Human papillomavirus type 144

Taxonomy: Viruses; Monodnaviria; Shotokuvirae; Cossaviricota; Papovaviricetes; Zurhausenvirales; Papillomaviridae; Firstpapillomavirinae; Gammapapillomavirus; Gammapapillomavirus 17

Average proteome isoelectric point is 6.13

Get precalculated fractions of proteins

Acidic
pI < 6.8
6.8-7.4
pI > 7.4
Basic
    
All



Virtual 2D-PAGE plot for 7 proteins (isoelectric point calculated using IPC2_protein)

Get csv file with sequences according to given criteria:
        -     Method 

     -  kDa    
                                                                                      

* You can choose from 21 different methods for calculating isoelectric point

Summary statistics related to proteome-wise predictions


    
Protein with the lowest isoelectric point:
>tr|I3P6Q1|I3P6Q1_9PAPI Major capsid protein L1 OS=Human papillomavirus type 144 OX=1070417 GN=L1 PE=3 SV=1
MM1 pKa = 7.7DD2 pKa = 4.49AVYY5 pKa = 9.81PRR7 pKa = 11.84RR8 pKa = 11.84IKK10 pKa = 10.46RR11 pKa = 11.84DD12 pKa = 3.52SVDD15 pKa = 3.65NLYY18 pKa = 10.02KK19 pKa = 10.42QCAITGNCPPDD30 pKa = 3.48VKK32 pKa = 11.12DD33 pKa = 3.47KK34 pKa = 11.92VEE36 pKa = 4.25GNTLADD42 pKa = 3.57KK43 pKa = 10.53LLKK46 pKa = 10.14IFSSILFFGGLGIGTGKK63 pKa = 8.8GTGGTLGYY71 pKa = 10.44RR72 pKa = 11.84PLTPSTPRR80 pKa = 11.84VLPEE84 pKa = 3.72GTIVRR89 pKa = 11.84PTPPIDD95 pKa = 4.46PIGPPDD101 pKa = 4.77IISIDD106 pKa = 4.16AIDD109 pKa = 4.15PAGSSIVPLQEE120 pKa = 4.86AGGLPDD126 pKa = 3.34SGVIEE131 pKa = 4.82EE132 pKa = 4.61IPLVEE137 pKa = 4.81LGQPSVVSTSDD148 pKa = 3.99PISDD152 pKa = 3.07ISLPEE157 pKa = 3.84STPTVVTTADD167 pKa = 3.51DD168 pKa = 3.58TAVAVLDD175 pKa = 4.07ISPAQPAPKK184 pKa = 9.5RR185 pKa = 11.84IVVEE189 pKa = 4.5GRR191 pKa = 11.84VKK193 pKa = 10.35PYY195 pKa = 10.53QLVHH199 pKa = 6.43ISSLAATAPEE209 pKa = 4.2GADD212 pKa = 2.69INVFVDD218 pKa = 2.77SHH220 pKa = 7.47FDD222 pKa = 3.28GDD224 pKa = 4.38VIGGQYY230 pKa = 10.64EE231 pKa = 4.55EE232 pKa = 5.36IPLEE236 pKa = 5.04DD237 pKa = 3.72ISSINPPKK245 pKa = 10.36TSTPQGTVPRR255 pKa = 11.84LTQRR259 pKa = 11.84ARR261 pKa = 11.84NFYY264 pKa = 9.67GRR266 pKa = 11.84RR267 pKa = 11.84VQQVPTTNVDD277 pKa = 3.92FLSRR281 pKa = 11.84PSRR284 pKa = 11.84LVQFEE289 pKa = 4.27NPAFDD294 pKa = 5.23ADD296 pKa = 5.14DD297 pKa = 3.26ITLQFEE303 pKa = 3.99QDD305 pKa = 3.65LEE307 pKa = 4.38QVLAAPDD314 pKa = 3.64TDD316 pKa = 3.84FQDD319 pKa = 3.08IRR321 pKa = 11.84KK322 pKa = 8.88LSSVSYY328 pKa = 10.71SDD330 pKa = 3.05VQGRR334 pKa = 11.84VRR336 pKa = 11.84VSRR339 pKa = 11.84LGTRR343 pKa = 11.84GTIQTRR349 pKa = 11.84SGVLIGEE356 pKa = 4.33DD357 pKa = 3.14VHH359 pKa = 8.34FYY361 pKa = 11.17FDD363 pKa = 5.52LSTIDD368 pKa = 3.27NSGAIEE374 pKa = 3.94LQPLGEE380 pKa = 4.22HH381 pKa = 6.2TGDD384 pKa = 3.25VTLVDD389 pKa = 4.53GLAEE393 pKa = 4.13SSFIDD398 pKa = 3.86AVDD401 pKa = 3.62NNEE404 pKa = 4.54LDD406 pKa = 5.01LEE408 pKa = 4.36TLLLDD413 pKa = 3.92EE414 pKa = 4.25QTEE417 pKa = 4.36DD418 pKa = 3.74FSNSHH423 pKa = 7.11LIITGTSRR431 pKa = 11.84QNTLSIPTIPPSVSLKK447 pKa = 10.61IFVDD451 pKa = 3.92DD452 pKa = 4.02VGDD455 pKa = 3.87NLFVSYY461 pKa = 9.78PKK463 pKa = 10.46SHH465 pKa = 6.56TPSDD469 pKa = 3.81TVFVDD474 pKa = 4.16TPFTPLDD481 pKa = 3.5PAILIDD487 pKa = 3.81VASDD491 pKa = 3.16TYY493 pKa = 11.06YY494 pKa = 10.31IHH496 pKa = 8.01PSLLKK501 pKa = 10.13KK502 pKa = 10.22GKK504 pKa = 8.97KK505 pKa = 9.3RR506 pKa = 11.84KK507 pKa = 9.96YY508 pKa = 10.52SDD510 pKa = 2.79IFF512 pKa = 4.01

Molecular weight: 55.3 kDa
Isoelectric point according different methods:





Protein with the highest isoelectric point:
>tr|I3P6P9|I3P6P9_9PAPI Uncharacterized protein OS=Human papillomavirus type 144 OX=1070417 GN=E4 PE=4 SV=1
MM1 pKa = 7.28ATLLRR6 pKa = 11.84DD7 pKa = 3.75RR8 pKa = 11.84FRR10 pKa = 11.84ALQEE14 pKa = 3.97ALMEE18 pKa = 4.6SYY20 pKa = 10.95EE21 pKa = 4.28SGATDD26 pKa = 3.47LHH28 pKa = 6.16SQLTYY33 pKa = 7.96WHH35 pKa = 7.16LVRR38 pKa = 11.84KK39 pKa = 8.09EE40 pKa = 3.61QAVLYY45 pKa = 10.05KK46 pKa = 10.51ARR48 pKa = 11.84QDD50 pKa = 3.62GLRR53 pKa = 11.84TLGLQPVPTLQVSEE67 pKa = 4.33YY68 pKa = 8.98RR69 pKa = 11.84AKK71 pKa = 10.55EE72 pKa = 4.27AISMTLLLRR81 pKa = 11.84TFIKK85 pKa = 10.61SQFARR90 pKa = 11.84EE91 pKa = 3.94SWTLQDD97 pKa = 3.59VSAEE101 pKa = 4.24LVLHH105 pKa = 6.47TKK107 pKa = 9.87PKK109 pKa = 9.1NTFKK113 pKa = 10.94KK114 pKa = 9.58RR115 pKa = 11.84GYY117 pKa = 7.4TVEE120 pKa = 3.99VLFDD124 pKa = 4.48HH125 pKa = 7.58DD126 pKa = 3.95PMKK129 pKa = 10.92AFPYY133 pKa = 10.22TNFTEE138 pKa = 5.46IYY140 pKa = 8.41YY141 pKa = 9.91QDD143 pKa = 4.24EE144 pKa = 4.13NEE146 pKa = 4.23MWHH149 pKa = 5.43KK150 pKa = 9.93TEE152 pKa = 4.99GKK154 pKa = 9.59VDD156 pKa = 3.8YY157 pKa = 11.09DD158 pKa = 3.27GMYY161 pKa = 10.56YY162 pKa = 10.25EE163 pKa = 5.13EE164 pKa = 4.89PNGDD168 pKa = 2.77RR169 pKa = 11.84VYY171 pKa = 11.03FQLFDD176 pKa = 4.4EE177 pKa = 5.1DD178 pKa = 3.82AQTYY182 pKa = 7.87GQSGQWTVNYY192 pKa = 10.35KK193 pKa = 8.71NTTLSPPVTSSTRR206 pKa = 11.84PTSSASTTGVGGTTDD221 pKa = 3.09TEE223 pKa = 4.35AQQKK227 pKa = 9.04VPSGGLQTAEE237 pKa = 4.28VASTSSPSRR246 pKa = 11.84RR247 pKa = 11.84RR248 pKa = 11.84RR249 pKa = 11.84RR250 pKa = 11.84EE251 pKa = 3.56QQRR254 pKa = 11.84EE255 pKa = 4.1SPVPSKK261 pKa = 10.45RR262 pKa = 11.84RR263 pKa = 11.84RR264 pKa = 11.84RR265 pKa = 11.84SGSTGQGTVPTPGEE279 pKa = 3.69VGGRR283 pKa = 11.84HH284 pKa = 4.19RR285 pKa = 11.84TVARR289 pKa = 11.84TGLSRR294 pKa = 11.84IRR296 pKa = 11.84RR297 pKa = 11.84LQEE300 pKa = 3.4EE301 pKa = 4.25ARR303 pKa = 11.84DD304 pKa = 3.74PPIAIIKK311 pKa = 10.28GPANPLKK318 pKa = 10.43CWRR321 pKa = 11.84NRR323 pKa = 11.84CNQKK327 pKa = 9.66YY328 pKa = 10.35ASFFVSMSTAWNWVNDD344 pKa = 3.84DD345 pKa = 3.34STKK348 pKa = 10.15QEE350 pKa = 3.75RR351 pKa = 11.84SRR353 pKa = 11.84LLVAFASTAQRR364 pKa = 11.84DD365 pKa = 4.0MFVKK369 pKa = 10.5LVNFPRR375 pKa = 11.84GTTYY379 pKa = 11.46AFGHH383 pKa = 6.93LDD385 pKa = 3.39SLL387 pKa = 4.57

Molecular weight: 44.1 kDa
Isoelectric point according different methods:





Peptides (in silico digests for buttom-up proteomics)

Below you can find in silico digests of the whole proteome with Trypsin, Chymotrypsin, Trypsin+LysC, LysN, ArgC proteases suitable for different mass spec machines.

Try
ESI
ChTry
ESI
ArgC
ESI
LysN
ESI
TryLysC
ESI

Try
MALDI
ChTry
MALDI
ArgC
MALDI
LysN
MALDI
TryLysC
MALDI

Try
LTQ
ChTry
LTQ
ArgC
LTQ
LysN
LTQ
TryLysC
LTQ

Try
MSlow
ChTry
MSlow
ArgC
MSlow
LysN
MSlow
TryLysC
MSlow

Try
MShigh
ChTry
MShigh
ArgC
MShigh
LysN
MShigh
TryLysC
MShigh

General Statistics

Number of major isoforms

Number of additional isoforms

Number of all proteins

Number of amino acids

Min. Seq. Length

Max. Seq. Length

Avg. Seq. Length

Avg. Mol. Weight

7

0

7

2404

99

599

343.4

38.9

Amino acid frequency

Ala

Cys

Asp

Glu

Phe

Gly

His

Ile

Lys

Leu

5.699 ± 0.314

1.913 ± 0.709

6.78 ± 0.686

6.24 ± 0.675

4.908 ± 0.475

5.366 ± 0.631

2.121 ± 0.238

5.491 ± 0.771

5.116 ± 0.576

9.235 ± 0.776

Met

Asn

Gln

Pro

Arg

Ser

Thr

Val

Trp

Tyr

1.83 ± 0.418

4.576 ± 0.909

6.115 ± 0.867

4.908 ± 0.376

6.198 ± 0.921

7.404 ± 0.725

6.073 ± 1.149

5.99 ± 0.7

1.206 ± 0.316

2.829 ± 0.437
Note: For amino acid frequency statistics the error has been estimated with the bootstraping (x100) at the protein level

Most of the basic statistics you can see at this page can be downloaded from this CSV file

For dipeptide frequency statistics click here
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski