Amino acid dipepetide frequency for Didymella rabiei (Chickpea ascochyta blight fungus) (Mycosphaerella rabiei)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	10.213AlaAla: 10.213 ± 0.071	1.034AlaCys: 1.034 ± 0.014	4.702AlaAsp: 4.702 ± 0.035	5.406AlaGlu: 5.406 ± 0.045	3.236AlaPhe: 3.236 ± 0.028	6.16AlaGly: 6.16 ± 0.04	2.122AlaHis: 2.122 ± 0.022	4.17AlaIle: 4.17 ± 0.033	4.343AlaLys: 4.343 ± 0.033	8.168AlaLeu: 8.168 ± 0.049	2.039AlaMet: 2.039 ± 0.019	3.183AlaAsn: 3.183 ± 0.027	5.75AlaPro: 5.75 ± 0.054	3.879AlaGln: 3.879 ± 0.033	5.296AlaArg: 5.296 ± 0.037	7.858AlaSer: 7.858 ± 0.049	5.768AlaThr: 5.768 ± 0.04	5.684AlaVal: 5.684 ± 0.036	1.224AlaTrp: 1.224 ± 0.015	2.314AlaTyr: 2.314 ± 0.021	0.0AlaXaa: 0.0 ± 0.0
Cys	0.95CysAla: 0.95 ± 0.013	0.216CysCys: 0.216 ± 0.006	0.618CysAsp: 0.618 ± 0.011	0.585CysGlu: 0.585 ± 0.011	0.487CysPhe: 0.487 ± 0.011	0.899CysGly: 0.899 ± 0.016	0.295CysHis: 0.295 ± 0.007	0.639CysIle: 0.639 ± 0.013	0.496CysLys: 0.496 ± 0.011	1.09CysLeu: 1.09 ± 0.014	0.256CysMet: 0.256 ± 0.007	0.424CysAsn: 0.424 ± 0.009	0.602CysPro: 0.602 ± 0.013	0.401CysGln: 0.401 ± 0.009	0.668CysArg: 0.668 ± 0.011	0.833CysSer: 0.833 ± 0.014	0.729CysThr: 0.729 ± 0.013	0.761CysVal: 0.761 ± 0.013	0.181CysTrp: 0.181 ± 0.006	0.328CysTyr: 0.328 ± 0.009	0.0CysXaa: 0.0 ± 0.0
Asp	5.433AspAla: 5.433 ± 0.036	0.608AspCys: 0.608 ± 0.011	4.517AspAsp: 4.517 ± 0.049	4.478AspGlu: 4.478 ± 0.04	2.206AspPhe: 2.206 ± 0.021	4.01AspGly: 4.01 ± 0.033	1.27AspHis: 1.27 ± 0.018	2.831AspIle: 2.831 ± 0.025	2.462AspLys: 2.462 ± 0.027	4.915AspLeu: 4.915 ± 0.035	1.328AspMet: 1.328 ± 0.018	1.856AspAsn: 1.856 ± 0.021	3.121AspPro: 3.121 ± 0.027	1.873AspGln: 1.873 ± 0.019	3.117AspArg: 3.117 ± 0.033	3.966AspSer: 3.966 ± 0.037	3.182AspThr: 3.182 ± 0.031	3.961AspVal: 3.961 ± 0.03	0.901AspTrp: 0.901 ± 0.013	1.588AspTyr: 1.588 ± 0.019	0.0AspXaa: 0.0 ± 0.0
Glu	5.567GluAla: 5.567 ± 0.048	0.575GluCys: 0.575 ± 0.012	4.19GluAsp: 4.19 ± 0.041	5.283GluGlu: 5.283 ± 0.058	1.819GluPhe: 1.819 ± 0.018	3.793GluGly: 3.793 ± 0.032	1.56GluHis: 1.56 ± 0.018	2.696GluIle: 2.696 ± 0.024	3.639GluLys: 3.639 ± 0.033	5.192GluLeu: 5.192 ± 0.043	1.407GluMet: 1.407 ± 0.019	2.034GluAsn: 2.034 ± 0.022	2.828GluPro: 2.828 ± 0.04	2.713GluGln: 2.713 ± 0.028	4.08GluArg: 4.08 ± 0.035	3.945GluSer: 3.945 ± 0.035	3.357GluThr: 3.357 ± 0.03	3.541GluVal: 3.541 ± 0.027	0.87GluTrp: 0.87 ± 0.013	1.608GluTyr: 1.608 ± 0.017	0.0GluXaa: 0.0 ± 0.0
Phe	3.268PheAla: 3.268 ± 0.031	0.502PheCys: 0.502 ± 0.011	2.313PheAsp: 2.313 ± 0.023	2.119PheGlu: 2.119 ± 0.022	1.547PhePhe: 1.547 ± 0.025	2.859PheGly: 2.859 ± 0.03	0.865PheHis: 0.865 ± 0.012	1.592PheIle: 1.592 ± 0.024	1.531PheLys: 1.531 ± 0.018	3.197PheLeu: 3.197 ± 0.029	0.729PheMet: 0.729 ± 0.012	1.383PheAsn: 1.383 ± 0.016	1.844PhePro: 1.844 ± 0.021	1.318PheGln: 1.318 ± 0.018	1.822PheArg: 1.822 ± 0.019	2.835PheSer: 2.835 ± 0.025	2.202PheThr: 2.202 ± 0.028	2.385PheVal: 2.385 ± 0.024	0.607PheTrp: 0.607 ± 0.01	1.042PheTyr: 1.042 ± 0.015	0.0PheXaa: 0.0 ± 0.0
Gly	5.738GlyAla: 5.738 ± 0.043	0.846GlyCys: 0.846 ± 0.013	3.592GlyAsp: 3.592 ± 0.026	3.655GlyGlu: 3.655 ± 0.03	2.772GlyPhe: 2.772 ± 0.027	5.828GlyGly: 5.828 ± 0.058	1.652GlyHis: 1.652 ± 0.019	3.348GlyIle: 3.348 ± 0.028	3.46GlyLys: 3.46 ± 0.032	5.966GlyLeu: 5.966 ± 0.039	1.557GlyMet: 1.557 ± 0.019	2.472GlyAsn: 2.472 ± 0.025	3.19GlyPro: 3.19 ± 0.027	2.53GlyGln: 2.53 ± 0.03	4.13GlyArg: 4.13 ± 0.035	5.525GlySer: 5.525 ± 0.04	4.002GlyThr: 4.002 ± 0.031	4.4GlyVal: 4.4 ± 0.034	1.164GlyTrp: 1.164 ± 0.018	2.11GlyTyr: 2.11 ± 0.024	0.0GlyXaa: 0.0 ± 0.0
His	2.244HisAla: 2.244 ± 0.023	0.319HisCys: 0.319 ± 0.009	1.452HisAsp: 1.452 ± 0.019	1.406HisGlu: 1.406 ± 0.018	0.924HisPhe: 0.924 ± 0.014	1.73HisGly: 1.73 ± 0.017	0.897HisHis: 0.897 ± 0.019	1.198HisIle: 1.198 ± 0.015	0.991HisLys: 0.991 ± 0.012	2.263HisLeu: 2.263 ± 0.021	0.499HisMet: 0.499 ± 0.01	0.902HisAsn: 0.902 ± 0.015	1.674HisPro: 1.674 ± 0.02	1.038HisGln: 1.038 ± 0.016	1.546HisArg: 1.546 ± 0.018	1.874HisSer: 1.874 ± 0.022	1.481HisThr: 1.481 ± 0.016	1.572HisVal: 1.572 ± 0.017	0.354HisTrp: 0.354 ± 0.008	0.701HisTyr: 0.701 ± 0.013	0.0HisXaa: 0.0 ± 0.0
Ile	4.323IleAla: 4.323 ± 0.036	0.658IleCys: 0.658 ± 0.01	2.769IleAsp: 2.769 ± 0.023	2.794IleGlu: 2.794 ± 0.028	1.776IlePhe: 1.776 ± 0.022	3.057IleGly: 3.057 ± 0.03	1.104IleHis: 1.104 ± 0.014	2.214IleIle: 2.214 ± 0.026	2.076IleLys: 2.076 ± 0.022	4.041IleLeu: 4.041 ± 0.035	0.948IleMet: 0.948 ± 0.015	1.717IleAsn: 1.717 ± 0.021	2.79IlePro: 2.79 ± 0.025	1.744IleGln: 1.744 ± 0.02	2.525IleArg: 2.525 ± 0.024	3.435IleSer: 3.435 ± 0.029	2.838IleThr: 2.838 ± 0.029	3.14IleVal: 3.14 ± 0.03	0.658IleTrp: 0.658 ± 0.012	1.278IleTyr: 1.278 ± 0.016	0.0IleXaa: 0.0 ± 0.0
Lys	4.452LysAla: 4.452 ± 0.037	0.466LysCys: 0.466 ± 0.01	2.879LysAsp: 2.879 ± 0.026	3.422LysGlu: 3.422 ± 0.033	1.374LysPhe: 1.374 ± 0.019	3.021LysGly: 3.021 ± 0.03	1.224LysHis: 1.224 ± 0.016	2.172LysIle: 2.172 ± 0.021	3.621LysLys: 3.621 ± 0.053	4.088LysLeu: 4.088 ± 0.032	1.023LysMet: 1.023 ± 0.016	1.755LysAsn: 1.755 ± 0.02	2.792LysPro: 2.792 ± 0.027	2.001LysGln: 2.001 ± 0.024	3.465LysArg: 3.465 ± 0.028	3.459LysSer: 3.459 ± 0.032	2.956LysThr: 2.956 ± 0.024	2.747LysVal: 2.747 ± 0.023	0.675LysTrp: 0.675 ± 0.012	1.322LysTyr: 1.322 ± 0.019	0.0LysXaa: 0.0 ± 0.0
Leu	7.978LeuAla: 7.978 ± 0.053	1.108LeuCys: 1.108 ± 0.017	5.191LeuAsp: 5.191 ± 0.034	5.229LeuGlu: 5.229 ± 0.04	3.149LeuPhe: 3.149 ± 0.028	5.769LeuGly: 5.769 ± 0.039	2.312LeuHis: 2.312 ± 0.023	3.634LeuIle: 3.634 ± 0.037	4.108LeuLys: 4.108 ± 0.03	7.976LeuLeu: 7.976 ± 0.059	1.645LeuMet: 1.645 ± 0.017	3.09LeuAsn: 3.09 ± 0.029	5.591LeuPro: 5.591 ± 0.043	3.868LeuGln: 3.868 ± 0.033	5.61LeuArg: 5.61 ± 0.04	7.034LeuSer: 7.034 ± 0.041	4.882LeuThr: 4.882 ± 0.038	5.304LeuVal: 5.304 ± 0.046	1.147LeuTrp: 1.147 ± 0.017	2.267LeuTyr: 2.267 ± 0.021	0.0LeuXaa: 0.0 ± 0.0
Met	2.145MetAla: 2.145 ± 0.023	0.243MetCys: 0.243 ± 0.008	1.202MetAsp: 1.202 ± 0.015	1.182MetGlu: 1.182 ± 0.017	0.738MetPhe: 0.738 ± 0.013	1.405MetGly: 1.405 ± 0.019	0.534MetHis: 0.534 ± 0.011	0.898MetIle: 0.898 ± 0.015	0.989MetLys: 0.989 ± 0.016	1.859MetLeu: 1.859 ± 0.019	0.555MetMet: 0.555 ± 0.01	0.802MetAsn: 0.802 ± 0.013	1.302MetPro: 1.302 ± 0.017	0.91MetGln: 0.91 ± 0.016	1.26MetArg: 1.26 ± 0.016	1.889MetSer: 1.889 ± 0.021	1.254MetThr: 1.254 ± 0.016	1.241MetVal: 1.241 ± 0.016	0.267MetTrp: 0.267 ± 0.007	0.559MetTyr: 0.559 ± 0.011	0.0MetXaa: 0.0 ± 0.0
Asn	3.411AsnAla: 3.411 ± 0.029	0.402AsnCys: 0.402 ± 0.009	2.039AsnAsp: 2.039 ± 0.021	1.989AsnGlu: 1.989 ± 0.022	1.327AsnPhe: 1.327 ± 0.016	2.879AsnGly: 2.879 ± 0.028	0.845AsnHis: 0.845 ± 0.014	1.911AsnIle: 1.911 ± 0.022	1.662AsnLys: 1.662 ± 0.02	3.079AsnLeu: 3.079 ± 0.027	0.841AsnMet: 0.841 ± 0.015	1.551AsnAsn: 1.551 ± 0.025	2.292AsnPro: 2.292 ± 0.024	1.286AsnGln: 1.286 ± 0.021	1.838AsnArg: 1.838 ± 0.02	2.646AsnSer: 2.646 ± 0.022	2.318AsnThr: 2.318 ± 0.022	2.351AsnVal: 2.351 ± 0.02	0.532AsnTrp: 0.532 ± 0.01	1.044AsnTyr: 1.044 ± 0.015	0.0AsnXaa: 0.0 ± 0.0
Pro	6.025ProAla: 6.025 ± 0.058	0.482ProCys: 0.482 ± 0.011	3.113ProAsp: 3.113 ± 0.029	3.586ProGlu: 3.586 ± 0.033	2.008ProPhe: 2.008 ± 0.02	3.758ProGly: 3.758 ± 0.029	1.479ProHis: 1.479 ± 0.017	2.423ProIle: 2.423 ± 0.023	2.742ProLys: 2.742 ± 0.03	4.693ProLeu: 4.693 ± 0.034	1.078ProMet: 1.078 ± 0.015	2.185ProAsn: 2.185 ± 0.021	5.293ProPro: 5.293 ± 0.078	2.626ProGln: 2.626 ± 0.032	3.474ProArg: 3.474 ± 0.035	6.012ProSer: 6.012 ± 0.054	4.47ProThr: 4.47 ± 0.045	3.631ProVal: 3.631 ± 0.035	0.722ProTrp: 0.722 ± 0.012	1.527ProTyr: 1.527 ± 0.019	0.001ProXaa: 0.001 ± 0.0
Gln	3.64GlnAla: 3.64 ± 0.031	0.435GlnCys: 0.435 ± 0.01	2.19GlnAsp: 2.19 ± 0.024	2.354GlnGlu: 2.354 ± 0.024	1.269GlnPhe: 1.269 ± 0.016	2.41GlnGly: 2.41 ± 0.02	1.331GlnHis: 1.331 ± 0.019	1.828GlnIle: 1.828 ± 0.02	2.003GlnLys: 2.003 ± 0.022	3.511GlnLeu: 3.511 ± 0.03	0.882GlnMet: 0.882 ± 0.013	1.567GlnAsn: 1.567 ± 0.022	2.67GlnPro: 2.67 ± 0.032	2.904GlnGln: 2.904 ± 0.07	2.802GlnArg: 2.802 ± 0.029	3.189GlnSer: 3.189 ± 0.031	2.438GlnThr: 2.438 ± 0.024	2.128GlnVal: 2.128 ± 0.02	0.585GlnTrp: 0.585 ± 0.011	1.225GlnTyr: 1.225 ± 0.017	0.0GlnXaa: 0.0 ± 0.0
Arg	5.037ArgAla: 5.037 ± 0.036	0.667ArgCys: 0.667 ± 0.012	3.333ArgAsp: 3.333 ± 0.035	3.714ArgGlu: 3.714 ± 0.032	2.068ArgPhe: 2.068 ± 0.019	3.701ArgGly: 3.701 ± 0.035	1.566ArgHis: 1.566 ± 0.019	2.807ArgIle: 2.807 ± 0.021	3.517ArgLys: 3.517 ± 0.03	5.262ArgLeu: 5.262 ± 0.042	1.313ArgMet: 1.313 ± 0.015	2.232ArgAsn: 2.232 ± 0.02	3.57ArgPro: 3.57 ± 0.031	2.61ArgGln: 2.61 ± 0.028	5.013ArgArg: 5.013 ± 0.051	4.891ArgSer: 4.891 ± 0.045	3.566ArgThr: 3.566 ± 0.028	3.345ArgVal: 3.345 ± 0.026	0.906ArgTrp: 0.906 ± 0.013	1.597ArgTyr: 1.597 ± 0.018	0.0ArgXaa: 0.0 ± 0.0
Ser	7.196SerAla: 7.196 ± 0.042	0.809SerCys: 0.809 ± 0.015	4.119SerAsp: 4.119 ± 0.033	3.995SerGlu: 3.995 ± 0.033	2.885SerPhe: 2.885 ± 0.025	5.38SerGly: 5.38 ± 0.036	1.967SerHis: 1.967 ± 0.023	3.759SerIle: 3.759 ± 0.027	3.747SerLys: 3.747 ± 0.032	6.797SerLeu: 6.797 ± 0.042	1.687SerMet: 1.687 ± 0.02	2.985SerAsn: 2.985 ± 0.026	5.475SerPro: 5.475 ± 0.057	3.168SerGln: 3.168 ± 0.027	4.81SerArg: 4.81 ± 0.043	8.327SerSer: 8.327 ± 0.081	5.971SerThr: 5.971 ± 0.049	4.587SerVal: 4.587 ± 0.032	1.081SerTrp: 1.081 ± 0.013	2.104SerTyr: 2.104 ± 0.023	0.0SerXaa: 0.0 ± 0.0
Thr	5.912ThrAla: 5.912 ± 0.038	0.736ThrCys: 0.736 ± 0.012	3.047ThrAsp: 3.047 ± 0.024	3.15ThrGlu: 3.15 ± 0.027	2.307ThrPhe: 2.307 ± 0.024	4.198ThrGly: 4.198 ± 0.035	1.453ThrHis: 1.453 ± 0.017	3.004ThrIle: 3.004 ± 0.03	2.7ThrLys: 2.7 ± 0.025	5.452ThrLeu: 5.452 ± 0.039	1.219ThrMet: 1.219 ± 0.015	2.215ThrAsn: 2.215 ± 0.022	4.787ThrPro: 4.787 ± 0.051	2.291ThrGln: 2.291 ± 0.025	3.247ThrArg: 3.247 ± 0.029	5.526ThrSer: 5.526 ± 0.046	4.587ThrThr: 4.587 ± 0.055	3.823ThrVal: 3.823 ± 0.031	0.857ThrTrp: 0.857 ± 0.014	1.664ThrTyr: 1.664 ± 0.019	0.0ThrXaa: 0.0 ± 0.0
Val	5.563ValAla: 5.563 ± 0.038	0.772ValCys: 0.772 ± 0.011	3.78ValAsp: 3.78 ± 0.031	4.001ValGlu: 4.001 ± 0.037	2.383ValPhe: 2.383 ± 0.026	4.112ValGly: 4.112 ± 0.035	1.507ValHis: 1.507 ± 0.018	2.707ValIle: 2.707 ± 0.026	2.908ValLys: 2.908 ± 0.026	5.547ValLeu: 5.547 ± 0.04	1.254ValMet: 1.254 ± 0.018	2.135ValAsn: 2.135 ± 0.019	3.645ValPro: 3.645 ± 0.031	2.529ValGln: 2.529 ± 0.02	3.517ValArg: 3.517 ± 0.028	4.555ValSer: 4.555 ± 0.032	3.558ValThr: 3.558 ± 0.035	4.422ValVal: 4.422 ± 0.034	0.875ValTrp: 0.875 ± 0.013	1.693ValTyr: 1.693 ± 0.018	0.0ValXaa: 0.0 ± 0.0
Trp	1.138TrpAla: 1.138 ± 0.016	0.196TrpCys: 0.196 ± 0.007	0.89TrpAsp: 0.89 ± 0.017	0.805TrpGlu: 0.805 ± 0.012	0.526TrpPhe: 0.526 ± 0.01	0.916TrpGly: 0.916 ± 0.016	0.357TrpHis: 0.357 ± 0.007	0.735TrpIle: 0.735 ± 0.014	0.789TrpLys: 0.789 ± 0.012	1.314TrpLeu: 1.314 ± 0.019	0.362TrpMet: 0.362 ± 0.007	0.628TrpAsn: 0.628 ± 0.011	0.616TrpPro: 0.616 ± 0.012	0.579TrpGln: 0.579 ± 0.011	0.931TrpArg: 0.931 ± 0.013	1.06TrpSer: 1.06 ± 0.014	0.929TrpThr: 0.929 ± 0.013	0.848TrpVal: 0.848 ± 0.016	0.269TrpTrp: 0.269 ± 0.007	0.416TrpTyr: 0.416 ± 0.01	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.313TyrAla: 2.313 ± 0.023	0.386TyrCys: 0.386 ± 0.008	1.687TyrAsp: 1.687 ± 0.022	1.541TyrGlu: 1.541 ± 0.019	1.159TyrPhe: 1.159 ± 0.016	2.052TyrGly: 2.052 ± 0.024	0.726TyrHis: 0.726 ± 0.012	1.318TyrIle: 1.318 ± 0.018	1.132TyrLys: 1.132 ± 0.015	2.483TyrLeu: 2.483 ± 0.024	0.611TyrMet: 0.611 ± 0.012	1.127TyrAsn: 1.127 ± 0.017	1.494TyrPro: 1.494 ± 0.02	1.094TyrGln: 1.094 ± 0.017	1.565TyrArg: 1.565 ± 0.018	1.989TyrSer: 1.989 ± 0.022	1.688TyrThr: 1.688 ± 0.021	1.591TyrVal: 1.591 ± 0.018	0.43TyrTrp: 0.43 ± 0.009	0.902TyrTyr: 0.902 ± 0.015	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.001XaaAla: 0.001 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.001XaaPro: 0.001 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.059XaaXaa: 0.059 ± 0.021

Statistics based on 10558 proteins (5395534 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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