Amino acid dipepetide frequency for Cohnella abietis

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	7.382AlaAla: 7.382 ± 0.081	0.644AlaCys: 0.644 ± 0.016	4.083AlaAsp: 4.083 ± 0.057	4.951AlaGlu: 4.951 ± 0.062	3.227AlaPhe: 3.227 ± 0.048	5.862AlaGly: 5.862 ± 0.064	1.354AlaHis: 1.354 ± 0.027	5.758AlaIle: 5.758 ± 0.059	4.171AlaLys: 4.171 ± 0.059	7.82AlaLeu: 7.82 ± 0.069	2.08AlaMet: 2.08 ± 0.038	3.032AlaAsn: 3.032 ± 0.042	2.553AlaPro: 2.553 ± 0.045	2.629AlaGln: 2.629 ± 0.04	3.171AlaArg: 3.171 ± 0.045	5.277AlaSer: 5.277 ± 0.059	4.358AlaThr: 4.358 ± 0.137	5.995AlaVal: 5.995 ± 0.072	0.941AlaTrp: 0.941 ± 0.027	2.505AlaTyr: 2.505 ± 0.041	0.0AlaXaa: 0.0 ± 0.0
Cys	0.454CysAla: 0.454 ± 0.017	0.099CysCys: 0.099 ± 0.007	0.415CysAsp: 0.415 ± 0.019	0.421CysGlu: 0.421 ± 0.013	0.298CysPhe: 0.298 ± 0.013	0.712CysGly: 0.712 ± 0.02	0.17CysHis: 0.17 ± 0.009	0.516CysIle: 0.516 ± 0.016	0.3CysLys: 0.3 ± 0.011	0.702CysLeu: 0.702 ± 0.02	0.185CysMet: 0.185 ± 0.009	0.276CysAsn: 0.276 ± 0.014	0.31CysPro: 0.31 ± 0.013	0.187CysGln: 0.187 ± 0.01	0.369CysArg: 0.369 ± 0.016	0.564CysSer: 0.564 ± 0.018	0.379CysThr: 0.379 ± 0.016	0.427CysVal: 0.427 ± 0.015	0.101CysTrp: 0.101 ± 0.008	0.278CysTyr: 0.278 ± 0.012	0.0CysXaa: 0.0 ± 0.0
Asp	3.656AspAla: 3.656 ± 0.052	0.352AspCys: 0.352 ± 0.013	2.535AspAsp: 2.535 ± 0.036	3.65AspGlu: 3.65 ± 0.047	2.191AspPhe: 2.191 ± 0.033	4.019AspGly: 4.019 ± 0.068	1.033AspHis: 1.033 ± 0.024	3.799AspIle: 3.799 ± 0.048	3.049AspLys: 3.049 ± 0.042	4.911AspLeu: 4.911 ± 0.052	1.256AspMet: 1.256 ± 0.022	2.272AspAsn: 2.272 ± 0.043	2.228AspPro: 2.228 ± 0.031	1.887AspGln: 1.887 ± 0.033	2.596AspArg: 2.596 ± 0.041	3.293AspSer: 3.293 ± 0.052	2.594AspThr: 2.594 ± 0.037	3.573AspVal: 3.573 ± 0.048	0.881AspTrp: 0.881 ± 0.028	2.125AspTyr: 2.125 ± 0.035	0.0AspXaa: 0.0 ± 0.0
Glu	5.521GluAla: 5.521 ± 0.065	0.361GluCys: 0.361 ± 0.013	2.999GluAsp: 2.999 ± 0.04	4.809GluGlu: 4.809 ± 0.066	2.191GluPhe: 2.191 ± 0.036	4.293GluGly: 4.293 ± 0.056	1.4GluHis: 1.4 ± 0.027	4.493GluIle: 4.493 ± 0.055	3.952GluLys: 3.952 ± 0.051	6.903GluLeu: 6.903 ± 0.071	1.916GluMet: 1.916 ± 0.03	2.569GluAsn: 2.569 ± 0.043	2.114GluPro: 2.114 ± 0.032	3.336GluGln: 3.336 ± 0.047	3.537GluArg: 3.537 ± 0.051	3.702GluSer: 3.702 ± 0.049	3.224GluThr: 3.224 ± 0.047	4.265GluVal: 4.265 ± 0.05	1.007GluTrp: 1.007 ± 0.025	2.038GluTyr: 2.038 ± 0.029	0.0GluXaa: 0.0 ± 0.0
Phe	3.096PheAla: 3.096 ± 0.042	0.354PheCys: 0.354 ± 0.016	2.37PheAsp: 2.37 ± 0.031	2.458PheGlu: 2.458 ± 0.038	1.827PhePhe: 1.827 ± 0.042	3.194PheGly: 3.194 ± 0.049	0.855PheHis: 0.855 ± 0.024	3.014PheIle: 3.014 ± 0.051	2.107PheLys: 2.107 ± 0.036	3.912PheLeu: 3.912 ± 0.057	1.052PheMet: 1.052 ± 0.022	1.892PheAsn: 1.892 ± 0.034	1.647PhePro: 1.647 ± 0.03	1.435PheGln: 1.435 ± 0.028	1.987PheArg: 1.987 ± 0.033	3.03PheSer: 3.03 ± 0.04	2.547PheThr: 2.547 ± 0.042	2.984PheVal: 2.984 ± 0.043	0.525PheTrp: 0.525 ± 0.017	1.555PheTyr: 1.555 ± 0.032	0.0PheXaa: 0.0 ± 0.0
Gly	5.366GlyAla: 5.366 ± 0.132	0.638GlyCys: 0.638 ± 0.017	3.502GlyAsp: 3.502 ± 0.051	4.212GlyGlu: 4.212 ± 0.06	3.259GlyPhe: 3.259 ± 0.043	5.338GlyGly: 5.338 ± 0.075	1.426GlyHis: 1.426 ± 0.025	5.631GlyIle: 5.631 ± 0.059	4.631GlyLys: 4.631 ± 0.051	7.047GlyLeu: 7.047 ± 0.074	2.181GlyMet: 2.181 ± 0.038	3.1GlyAsn: 3.1 ± 0.054	1.788GlyPro: 1.788 ± 0.035	2.541GlyGln: 2.541 ± 0.038	3.076GlyArg: 3.076 ± 0.046	4.872GlySer: 4.872 ± 0.072	4.53GlyThr: 4.53 ± 0.071	5.166GlyVal: 5.166 ± 0.077	1.167GlyTrp: 1.167 ± 0.025	2.941GlyTyr: 2.941 ± 0.044	0.0GlyXaa: 0.0 ± 0.0
His	1.387HisAla: 1.387 ± 0.029	0.163HisCys: 0.163 ± 0.009	0.96HisAsp: 0.96 ± 0.023	1.215HisGlu: 1.215 ± 0.026	1.012HisPhe: 1.012 ± 0.026	1.363HisGly: 1.363 ± 0.027	0.569HisHis: 0.569 ± 0.017	1.325HisIle: 1.325 ± 0.031	0.908HisLys: 0.908 ± 0.025	2.002HisLeu: 2.002 ± 0.039	0.487HisMet: 0.487 ± 0.013	0.777HisAsn: 0.777 ± 0.018	1.156HisPro: 1.156 ± 0.026	0.691HisGln: 0.691 ± 0.019	0.955HisArg: 0.955 ± 0.021	1.304HisSer: 1.304 ± 0.029	1.036HisThr: 1.036 ± 0.021	1.285HisVal: 1.285 ± 0.027	0.341HisTrp: 0.341 ± 0.013	0.863HisTyr: 0.863 ± 0.021	0.0HisXaa: 0.0 ± 0.0
Ile	6.0IleAla: 6.0 ± 0.05	0.601IleCys: 0.601 ± 0.018	3.998IleAsp: 3.998 ± 0.047	4.46IleGlu: 4.46 ± 0.052	2.556IlePhe: 2.556 ± 0.047	5.421IleGly: 5.421 ± 0.055	1.465IleHis: 1.465 ± 0.031	4.78IleIle: 4.78 ± 0.07	3.615IleLys: 3.615 ± 0.048	5.945IleLeu: 5.945 ± 0.072	1.659IleMet: 1.659 ± 0.029	3.011IleAsn: 3.011 ± 0.044	3.331IlePro: 3.331 ± 0.041	2.612IleGln: 2.612 ± 0.038	3.71IleArg: 3.71 ± 0.048	5.051IleSer: 5.051 ± 0.058	4.202IleThr: 4.202 ± 0.06	5.766IleVal: 5.766 ± 0.067	0.772IleTrp: 0.772 ± 0.023	2.248IleTyr: 2.248 ± 0.038	0.0IleXaa: 0.0 ± 0.0
Lys	4.487LysAla: 4.487 ± 0.049	0.259LysCys: 0.259 ± 0.012	3.101LysAsp: 3.101 ± 0.046	4.231LysGlu: 4.231 ± 0.059	1.771LysPhe: 1.771 ± 0.033	3.783LysGly: 3.783 ± 0.045	1.059LysHis: 1.059 ± 0.024	3.553LysIle: 3.553 ± 0.051	3.467LysLys: 3.467 ± 0.054	5.926LysLeu: 5.926 ± 0.07	1.625LysMet: 1.625 ± 0.028	2.316LysAsn: 2.316 ± 0.043	2.34LysPro: 2.34 ± 0.035	2.597LysGln: 2.597 ± 0.042	2.655LysArg: 2.655 ± 0.038	3.459LysSer: 3.459 ± 0.042	2.831LysThr: 2.831 ± 0.047	3.871LysVal: 3.871 ± 0.046	0.815LysTrp: 0.815 ± 0.022	1.924LysTyr: 1.924 ± 0.037	0.0LysXaa: 0.0 ± 0.0
Leu	7.668LeuAla: 7.668 ± 0.067	0.783LeuCys: 0.783 ± 0.021	5.081LeuAsp: 5.081 ± 0.057	6.203LeuGlu: 6.203 ± 0.072	4.51LeuPhe: 4.51 ± 0.059	6.396LeuGly: 6.396 ± 0.071	1.979LeuHis: 1.979 ± 0.034	6.893LeuIle: 6.893 ± 0.073	5.58LeuLys: 5.58 ± 0.056	10.802LeuLeu: 10.802 ± 0.116	2.479LeuMet: 2.479 ± 0.035	4.302LeuAsn: 4.302 ± 0.052	4.332LeuPro: 4.332 ± 0.046	3.99LeuGln: 3.99 ± 0.053	4.625LeuArg: 4.625 ± 0.054	7.427LeuSer: 7.427 ± 0.058	5.858LeuThr: 5.858 ± 0.063	6.458LeuVal: 6.458 ± 0.073	1.1LeuTrp: 1.1 ± 0.025	3.172LeuTyr: 3.172 ± 0.04	0.0LeuXaa: 0.0 ± 0.0
Met	1.961MetAla: 1.961 ± 0.031	0.151MetCys: 0.151 ± 0.009	1.422MetAsp: 1.422 ± 0.026	1.698MetGlu: 1.698 ± 0.031	1.013MetPhe: 1.013 ± 0.023	1.707MetGly: 1.707 ± 0.034	0.454MetHis: 0.454 ± 0.014	1.841MetIle: 1.841 ± 0.031	1.918MetLys: 1.918 ± 0.029	2.76MetLeu: 2.76 ± 0.033	0.769MetMet: 0.769 ± 0.022	1.457MetAsn: 1.457 ± 0.03	1.039MetPro: 1.039 ± 0.024	0.941MetGln: 0.941 ± 0.021	1.268MetArg: 1.268 ± 0.023	1.838MetSer: 1.838 ± 0.033	1.614MetThr: 1.614 ± 0.03	1.599MetVal: 1.599 ± 0.029	0.231MetTrp: 0.231 ± 0.011	0.73MetTyr: 0.73 ± 0.02	0.0MetXaa: 0.0 ± 0.0
Asn	3.226AsnAla: 3.226 ± 0.045	0.287AsnCys: 0.287 ± 0.012	2.223AsnAsp: 2.223 ± 0.037	2.879AsnGlu: 2.879 ± 0.039	1.455AsnPhe: 1.455 ± 0.029	3.764AsnGly: 3.764 ± 0.062	0.92AsnHis: 0.92 ± 0.02	2.832AsnIle: 2.832 ± 0.04	2.606AsnLys: 2.606 ± 0.044	3.596AsnLeu: 3.596 ± 0.047	1.052AsnMet: 1.052 ± 0.023	2.172AsnAsn: 2.172 ± 0.049	2.207AsnPro: 2.207 ± 0.039	1.666AsnGln: 1.666 ± 0.03	2.25AsnArg: 2.25 ± 0.036	2.728AsnSer: 2.728 ± 0.044	2.258AsnThr: 2.258 ± 0.041	3.0AsnVal: 3.0 ± 0.043	0.622AsnTrp: 0.622 ± 0.018	1.571AsnTyr: 1.571 ± 0.027	0.0AsnXaa: 0.0 ± 0.0
Pro	2.944ProAla: 2.944 ± 0.047	0.231ProCys: 0.231 ± 0.01	2.475ProAsp: 2.475 ± 0.037	3.069ProGlu: 3.069 ± 0.039	1.821ProPhe: 1.821 ± 0.031	2.622ProGly: 2.622 ± 0.034	0.833ProHis: 0.833 ± 0.021	2.863ProIle: 2.863 ± 0.044	1.863ProLys: 1.863 ± 0.036	3.843ProLeu: 3.843 ± 0.049	0.896ProMet: 0.896 ± 0.019	1.778ProAsn: 1.778 ± 0.034	1.235ProPro: 1.235 ± 0.027	1.341ProGln: 1.341 ± 0.027	1.309ProArg: 1.309 ± 0.029	2.833ProSer: 2.833 ± 0.044	2.39ProThr: 2.39 ± 0.048	2.961ProVal: 2.961 ± 0.042	0.519ProTrp: 0.519 ± 0.015	1.521ProTyr: 1.521 ± 0.032	0.0ProXaa: 0.0 ± 0.0
Gln	3.243GlnAla: 3.243 ± 0.043	0.204GlnCys: 0.204 ± 0.011	1.631GlnAsp: 1.631 ± 0.028	2.401GlnGlu: 2.401 ± 0.038	1.621GlnPhe: 1.621 ± 0.029	2.447GlnGly: 2.447 ± 0.035	0.723GlnHis: 0.723 ± 0.022	2.675GlnIle: 2.675 ± 0.04	1.887GlnLys: 1.887 ± 0.032	4.338GlnLeu: 4.338 ± 0.054	1.087GlnMet: 1.087 ± 0.022	1.302GlnAsn: 1.302 ± 0.025	1.407GlnPro: 1.407 ± 0.027	1.812GlnGln: 1.812 ± 0.033	1.737GlnArg: 1.737 ± 0.032	2.443GlnSer: 2.443 ± 0.035	1.994GlnThr: 1.994 ± 0.031	2.466GlnVal: 2.466 ± 0.033	0.607GlnTrp: 0.607 ± 0.017	1.37GlnTyr: 1.37 ± 0.028	0.0GlnXaa: 0.0 ± 0.0
Arg	3.108ArgAla: 3.108 ± 0.044	0.314ArgCys: 0.314 ± 0.013	2.3ArgAsp: 2.3 ± 0.036	3.35ArgGlu: 3.35 ± 0.045	2.165ArgPhe: 2.165 ± 0.034	2.748ArgGly: 2.748 ± 0.041	0.917ArgHis: 0.917 ± 0.021	3.564ArgIle: 3.564 ± 0.04	2.977ArgLys: 2.977 ± 0.05	4.99ArgLeu: 4.99 ± 0.058	1.52ArgMet: 1.52 ± 0.029	2.127ArgAsn: 2.127 ± 0.033	1.517ArgPro: 1.517 ± 0.031	1.767ArgGln: 1.767 ± 0.034	2.464ArgArg: 2.464 ± 0.043	3.035ArgSer: 3.035 ± 0.051	2.508ArgThr: 2.508 ± 0.038	2.985ArgVal: 2.985 ± 0.048	0.636ArgTrp: 0.636 ± 0.018	1.764ArgTyr: 1.764 ± 0.032	0.0ArgXaa: 0.0 ± 0.0
Ser	4.851SerAla: 4.851 ± 0.058	0.434SerCys: 0.434 ± 0.017	3.528SerAsp: 3.528 ± 0.056	4.027SerGlu: 4.027 ± 0.05	3.204SerPhe: 3.204 ± 0.042	5.561SerGly: 5.561 ± 0.061	1.287SerHis: 1.287 ± 0.028	5.016SerIle: 5.016 ± 0.054	3.721SerLys: 3.721 ± 0.052	6.739SerLeu: 6.739 ± 0.066	1.783SerMet: 1.783 ± 0.032	3.023SerAsn: 3.023 ± 0.047	2.667SerPro: 2.667 ± 0.039	2.185SerGln: 2.185 ± 0.03	3.013SerArg: 3.013 ± 0.037	5.186SerSer: 5.186 ± 0.062	3.626SerThr: 3.626 ± 0.044	4.849SerVal: 4.849 ± 0.081	0.941SerTrp: 0.941 ± 0.025	2.562SerTyr: 2.562 ± 0.037	0.0SerXaa: 0.0 ± 0.0
Thr	4.642ThrAla: 4.642 ± 0.066	0.309ThrCys: 0.309 ± 0.013	2.965ThrAsp: 2.965 ± 0.041	3.303ThrGlu: 3.303 ± 0.045	2.497ThrPhe: 2.497 ± 0.038	4.755ThrGly: 4.755 ± 0.215	1.029ThrHis: 1.029 ± 0.025	4.361ThrIle: 4.361 ± 0.057	2.775ThrLys: 2.775 ± 0.041	5.672ThrLeu: 5.672 ± 0.051	1.283ThrMet: 1.283 ± 0.025	2.326ThrAsn: 2.326 ± 0.041	2.699ThrPro: 2.699 ± 0.056	1.69ThrGln: 1.69 ± 0.027	2.239ThrArg: 2.239 ± 0.037	3.719ThrSer: 3.719 ± 0.06	3.163ThrThr: 3.163 ± 0.05	4.631ThrVal: 4.631 ± 0.088	0.684ThrTrp: 0.684 ± 0.02	1.933ThrTyr: 1.933 ± 0.036	0.0ThrXaa: 0.0 ± 0.0
Val	5.382ValAla: 5.382 ± 0.064	0.573ValCys: 0.573 ± 0.017	3.649ValAsp: 3.649 ± 0.047	4.209ValGlu: 4.209 ± 0.05	2.984ValPhe: 2.984 ± 0.043	4.836ValGly: 4.836 ± 0.052	1.321ValHis: 1.321 ± 0.031	5.115ValIle: 5.115 ± 0.051	4.006ValLys: 4.006 ± 0.056	6.846ValLeu: 6.846 ± 0.072	1.81ValMet: 1.81 ± 0.033	3.192ValAsn: 3.192 ± 0.045	2.875ValPro: 2.875 ± 0.039	2.434ValGln: 2.434 ± 0.034	3.17ValArg: 3.17 ± 0.047	5.044ValSer: 5.044 ± 0.061	4.849ValThr: 4.849 ± 0.099	5.057ValVal: 5.057 ± 0.066	0.876ValTrp: 0.876 ± 0.025	2.359ValTyr: 2.359 ± 0.032	0.0ValXaa: 0.0 ± 0.0
Trp	0.898TrpAla: 0.898 ± 0.024	0.108TrpCys: 0.108 ± 0.012	0.732TrpAsp: 0.732 ± 0.022	0.767TrpGlu: 0.767 ± 0.022	0.597TrpPhe: 0.597 ± 0.019	0.909TrpGly: 0.909 ± 0.03	0.279TrpHis: 0.279 ± 0.012	0.984TrpIle: 0.984 ± 0.025	0.825TrpLys: 0.825 ± 0.02	1.438TrpLeu: 1.438 ± 0.029	0.396TrpMet: 0.396 ± 0.015	0.8TrpAsn: 0.8 ± 0.023	0.372TrpPro: 0.372 ± 0.014	0.489TrpGln: 0.489 ± 0.014	0.643TrpArg: 0.643 ± 0.021	0.954TrpSer: 0.954 ± 0.024	0.777TrpThr: 0.777 ± 0.023	0.882TrpVal: 0.882 ± 0.021	0.185TrpTrp: 0.185 ± 0.01	0.448TrpTyr: 0.448 ± 0.017	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.523TyrAla: 2.523 ± 0.039	0.299TyrCys: 0.299 ± 0.011	1.931TyrAsp: 1.931 ± 0.03	2.314TyrGlu: 2.314 ± 0.035	1.642TyrPhe: 1.642 ± 0.032	2.678TyrGly: 2.678 ± 0.036	0.727TyrHis: 0.727 ± 0.021	2.19TyrIle: 2.19 ± 0.034	1.712TyrLys: 1.712 ± 0.029	3.448TyrLeu: 3.448 ± 0.046	0.896TyrMet: 0.896 ± 0.023	1.591TyrAsn: 1.591 ± 0.031	1.53TyrPro: 1.53 ± 0.028	1.165TyrGln: 1.165 ± 0.026	1.981TyrArg: 1.981 ± 0.037	2.448TyrSer: 2.448 ± 0.036	1.935TyrThr: 1.935 ± 0.036	2.369TyrVal: 2.369 ± 0.038	0.531TyrTrp: 0.531 ± 0.032	1.47TyrTyr: 1.47 ± 0.029	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 6200 proteins (2032609 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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