Amino acid dipepetide frequency for Lukuni virus

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
2.057AlaAla: 2.057 ± 0.848
1.028AlaCys: 1.028 ± 0.288
2.057AlaAsp: 2.057 ± 0.786
2.571AlaGlu: 2.571 ± 1.322
1.285AlaPhe: 1.285 ± 0.473
3.342AlaGly: 3.342 ± 1.194
1.028AlaHis: 1.028 ± 0.721
3.599AlaIle: 3.599 ± 1.145
4.37AlaLys: 4.37 ± 1.104
3.599AlaLeu: 3.599 ± 1.145
1.799AlaMet: 1.799 ± 0.786
4.37AlaAsn: 4.37 ± 1.357
1.799AlaPro: 1.799 ± 2.478
1.028AlaGln: 1.028 ± 0.721
1.542AlaArg: 1.542 ± 1.565
2.828AlaSer: 2.828 ± 1.537
1.799AlaThr: 1.799 ± 0.55
1.799AlaVal: 1.799 ± 0.55
0.0AlaTrp: 0.0 ± 0.0
2.828AlaTyr: 2.828 ± 0.91
0.0AlaXaa: 0.0 ± 0.0
Cys
1.285CysAla: 1.285 ± 0.683
0.514CysCys: 0.514 ± 0.144
1.799CysAsp: 1.799 ± 0.947
2.057CysGlu: 2.057 ± 0.848
2.314CysPhe: 2.314 ± 1.074
2.314CysGly: 2.314 ± 1.772
1.028CysHis: 1.028 ± 0.59
1.799CysIle: 1.799 ± 0.629
2.314CysLys: 2.314 ± 1.772
2.571CysLeu: 2.571 ± 0.694
0.257CysMet: 0.257 ± 0.237
0.257CysAsn: 0.257 ± 0.161
0.771CysPro: 0.771 ± 0.358
2.314CysGln: 2.314 ± 0.563
1.285CysArg: 1.285 ± 1.187
1.285CysSer: 1.285 ± 0.298
1.542CysThr: 1.542 ± 1.062
1.028CysVal: 1.028 ± 0.95
0.514CysTrp: 0.514 ± 0.144
1.285CysTyr: 1.285 ± 0.491
0.0CysXaa: 0.0 ± 0.0
Asp
1.542AspAla: 1.542 ± 0.431
2.057AspCys: 2.057 ± 0.575
4.37AspAsp: 4.37 ± 0.94
5.141AspGlu: 5.141 ± 0.566
4.627AspPhe: 4.627 ± 1.435
1.799AspGly: 1.799 ± 0.786
1.028AspHis: 1.028 ± 0.288
6.941AspIle: 6.941 ± 1.893
3.085AspLys: 3.085 ± 0.52
4.884AspLeu: 4.884 ± 1.139
2.314AspMet: 2.314 ± 0.575
2.828AspAsn: 2.828 ± 0.311
2.314AspPro: 2.314 ± 0.878
1.542AspGln: 1.542 ± 0.604
1.285AspArg: 1.285 ± 0.804
3.085AspSer: 3.085 ± 0.766
1.285AspThr: 1.285 ± 0.298
2.314AspVal: 2.314 ± 0.575
0.514AspTrp: 0.514 ± 0.884
2.828AspTyr: 2.828 ± 1.111
0.0AspXaa: 0.0 ± 0.0
Glu
1.799GluAla: 1.799 ± 0.629
0.771GluCys: 0.771 ± 0.192
2.314GluAsp: 2.314 ± 0.563
4.113GluGlu: 4.113 ± 0.46
4.884GluPhe: 4.884 ± 0.173
1.542GluGly: 1.542 ± 0.383
1.542GluHis: 1.542 ± 0.431
6.17GluIle: 6.17 ± 0.471
3.856GluLys: 3.856 ± 0.613
5.398GluLeu: 5.398 ± 1.08
2.828GluMet: 2.828 ± 0.434
3.599GluAsn: 3.599 ± 1.012
1.799GluPro: 1.799 ± 0.786
2.314GluGln: 2.314 ± 0.423
3.599GluArg: 3.599 ± 1.012
4.37GluSer: 4.37 ± 0.692
5.398GluThr: 5.398 ± 1.255
3.085GluVal: 3.085 ± 1.364
0.514GluTrp: 0.514 ± 0.322
2.314GluTyr: 2.314 ± 0.575
0.0GluXaa: 0.0 ± 0.0
Phe
0.771PheAla: 0.771 ± 0.82
1.285PheCys: 1.285 ± 0.491
3.342PheAsp: 3.342 ± 1.637
4.37PheGlu: 4.37 ± 1.019
2.571PhePhe: 2.571 ± 1.322
2.057PheGly: 2.057 ± 0.539
0.771PheHis: 0.771 ± 0.482
4.37PheIle: 4.37 ± 0.829
4.627PheLys: 4.627 ± 0.846
5.398PheLeu: 5.398 ± 3.688
2.057PheMet: 2.057 ± 0.575
3.599PheAsn: 3.599 ± 0.856
1.285PhePro: 1.285 ± 0.693
0.514PheGln: 0.514 ± 0.144
2.314PheArg: 2.314 ± 1.224
3.342PheSer: 3.342 ± 0.294
3.085PheThr: 3.085 ± 0.722
2.828PheVal: 2.828 ± 0.311
0.257PheTrp: 0.257 ± 0.161
1.799PheTyr: 1.799 ± 0.613
0.0PheXaa: 0.0 ± 0.0
Gly
1.799GlyAla: 1.799 ± 0.629
2.314GlyCys: 2.314 ± 1.074
2.057GlyAsp: 2.057 ± 0.646
2.828GlyGlu: 2.828 ± 0.702
1.542GlyPhe: 1.542 ± 1.683
1.285GlyGly: 1.285 ± 1.17
1.542GlyHis: 1.542 ± 0.743
3.085GlyIle: 3.085 ± 1.208
3.085GlyLys: 3.085 ± 0.721
4.37GlyLeu: 4.37 ± 1.876
1.542GlyMet: 1.542 ± 0.383
2.571GlyAsn: 2.571 ± 0.397
1.285GlyPro: 1.285 ± 0.298
1.799GlyGln: 1.799 ± 0.506
1.799GlyArg: 1.799 ± 0.786
1.285GlySer: 1.285 ± 0.298
3.856GlyThr: 3.856 ± 2.537
1.799GlyVal: 1.799 ± 0.55
0.514GlyTrp: 0.514 ± 0.144
1.285GlyTyr: 1.285 ± 0.473
0.0GlyXaa: 0.0 ± 0.0
His
1.028HisAla: 1.028 ± 0.59
0.514HisCys: 0.514 ± 0.144
2.314HisAsp: 2.314 ± 0.563
0.514HisGlu: 0.514 ± 0.144
0.771HisPhe: 0.771 ± 0.192
1.542HisGly: 1.542 ± 0.383
0.771HisHis: 0.771 ± 0.482
1.799HisIle: 1.799 ± 0.613
2.057HisLys: 2.057 ± 0.646
2.314HisLeu: 2.314 ± 1.395
0.514HisMet: 0.514 ± 0.185
1.285HisAsn: 1.285 ± 0.683
1.028HisPro: 1.028 ± 0.288
0.257HisGln: 0.257 ± 0.237
1.028HisArg: 1.028 ± 1.03
1.542HisSer: 1.542 ± 0.431
1.028HisThr: 1.028 ± 0.59
1.799HisVal: 1.799 ± 0.859
0.514HisTrp: 0.514 ± 0.144
1.285HisTyr: 1.285 ± 0.825
0.0HisXaa: 0.0 ± 0.0
Ile
5.398IleAla: 5.398 ± 1.08
3.085IleCys: 3.085 ± 1.771
6.684IleAsp: 6.684 ± 1.977
5.398IleGlu: 5.398 ± 0.306
3.599IlePhe: 3.599 ± 0.768
4.627IleGly: 4.627 ± 1.682
2.571IleHis: 2.571 ± 0.596
5.656IleIle: 5.656 ± 0.356
7.455IleLys: 7.455 ± 1.985
7.712IleLeu: 7.712 ± 0.836
1.799IleMet: 1.799 ± 0.718
5.398IleAsn: 5.398 ± 1.341
3.342IlePro: 3.342 ± 0.294
2.828IleGln: 2.828 ± 1.101
1.799IleArg: 1.799 ± 0.859
5.656IleSer: 5.656 ± 1.317
5.398IleThr: 5.398 ± 1.519
3.856IleVal: 3.856 ± 0.894
0.771IleTrp: 0.771 ± 0.192
3.856IleTyr: 3.856 ± 0.985
0.0IleXaa: 0.0 ± 0.0
Lys
4.113LysAla: 4.113 ± 2.103
3.599LysCys: 3.599 ± 1.894
4.37LysAsp: 4.37 ± 2.034
5.913LysGlu: 5.913 ± 1.795
3.085LysPhe: 3.085 ± 2.269
3.342LysGly: 3.342 ± 1.194
1.799LysHis: 1.799 ± 0.629
6.941LysIle: 6.941 ± 1.841
4.884LysLys: 4.884 ± 0.813
5.913LysLeu: 5.913 ± 1.577
2.057LysMet: 2.057 ± 0.552
4.627LysAsn: 4.627 ± 1.073
1.542LysPro: 1.542 ± 0.383
2.571LysGln: 2.571 ± 0.651
2.828LysArg: 2.828 ± 0.753
6.17LysSer: 6.17 ± 1.253
5.913LysThr: 5.913 ± 1.049
5.398LysVal: 5.398 ± 0.816
1.028LysTrp: 1.028 ± 0.323
3.085LysTyr: 3.085 ± 1.085
0.0LysXaa: 0.0 ± 0.0
Leu
4.37LeuAla: 4.37 ± 1.914
1.542LeuCys: 1.542 ± 1.424
6.427LeuAsp: 6.427 ± 1.839
4.113LeuGlu: 4.113 ± 1.166
4.37LeuPhe: 4.37 ± 0.087
2.828LeuGly: 2.828 ± 1.625
1.285LeuHis: 1.285 ± 1.658
6.941LeuIle: 6.941 ± 1.626
6.427LeuLys: 6.427 ± 1.392
10.026LeuLeu: 10.026 ± 0.424
2.828LeuMet: 2.828 ± 1.29
4.884LeuAsn: 4.884 ± 0.96
3.342LeuPro: 3.342 ± 0.776
3.085LeuGln: 3.085 ± 0.722
2.828LeuArg: 2.828 ± 0.753
10.797LeuSer: 10.797 ± 1.632
7.455LeuThr: 7.455 ± 0.927
4.627LeuVal: 4.627 ± 1.121
0.771LeuTrp: 0.771 ± 0.192
3.342LeuTyr: 3.342 ± 0.883
0.0LeuXaa: 0.0 ± 0.0
Met
1.542MetAla: 1.542 ± 0.383
1.285MetCys: 1.285 ± 0.491
1.542MetAsp: 1.542 ± 0.604
2.314MetGlu: 2.314 ± 1.104
0.257MetPhe: 0.257 ± 0.161
0.257MetGly: 0.257 ± 0.161
0.771MetHis: 0.771 ± 0.358
3.342MetIle: 3.342 ± 0.843
2.057MetLys: 2.057 ± 1.442
3.085MetLeu: 3.085 ± 0.386
0.257MetMet: 0.257 ± 0.161
1.028MetAsn: 1.028 ± 0.643
1.542MetPro: 1.542 ± 0.923
0.514MetGln: 0.514 ± 0.144
3.342MetArg: 3.342 ± 0.883
2.057MetSer: 2.057 ± 0.707
2.057MetThr: 2.057 ± 1.442
1.799MetVal: 1.799 ± 0.427
0.257MetTrp: 0.257 ± 0.161
2.314MetTyr: 2.314 ± 0.56
0.0MetXaa: 0.0 ± 0.0
Asn
3.599AsnAla: 3.599 ± 1.099
2.314AsnCys: 2.314 ± 1.415
3.085AsnAsp: 3.085 ± 1.257
2.571AsnGlu: 2.571 ± 0.596
3.085AsnPhe: 3.085 ± 1.615
0.771AsnGly: 0.771 ± 0.192
1.542AsnHis: 1.542 ± 0.383
4.627AsnIle: 4.627 ± 0.608
3.085AsnLys: 3.085 ± 0.969
6.17AsnLeu: 6.17 ± 1.44
1.799AsnMet: 1.799 ± 1.125
2.314AsnAsn: 2.314 ± 0.794
2.828AsnPro: 2.828 ± 0.434
1.542AsnGln: 1.542 ± 0.965
2.314AsnArg: 2.314 ± 0.423
3.342AsnSer: 3.342 ± 1.379
2.314AsnThr: 2.314 ± 0.56
2.571AsnVal: 2.571 ± 1.042
0.514AsnTrp: 0.514 ± 0.322
3.342AsnTyr: 3.342 ± 0.883
0.0AsnXaa: 0.0 ± 0.0
Pro
1.542ProAla: 1.542 ± 1.565
0.771ProCys: 0.771 ± 0.93
2.314ProAsp: 2.314 ± 0.878
2.571ProGlu: 2.571 ± 0.397
1.799ProPhe: 1.799 ± 0.786
1.799ProGly: 1.799 ± 1.637
0.771ProHis: 0.771 ± 0.93
2.828ProIle: 2.828 ± 0.827
2.314ProLys: 2.314 ± 0.769
4.113ProLeu: 4.113 ± 1.945
1.285ProMet: 1.285 ± 0.298
0.771ProAsn: 0.771 ± 0.482
0.257ProPro: 0.257 ± 0.161
1.285ProGln: 1.285 ± 0.491
1.285ProArg: 1.285 ± 0.491
2.828ProSer: 2.828 ± 0.667
1.799ProThr: 1.799 ± 0.947
1.799ProVal: 1.799 ± 0.427
0.257ProTrp: 0.257 ± 0.161
1.028ProTyr: 1.028 ± 0.323
0.0ProXaa: 0.0 ± 0.0
Gln
1.285GlnAla: 1.285 ± 0.683
1.542GlnCys: 1.542 ± 0.716
1.285GlnAsp: 1.285 ± 0.804
1.285GlnGlu: 1.285 ± 0.683
1.542GlnPhe: 1.542 ± 0.743
2.057GlnGly: 2.057 ± 0.646
0.771GlnHis: 0.771 ± 0.358
4.113GlnIle: 4.113 ± 1.073
4.627GlnLys: 4.627 ± 0.936
1.542GlnLeu: 1.542 ± 0.716
0.771GlnMet: 0.771 ± 0.712
2.314GlnAsn: 2.314 ± 1.104
0.771GlnPro: 0.771 ± 0.82
1.285GlnGln: 1.285 ± 0.693
1.799GlnArg: 1.799 ± 0.718
2.057GlnSer: 2.057 ± 0.945
2.314GlnThr: 2.314 ± 0.575
1.542GlnVal: 1.542 ± 0.431
0.0GlnTrp: 0.0 ± 0.0
1.542GlnTyr: 1.542 ± 0.383
0.0GlnXaa: 0.0 ± 0.0
Arg
2.057ArgAla: 2.057 ± 0.48
1.028ArgCys: 1.028 ± 0.288
1.799ArgAsp: 1.799 ± 0.786
3.085ArgGlu: 3.085 ± 0.873
2.057ArgPhe: 2.057 ± 0.945
0.771ArgGly: 0.771 ± 0.192
1.028ArgHis: 1.028 ± 0.643
3.599ArgIle: 3.599 ± 0.399
4.37ArgLys: 4.37 ± 0.829
3.342ArgLeu: 3.342 ± 0.843
1.285ArgMet: 1.285 ± 0.681
2.571ArgAsn: 2.571 ± 0.694
1.542ArgPro: 1.542 ± 0.716
1.028ArgGln: 1.028 ± 0.804
1.028ArgArg: 1.028 ± 0.323
2.571ArgSer: 2.571 ± 0.694
3.342ArgThr: 3.342 ± 1.216
2.057ArgVal: 2.057 ± 1.608
0.257ArgTrp: 0.257 ± 0.161
2.314ArgTyr: 2.314 ± 0.878
0.0ArgXaa: 0.0 ± 0.0
Ser
3.085SerAla: 3.085 ± 1.301
1.542SerCys: 1.542 ± 0.716
4.627SerAsp: 4.627 ± 1.149
3.599SerGlu: 3.599 ± 1.012
3.085SerPhe: 3.085 ± 0.722
3.085SerGly: 3.085 ± 1.085
1.285SerHis: 1.285 ± 0.825
6.427SerIle: 6.427 ± 0.545
6.427SerLys: 6.427 ± 0.529
7.198SerLeu: 7.198 ± 0.798
2.571SerMet: 2.571 ± 0.651
2.057SerAsn: 2.057 ± 0.502
2.571SerPro: 2.571 ± 0.397
3.085SerGln: 3.085 ± 1.257
4.627SerArg: 4.627 ± 0.608
5.656SerSer: 5.656 ± 2.201
5.913SerThr: 5.913 ± 1.766
4.113SerVal: 4.113 ± 0.989
0.0SerTrp: 0.0 ± 0.0
2.314SerTyr: 2.314 ± 0.56
0.0SerXaa: 0.0 ± 0.0
Thr
3.342ThrAla: 3.342 ± 1.144
1.028ThrCys: 1.028 ± 0.288
2.571ThrAsp: 2.571 ± 0.596
4.113ThrGlu: 4.113 ± 0.46
3.342ThrPhe: 3.342 ± 1.391
2.828ThrGly: 2.828 ± 1.205
1.028ThrHis: 1.028 ± 0.721
6.17ThrIle: 6.17 ± 1.445
5.913ThrLys: 5.913 ± 1.577
6.17ThrLeu: 6.17 ± 2.463
0.771ThrMet: 0.771 ± 0.79
2.828ThrAsn: 2.828 ± 0.91
2.571ThrPro: 2.571 ± 0.596
2.314ThrGln: 2.314 ± 0.563
2.571ThrArg: 2.571 ± 0.694
6.17ThrSer: 6.17 ± 0.913
4.37ThrThr: 4.37 ± 1.07
2.828ThrVal: 2.828 ± 0.434
1.285ThrTrp: 1.285 ± 0.883
3.342ThrTyr: 3.342 ± 0.843
0.0ThrXaa: 0.0 ± 0.0
Val
2.571ValAla: 2.571 ± 0.699
1.285ValCys: 1.285 ± 0.298
1.542ValAsp: 1.542 ± 1.683
3.085ValGlu: 3.085 ± 0.722
3.599ValPhe: 3.599 ± 2.08
2.314ValGly: 2.314 ± 0.575
1.799ValHis: 1.799 ± 0.427
4.113ValIle: 4.113 ± 0.989
4.37ValLys: 4.37 ± 1.037
3.599ValLeu: 3.599 ± 1.006
2.314ValMet: 2.314 ± 0.575
1.542ValAsn: 1.542 ± 0.604
1.542ValPro: 1.542 ± 0.431
3.085ValGln: 3.085 ± 1.231
0.514ValArg: 0.514 ± 0.322
3.856ValSer: 3.856 ± 1.025
3.856ValThr: 3.856 ± 1.998
1.799ValVal: 1.799 ± 1.504
0.0ValTrp: 0.0 ± 0.0
2.314ValTyr: 2.314 ± 0.769
0.0ValXaa: 0.0 ± 0.0
Trp
0.514TrpAla: 0.514 ± 0.144
0.257TrpCys: 0.257 ± 0.161
0.514TrpAsp: 0.514 ± 0.144
0.514TrpGlu: 0.514 ± 0.322
0.771TrpPhe: 0.771 ± 0.192
0.514TrpGly: 0.514 ± 0.475
0.257TrpHis: 0.257 ± 0.237
0.514TrpIle: 0.514 ± 0.144
0.514TrpLys: 0.514 ± 0.475
1.028TrpLeu: 1.028 ± 0.825
0.771TrpMet: 0.771 ± 0.79
0.514TrpAsn: 0.514 ± 0.322
0.0TrpPro: 0.0 ± 0.0
0.0TrpGln: 0.0 ± 0.0
0.514TrpArg: 0.514 ± 0.322
1.285TrpSer: 1.285 ± 0.804
0.0TrpThr: 0.0 ± 0.0
0.0TrpVal: 0.0 ± 0.0
0.0TrpTrp: 0.0 ± 0.0
0.0TrpTyr: 0.0 ± 0.0
0.0TrpXaa: 0.0 ± 0.0
Tyr
1.028TyrAla: 1.028 ± 0.288
0.771TyrCys: 0.771 ± 0.358
0.771TyrAsp: 0.771 ± 0.192
2.057TyrGlu: 2.057 ± 0.48
2.057TyrPhe: 2.057 ± 0.945
2.571TyrGly: 2.571 ± 0.699
1.285TyrHis: 1.285 ± 1.187
3.856TyrIle: 3.856 ± 0.894
3.599TyrLys: 3.599 ± 1.258
3.856TyrLeu: 3.856 ± 0.239
1.542TyrMet: 1.542 ± 0.383
4.37TyrAsn: 4.37 ± 1.439
1.285TyrPro: 1.285 ± 0.883
2.057TyrGln: 2.057 ± 0.48
2.828TyrArg: 2.828 ± 0.91
3.085TyrSer: 3.085 ± 0.386
2.828TyrThr: 2.828 ± 1.423
2.057TyrVal: 2.057 ± 1.479
0.514TyrTrp: 0.514 ± 0.322
1.028TyrTyr: 1.028 ± 0.288
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 3 proteins (3891 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski