Amino acid dipepetide frequency for California sea lion adenovirus 1

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
1.036AlaAla: 1.036 ± 1.164
3.109AlaCys: 3.109 ± 2.025
2.073AlaAsp: 2.073 ± 1.162
6.218AlaGlu: 6.218 ± 2.392
1.036AlaPhe: 1.036 ± 1.266
2.073AlaGly: 2.073 ± 2.327
1.036AlaHis: 1.036 ± 0.675
1.036AlaIle: 1.036 ± 0.675
3.109AlaLys: 3.109 ± 1.418
6.218AlaLeu: 6.218 ± 3.082
0.0AlaMet: 0.0 ± 0.0
4.145AlaAsn: 4.145 ± 3.697
2.073AlaPro: 2.073 ± 0.828
0.0AlaGln: 0.0 ± 0.0
3.109AlaArg: 3.109 ± 2.36
10.363AlaSer: 10.363 ± 4.328
4.145AlaThr: 4.145 ± 2.537
5.181AlaVal: 5.181 ± 0.552
1.036AlaTrp: 1.036 ± 1.266
1.036AlaTyr: 1.036 ± 0.675
0.0AlaXaa: 0.0 ± 0.0
Cys
1.036CysAla: 1.036 ± 0.675
3.109CysCys: 3.109 ± 1.196
1.036CysAsp: 1.036 ± 0.924
1.036CysGlu: 1.036 ± 0.675
0.0CysPhe: 0.0 ± 0.0
1.036CysGly: 1.036 ± 0.675
1.036CysHis: 1.036 ± 0.924
1.036CysIle: 1.036 ± 0.675
1.036CysLys: 1.036 ± 0.675
4.145CysLeu: 4.145 ± 1.657
2.073CysMet: 2.073 ± 0.787
1.036CysAsn: 1.036 ± 0.675
2.073CysPro: 2.073 ± 0.828
0.0CysGln: 0.0 ± 0.0
2.073CysArg: 2.073 ± 1.162
4.145CysSer: 4.145 ± 0.957
4.145CysThr: 4.145 ± 1.756
3.109CysVal: 3.109 ± 1.418
0.0CysTrp: 0.0 ± 0.0
3.109CysTyr: 3.109 ± 1.196
0.0CysXaa: 0.0 ± 0.0
Asp
4.145AspAla: 4.145 ± 2.679
1.036AspCys: 1.036 ± 0.924
9.326AspAsp: 9.326 ± 3.702
6.218AspGlu: 6.218 ± 2.514
4.145AspPhe: 4.145 ± 2.504
4.145AspGly: 4.145 ± 2.011
0.0AspHis: 0.0 ± 0.0
3.109AspIle: 3.109 ± 0.937
1.036AspLys: 1.036 ± 0.675
11.399AspLeu: 11.399 ± 3.983
2.073AspMet: 2.073 ± 1.327
3.109AspAsn: 3.109 ± 2.642
4.145AspPro: 4.145 ± 0.915
3.109AspGln: 3.109 ± 2.36
2.073AspArg: 2.073 ± 1.162
7.254AspSer: 7.254 ± 1.883
2.073AspThr: 2.073 ± 1.848
3.109AspVal: 3.109 ± 2.772
0.0AspTrp: 0.0 ± 0.0
4.145AspTyr: 4.145 ± 2.679
0.0AspXaa: 0.0 ± 0.0
Glu
4.145GluAla: 4.145 ± 1.454
0.0GluCys: 0.0 ± 0.0
7.254GluAsp: 7.254 ± 2.428
3.109GluGlu: 3.109 ± 1.655
4.145GluPhe: 4.145 ± 2.325
0.0GluGly: 0.0 ± 0.0
3.109GluHis: 3.109 ± 1.655
4.145GluIle: 4.145 ± 0.915
6.218GluLys: 6.218 ± 1.875
3.109GluLeu: 3.109 ± 1.901
1.036GluMet: 1.036 ± 0.872
9.326GluAsn: 9.326 ± 0.825
6.218GluPro: 6.218 ± 1.427
2.073GluGln: 2.073 ± 1.714
1.036GluArg: 1.036 ± 0.675
3.109GluSer: 3.109 ± 0.945
4.145GluThr: 4.145 ± 1.657
8.29GluVal: 8.29 ± 3.19
1.036GluTrp: 1.036 ± 0.675
1.036GluTyr: 1.036 ± 0.675
0.0GluXaa: 0.0 ± 0.0
Phe
2.073PheAla: 2.073 ± 0.828
3.109PheCys: 3.109 ± 2.335
5.181PheAsp: 5.181 ± 2.249
4.145PheGlu: 4.145 ± 1.454
4.145PhePhe: 4.145 ± 3.572
1.036PheGly: 1.036 ± 1.266
0.0PheHis: 0.0 ± 0.0
1.036PheIle: 1.036 ± 1.266
3.109PheLys: 3.109 ± 0.937
4.145PheLeu: 4.145 ± 1.033
1.036PheMet: 1.036 ± 1.266
2.073PheAsn: 2.073 ± 1.35
3.109PhePro: 3.109 ± 1.196
1.036PheGln: 1.036 ± 1.266
0.0PheArg: 0.0 ± 0.0
5.181PheSer: 5.181 ± 1.899
5.181PheThr: 5.181 ± 2.377
3.109PheVal: 3.109 ± 2.025
0.0PheTrp: 0.0 ± 0.0
1.036PheTyr: 1.036 ± 1.266
0.0PheXaa: 0.0 ± 0.0
Gly
2.073GlyAla: 2.073 ± 0.828
2.073GlyCys: 2.073 ± 1.35
3.109GlyAsp: 3.109 ± 2.067
3.109GlyGlu: 3.109 ± 0.937
2.073GlyPhe: 2.073 ± 1.162
2.073GlyGly: 2.073 ± 0.828
1.036GlyHis: 1.036 ± 1.266
3.109GlyIle: 3.109 ± 2.025
0.0GlyLys: 0.0 ± 0.0
2.073GlyLeu: 2.073 ± 1.005
0.0GlyMet: 0.0 ± 0.0
4.145GlyAsn: 4.145 ± 2.325
1.036GlyPro: 1.036 ± 0.675
1.036GlyGln: 1.036 ± 0.675
0.0GlyArg: 0.0 ± 0.0
5.181GlySer: 5.181 ± 3.329
2.073GlyThr: 2.073 ± 1.35
3.109GlyVal: 3.109 ± 1.196
0.0GlyTrp: 0.0 ± 0.0
0.0GlyTyr: 0.0 ± 0.0
0.0GlyXaa: 0.0 ± 0.0
His
2.073HisAla: 2.073 ± 1.162
0.0HisCys: 0.0 ± 0.0
4.145HisAsp: 4.145 ± 1.657
2.073HisGlu: 2.073 ± 0.828
2.073HisPhe: 2.073 ± 0.828
0.0HisGly: 0.0 ± 0.0
0.0HisHis: 0.0 ± 0.0
2.073HisIle: 2.073 ± 1.162
0.0HisLys: 0.0 ± 0.0
1.036HisLeu: 1.036 ± 0.924
0.0HisMet: 0.0 ± 0.0
2.073HisAsn: 2.073 ± 1.162
1.036HisPro: 1.036 ± 0.924
1.036HisGln: 1.036 ± 0.924
2.073HisArg: 2.073 ± 1.363
3.109HisSer: 3.109 ± 2.067
1.036HisThr: 1.036 ± 1.164
0.0HisVal: 0.0 ± 0.0
0.0HisTrp: 0.0 ± 0.0
1.036HisTyr: 1.036 ± 0.675
0.0HisXaa: 0.0 ± 0.0
Ile
2.073IleAla: 2.073 ± 0.828
1.036IleCys: 1.036 ± 0.675
1.036IleAsp: 1.036 ± 1.164
3.109IleGlu: 3.109 ± 1.196
3.109IlePhe: 3.109 ± 1.196
3.109IleGly: 3.109 ± 2.025
1.036IleHis: 1.036 ± 1.164
6.218IleIle: 6.218 ± 3.076
4.145IleLys: 4.145 ± 2.7
4.145IleLeu: 4.145 ± 2.444
0.0IleMet: 0.0 ± 0.0
0.0IleAsn: 0.0 ± 0.0
2.073IlePro: 2.073 ± 1.324
2.073IleGln: 2.073 ± 2.327
0.0IleArg: 0.0 ± 0.0
3.109IleSer: 3.109 ± 0.937
3.109IleThr: 3.109 ± 1.196
3.109IleVal: 3.109 ± 1.196
0.0IleTrp: 0.0 ± 0.0
0.0IleTyr: 0.0 ± 0.0
1.036IleXaa: 1.036 ± 0.675
Lys
2.073LysAla: 2.073 ± 1.162
2.073LysCys: 2.073 ± 1.35
2.073LysAsp: 2.073 ± 1.324
3.109LysGlu: 3.109 ± 1.901
1.036LysPhe: 1.036 ± 1.266
1.036LysGly: 1.036 ± 0.675
2.073LysHis: 2.073 ± 0.828
3.109LysIle: 3.109 ± 2.025
2.073LysLys: 2.073 ± 0.828
5.181LysLeu: 5.181 ± 1.365
1.036LysMet: 1.036 ± 0.675
1.036LysAsn: 1.036 ± 1.164
1.036LysPro: 1.036 ± 0.675
0.0LysGln: 0.0 ± 0.0
1.036LysArg: 1.036 ± 0.924
3.109LysSer: 3.109 ± 1.196
1.036LysThr: 1.036 ± 0.675
8.29LysVal: 8.29 ± 2.839
0.0LysTrp: 0.0 ± 0.0
0.0LysTyr: 0.0 ± 0.0
0.0LysXaa: 0.0 ± 0.0
Leu
8.29LeuAla: 8.29 ± 4.864
2.073LeuCys: 2.073 ± 1.848
12.435LeuAsp: 12.435 ± 6.45
10.363LeuGlu: 10.363 ± 1.051
6.218LeuPhe: 6.218 ± 1.929
1.036LeuGly: 1.036 ± 0.675
3.109LeuHis: 3.109 ± 1.62
6.218LeuIle: 6.218 ± 1.961
3.109LeuLys: 3.109 ± 0.937
6.218LeuLeu: 6.218 ± 2.121
0.0LeuMet: 0.0 ± 0.0
3.109LeuAsn: 3.109 ± 1.257
7.254LeuPro: 7.254 ± 3.123
3.109LeuGln: 3.109 ± 0.945
4.145LeuArg: 4.145 ± 1.323
6.218LeuSer: 6.218 ± 1.961
3.109LeuThr: 3.109 ± 1.374
2.073LeuVal: 2.073 ± 0.828
0.0LeuTrp: 0.0 ± 0.0
2.073LeuTyr: 2.073 ± 1.162
0.0LeuXaa: 0.0 ± 0.0
Met
1.036MetAla: 1.036 ± 0.675
0.0MetCys: 0.0 ± 0.0
2.073MetAsp: 2.073 ± 2.327
2.073MetGlu: 2.073 ± 2.532
1.036MetPhe: 1.036 ± 0.924
1.036MetGly: 1.036 ± 0.675
0.0MetHis: 0.0 ± 0.0
0.0MetIle: 0.0 ± 0.0
1.036MetLys: 1.036 ± 0.675
0.0MetLeu: 0.0 ± 0.0
3.109MetMet: 3.109 ± 2.335
0.0MetAsn: 0.0 ± 0.0
1.036MetPro: 1.036 ± 0.924
0.0MetGln: 0.0 ± 0.0
2.073MetArg: 2.073 ± 0.828
1.036MetSer: 1.036 ± 1.266
0.0MetThr: 0.0 ± 0.0
1.036MetVal: 1.036 ± 0.924
0.0MetTrp: 0.0 ± 0.0
0.0MetTyr: 0.0 ± 0.0
0.0MetXaa: 0.0 ± 0.0
Asn
2.073AsnAla: 2.073 ± 1.35
5.181AsnCys: 5.181 ± 1.943
1.036AsnAsp: 1.036 ± 0.924
3.109AsnGlu: 3.109 ± 0.945
2.073AsnPhe: 2.073 ± 1.162
2.073AsnGly: 2.073 ± 0.828
2.073AsnHis: 2.073 ± 2.327
3.109AsnIle: 3.109 ± 2.067
2.073AsnLys: 2.073 ± 1.162
2.073AsnLeu: 2.073 ± 1.162
3.109AsnMet: 3.109 ± 2.603
3.109AsnAsn: 3.109 ± 1.418
3.109AsnPro: 3.109 ± 1.196
5.181AsnGln: 5.181 ± 3.583
1.036AsnArg: 1.036 ± 1.164
5.181AsnSer: 5.181 ± 1.302
0.0AsnThr: 0.0 ± 0.0
0.0AsnVal: 0.0 ± 0.0
1.036AsnTrp: 1.036 ± 0.675
1.036AsnTyr: 1.036 ± 1.164
0.0AsnXaa: 0.0 ± 0.0
Pro
4.145ProAla: 4.145 ± 1.033
0.0ProCys: 0.0 ± 0.0
3.109ProAsp: 3.109 ± 1.62
7.254ProGlu: 7.254 ± 3.878
2.073ProPhe: 2.073 ± 1.324
2.073ProGly: 2.073 ± 0.828
1.036ProHis: 1.036 ± 0.924
2.073ProIle: 2.073 ± 1.363
3.109ProLys: 3.109 ± 1.196
5.181ProLeu: 5.181 ± 2.402
0.0ProMet: 0.0 ± 0.0
1.036ProAsn: 1.036 ± 0.675
4.145ProPro: 4.145 ± 2.827
1.036ProGln: 1.036 ± 0.675
1.036ProArg: 1.036 ± 0.675
6.218ProSer: 6.218 ± 1.427
2.073ProThr: 2.073 ± 2.327
4.145ProVal: 4.145 ± 2.504
0.0ProTrp: 0.0 ± 0.0
3.109ProTyr: 3.109 ± 1.196
1.036ProXaa: 1.036 ± 0.675
Gln
3.109GlnAla: 3.109 ± 1.196
1.036GlnCys: 1.036 ± 0.924
4.145GlnAsp: 4.145 ± 3.463
1.036GlnGlu: 1.036 ± 1.164
0.0GlnPhe: 0.0 ± 0.0
2.073GlnGly: 2.073 ± 1.714
1.036GlnHis: 1.036 ± 0.675
0.0GlnIle: 0.0 ± 0.0
2.073GlnLys: 2.073 ± 1.714
4.145GlnLeu: 4.145 ± 1.033
0.0GlnMet: 0.0 ± 0.0
1.036GlnAsn: 1.036 ± 1.164
1.036GlnPro: 1.036 ± 0.924
3.109GlnGln: 3.109 ± 3.491
0.0GlnArg: 0.0 ± 0.0
2.073GlnSer: 2.073 ± 2.327
1.036GlnThr: 1.036 ± 1.266
2.073GlnVal: 2.073 ± 1.714
0.0GlnTrp: 0.0 ± 0.0
1.036GlnTyr: 1.036 ± 0.675
1.036GlnXaa: 1.036 ± 1.164
Arg
3.109ArgAla: 3.109 ± 0.945
0.0ArgCys: 0.0 ± 0.0
0.0ArgAsp: 0.0 ± 0.0
1.036ArgGlu: 1.036 ± 0.675
2.073ArgPhe: 2.073 ± 1.162
1.036ArgGly: 1.036 ± 0.675
1.036ArgHis: 1.036 ± 0.675
0.0ArgIle: 0.0 ± 0.0
2.073ArgLys: 2.073 ± 0.828
4.145ArgLeu: 4.145 ± 2.266
0.0ArgMet: 0.0 ± 0.0
1.036ArgAsn: 1.036 ± 1.164
2.073ArgPro: 2.073 ± 1.324
3.109ArgGln: 3.109 ± 0.945
3.109ArgArg: 3.109 ± 1.257
1.036ArgSer: 1.036 ± 0.675
1.036ArgThr: 1.036 ± 1.266
1.036ArgVal: 1.036 ± 1.164
0.0ArgTrp: 0.0 ± 0.0
0.0ArgTyr: 0.0 ± 0.0
0.0ArgXaa: 0.0 ± 0.0
Ser
6.218SerAla: 6.218 ± 2.706
3.109SerCys: 3.109 ± 1.62
7.254SerAsp: 7.254 ± 1.784
6.218SerGlu: 6.218 ± 0.753
5.181SerPhe: 5.181 ± 3.758
4.145SerGly: 4.145 ± 1.323
2.073SerHis: 2.073 ± 1.324
3.109SerIle: 3.109 ± 0.945
3.109SerLys: 3.109 ± 1.196
15.544SerLeu: 15.544 ± 3.183
0.0SerMet: 0.0 ± 0.0
5.181SerAsn: 5.181 ± 3.036
5.181SerPro: 5.181 ± 4.621
2.073SerGln: 2.073 ± 1.162
2.073SerArg: 2.073 ± 1.005
9.326SerSer: 9.326 ± 4.161
4.145SerThr: 4.145 ± 1.033
8.29SerVal: 8.29 ± 2.289
0.0SerTrp: 0.0 ± 0.0
1.036SerTyr: 1.036 ± 0.675
0.0SerXaa: 0.0 ± 0.0
Thr
4.145ThrAla: 4.145 ± 2.266
4.145ThrCys: 4.145 ± 2.7
3.109ThrAsp: 3.109 ± 1.418
0.0ThrGlu: 0.0 ± 0.0
3.109ThrPhe: 3.109 ± 2.025
3.109ThrGly: 3.109 ± 2.335
1.036ThrHis: 1.036 ± 0.675
0.0ThrIle: 0.0 ± 0.0
0.0ThrLys: 0.0 ± 0.0
5.181ThrLeu: 5.181 ± 3.691
0.0ThrMet: 0.0 ± 0.0
2.073ThrAsn: 2.073 ± 1.35
2.073ThrPro: 2.073 ± 0.828
0.0ThrGln: 0.0 ± 0.0
0.0ThrArg: 0.0 ± 0.0
5.181ThrSer: 5.181 ± 2.404
0.0ThrThr: 0.0 ± 0.0
3.109ThrVal: 3.109 ± 1.655
2.073ThrTrp: 2.073 ± 1.005
3.109ThrTyr: 3.109 ± 1.257
0.0ThrXaa: 0.0 ± 0.0
Val
3.109ValAla: 3.109 ± 0.945
3.109ValCys: 3.109 ± 0.937
4.145ValAsp: 4.145 ± 1.575
8.29ValGlu: 8.29 ± 1.867
5.181ValPhe: 5.181 ± 1.365
4.145ValGly: 4.145 ± 0.957
3.109ValHis: 3.109 ± 2.025
2.073ValIle: 2.073 ± 1.35
0.0ValLys: 0.0 ± 0.0
5.181ValLeu: 5.181 ± 1.943
1.036ValMet: 1.036 ± 0.675
3.109ValAsn: 3.109 ± 1.901
3.109ValPro: 3.109 ± 1.257
2.073ValGln: 2.073 ± 2.327
1.036ValArg: 1.036 ± 0.675
8.29ValSer: 8.29 ± 2.637
2.073ValThr: 2.073 ± 1.35
8.29ValVal: 8.29 ± 2.646
0.0ValTrp: 0.0 ± 0.0
2.073ValTyr: 2.073 ± 1.162
0.0ValXaa: 0.0 ± 0.0
Trp
1.036TrpAla: 1.036 ± 1.164
0.0TrpCys: 0.0 ± 0.0
0.0TrpAsp: 0.0 ± 0.0
1.036TrpGlu: 1.036 ± 0.675
0.0TrpPhe: 0.0 ± 0.0
0.0TrpGly: 0.0 ± 0.0
0.0TrpHis: 0.0 ± 0.0
1.036TrpIle: 1.036 ± 0.675
0.0TrpLys: 0.0 ± 0.0
0.0TrpLeu: 0.0 ± 0.0
0.0TrpMet: 0.0 ± 0.0
0.0TrpAsn: 0.0 ± 0.0
0.0TrpPro: 0.0 ± 0.0
1.036TrpGln: 1.036 ± 1.266
0.0TrpArg: 0.0 ± 0.0
0.0TrpSer: 0.0 ± 0.0
1.036TrpThr: 1.036 ± 0.675
0.0TrpVal: 0.0 ± 0.0
0.0TrpTrp: 0.0 ± 0.0
0.0TrpTyr: 0.0 ± 0.0
0.0TrpXaa: 0.0 ± 0.0
Tyr
0.0TyrAla: 0.0 ± 0.0
2.073TyrCys: 2.073 ± 1.35
3.109TyrAsp: 3.109 ± 1.196
1.036TyrGlu: 1.036 ± 0.675
1.036TyrPhe: 1.036 ± 0.924
2.073TyrGly: 2.073 ± 1.35
1.036TyrHis: 1.036 ± 0.924
1.036TyrIle: 1.036 ± 0.675
2.073TyrLys: 2.073 ± 1.005
1.036TyrLeu: 1.036 ± 1.266
1.036TyrMet: 1.036 ± 0.924
1.036TyrAsn: 1.036 ± 1.164
1.036TyrPro: 1.036 ± 0.924
0.0TyrGln: 0.0 ± 0.0
1.036TyrArg: 1.036 ± 1.266
4.145TyrSer: 4.145 ± 2.325
0.0TyrThr: 0.0 ± 0.0
2.073TyrVal: 2.073 ± 1.35
0.0TyrTrp: 0.0 ± 0.0
0.0TyrTyr: 0.0 ± 0.0
0.0TyrXaa: 0.0 ± 0.0
Xaa
1.036XaaAla: 1.036 ± 0.675
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
1.036XaaLys: 1.036 ± 0.675
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
1.036XaaPro: 1.036 ± 1.164
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
58.031XaaXaa: 58.031 ± 26.295
Statistics based on 4 proteins (966 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski