Amino acid dipepetide frequency for Blackfly microvirus SF02

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
7.037AlaAla: 7.037 ± 3.35
0.704AlaCys: 0.704 ± 0.441
4.926AlaAsp: 4.926 ± 1.043
7.037AlaGlu: 7.037 ± 1.822
2.111AlaPhe: 2.111 ± 0.874
4.926AlaGly: 4.926 ± 1.076
1.407AlaHis: 1.407 ± 0.568
1.407AlaIle: 1.407 ± 1.024
3.519AlaLys: 3.519 ± 1.542
4.926AlaLeu: 4.926 ± 1.309
1.407AlaMet: 1.407 ± 0.801
2.815AlaAsn: 2.815 ± 1.097
2.815AlaPro: 2.815 ± 0.901
9.852AlaGln: 9.852 ± 3.611
7.037AlaArg: 7.037 ± 1.567
9.148AlaSer: 9.148 ± 2.589
5.63AlaThr: 5.63 ± 2.118
9.852AlaVal: 9.852 ± 2.476
0.0AlaTrp: 0.0 ± 0.0
2.111AlaTyr: 2.111 ± 0.872
0.0AlaXaa: 0.0 ± 0.0
Cys
1.407CysAla: 1.407 ± 0.568
0.0CysCys: 0.0 ± 0.0
1.407CysAsp: 1.407 ± 0.807
0.704CysGlu: 0.704 ± 0.573
0.0CysPhe: 0.0 ± 0.0
0.704CysGly: 0.704 ± 0.573
0.704CysHis: 0.704 ± 0.573
0.704CysIle: 0.704 ± 0.573
1.407CysLys: 1.407 ± 1.145
1.407CysLeu: 1.407 ± 1.145
0.0CysMet: 0.0 ± 0.0
0.0CysAsn: 0.0 ± 0.0
0.704CysPro: 0.704 ± 0.441
0.0CysGln: 0.0 ± 0.0
2.111CysArg: 2.111 ± 0.874
0.704CysSer: 0.704 ± 0.573
0.704CysThr: 0.704 ± 0.441
1.407CysVal: 1.407 ± 1.145
0.0CysTrp: 0.0 ± 0.0
0.0CysTyr: 0.0 ± 0.0
0.0CysXaa: 0.0 ± 0.0
Asp
3.519AspAla: 3.519 ± 0.902
0.0AspCys: 0.0 ± 0.0
1.407AspAsp: 1.407 ± 1.196
2.815AspGlu: 2.815 ± 1.596
2.815AspPhe: 2.815 ± 1.633
2.111AspGly: 2.111 ± 1.043
0.704AspHis: 0.704 ± 0.573
2.111AspIle: 2.111 ± 0.953
1.407AspLys: 1.407 ± 1.196
4.222AspLeu: 4.222 ± 1.233
0.704AspMet: 0.704 ± 0.658
5.63AspAsn: 5.63 ± 1.016
3.519AspPro: 3.519 ± 2.627
0.704AspGln: 0.704 ± 0.441
3.519AspArg: 3.519 ± 1.365
3.519AspSer: 3.519 ± 1.591
4.926AspThr: 4.926 ± 1.499
2.815AspVal: 2.815 ± 1.136
0.0AspTrp: 0.0 ± 0.0
2.111AspTyr: 2.111 ± 1.078
0.0AspXaa: 0.0 ± 0.0
Glu
7.741GluAla: 7.741 ± 3.62
0.704GluCys: 0.704 ± 0.85
0.0GluAsp: 0.0 ± 0.0
2.815GluGlu: 2.815 ± 1.425
4.926GluPhe: 4.926 ± 2.638
0.704GluGly: 0.704 ± 0.85
1.407GluHis: 1.407 ± 0.548
2.815GluIle: 2.815 ± 0.606
3.519GluLys: 3.519 ± 2.119
1.407GluLeu: 1.407 ± 0.568
0.704GluMet: 0.704 ± 0.658
2.111GluAsn: 2.111 ± 1.111
2.815GluPro: 2.815 ± 2.374
3.519GluGln: 3.519 ± 1.183
8.445GluArg: 8.445 ± 3.411
0.704GluSer: 0.704 ± 0.658
2.111GluThr: 2.111 ± 1.545
4.926GluVal: 4.926 ± 2.635
0.0GluTrp: 0.0 ± 0.0
2.815GluTyr: 2.815 ± 1.136
0.0GluXaa: 0.0 ± 0.0
Phe
7.741PheAla: 7.741 ± 1.688
0.0PheCys: 0.0 ± 0.0
5.63PheAsp: 5.63 ± 1.466
1.407PheGlu: 1.407 ± 0.801
3.519PhePhe: 3.519 ± 1.087
7.037PheGly: 7.037 ± 1.74
0.704PheHis: 0.704 ± 0.441
1.407PheIle: 1.407 ± 0.882
0.704PheLys: 0.704 ± 0.85
4.222PheLeu: 4.222 ± 1.499
3.519PheMet: 3.519 ± 1.398
4.222PheAsn: 4.222 ± 1.281
0.0PhePro: 0.0 ± 0.0
2.111PheGln: 2.111 ± 1.289
1.407PheArg: 1.407 ± 0.882
4.926PheSer: 4.926 ± 2.584
2.815PheThr: 2.815 ± 1.097
2.111PheVal: 2.111 ± 1.043
1.407PheTrp: 1.407 ± 1.145
2.111PheTyr: 2.111 ± 0.841
0.0PheXaa: 0.0 ± 0.0
Gly
4.926GlyAla: 4.926 ± 1.377
2.111GlyCys: 2.111 ± 1.718
3.519GlyAsp: 3.519 ± 0.945
4.926GlyGlu: 4.926 ± 1.283
2.111GlyPhe: 2.111 ± 1.323
7.741GlyGly: 7.741 ± 1.781
1.407GlyHis: 1.407 ± 0.807
1.407GlyIle: 1.407 ± 0.568
2.111GlyLys: 2.111 ± 1.078
7.741GlyLeu: 7.741 ± 3.261
2.111GlyMet: 2.111 ± 1.128
2.815GlyAsn: 2.815 ± 1.361
2.815GlyPro: 2.815 ± 1.686
0.0GlyGln: 0.0 ± 0.0
2.111GlyArg: 2.111 ± 1.052
9.148GlySer: 9.148 ± 1.578
5.63GlyThr: 5.63 ± 2.19
2.815GlyVal: 2.815 ± 1.765
0.0GlyTrp: 0.0 ± 0.0
4.926GlyTyr: 4.926 ± 1.866
0.0GlyXaa: 0.0 ± 0.0
His
1.407HisAla: 1.407 ± 0.568
0.704HisCys: 0.704 ± 0.573
1.407HisAsp: 1.407 ± 0.568
0.704HisGlu: 0.704 ± 0.573
0.704HisPhe: 0.704 ± 0.441
2.111HisGly: 2.111 ± 0.872
1.407HisHis: 1.407 ± 0.882
0.0HisIle: 0.0 ± 0.0
0.704HisLys: 0.704 ± 0.441
1.407HisLeu: 1.407 ± 0.568
0.0HisMet: 0.0 ± 0.0
0.704HisAsn: 0.704 ± 0.573
0.704HisPro: 0.704 ± 0.441
1.407HisGln: 1.407 ± 0.568
0.704HisArg: 0.704 ± 0.441
0.704HisSer: 0.704 ± 0.573
0.704HisThr: 0.704 ± 0.441
0.704HisVal: 0.704 ± 0.85
0.0HisTrp: 0.0 ± 0.0
1.407HisTyr: 1.407 ± 1.145
0.0HisXaa: 0.0 ± 0.0
Ile
4.222IleAla: 4.222 ± 1.645
0.0IleCys: 0.0 ± 0.0
1.407IleAsp: 1.407 ± 0.926
1.407IleGlu: 1.407 ± 1.316
0.704IlePhe: 0.704 ± 0.573
4.222IleGly: 4.222 ± 1.094
0.0IleHis: 0.0 ± 0.0
0.704IleIle: 0.704 ± 0.971
0.0IleLys: 0.0 ± 0.0
2.111IleLeu: 2.111 ± 1.349
0.0IleMet: 0.0 ± 0.0
3.519IleAsn: 3.519 ± 1.087
2.111IlePro: 2.111 ± 1.323
1.407IleGln: 1.407 ± 0.882
2.815IleArg: 2.815 ± 2.048
2.111IleSer: 2.111 ± 1.227
2.815IleThr: 2.815 ± 1.151
1.407IleVal: 1.407 ± 0.882
1.407IleTrp: 1.407 ± 0.548
1.407IleTyr: 1.407 ± 0.882
0.0IleXaa: 0.0 ± 0.0
Lys
4.926LysAla: 4.926 ± 2.815
0.0LysCys: 0.0 ± 0.0
0.704LysAsp: 0.704 ± 0.573
2.815LysGlu: 2.815 ± 1.573
0.0LysPhe: 0.0 ± 0.0
2.815LysGly: 2.815 ± 1.081
0.0LysHis: 0.0 ± 0.0
2.815LysIle: 2.815 ± 1.078
3.519LysLys: 3.519 ± 2.864
2.111LysLeu: 2.111 ± 1.227
2.815LysMet: 2.815 ± 1.078
0.704LysAsn: 0.704 ± 0.658
2.815LysPro: 2.815 ± 0.785
0.704LysGln: 0.704 ± 0.658
4.926LysArg: 4.926 ± 1.003
5.63LysSer: 5.63 ± 2.511
3.519LysThr: 3.519 ± 1.234
1.407LysVal: 1.407 ± 1.049
0.0LysTrp: 0.0 ± 0.0
1.407LysTyr: 1.407 ± 1.024
0.0LysXaa: 0.0 ± 0.0
Leu
3.519LeuAla: 3.519 ± 1.118
0.0LeuCys: 0.0 ± 0.0
1.407LeuAsp: 1.407 ± 0.882
2.111LeuGlu: 2.111 ± 0.953
4.222LeuPhe: 4.222 ± 0.909
8.445LeuGly: 8.445 ± 1.713
2.111LeuHis: 2.111 ± 0.841
3.519LeuIle: 3.519 ± 0.945
2.111LeuLys: 2.111 ± 0.556
7.037LeuLeu: 7.037 ± 1.602
2.815LeuMet: 2.815 ± 2.002
6.334LeuAsn: 6.334 ± 2.293
6.334LeuPro: 6.334 ± 2.152
0.704LeuGln: 0.704 ± 0.441
6.334LeuArg: 6.334 ± 1.952
3.519LeuSer: 3.519 ± 1.497
3.519LeuThr: 3.519 ± 1.409
4.222LeuVal: 4.222 ± 1.704
1.407LeuTrp: 1.407 ± 1.145
2.111LeuTyr: 2.111 ± 0.841
0.0LeuXaa: 0.0 ± 0.0
Met
0.0MetAla: 0.0 ± 0.0
0.0MetCys: 0.0 ± 0.0
2.111MetAsp: 2.111 ± 0.747
2.111MetGlu: 2.111 ± 0.953
2.111MetPhe: 2.111 ± 1.128
3.519MetGly: 3.519 ± 1.032
0.0MetHis: 0.0 ± 0.0
0.704MetIle: 0.704 ± 0.971
2.111MetLys: 2.111 ± 1.111
0.0MetLeu: 0.0 ± 0.0
0.704MetMet: 0.704 ± 0.658
0.704MetAsn: 0.704 ± 0.85
0.704MetPro: 0.704 ± 0.441
1.407MetGln: 1.407 ± 1.316
2.815MetArg: 2.815 ± 0.785
4.222MetSer: 4.222 ± 2.371
0.704MetThr: 0.704 ± 0.658
0.704MetVal: 0.704 ± 0.441
1.407MetTrp: 1.407 ± 0.548
0.704MetTyr: 0.704 ± 0.85
0.0MetXaa: 0.0 ± 0.0
Asn
1.407AsnAla: 1.407 ± 0.926
0.704AsnCys: 0.704 ± 0.573
3.519AsnAsp: 3.519 ± 1.918
1.407AsnGlu: 1.407 ± 1.049
1.407AsnPhe: 1.407 ± 0.882
1.407AsnGly: 1.407 ± 0.807
0.704AsnHis: 0.704 ± 0.573
2.815AsnIle: 2.815 ± 1.097
2.111AsnLys: 2.111 ± 1.718
7.037AsnLeu: 7.037 ± 3.047
0.704AsnMet: 0.704 ± 0.85
0.0AsnAsn: 0.0 ± 0.0
3.519AsnPro: 3.519 ± 0.902
2.111AsnGln: 2.111 ± 1.043
4.222AsnArg: 4.222 ± 0.83
3.519AsnSer: 3.519 ± 1.167
2.815AsnThr: 2.815 ± 1.966
1.407AsnVal: 1.407 ± 0.882
0.0AsnTrp: 0.0 ± 0.0
1.407AsnTyr: 1.407 ± 0.882
0.0AsnXaa: 0.0 ± 0.0
Pro
8.445ProAla: 8.445 ± 2.702
0.704ProCys: 0.704 ± 0.573
2.111ProAsp: 2.111 ± 1.323
4.222ProGlu: 4.222 ± 1.466
2.815ProPhe: 2.815 ± 0.998
4.926ProGly: 4.926 ± 1.088
0.704ProHis: 0.704 ± 0.573
3.519ProIle: 3.519 ± 1.167
0.0ProLys: 0.0 ± 0.0
2.815ProLeu: 2.815 ± 1.136
1.407ProMet: 1.407 ± 0.843
0.704ProAsn: 0.704 ± 0.441
7.037ProPro: 7.037 ± 5.38
3.519ProGln: 3.519 ± 1.735
2.815ProArg: 2.815 ± 1.852
4.222ProSer: 4.222 ± 2.209
2.815ProThr: 2.815 ± 0.785
7.037ProVal: 7.037 ± 2.215
0.704ProTrp: 0.704 ± 0.441
0.704ProTyr: 0.704 ± 0.441
0.0ProXaa: 0.0 ± 0.0
Gln
4.222GlnAla: 4.222 ± 1.32
1.407GlnCys: 1.407 ± 1.024
3.519GlnAsp: 3.519 ± 1.183
2.111GlnGlu: 2.111 ± 1.043
2.815GlnPhe: 2.815 ± 1.361
2.111GlnGly: 2.111 ± 1.043
0.0GlnHis: 0.0 ± 0.0
2.111GlnIle: 2.111 ± 0.747
2.111GlnLys: 2.111 ± 0.747
1.407GlnLeu: 1.407 ± 0.807
1.407GlnMet: 1.407 ± 1.049
2.111GlnAsn: 2.111 ± 1.323
1.407GlnPro: 1.407 ± 0.882
3.519GlnGln: 3.519 ± 1.647
2.111GlnArg: 2.111 ± 1.974
2.111GlnSer: 2.111 ± 0.747
3.519GlnThr: 3.519 ± 1.647
2.815GlnVal: 2.815 ± 1.097
1.407GlnTrp: 1.407 ± 0.568
0.704GlnTyr: 0.704 ± 0.658
0.0GlnXaa: 0.0 ± 0.0
Arg
4.222ArgAla: 4.222 ± 1.006
4.926ArgCys: 4.926 ± 2.145
4.926ArgAsp: 4.926 ± 1.135
5.63ArgGlu: 5.63 ± 2.851
7.037ArgPhe: 7.037 ± 2.05
2.815ArgGly: 2.815 ± 0.606
1.407ArgHis: 1.407 ± 0.882
2.815ArgIle: 2.815 ± 1.435
2.815ArgLys: 2.815 ± 1.172
2.815ArgLeu: 2.815 ± 1.216
2.111ArgMet: 2.111 ± 0.751
0.0ArgAsn: 0.0 ± 0.0
5.63ArgPro: 5.63 ± 1.842
4.222ArgGln: 4.222 ± 0.534
2.815ArgArg: 2.815 ± 1.596
10.556ArgSer: 10.556 ± 2.162
1.407ArgThr: 1.407 ± 1.024
2.111ArgVal: 2.111 ± 1.052
0.0ArgTrp: 0.0 ± 0.0
2.815ArgTyr: 2.815 ± 0.785
0.0ArgXaa: 0.0 ± 0.0
Ser
10.556SerAla: 10.556 ± 2.579
0.704SerCys: 0.704 ± 0.573
2.815SerAsp: 2.815 ± 1.415
5.63SerGlu: 5.63 ± 2.637
4.926SerPhe: 4.926 ± 1.931
3.519SerGly: 3.519 ± 1.303
1.407SerHis: 1.407 ± 0.882
1.407SerIle: 1.407 ± 0.882
6.334SerLys: 6.334 ± 2.817
10.556SerLeu: 10.556 ± 1.407
1.407SerMet: 1.407 ± 1.316
2.111SerAsn: 2.111 ± 0.872
4.222SerPro: 4.222 ± 0.866
2.111SerGln: 2.111 ± 0.556
4.926SerArg: 4.926 ± 2.244
5.63SerSer: 5.63 ± 1.792
7.037SerThr: 7.037 ± 2.173
7.037SerVal: 7.037 ± 2.0
2.815SerTrp: 2.815 ± 0.901
0.704SerTyr: 0.704 ± 0.441
0.0SerXaa: 0.0 ± 0.0
Thr
7.741ThrAla: 7.741 ± 2.312
0.0ThrCys: 0.0 ± 0.0
0.704ThrAsp: 0.704 ± 0.573
4.222ThrGlu: 4.222 ± 1.806
6.334ThrPhe: 6.334 ± 2.145
4.926ThrGly: 4.926 ± 3.088
1.407ThrHis: 1.407 ± 0.807
1.407ThrIle: 1.407 ± 0.568
2.111ThrLys: 2.111 ± 1.669
4.222ThrLeu: 4.222 ± 1.284
0.704ThrMet: 0.704 ± 0.78
0.704ThrAsn: 0.704 ± 0.658
6.334ThrPro: 6.334 ± 1.746
2.111ThrGln: 2.111 ± 0.747
4.222ThrArg: 4.222 ± 1.08
7.741ThrSer: 7.741 ± 2.177
6.334ThrThr: 6.334 ± 3.205
0.0ThrVal: 0.0 ± 0.0
0.704ThrTrp: 0.704 ± 0.971
2.111ThrTyr: 2.111 ± 1.052
0.0ThrXaa: 0.0 ± 0.0
Val
2.815ValAla: 2.815 ± 0.608
0.704ValCys: 0.704 ± 0.573
3.519ValAsp: 3.519 ± 1.714
1.407ValGlu: 1.407 ± 1.049
5.63ValPhe: 5.63 ± 1.881
0.704ValGly: 0.704 ± 0.441
0.704ValHis: 0.704 ± 0.573
2.111ValIle: 2.111 ± 1.289
4.926ValLys: 4.926 ± 2.642
4.222ValLeu: 4.222 ± 0.866
1.407ValMet: 1.407 ± 0.568
3.519ValAsn: 3.519 ± 1.945
4.926ValPro: 4.926 ± 2.547
1.407ValGln: 1.407 ± 0.801
4.926ValArg: 4.926 ± 1.98
5.63ValSer: 5.63 ± 0.59
3.519ValThr: 3.519 ± 1.365
4.926ValVal: 4.926 ± 2.628
0.704ValTrp: 0.704 ± 0.441
2.815ValTyr: 2.815 ± 1.136
0.0ValXaa: 0.0 ± 0.0
Trp
0.704TrpAla: 0.704 ± 0.573
0.0TrpCys: 0.0 ± 0.0
0.704TrpAsp: 0.704 ± 0.971
0.0TrpGlu: 0.0 ± 0.0
0.704TrpPhe: 0.704 ± 0.441
2.815TrpGly: 2.815 ± 1.172
0.704TrpHis: 0.704 ± 0.441
0.0TrpIle: 0.0 ± 0.0
0.0TrpLys: 0.0 ± 0.0
0.0TrpLeu: 0.0 ± 0.0
0.0TrpMet: 0.0 ± 0.0
0.704TrpAsn: 0.704 ± 0.441
2.111TrpPro: 2.111 ± 0.747
0.0TrpGln: 0.0 ± 0.0
2.111TrpArg: 2.111 ± 0.556
0.704TrpSer: 0.704 ± 0.441
1.407TrpThr: 1.407 ± 0.568
0.0TrpVal: 0.0 ± 0.0
0.0TrpTrp: 0.0 ± 0.0
0.0TrpTyr: 0.0 ± 0.0
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.111TyrAla: 2.111 ± 0.662
0.704TyrCys: 0.704 ± 0.573
2.815TyrAsp: 2.815 ± 1.573
0.704TyrGlu: 0.704 ± 0.441
2.111TyrPhe: 2.111 ± 1.043
2.815TyrGly: 2.815 ± 1.136
0.704TyrHis: 0.704 ± 0.573
0.0TyrIle: 0.0 ± 0.0
2.111TyrLys: 2.111 ± 0.747
2.111TyrLeu: 2.111 ± 1.043
2.111TyrMet: 2.111 ± 1.323
2.815TyrAsn: 2.815 ± 1.136
0.704TyrPro: 0.704 ± 0.441
2.111TyrGln: 2.111 ± 0.747
1.407TyrArg: 1.407 ± 0.882
1.407TyrSer: 1.407 ± 0.926
2.111TyrThr: 2.111 ± 0.841
2.815TyrVal: 2.815 ± 1.151
0.704TyrTrp: 0.704 ± 0.441
0.704TyrTyr: 0.704 ± 0.573
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 5 proteins (1422 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski