Amino acid dipepetide frequency for Pulveribacter suum

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	22.271AlaAla: 22.271 ± 0.245	1.479AlaCys: 1.479 ± 0.043	6.248AlaAsp: 6.248 ± 0.081	6.789AlaGlu: 6.789 ± 0.103	3.978AlaPhe: 3.978 ± 0.059	12.521AlaGly: 12.521 ± 0.138	3.208AlaHis: 3.208 ± 0.063	4.779AlaIle: 4.779 ± 0.073	3.133AlaLys: 3.133 ± 0.077	17.704AlaLeu: 17.704 ± 0.19	3.483AlaMet: 3.483 ± 0.056	2.385AlaAsn: 2.385 ± 0.06	8.144AlaPro: 8.144 ± 0.137	7.832AlaGln: 7.832 ± 0.113	11.139AlaArg: 11.139 ± 0.121	6.973AlaSer: 6.973 ± 0.105	6.242AlaThr: 6.242 ± 0.078	9.511AlaVal: 9.511 ± 0.112	2.25AlaTrp: 2.25 ± 0.062	2.315AlaTyr: 2.315 ± 0.046	0.0AlaXaa: 0.0 ± 0.0
Cys	1.27CysAla: 1.27 ± 0.033	0.11CysCys: 0.11 ± 0.012	0.502CysAsp: 0.502 ± 0.024	0.52CysGlu: 0.52 ± 0.022	0.294CysPhe: 0.294 ± 0.016	0.953CysGly: 0.953 ± 0.037	0.29CysHis: 0.29 ± 0.017	0.393CysIle: 0.393 ± 0.022	0.188CysLys: 0.188 ± 0.013	0.908CysLeu: 0.908 ± 0.026	0.232CysMet: 0.232 ± 0.015	0.215CysAsn: 0.215 ± 0.014	0.529CysPro: 0.529 ± 0.026	0.326CysGln: 0.326 ± 0.019	0.524CysArg: 0.524 ± 0.021	0.492CysSer: 0.492 ± 0.025	0.493CysThr: 0.493 ± 0.023	0.744CysVal: 0.744 ± 0.027	0.121CysTrp: 0.121 ± 0.011	0.175CysTyr: 0.175 ± 0.014	0.0CysXaa: 0.0 ± 0.0
Asp	7.363AspAla: 7.363 ± 0.094	0.433AspCys: 0.433 ± 0.022	2.355AspAsp: 2.355 ± 0.06	3.167AspGlu: 3.167 ± 0.064	1.85AspPhe: 1.85 ± 0.042	4.401AspGly: 4.401 ± 0.07	0.987AspHis: 0.987 ± 0.034	2.11AspIle: 2.11 ± 0.054	1.595AspLys: 1.595 ± 0.046	4.842AspLeu: 4.842 ± 0.075	1.189AspMet: 1.189 ± 0.033	1.088AspAsn: 1.088 ± 0.035	2.587AspPro: 2.587 ± 0.055	1.469AspGln: 1.469 ± 0.037	2.795AspArg: 2.795 ± 0.053	2.047AspSer: 2.047 ± 0.045	2.311AspThr: 2.311 ± 0.052	3.946AspVal: 3.946 ± 0.066	0.989AspTrp: 0.989 ± 0.029	1.259AspTyr: 1.259 ± 0.037	0.0AspXaa: 0.0 ± 0.0
Glu	6.722GluAla: 6.722 ± 0.091	0.413GluCys: 0.413 ± 0.022	2.338GluAsp: 2.338 ± 0.05	2.499GluGlu: 2.499 ± 0.06	1.57GluPhe: 1.57 ± 0.041	4.234GluGly: 4.234 ± 0.068	1.409GluHis: 1.409 ± 0.037	2.27GluIle: 2.27 ± 0.055	1.51GluLys: 1.51 ± 0.049	5.921GluLeu: 5.921 ± 0.093	1.103GluMet: 1.103 ± 0.038	1.014GluAsn: 1.014 ± 0.033	2.622GluPro: 2.622 ± 0.056	3.017GluGln: 3.017 ± 0.061	5.109GluArg: 5.109 ± 0.082	2.086GluSer: 2.086 ± 0.053	2.055GluThr: 2.055 ± 0.047	4.024GluVal: 4.024 ± 0.069	0.627GluTrp: 0.627 ± 0.028	0.996GluTyr: 0.996 ± 0.033	0.0GluXaa: 0.0 ± 0.0
Phe	4.368PheAla: 4.368 ± 0.072	0.357PheCys: 0.357 ± 0.02	2.189PheAsp: 2.189 ± 0.053	1.867PheGlu: 1.867 ± 0.043	1.243PhePhe: 1.243 ± 0.045	3.156PheGly: 3.156 ± 0.062	0.655PheHis: 0.655 ± 0.028	1.454PheIle: 1.454 ± 0.048	0.983PheLys: 0.983 ± 0.032	2.685PheLeu: 2.685 ± 0.057	0.76PheMet: 0.76 ± 0.032	0.907PheAsn: 0.907 ± 0.036	1.32PhePro: 1.32 ± 0.037	0.996PheGln: 0.996 ± 0.034	1.646PheArg: 1.646 ± 0.04	1.863PheSer: 1.863 ± 0.045	1.859PheThr: 1.859 ± 0.05	2.577PheVal: 2.577 ± 0.052	0.504PheTrp: 0.504 ± 0.024	0.774PheTyr: 0.774 ± 0.031	0.0PheXaa: 0.0 ± 0.0
Gly	11.09GlyAla: 11.09 ± 0.126	0.986GlyCys: 0.986 ± 0.033	3.915GlyAsp: 3.915 ± 0.064	4.715GlyGlu: 4.715 ± 0.074	3.066GlyPhe: 3.066 ± 0.059	7.75GlyGly: 7.75 ± 0.137	2.013GlyHis: 2.013 ± 0.046	3.494GlyIle: 3.494 ± 0.064	2.766GlyLys: 2.766 ± 0.061	9.27GlyLeu: 9.27 ± 0.111	2.458GlyMet: 2.458 ± 0.053	1.961GlyAsn: 1.961 ± 0.057	3.251GlyPro: 3.251 ± 0.057	4.078GlyGln: 4.078 ± 0.068	6.076GlyArg: 6.076 ± 0.091	4.595GlySer: 4.595 ± 0.077	4.406GlyThr: 4.406 ± 0.074	6.843GlyVal: 6.843 ± 0.093	1.547GlyTrp: 1.547 ± 0.04	2.202GlyTyr: 2.202 ± 0.052	0.0GlyXaa: 0.0 ± 0.0
His	3.242HisAla: 3.242 ± 0.071	0.298HisCys: 0.298 ± 0.014	1.26HisAsp: 1.26 ± 0.036	1.321HisGlu: 1.321 ± 0.04	0.895HisPhe: 0.895 ± 0.03	2.278HisGly: 2.278 ± 0.051	0.632HisHis: 0.632 ± 0.026	0.935HisIle: 0.935 ± 0.029	0.538HisLys: 0.538 ± 0.025	2.388HisLeu: 2.388 ± 0.05	0.496HisMet: 0.496 ± 0.021	0.512HisAsn: 0.512 ± 0.025	1.6HisPro: 1.6 ± 0.043	0.895HisGln: 0.895 ± 0.031	1.425HisArg: 1.425 ± 0.035	1.029HisSer: 1.029 ± 0.032	1.145HisThr: 1.145 ± 0.032	1.668HisVal: 1.668 ± 0.037	0.437HisTrp: 0.437 ± 0.02	0.68HisTyr: 0.68 ± 0.027	0.0HisXaa: 0.0 ± 0.0
Ile	5.806IleAla: 5.806 ± 0.094	0.316IleCys: 0.316 ± 0.017	2.644IleAsp: 2.644 ± 0.047	2.71IleGlu: 2.71 ± 0.063	1.081IlePhe: 1.081 ± 0.037	3.555IleGly: 3.555 ± 0.07	0.782IleHis: 0.782 ± 0.028	1.356IleIle: 1.356 ± 0.042	1.218IleLys: 1.218 ± 0.04	2.929IleLeu: 2.929 ± 0.062	0.699IleMet: 0.699 ± 0.029	1.196IleAsn: 1.196 ± 0.032	1.647IlePro: 1.647 ± 0.043	1.151IleGln: 1.151 ± 0.037	2.304IleArg: 2.304 ± 0.048	1.863IleSer: 1.863 ± 0.045	2.323IleThr: 2.323 ± 0.046	3.253IleVal: 3.253 ± 0.065	0.404IleTrp: 0.404 ± 0.021	0.869IleTyr: 0.869 ± 0.028	0.0IleXaa: 0.0 ± 0.0
Lys	3.343LysAla: 3.343 ± 0.075	0.142LysCys: 0.142 ± 0.013	1.418LysAsp: 1.418 ± 0.046	1.309LysGlu: 1.309 ± 0.047	0.741LysPhe: 0.741 ± 0.032	2.149LysGly: 2.149 ± 0.047	0.499LysHis: 0.499 ± 0.021	1.177LysIle: 1.177 ± 0.04	1.23LysLys: 1.23 ± 0.048	2.715LysLeu: 2.715 ± 0.062	0.714LysMet: 0.714 ± 0.033	0.832LysAsn: 0.832 ± 0.031	1.585LysPro: 1.585 ± 0.044	0.953LysGln: 0.953 ± 0.029	1.779LysArg: 1.779 ± 0.051	1.482LysSer: 1.482 ± 0.042	1.608LysThr: 1.608 ± 0.045	2.06LysVal: 2.06 ± 0.068	0.262LysTrp: 0.262 ± 0.016	0.557LysTyr: 0.557 ± 0.028	0.0LysXaa: 0.0 ± 0.0
Leu	18.196LeuAla: 18.196 ± 0.209	1.063LeuCys: 1.063 ± 0.035	5.477LeuAsp: 5.477 ± 0.072	4.92LeuGlu: 4.92 ± 0.076	3.201LeuPhe: 3.201 ± 0.066	8.976LeuGly: 8.976 ± 0.107	2.809LeuHis: 2.809 ± 0.059	3.863LeuIle: 3.863 ± 0.068	2.99LeuLys: 2.99 ± 0.069	12.486LeuLeu: 12.486 ± 0.176	2.47LeuMet: 2.47 ± 0.051	2.278LeuAsn: 2.278 ± 0.049	6.847LeuPro: 6.847 ± 0.087	5.488LeuGln: 5.488 ± 0.087	8.25LeuArg: 8.25 ± 0.108	5.651LeuSer: 5.651 ± 0.088	5.181LeuThr: 5.181 ± 0.079	8.226LeuVal: 8.226 ± 0.116	1.484LeuTrp: 1.484 ± 0.052	2.066LeuTyr: 2.066 ± 0.042	0.0LeuXaa: 0.0 ± 0.0
Met	3.231MetAla: 3.231 ± 0.049	0.149MetCys: 0.149 ± 0.013	1.117MetAsp: 1.117 ± 0.032	1.067MetGlu: 1.067 ± 0.031	0.595MetPhe: 0.595 ± 0.023	2.035MetGly: 2.035 ± 0.052	0.593MetHis: 0.593 ± 0.028	0.757MetIle: 0.757 ± 0.032	0.86MetLys: 0.86 ± 0.03	2.468MetLeu: 2.468 ± 0.056	0.47MetMet: 0.47 ± 0.023	0.772MetAsn: 0.772 ± 0.029	1.472MetPro: 1.472 ± 0.034	1.313MetGln: 1.313 ± 0.038	1.638MetArg: 1.638 ± 0.037	1.336MetSer: 1.336 ± 0.037	1.433MetThr: 1.433 ± 0.038	1.671MetVal: 1.671 ± 0.05	0.182MetTrp: 0.182 ± 0.014	0.395MetTyr: 0.395 ± 0.021	0.0MetXaa: 0.0 ± 0.0
Asn	2.963AsnAla: 2.963 ± 0.06	0.213AsnCys: 0.213 ± 0.015	1.08AsnAsp: 1.08 ± 0.034	0.971AsnGlu: 0.971 ± 0.036	0.785AsnPhe: 0.785 ± 0.032	1.745AsnGly: 1.745 ± 0.044	0.458AsnHis: 0.458 ± 0.021	0.954AsnIle: 0.954 ± 0.032	0.624AsnLys: 0.624 ± 0.028	2.308AsnLeu: 2.308 ± 0.054	0.515AsnMet: 0.515 ± 0.023	0.609AsnAsn: 0.609 ± 0.029	1.606AsnPro: 1.606 ± 0.042	0.872AsnGln: 0.872 ± 0.034	1.404AsnArg: 1.404 ± 0.041	0.941AsnSer: 0.941 ± 0.035	1.16AsnThr: 1.16 ± 0.043	1.806AsnVal: 1.806 ± 0.049	0.346AsnTrp: 0.346 ± 0.019	0.573AsnTyr: 0.573 ± 0.024	0.0AsnXaa: 0.0 ± 0.0
Pro	8.832ProAla: 8.832 ± 0.131	0.381ProCys: 0.381 ± 0.021	2.832ProAsp: 2.832 ± 0.062	3.433ProGlu: 3.433 ± 0.067	1.695ProPhe: 1.695 ± 0.043	5.186ProGly: 5.186 ± 0.084	1.273ProHis: 1.273 ± 0.032	1.6ProIle: 1.6 ± 0.042	1.181ProLys: 1.181 ± 0.041	6.18ProLeu: 6.18 ± 0.093	1.213ProMet: 1.213 ± 0.033	0.94ProAsn: 0.94 ± 0.03	3.3ProPro: 3.3 ± 0.085	2.789ProGln: 2.789 ± 0.055	3.384ProArg: 3.384 ± 0.065	2.43ProSer: 2.43 ± 0.058	2.302ProThr: 2.302 ± 0.05	4.184ProVal: 4.184 ± 0.065	0.915ProTrp: 0.915 ± 0.032	1.105ProTyr: 1.105 ± 0.036	0.0ProXaa: 0.0 ± 0.0
Gln	7.521GlnAla: 7.521 ± 0.116	0.325GlnCys: 0.325 ± 0.016	2.202GlnAsp: 2.202 ± 0.052	1.978GlnGlu: 1.978 ± 0.05	1.331GlnPhe: 1.331 ± 0.041	3.977GlnGly: 3.977 ± 0.073	1.145GlnHis: 1.145 ± 0.035	1.675GlnIle: 1.675 ± 0.046	0.988GlnLys: 0.988 ± 0.035	5.619GlnLeu: 5.619 ± 0.077	1.015GlnMet: 1.015 ± 0.029	0.763GlnAsn: 0.763 ± 0.027	2.907GlnPro: 2.907 ± 0.061	2.74GlnGln: 2.74 ± 0.066	4.004GlnArg: 4.004 ± 0.075	2.03GlnSer: 2.03 ± 0.043	1.82GlnThr: 1.82 ± 0.045	3.591GlnVal: 3.591 ± 0.068	0.857GlnTrp: 0.857 ± 0.03	0.805GlnTyr: 0.805 ± 0.03	0.0GlnXaa: 0.0 ± 0.0
Arg	9.462ArgAla: 9.462 ± 0.12	0.609ArgCys: 0.609 ± 0.024	3.268ArgAsp: 3.268 ± 0.063	4.442ArgGlu: 4.442 ± 0.071	2.648ArgPhe: 2.648 ± 0.052	5.22ArgGly: 5.22 ± 0.083	1.976ArgHis: 1.976 ± 0.041	3.164ArgIle: 3.164 ± 0.058	1.771ArgLys: 1.771 ± 0.044	8.559ArgLeu: 8.559 ± 0.098	1.922ArgMet: 1.922 ± 0.045	1.512ArgAsn: 1.512 ± 0.039	3.528ArgPro: 3.528 ± 0.058	3.535ArgGln: 3.535 ± 0.065	5.587ArgArg: 5.587 ± 0.089	3.395ArgSer: 3.395 ± 0.056	3.373ArgThr: 3.373 ± 0.061	5.344ArgVal: 5.344 ± 0.078	1.34ArgTrp: 1.34 ± 0.038	1.688ArgTyr: 1.688 ± 0.041	0.0ArgXaa: 0.0 ± 0.0
Ser	6.438SerAla: 6.438 ± 0.098	0.426SerCys: 0.426 ± 0.024	2.294SerAsp: 2.294 ± 0.052	2.22SerGlu: 2.22 ± 0.048	1.793SerPhe: 1.793 ± 0.044	4.947SerGly: 4.947 ± 0.082	1.135SerHis: 1.135 ± 0.033	1.996SerIle: 1.996 ± 0.046	1.122SerLys: 1.122 ± 0.039	5.148SerLeu: 5.148 ± 0.071	1.202SerMet: 1.202 ± 0.037	1.141SerAsn: 1.141 ± 0.035	2.769SerPro: 2.769 ± 0.055	1.951SerGln: 1.951 ± 0.048	3.327SerArg: 3.327 ± 0.049	2.819SerSer: 2.819 ± 0.07	2.487SerThr: 2.487 ± 0.053	3.638SerVal: 3.638 ± 0.059	0.701SerTrp: 0.701 ± 0.026	1.167SerTyr: 1.167 ± 0.039	0.0SerXaa: 0.0 ± 0.0
Thr	5.969ThrAla: 5.969 ± 0.087	0.393ThrCys: 0.393 ± 0.022	2.172ThrAsp: 2.172 ± 0.055	2.124ThrGlu: 2.124 ± 0.049	1.564ThrPhe: 1.564 ± 0.042	4.66ThrGly: 4.66 ± 0.082	1.15ThrHis: 1.15 ± 0.037	1.88ThrIle: 1.88 ± 0.051	1.011ThrLys: 1.011 ± 0.041	6.204ThrLeu: 6.204 ± 0.068	0.958ThrMet: 0.958 ± 0.035	1.03ThrAsn: 1.03 ± 0.036	3.494ThrPro: 3.494 ± 0.06	2.052ThrGln: 2.052 ± 0.052	3.28ThrArg: 3.28 ± 0.055	2.365ThrSer: 2.365 ± 0.057	2.549ThrThr: 2.549 ± 0.051	3.909ThrVal: 3.909 ± 0.065	0.612ThrTrp: 0.612 ± 0.028	0.961ThrTyr: 0.961 ± 0.034	0.0ThrXaa: 0.0 ± 0.0
Val	10.107ValAla: 10.107 ± 0.114	0.78ValCys: 0.78 ± 0.032	3.757ValAsp: 3.757 ± 0.073	3.787ValGlu: 3.787 ± 0.066	2.473ValPhe: 2.473 ± 0.052	5.645ValGly: 5.645 ± 0.075	1.807ValHis: 1.807 ± 0.043	3.019ValIle: 3.019 ± 0.062	1.923ValLys: 1.923 ± 0.054	8.915ValLeu: 8.915 ± 0.121	1.828ValMet: 1.828 ± 0.044	1.895ValAsn: 1.895 ± 0.048	4.147ValPro: 4.147 ± 0.069	4.004ValGln: 4.004 ± 0.068	5.745ValArg: 5.745 ± 0.08	3.475ValSer: 3.475 ± 0.066	3.782ValThr: 3.782 ± 0.069	6.192ValVal: 6.192 ± 0.092	1.026ValTrp: 1.026 ± 0.04	1.397ValTyr: 1.397 ± 0.039	0.0ValXaa: 0.0 ± 0.0
Trp	1.577TrpAla: 1.577 ± 0.042	0.179TrpCys: 0.179 ± 0.014	0.618TrpAsp: 0.618 ± 0.029	0.558TrpGlu: 0.558 ± 0.024	0.528TrpPhe: 0.528 ± 0.025	1.11TrpGly: 1.11 ± 0.035	0.396TrpHis: 0.396 ± 0.02	0.556TrpIle: 0.556 ± 0.027	0.35TrpLys: 0.35 ± 0.018	2.347TrpLeu: 2.347 ± 0.051	0.421TrpMet: 0.421 ± 0.021	0.354TrpAsn: 0.354 ± 0.02	0.792TrpPro: 0.792 ± 0.033	0.951TrpGln: 0.951 ± 0.033	1.397TrpArg: 1.397 ± 0.046	0.819TrpSer: 0.819 ± 0.028	0.689TrpThr: 0.689 ± 0.022	1.021TrpVal: 1.021 ± 0.033	0.328TrpTrp: 0.328 ± 0.019	0.28TrpTyr: 0.28 ± 0.019	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.615TyrAla: 2.615 ± 0.055	0.226TyrCys: 0.226 ± 0.015	1.097TyrAsp: 1.097 ± 0.032	1.141TyrGlu: 1.141 ± 0.037	0.833TyrPhe: 0.833 ± 0.035	1.983TyrGly: 1.983 ± 0.052	0.456TyrHis: 0.456 ± 0.021	0.673TyrIle: 0.673 ± 0.025	0.574TyrLys: 0.574 ± 0.029	2.324TyrLeu: 2.324 ± 0.045	0.407TyrMet: 0.407 ± 0.017	0.531TyrAsn: 0.531 ± 0.024	1.009TyrPro: 1.009 ± 0.034	0.882TyrGln: 0.882 ± 0.032	1.53TyrArg: 1.53 ± 0.044	1.031TyrSer: 1.031 ± 0.033	1.119TyrThr: 1.119 ± 0.038	1.496TyrVal: 1.496 ± 0.04	0.34TyrTrp: 0.34 ± 0.019	0.542TyrTyr: 0.542 ± 0.026	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 2968 proteins (1000936 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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