Amino acid dipepetide frequency for Changjiang crawfish virus 6

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
4.515AlaAla: 4.515 ± 0.591
2.257AlaCys: 2.257 ± 0.169
1.935AlaAsp: 1.935 ± 0.941
1.935AlaGlu: 1.935 ± 0.941
3.547AlaPhe: 3.547 ± 0.796
5.482AlaGly: 5.482 ± 0.808
0.645AlaHis: 0.645 ± 0.615
3.87AlaIle: 3.87 ± 0.953
4.192AlaLys: 4.192 ± 2.038
5.482AlaLeu: 5.482 ± 2.665
2.257AlaMet: 2.257 ± 1.097
3.87AlaAsn: 3.87 ± 0.024
0.967AlaPro: 0.967 ± 1.387
2.257AlaGln: 2.257 ± 0.76
3.87AlaArg: 3.87 ± 0.024
4.515AlaSer: 4.515 ± 0.338
2.257AlaThr: 2.257 ± 0.76
4.515AlaVal: 4.515 ± 1.266
0.645AlaTrp: 0.645 ± 0.314
2.257AlaTyr: 2.257 ± 0.169
0.0AlaXaa: 0.0 ± 0.0
Cys
0.967CysAla: 0.967 ± 0.47
0.0CysCys: 0.0 ± 0.0
1.612CysAsp: 1.612 ± 2.002
2.257CysGlu: 2.257 ± 0.169
1.29CysPhe: 1.29 ± 0.302
0.967CysGly: 0.967 ± 0.47
0.0CysHis: 0.0 ± 0.0
0.967CysIle: 0.967 ± 0.458
1.29CysLys: 1.29 ± 0.627
1.935CysLeu: 1.935 ± 0.941
0.645CysMet: 0.645 ± 0.314
0.967CysAsn: 0.967 ± 0.47
0.967CysPro: 0.967 ± 0.458
0.645CysGln: 0.645 ± 0.314
0.322CysArg: 0.322 ± 0.157
2.257CysSer: 2.257 ± 0.169
0.967CysThr: 0.967 ± 0.47
1.29CysVal: 1.29 ± 0.627
0.322CysTrp: 0.322 ± 0.157
1.29CysTyr: 1.29 ± 0.627
0.0CysXaa: 0.0 ± 0.0
Asp
1.612AspAla: 1.612 ± 1.074
0.645AspCys: 0.645 ± 0.314
3.547AspAsp: 3.547 ± 0.133
3.87AspGlu: 3.87 ± 0.905
4.515AspPhe: 4.515 ± 0.338
2.257AspGly: 2.257 ± 1.097
0.322AspHis: 0.322 ± 0.157
3.225AspIle: 3.225 ± 1.218
3.87AspLys: 3.87 ± 0.024
3.547AspLeu: 3.547 ± 1.062
0.967AspMet: 0.967 ± 0.458
3.87AspAsn: 3.87 ± 0.905
3.547AspPro: 3.547 ± 1.725
0.967AspGln: 0.967 ± 0.458
0.967AspArg: 0.967 ± 0.47
6.127AspSer: 6.127 ± 2.05
1.612AspThr: 1.612 ± 0.145
2.58AspVal: 2.58 ± 1.254
1.29AspTrp: 1.29 ± 0.302
1.29AspTyr: 1.29 ± 1.23
0.0AspXaa: 0.0 ± 0.0
Glu
4.515GluAla: 4.515 ± 0.338
0.322GluCys: 0.322 ± 0.772
3.547GluAsp: 3.547 ± 0.796
5.805GluGlu: 5.805 ± 1.893
4.837GluPhe: 4.837 ± 2.292
2.58GluGly: 2.58 ± 0.326
0.967GluHis: 0.967 ± 0.47
3.87GluIle: 3.87 ± 0.953
6.127GluLys: 6.127 ± 0.193
5.482GluLeu: 5.482 ± 1.737
0.967GluMet: 0.967 ± 0.458
3.225GluAsn: 3.225 ± 0.639
2.257GluPro: 2.257 ± 0.169
3.547GluGln: 3.547 ± 0.133
3.87GluArg: 3.87 ± 0.953
2.58GluSer: 2.58 ± 0.603
2.902GluThr: 2.902 ± 0.446
4.515GluVal: 4.515 ± 1.266
0.967GluTrp: 0.967 ± 0.458
4.837GluTyr: 4.837 ± 2.352
0.0GluXaa: 0.0 ± 0.0
Phe
1.612PheAla: 1.612 ± 0.145
2.257PheCys: 2.257 ± 0.76
2.257PheAsp: 2.257 ± 0.76
2.902PheGlu: 2.902 ± 0.482
0.967PhePhe: 0.967 ± 0.47
3.87PheGly: 3.87 ± 0.953
1.612PheHis: 1.612 ± 0.784
3.225PheIle: 3.225 ± 1.568
3.225PheLys: 3.225 ± 0.639
3.87PheLeu: 3.87 ± 1.881
1.29PheMet: 1.29 ± 0.559
4.192PheAsn: 4.192 ± 2.605
0.967PhePro: 0.967 ± 0.458
1.612PheGln: 1.612 ± 2.002
1.29PheArg: 1.29 ± 1.23
5.805PheSer: 5.805 ± 0.036
3.87PheThr: 3.87 ± 1.833
2.902PheVal: 2.902 ± 3.233
0.322PheTrp: 0.322 ± 0.157
1.935PheTyr: 1.935 ± 0.012
0.0PheXaa: 0.0 ± 0.0
Gly
1.935GlyAla: 1.935 ± 0.941
0.645GlyCys: 0.645 ± 0.314
1.612GlyAsp: 1.612 ± 0.145
3.547GlyGlu: 3.547 ± 0.796
3.225GlyPhe: 3.225 ± 1.218
2.257GlyGly: 2.257 ± 1.689
0.322GlyHis: 0.322 ± 0.772
3.87GlyIle: 3.87 ± 0.953
4.837GlyLys: 4.837 ± 1.423
3.87GlyLeu: 3.87 ± 2.762
1.29GlyMet: 1.29 ± 0.302
2.58GlyAsn: 2.58 ± 0.326
1.612GlyPro: 1.612 ± 0.145
2.902GlyGln: 2.902 ± 1.375
2.58GlyArg: 2.58 ± 0.603
3.547GlySer: 3.547 ± 0.796
2.902GlyThr: 2.902 ± 0.482
4.515GlyVal: 4.515 ± 0.338
0.322GlyTrp: 0.322 ± 0.157
2.257GlyTyr: 2.257 ± 1.689
0.0GlyXaa: 0.0 ± 0.0
His
1.935HisAla: 1.935 ± 0.941
0.322HisCys: 0.322 ± 0.157
1.29HisAsp: 1.29 ± 0.627
1.612HisGlu: 1.612 ± 0.784
0.645HisPhe: 0.645 ± 0.615
0.645HisGly: 0.645 ± 0.314
0.0HisHis: 0.0 ± 0.0
0.967HisIle: 0.967 ± 0.47
0.967HisLys: 0.967 ± 0.47
2.902HisLeu: 2.902 ± 0.446
0.322HisMet: 0.322 ± 0.157
0.967HisAsn: 0.967 ± 0.47
1.29HisPro: 1.29 ± 0.302
1.29HisGln: 1.29 ± 1.23
1.612HisArg: 1.612 ± 0.784
0.0HisSer: 0.0 ± 0.0
0.645HisThr: 0.645 ± 0.314
1.935HisVal: 1.935 ± 0.941
0.0HisTrp: 0.0 ± 0.0
0.0HisTyr: 0.0 ± 0.0
0.0HisXaa: 0.0 ± 0.0
Ile
3.87IleAla: 3.87 ± 0.953
1.612IleCys: 1.612 ± 0.784
2.902IleAsp: 2.902 ± 1.375
3.547IleGlu: 3.547 ± 1.725
2.58IlePhe: 2.58 ± 0.603
4.192IleGly: 4.192 ± 1.109
1.29IleHis: 1.29 ± 0.302
4.515IleIle: 4.515 ± 0.338
4.837IleLys: 4.837 ± 1.423
5.16IleLeu: 5.16 ± 0.651
1.29IleMet: 1.29 ± 0.696
2.58IleAsn: 2.58 ± 0.603
3.547IlePro: 3.547 ± 0.796
2.257IleGln: 2.257 ± 1.097
2.58IleArg: 2.58 ± 0.603
3.547IleSer: 3.547 ± 1.062
5.482IleThr: 5.482 ± 1.737
5.482IleVal: 5.482 ± 0.808
0.645IleTrp: 0.645 ± 0.615
2.58IleTyr: 2.58 ± 1.254
0.0IleXaa: 0.0 ± 0.0
Lys
5.16LysAla: 5.16 ± 0.278
0.645LysCys: 0.645 ± 0.314
4.837LysAsp: 4.837 ± 0.434
5.805LysGlu: 5.805 ± 0.965
1.612LysPhe: 1.612 ± 0.784
2.58LysGly: 2.58 ± 0.326
1.935LysHis: 1.935 ± 0.941
4.192LysIle: 4.192 ± 2.038
4.192LysLys: 4.192 ± 2.038
5.482LysLeu: 5.482 ± 0.808
1.29LysMet: 1.29 ± 0.627
4.192LysAsn: 4.192 ± 1.109
3.547LysPro: 3.547 ± 0.796
2.257LysGln: 2.257 ± 1.097
3.225LysArg: 3.225 ± 0.639
3.225LysSer: 3.225 ± 1.568
4.515LysThr: 4.515 ± 1.266
5.482LysVal: 5.482 ± 0.808
0.322LysTrp: 0.322 ± 0.157
4.837LysTyr: 4.837 ± 0.434
0.0LysXaa: 0.0 ± 0.0
Leu
6.772LeuAla: 6.772 ± 1.435
2.58LeuCys: 2.58 ± 1.254
2.58LeuAsp: 2.58 ± 0.326
6.45LeuGlu: 6.45 ± 2.207
3.225LeuPhe: 3.225 ± 0.29
2.902LeuGly: 2.902 ± 1.375
1.612LeuHis: 1.612 ± 0.784
4.837LeuIle: 4.837 ± 0.494
4.515LeuLys: 4.515 ± 0.338
6.45LeuLeu: 6.45 ± 1.278
1.612LeuMet: 1.612 ± 0.784
7.094LeuAsn: 7.094 ± 0.266
1.935LeuPro: 1.935 ± 1.845
2.257LeuGln: 2.257 ± 1.689
5.482LeuArg: 5.482 ± 0.121
4.515LeuSer: 4.515 ± 0.591
6.45LeuThr: 6.45 ± 0.579
3.87LeuVal: 3.87 ± 0.024
0.322LeuTrp: 0.322 ± 0.157
3.225LeuTyr: 3.225 ± 1.218
0.0LeuXaa: 0.0 ± 0.0
Met
0.967MetAla: 0.967 ± 0.458
0.322MetCys: 0.322 ± 0.157
0.967MetAsp: 0.967 ± 0.458
1.29MetGlu: 1.29 ± 0.627
1.612MetPhe: 1.612 ± 0.145
0.645MetGly: 0.645 ± 0.615
0.322MetHis: 0.322 ± 0.157
2.58MetIle: 2.58 ± 0.603
2.257MetLys: 2.257 ± 0.169
1.935MetLeu: 1.935 ± 0.012
0.0MetMet: 0.0 ± 0.0
1.29MetAsn: 1.29 ± 0.627
1.29MetPro: 1.29 ± 0.302
1.612MetGln: 1.612 ± 1.074
0.967MetArg: 0.967 ± 0.47
1.612MetSer: 1.612 ± 0.145
1.29MetThr: 1.29 ± 0.627
1.29MetVal: 1.29 ± 0.627
0.0MetTrp: 0.0 ± 0.0
0.322MetTyr: 0.322 ± 0.157
0.0MetXaa: 0.0 ± 0.0
Asn
5.16AsnAla: 5.16 ± 0.278
1.29AsnCys: 1.29 ± 0.627
2.58AsnAsp: 2.58 ± 0.603
5.482AsnGlu: 5.482 ± 0.121
2.257AsnPhe: 2.257 ± 1.097
4.192AsnGly: 4.192 ± 0.748
0.967AsnHis: 0.967 ± 0.47
4.192AsnIle: 4.192 ± 1.109
4.192AsnLys: 4.192 ± 0.181
5.482AsnLeu: 5.482 ± 1.05
1.29AsnMet: 1.29 ± 1.23
2.902AsnAsn: 2.902 ± 0.482
2.58AsnPro: 2.58 ± 0.326
2.257AsnGln: 2.257 ± 2.617
1.612AsnArg: 1.612 ± 0.145
4.192AsnSer: 4.192 ± 1.677
2.257AsnThr: 2.257 ± 1.689
3.225AsnVal: 3.225 ± 0.639
0.322AsnTrp: 0.322 ± 0.157
3.87AsnTyr: 3.87 ± 1.833
0.0AsnXaa: 0.0 ± 0.0
Pro
2.58ProAla: 2.58 ± 1.254
0.967ProCys: 0.967 ± 0.458
2.58ProAsp: 2.58 ± 0.326
2.58ProGlu: 2.58 ± 0.326
2.257ProPhe: 2.257 ± 1.097
2.58ProGly: 2.58 ± 0.326
1.29ProHis: 1.29 ± 0.627
3.225ProIle: 3.225 ± 1.218
1.29ProLys: 1.29 ± 1.23
2.902ProLeu: 2.902 ± 0.446
0.967ProMet: 0.967 ± 0.47
3.225ProAsn: 3.225 ± 0.639
1.29ProPro: 1.29 ± 1.23
2.58ProGln: 2.58 ± 1.532
0.322ProArg: 0.322 ± 0.772
1.935ProSer: 1.935 ± 0.941
2.58ProThr: 2.58 ± 0.603
2.257ProVal: 2.257 ± 0.76
0.322ProTrp: 0.322 ± 0.157
2.257ProTyr: 2.257 ± 1.097
0.0ProXaa: 0.0 ± 0.0
Gln
2.902GlnAla: 2.902 ± 1.411
0.645GlnCys: 0.645 ± 0.314
1.935GlnAsp: 1.935 ± 0.941
1.612GlnGlu: 1.612 ± 1.074
2.58GlnPhe: 2.58 ± 0.603
1.935GlnGly: 1.935 ± 1.845
0.0GlnHis: 0.0 ± 0.0
2.58GlnIle: 2.58 ± 0.326
1.612GlnLys: 1.612 ± 0.145
2.58GlnLeu: 2.58 ± 1.532
1.29GlnMet: 1.29 ± 2.159
2.257GlnAsn: 2.257 ± 2.617
1.29GlnPro: 1.29 ± 0.627
4.515GlnGln: 4.515 ± 8.021
3.225GlnArg: 3.225 ± 1.218
2.902GlnSer: 2.902 ± 3.233
1.612GlnThr: 1.612 ± 1.074
3.87GlnVal: 3.87 ± 1.833
0.0GlnTrp: 0.0 ± 0.0
2.257GlnTyr: 2.257 ± 1.689
0.0GlnXaa: 0.0 ± 0.0
Arg
2.257ArgAla: 2.257 ± 0.169
0.967ArgCys: 0.967 ± 0.458
2.257ArgAsp: 2.257 ± 1.097
1.935ArgGlu: 1.935 ± 0.012
2.257ArgPhe: 2.257 ± 1.689
1.612ArgGly: 1.612 ± 1.074
1.612ArgHis: 1.612 ± 0.784
4.192ArgIle: 4.192 ± 0.748
3.547ArgLys: 3.547 ± 1.725
3.225ArgLeu: 3.225 ± 0.29
0.645ArgMet: 0.645 ± 0.314
2.257ArgAsn: 2.257 ± 2.617
1.935ArgPro: 1.935 ± 0.012
1.935ArgGln: 1.935 ± 1.845
1.935ArgArg: 1.935 ± 0.012
4.515ArgSer: 4.515 ± 0.338
3.225ArgThr: 3.225 ± 1.218
2.257ArgVal: 2.257 ± 0.169
0.0ArgTrp: 0.0 ± 0.0
2.257ArgTyr: 2.257 ± 1.097
0.0ArgXaa: 0.0 ± 0.0
Ser
4.515SerAla: 4.515 ± 0.338
2.257SerCys: 2.257 ± 0.169
3.225SerAsp: 3.225 ± 0.639
4.515SerGlu: 4.515 ± 2.195
3.225SerPhe: 3.225 ± 2.147
4.192SerGly: 4.192 ± 2.605
1.612SerHis: 1.612 ± 0.784
4.837SerIle: 4.837 ± 0.494
3.547SerLys: 3.547 ± 1.725
6.127SerLeu: 6.127 ± 2.593
2.58SerMet: 2.58 ± 0.326
5.482SerAsn: 5.482 ± 1.05
3.87SerPro: 3.87 ± 0.905
1.935SerGln: 1.935 ± 0.917
2.58SerArg: 2.58 ± 0.603
6.772SerSer: 6.772 ± 1.435
6.127SerThr: 6.127 ± 1.121
5.482SerVal: 5.482 ± 1.05
0.967SerTrp: 0.967 ± 0.458
1.612SerTyr: 1.612 ± 0.784
0.0SerXaa: 0.0 ± 0.0
Thr
2.257ThrAla: 2.257 ± 1.097
0.322ThrCys: 0.322 ± 0.157
2.902ThrAsp: 2.902 ± 2.304
4.515ThrGlu: 4.515 ± 0.591
3.547ThrPhe: 3.547 ± 0.133
2.58ThrGly: 2.58 ± 0.603
1.612ThrHis: 1.612 ± 0.145
3.87ThrIle: 3.87 ± 1.881
6.45ThrLys: 6.45 ± 1.278
3.547ThrLeu: 3.547 ± 0.796
0.322ThrMet: 0.322 ± 0.157
3.547ThrAsn: 3.547 ± 1.062
2.902ThrPro: 2.902 ± 0.482
2.257ThrGln: 2.257 ± 0.169
2.58ThrArg: 2.58 ± 0.603
6.127ThrSer: 6.127 ± 1.665
6.772ThrThr: 6.772 ± 1.435
3.547ThrVal: 3.547 ± 1.062
0.322ThrTrp: 0.322 ± 0.157
1.935ThrTyr: 1.935 ± 0.941
0.0ThrXaa: 0.0 ± 0.0
Val
3.87ValAla: 3.87 ± 0.953
0.645ValCys: 0.645 ± 0.314
3.87ValAsp: 3.87 ± 1.881
4.515ValGlu: 4.515 ± 2.449
2.58ValPhe: 2.58 ± 0.603
3.547ValGly: 3.547 ± 1.725
1.935ValHis: 1.935 ± 0.012
2.58ValIle: 2.58 ± 1.532
4.192ValLys: 4.192 ± 1.109
4.837ValLeu: 4.837 ± 2.352
1.935ValMet: 1.935 ± 0.941
2.902ValAsn: 2.902 ± 0.446
1.612ValPro: 1.612 ± 0.784
2.257ValGln: 2.257 ± 0.76
3.87ValArg: 3.87 ± 1.833
7.094ValSer: 7.094 ± 1.194
3.547ValThr: 3.547 ± 0.796
5.16ValVal: 5.16 ± 0.651
0.0ValTrp: 0.0 ± 0.0
5.16ValTyr: 5.16 ± 0.278
0.0ValXaa: 0.0 ± 0.0
Trp
0.322TrpAla: 0.322 ± 0.772
0.322TrpCys: 0.322 ± 0.157
0.322TrpAsp: 0.322 ± 0.157
0.645TrpGlu: 0.645 ± 1.544
0.967TrpPhe: 0.967 ± 0.47
0.0TrpGly: 0.0 ± 0.0
0.322TrpHis: 0.322 ± 0.157
0.0TrpIle: 0.0 ± 0.0
0.0TrpLys: 0.0 ± 0.0
0.322TrpLeu: 0.322 ± 0.157
0.645TrpMet: 0.645 ± 0.314
0.645TrpAsn: 0.645 ± 0.314
0.0TrpPro: 0.0 ± 0.0
0.322TrpGln: 0.322 ± 0.772
0.322TrpArg: 0.322 ± 0.157
0.967TrpSer: 0.967 ± 0.47
0.645TrpThr: 0.645 ± 0.314
0.645TrpVal: 0.645 ± 0.314
0.0TrpTrp: 0.0 ± 0.0
0.0TrpTyr: 0.0 ± 0.0
0.0TrpXaa: 0.0 ± 0.0
Tyr
3.547TyrAla: 3.547 ± 1.725
1.935TyrCys: 1.935 ± 0.012
3.87TyrAsp: 3.87 ± 0.024
2.902TyrGlu: 2.902 ± 0.482
2.257TyrPhe: 2.257 ± 0.169
1.612TyrGly: 1.612 ± 1.074
0.967TyrHis: 0.967 ± 0.458
3.225TyrIle: 3.225 ± 0.639
4.192TyrLys: 4.192 ± 1.109
3.547TyrLeu: 3.547 ± 1.99
0.645TyrMet: 0.645 ± 0.615
2.257TyrAsn: 2.257 ± 0.169
2.58TyrPro: 2.58 ± 0.326
1.935TyrGln: 1.935 ± 0.917
1.612TyrArg: 1.612 ± 0.145
3.225TyrSer: 3.225 ± 0.29
2.257TyrThr: 2.257 ± 0.169
1.29TyrVal: 1.29 ± 0.627
0.322TyrTrp: 0.322 ± 0.157
2.58TyrTyr: 2.58 ± 0.326
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 2 proteins (3102 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski