Amino acid dipepetide frequency for Shigella phage Sf6 (Shigella flexneri bacteriophage VI) (Bacteriophage SfVI)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
9.082AlaAla: 9.082 ± 1.34
0.673AlaCys: 0.673 ± 0.247
5.466AlaAsp: 5.466 ± 0.777
7.148AlaGlu: 7.148 ± 1.651
3.112AlaPhe: 3.112 ± 0.505
6.139AlaGly: 6.139 ± 1.011
1.43AlaHis: 1.43 ± 0.402
7.232AlaIle: 7.232 ± 0.724
5.719AlaLys: 5.719 ± 1.131
6.728AlaLeu: 6.728 ± 0.815
3.784AlaMet: 3.784 ± 0.586
4.121AlaAsn: 4.121 ± 0.601
2.102AlaPro: 2.102 ± 0.481
4.878AlaGln: 4.878 ± 1.017
4.878AlaArg: 4.878 ± 0.713
4.205AlaSer: 4.205 ± 0.51
6.139AlaThr: 6.139 ± 0.781
5.719AlaVal: 5.719 ± 0.876
1.261AlaTrp: 1.261 ± 0.277
2.775AlaTyr: 2.775 ± 0.455
0.0AlaXaa: 0.0 ± 0.0
Cys
0.925CysAla: 0.925 ± 0.33
0.168CysCys: 0.168 ± 0.127
0.757CysAsp: 0.757 ± 0.265
0.673CysGlu: 0.673 ± 0.271
0.42CysPhe: 0.42 ± 0.212
1.766CysGly: 1.766 ± 0.384
0.505CysHis: 0.505 ± 0.216
0.589CysIle: 0.589 ± 0.215
0.925CysLys: 0.925 ± 0.277
0.841CysLeu: 0.841 ± 0.244
0.42CysMet: 0.42 ± 0.19
0.925CysAsn: 0.925 ± 0.339
0.589CysPro: 0.589 ± 0.265
0.336CysGln: 0.336 ± 0.165
0.841CysArg: 0.841 ± 0.286
1.093CysSer: 1.093 ± 0.337
0.252CysThr: 0.252 ± 0.138
1.177CysVal: 1.177 ± 0.307
0.252CysTrp: 0.252 ± 0.131
0.336CysTyr: 0.336 ± 0.198
0.0CysXaa: 0.0 ± 0.0
Asp
5.046AspAla: 5.046 ± 0.536
0.589AspCys: 0.589 ± 0.222
3.448AspAsp: 3.448 ± 0.621
3.027AspGlu: 3.027 ± 0.604
1.934AspPhe: 1.934 ± 0.393
4.962AspGly: 4.962 ± 0.612
1.093AspHis: 1.093 ± 0.33
3.953AspIle: 3.953 ± 0.488
3.616AspLys: 3.616 ± 0.56
4.457AspLeu: 4.457 ± 0.733
1.093AspMet: 1.093 ± 0.271
2.018AspAsn: 2.018 ± 0.398
2.187AspPro: 2.187 ± 0.496
1.682AspGln: 1.682 ± 0.322
3.28AspArg: 3.28 ± 0.608
3.448AspSer: 3.448 ± 0.525
2.523AspThr: 2.523 ± 0.558
3.616AspVal: 3.616 ± 0.548
0.757AspTrp: 0.757 ± 0.223
2.355AspTyr: 2.355 ± 0.43
0.0AspXaa: 0.0 ± 0.0
Glu
7.148GluAla: 7.148 ± 1.487
1.177GluCys: 1.177 ± 0.351
2.439GluAsp: 2.439 ± 0.452
4.625GluGlu: 4.625 ± 1.272
1.682GluPhe: 1.682 ± 0.443
2.859GluGly: 2.859 ± 0.459
1.009GluHis: 1.009 ± 0.253
4.457GluIle: 4.457 ± 0.772
5.13GluLys: 5.13 ± 0.718
5.719GluLeu: 5.719 ± 0.805
1.85GluMet: 1.85 ± 0.42
2.187GluAsn: 2.187 ± 0.475
2.018GluPro: 2.018 ± 0.365
4.289GluGln: 4.289 ± 0.651
5.214GluArg: 5.214 ± 1.075
5.13GluSer: 5.13 ± 0.717
3.027GluThr: 3.027 ± 0.529
3.448GluVal: 3.448 ± 0.683
1.514GluTrp: 1.514 ± 0.386
2.439GluTyr: 2.439 ± 0.413
0.0GluXaa: 0.0 ± 0.0
Phe
2.439PheAla: 2.439 ± 0.416
0.589PheCys: 0.589 ± 0.216
2.775PheAsp: 2.775 ± 0.43
2.271PheGlu: 2.271 ± 0.474
1.093PhePhe: 1.093 ± 0.392
2.187PheGly: 2.187 ± 0.45
0.336PheHis: 0.336 ± 0.173
2.775PheIle: 2.775 ± 0.484
1.682PheLys: 1.682 ± 0.348
2.271PheLeu: 2.271 ± 0.454
1.009PheMet: 1.009 ± 0.308
1.261PheAsn: 1.261 ± 0.273
1.093PhePro: 1.093 ± 0.324
1.261PheGln: 1.261 ± 0.358
1.766PheArg: 1.766 ± 0.468
3.196PheSer: 3.196 ± 0.617
2.271PheThr: 2.271 ± 0.423
1.514PheVal: 1.514 ± 0.33
0.336PheTrp: 0.336 ± 0.165
0.925PheTyr: 0.925 ± 0.298
0.0PheXaa: 0.0 ± 0.0
Gly
6.307GlyAla: 6.307 ± 0.801
0.505GlyCys: 0.505 ± 0.206
4.541GlyAsp: 4.541 ± 0.741
3.784GlyGlu: 3.784 ± 0.485
2.943GlyPhe: 2.943 ± 0.406
4.878GlyGly: 4.878 ± 0.577
0.841GlyHis: 0.841 ± 0.252
4.121GlyIle: 4.121 ± 0.547
5.214GlyLys: 5.214 ± 0.493
4.878GlyLeu: 4.878 ± 0.566
2.102GlyMet: 2.102 ± 0.492
2.859GlyAsn: 2.859 ± 0.438
0.925GlyPro: 0.925 ± 0.22
3.364GlyGln: 3.364 ± 0.687
4.709GlyArg: 4.709 ± 0.643
3.953GlySer: 3.953 ± 0.489
3.448GlyThr: 3.448 ± 0.497
4.794GlyVal: 4.794 ± 0.951
1.43GlyTrp: 1.43 ± 0.439
2.943GlyTyr: 2.943 ± 0.504
0.0GlyXaa: 0.0 ± 0.0
His
1.177HisAla: 1.177 ± 0.302
0.505HisCys: 0.505 ± 0.225
0.925HisAsp: 0.925 ± 0.255
2.102HisGlu: 2.102 ± 0.505
0.673HisPhe: 0.673 ± 0.261
1.766HisGly: 1.766 ± 0.403
0.252HisHis: 0.252 ± 0.149
0.925HisIle: 0.925 ± 0.261
1.177HisLys: 1.177 ± 0.272
0.925HisLeu: 0.925 ± 0.332
0.252HisMet: 0.252 ± 0.127
0.42HisAsn: 0.42 ± 0.192
0.673HisPro: 0.673 ± 0.217
0.757HisGln: 0.757 ± 0.279
1.093HisArg: 1.093 ± 0.278
0.925HisSer: 0.925 ± 0.254
0.252HisThr: 0.252 ± 0.135
1.093HisVal: 1.093 ± 0.353
0.168HisTrp: 0.168 ± 0.103
0.757HisTyr: 0.757 ± 0.271
0.0HisXaa: 0.0 ± 0.0
Ile
5.803IleAla: 5.803 ± 0.685
1.177IleCys: 1.177 ± 0.332
4.625IleAsp: 4.625 ± 0.503
5.13IleGlu: 5.13 ± 0.932
1.261IlePhe: 1.261 ± 0.4
4.373IleGly: 4.373 ± 0.646
1.346IleHis: 1.346 ± 0.351
3.784IleIle: 3.784 ± 0.647
2.355IleLys: 2.355 ± 0.47
4.289IleLeu: 4.289 ± 0.635
0.925IleMet: 0.925 ± 0.281
2.355IleAsn: 2.355 ± 0.507
3.364IlePro: 3.364 ± 0.47
2.859IleGln: 2.859 ± 0.514
4.457IleArg: 4.457 ± 0.481
3.28IleSer: 3.28 ± 0.372
4.037IleThr: 4.037 ± 0.598
2.775IleVal: 2.775 ± 0.362
1.093IleTrp: 1.093 ± 0.331
1.766IleTyr: 1.766 ± 0.344
0.0IleXaa: 0.0 ± 0.0
Lys
7.569LysAla: 7.569 ± 1.133
0.841LysCys: 0.841 ± 0.269
2.439LysAsp: 2.439 ± 0.437
4.625LysGlu: 4.625 ± 0.745
1.766LysPhe: 1.766 ± 0.356
3.953LysGly: 3.953 ± 0.633
1.009LysHis: 1.009 ± 0.297
2.523LysIle: 2.523 ± 0.515
4.794LysLys: 4.794 ± 0.818
5.13LysLeu: 5.13 ± 0.636
1.934LysMet: 1.934 ± 0.418
2.691LysAsn: 2.691 ± 0.421
3.868LysPro: 3.868 ± 0.616
2.943LysGln: 2.943 ± 0.616
4.794LysArg: 4.794 ± 0.71
3.448LysSer: 3.448 ± 0.533
2.187LysThr: 2.187 ± 0.41
2.607LysVal: 2.607 ± 0.575
0.673LysTrp: 0.673 ± 0.238
2.607LysTyr: 2.607 ± 0.457
0.0LysXaa: 0.0 ± 0.0
Leu
8.578LeuAla: 8.578 ± 0.82
0.841LeuCys: 0.841 ± 0.288
4.037LeuAsp: 4.037 ± 0.52
5.214LeuGlu: 5.214 ± 0.67
2.607LeuPhe: 2.607 ± 0.437
3.112LeuGly: 3.112 ± 0.66
1.093LeuHis: 1.093 ± 0.266
3.868LeuIle: 3.868 ± 0.601
4.625LeuLys: 4.625 ± 0.699
6.391LeuLeu: 6.391 ± 0.786
2.102LeuMet: 2.102 ± 0.361
3.448LeuAsn: 3.448 ± 0.613
4.037LeuPro: 4.037 ± 0.426
3.28LeuGln: 3.28 ± 0.697
5.382LeuArg: 5.382 ± 0.704
5.719LeuSer: 5.719 ± 0.933
4.878LeuThr: 4.878 ± 0.586
4.541LeuVal: 4.541 ± 0.702
1.177LeuTrp: 1.177 ± 0.299
2.187LeuTyr: 2.187 ± 0.375
0.0LeuXaa: 0.0 ± 0.0
Met
3.112MetAla: 3.112 ± 0.511
0.505MetCys: 0.505 ± 0.22
1.093MetAsp: 1.093 ± 0.255
1.682MetGlu: 1.682 ± 0.375
1.009MetPhe: 1.009 ± 0.306
1.43MetGly: 1.43 ± 0.424
0.42MetHis: 0.42 ± 0.184
1.682MetIle: 1.682 ± 0.445
2.102MetLys: 2.102 ± 0.452
2.607MetLeu: 2.607 ± 0.454
0.757MetMet: 0.757 ± 0.248
1.093MetAsn: 1.093 ± 0.276
1.261MetPro: 1.261 ± 0.318
1.598MetGln: 1.598 ± 0.357
1.514MetArg: 1.514 ± 0.378
2.523MetSer: 2.523 ± 0.486
1.85MetThr: 1.85 ± 0.353
1.177MetVal: 1.177 ± 0.302
0.252MetTrp: 0.252 ± 0.169
0.841MetTyr: 0.841 ± 0.292
0.0MetXaa: 0.0 ± 0.0
Asn
4.121AsnAla: 4.121 ± 0.748
0.757AsnCys: 0.757 ± 0.289
1.514AsnAsp: 1.514 ± 0.339
3.28AsnGlu: 3.28 ± 0.477
0.841AsnPhe: 0.841 ± 0.281
4.373AsnGly: 4.373 ± 0.552
1.43AsnHis: 1.43 ± 0.384
2.859AsnIle: 2.859 ± 0.551
2.859AsnLys: 2.859 ± 0.521
3.027AsnLeu: 3.027 ± 0.569
0.589AsnMet: 0.589 ± 0.22
2.607AsnAsn: 2.607 ± 0.48
2.355AsnPro: 2.355 ± 0.493
2.691AsnGln: 2.691 ± 0.544
2.439AsnArg: 2.439 ± 0.518
2.523AsnSer: 2.523 ± 0.422
1.934AsnThr: 1.934 ± 0.515
2.355AsnVal: 2.355 ± 0.486
0.42AsnTrp: 0.42 ± 0.178
1.261AsnTyr: 1.261 ± 0.335
0.0AsnXaa: 0.0 ± 0.0
Pro
3.112ProAla: 3.112 ± 0.634
0.42ProCys: 0.42 ± 0.19
2.943ProAsp: 2.943 ± 0.437
3.7ProGlu: 3.7 ± 0.594
1.598ProPhe: 1.598 ± 0.379
2.102ProGly: 2.102 ± 0.44
0.589ProHis: 0.589 ± 0.228
2.355ProIle: 2.355 ± 0.502
2.439ProLys: 2.439 ± 0.504
2.355ProLeu: 2.355 ± 0.505
1.346ProMet: 1.346 ± 0.338
1.598ProAsn: 1.598 ± 0.375
1.43ProPro: 1.43 ± 0.379
2.018ProGln: 2.018 ± 0.48
1.598ProArg: 1.598 ± 0.369
3.28ProSer: 3.28 ± 0.612
2.355ProThr: 2.355 ± 0.414
3.364ProVal: 3.364 ± 0.505
0.42ProTrp: 0.42 ± 0.196
0.505ProTyr: 0.505 ± 0.197
0.0ProXaa: 0.0 ± 0.0
Gln
5.046GlnAla: 5.046 ± 0.85
0.42GlnCys: 0.42 ± 0.165
1.85GlnAsp: 1.85 ± 0.378
2.102GlnGlu: 2.102 ± 0.489
2.102GlnPhe: 2.102 ± 0.486
2.439GlnGly: 2.439 ± 0.452
0.757GlnHis: 0.757 ± 0.229
3.364GlnIle: 3.364 ± 0.439
3.196GlnLys: 3.196 ± 0.484
3.953GlnLeu: 3.953 ± 0.578
2.018GlnMet: 2.018 ± 0.352
2.355GlnAsn: 2.355 ± 0.559
2.271GlnPro: 2.271 ± 0.516
5.803GlnGln: 5.803 ± 1.26
3.364GlnArg: 3.364 ± 0.637
3.448GlnSer: 3.448 ± 0.691
2.271GlnThr: 2.271 ± 0.509
2.523GlnVal: 2.523 ± 0.416
1.009GlnTrp: 1.009 ± 0.305
1.346GlnTyr: 1.346 ± 0.431
0.0GlnXaa: 0.0 ± 0.0
Arg
4.794ArgAla: 4.794 ± 0.631
1.009ArgCys: 1.009 ± 0.334
2.691ArgAsp: 2.691 ± 0.52
4.878ArgGlu: 4.878 ± 1.078
1.85ArgPhe: 1.85 ± 0.316
4.625ArgGly: 4.625 ± 0.661
1.346ArgHis: 1.346 ± 0.333
3.953ArgIle: 3.953 ± 0.645
5.298ArgLys: 5.298 ± 0.807
4.205ArgLeu: 4.205 ± 0.586
2.102ArgMet: 2.102 ± 0.474
3.196ArgAsn: 3.196 ± 0.456
2.102ArgPro: 2.102 ± 0.478
3.28ArgGln: 3.28 ± 0.677
4.541ArgArg: 4.541 ± 0.821
3.7ArgSer: 3.7 ± 0.583
1.85ArgThr: 1.85 ± 0.353
3.448ArgVal: 3.448 ± 0.593
1.261ArgTrp: 1.261 ± 0.353
2.943ArgTyr: 2.943 ± 0.508
0.0ArgXaa: 0.0 ± 0.0
Ser
4.373SerAla: 4.373 ± 0.545
0.673SerCys: 0.673 ± 0.207
3.7SerAsp: 3.7 ± 0.429
4.541SerGlu: 4.541 ± 0.551
2.691SerPhe: 2.691 ± 0.593
5.803SerGly: 5.803 ± 0.779
0.841SerHis: 0.841 ± 0.408
3.364SerIle: 3.364 ± 0.531
2.607SerLys: 2.607 ± 0.516
6.139SerLeu: 6.139 ± 0.742
2.271SerMet: 2.271 ± 0.494
3.7SerAsn: 3.7 ± 0.63
3.196SerPro: 3.196 ± 0.502
3.196SerGln: 3.196 ± 0.529
3.7SerArg: 3.7 ± 0.635
4.205SerSer: 4.205 ± 0.7
2.943SerThr: 2.943 ± 0.45
5.382SerVal: 5.382 ± 0.827
1.177SerTrp: 1.177 ± 0.314
1.514SerTyr: 1.514 ± 0.335
0.0SerXaa: 0.0 ± 0.0
Thr
4.962ThrAla: 4.962 ± 0.649
1.009ThrCys: 1.009 ± 0.291
3.532ThrAsp: 3.532 ± 0.466
2.691ThrGlu: 2.691 ± 0.453
1.682ThrPhe: 1.682 ± 0.496
3.953ThrGly: 3.953 ± 0.64
0.252ThrHis: 0.252 ± 0.157
2.775ThrIle: 2.775 ± 0.506
2.943ThrLys: 2.943 ± 0.479
3.616ThrLeu: 3.616 ± 0.622
1.346ThrMet: 1.346 ± 0.289
1.598ThrAsn: 1.598 ± 0.402
2.775ThrPro: 2.775 ± 0.542
2.018ThrGln: 2.018 ± 0.481
2.859ThrArg: 2.859 ± 0.596
3.532ThrSer: 3.532 ± 0.457
2.775ThrThr: 2.775 ± 0.683
4.121ThrVal: 4.121 ± 0.676
0.673ThrTrp: 0.673 ± 0.237
1.514ThrTyr: 1.514 ± 0.346
0.0ThrXaa: 0.0 ± 0.0
Val
4.457ValAla: 4.457 ± 0.606
0.841ValCys: 0.841 ± 0.263
2.691ValAsp: 2.691 ± 0.496
3.784ValGlu: 3.784 ± 0.439
1.934ValPhe: 1.934 ± 0.358
5.046ValGly: 5.046 ± 0.63
1.093ValHis: 1.093 ± 0.304
3.7ValIle: 3.7 ± 0.543
3.448ValLys: 3.448 ± 0.473
4.205ValLeu: 4.205 ± 0.519
1.85ValMet: 1.85 ± 0.341
3.532ValAsn: 3.532 ± 0.529
1.934ValPro: 1.934 ± 0.416
2.439ValGln: 2.439 ± 0.509
3.112ValArg: 3.112 ± 0.378
5.214ValSer: 5.214 ± 0.899
3.868ValThr: 3.868 ± 0.788
3.616ValVal: 3.616 ± 0.557
0.841ValTrp: 0.841 ± 0.28
2.439ValTyr: 2.439 ± 0.629
0.0ValXaa: 0.0 ± 0.0
Trp
1.598TrpAla: 1.598 ± 0.38
0.505TrpCys: 0.505 ± 0.203
0.757TrpAsp: 0.757 ± 0.249
0.42TrpGlu: 0.42 ± 0.274
0.841TrpPhe: 0.841 ± 0.309
0.673TrpGly: 0.673 ± 0.264
0.673TrpHis: 0.673 ± 0.239
0.505TrpIle: 0.505 ± 0.191
1.009TrpLys: 1.009 ± 0.32
2.187TrpLeu: 2.187 ± 0.425
0.505TrpMet: 0.505 ± 0.205
0.505TrpAsn: 0.505 ± 0.299
0.252TrpPro: 0.252 ± 0.146
0.589TrpGln: 0.589 ± 0.235
0.925TrpArg: 0.925 ± 0.308
1.177TrpSer: 1.177 ± 0.303
0.589TrpThr: 0.589 ± 0.213
1.177TrpVal: 1.177 ± 0.318
0.42TrpTrp: 0.42 ± 0.174
0.336TrpTyr: 0.336 ± 0.209
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.943TyrAla: 2.943 ± 0.602
0.589TyrCys: 0.589 ± 0.205
2.859TyrAsp: 2.859 ± 0.485
1.682TyrGlu: 1.682 ± 0.356
1.009TyrPhe: 1.009 ± 0.31
2.102TyrGly: 2.102 ± 0.368
0.505TyrHis: 0.505 ± 0.219
2.271TyrIle: 2.271 ± 0.421
1.346TyrLys: 1.346 ± 0.3
3.196TyrLeu: 3.196 ± 0.513
0.168TyrMet: 0.168 ± 0.13
1.766TyrAsn: 1.766 ± 0.409
1.093TyrPro: 1.093 ± 0.261
2.355TyrGln: 2.355 ± 0.398
2.607TyrArg: 2.607 ± 0.527
2.018TyrSer: 2.018 ± 0.305
1.177TyrThr: 1.177 ± 0.279
1.598TyrVal: 1.598 ± 0.323
0.505TyrTrp: 0.505 ± 0.224
1.093TyrTyr: 1.093 ± 0.278
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 66 proteins (11892 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski