± 0.058	1.226SerGln: 1.226 ± 0.034	3.274SerArg: 3.274 ± 0.06	2.321SerSer: 2.321 ± 0.053	2.438SerThr: 2.438 ± 0.052	3.529SerVal: 3.529 ± 0.064	0.747SerTrp: 0.747 ± 0.027	1.258SerTyr: 1.258 ± 0.04	0.0SerXaa: 0.0 ± 0.0
Thr	7.02ThrAla: 7.02 ± 0.149	0.364ThrCys: 0.364 ± 0.017	2.774ThrAsp: 2.774 ± 0.054	2.153ThrGlu: 2.153 ± 0.038	1.776ThrPhe: 1.776 ± 0.042	5.741ThrGly: 5.741 ± 0.135	0.913ThrHis: 0.913 ± 0.031	2.835ThrIle: 2.835 ± 0.061	1.155ThrLys: 1.155 ± 0.032	6.403ThrLeu: 6.403 ± 0.093	1.092ThrMet: 1.092 ± 0.029	1.202ThrAsn: 1.202 ± 0.041	3.634ThrPro: 3.634 ± 0.065	1.419ThrGln: 1.419 ± 0.041	3.754ThrArg: 3.754 ± 0.057	2.57ThrSer: 2.57 ± 0.058	2.793ThrThr: 2.793 ± 0.073	4.327ThrVal: 4.327 ± 0.113	0.64ThrTrp: 0.64 ± 0.023	1.142ThrTyr: 1.142 ± 0.033	0.0ThrXaa: 0.0 ± 0.0
Val	11.046ValAla: 11.046 ± 0.114	0.528ValCys: 0.528 ± 0.019	4.449ValAsp: 4.449 ± 0.062	4.625ValGlu: 4.625 ± 0.07	1.944ValPhe: 1.944 ± 0.041	5.941ValGly: 5.941 ± 0.072	1.293ValHis: 1.293 ± 0.033	3.301ValIle: 3.301 ± 0.059	1.667ValLys: 1.667 ± 0.041	6.872ValLeu: 6.872 ± 0.089	1.435ValMet: 1.435 ± 0.041	1.932ValAsn: 1.932 ± 0.055	4.343ValPro: 4.343 ± 0.069	2.127ValGln: 2.127 ± 0.043	5.921ValArg: 5.921 ± 0.083	3.935ValSer: 3.935 ± 0.064	4.741ValThr: 4.741 ± 0.094	5.354ValVal: 5.354 ± 0.084	0.855ValTrp: 0.855 ± 0.028	1.266ValTyr: 1.266 ± 0.031	0.0ValXaa: 0.0 ± 0.0
Trp	1.547TrpAla: 1.547 ± 0.04	0.122TrpCys: 0.122 ± 0.01	0.717TrpAsp: 0.717 ± 0.022	0.541TrpGlu: 0.541 ± 0.022	0.521TrpPhe: 0.521 ± 0.023	0.993TrpGly: 0.993 ± 0.033	0.331TrpHis: 0.331 ± 0.016	0.612TrpIle: 0.612 ± 0.025	0.362TrpLys: 0.362 ± 0.018	1.766TrpLeu: 1.766 ± 0.047	0.314TrpMet: 0.314 ± 0.015	0.358TrpAsn: 0.358 ± 0.018	0.744TrpPro: 0.744 ± 0.027	0.596TrpGln: 0.596 ± 0.026	1.501TrpArg: 1.501 ± 0.041	0.888TrpSer: 0.888 ± 0.031	0.873TrpThr: 0.873 ± 0.024	0.798TrpVal: 0.798 ± 0.025	0.266TrpTrp: 0.266 ± 0.015	0.274TrpTyr: 0.274 ± 0.014	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.775TyrAla: 2.775 ± 0.051	0.17TyrCys: 0.17 ± 0.013	1.46TyrAsp: 1.46 ± 0.04	1.026TyrGlu: 1.026 ± 0.03	0.716TyrPhe: 0.716 ± 0.028	2.048TyrGly: 2.048 ± 0.05	0.423TyrHis: 0.423 ± 0.018	0.706TyrIle: 0.706 ± 0.025	0.522TyrLys: 0.522 ± 0.023	2.03TyrLeu: 2.03 ± 0.045	0.353TyrMet: 0.353 ± 0.017	0.527TyrAsn: 0.527 ± 0.021	0.984TyrPro: 0.984 ± 0.029	0.62TyrGln: 0.62 ± 0.021	2.008TyrArg: 2.008 ± 0.047	1.034TyrSer: 1.034 ± 0.036	0.972TyrThr: 0.972 ± 0.035	1.545TyrVal: 1.545 ± 0.036	0.331TyrTrp: 0.331 ± 0.017	0.552TyrTyr: 0.552 ± 0.024	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 3810 proteins (1249194 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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