Amino acid dipepetide frequency for Ryegrass mottle virus

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
8.57AlaAla: 8.57 ± 1.93
2.142AlaCys: 2.142 ± 0.795
5.892AlaAsp: 5.892 ± 1.309
4.285AlaGlu: 4.285 ± 0.877
2.678AlaPhe: 2.678 ± 1.132
8.034AlaGly: 8.034 ± 0.316
1.607AlaHis: 1.607 ± 0.539
2.142AlaIle: 2.142 ± 0.752
3.214AlaLys: 3.214 ± 0.596
3.749AlaLeu: 3.749 ± 1.312
2.678AlaMet: 2.678 ± 1.87
2.142AlaAsn: 2.142 ± 0.752
5.356AlaPro: 5.356 ± 1.186
1.071AlaGln: 1.071 ± 0.613
9.106AlaArg: 9.106 ± 1.107
4.821AlaSer: 4.821 ± 1.711
5.892AlaThr: 5.892 ± 1.065
5.356AlaVal: 5.356 ± 1.836
1.607AlaTrp: 1.607 ± 0.539
1.071AlaTyr: 1.071 ± 0.376
0.0AlaXaa: 0.0 ± 0.0
Cys
0.536CysAla: 0.536 ± 0.326
0.0CysCys: 0.0 ± 0.0
0.536CysAsp: 0.536 ± 0.326
2.142CysGlu: 2.142 ± 2.439
0.0CysPhe: 0.0 ± 0.0
3.214CysGly: 3.214 ± 0.858
0.536CysHis: 0.536 ± 0.326
2.142CysIle: 2.142 ± 0.795
1.071CysLys: 1.071 ± 1.226
1.607CysLeu: 1.607 ± 0.978
0.0CysMet: 0.0 ± 0.0
0.536CysAsn: 0.536 ± 0.326
2.142CysPro: 2.142 ± 1.189
0.536CysGln: 0.536 ± 0.464
1.071CysArg: 1.071 ± 0.652
3.214CysSer: 3.214 ± 1.178
0.536CysThr: 0.536 ± 0.326
1.607CysVal: 1.607 ± 0.779
0.0CysTrp: 0.0 ± 0.0
0.0CysTyr: 0.0 ± 0.0
0.0CysXaa: 0.0 ± 0.0
Asp
2.678AspAla: 2.678 ± 0.859
1.607AspCys: 1.607 ± 2.55
0.536AspAsp: 0.536 ± 0.326
3.214AspGlu: 3.214 ± 0.858
1.607AspPhe: 1.607 ± 0.53
6.427AspGly: 6.427 ± 1.773
0.0AspHis: 0.0 ± 0.0
4.821AspIle: 4.821 ± 0.991
0.536AspLys: 0.536 ± 0.326
4.821AspLeu: 4.821 ± 0.889
1.607AspMet: 1.607 ± 0.53
1.071AspAsn: 1.071 ± 0.652
6.427AspPro: 6.427 ± 1.192
0.536AspGln: 0.536 ± 0.326
1.607AspArg: 1.607 ± 0.779
3.749AspSer: 3.749 ± 1.312
0.0AspThr: 0.0 ± 0.0
4.821AspVal: 4.821 ± 1.486
1.607AspTrp: 1.607 ± 0.53
0.536AspTyr: 0.536 ± 0.326
0.0AspXaa: 0.0 ± 0.0
Glu
6.963GluAla: 6.963 ± 2.234
0.536GluCys: 0.536 ± 0.326
2.678GluAsp: 2.678 ± 1.132
3.749GluGlu: 3.749 ± 0.846
1.071GluPhe: 1.071 ± 0.376
4.285GluGly: 4.285 ± 1.591
0.536GluHis: 0.536 ± 0.689
3.214GluIle: 3.214 ± 1.405
4.285GluLys: 4.285 ± 0.877
6.427GluLeu: 6.427 ± 1.672
2.142GluMet: 2.142 ± 0.795
2.142GluAsn: 2.142 ± 1.225
4.285GluPro: 4.285 ± 0.873
4.285GluGln: 4.285 ± 2.132
4.285GluArg: 4.285 ± 0.962
5.356GluSer: 5.356 ± 1.968
2.678GluThr: 2.678 ± 0.962
4.285GluVal: 4.285 ± 2.593
1.071GluTrp: 1.071 ± 0.376
2.678GluTyr: 2.678 ± 0.608
0.0GluXaa: 0.0 ± 0.0
Phe
1.071PheAla: 1.071 ± 0.376
0.536PheCys: 0.536 ± 0.326
2.142PheAsp: 2.142 ± 0.989
1.071PheGlu: 1.071 ± 1.226
0.536PhePhe: 0.536 ± 0.326
1.607PheGly: 1.607 ± 0.53
1.607PheHis: 1.607 ± 0.53
0.536PheIle: 0.536 ± 0.326
0.536PheLys: 0.536 ± 0.326
1.071PheLeu: 1.071 ± 0.376
0.0PheMet: 0.0 ± 0.0
0.536PheAsn: 0.536 ± 0.689
0.536PhePro: 0.536 ± 1.342
2.142PheGln: 2.142 ± 0.903
1.607PheArg: 1.607 ± 0.978
3.214PheSer: 3.214 ± 1.06
1.607PheThr: 1.607 ± 1.436
0.0PheVal: 0.0 ± 0.0
1.071PheTrp: 1.071 ± 0.376
0.0PheTyr: 0.0 ± 0.0
0.0PheXaa: 0.0 ± 0.0
Gly
3.214GlyAla: 3.214 ± 0.596
0.0GlyCys: 0.0 ± 0.0
5.356GlyAsp: 5.356 ± 0.777
7.499GlyGlu: 7.499 ± 1.929
2.678GlyPhe: 2.678 ± 1.094
2.678GlyGly: 2.678 ± 0.623
2.142GlyHis: 2.142 ± 0.989
0.536GlyIle: 0.536 ± 0.326
7.499GlyLys: 7.499 ± 1.927
6.427GlyLeu: 6.427 ± 1.773
3.214GlyMet: 3.214 ± 1.06
2.678GlyAsn: 2.678 ± 0.623
4.821GlyPro: 4.821 ± 2.57
2.678GlyGln: 2.678 ± 1.753
3.749GlyArg: 3.749 ± 1.14
9.641GlySer: 9.641 ± 0.603
8.57GlyThr: 8.57 ± 2.671
5.892GlyVal: 5.892 ± 1.903
2.678GlyTrp: 2.678 ± 0.859
0.536GlyTyr: 0.536 ± 0.326
0.0GlyXaa: 0.0 ± 0.0
His
2.142HisAla: 2.142 ± 0.473
1.607HisCys: 1.607 ± 1.115
0.536HisAsp: 0.536 ± 1.342
1.071HisGlu: 1.071 ± 0.652
1.071HisPhe: 1.071 ± 0.613
1.071HisGly: 1.071 ± 2.685
1.071HisHis: 1.071 ± 2.685
0.536HisIle: 0.536 ± 1.342
0.0HisLys: 0.0 ± 0.0
0.536HisLeu: 0.536 ± 0.326
0.0HisMet: 0.0 ± 1.072
0.0HisAsn: 0.0 ± 0.0
0.536HisPro: 0.536 ± 0.326
0.536HisGln: 0.536 ± 0.326
2.142HisArg: 2.142 ± 0.752
3.214HisSer: 3.214 ± 0.858
0.0HisThr: 0.0 ± 0.0
1.071HisVal: 1.071 ± 0.376
1.071HisTrp: 1.071 ± 1.226
0.0HisTyr: 0.0 ± 0.0
0.0HisXaa: 0.0 ± 0.0
Ile
3.749IleAla: 3.749 ± 0.731
0.0IleCys: 0.0 ± 0.0
4.821IleAsp: 4.821 ± 1.582
2.678IleGlu: 2.678 ± 1.1
1.607IlePhe: 1.607 ± 1.115
3.749IleGly: 3.749 ± 1.312
1.071IleHis: 1.071 ± 0.376
0.536IleIle: 0.536 ± 0.326
1.071IleLys: 1.071 ± 0.652
1.607IleLeu: 1.607 ± 0.53
0.536IleMet: 0.536 ± 0.689
1.607IleAsn: 1.607 ± 0.539
2.142IlePro: 2.142 ± 0.989
3.749IleGln: 3.749 ± 0.731
1.607IleArg: 1.607 ± 0.978
5.356IleSer: 5.356 ± 1.719
2.142IleThr: 2.142 ± 2.635
4.821IleVal: 4.821 ± 1.005
0.536IleTrp: 0.536 ± 0.689
0.536IleTyr: 0.536 ± 0.326
0.0IleXaa: 0.0 ± 0.0
Lys
1.607LysAla: 1.607 ± 1.115
1.071LysCys: 1.071 ± 0.376
2.678LysAsp: 2.678 ± 0.859
9.106LysGlu: 9.106 ± 2.367
1.071LysPhe: 1.071 ± 0.652
3.214LysGly: 3.214 ± 0.992
0.0LysHis: 0.0 ± 0.0
3.214LysIle: 3.214 ± 1.042
4.285LysLys: 4.285 ± 1.593
1.071LysLeu: 1.071 ± 0.927
0.0LysMet: 0.0 ± 0.0
1.607LysAsn: 1.607 ± 0.539
2.142LysPro: 2.142 ± 0.752
3.749LysGln: 3.749 ± 1.312
3.214LysArg: 3.214 ± 1.078
3.749LysSer: 3.749 ± 1.698
0.536LysThr: 0.536 ± 0.326
2.678LysVal: 2.678 ± 0.859
0.0LysTrp: 0.0 ± 0.0
4.821LysTyr: 4.821 ± 0.597
0.0LysXaa: 0.0 ± 0.0
Leu
10.177LeuAla: 10.177 ± 3.278
3.214LeuCys: 3.214 ± 1.06
3.214LeuAsp: 3.214 ± 1.042
4.821LeuGlu: 4.821 ± 0.889
2.678LeuPhe: 2.678 ± 1.163
4.821LeuGly: 4.821 ± 0.991
0.0LeuHis: 0.0 ± 0.0
4.821LeuIle: 4.821 ± 1.885
3.214LeuLys: 3.214 ± 0.596
6.963LeuLeu: 6.963 ± 2.324
3.214LeuMet: 3.214 ± 0.854
2.142LeuAsn: 2.142 ± 0.752
2.142LeuPro: 2.142 ± 1.226
1.607LeuGln: 1.607 ± 0.53
4.285LeuArg: 4.285 ± 0.953
9.106LeuSer: 9.106 ± 1.39
4.821LeuThr: 4.821 ± 0.597
6.963LeuVal: 6.963 ± 1.308
1.071LeuTrp: 1.071 ± 0.652
3.214LeuTyr: 3.214 ± 1.039
0.0LeuXaa: 0.0 ± 0.0
Met
2.678MetAla: 2.678 ± 1.862
0.0MetCys: 0.0 ± 0.0
1.071MetAsp: 1.071 ± 0.376
0.536MetGlu: 0.536 ± 0.326
0.0MetPhe: 0.0 ± 0.0
2.678MetGly: 2.678 ± 0.608
0.0MetHis: 0.0 ± 0.0
1.071MetIle: 1.071 ± 0.376
0.536MetLys: 0.536 ± 0.326
0.536MetLeu: 0.536 ± 0.689
0.0MetMet: 0.0 ± 0.0
0.0MetAsn: 0.0 ± 0.0
1.071MetPro: 1.071 ± 1.226
0.536MetGln: 0.536 ± 0.689
0.536MetArg: 0.536 ± 0.326
1.607MetSer: 1.607 ± 0.53
1.607MetThr: 1.607 ± 0.53
2.142MetVal: 2.142 ± 0.752
0.0MetTrp: 0.0 ± 0.0
1.071MetTyr: 1.071 ± 0.376
0.0MetXaa: 0.0 ± 0.0
Asn
1.607AsnAla: 1.607 ± 0.699
1.607AsnCys: 1.607 ± 0.779
1.071AsnAsp: 1.071 ± 0.376
0.536AsnGlu: 0.536 ± 0.326
1.071AsnPhe: 1.071 ± 1.226
2.142AsnGly: 2.142 ± 0.473
0.0AsnHis: 0.0 ± 0.0
2.142AsnIle: 2.142 ± 0.797
1.071AsnLys: 1.071 ± 0.376
5.356AsnLeu: 5.356 ± 1.719
1.071AsnMet: 1.071 ± 0.376
0.536AsnAsn: 0.536 ± 0.326
0.0AsnPro: 0.0 ± 0.0
0.536AsnGln: 0.536 ± 0.689
1.071AsnArg: 1.071 ± 0.652
3.749AsnSer: 3.749 ± 1.14
1.071AsnThr: 1.071 ± 0.754
0.536AsnVal: 0.536 ± 0.689
0.536AsnTrp: 0.536 ± 1.342
0.0AsnTyr: 0.0 ± 0.0
0.0AsnXaa: 0.0 ± 0.0
Pro
4.821ProAla: 4.821 ± 1.005
1.071ProCys: 1.071 ± 0.376
4.285ProAsp: 4.285 ± 1.591
5.892ProGlu: 5.892 ± 1.309
0.536ProPhe: 0.536 ± 0.689
5.892ProGly: 5.892 ± 1.071
1.607ProHis: 1.607 ± 2.55
1.071ProIle: 1.071 ± 1.378
1.071ProLys: 1.071 ± 1.226
5.892ProLeu: 5.892 ± 1.902
0.0ProMet: 0.0 ± 0.0
0.0ProAsn: 0.0 ± 0.0
2.142ProPro: 2.142 ± 0.752
2.142ProGln: 2.142 ± 0.797
1.607ProArg: 1.607 ± 0.53
5.356ProSer: 5.356 ± 1.968
6.427ProThr: 6.427 ± 0.747
3.214ProVal: 3.214 ± 1.078
1.071ProTrp: 1.071 ± 1.378
0.0ProTyr: 0.0 ± 0.0
0.0ProXaa: 0.0 ± 0.0
Gln
4.821GlnAla: 4.821 ± 1.657
0.536GlnCys: 0.536 ± 0.326
0.0GlnAsp: 0.0 ± 0.0
1.607GlnGlu: 1.607 ± 1.191
0.0GlnPhe: 0.0 ± 0.0
3.749GlnGly: 3.749 ± 0.878
2.142GlnHis: 2.142 ± 0.795
1.607GlnIle: 1.607 ± 1.263
2.142GlnLys: 2.142 ± 1.431
2.678GlnLeu: 2.678 ± 1.094
0.536GlnMet: 0.536 ± 0.563
0.536GlnAsn: 0.536 ± 0.326
2.142GlnPro: 2.142 ± 0.473
1.607GlnGln: 1.607 ± 1.045
1.607GlnArg: 1.607 ± 0.978
3.214GlnSer: 3.214 ± 1.039
3.214GlnThr: 3.214 ± 1.028
3.214GlnVal: 3.214 ± 1.72
0.536GlnTrp: 0.536 ± 0.326
0.536GlnTyr: 0.536 ± 0.689
0.0GlnXaa: 0.0 ± 0.0
Arg
2.678ArgAla: 2.678 ± 0.859
0.536ArgCys: 0.536 ± 0.326
3.214ArgAsp: 3.214 ± 1.405
4.821ArgGlu: 4.821 ± 1.59
3.214ArgPhe: 3.214 ± 1.405
6.427ArgGly: 6.427 ± 2.476
1.071ArgHis: 1.071 ± 2.685
2.142ArgIle: 2.142 ± 0.903
4.285ArgLys: 4.285 ± 1.799
5.356ArgLeu: 5.356 ± 1.346
0.0ArgMet: 0.0 ± 0.0
1.607ArgAsn: 1.607 ± 0.699
2.142ArgPro: 2.142 ± 0.795
1.607ArgGln: 1.607 ± 1.369
1.607ArgArg: 1.607 ± 0.53
3.214ArgSer: 3.214 ± 1.06
2.678ArgThr: 2.678 ± 1.094
10.177ArgVal: 10.177 ± 1.002
2.142ArgTrp: 2.142 ± 0.795
1.607ArgTyr: 1.607 ± 1.263
0.0ArgXaa: 0.0 ± 0.0
Ser
5.892SerAla: 5.892 ± 1.62
1.607SerCys: 1.607 ± 0.53
3.214SerAsp: 3.214 ± 1.042
4.285SerGlu: 4.285 ± 2.07
0.0SerPhe: 0.0 ± 0.0
9.641SerGly: 9.641 ± 2.135
1.607SerHis: 1.607 ± 0.53
3.749SerIle: 3.749 ± 0.878
9.641SerLys: 9.641 ± 1.409
9.106SerLeu: 9.106 ± 1.677
1.607SerMet: 1.607 ± 0.53
4.821SerAsn: 4.821 ± 1.975
3.749SerPro: 3.749 ± 0.878
2.678SerGln: 2.678 ± 0.623
9.106SerArg: 9.106 ± 0.69
14.997SerSer: 14.997 ± 3.136
5.892SerThr: 5.892 ± 1.718
8.034SerVal: 8.034 ± 1.607
2.142SerTrp: 2.142 ± 0.989
2.678SerTyr: 2.678 ± 1.1
0.0SerXaa: 0.0 ± 0.0
Thr
6.427ThrAla: 6.427 ± 1.565
1.607ThrCys: 1.607 ± 1.115
1.607ThrAsp: 1.607 ± 0.539
2.678ThrGlu: 2.678 ± 1.057
0.536ThrPhe: 0.536 ± 1.342
4.821ThrGly: 4.821 ± 1.146
1.607ThrHis: 1.607 ± 2.55
1.071ThrIle: 1.071 ± 1.378
0.0ThrLys: 0.0 ± 0.0
4.285ThrLeu: 4.285 ± 1.036
0.0ThrMet: 0.0 ± 0.0
2.678ThrAsn: 2.678 ± 0.608
6.963ThrPro: 6.963 ± 1.709
2.142ThrGln: 2.142 ± 1.509
4.285ThrArg: 4.285 ± 4.489
6.427ThrSer: 6.427 ± 2.078
5.356ThrThr: 5.356 ± 2.103
4.285ThrVal: 4.285 ± 0.873
4.285ThrTrp: 4.285 ± 0.947
1.607ThrTyr: 1.607 ± 1.436
0.0ThrXaa: 0.0 ± 0.0
Val
7.499ValAla: 7.499 ± 0.716
2.678ValCys: 2.678 ± 2.413
1.071ValAsp: 1.071 ± 0.613
4.821ValGlu: 4.821 ± 1.237
1.071ValPhe: 1.071 ± 1.226
1.607ValGly: 1.607 ± 0.539
1.071ValHis: 1.071 ± 0.376
5.356ValIle: 5.356 ± 2.147
2.678ValLys: 2.678 ± 0.859
10.177ValLeu: 10.177 ± 1.002
0.0ValMet: 0.0 ± 0.0
0.536ValAsn: 0.536 ± 0.326
2.678ValPro: 2.678 ± 0.859
3.214ValGln: 3.214 ± 1.129
5.356ValArg: 5.356 ± 1.479
8.034ValSer: 8.034 ± 1.743
8.034ValThr: 8.034 ± 2.894
3.749ValVal: 3.749 ± 0.801
2.678ValTrp: 2.678 ± 1.094
2.142ValTyr: 2.142 ± 0.752
0.0ValXaa: 0.0 ± 0.0
Trp
2.142TrpAla: 2.142 ± 0.473
0.536TrpCys: 0.536 ± 0.326
1.607TrpAsp: 1.607 ± 0.53
2.142TrpGlu: 2.142 ± 0.473
0.0TrpPhe: 0.0 ± 0.0
1.607TrpGly: 1.607 ± 1.436
0.536TrpHis: 0.536 ± 1.342
2.142TrpIle: 2.142 ± 0.752
1.607TrpLys: 1.607 ± 0.53
1.607TrpLeu: 1.607 ± 0.539
0.536TrpMet: 0.536 ± 0.296
0.536TrpAsn: 0.536 ± 0.326
2.142TrpPro: 2.142 ± 0.795
1.071TrpGln: 1.071 ± 0.376
0.0TrpArg: 0.0 ± 0.0
4.285TrpSer: 4.285 ± 0.962
0.536TrpThr: 0.536 ± 1.342
0.536TrpVal: 0.536 ± 0.326
0.0TrpTrp: 0.0 ± 0.0
0.536TrpTyr: 0.536 ± 0.689
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.142TyrAla: 2.142 ± 1.297
0.536TyrCys: 0.536 ± 0.326
2.678TyrAsp: 2.678 ± 1.752
0.0TyrGlu: 0.0 ± 0.0
0.0TyrPhe: 0.0 ± 0.0
4.821TyrGly: 4.821 ± 1.198
0.536TyrHis: 0.536 ± 0.326
1.071TyrIle: 1.071 ± 0.376
1.071TyrLys: 1.071 ± 0.376
3.214TyrLeu: 3.214 ± 1.028
0.0TyrMet: 0.0 ± 0.0
0.0TyrAsn: 0.0 ± 0.0
0.536TyrPro: 0.536 ± 0.326
0.0TyrGln: 0.0 ± 0.0
2.678TyrArg: 2.678 ± 1.057
2.142TyrSer: 2.142 ± 0.473
1.071TyrThr: 1.071 ± 1.226
1.071TyrVal: 1.071 ± 1.226
0.0TyrTrp: 0.0 ± 0.0
0.0TyrTyr: 0.0 ± 0.0
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 4 proteins (1868 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski