Amino acid dipepetide frequency for Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	19.377AlaAla: 19.377 ± 0.162	1.038AlaCys: 1.038 ± 0.021	8.258AlaAsp: 8.258 ± 0.068	8.885AlaGlu: 8.885 ± 0.091	3.45AlaPhe: 3.45 ± 0.046	10.633AlaGly: 10.633 ± 0.079	2.385AlaHis: 2.385 ± 0.034	5.091AlaIle: 5.091 ± 0.053	3.716AlaLys: 3.716 ± 0.054	12.596AlaLeu: 12.596 ± 0.105	2.758AlaMet: 2.758 ± 0.041	2.49AlaAsn: 2.49 ± 0.033	5.415AlaPro: 5.415 ± 0.064	3.13AlaGln: 3.13 ± 0.04	8.325AlaArg: 8.325 ± 0.084	6.297AlaSer: 6.297 ± 0.06	7.629AlaThr: 7.629 ± 0.073	11.091AlaVal: 11.091 ± 0.083	1.799AlaTrp: 1.799 ± 0.032	2.345AlaTyr: 2.345 ± 0.031	0.0AlaXaa: 0.0 ± 0.0
Cys	0.953CysAla: 0.953 ± 0.023	0.101CysCys: 0.101 ± 0.008	0.604CysAsp: 0.604 ± 0.017	0.513CysGlu: 0.513 ± 0.015	0.231CysPhe: 0.231 ± 0.011	1.014CysGly: 1.014 ± 0.023	0.223CysHis: 0.223 ± 0.01	0.15CysIle: 0.15 ± 0.007	0.111CysLys: 0.111 ± 0.008	0.796CysLeu: 0.796 ± 0.02	0.118CysMet: 0.118 ± 0.008	0.128CysAsn: 0.128 ± 0.008	0.459CysPro: 0.459 ± 0.016	0.206CysGln: 0.206 ± 0.009	0.599CysArg: 0.599 ± 0.017	0.412CysSer: 0.412 ± 0.013	0.372CysThr: 0.372 ± 0.015	0.72CysVal: 0.72 ± 0.019	0.124CysTrp: 0.124 ± 0.008	0.179CysTyr: 0.179 ± 0.009	0.0CysXaa: 0.0 ± 0.0
Asp	7.972AspAla: 7.972 ± 0.068	0.496AspCys: 0.496 ± 0.016	4.74AspAsp: 4.74 ± 0.053	4.424AspGlu: 4.424 ± 0.047	1.918AspPhe: 1.918 ± 0.032	6.783AspGly: 6.783 ± 0.07	1.437AspHis: 1.437 ± 0.028	2.7AspIle: 2.7 ± 0.036	2.003AspLys: 2.003 ± 0.04	6.006AspLeu: 6.006 ± 0.066	1.101AspMet: 1.101 ± 0.022	1.668AspAsn: 1.668 ± 0.031	4.392AspPro: 4.392 ± 0.048	1.503AspGln: 1.503 ± 0.028	4.495AspArg: 4.495 ± 0.05	3.298AspSer: 3.298 ± 0.046	3.93AspThr: 3.93 ± 0.046	5.034AspVal: 5.034 ± 0.05	1.168AspTrp: 1.168 ± 0.026	1.453AspTyr: 1.453 ± 0.029	0.0AspXaa: 0.0 ± 0.0
Glu	7.173GluAla: 7.173 ± 0.073	0.44GluCys: 0.44 ± 0.015	2.877GluAsp: 2.877 ± 0.042	2.796GluGlu: 2.796 ± 0.049	1.858GluPhe: 1.858 ± 0.031	3.585GluGly: 3.585 ± 0.047	1.528GluHis: 1.528 ± 0.026	2.388GluIle: 2.388 ± 0.036	1.584GluLys: 1.584 ± 0.037	6.954GluLeu: 6.954 ± 0.072	0.923GluMet: 0.923 ± 0.02	1.153GluAsn: 1.153 ± 0.029	3.714GluPro: 3.714 ± 0.049	2.027GluGln: 2.027 ± 0.037	4.678GluArg: 4.678 ± 0.064	3.081GluSer: 3.081 ± 0.038	3.434GluThr: 3.434 ± 0.041	4.469GluVal: 4.469 ± 0.056	0.836GluTrp: 0.836 ± 0.02	1.409GluTyr: 1.409 ± 0.031	0.0GluXaa: 0.0 ± 0.0
Phe	4.144PheAla: 4.144 ± 0.051	0.257PheCys: 0.257 ± 0.013	2.489PheAsp: 2.489 ± 0.033	1.486PheGlu: 1.486 ± 0.026	0.883PhePhe: 0.883 ± 0.024	3.327PheGly: 3.327 ± 0.042	0.66PheHis: 0.66 ± 0.02	1.003PheIle: 1.003 ± 0.024	0.673PheLys: 0.673 ± 0.02	2.458PheLeu: 2.458 ± 0.039	0.448PheMet: 0.448 ± 0.016	0.712PheAsn: 0.712 ± 0.018	1.354PhePro: 1.354 ± 0.026	0.679PheGln: 0.679 ± 0.021	1.727PheArg: 1.727 ± 0.029	1.549PheSer: 1.549 ± 0.03	2.3PheThr: 2.3 ± 0.036	2.43PheVal: 2.43 ± 0.036	0.401PheTrp: 0.401 ± 0.016	0.673PheTyr: 0.673 ± 0.02	0.0PheXaa: 0.0 ± 0.0
Gly	9.023GlyAla: 9.023 ± 0.079	0.823GlyCys: 0.823 ± 0.021	5.797GlyAsp: 5.797 ± 0.061	5.171GlyGlu: 5.171 ± 0.059	3.197GlyPhe: 3.197 ± 0.041	7.751GlyGly: 7.751 ± 0.087	2.144GlyHis: 2.144 ± 0.031	3.816GlyIle: 3.816 ± 0.044	2.848GlyLys: 2.848 ± 0.045	8.933GlyLeu: 8.933 ± 0.083	2.077GlyMet: 2.077 ± 0.035	2.117GlyAsn: 2.117 ± 0.041	4.112GlyPro: 4.112 ± 0.051	2.698GlyGln: 2.698 ± 0.04	5.922GlyArg: 5.922 ± 0.055	4.938GlySer: 4.938 ± 0.046	5.307GlyThr: 5.307 ± 0.051	7.167GlyVal: 7.167 ± 0.072	1.677GlyTrp: 1.677 ± 0.033	2.42GlyTyr: 2.42 ± 0.042	0.0GlyXaa: 0.0 ± 0.0
His	2.366HisAla: 2.366 ± 0.038	0.222HisCys: 0.222 ± 0.011	1.525HisAsp: 1.525 ± 0.028	1.099HisGlu: 1.099 ± 0.026	0.652HisPhe: 0.652 ± 0.018	2.135HisGly: 2.135 ± 0.032	0.708HisHis: 0.708 ± 0.019	0.843HisIle: 0.843 ± 0.021	0.457HisLys: 0.457 ± 0.016	2.187HisLeu: 2.187 ± 0.036	0.37HisMet: 0.37 ± 0.013	0.515HisAsn: 0.515 ± 0.016	1.553HisPro: 1.553 ± 0.034	0.616HisGln: 0.616 ± 0.02	2.012HisArg: 2.012 ± 0.038	1.076HisSer: 1.076 ± 0.023	1.253HisThr: 1.253 ± 0.023	1.61HisVal: 1.61 ± 0.03	0.354HisTrp: 0.354 ± 0.012	0.506HisTyr: 0.506 ± 0.016	0.0HisXaa: 0.0 ± 0.0
Ile	6.146IleAla: 6.146 ± 0.057	0.31IleCys: 0.31 ± 0.013	3.102IleAsp: 3.102 ± 0.038	2.309IleGlu: 2.309 ± 0.037	0.949IlePhe: 0.949 ± 0.025	4.103IleGly: 4.103 ± 0.052	0.809IleHis: 0.809 ± 0.021	1.327IleIle: 1.327 ± 0.029	0.944IleLys: 0.944 ± 0.023	3.229IleLeu: 3.229 ± 0.047	0.659IleMet: 0.659 ± 0.016	0.926IleAsn: 0.926 ± 0.024	2.191IlePro: 2.191 ± 0.032	0.833IleGln: 0.833 ± 0.02	2.408IleArg: 2.408 ± 0.033	2.0IleSer: 2.0 ± 0.038	2.703IleThr: 2.703 ± 0.035	3.602IleVal: 3.602 ± 0.046	0.439IleTrp: 0.439 ± 0.014	0.703IleTyr: 0.703 ± 0.022	0.0IleXaa: 0.0 ± 0.0
Lys	3.186LysAla: 3.186 ± 0.052	0.162LysCys: 0.162 ± 0.01	1.615LysAsp: 1.615 ± 0.038	1.266LysGlu: 1.266 ± 0.03	0.655LysPhe: 0.655 ± 0.019	1.892LysGly: 1.892 ± 0.039	0.622LysHis: 0.622 ± 0.018	1.041LysIle: 1.041 ± 0.025	1.126LysLys: 1.126 ± 0.041	2.892LysLeu: 2.892 ± 0.045	0.454LysMet: 0.454 ± 0.016	0.618LysAsn: 0.618 ± 0.018	1.944LysPro: 1.944 ± 0.037	0.883LysGln: 0.883 ± 0.025	2.018LysArg: 2.018 ± 0.036	1.577LysSer: 1.577 ± 0.03	1.701LysThr: 1.701 ± 0.032	2.188LysVal: 2.188 ± 0.039	0.38LysTrp: 0.38 ± 0.013	0.584LysTyr: 0.584 ± 0.02	0.0LysXaa: 0.0 ± 0.0
Leu	14.548LeuAla: 14.548 ± 0.116	0.853LeuCys: 0.853 ± 0.025	6.77LeuAsp: 6.77 ± 0.066	4.482LeuGlu: 4.482 ± 0.057	2.647LeuPhe: 2.647 ± 0.043	8.828LeuGly: 8.828 ± 0.077	1.92LeuHis: 1.92 ± 0.033	3.911LeuIle: 3.911 ± 0.05	2.217LeuLys: 2.217 ± 0.042	10.46LeuLeu: 10.46 ± 0.114	1.629LeuMet: 1.629 ± 0.03	2.065LeuAsn: 2.065 ± 0.03	5.755LeuPro: 5.755 ± 0.061	1.64LeuGln: 1.64 ± 0.03	8.276LeuArg: 8.276 ± 0.071	6.368LeuSer: 6.368 ± 0.051	6.717LeuThr: 6.717 ± 0.066	8.295LeuVal: 8.295 ± 0.07	1.489LeuTrp: 1.489 ± 0.03	1.818LeuTyr: 1.818 ± 0.032	0.0LeuXaa: 0.0 ± 0.0
Met	2.303MetAla: 2.303 ± 0.034	0.135MetCys: 0.135 ± 0.009	1.116MetAsp: 1.116 ± 0.024	0.812MetGlu: 0.812 ± 0.024	0.647MetPhe: 0.647 ± 0.016	1.329MetGly: 1.329 ± 0.029	0.319MetHis: 0.319 ± 0.013	0.744MetIle: 0.744 ± 0.017	0.509MetLys: 0.509 ± 0.016	1.935MetLeu: 1.935 ± 0.033	0.374MetMet: 0.374 ± 0.013	0.596MetAsn: 0.596 ± 0.016	1.141MetPro: 1.141 ± 0.024	0.386MetGln: 0.386 ± 0.014	1.586MetArg: 1.586 ± 0.03	1.538MetSer: 1.538 ± 0.027	1.71MetThr: 1.71 ± 0.025	1.423MetVal: 1.423 ± 0.026	0.265MetTrp: 0.265 ± 0.012	0.398MetTyr: 0.398 ± 0.016	0.0MetXaa: 0.0 ± 0.0
Asn	2.488AsnAla: 2.488 ± 0.033	0.187AsnCys: 0.187 ± 0.009	1.382AsnAsp: 1.382 ± 0.034	1.054AsnGlu: 1.054 ± 0.023	0.611AsnPhe: 0.611 ± 0.018	2.167AsnGly: 2.167 ± 0.041	0.48AsnHis: 0.48 ± 0.015	0.864AsnIle: 0.864 ± 0.022	0.56AsnLys: 0.56 ± 0.018	2.197AsnLeu: 2.197 ± 0.033	0.379AsnMet: 0.379 ± 0.013	0.595AsnAsn: 0.595 ± 0.021	1.722AsnPro: 1.722 ± 0.032	0.623AsnGln: 0.623 ± 0.02	1.608AsnArg: 1.608 ± 0.03	1.139AsnSer: 1.139 ± 0.028	1.365AsnThr: 1.365 ± 0.03	1.636AsnVal: 1.636 ± 0.028	0.364AsnTrp: 0.364 ± 0.014	0.464AsnTyr: 0.464 ± 0.017	0.0AsnXaa: 0.0 ± 0.0
Pro	6.335ProAla: 6.335 ± 0.062	0.295ProCys: 0.295 ± 0.012	4.638ProAsp: 4.638 ± 0.053	3.989ProGlu: 3.989 ± 0.049	1.492ProPhe: 1.492 ± 0.027	5.634ProGly: 5.634 ± 0.064	1.232ProHis: 1.232 ± 0.03	1.898ProIle: 1.898 ± 0.031	1.607ProLys: 1.607 ± 0.031	4.736ProLeu: 4.736 ± 0.052	1.058ProMet: 1.058 ± 0.028	1.227ProAsn: 1.227 ± 0.026	3.442ProPro: 3.442 ± 0.084	1.738ProGln: 1.738 ± 0.034	3.608ProArg: 3.608 ± 0.049	3.246ProSer: 3.246 ± 0.041	3.187ProThr: 3.187 ± 0.035	4.824ProVal: 4.824 ± 0.058	0.878ProTrp: 0.878 ± 0.018	1.144ProTyr: 1.144 ± 0.025	0.0ProXaa: 0.0 ± 0.0
Gln	3.27GlnAla: 3.27 ± 0.047	0.175GlnCys: 0.175 ± 0.01	1.158GlnAsp: 1.158 ± 0.024	1.105GlnGlu: 1.105 ± 0.024	0.75GlnPhe: 0.75 ± 0.018	1.718GlnGly: 1.718 ± 0.033	0.631GlnHis: 0.631 ± 0.019	1.131GlnIle: 1.131 ± 0.021	0.595GlnLys: 0.595 ± 0.018	3.376GlnLeu: 3.376 ± 0.043	0.461GlnMet: 0.461 ± 0.016	0.505GlnAsn: 0.505 ± 0.016	1.822GlnPro: 1.822 ± 0.037	1.127GlnGln: 1.127 ± 0.034	2.525GlnArg: 2.525 ± 0.042	1.371GlnSer: 1.371 ± 0.025	1.405GlnThr: 1.405 ± 0.027	2.175GlnVal: 2.175 ± 0.034	0.536GlnTrp: 0.536 ± 0.017	0.596GlnTyr: 0.596 ± 0.017	0.0GlnXaa: 0.0 ± 0.0
Arg	7.879ArgAla: 7.879 ± 0.089	0.553ArgCys: 0.553 ± 0.015	4.736ArgAsp: 4.736 ± 0.046	4.41ArgGlu: 4.41 ± 0.049	2.549ArgPhe: 2.549 ± 0.042	5.087ArgGly: 5.087 ± 0.057	2.0ArgHis: 2.0 ± 0.032	3.176ArgIle: 3.176 ± 0.045	1.853ArgLys: 1.853 ± 0.029	8.504ArgLeu: 8.504 ± 0.09	1.702ArgMet: 1.702 ± 0.032	1.412ArgAsn: 1.412 ± 0.024	3.895ArgPro: 3.895 ± 0.043	2.487ArgGln: 2.487 ± 0.035	6.976ArgArg: 6.976 ± 0.077	3.527ArgSer: 3.527 ± 0.046	3.981ArgThr: 3.981 ± 0.043	5.646ArgVal: 5.646 ± 0.057	1.23ArgTrp: 1.23 ± 0.027	1.826ArgTyr: 1.826 ± 0.031	0.0ArgXaa: 0.0 ± 0.0
Ser	6.319SerAla: 6.319 ± 0.06	0.438SerCys: 0.438 ± 0.016	3.372SerAsp: 3.372 ± 0.049	2.838SerGlu: 2.838 ± 0.041	1.643SerPhe: 1.643 ± 0.033	6.13SerGly: 6.13 ± 0.07	1.162SerHis: 1.162 ± 0.023	2.12SerIle: 2.12 ± 0.027	1.457SerLys: 1.457 ± 0.032	5.176SerLeu: 5.176 ± 0.057	1.306SerMet: 1.306 ± 0.024	1.11SerAsn: 1.11 ± 0.024	3.225SerPro: 3.225 ± 0.041	1.598SerGln: 1.598 ± 0.026	3.897SerArg: 3.897 ± 0.053	3.015SerSer: 3.015 ± 0.051	3.386SerThr: 3.386 ± 0.039	4.239SerVal: 4.239 ± 0.048	0.96SerTrp: 0.96 ± 0.023	1.285SerTyr: 1.285 ± 0.024	0.0SerXaa: 0.0 ± 0.0
Thr	8.146ThrAla: 8.146 ± 0.062	0.444ThrCys: 0.444 ± 0.017	4.057ThrAsp: 4.057 ± 0.046	3.682ThrGlu: 3.682 ± 0.047	1.663ThrPhe: 1.663 ± 0.031	6.286ThrGly: 6.286 ± 0.061	1.189ThrHis: 1.189 ± 0.028	2.591ThrIle: 2.591 ± 0.04	1.559ThrLys: 1.559 ± 0.034	5.622ThrLeu: 5.622 ± 0.051	1.289ThrMet: 1.289 ± 0.025	1.184ThrAsn: 1.184 ± 0.026	3.716ThrPro: 3.716 ± 0.047	1.408ThrGln: 1.408 ± 0.028	3.768ThrArg: 3.768 ± 0.046	3.31ThrSer: 3.31 ± 0.037	4.016ThrThr: 4.016 ± 0.053	6.432ThrVal: 6.432 ± 0.062	0.947ThrTrp: 0.947 ± 0.021	1.298ThrTyr: 1.298 ± 0.03	0.0ThrXaa: 0.0 ± 0.0
Val	11.124ValAla: 11.124 ± 0.086	0.718ValCys: 0.718 ± 0.02	5.905ValAsp: 5.905 ± 0.05	4.693ValGlu: 4.693 ± 0.048	2.552ValPhe: 2.552 ± 0.036	6.42ValGly: 6.42 ± 0.06	1.769ValHis: 1.769 ± 0.031	3.525ValIle: 3.525 ± 0.044	2.105ValLys: 2.105 ± 0.035	8.324ValLeu: 8.324 ± 0.075	1.511ValMet: 1.511 ± 0.03	1.952ValAsn: 1.952 ± 0.032	4.365ValPro: 4.365 ± 0.05	1.546ValGln: 1.546 ± 0.03	5.565ValArg: 5.565 ± 0.055	4.834ValSer: 4.834 ± 0.049	5.896ValThr: 5.896 ± 0.049	7.477ValVal: 7.477 ± 0.069	1.132ValTrp: 1.132 ± 0.023	1.672ValTyr: 1.672 ± 0.029	0.0ValXaa: 0.0 ± 0.0
Trp	1.487TrpAla: 1.487 ± 0.029	0.167TrpCys: 0.167 ± 0.008	0.888TrpAsp: 0.888 ± 0.021	0.68TrpGlu: 0.68 ± 0.016	0.574TrpPhe: 0.574 ± 0.018	1.004TrpGly: 1.004 ± 0.025	0.425TrpHis: 0.425 ± 0.015	0.712TrpIle: 0.712 ± 0.02	0.439TrpLys: 0.439 ± 0.015	1.956TrpLeu: 1.956 ± 0.031	0.328TrpMet: 0.328 ± 0.012	0.458TrpAsn: 0.458 ± 0.019	0.799TrpPro: 0.799 ± 0.022	0.607TrpGln: 0.607 ± 0.018	1.5TrpArg: 1.5 ± 0.027	0.963TrpSer: 0.963 ± 0.025	1.041TrpThr: 1.041 ± 0.023	0.975TrpVal: 0.975 ± 0.025	0.412TrpTrp: 0.412 ± 0.016	0.348TrpTyr: 0.348 ± 0.012	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.472TyrAla: 2.472 ± 0.035	0.2TyrCys: 0.2 ± 0.01	1.493TyrAsp: 1.493 ± 0.029	1.214TyrGlu: 1.214 ± 0.023	0.735TyrPhe: 0.735 ± 0.02	2.11TyrGly: 2.11 ± 0.033	0.42TyrHis: 0.42 ± 0.014	0.66TyrIle: 0.66 ± 0.017	0.441TyrLys: 0.441 ± 0.016	2.35TyrLeu: 2.35 ± 0.033	0.319TyrMet: 0.319 ± 0.013	0.451TyrAsn: 0.451 ± 0.014	1.194TyrPro: 1.194 ± 0.025	0.695TyrGln: 0.695 ± 0.02	1.936TyrArg: 1.936 ± 0.032	1.139TyrSer: 1.139 ± 0.024	1.271TyrThr: 1.271 ± 0.025	1.651TyrVal: 1.651 ± 0.034	0.373TyrTrp: 0.373 ± 0.014	0.538TyrTyr: 0.538 ± 0.02	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 6379 proteins (2067818 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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