Amino acid dipepetide frequency for Streptococcus satellite phage Javan744

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
0.0AlaAla: 0.0 ± 0.0
0.347AlaCys: 0.347 ± 0.342
1.736AlaAsp: 1.736 ± 0.942
3.472AlaGlu: 3.472 ± 1.125
2.083AlaPhe: 2.083 ± 0.8
3.125AlaGly: 3.125 ± 0.905
0.694AlaHis: 0.694 ± 0.45
3.819AlaIle: 3.819 ± 1.493
7.639AlaLys: 7.639 ± 1.882
4.514AlaLeu: 4.514 ± 1.221
1.736AlaMet: 1.736 ± 1.006
2.778AlaAsn: 2.778 ± 0.952
0.694AlaPro: 0.694 ± 0.542
2.778AlaGln: 2.778 ± 0.977
3.472AlaArg: 3.472 ± 1.072
2.083AlaSer: 2.083 ± 1.025
4.167AlaThr: 4.167 ± 1.312
2.778AlaVal: 2.778 ± 1.035
0.347AlaTrp: 0.347 ± 0.334
2.778AlaTyr: 2.778 ± 1.021
0.0AlaXaa: 0.0 ± 0.0
Cys
0.694CysAla: 0.694 ± 0.498
0.0CysCys: 0.0 ± 0.0
0.347CysAsp: 0.347 ± 0.352
0.347CysGlu: 0.347 ± 0.307
0.347CysPhe: 0.347 ± 0.32
1.042CysGly: 1.042 ± 0.568
0.347CysHis: 0.347 ± 0.307
0.694CysIle: 0.694 ± 0.454
0.347CysLys: 0.347 ± 0.346
0.694CysLeu: 0.694 ± 0.43
0.347CysMet: 0.347 ± 0.338
0.347CysAsn: 0.347 ± 0.344
1.042CysPro: 1.042 ± 0.456
0.0CysGln: 0.0 ± 0.0
0.0CysArg: 0.0 ± 0.0
0.347CysSer: 0.347 ± 0.342
0.0CysThr: 0.0 ± 0.0
0.694CysVal: 0.694 ± 0.476
0.0CysTrp: 0.0 ± 0.0
0.347CysTyr: 0.347 ± 0.334
0.0CysXaa: 0.0 ± 0.0
Asp
1.389AspAla: 1.389 ± 0.483
0.694AspCys: 0.694 ± 0.396
5.556AspAsp: 5.556 ± 1.475
2.778AspGlu: 2.778 ± 0.851
3.472AspPhe: 3.472 ± 0.698
3.125AspGly: 3.125 ± 1.032
0.0AspHis: 0.0 ± 0.0
6.944AspIle: 6.944 ± 1.361
3.819AspLys: 3.819 ± 1.134
7.986AspLeu: 7.986 ± 2.038
1.042AspMet: 1.042 ± 0.547
6.597AspAsn: 6.597 ± 1.234
1.042AspPro: 1.042 ± 0.561
1.042AspGln: 1.042 ± 0.512
1.736AspArg: 1.736 ± 0.767
3.472AspSer: 3.472 ± 1.658
2.778AspThr: 2.778 ± 1.052
2.778AspVal: 2.778 ± 0.963
0.694AspTrp: 0.694 ± 0.447
3.125AspTyr: 3.125 ± 1.378
0.0AspXaa: 0.0 ± 0.0
Glu
2.431GluAla: 2.431 ± 1.001
1.736GluCys: 1.736 ± 0.652
4.514GluAsp: 4.514 ± 1.255
3.819GluGlu: 3.819 ± 0.914
3.819GluPhe: 3.819 ± 1.283
2.431GluGly: 2.431 ± 1.103
1.736GluHis: 1.736 ± 0.763
8.681GluIle: 8.681 ± 1.04
9.375GluLys: 9.375 ± 1.647
7.639GluLeu: 7.639 ± 1.768
2.431GluMet: 2.431 ± 0.813
7.292GluAsn: 7.292 ± 1.603
1.389GluPro: 1.389 ± 0.906
4.167GluGln: 4.167 ± 1.004
2.431GluArg: 2.431 ± 0.797
6.944GluSer: 6.944 ± 1.677
5.208GluThr: 5.208 ± 1.056
3.125GluVal: 3.125 ± 1.033
0.694GluTrp: 0.694 ± 0.454
3.472GluTyr: 3.472 ± 1.528
0.0GluXaa: 0.0 ± 0.0
Phe
1.389PheAla: 1.389 ± 0.763
0.694PheCys: 0.694 ± 0.689
2.778PheAsp: 2.778 ± 0.993
3.819PheGlu: 3.819 ± 1.637
1.736PhePhe: 1.736 ± 0.666
1.389PheGly: 1.389 ± 0.593
0.347PheHis: 0.347 ± 0.307
2.431PheIle: 2.431 ± 0.827
4.514PheLys: 4.514 ± 1.564
3.472PheLeu: 3.472 ± 1.217
0.694PheMet: 0.694 ± 0.422
2.083PheAsn: 2.083 ± 0.886
1.042PhePro: 1.042 ± 0.662
1.042PheGln: 1.042 ± 0.543
1.389PheArg: 1.389 ± 0.572
2.083PheSer: 2.083 ± 0.688
1.042PheThr: 1.042 ± 0.537
2.083PheVal: 2.083 ± 1.073
0.347PheTrp: 0.347 ± 0.289
1.736PheTyr: 1.736 ± 0.732
0.0PheXaa: 0.0 ± 0.0
Gly
2.778GlyAla: 2.778 ± 1.123
0.0GlyCys: 0.0 ± 0.0
0.694GlyAsp: 0.694 ± 0.457
4.514GlyGlu: 4.514 ± 0.932
0.347GlyPhe: 0.347 ± 0.338
1.736GlyGly: 1.736 ± 0.718
1.042GlyHis: 1.042 ± 0.493
3.125GlyIle: 3.125 ± 0.92
3.819GlyLys: 3.819 ± 1.284
4.167GlyLeu: 4.167 ± 0.898
2.431GlyMet: 2.431 ± 1.022
2.431GlyAsn: 2.431 ± 1.137
0.0GlyPro: 0.0 ± 0.0
2.431GlyGln: 2.431 ± 0.892
2.083GlyArg: 2.083 ± 0.74
2.431GlySer: 2.431 ± 0.866
2.431GlyThr: 2.431 ± 0.667
2.083GlyVal: 2.083 ± 0.865
0.347GlyTrp: 0.347 ± 0.344
4.167GlyTyr: 4.167 ± 1.262
0.0GlyXaa: 0.0 ± 0.0
His
2.083HisAla: 2.083 ± 0.958
0.0HisCys: 0.0 ± 0.0
1.042HisAsp: 1.042 ± 0.583
1.042HisGlu: 1.042 ± 0.56
0.347HisPhe: 0.347 ± 0.364
0.347HisGly: 0.347 ± 0.352
0.0HisHis: 0.0 ± 0.0
0.347HisIle: 0.347 ± 0.375
0.347HisLys: 0.347 ± 0.289
2.431HisLeu: 2.431 ± 0.944
0.0HisMet: 0.0 ± 0.0
0.694HisAsn: 0.694 ± 0.492
0.0HisPro: 0.0 ± 0.0
0.694HisGln: 0.694 ± 0.476
1.736HisArg: 1.736 ± 0.907
0.694HisSer: 0.694 ± 0.75
1.042HisThr: 1.042 ± 0.667
0.0HisVal: 0.0 ± 0.0
0.0HisTrp: 0.0 ± 0.0
0.347HisTyr: 0.347 ± 0.334
0.0HisXaa: 0.0 ± 0.0
Ile
3.125IleAla: 3.125 ± 1.123
0.0IleCys: 0.0 ± 0.0
5.903IleAsp: 5.903 ± 1.28
5.903IleGlu: 5.903 ± 1.714
3.472IlePhe: 3.472 ± 1.162
2.083IleGly: 2.083 ± 0.948
0.694IleHis: 0.694 ± 0.476
5.208IleIle: 5.208 ± 1.271
10.069IleLys: 10.069 ± 1.531
7.986IleLeu: 7.986 ± 1.765
1.042IleMet: 1.042 ± 0.577
4.167IleAsn: 4.167 ± 1.129
3.472IlePro: 3.472 ± 1.053
3.125IleGln: 3.125 ± 0.774
1.736IleArg: 1.736 ± 0.69
5.903IleSer: 5.903 ± 1.306
2.431IleThr: 2.431 ± 0.778
2.083IleVal: 2.083 ± 0.646
0.347IleTrp: 0.347 ± 0.352
3.125IleTyr: 3.125 ± 0.965
0.0IleXaa: 0.0 ± 0.0
Lys
6.25LysAla: 6.25 ± 1.459
1.042LysCys: 1.042 ± 0.522
5.556LysAsp: 5.556 ± 1.576
10.417LysGlu: 10.417 ± 2.155
3.125LysPhe: 3.125 ± 0.996
5.208LysGly: 5.208 ± 1.255
2.431LysHis: 2.431 ± 1.513
5.556LysIle: 5.556 ± 1.094
8.333LysLys: 8.333 ± 1.266
11.111LysLeu: 11.111 ± 2.558
2.083LysMet: 2.083 ± 0.92
7.986LysAsn: 7.986 ± 1.36
1.389LysPro: 1.389 ± 0.61
4.514LysGln: 4.514 ± 0.874
6.597LysArg: 6.597 ± 1.321
8.333LysSer: 8.333 ± 1.299
7.639LysThr: 7.639 ± 1.492
3.819LysVal: 3.819 ± 0.828
1.042LysTrp: 1.042 ± 0.546
4.514LysTyr: 4.514 ± 0.696
0.0LysXaa: 0.0 ± 0.0
Leu
6.597LeuAla: 6.597 ± 1.453
0.694LeuCys: 0.694 ± 0.526
7.639LeuAsp: 7.639 ± 1.414
11.458LeuGlu: 11.458 ± 1.376
2.431LeuPhe: 2.431 ± 0.877
4.861LeuGly: 4.861 ± 0.929
0.0LeuHis: 0.0 ± 0.0
6.944LeuIle: 6.944 ± 1.552
10.417LeuLys: 10.417 ± 1.569
8.681LeuLeu: 8.681 ± 1.453
2.083LeuMet: 2.083 ± 0.544
7.986LeuAsn: 7.986 ± 1.728
2.778LeuPro: 2.778 ± 0.962
4.861LeuGln: 4.861 ± 1.59
3.819LeuArg: 3.819 ± 0.795
5.903LeuSer: 5.903 ± 0.998
9.028LeuThr: 9.028 ± 1.863
4.167LeuVal: 4.167 ± 0.666
0.347LeuTrp: 0.347 ± 0.289
3.125LeuTyr: 3.125 ± 0.962
0.0LeuXaa: 0.0 ± 0.0
Met
2.431MetAla: 2.431 ± 1.077
0.0MetCys: 0.0 ± 0.0
2.083MetAsp: 2.083 ± 0.88
1.736MetGlu: 1.736 ± 0.772
0.347MetPhe: 0.347 ± 0.352
0.347MetGly: 0.347 ± 0.378
0.0MetHis: 0.0 ± 0.0
1.042MetIle: 1.042 ± 0.609
2.778MetLys: 2.778 ± 0.807
1.389MetLeu: 1.389 ± 0.479
0.0MetMet: 0.0 ± 0.0
1.736MetAsn: 1.736 ± 0.795
0.694MetPro: 0.694 ± 0.459
0.347MetGln: 0.347 ± 0.392
2.431MetArg: 2.431 ± 1.0
2.083MetSer: 2.083 ± 0.73
2.431MetThr: 2.431 ± 0.791
0.694MetVal: 0.694 ± 0.475
0.347MetTrp: 0.347 ± 0.345
0.0MetTyr: 0.0 ± 0.0
0.0MetXaa: 0.0 ± 0.0
Asn
3.819AsnAla: 3.819 ± 0.809
0.347AsnCys: 0.347 ± 0.307
1.736AsnAsp: 1.736 ± 0.86
3.125AsnGlu: 3.125 ± 1.117
2.083AsnPhe: 2.083 ± 0.631
2.778AsnGly: 2.778 ± 0.818
1.389AsnHis: 1.389 ± 0.831
4.167AsnIle: 4.167 ± 1.584
7.292AsnLys: 7.292 ± 1.944
5.903AsnLeu: 5.903 ± 1.624
2.083AsnMet: 2.083 ± 0.938
3.819AsnAsn: 3.819 ± 1.629
2.083AsnPro: 2.083 ± 0.738
4.861AsnGln: 4.861 ± 1.322
2.778AsnArg: 2.778 ± 1.023
6.25AsnSer: 6.25 ± 1.246
5.556AsnThr: 5.556 ± 1.395
1.389AsnVal: 1.389 ± 0.728
1.042AsnTrp: 1.042 ± 0.517
1.736AsnTyr: 1.736 ± 0.602
0.0AsnXaa: 0.0 ± 0.0
Pro
1.389ProAla: 1.389 ± 0.765
0.0ProCys: 0.0 ± 0.0
3.819ProAsp: 3.819 ± 1.022
1.736ProGlu: 1.736 ± 0.708
1.042ProPhe: 1.042 ± 0.456
0.347ProGly: 0.347 ± 0.289
0.347ProHis: 0.347 ± 0.342
2.083ProIle: 2.083 ± 0.741
4.167ProLys: 4.167 ± 1.209
0.347ProLeu: 0.347 ± 0.364
0.0ProMet: 0.0 ± 0.0
0.694ProAsn: 0.694 ± 0.428
1.389ProPro: 1.389 ± 0.764
0.694ProGln: 0.694 ± 0.373
2.083ProArg: 2.083 ± 1.013
1.042ProSer: 1.042 ± 0.63
1.042ProThr: 1.042 ± 0.657
1.736ProVal: 1.736 ± 0.581
0.0ProTrp: 0.0 ± 0.0
0.694ProTyr: 0.694 ± 0.474
0.0ProXaa: 0.0 ± 0.0
Gln
4.167GlnAla: 4.167 ± 1.054
0.0GlnCys: 0.0 ± 0.0
2.778GlnAsp: 2.778 ± 1.173
2.778GlnGlu: 2.778 ± 0.527
1.042GlnPhe: 1.042 ± 0.755
1.389GlnGly: 1.389 ± 0.621
0.0GlnHis: 0.0 ± 0.0
3.125GlnIle: 3.125 ± 0.692
5.208GlnLys: 5.208 ± 1.067
3.819GlnLeu: 3.819 ± 1.309
1.042GlnMet: 1.042 ± 0.779
2.778GlnAsn: 2.778 ± 0.808
1.042GlnPro: 1.042 ± 0.58
1.736GlnGln: 1.736 ± 0.766
1.042GlnArg: 1.042 ± 0.795
1.389GlnSer: 1.389 ± 0.732
1.389GlnThr: 1.389 ± 0.557
3.819GlnVal: 3.819 ± 1.071
0.694GlnTrp: 0.694 ± 0.418
1.042GlnTyr: 1.042 ± 0.692
0.0GlnXaa: 0.0 ± 0.0
Arg
1.736ArgAla: 1.736 ± 0.713
0.347ArgCys: 0.347 ± 0.393
2.083ArgAsp: 2.083 ± 0.715
5.556ArgGlu: 5.556 ± 1.591
1.389ArgPhe: 1.389 ± 1.12
0.694ArgGly: 0.694 ± 0.493
1.042ArgHis: 1.042 ± 0.58
1.736ArgIle: 1.736 ± 0.684
4.861ArgLys: 4.861 ± 1.373
6.944ArgLeu: 6.944 ± 1.723
0.694ArgMet: 0.694 ± 0.522
1.736ArgAsn: 1.736 ± 0.887
0.347ArgPro: 0.347 ± 0.289
2.431ArgGln: 2.431 ± 0.974
2.431ArgArg: 2.431 ± 1.072
1.389ArgSer: 1.389 ± 0.767
2.431ArgThr: 2.431 ± 0.637
2.431ArgVal: 2.431 ± 0.767
0.347ArgTrp: 0.347 ± 0.375
3.125ArgTyr: 3.125 ± 0.864
0.0ArgXaa: 0.0 ± 0.0
Ser
3.125SerAla: 3.125 ± 1.795
0.347SerCys: 0.347 ± 0.289
3.819SerAsp: 3.819 ± 0.924
7.639SerGlu: 7.639 ± 1.878
2.083SerPhe: 2.083 ± 0.822
5.208SerGly: 5.208 ± 1.053
0.694SerHis: 0.694 ± 0.428
3.819SerIle: 3.819 ± 0.904
7.292SerLys: 7.292 ± 1.581
6.25SerLeu: 6.25 ± 1.051
1.389SerMet: 1.389 ± 0.551
4.167SerAsn: 4.167 ± 1.352
1.389SerPro: 1.389 ± 0.537
1.389SerGln: 1.389 ± 0.641
2.431SerArg: 2.431 ± 0.987
3.819SerSer: 3.819 ± 1.312
3.472SerThr: 3.472 ± 1.053
3.125SerVal: 3.125 ± 0.728
0.347SerTrp: 0.347 ± 0.338
2.083SerTyr: 2.083 ± 0.917
0.0SerXaa: 0.0 ± 0.0
Thr
2.431ThrAla: 2.431 ± 1.006
0.694ThrCys: 0.694 ± 0.459
1.736ThrAsp: 1.736 ± 0.74
3.819ThrGlu: 3.819 ± 1.144
2.431ThrPhe: 2.431 ± 0.812
3.125ThrGly: 3.125 ± 0.923
1.389ThrHis: 1.389 ± 0.612
4.861ThrIle: 4.861 ± 1.243
6.25ThrLys: 6.25 ± 1.781
6.597ThrLeu: 6.597 ± 1.312
1.736ThrMet: 1.736 ± 0.599
3.125ThrAsn: 3.125 ± 1.099
1.736ThrPro: 1.736 ± 0.931
0.694ThrGln: 0.694 ± 0.442
1.389ThrArg: 1.389 ± 0.754
3.819ThrSer: 3.819 ± 1.005
5.556ThrThr: 5.556 ± 1.763
6.597ThrVal: 6.597 ± 1.683
1.389ThrTrp: 1.389 ± 0.776
4.167ThrTyr: 4.167 ± 1.433
0.0ThrXaa: 0.0 ± 0.0
Val
3.125ValAla: 3.125 ± 1.478
0.347ValCys: 0.347 ± 0.352
3.125ValAsp: 3.125 ± 0.97
4.861ValGlu: 4.861 ± 0.986
1.042ValPhe: 1.042 ± 0.502
2.778ValGly: 2.778 ± 1.298
0.347ValHis: 0.347 ± 0.334
4.167ValIle: 4.167 ± 1.314
4.514ValLys: 4.514 ± 1.437
5.208ValLeu: 5.208 ± 1.23
0.347ValMet: 0.347 ± 0.495
2.083ValAsn: 2.083 ± 0.756
1.389ValPro: 1.389 ± 0.578
2.083ValGln: 2.083 ± 0.886
2.083ValArg: 2.083 ± 0.723
3.125ValSer: 3.125 ± 1.044
2.431ValThr: 2.431 ± 0.744
2.431ValVal: 2.431 ± 1.074
0.347ValTrp: 0.347 ± 0.345
2.083ValTyr: 2.083 ± 0.971
0.0ValXaa: 0.0 ± 0.0
Trp
1.042TrpAla: 1.042 ± 0.456
0.0TrpCys: 0.0 ± 0.0
0.0TrpAsp: 0.0 ± 0.0
2.083TrpGlu: 2.083 ± 0.986
0.0TrpPhe: 0.0 ± 0.0
0.347TrpGly: 0.347 ± 0.375
0.347TrpHis: 0.347 ± 0.334
0.694TrpIle: 0.694 ± 0.479
1.042TrpLys: 1.042 ± 0.538
1.042TrpLeu: 1.042 ± 0.622
0.0TrpMet: 0.0 ± 0.0
0.0TrpAsn: 0.0 ± 0.0
0.347TrpPro: 0.347 ± 0.364
0.0TrpGln: 0.0 ± 0.0
0.0TrpArg: 0.0 ± 0.0
1.042TrpSer: 1.042 ± 0.528
0.0TrpThr: 0.0 ± 0.0
1.042TrpVal: 1.042 ± 0.522
0.0TrpTrp: 0.0 ± 0.0
0.0TrpTyr: 0.0 ± 0.0
0.0TrpXaa: 0.0 ± 0.0
Tyr
1.042TyrAla: 1.042 ± 0.663
0.694TyrCys: 0.694 ± 0.418
3.125TyrAsp: 3.125 ± 0.931
2.431TyrGlu: 2.431 ± 0.676
3.472TyrPhe: 3.472 ± 1.109
0.694TyrGly: 0.694 ± 0.437
0.347TyrHis: 0.347 ± 0.334
2.431TyrIle: 2.431 ± 0.914
4.861TyrLys: 4.861 ± 1.961
7.639TyrLeu: 7.639 ± 1.424
1.389TyrMet: 1.389 ± 0.758
1.736TyrAsn: 1.736 ± 0.649
1.389TyrPro: 1.389 ± 0.506
1.389TyrGln: 1.389 ± 0.601
2.083TyrArg: 2.083 ± 0.749
1.736TyrSer: 1.736 ± 0.936
3.472TyrThr: 3.472 ± 0.723
1.389TyrVal: 1.389 ± 0.837
0.347TyrTrp: 0.347 ± 0.344
0.694TyrTyr: 0.694 ± 0.455
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 20 proteins (2881 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski