Amino acid dipepetide frequency for Wuchan romanomermis nematode virus 1

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
4.235AlaAla: 4.235 ± 0.0
3.025AlaCys: 3.025 ± 0.0
4.235AlaAsp: 4.235 ± 0.0
3.226AlaGlu: 3.226 ± 0.0
1.008AlaPhe: 1.008 ± 0.0
2.017AlaGly: 2.017 ± 0.0
1.613AlaHis: 1.613 ± 0.0
5.041AlaIle: 5.041 ± 0.0
3.025AlaLys: 3.025 ± 0.0
5.243AlaLeu: 5.243 ± 0.0
2.017AlaMet: 2.017 ± 0.0
3.025AlaAsn: 3.025 ± 0.0
1.815AlaPro: 1.815 ± 0.0
2.218AlaGln: 2.218 ± 0.0
2.823AlaArg: 2.823 ± 0.0
2.621AlaSer: 2.621 ± 0.0
5.243AlaThr: 5.243 ± 0.0
3.63AlaVal: 3.63 ± 0.0
0.605AlaTrp: 0.605 ± 0.0
1.613AlaTyr: 1.613 ± 0.0
0.0AlaXaa: 0.0 ± 0.0
Cys
2.218CysAla: 2.218 ± 0.0
1.008CysCys: 1.008 ± 0.0
1.815CysAsp: 1.815 ± 0.0
0.807CysGlu: 0.807 ± 0.0
1.21CysPhe: 1.21 ± 0.0
2.218CysGly: 2.218 ± 0.0
1.008CysHis: 1.008 ± 0.0
1.21CysIle: 1.21 ± 0.0
1.008CysLys: 1.008 ± 0.0
1.815CysLeu: 1.815 ± 0.0
0.403CysMet: 0.403 ± 0.0
1.815CysAsn: 1.815 ± 0.0
1.008CysPro: 1.008 ± 0.0
1.815CysGln: 1.815 ± 0.0
1.412CysArg: 1.412 ± 0.0
3.831CysSer: 3.831 ± 0.0
1.613CysThr: 1.613 ± 0.0
2.42CysVal: 2.42 ± 0.0
0.403CysTrp: 0.403 ± 0.0
1.613CysTyr: 1.613 ± 0.0
0.0CysXaa: 0.0 ± 0.0
Asp
3.831AspAla: 3.831 ± 0.0
2.017AspCys: 2.017 ± 0.0
5.041AspAsp: 5.041 ± 0.0
5.646AspGlu: 5.646 ± 0.0
2.823AspPhe: 2.823 ± 0.0
4.033AspGly: 4.033 ± 0.0
1.815AspHis: 1.815 ± 0.0
4.638AspIle: 4.638 ± 0.0
4.638AspLys: 4.638 ± 0.0
5.243AspLeu: 5.243 ± 0.0
2.823AspMet: 2.823 ± 0.0
3.025AspAsn: 3.025 ± 0.0
2.42AspPro: 2.42 ± 0.0
1.412AspGln: 1.412 ± 0.0
1.815AspArg: 1.815 ± 0.0
2.42AspSer: 2.42 ± 0.0
4.235AspThr: 4.235 ± 0.0
5.041AspVal: 5.041 ± 0.0
1.613AspTrp: 1.613 ± 0.0
1.815AspTyr: 1.815 ± 0.0
0.0AspXaa: 0.0 ± 0.0
Glu
2.823GluAla: 2.823 ± 0.0
1.008GluCys: 1.008 ± 0.0
3.025GluAsp: 3.025 ± 0.0
3.025GluGlu: 3.025 ± 0.0
3.226GluPhe: 3.226 ± 0.0
1.412GluGly: 1.412 ± 0.0
2.017GluHis: 2.017 ± 0.0
4.84GluIle: 4.84 ± 0.0
2.823GluLys: 2.823 ± 0.0
5.646GluLeu: 5.646 ± 0.0
3.428GluMet: 3.428 ± 0.0
3.831GluAsn: 3.831 ± 0.0
0.605GluPro: 0.605 ± 0.0
2.42GluGln: 2.42 ± 0.0
2.017GluArg: 2.017 ± 0.0
2.621GluSer: 2.621 ± 0.0
2.823GluThr: 2.823 ± 0.0
1.815GluVal: 1.815 ± 0.0
1.412GluTrp: 1.412 ± 0.0
1.412GluTyr: 1.412 ± 0.0
0.0GluXaa: 0.0 ± 0.0
Phe
2.218PheAla: 2.218 ± 0.0
0.202PheCys: 0.202 ± 0.0
1.412PheAsp: 1.412 ± 0.0
2.218PheGlu: 2.218 ± 0.0
0.0PhePhe: 0.0 ± 0.0
1.613PheGly: 1.613 ± 0.0
0.202PheHis: 0.202 ± 0.0
3.025PheIle: 3.025 ± 0.0
2.218PheLys: 2.218 ± 0.0
1.21PheLeu: 1.21 ± 0.0
1.008PheMet: 1.008 ± 0.0
1.815PheAsn: 1.815 ± 0.0
0.605PhePro: 0.605 ± 0.0
0.403PheGln: 0.403 ± 0.0
0.807PheArg: 0.807 ± 0.0
1.613PheSer: 1.613 ± 0.0
1.613PheThr: 1.613 ± 0.0
2.823PheVal: 2.823 ± 0.0
0.0PheTrp: 0.0 ± 0.0
0.807PheTyr: 0.807 ± 0.0
0.0PheXaa: 0.0 ± 0.0
Gly
2.823GlyAla: 2.823 ± 0.0
0.807GlyCys: 0.807 ± 0.0
5.243GlyAsp: 5.243 ± 0.0
2.218GlyGlu: 2.218 ± 0.0
1.21GlyPhe: 1.21 ± 0.0
2.621GlyGly: 2.621 ± 0.0
0.807GlyHis: 0.807 ± 0.0
1.815GlyIle: 1.815 ± 0.0
3.831GlyLys: 3.831 ± 0.0
4.033GlyLeu: 4.033 ± 0.0
2.823GlyMet: 2.823 ± 0.0
4.033GlyAsn: 4.033 ± 0.0
1.21GlyPro: 1.21 ± 0.0
2.017GlyGln: 2.017 ± 0.0
1.412GlyArg: 1.412 ± 0.0
1.613GlySer: 1.613 ± 0.0
2.621GlyThr: 2.621 ± 0.0
3.428GlyVal: 3.428 ± 0.0
1.412GlyTrp: 1.412 ± 0.0
2.017GlyTyr: 2.017 ± 0.0
0.0GlyXaa: 0.0 ± 0.0
His
1.412HisAla: 1.412 ± 0.0
1.21HisCys: 1.21 ± 0.0
1.815HisAsp: 1.815 ± 0.0
2.218HisGlu: 2.218 ± 0.0
0.605HisPhe: 0.605 ± 0.0
1.613HisGly: 1.613 ± 0.0
0.807HisHis: 0.807 ± 0.0
1.008HisIle: 1.008 ± 0.0
2.42HisLys: 2.42 ± 0.0
2.42HisLeu: 2.42 ± 0.0
1.008HisMet: 1.008 ± 0.0
2.621HisAsn: 2.621 ± 0.0
1.008HisPro: 1.008 ± 0.0
1.412HisGln: 1.412 ± 0.0
1.008HisArg: 1.008 ± 0.0
1.412HisSer: 1.412 ± 0.0
2.621HisThr: 2.621 ± 0.0
2.42HisVal: 2.42 ± 0.0
0.605HisTrp: 0.605 ± 0.0
1.21HisTyr: 1.21 ± 0.0
0.0HisXaa: 0.0 ± 0.0
Ile
5.041IleAla: 5.041 ± 0.0
2.017IleCys: 2.017 ± 0.0
4.84IleAsp: 4.84 ± 0.0
5.041IleGlu: 5.041 ± 0.0
1.613IlePhe: 1.613 ± 0.0
1.412IleGly: 1.412 ± 0.0
2.017IleHis: 2.017 ± 0.0
4.84IleIle: 4.84 ± 0.0
6.05IleLys: 6.05 ± 0.0
4.235IleLeu: 4.235 ± 0.0
2.218IleMet: 2.218 ± 0.0
4.436IleAsn: 4.436 ± 0.0
2.017IlePro: 2.017 ± 0.0
3.226IleGln: 3.226 ± 0.0
2.017IleArg: 2.017 ± 0.0
3.428IleSer: 3.428 ± 0.0
4.033IleThr: 4.033 ± 0.0
3.428IleVal: 3.428 ± 0.0
0.605IleTrp: 0.605 ± 0.0
1.21IleTyr: 1.21 ± 0.0
0.0IleXaa: 0.0 ± 0.0
Lys
2.218LysAla: 2.218 ± 0.0
1.412LysCys: 1.412 ± 0.0
2.017LysAsp: 2.017 ± 0.0
3.428LysGlu: 3.428 ± 0.0
2.218LysPhe: 2.218 ± 0.0
3.831LysGly: 3.831 ± 0.0
2.218LysHis: 2.218 ± 0.0
3.63LysIle: 3.63 ± 0.0
4.235LysLys: 4.235 ± 0.0
6.453LysLeu: 6.453 ± 0.0
2.218LysMet: 2.218 ± 0.0
3.025LysAsn: 3.025 ± 0.0
2.218LysPro: 2.218 ± 0.0
2.42LysGln: 2.42 ± 0.0
3.226LysArg: 3.226 ± 0.0
3.831LysSer: 3.831 ± 0.0
5.445LysThr: 5.445 ± 0.0
4.033LysVal: 4.033 ± 0.0
0.807LysTrp: 0.807 ± 0.0
2.017LysTyr: 2.017 ± 0.0
0.0LysXaa: 0.0 ± 0.0
Leu
4.235LeuAla: 4.235 ± 0.0
2.621LeuCys: 2.621 ± 0.0
4.033LeuAsp: 4.033 ± 0.0
3.025LeuGlu: 3.025 ± 0.0
1.815LeuPhe: 1.815 ± 0.0
5.848LeuGly: 5.848 ± 0.0
3.831LeuHis: 3.831 ± 0.0
4.638LeuIle: 4.638 ± 0.0
4.638LeuLys: 4.638 ± 0.0
6.251LeuLeu: 6.251 ± 0.0
3.226LeuMet: 3.226 ± 0.0
5.848LeuAsn: 5.848 ± 0.0
2.42LeuPro: 2.42 ± 0.0
4.84LeuGln: 4.84 ± 0.0
5.041LeuArg: 5.041 ± 0.0
5.848LeuSer: 5.848 ± 0.0
6.856LeuThr: 6.856 ± 0.0
6.453LeuVal: 6.453 ± 0.0
1.412LeuTrp: 1.412 ± 0.0
1.613LeuTyr: 1.613 ± 0.0
0.0LeuXaa: 0.0 ± 0.0
Met
3.025MetAla: 3.025 ± 0.0
0.403MetCys: 0.403 ± 0.0
2.621MetAsp: 2.621 ± 0.0
2.42MetGlu: 2.42 ± 0.0
0.807MetPhe: 0.807 ± 0.0
1.008MetGly: 1.008 ± 0.0
1.412MetHis: 1.412 ± 0.0
0.807MetIle: 0.807 ± 0.0
1.613MetLys: 1.613 ± 0.0
4.638MetLeu: 4.638 ± 0.0
1.412MetMet: 1.412 ± 0.0
2.218MetAsn: 2.218 ± 0.0
1.21MetPro: 1.21 ± 0.0
1.412MetGln: 1.412 ± 0.0
2.621MetArg: 2.621 ± 0.0
3.428MetSer: 3.428 ± 0.0
2.823MetThr: 2.823 ± 0.0
3.63MetVal: 3.63 ± 0.0
0.403MetTrp: 0.403 ± 0.0
1.008MetTyr: 1.008 ± 0.0
0.0MetXaa: 0.0 ± 0.0
Asn
3.63AsnAla: 3.63 ± 0.0
2.017AsnCys: 2.017 ± 0.0
3.63AsnAsp: 3.63 ± 0.0
3.63AsnGlu: 3.63 ± 0.0
2.017AsnPhe: 2.017 ± 0.0
3.226AsnGly: 3.226 ± 0.0
1.613AsnHis: 1.613 ± 0.0
4.033AsnIle: 4.033 ± 0.0
2.823AsnLys: 2.823 ± 0.0
6.655AsnLeu: 6.655 ± 0.0
1.412AsnMet: 1.412 ± 0.0
3.831AsnAsn: 3.831 ± 0.0
3.025AsnPro: 3.025 ± 0.0
2.218AsnGln: 2.218 ± 0.0
2.017AsnArg: 2.017 ± 0.0
3.226AsnSer: 3.226 ± 0.0
4.84AsnThr: 4.84 ± 0.0
5.848AsnVal: 5.848 ± 0.0
1.21AsnTrp: 1.21 ± 0.0
1.412AsnTyr: 1.412 ± 0.0
0.0AsnXaa: 0.0 ± 0.0
Pro
1.21ProAla: 1.21 ± 0.0
1.21ProCys: 1.21 ± 0.0
3.428ProAsp: 3.428 ± 0.0
2.621ProGlu: 2.621 ± 0.0
0.202ProPhe: 0.202 ± 0.0
1.21ProGly: 1.21 ± 0.0
1.008ProHis: 1.008 ± 0.0
1.412ProIle: 1.412 ± 0.0
2.017ProLys: 2.017 ± 0.0
3.025ProLeu: 3.025 ± 0.0
0.605ProMet: 0.605 ± 0.0
2.017ProAsn: 2.017 ± 0.0
1.21ProPro: 1.21 ± 0.0
2.017ProGln: 2.017 ± 0.0
2.621ProArg: 2.621 ± 0.0
3.226ProSer: 3.226 ± 0.0
2.823ProThr: 2.823 ± 0.0
2.218ProVal: 2.218 ± 0.0
0.807ProTrp: 0.807 ± 0.0
1.412ProTyr: 1.412 ± 0.0
0.0ProXaa: 0.0 ± 0.0
Gln
2.017GlnAla: 2.017 ± 0.0
1.613GlnCys: 1.613 ± 0.0
2.42GlnAsp: 2.42 ± 0.0
1.815GlnGlu: 1.815 ± 0.0
1.21GlnPhe: 1.21 ± 0.0
1.815GlnGly: 1.815 ± 0.0
1.815GlnHis: 1.815 ± 0.0
2.621GlnIle: 2.621 ± 0.0
1.21GlnLys: 1.21 ± 0.0
3.428GlnLeu: 3.428 ± 0.0
2.017GlnMet: 2.017 ± 0.0
2.218GlnAsn: 2.218 ± 0.0
3.831GlnPro: 3.831 ± 0.0
3.025GlnGln: 3.025 ± 0.0
2.621GlnArg: 2.621 ± 0.0
1.412GlnSer: 1.412 ± 0.0
3.226GlnThr: 3.226 ± 0.0
1.008GlnVal: 1.008 ± 0.0
1.412GlnTrp: 1.412 ± 0.0
0.807GlnTyr: 0.807 ± 0.0
0.0GlnXaa: 0.0 ± 0.0
Arg
2.823ArgAla: 2.823 ± 0.0
1.815ArgCys: 1.815 ± 0.0
2.823ArgAsp: 2.823 ± 0.0
2.017ArgGlu: 2.017 ± 0.0
1.008ArgPhe: 1.008 ± 0.0
2.218ArgGly: 2.218 ± 0.0
1.412ArgHis: 1.412 ± 0.0
2.823ArgIle: 2.823 ± 0.0
3.226ArgLys: 3.226 ± 0.0
6.453ArgLeu: 6.453 ± 0.0
1.412ArgMet: 1.412 ± 0.0
2.218ArgAsn: 2.218 ± 0.0
1.815ArgPro: 1.815 ± 0.0
1.21ArgGln: 1.21 ± 0.0
1.815ArgArg: 1.815 ± 0.0
3.831ArgSer: 3.831 ± 0.0
1.613ArgThr: 1.613 ± 0.0
3.226ArgVal: 3.226 ± 0.0
0.605ArgTrp: 0.605 ± 0.0
2.218ArgTyr: 2.218 ± 0.0
0.0ArgXaa: 0.0 ± 0.0
Ser
2.42SerAla: 2.42 ± 0.0
1.613SerCys: 1.613 ± 0.0
3.428SerAsp: 3.428 ± 0.0
1.21SerGlu: 1.21 ± 0.0
1.21SerPhe: 1.21 ± 0.0
3.226SerGly: 3.226 ± 0.0
2.017SerHis: 2.017 ± 0.0
3.831SerIle: 3.831 ± 0.0
3.831SerLys: 3.831 ± 0.0
5.041SerLeu: 5.041 ± 0.0
2.42SerMet: 2.42 ± 0.0
3.831SerAsn: 3.831 ± 0.0
2.621SerPro: 2.621 ± 0.0
2.017SerGln: 2.017 ± 0.0
2.42SerArg: 2.42 ± 0.0
4.638SerSer: 4.638 ± 0.0
6.251SerThr: 6.251 ± 0.0
4.033SerVal: 4.033 ± 0.0
0.605SerTrp: 0.605 ± 0.0
2.017SerTyr: 2.017 ± 0.0
0.0SerXaa: 0.0 ± 0.0
Thr
3.428ThrAla: 3.428 ± 0.0
3.226ThrCys: 3.226 ± 0.0
4.235ThrAsp: 4.235 ± 0.0
1.815ThrGlu: 1.815 ± 0.0
1.412ThrPhe: 1.412 ± 0.0
2.017ThrGly: 2.017 ± 0.0
2.218ThrHis: 2.218 ± 0.0
5.848ThrIle: 5.848 ± 0.0
4.84ThrLys: 4.84 ± 0.0
4.235ThrLeu: 4.235 ± 0.0
3.831ThrMet: 3.831 ± 0.0
4.033ThrAsn: 4.033 ± 0.0
3.025ThrPro: 3.025 ± 0.0
3.831ThrGln: 3.831 ± 0.0
2.823ThrArg: 2.823 ± 0.0
4.235ThrSer: 4.235 ± 0.0
9.276ThrThr: 9.276 ± 0.0
5.041ThrVal: 5.041 ± 0.0
1.21ThrTrp: 1.21 ± 0.0
3.63ThrTyr: 3.63 ± 0.0
0.0ThrXaa: 0.0 ± 0.0
Val
5.041ValAla: 5.041 ± 0.0
1.613ValCys: 1.613 ± 0.0
6.251ValAsp: 6.251 ± 0.0
4.235ValGlu: 4.235 ± 0.0
1.21ValPhe: 1.21 ± 0.0
4.235ValGly: 4.235 ± 0.0
1.008ValHis: 1.008 ± 0.0
4.436ValIle: 4.436 ± 0.0
4.436ValLys: 4.436 ± 0.0
5.041ValLeu: 5.041 ± 0.0
2.823ValMet: 2.823 ± 0.0
4.436ValAsn: 4.436 ± 0.0
2.823ValPro: 2.823 ± 0.0
2.017ValGln: 2.017 ± 0.0
5.445ValArg: 5.445 ± 0.0
3.428ValSer: 3.428 ± 0.0
4.033ValThr: 4.033 ± 0.0
7.26ValVal: 7.26 ± 0.0
1.008ValTrp: 1.008 ± 0.0
1.815ValTyr: 1.815 ± 0.0
0.0ValXaa: 0.0 ± 0.0
Trp
0.202TrpAla: 0.202 ± 0.0
0.605TrpCys: 0.605 ± 0.0
1.613TrpAsp: 1.613 ± 0.0
0.403TrpGlu: 0.403 ± 0.0
0.403TrpPhe: 0.403 ± 0.0
0.807TrpGly: 0.807 ± 0.0
1.21TrpHis: 1.21 ± 0.0
1.412TrpIle: 1.412 ± 0.0
0.403TrpLys: 0.403 ± 0.0
1.21TrpLeu: 1.21 ± 0.0
0.403TrpMet: 0.403 ± 0.0
1.008TrpAsn: 1.008 ± 0.0
0.807TrpPro: 0.807 ± 0.0
0.807TrpGln: 0.807 ± 0.0
1.21TrpArg: 1.21 ± 0.0
0.807TrpSer: 0.807 ± 0.0
0.605TrpThr: 0.605 ± 0.0
2.218TrpVal: 2.218 ± 0.0
0.605TrpTrp: 0.605 ± 0.0
0.202TrpTyr: 0.202 ± 0.0
0.0TrpXaa: 0.0 ± 0.0
Tyr
3.428TyrAla: 3.428 ± 0.0
1.21TyrCys: 1.21 ± 0.0
2.42TyrAsp: 2.42 ± 0.0
1.412TyrGlu: 1.412 ± 0.0
0.605TyrPhe: 0.605 ± 0.0
1.613TyrGly: 1.613 ± 0.0
0.807TyrHis: 0.807 ± 0.0
1.815TyrIle: 1.815 ± 0.0
1.613TyrLys: 1.613 ± 0.0
2.218TyrLeu: 2.218 ± 0.0
1.21TyrMet: 1.21 ± 0.0
3.025TyrAsn: 3.025 ± 0.0
0.605TyrPro: 0.605 ± 0.0
0.807TyrGln: 0.807 ± 0.0
1.412TyrArg: 1.412 ± 0.0
1.21TyrSer: 1.21 ± 0.0
1.613TyrThr: 1.613 ± 0.0
2.621TyrVal: 2.621 ± 0.0
0.202TyrTrp: 0.202 ± 0.0
0.807TyrTyr: 0.807 ± 0.0
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 1 proteins (4960 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski