Amino acid dipepetide frequency for Tacheng Tick Virus 2

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
3.044AlaAla: 3.044 ± 2.546
1.142AlaCys: 1.142 ± 0.48
1.522AlaAsp: 1.522 ± 0.317
2.664AlaGlu: 2.664 ± 0.793
3.805AlaPhe: 3.805 ± 0.313
4.186AlaGly: 4.186 ± 4.934
1.903AlaHis: 1.903 ± 1.113
3.044AlaIle: 3.044 ± 0.323
4.186AlaLys: 4.186 ± 1.11
6.469AlaLeu: 6.469 ± 3.019
3.805AlaMet: 3.805 ± 2.226
2.664AlaAsn: 2.664 ± 1.749
2.283AlaPro: 2.283 ± 0.953
1.522AlaGln: 1.522 ± 0.317
4.947AlaArg: 4.947 ± 0.166
3.044AlaSer: 3.044 ± 0.633
3.425AlaThr: 3.425 ± 0.483
3.044AlaVal: 3.044 ± 0.633
0.761AlaTrp: 0.761 ± 0.32
0.381AlaTyr: 0.381 ± 0.16
0.0AlaXaa: 0.0 ± 0.0
Cys
0.0CysAla: 0.0 ± 0.0
0.381CysCys: 0.381 ± 0.16
0.761CysAsp: 0.761 ± 0.32
1.142CysGlu: 1.142 ± 0.48
0.0CysPhe: 0.0 ± 0.0
1.522CysGly: 1.522 ± 0.317
0.381CysHis: 0.381 ± 0.16
1.522CysIle: 1.522 ± 0.64
0.761CysLys: 0.761 ± 0.32
1.142CysLeu: 1.142 ± 0.48
0.381CysMet: 0.381 ± 0.16
0.0CysAsn: 0.0 ± 0.0
0.381CysPro: 0.381 ± 0.16
0.761CysGln: 0.761 ± 0.32
0.761CysArg: 0.761 ± 0.32
1.142CysSer: 1.142 ± 0.48
3.044CysThr: 3.044 ± 0.633
0.381CysVal: 0.381 ± 0.796
0.381CysTrp: 0.381 ± 0.16
1.522CysTyr: 1.522 ± 0.64
0.0CysXaa: 0.0 ± 0.0
Asp
2.664AspAla: 2.664 ± 0.163
0.381AspCys: 0.381 ± 0.16
4.947AspAsp: 4.947 ± 0.166
2.664AspGlu: 2.664 ± 1.119
0.761AspPhe: 0.761 ± 0.32
1.903AspGly: 1.903 ± 0.8
1.142AspHis: 1.142 ± 0.48
4.947AspIle: 4.947 ± 0.79
1.142AspLys: 1.142 ± 0.48
5.708AspLeu: 5.708 ± 0.47
1.522AspMet: 1.522 ± 0.64
1.903AspAsn: 1.903 ± 0.157
3.805AspPro: 3.805 ± 1.269
2.283AspGln: 2.283 ± 0.003
1.903AspArg: 1.903 ± 0.157
3.805AspSer: 3.805 ± 0.643
1.903AspThr: 1.903 ± 0.157
7.991AspVal: 7.991 ± 3.358
0.761AspTrp: 0.761 ± 0.32
2.283AspTyr: 2.283 ± 0.959
0.0AspXaa: 0.0 ± 0.0
Glu
5.327GluAla: 5.327 ± 1.586
0.761GluCys: 0.761 ± 0.32
4.947GluAsp: 4.947 ± 0.166
4.947GluGlu: 4.947 ± 0.166
2.283GluPhe: 2.283 ± 0.003
5.327GluGly: 5.327 ± 0.326
1.903GluHis: 1.903 ± 0.8
3.805GluIle: 3.805 ± 0.313
5.708GluLys: 5.708 ± 1.426
4.566GluLeu: 4.566 ± 0.963
1.522GluMet: 1.522 ± 0.317
0.761GluAsn: 0.761 ± 0.32
3.044GluPro: 3.044 ± 0.323
2.283GluGln: 2.283 ± 0.959
2.664GluArg: 2.664 ± 1.119
4.186GluSer: 4.186 ± 1.759
6.469GluThr: 6.469 ± 1.106
4.566GluVal: 4.566 ± 0.007
0.0GluTrp: 0.0 ± 0.0
2.283GluTyr: 2.283 ± 0.959
0.0GluXaa: 0.0 ± 0.0
Phe
0.761PheAla: 0.761 ± 0.32
0.761PheCys: 0.761 ± 0.32
2.283PheAsp: 2.283 ± 0.003
1.903PheGlu: 1.903 ± 0.8
1.903PhePhe: 1.903 ± 0.8
2.283PheGly: 2.283 ± 0.959
2.664PheHis: 2.664 ± 1.119
1.142PheIle: 1.142 ± 0.48
3.805PheLys: 3.805 ± 0.643
4.186PheLeu: 4.186 ± 0.803
1.903PheMet: 1.903 ± 0.8
2.664PheAsn: 2.664 ± 0.163
2.283PhePro: 2.283 ± 0.959
2.283PheGln: 2.283 ± 0.953
1.903PheArg: 1.903 ± 0.8
1.522PheSer: 1.522 ± 1.273
1.142PheThr: 1.142 ± 0.48
3.044PheVal: 3.044 ± 0.633
0.381PheTrp: 0.381 ± 0.16
0.381PheTyr: 0.381 ± 0.16
0.0PheXaa: 0.0 ± 0.0
Gly
4.566GlyAla: 4.566 ± 3.818
0.761GlyCys: 0.761 ± 0.32
1.522GlyAsp: 1.522 ± 0.64
3.805GlyGlu: 3.805 ± 1.269
4.186GlyPhe: 4.186 ± 0.153
9.132GlyGly: 9.132 ± 13.374
0.381GlyHis: 0.381 ± 0.16
3.425GlyIle: 3.425 ± 1.429
4.566GlyLys: 4.566 ± 1.906
3.805GlyLeu: 3.805 ± 0.313
1.142GlyMet: 1.142 ± 0.419
1.522GlyAsn: 1.522 ± 0.317
5.708GlyPro: 5.708 ± 3.339
3.425GlyGln: 3.425 ± 0.473
6.088GlyArg: 6.088 ± 1.266
4.186GlySer: 4.186 ± 2.066
4.947GlyThr: 4.947 ± 0.166
3.425GlyVal: 3.425 ± 1.439
0.381GlyTrp: 0.381 ± 0.16
1.522GlyTyr: 1.522 ± 0.64
0.0GlyXaa: 0.0 ± 0.0
His
1.522HisAla: 1.522 ± 1.273
1.142HisCys: 1.142 ± 0.48
1.903HisAsp: 1.903 ± 0.8
1.522HisGlu: 1.522 ± 0.317
1.142HisPhe: 1.142 ± 0.48
1.522HisGly: 1.522 ± 0.64
1.522HisHis: 1.522 ± 0.64
2.283HisIle: 2.283 ± 0.959
1.522HisLys: 1.522 ± 0.64
2.664HisLeu: 2.664 ± 1.119
0.761HisMet: 0.761 ± 0.636
0.761HisAsn: 0.761 ± 0.32
1.903HisPro: 1.903 ± 0.8
0.381HisGln: 0.381 ± 0.16
1.522HisArg: 1.522 ± 0.64
0.761HisSer: 0.761 ± 0.32
2.664HisThr: 2.664 ± 0.163
1.522HisVal: 1.522 ± 0.64
0.0HisTrp: 0.0 ± 0.0
0.381HisTyr: 0.381 ± 0.16
0.0HisXaa: 0.0 ± 0.0
Ile
2.283IleAla: 2.283 ± 0.959
0.381IleCys: 0.381 ± 0.16
2.283IleAsp: 2.283 ± 0.003
3.044IleGlu: 3.044 ± 0.323
0.761IlePhe: 0.761 ± 0.32
3.044IleGly: 3.044 ± 0.323
0.0IleHis: 0.0 ± 0.0
2.283IleIle: 2.283 ± 0.959
4.186IleLys: 4.186 ± 0.803
5.708IleLeu: 5.708 ± 0.486
1.142IleMet: 1.142 ± 0.48
3.044IleAsn: 3.044 ± 0.323
3.044IlePro: 3.044 ± 0.323
1.903IleGln: 1.903 ± 0.157
3.425IleArg: 3.425 ± 2.386
3.425IleSer: 3.425 ± 0.483
3.425IleThr: 3.425 ± 0.473
3.805IleVal: 3.805 ± 0.313
0.381IleTrp: 0.381 ± 0.16
0.761IleTyr: 0.761 ± 0.32
0.0IleXaa: 0.0 ± 0.0
Lys
4.566LysAla: 4.566 ± 0.963
0.381LysCys: 0.381 ± 0.16
5.708LysAsp: 5.708 ± 0.486
3.425LysGlu: 3.425 ± 0.483
2.664LysPhe: 2.664 ± 1.119
3.425LysGly: 3.425 ± 2.386
0.761LysHis: 0.761 ± 0.32
2.664LysIle: 2.664 ± 1.119
6.849LysLys: 6.849 ± 0.966
5.708LysLeu: 5.708 ± 1.443
3.805LysMet: 3.805 ± 0.313
3.425LysAsn: 3.425 ± 0.473
4.186LysPro: 4.186 ± 1.11
2.283LysGln: 2.283 ± 0.953
3.044LysArg: 3.044 ± 0.633
2.283LysSer: 2.283 ± 0.959
4.947LysThr: 4.947 ± 1.123
2.664LysVal: 2.664 ± 0.163
1.903LysTrp: 1.903 ± 0.157
1.142LysTyr: 1.142 ± 0.48
0.0LysXaa: 0.0 ± 0.0
Leu
6.469LeuAla: 6.469 ± 2.063
1.903LeuCys: 1.903 ± 0.8
3.425LeuAsp: 3.425 ± 1.439
6.849LeuGlu: 6.849 ± 0.966
3.425LeuPhe: 3.425 ± 0.473
4.566LeuGly: 4.566 ± 0.007
4.566LeuHis: 4.566 ± 1.919
3.425LeuIle: 3.425 ± 0.483
6.469LeuLys: 6.469 ± 1.762
7.61LeuLeu: 7.61 ± 0.33
3.425LeuMet: 3.425 ± 0.483
2.664LeuAsn: 2.664 ± 0.793
3.044LeuPro: 3.044 ± 0.323
4.186LeuGln: 4.186 ± 0.803
6.469LeuArg: 6.469 ± 0.806
6.849LeuSer: 6.849 ± 0.966
5.708LeuThr: 5.708 ± 0.486
6.469LeuVal: 6.469 ± 2.063
1.142LeuTrp: 1.142 ± 0.48
2.664LeuTyr: 2.664 ± 0.793
0.0LeuXaa: 0.0 ± 0.0
Met
0.761MetAla: 0.761 ± 0.32
0.761MetCys: 0.761 ± 0.636
3.425MetAsp: 3.425 ± 1.429
1.903MetGlu: 1.903 ± 0.8
0.381MetPhe: 0.381 ± 0.16
1.903MetGly: 1.903 ± 0.157
0.761MetHis: 0.761 ± 0.32
1.142MetIle: 1.142 ± 0.476
2.283MetLys: 2.283 ± 0.003
3.425MetLeu: 3.425 ± 0.483
0.381MetMet: 0.381 ± 0.16
1.903MetAsn: 1.903 ± 0.157
1.903MetPro: 1.903 ± 0.157
1.903MetGln: 1.903 ± 0.157
3.044MetArg: 3.044 ± 0.323
2.283MetSer: 2.283 ± 0.953
0.0MetThr: 0.0 ± 0.0
2.283MetVal: 2.283 ± 0.959
0.381MetTrp: 0.381 ± 0.16
0.381MetTyr: 0.381 ± 0.16
0.0MetXaa: 0.0 ± 0.0
Asn
2.283AsnAla: 2.283 ± 0.003
1.142AsnCys: 1.142 ± 0.48
1.522AsnAsp: 1.522 ± 0.64
3.425AsnGlu: 3.425 ± 0.483
1.522AsnPhe: 1.522 ± 0.64
2.283AsnGly: 2.283 ± 0.003
0.381AsnHis: 0.381 ± 0.16
2.283AsnIle: 2.283 ± 0.959
2.664AsnLys: 2.664 ± 1.119
4.566AsnLeu: 4.566 ± 1.919
0.381AsnMet: 0.381 ± 1.197
1.142AsnAsn: 1.142 ± 0.48
2.283AsnPro: 2.283 ± 0.953
1.522AsnGln: 1.522 ± 0.317
2.283AsnArg: 2.283 ± 0.953
3.425AsnSer: 3.425 ± 0.483
3.044AsnThr: 3.044 ± 1.589
2.283AsnVal: 2.283 ± 0.959
0.761AsnTrp: 0.761 ± 0.32
0.761AsnTyr: 0.761 ± 0.636
0.0AsnXaa: 0.0 ± 0.0
Pro
4.186ProAla: 4.186 ± 3.022
0.381ProCys: 0.381 ± 0.16
4.186ProAsp: 4.186 ± 0.153
5.327ProGlu: 5.327 ± 0.63
3.044ProPhe: 3.044 ± 1.279
3.044ProGly: 3.044 ± 0.633
1.142ProHis: 1.142 ± 0.48
0.761ProIle: 0.761 ± 0.636
1.522ProLys: 1.522 ± 1.273
3.425ProLeu: 3.425 ± 0.473
1.522ProMet: 1.522 ± 0.64
1.522ProAsn: 1.522 ± 0.64
6.088ProPro: 6.088 ± 2.222
1.903ProGln: 1.903 ± 0.8
3.044ProArg: 3.044 ± 2.546
3.805ProSer: 3.805 ± 0.313
2.664ProThr: 2.664 ± 0.163
3.805ProVal: 3.805 ± 3.182
1.142ProTrp: 1.142 ± 0.48
2.283ProTyr: 2.283 ± 0.003
0.0ProXaa: 0.0 ± 0.0
Gln
1.903GlnAla: 1.903 ± 1.113
0.761GlnCys: 0.761 ± 0.32
1.522GlnAsp: 1.522 ± 0.64
2.283GlnGlu: 2.283 ± 0.953
1.142GlnPhe: 1.142 ± 0.48
4.566GlnGly: 4.566 ± 1.906
1.522GlnHis: 1.522 ± 0.317
2.283GlnIle: 2.283 ± 0.003
1.903GlnLys: 1.903 ± 0.8
3.805GlnLeu: 3.805 ± 1.269
0.761GlnMet: 0.761 ± 0.32
1.903GlnAsn: 1.903 ± 0.8
1.903GlnPro: 1.903 ± 0.157
2.283GlnGln: 2.283 ± 0.953
1.522GlnArg: 1.522 ± 0.64
3.044GlnSer: 3.044 ± 0.323
2.664GlnThr: 2.664 ± 1.119
2.664GlnVal: 2.664 ± 1.119
1.142GlnTrp: 1.142 ± 0.476
2.664GlnTyr: 2.664 ± 1.749
0.0GlnXaa: 0.0 ± 0.0
Arg
4.186ArgAla: 4.186 ± 0.153
0.761ArgCys: 0.761 ± 0.636
1.522ArgAsp: 1.522 ± 0.317
4.186ArgGlu: 4.186 ± 1.11
3.044ArgPhe: 3.044 ± 1.279
6.849ArgGly: 6.849 ± 3.815
0.381ArgHis: 0.381 ± 0.16
2.283ArgIle: 2.283 ± 0.959
4.947ArgLys: 4.947 ± 0.166
3.044ArgLeu: 3.044 ± 0.633
2.283ArgMet: 2.283 ± 0.003
2.283ArgAsn: 2.283 ± 0.959
2.283ArgPro: 2.283 ± 0.959
4.186ArgGln: 4.186 ± 0.153
3.805ArgArg: 3.805 ± 1.269
3.425ArgSer: 3.425 ± 1.429
2.283ArgThr: 2.283 ± 0.959
4.186ArgVal: 4.186 ± 0.153
1.522ArgTrp: 1.522 ± 0.64
1.142ArgTyr: 1.142 ± 0.476
0.0ArgXaa: 0.0 ± 0.0
Ser
3.425SerAla: 3.425 ± 0.473
1.522SerCys: 1.522 ± 1.273
4.566SerAsp: 4.566 ± 0.007
4.186SerGlu: 4.186 ± 0.803
2.664SerPhe: 2.664 ± 0.793
3.044SerGly: 3.044 ± 1.589
1.903SerHis: 1.903 ± 0.157
1.522SerIle: 1.522 ± 0.64
3.044SerLys: 3.044 ± 0.323
7.23SerLeu: 7.23 ± 3.038
1.522SerMet: 1.522 ± 0.64
3.044SerAsn: 3.044 ± 1.279
2.283SerPro: 2.283 ± 0.003
1.903SerGln: 1.903 ± 1.113
3.425SerArg: 3.425 ± 0.483
5.708SerSer: 5.708 ± 1.443
5.708SerThr: 5.708 ± 0.486
4.947SerVal: 4.947 ± 1.123
1.903SerTrp: 1.903 ± 0.8
1.142SerTyr: 1.142 ± 0.48
0.0SerXaa: 0.0 ± 0.0
Thr
2.664ThrAla: 2.664 ± 1.749
0.381ThrCys: 0.381 ± 0.16
3.805ThrAsp: 3.805 ± 1.599
4.566ThrGlu: 4.566 ± 0.963
2.283ThrPhe: 2.283 ± 0.003
3.425ThrGly: 3.425 ± 0.473
2.283ThrHis: 2.283 ± 0.959
4.566ThrIle: 4.566 ± 0.007
5.327ThrLys: 5.327 ± 1.283
6.088ThrLeu: 6.088 ± 1.602
1.522ThrMet: 1.522 ± 1.273
3.425ThrAsn: 3.425 ± 0.473
3.044ThrPro: 3.044 ± 0.633
2.283ThrGln: 2.283 ± 0.003
2.664ThrArg: 2.664 ± 0.793
2.283ThrSer: 2.283 ± 0.959
4.186ThrThr: 4.186 ± 1.759
4.186ThrVal: 4.186 ± 0.153
0.761ThrTrp: 0.761 ± 0.32
1.903ThrTyr: 1.903 ± 1.113
0.0ThrXaa: 0.0 ± 0.0
Val
6.469ValAla: 6.469 ± 3.019
1.142ValCys: 1.142 ± 0.48
2.664ValAsp: 2.664 ± 1.119
4.566ValGlu: 4.566 ± 0.007
2.283ValPhe: 2.283 ± 0.959
3.044ValGly: 3.044 ± 1.279
1.903ValHis: 1.903 ± 0.157
2.283ValIle: 2.283 ± 0.953
3.805ValLys: 3.805 ± 0.643
7.61ValLeu: 7.61 ± 0.627
0.761ValMet: 0.761 ± 0.32
3.805ValAsn: 3.805 ± 0.643
3.425ValPro: 3.425 ± 2.386
3.044ValGln: 3.044 ± 1.279
3.425ValArg: 3.425 ± 0.473
6.849ValSer: 6.849 ± 2.878
1.522ValThr: 1.522 ± 1.273
4.566ValVal: 4.566 ± 1.919
1.142ValTrp: 1.142 ± 0.48
3.044ValTyr: 3.044 ± 1.279
0.0ValXaa: 0.0 ± 0.0
Trp
0.761TrpAla: 0.761 ± 0.636
1.142TrpCys: 1.142 ± 0.48
0.761TrpAsp: 0.761 ± 0.32
2.283TrpGlu: 2.283 ± 0.959
1.142TrpPhe: 1.142 ± 0.48
2.283TrpGly: 2.283 ± 0.003
0.381TrpHis: 0.381 ± 0.16
0.0TrpIle: 0.0 ± 0.0
0.381TrpLys: 0.381 ± 0.16
1.522TrpLeu: 1.522 ± 0.64
0.761TrpMet: 0.761 ± 0.32
1.142TrpAsn: 1.142 ± 0.48
0.0TrpPro: 0.0 ± 0.0
0.761TrpGln: 0.761 ± 0.32
0.381TrpArg: 0.381 ± 0.16
0.0TrpSer: 0.0 ± 0.0
0.381TrpThr: 0.381 ± 0.16
0.761TrpVal: 0.761 ± 0.32
0.761TrpTrp: 0.761 ± 0.636
0.381TrpTyr: 0.381 ± 0.16
0.0TrpXaa: 0.0 ± 0.0
Tyr
0.0TyrAla: 0.0 ± 0.0
0.381TyrCys: 0.381 ± 0.16
1.142TyrAsp: 1.142 ± 0.48
2.664TyrGlu: 2.664 ± 0.163
0.761TyrPhe: 0.761 ± 0.32
1.142TyrGly: 1.142 ± 0.476
1.522TyrHis: 1.522 ± 0.64
2.664TyrIle: 2.664 ± 0.163
0.761TyrLys: 0.761 ± 0.636
3.044TyrLeu: 3.044 ± 0.633
1.522TyrMet: 1.522 ± 0.64
0.761TyrAsn: 0.761 ± 0.32
1.903TyrPro: 1.903 ± 1.113
1.142TyrGln: 1.142 ± 1.433
2.283TyrArg: 2.283 ± 0.959
2.664TyrSer: 2.664 ± 1.119
1.522TyrThr: 1.522 ± 0.64
0.761TyrVal: 0.761 ± 0.32
0.381TyrTrp: 0.381 ± 0.16
0.0TyrTyr: 0.0 ± 0.0
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 2 proteins (2629 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski