Amino acid dipepetide frequency for Kocuria rhizophila (strain ATCC 9341 / DSM 348 / NBRC 103217 / DC2201)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	19.205AlaAla: 19.205 ± 0.229	0.884AlaCys: 0.884 ± 0.034	6.849AlaAsp: 6.849 ± 0.108	7.943AlaGlu: 7.943 ± 0.108	3.268AlaPhe: 3.268 ± 0.069	11.878AlaGly: 11.878 ± 0.15	2.929AlaHis: 2.929 ± 0.058	3.496AlaIle: 3.496 ± 0.077	2.583AlaLys: 2.583 ± 0.071	13.098AlaLeu: 13.098 ± 0.176	2.761AlaMet: 2.761 ± 0.057	1.966AlaAsn: 1.966 ± 0.056	7.264AlaPro: 7.264 ± 0.131	4.781AlaGln: 4.781 ± 0.088	9.669AlaArg: 9.669 ± 0.144	6.666AlaSer: 6.666 ± 0.089	6.815AlaThr: 6.815 ± 0.096	12.146AlaVal: 12.146 ± 0.16	1.739AlaTrp: 1.739 ± 0.055	2.04AlaTyr: 2.04 ± 0.056	0.0AlaXaa: 0.0 ± 0.0
Cys	0.944CysAla: 0.944 ± 0.035	0.079CysCys: 0.079 ± 0.01	0.358CysAsp: 0.358 ± 0.02	0.373CysGlu: 0.373 ± 0.022	0.229CysPhe: 0.229 ± 0.015	0.786CysGly: 0.786 ± 0.036	0.193CysHis: 0.193 ± 0.017	0.211CysIle: 0.211 ± 0.016	0.086CysLys: 0.086 ± 0.011	0.641CysLeu: 0.641 ± 0.032	0.125CysMet: 0.125 ± 0.013	0.129CysAsn: 0.129 ± 0.013	0.409CysPro: 0.409 ± 0.023	0.161CysGln: 0.161 ± 0.015	0.501CysArg: 0.501 ± 0.024	0.44CysSer: 0.44 ± 0.026	0.446CysThr: 0.446 ± 0.027	0.609CysVal: 0.609 ± 0.027	0.093CysTrp: 0.093 ± 0.011	0.16CysTyr: 0.16 ± 0.012	0.0CysXaa: 0.0 ± 0.0
Asp	8.262AspAla: 8.262 ± 0.129	0.3AspCys: 0.3 ± 0.017	3.176AspAsp: 3.176 ± 0.068	4.002AspGlu: 4.002 ± 0.079	1.538AspPhe: 1.538 ± 0.04	5.205AspGly: 5.205 ± 0.083	1.417AspHis: 1.417 ± 0.043	1.821AspIle: 1.821 ± 0.053	1.072AspLys: 1.072 ± 0.043	5.636AspLeu: 5.636 ± 0.09	1.091AspMet: 1.091 ± 0.043	0.878AspAsn: 0.878 ± 0.039	4.649AspPro: 4.649 ± 0.092	1.566AspGln: 1.566 ± 0.048	4.307AspArg: 4.307 ± 0.09	2.703AspSer: 2.703 ± 0.054	3.435AspThr: 3.435 ± 0.063	5.528AspVal: 5.528 ± 0.086	0.807AspTrp: 0.807 ± 0.032	1.241AspTyr: 1.241 ± 0.045	0.0AspXaa: 0.0 ± 0.0
Glu	6.756GluAla: 6.756 ± 0.108	0.363GluCys: 0.363 ± 0.02	4.127GluAsp: 4.127 ± 0.075	3.346GluGlu: 3.346 ± 0.083	1.691GluPhe: 1.691 ± 0.047	4.258GluGly: 4.258 ± 0.078	2.242GluHis: 2.242 ± 0.062	2.619GluIle: 2.619 ± 0.06	1.626GluLys: 1.626 ± 0.056	6.693GluLeu: 6.693 ± 0.096	1.009GluMet: 1.009 ± 0.036	1.661GluAsn: 1.661 ± 0.05	3.201GluPro: 3.201 ± 0.072	2.913GluGln: 2.913 ± 0.066	5.335GluArg: 5.335 ± 0.11	2.911GluSer: 2.911 ± 0.067	3.268GluThr: 3.268 ± 0.066	4.393GluVal: 4.393 ± 0.085	0.755GluTrp: 0.755 ± 0.027	1.162GluTyr: 1.162 ± 0.038	0.0GluXaa: 0.0 ± 0.0
Phe	3.413PheAla: 3.413 ± 0.076	0.237PheCys: 0.237 ± 0.017	1.905PheAsp: 1.905 ± 0.05	1.729PheGlu: 1.729 ± 0.049	1.036PhePhe: 1.036 ± 0.04	2.885PheGly: 2.885 ± 0.076	0.639PheHis: 0.639 ± 0.03	0.942PheIle: 0.942 ± 0.046	0.556PheLys: 0.556 ± 0.03	2.653PheLeu: 2.653 ± 0.07	0.617PheMet: 0.617 ± 0.029	0.661PheAsn: 0.661 ± 0.037	1.367PhePro: 1.367 ± 0.041	0.75PheGln: 0.75 ± 0.029	1.655PheArg: 1.655 ± 0.048	1.746PheSer: 1.746 ± 0.051	2.132PheThr: 2.132 ± 0.05	2.682PheVal: 2.682 ± 0.073	0.422PheTrp: 0.422 ± 0.027	0.634PheTyr: 0.634 ± 0.029	0.0PheXaa: 0.0 ± 0.0
Gly	10.909GlyAla: 10.909 ± 0.136	0.707GlyCys: 0.707 ± 0.033	4.515GlyAsp: 4.515 ± 0.079	5.11GlyGlu: 5.11 ± 0.078	2.977GlyPhe: 2.977 ± 0.064	7.825GlyGly: 7.825 ± 0.152	2.218GlyHis: 2.218 ± 0.058	3.957GlyIle: 3.957 ± 0.07	2.246GlyLys: 2.246 ± 0.052	8.551GlyLeu: 8.551 ± 0.128	2.244GlyMet: 2.244 ± 0.055	1.729GlyAsn: 1.729 ± 0.052	4.601GlyPro: 4.601 ± 0.084	2.89GlyGln: 2.89 ± 0.062	6.572GlyArg: 6.572 ± 0.102	5.892GlySer: 5.892 ± 0.108	6.121GlyThr: 6.121 ± 0.098	7.788GlyVal: 7.788 ± 0.109	1.557GlyTrp: 1.557 ± 0.046	2.19GlyTyr: 2.19 ± 0.052	0.0GlyXaa: 0.0 ± 0.0
His	2.745HisAla: 2.745 ± 0.067	0.17HisCys: 0.17 ± 0.015	1.447HisAsp: 1.447 ± 0.038	1.604HisGlu: 1.604 ± 0.043	0.598HisPhe: 0.598 ± 0.028	2.568HisGly: 2.568 ± 0.062	0.798HisHis: 0.798 ± 0.03	0.619HisIle: 0.619 ± 0.027	0.368HisLys: 0.368 ± 0.023	2.224HisLeu: 2.224 ± 0.053	0.478HisMet: 0.478 ± 0.023	0.396HisAsn: 0.396 ± 0.024	1.933HisPro: 1.933 ± 0.048	0.661HisGln: 0.661 ± 0.03	2.249HisArg: 2.249 ± 0.062	1.123HisSer: 1.123 ± 0.036	1.411HisThr: 1.411 ± 0.039	2.15HisVal: 2.15 ± 0.059	0.349HisTrp: 0.349 ± 0.021	0.484HisTyr: 0.484 ± 0.027	0.0HisXaa: 0.0 ± 0.0
Ile	4.56IleAla: 4.56 ± 0.099	0.242IleCys: 0.242 ± 0.017	2.061IleAsp: 2.061 ± 0.053	2.051IleGlu: 2.051 ± 0.056	1.04IlePhe: 1.04 ± 0.036	3.264IleGly: 3.264 ± 0.065	0.758IleHis: 0.758 ± 0.032	1.184IleIle: 1.184 ± 0.046	0.801IleLys: 0.801 ± 0.039	3.059IleLeu: 3.059 ± 0.078	0.755IleMet: 0.755 ± 0.035	0.852IleAsn: 0.852 ± 0.031	2.041IlePro: 2.041 ± 0.057	0.982IleGln: 0.982 ± 0.034	2.259IleArg: 2.259 ± 0.05	2.002IleSer: 2.002 ± 0.052	2.483IleThr: 2.483 ± 0.062	3.213IleVal: 3.213 ± 0.066	0.303IleTrp: 0.303 ± 0.018	0.606IleTyr: 0.606 ± 0.028	0.0IleXaa: 0.0 ± 0.0
Lys	2.531LysAla: 2.531 ± 0.078	0.103LysCys: 0.103 ± 0.012	1.455LysAsp: 1.455 ± 0.047	1.11LysGlu: 1.11 ± 0.043	0.518LysPhe: 0.518 ± 0.027	1.633LysGly: 1.633 ± 0.049	0.484LysHis: 0.484 ± 0.024	0.987LysIle: 0.987 ± 0.044	0.913LysLys: 0.913 ± 0.041	1.98LysLeu: 1.98 ± 0.049	0.454LysMet: 0.454 ± 0.027	0.654LysAsn: 0.654 ± 0.035	1.194LysPro: 1.194 ± 0.053	0.719LysGln: 0.719 ± 0.032	1.473LysArg: 1.473 ± 0.047	1.127LysSer: 1.127 ± 0.041	1.284LysThr: 1.284 ± 0.046	1.768LysVal: 1.768 ± 0.055	0.232LysTrp: 0.232 ± 0.015	0.494LysTyr: 0.494 ± 0.024	0.0LysXaa: 0.0 ± 0.0
Leu	12.849LeuAla: 12.849 ± 0.166	0.749LeuCys: 0.749 ± 0.031	6.186LeuAsp: 6.186 ± 0.102	5.272LeuGlu: 5.272 ± 0.088	2.6LeuPhe: 2.6 ± 0.078	9.098LeuGly: 9.098 ± 0.122	2.152LeuHis: 2.152 ± 0.057	3.283LeuIle: 3.283 ± 0.077	1.884LeuLys: 1.884 ± 0.049	9.71LeuLeu: 9.71 ± 0.154	1.847LeuMet: 1.847 ± 0.054	2.049LeuAsn: 2.049 ± 0.052	5.516LeuPro: 5.516 ± 0.096	2.615LeuGln: 2.615 ± 0.055	7.46LeuArg: 7.46 ± 0.137	5.897LeuSer: 5.897 ± 0.097	6.279LeuThr: 6.279 ± 0.089	9.137LeuVal: 9.137 ± 0.127	1.296LeuTrp: 1.296 ± 0.044	1.667LeuTyr: 1.667 ± 0.045	0.0LeuXaa: 0.0 ± 0.0
Met	2.615MetAla: 2.615 ± 0.057	0.166MetCys: 0.166 ± 0.013	1.142MetAsp: 1.142 ± 0.042	0.896MetGlu: 0.896 ± 0.038	0.571MetPhe: 0.571 ± 0.032	1.808MetGly: 1.808 ± 0.049	0.425MetHis: 0.425 ± 0.023	0.822MetIle: 0.822 ± 0.032	0.478MetLys: 0.478 ± 0.027	1.991MetLeu: 1.991 ± 0.054	0.401MetMet: 0.401 ± 0.025	0.541MetAsn: 0.541 ± 0.026	1.14MetPro: 1.14 ± 0.04	0.574MetGln: 0.574 ± 0.025	1.401MetArg: 1.401 ± 0.045	1.8MetSer: 1.8 ± 0.051	1.691MetThr: 1.691 ± 0.042	1.677MetVal: 1.677 ± 0.043	0.242MetTrp: 0.242 ± 0.017	0.344MetTyr: 0.344 ± 0.024	0.0MetXaa: 0.0 ± 0.0
Asn	2.362AsnAla: 2.362 ± 0.056	0.121AsnCys: 0.121 ± 0.012	1.034AsnAsp: 1.034 ± 0.042	1.025AsnGlu: 1.025 ± 0.035	0.633AsnPhe: 0.633 ± 0.033	1.935AsnGly: 1.935 ± 0.051	0.469AsnHis: 0.469 ± 0.027	0.812AsnIle: 0.812 ± 0.034	0.483AsnLys: 0.483 ± 0.027	1.958AsnLeu: 1.958 ± 0.051	0.431AsnMet: 0.431 ± 0.024	0.487AsnAsn: 0.487 ± 0.029	1.638AsnPro: 1.638 ± 0.05	0.617AsnGln: 0.617 ± 0.03	1.411AsnArg: 1.411 ± 0.048	1.049AsnSer: 1.049 ± 0.034	1.198AsnThr: 1.198 ± 0.042	1.61AsnVal: 1.61 ± 0.05	0.318AsnTrp: 0.318 ± 0.021	0.46AsnTyr: 0.46 ± 0.024	0.0AsnXaa: 0.0 ± 0.0
Pro	7.655ProAla: 7.655 ± 0.129	0.309ProCys: 0.309 ± 0.024	3.767ProAsp: 3.767 ± 0.07	4.953ProGlu: 4.953 ± 0.092	1.557ProPhe: 1.557 ± 0.049	6.302ProGly: 6.302 ± 0.11	1.471ProHis: 1.471 ± 0.042	1.239ProIle: 1.239 ± 0.049	0.956ProLys: 0.956 ± 0.039	4.711ProLeu: 4.711 ± 0.081	1.007ProMet: 1.007 ± 0.036	0.943ProAsn: 0.943 ± 0.035	2.37ProPro: 2.37 ± 0.066	2.089ProGln: 2.089 ± 0.051	4.267ProArg: 4.267 ± 0.085	3.322ProSer: 3.322 ± 0.071	3.191ProThr: 3.191 ± 0.067	5.589ProVal: 5.589 ± 0.095	0.918ProTrp: 0.918 ± 0.036	1.059ProTyr: 1.059 ± 0.039	0.0ProXaa: 0.0 ± 0.0
Gln	3.576GlnAla: 3.576 ± 0.064	0.185GlnCys: 0.185 ± 0.014	2.267GlnAsp: 2.267 ± 0.059	1.869GlnGlu: 1.869 ± 0.054	0.893GlnPhe: 0.893 ± 0.033	2.562GlnGly: 2.562 ± 0.063	0.889GlnHis: 0.889 ± 0.033	1.253GlnIle: 1.253 ± 0.04	0.835GlnLys: 0.835 ± 0.033	3.561GlnLeu: 3.561 ± 0.073	0.617GlnMet: 0.617 ± 0.027	0.724GlnAsn: 0.724 ± 0.032	1.711GlnPro: 1.711 ± 0.048	1.532GlnGln: 1.532 ± 0.048	2.988GlnArg: 2.988 ± 0.071	1.509GlnSer: 1.509 ± 0.051	1.434GlnThr: 1.434 ± 0.045	2.333GlnVal: 2.333 ± 0.059	0.649GlnTrp: 0.649 ± 0.03	0.755GlnTyr: 0.755 ± 0.031	0.0GlnXaa: 0.0 ± 0.0
Arg	9.39ArgAla: 9.39 ± 0.124	0.531ArgCys: 0.531 ± 0.028	4.31ArgAsp: 4.31 ± 0.083	5.39ArgGlu: 5.39 ± 0.094	2.193ArgPhe: 2.193 ± 0.056	6.138ArgGly: 6.138 ± 0.085	1.855ArgHis: 1.855 ± 0.048	3.054ArgIle: 3.054 ± 0.061	1.541ArgLys: 1.541 ± 0.053	6.66ArgLeu: 6.66 ± 0.111	1.857ArgMet: 1.857 ± 0.047	1.487ArgAsn: 1.487 ± 0.05	4.064ArgPro: 4.064 ± 0.083	2.271ArgGln: 2.271 ± 0.055	6.747ArgArg: 6.747 ± 0.123	4.369ArgSer: 4.369 ± 0.084	4.91ArgThr: 4.91 ± 0.071	6.153ArgVal: 6.153 ± 0.098	1.256ArgTrp: 1.256 ± 0.039	1.485ArgTyr: 1.485 ± 0.039	0.0ArgXaa: 0.0 ± 0.0
Ser	7.058SerAla: 7.058 ± 0.098	0.366SerCys: 0.366 ± 0.023	2.754SerAsp: 2.754 ± 0.055	3.227SerGlu: 3.227 ± 0.075	1.719SerPhe: 1.719 ± 0.046	6.024SerGly: 6.024 ± 0.106	1.364SerHis: 1.364 ± 0.043	1.881SerIle: 1.881 ± 0.048	1.141SerLys: 1.141 ± 0.045	5.098SerLeu: 5.098 ± 0.075	1.389SerMet: 1.389 ± 0.046	1.073SerAsn: 1.073 ± 0.035	3.457SerPro: 3.457 ± 0.071	1.713SerGln: 1.713 ± 0.045	4.124SerArg: 4.124 ± 0.078	3.733SerSer: 3.733 ± 0.083	3.66SerThr: 3.66 ± 0.064	5.011SerVal: 5.011 ± 0.094	0.918SerTrp: 0.918 ± 0.035	1.262SerTyr: 1.262 ± 0.041	0.0SerXaa: 0.0 ± 0.0
Thr	8.091ThrAla: 8.091 ± 0.107	0.382ThrCys: 0.382 ± 0.023	3.548ThrAsp: 3.548 ± 0.074	3.443ThrGlu: 3.443 ± 0.066	1.717ThrPhe: 1.717 ± 0.047	6.458ThrGly: 6.458 ± 0.094	1.272ThrHis: 1.272 ± 0.042	1.779ThrIle: 1.779 ± 0.045	1.07ThrLys: 1.07 ± 0.038	5.325ThrLeu: 5.325 ± 0.087	1.183ThrMet: 1.183 ± 0.034	1.086ThrAsn: 1.086 ± 0.039	4.196ThrPro: 4.196 ± 0.07	1.671ThrGln: 1.671 ± 0.054	4.07ThrArg: 4.07 ± 0.068	3.447ThrSer: 3.447 ± 0.08	3.711ThrThr: 3.711 ± 0.074	6.714ThrVal: 6.714 ± 0.112	0.908ThrTrp: 0.908 ± 0.039	1.115ThrTyr: 1.115 ± 0.037	0.0ThrXaa: 0.0 ± 0.0
Val	11.205ValAla: 11.205 ± 0.123	0.779ValCys: 0.779 ± 0.029	5.587ValAsp: 5.587 ± 0.093	5.075ValGlu: 5.075 ± 0.082	2.655ValPhe: 2.655 ± 0.063	7.02ValGly: 7.02 ± 0.114	2.097ValHis: 2.097 ± 0.042	3.436ValIle: 3.436 ± 0.069	1.785ValLys: 1.785 ± 0.048	10.223ValLeu: 10.223 ± 0.15	1.818ValMet: 1.818 ± 0.052	1.895ValAsn: 1.895 ± 0.055	5.198ValPro: 5.198 ± 0.08	2.48ValGln: 2.48 ± 0.055	6.334ValArg: 6.334 ± 0.085	5.283ValSer: 5.283 ± 0.087	5.754ValThr: 5.754 ± 0.097	9.572ValVal: 9.572 ± 0.143	1.13ValTrp: 1.13 ± 0.04	1.513ValTyr: 1.513 ± 0.046	0.0ValXaa: 0.0 ± 0.0
Trp	1.62TrpAla: 1.62 ± 0.047	0.145TrpCys: 0.145 ± 0.015	0.875TrpAsp: 0.875 ± 0.038	0.719TrpGlu: 0.719 ± 0.026	0.572TrpPhe: 0.572 ± 0.029	1.072TrpGly: 1.072 ± 0.036	0.339TrpHis: 0.339 ± 0.021	0.586TrpIle: 0.586 ± 0.025	0.286TrpLys: 0.286 ± 0.022	1.858TrpLeu: 1.858 ± 0.056	0.272TrpMet: 0.272 ± 0.019	0.414TrpAsn: 0.414 ± 0.021	0.673TrpPro: 0.673 ± 0.032	0.513TrpGln: 0.513 ± 0.028	1.218TrpArg: 1.218 ± 0.039	0.849TrpSer: 0.849 ± 0.032	0.764TrpThr: 0.764 ± 0.036	1.132TrpVal: 1.132 ± 0.045	0.386TrpTrp: 0.386 ± 0.025	0.29TrpTyr: 0.29 ± 0.02	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.235TyrAla: 2.235 ± 0.049	0.153TyrCys: 0.153 ± 0.014	1.268TyrAsp: 1.268 ± 0.042	1.191TyrGlu: 1.191 ± 0.043	0.656TyrPhe: 0.656 ± 0.034	1.879TyrGly: 1.879 ± 0.054	0.364TyrHis: 0.364 ± 0.021	0.537TyrIle: 0.537 ± 0.028	0.402TyrLys: 0.402 ± 0.025	1.92TyrLeu: 1.92 ± 0.05	0.368TyrMet: 0.368 ± 0.023	0.429TyrAsn: 0.429 ± 0.027	1.054TyrPro: 1.054 ± 0.037	0.643TyrGln: 0.643 ± 0.031	1.618TyrArg: 1.618 ± 0.051	1.102TyrSer: 1.102 ± 0.039	1.199TyrThr: 1.199 ± 0.04	1.638TyrVal: 1.638 ± 0.041	0.306TyrTrp: 0.306 ± 0.019	0.48TyrTyr: 0.48 ± 0.026	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 2352 proteins (793120 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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