Amino acid dipepetide frequency for Felis catus papillomavirus 3

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
4.499AlaAla: 4.499 ± 1.527
2.25AlaCys: 2.25 ± 1.517
4.124AlaAsp: 4.124 ± 0.641
4.499AlaGlu: 4.499 ± 1.712
2.625AlaPhe: 2.625 ± 0.775
3.75AlaGly: 3.75 ± 0.982
1.125AlaHis: 1.125 ± 0.473
1.5AlaIle: 1.5 ± 0.73
3.0AlaLys: 3.0 ± 1.059
5.624AlaLeu: 5.624 ± 1.654
1.5AlaMet: 1.5 ± 0.835
2.25AlaAsn: 2.25 ± 0.781
2.25AlaPro: 2.25 ± 0.881
2.625AlaGln: 2.625 ± 0.467
3.0AlaArg: 3.0 ± 0.761
4.124AlaSer: 4.124 ± 1.272
3.0AlaThr: 3.0 ± 0.603
1.5AlaVal: 1.5 ± 1.035
0.375AlaTrp: 0.375 ± 0.324
2.625AlaTyr: 2.625 ± 0.902
0.0AlaXaa: 0.0 ± 0.0
Cys
2.625CysAla: 2.625 ± 1.329
3.0CysCys: 3.0 ± 2.247
1.5CysAsp: 1.5 ± 0.568
0.375CysGlu: 0.375 ± 0.484
2.625CysPhe: 2.625 ± 1.164
1.5CysGly: 1.5 ± 1.232
0.0CysHis: 0.0 ± 0.0
1.5CysIle: 1.5 ± 0.691
2.25CysLys: 2.25 ± 0.65
1.875CysLeu: 1.875 ± 0.932
0.0CysMet: 0.0 ± 0.0
0.75CysAsn: 0.75 ± 0.717
1.5CysPro: 1.5 ± 0.836
0.375CysGln: 0.375 ± 0.324
1.875CysArg: 1.875 ± 0.843
1.125CysSer: 1.125 ± 0.621
1.5CysThr: 1.5 ± 1.035
1.5CysVal: 1.5 ± 0.783
0.75CysTrp: 0.75 ± 0.363
0.375CysTyr: 0.375 ± 0.359
0.0CysXaa: 0.0 ± 0.0
Asp
3.375AspAla: 3.375 ± 0.863
3.375AspCys: 3.375 ± 1.22
1.875AspAsp: 1.875 ± 0.964
4.124AspGlu: 4.124 ± 0.921
2.25AspPhe: 2.25 ± 0.874
4.124AspGly: 4.124 ± 0.885
0.75AspHis: 0.75 ± 0.717
3.375AspIle: 3.375 ± 1.09
4.124AspLys: 4.124 ± 0.641
5.249AspLeu: 5.249 ± 1.96
0.0AspMet: 0.0 ± 0.0
1.5AspAsn: 1.5 ± 0.561
3.75AspPro: 3.75 ± 1.348
1.5AspGln: 1.5 ± 0.568
1.875AspArg: 1.875 ± 0.595
5.249AspSer: 5.249 ± 0.67
2.25AspThr: 2.25 ± 0.861
3.75AspVal: 3.75 ± 1.328
1.125AspTrp: 1.125 ± 0.64
1.125AspTyr: 1.125 ± 0.581
0.0AspXaa: 0.0 ± 0.0
Glu
4.124GluAla: 4.124 ± 1.17
1.125GluCys: 1.125 ± 0.565
5.624GluAsp: 5.624 ± 1.414
10.499GluGlu: 10.499 ± 6.69
0.375GluPhe: 0.375 ± 0.318
4.874GluGly: 4.874 ± 1.225
1.5GluHis: 1.5 ± 0.564
3.375GluIle: 3.375 ± 0.924
3.75GluLys: 3.75 ± 1.543
5.249GluLeu: 5.249 ± 1.685
0.375GluMet: 0.375 ± 0.324
1.875GluAsn: 1.875 ± 0.724
2.625GluPro: 2.625 ± 1.026
2.25GluGln: 2.25 ± 0.706
3.375GluArg: 3.375 ± 1.095
3.75GluSer: 3.75 ± 1.297
5.249GluThr: 5.249 ± 0.987
4.124GluVal: 4.124 ± 0.689
1.125GluTrp: 1.125 ± 0.663
0.75GluTyr: 0.75 ± 0.569
0.0GluXaa: 0.0 ± 0.0
Phe
3.0PheAla: 3.0 ± 1.538
1.125PheCys: 1.125 ± 0.565
2.25PheAsp: 2.25 ± 0.616
1.875PheGlu: 1.875 ± 0.931
3.375PhePhe: 3.375 ± 1.123
1.875PheGly: 1.875 ± 0.793
0.375PheHis: 0.375 ± 0.324
2.25PheIle: 2.25 ± 0.739
2.625PheLys: 2.625 ± 1.151
4.499PheLeu: 4.499 ± 0.968
0.75PheMet: 0.75 ± 0.648
0.75PheAsn: 0.75 ± 0.375
3.375PhePro: 3.375 ± 0.648
1.5PheGln: 1.5 ± 0.407
0.75PheArg: 0.75 ± 0.522
1.875PheSer: 1.875 ± 0.683
4.124PheThr: 4.124 ± 1.346
1.875PheVal: 1.875 ± 0.566
1.125PheTrp: 1.125 ± 0.581
1.875PheTyr: 1.875 ± 0.548
0.0PheXaa: 0.0 ± 0.0
Gly
4.499GlyAla: 4.499 ± 1.078
1.5GlyCys: 1.5 ± 0.899
5.249GlyAsp: 5.249 ± 1.493
4.874GlyGlu: 4.874 ± 0.843
2.25GlyPhe: 2.25 ± 0.737
9.749GlyGly: 9.749 ± 2.979
0.75GlyHis: 0.75 ± 0.499
4.874GlyIle: 4.874 ± 0.779
4.124GlyLys: 4.124 ± 1.145
4.874GlyLeu: 4.874 ± 0.823
2.25GlyMet: 2.25 ± 0.726
2.625GlyAsn: 2.625 ± 0.742
6.374GlyPro: 6.374 ± 1.864
3.375GlyGln: 3.375 ± 0.956
7.874GlyArg: 7.874 ± 3.306
6.374GlySer: 6.374 ± 1.364
5.999GlyThr: 5.999 ± 2.414
3.75GlyVal: 3.75 ± 1.406
0.75GlyTrp: 0.75 ± 0.423
1.125GlyTyr: 1.125 ± 0.396
0.0GlyXaa: 0.0 ± 0.0
His
0.375HisAla: 0.375 ± 0.324
0.75HisCys: 0.75 ± 0.355
0.75HisAsp: 0.75 ± 0.534
0.75HisGlu: 0.75 ± 0.423
1.5HisPhe: 1.5 ± 0.271
1.125HisGly: 1.125 ± 0.579
0.0HisHis: 0.0 ± 0.0
0.75HisIle: 0.75 ± 0.387
0.375HisLys: 0.375 ± 0.468
1.5HisLeu: 1.5 ± 1.049
0.0HisMet: 0.0 ± 0.0
0.375HisAsn: 0.375 ± 0.299
2.625HisPro: 2.625 ± 1.15
0.75HisGln: 0.75 ± 0.648
1.125HisArg: 1.125 ± 0.581
1.5HisSer: 1.5 ± 0.699
0.75HisThr: 0.75 ± 0.418
0.375HisVal: 0.375 ± 0.318
0.375HisTrp: 0.375 ± 0.285
0.375HisTyr: 0.375 ± 0.324
0.0HisXaa: 0.0 ± 0.0
Ile
1.5IleAla: 1.5 ± 0.821
1.125IleCys: 1.125 ± 1.002
3.75IleAsp: 3.75 ± 1.138
3.75IleGlu: 3.75 ± 0.657
1.125IlePhe: 1.125 ± 0.309
4.124IleGly: 4.124 ± 1.323
0.0IleHis: 0.0 ± 0.0
0.75IleIle: 0.75 ± 0.518
0.75IleLys: 0.75 ± 0.423
5.624IleLeu: 5.624 ± 2.141
0.375IleMet: 0.375 ± 0.324
1.5IleAsn: 1.5 ± 0.69
2.25IlePro: 2.25 ± 0.914
1.125IleGln: 1.125 ± 0.625
1.875IleArg: 1.875 ± 0.669
2.625IleSer: 2.625 ± 1.196
0.75IleThr: 0.75 ± 0.355
4.124IleVal: 4.124 ± 1.118
0.0IleTrp: 0.0 ± 0.0
2.625IleTyr: 2.625 ± 0.873
0.0IleXaa: 0.0 ± 0.0
Lys
2.25LysAla: 2.25 ± 0.962
0.75LysCys: 0.75 ± 0.363
3.0LysAsp: 3.0 ± 0.737
3.0LysGlu: 3.0 ± 0.48
2.25LysPhe: 2.25 ± 0.777
4.499LysGly: 4.499 ± 1.126
1.875LysHis: 1.875 ± 0.592
0.75LysIle: 0.75 ± 0.548
2.25LysLys: 2.25 ± 0.977
3.0LysLeu: 3.0 ± 0.949
0.75LysMet: 0.75 ± 0.648
0.75LysAsn: 0.75 ± 0.375
4.874LysPro: 4.874 ± 1.333
2.625LysGln: 2.625 ± 0.844
3.75LysArg: 3.75 ± 1.391
3.75LysSer: 3.75 ± 1.997
3.0LysThr: 3.0 ± 0.723
2.625LysVal: 2.625 ± 0.991
1.125LysTrp: 1.125 ± 0.545
2.25LysTyr: 2.25 ± 1.152
0.0LysXaa: 0.0 ± 0.0
Leu
3.75LeuAla: 3.75 ± 1.029
1.875LeuCys: 1.875 ± 0.933
4.124LeuAsp: 4.124 ± 1.319
4.499LeuGlu: 4.499 ± 0.876
4.499LeuPhe: 4.499 ± 1.606
8.624LeuGly: 8.624 ± 2.429
1.125LeuHis: 1.125 ± 0.616
1.875LeuIle: 1.875 ± 0.81
4.124LeuLys: 4.124 ± 1.272
7.124LeuLeu: 7.124 ± 1.747
3.375LeuMet: 3.375 ± 1.253
1.125LeuAsn: 1.125 ± 0.744
3.75LeuPro: 3.75 ± 0.683
8.249LeuGln: 8.249 ± 1.276
4.499LeuArg: 4.499 ± 0.707
6.749LeuSer: 6.749 ± 1.196
5.249LeuThr: 5.249 ± 1.052
7.499LeuVal: 7.499 ± 1.139
1.875LeuTrp: 1.875 ± 0.635
4.874LeuTyr: 4.874 ± 1.069
0.0LeuXaa: 0.0 ± 0.0
Met
1.5MetAla: 1.5 ± 0.607
1.125MetCys: 1.125 ± 0.473
0.0MetAsp: 0.0 ± 0.0
0.75MetGlu: 0.75 ± 0.381
1.125MetPhe: 1.125 ± 0.854
0.375MetGly: 0.375 ± 0.324
0.0MetHis: 0.0 ± 0.0
0.375MetIle: 0.375 ± 0.299
0.0MetLys: 0.0 ± 0.0
2.25MetLeu: 2.25 ± 0.908
0.0MetMet: 0.0 ± 0.0
1.875MetAsn: 1.875 ± 0.936
1.125MetPro: 1.125 ± 0.517
0.375MetGln: 0.375 ± 0.324
3.375MetArg: 3.375 ± 1.57
0.375MetSer: 0.375 ± 0.285
1.5MetThr: 1.5 ± 0.772
1.5MetVal: 1.5 ± 0.614
0.375MetTrp: 0.375 ± 0.318
0.375MetTyr: 0.375 ± 0.359
0.0MetXaa: 0.0 ± 0.0
Asn
3.75AsnAla: 3.75 ± 1.65
1.125AsnCys: 1.125 ± 0.437
0.375AsnAsp: 0.375 ± 0.285
1.875AsnGlu: 1.875 ± 0.876
2.625AsnPhe: 2.625 ± 1.302
1.5AsnGly: 1.5 ± 0.891
0.375AsnHis: 0.375 ± 0.299
1.5AsnIle: 1.5 ± 0.628
3.0AsnLys: 3.0 ± 0.822
3.375AsnLeu: 3.375 ± 0.741
0.75AsnMet: 0.75 ± 0.391
0.75AsnAsn: 0.75 ± 0.387
4.124AsnPro: 4.124 ± 1.032
0.75AsnGln: 0.75 ± 0.569
1.5AsnArg: 1.5 ± 0.537
1.875AsnSer: 1.875 ± 0.959
2.25AsnThr: 2.25 ± 1.141
1.875AsnVal: 1.875 ± 0.662
0.0AsnTrp: 0.0 ± 0.0
0.75AsnTyr: 0.75 ± 0.569
0.0AsnXaa: 0.0 ± 0.0
Pro
3.375ProAla: 3.375 ± 0.923
1.125ProCys: 1.125 ± 0.689
4.499ProAsp: 4.499 ± 0.814
3.375ProGlu: 3.375 ± 0.574
3.0ProPhe: 3.0 ± 1.111
3.75ProGly: 3.75 ± 1.414
0.375ProHis: 0.375 ± 0.318
2.625ProIle: 2.625 ± 1.09
4.499ProLys: 4.499 ± 1.289
6.749ProLeu: 6.749 ± 1.722
1.125ProMet: 1.125 ± 0.622
2.625ProAsn: 2.625 ± 0.99
8.624ProPro: 8.624 ± 3.549
3.375ProGln: 3.375 ± 1.092
5.999ProArg: 5.999 ± 2.035
5.999ProSer: 5.999 ± 1.113
3.75ProThr: 3.75 ± 1.419
4.124ProVal: 4.124 ± 1.014
0.75ProTrp: 0.75 ± 0.451
1.5ProTyr: 1.5 ± 0.585
0.0ProXaa: 0.0 ± 0.0
Gln
3.75GlnAla: 3.75 ± 1.436
0.375GlnCys: 0.375 ± 0.483
2.625GlnAsp: 2.625 ± 1.226
3.75GlnGlu: 3.75 ± 1.03
1.5GlnPhe: 1.5 ± 0.407
3.75GlnGly: 3.75 ± 1.412
1.125GlnHis: 1.125 ± 0.736
2.625GlnIle: 2.625 ± 1.229
0.75GlnLys: 0.75 ± 0.569
3.75GlnLeu: 3.75 ± 1.269
2.25GlnMet: 2.25 ± 0.825
3.375GlnAsn: 3.375 ± 1.12
1.875GlnPro: 1.875 ± 0.635
3.75GlnGln: 3.75 ± 1.469
2.25GlnArg: 2.25 ± 0.747
2.25GlnSer: 2.25 ± 0.511
2.625GlnThr: 2.625 ± 0.767
3.75GlnVal: 3.75 ± 0.956
1.5GlnTrp: 1.5 ± 0.618
1.125GlnTyr: 1.125 ± 0.601
0.0GlnXaa: 0.0 ± 0.0
Arg
2.625ArgAla: 2.625 ± 0.923
1.125ArgCys: 1.125 ± 0.625
2.625ArgAsp: 2.625 ± 0.815
2.25ArgGlu: 2.25 ± 0.63
1.125ArgPhe: 1.125 ± 0.581
8.624ArgGly: 8.624 ± 3.736
1.875ArgHis: 1.875 ± 0.639
0.75ArgIle: 0.75 ± 0.538
3.75ArgLys: 3.75 ± 0.849
7.124ArgLeu: 7.124 ± 0.7
0.75ArgMet: 0.75 ± 0.434
1.875ArgAsn: 1.875 ± 0.964
2.625ArgPro: 2.625 ± 0.527
3.75ArgGln: 3.75 ± 0.563
6.374ArgArg: 6.374 ± 2.523
4.124ArgSer: 4.124 ± 0.882
3.375ArgThr: 3.375 ± 0.667
4.874ArgVal: 4.874 ± 0.808
0.75ArgTrp: 0.75 ± 0.548
2.25ArgTyr: 2.25 ± 0.503
0.0ArgXaa: 0.0 ± 0.0
Ser
2.625SerAla: 2.625 ± 1.113
1.125SerCys: 1.125 ± 0.424
3.375SerAsp: 3.375 ± 0.972
4.874SerGlu: 4.874 ± 1.057
3.75SerPhe: 3.75 ± 0.972
5.624SerGly: 5.624 ± 1.151
1.5SerHis: 1.5 ± 0.614
3.75SerIle: 3.75 ± 0.967
4.124SerLys: 4.124 ± 1.515
6.374SerLeu: 6.374 ± 0.973
0.75SerMet: 0.75 ± 0.365
3.0SerAsn: 3.0 ± 1.299
5.249SerPro: 5.249 ± 1.603
4.124SerGln: 4.124 ± 1.099
2.625SerArg: 2.625 ± 0.74
8.624SerSer: 8.624 ± 1.355
7.874SerThr: 7.874 ± 2.908
4.874SerVal: 4.874 ± 1.343
0.75SerTrp: 0.75 ± 0.363
1.125SerTyr: 1.125 ± 0.437
0.0SerXaa: 0.0 ± 0.0
Thr
3.375ThrAla: 3.375 ± 0.647
1.5ThrCys: 1.5 ± 0.699
3.0ThrAsp: 3.0 ± 0.495
5.249ThrGlu: 5.249 ± 0.963
1.875ThrPhe: 1.875 ± 0.92
7.124ThrGly: 7.124 ± 2.203
1.875ThrHis: 1.875 ± 0.921
3.0ThrIle: 3.0 ± 0.775
1.875ThrLys: 1.875 ± 0.673
3.75ThrLeu: 3.75 ± 0.818
0.375ThrMet: 0.375 ± 0.324
1.5ThrAsn: 1.5 ± 0.407
6.374ThrPro: 6.374 ± 1.452
2.625ThrGln: 2.625 ± 0.598
3.0ThrArg: 3.0 ± 1.176
5.999ThrSer: 5.999 ± 1.464
3.0ThrThr: 3.0 ± 0.678
3.75ThrVal: 3.75 ± 0.943
0.0ThrTrp: 0.0 ± 0.0
1.5ThrTyr: 1.5 ± 0.564
0.0ThrXaa: 0.0 ± 0.0
Val
1.5ValAla: 1.5 ± 0.783
1.875ValCys: 1.875 ± 1.336
3.75ValAsp: 3.75 ± 0.94
3.0ValGlu: 3.0 ± 0.858
2.25ValPhe: 2.25 ± 0.739
5.249ValGly: 5.249 ± 2.444
0.75ValHis: 0.75 ± 0.451
2.25ValIle: 2.25 ± 0.825
2.625ValLys: 2.625 ± 0.719
5.249ValLeu: 5.249 ± 0.925
1.5ValMet: 1.5 ± 0.585
3.0ValAsn: 3.0 ± 1.459
5.624ValPro: 5.624 ± 1.299
3.375ValGln: 3.375 ± 0.949
3.75ValArg: 3.75 ± 1.702
7.124ValSer: 7.124 ± 1.126
3.375ValThr: 3.375 ± 1.018
3.75ValVal: 3.75 ± 0.848
1.125ValTrp: 1.125 ± 0.638
0.75ValTyr: 0.75 ± 0.648
0.0ValXaa: 0.0 ± 0.0
Trp
1.5TrpAla: 1.5 ± 0.725
0.0TrpCys: 0.0 ± 0.0
1.125TrpAsp: 1.125 ± 0.396
0.75TrpGlu: 0.75 ± 0.598
0.375TrpPhe: 0.375 ± 0.299
1.125TrpGly: 1.125 ± 0.515
0.0TrpHis: 0.0 ± 0.0
0.75TrpIle: 0.75 ± 0.363
0.375TrpLys: 0.375 ± 0.324
2.25TrpLeu: 2.25 ± 0.826
0.75TrpMet: 0.75 ± 0.621
0.375TrpAsn: 0.375 ± 0.285
0.375TrpPro: 0.375 ± 0.285
0.375TrpGln: 0.375 ± 0.285
1.875TrpArg: 1.875 ± 0.801
1.125TrpSer: 1.125 ± 0.581
0.0TrpThr: 0.0 ± 0.0
1.125TrpVal: 1.125 ± 0.424
0.0TrpTrp: 0.0 ± 0.0
0.375TrpTyr: 0.375 ± 0.324
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.25TyrAla: 2.25 ± 0.409
0.75TyrCys: 0.75 ± 0.381
1.125TyrAsp: 1.125 ± 0.621
1.875TyrGlu: 1.875 ± 0.707
0.75TyrPhe: 0.75 ± 0.355
1.875TyrGly: 1.875 ± 0.936
0.75TyrHis: 0.75 ± 0.418
1.125TyrIle: 1.125 ± 0.758
0.75TyrLys: 0.75 ± 0.355
3.75TyrLeu: 3.75 ± 1.652
0.375TyrMet: 0.375 ± 0.324
2.25TyrAsn: 2.25 ± 1.402
1.875TyrPro: 1.875 ± 0.669
1.875TyrGln: 1.875 ± 0.443
1.875TyrArg: 1.875 ± 0.637
1.5TyrSer: 1.5 ± 0.954
1.125TyrThr: 1.125 ± 0.309
1.125TyrVal: 1.125 ± 0.359
0.75TyrTrp: 0.75 ± 0.381
1.5TyrTyr: 1.5 ± 0.762
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 8 proteins (2668 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski