Amino acid dipepetide frequency for Venustampulla echinocandica

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	8.672AlaAla: 8.672 ± 0.064	1.033AlaCys: 1.033 ± 0.013	4.099AlaAsp: 4.099 ± 0.03	5.045AlaGlu: 5.045 ± 0.043	3.043AlaPhe: 3.043 ± 0.025	5.671AlaGly: 5.671 ± 0.034	1.682AlaHis: 1.682 ± 0.019	4.487AlaIle: 4.487 ± 0.032	4.227AlaLys: 4.227 ± 0.035	7.612AlaLeu: 7.612 ± 0.042	1.963AlaMet: 1.963 ± 0.022	3.025AlaAsn: 3.025 ± 0.025	4.779AlaPro: 4.779 ± 0.043	3.269AlaGln: 3.269 ± 0.027	4.622AlaArg: 4.622 ± 0.033	7.145AlaSer: 7.145 ± 0.038	5.306AlaThr: 5.306 ± 0.033	5.131AlaVal: 5.131 ± 0.034	1.095AlaTrp: 1.095 ± 0.018	2.092AlaTyr: 2.092 ± 0.018	0.0AlaXaa: 0.0 ± 0.0
Cys	0.879CysAla: 0.879 ± 0.014	0.23CysCys: 0.23 ± 0.007	0.631CysAsp: 0.631 ± 0.011	0.593CysGlu: 0.593 ± 0.012	0.522CysPhe: 0.522 ± 0.012	0.94CysGly: 0.94 ± 0.014	0.315CysHis: 0.315 ± 0.008	0.724CysIle: 0.724 ± 0.013	0.551CysLys: 0.551 ± 0.011	1.203CysLeu: 1.203 ± 0.019	0.255CysMet: 0.255 ± 0.007	0.45CysAsn: 0.45 ± 0.008	0.666CysPro: 0.666 ± 0.014	0.437CysGln: 0.437 ± 0.009	0.721CysArg: 0.721 ± 0.012	0.941CysSer: 0.941 ± 0.017	0.695CysThr: 0.695 ± 0.011	0.779CysVal: 0.779 ± 0.015	0.206CysTrp: 0.206 ± 0.005	0.375CysTyr: 0.375 ± 0.008	0.0CysXaa: 0.0 ± 0.0
Asp	4.404AspAla: 4.404 ± 0.032	0.617AspCys: 0.617 ± 0.014	4.113AspAsp: 4.113 ± 0.039	4.408AspGlu: 4.408 ± 0.037	2.185AspPhe: 2.185 ± 0.021	4.132AspGly: 4.132 ± 0.032	1.213AspHis: 1.213 ± 0.02	3.355AspIle: 3.355 ± 0.026	2.38AspLys: 2.38 ± 0.024	5.0AspLeu: 5.0 ± 0.031	1.295AspMet: 1.295 ± 0.014	1.955AspAsn: 1.955 ± 0.017	3.292AspPro: 3.292 ± 0.024	1.845AspGln: 1.845 ± 0.019	2.878AspArg: 2.878 ± 0.026	4.182AspSer: 4.182 ± 0.029	2.937AspThr: 2.937 ± 0.026	3.554AspVal: 3.554 ± 0.025	0.864AspTrp: 0.864 ± 0.013	1.545AspTyr: 1.545 ± 0.018	0.0AspXaa: 0.0 ± 0.0
Glu	5.303GluAla: 5.303 ± 0.042	0.629GluCys: 0.629 ± 0.012	4.212GluAsp: 4.212 ± 0.038	5.342GluGlu: 5.342 ± 0.057	1.979GluPhe: 1.979 ± 0.019	3.937GluGly: 3.937 ± 0.032	1.349GluHis: 1.349 ± 0.017	3.279GluIle: 3.279 ± 0.029	3.784GluLys: 3.784 ± 0.034	5.216GluLeu: 5.216 ± 0.039	1.487GluMet: 1.487 ± 0.017	2.405GluAsn: 2.405 ± 0.023	2.782GluPro: 2.782 ± 0.032	2.378GluGln: 2.378 ± 0.026	3.838GluArg: 3.838 ± 0.038	4.352GluSer: 4.352 ± 0.031	3.383GluThr: 3.383 ± 0.028	3.694GluVal: 3.694 ± 0.029	0.878GluTrp: 0.878 ± 0.013	1.663GluTyr: 1.663 ± 0.019	0.0GluXaa: 0.0 ± 0.0
Phe	2.95PheAla: 2.95 ± 0.028	0.558PheCys: 0.558 ± 0.009	2.289PheAsp: 2.289 ± 0.022	2.186PheGlu: 2.186 ± 0.02	1.487PhePhe: 1.487 ± 0.02	2.872PheGly: 2.872 ± 0.028	0.851PheHis: 0.851 ± 0.012	1.847PheIle: 1.847 ± 0.022	1.607PheLys: 1.607 ± 0.018	3.337PheLeu: 3.337 ± 0.031	0.781PheMet: 0.781 ± 0.014	1.485PheAsn: 1.485 ± 0.015	1.977PhePro: 1.977 ± 0.023	1.441PheGln: 1.441 ± 0.017	1.852PheArg: 1.852 ± 0.02	2.989PheSer: 2.989 ± 0.026	2.155PheThr: 2.155 ± 0.023	2.299PheVal: 2.299 ± 0.023	0.607PheTrp: 0.607 ± 0.011	1.057PheTyr: 1.057 ± 0.016	0.0PheXaa: 0.0 ± 0.0
Gly	5.361GlyAla: 5.361 ± 0.04	0.883GlyCys: 0.883 ± 0.014	3.764GlyAsp: 3.764 ± 0.029	3.743GlyGlu: 3.743 ± 0.034	2.8GlyPhe: 2.8 ± 0.031	6.04GlyGly: 6.04 ± 0.058	1.665GlyHis: 1.665 ± 0.019	3.744GlyIle: 3.744 ± 0.03	3.726GlyLys: 3.726 ± 0.03	6.043GlyLeu: 6.043 ± 0.038	1.675GlyMet: 1.675 ± 0.018	2.8GlyAsn: 2.8 ± 0.028	3.447GlyPro: 3.447 ± 0.029	2.512GlyGln: 2.512 ± 0.026	4.12GlyArg: 4.12 ± 0.035	5.854GlySer: 5.854 ± 0.04	4.051GlyThr: 4.051 ± 0.032	4.333GlyVal: 4.333 ± 0.03	1.148GlyTrp: 1.148 ± 0.016	2.141GlyTyr: 2.141 ± 0.026	0.0GlyXaa: 0.0 ± 0.0
His	1.703HisAla: 1.703 ± 0.022	0.311HisCys: 0.311 ± 0.008	1.241HisAsp: 1.241 ± 0.017	1.266HisGlu: 1.266 ± 0.016	0.887HisPhe: 0.887 ± 0.014	1.672HisGly: 1.672 ± 0.019	0.791HisHis: 0.791 ± 0.016	1.267HisIle: 1.267 ± 0.017	0.947HisLys: 0.947 ± 0.014	2.14HisLeu: 2.14 ± 0.021	0.471HisMet: 0.471 ± 0.011	0.89HisAsn: 0.89 ± 0.014	1.664HisPro: 1.664 ± 0.02	0.982HisGln: 0.982 ± 0.014	1.445HisArg: 1.445 ± 0.016	1.808HisSer: 1.808 ± 0.019	1.253HisThr: 1.253 ± 0.017	1.302HisVal: 1.302 ± 0.016	0.322HisTrp: 0.322 ± 0.007	0.664HisTyr: 0.664 ± 0.011	0.0HisXaa: 0.0 ± 0.0
Ile	4.298IleAla: 4.298 ± 0.033	0.783IleCys: 0.783 ± 0.014	2.986IleAsp: 2.986 ± 0.023	3.033IleGlu: 3.033 ± 0.03	2.094IlePhe: 2.094 ± 0.023	3.386IleGly: 3.386 ± 0.029	1.23IleHis: 1.23 ± 0.015	2.78IleIle: 2.78 ± 0.026	2.443IleLys: 2.443 ± 0.024	4.777IleLeu: 4.777 ± 0.032	1.065IleMet: 1.065 ± 0.014	1.954IleAsn: 1.954 ± 0.02	3.321IlePro: 3.321 ± 0.03	2.026IleGln: 2.026 ± 0.019	2.811IleArg: 2.811 ± 0.024	4.366IleSer: 4.366 ± 0.03	3.057IleThr: 3.057 ± 0.025	3.206IleVal: 3.206 ± 0.03	0.752IleTrp: 0.752 ± 0.013	1.495IleTyr: 1.495 ± 0.018	0.0IleXaa: 0.0 ± 0.0
Lys	4.436LysAla: 4.436 ± 0.035	0.55LysCys: 0.55 ± 0.011	2.908LysAsp: 2.908 ± 0.028	3.531LysGlu: 3.531 ± 0.035	1.552LysPhe: 1.552 ± 0.018	3.316LysGly: 3.316 ± 0.028	1.144LysHis: 1.144 ± 0.016	2.492LysIle: 2.492 ± 0.026	3.47LysLys: 3.47 ± 0.049	4.324LysLeu: 4.324 ± 0.034	1.061LysMet: 1.061 ± 0.013	1.866LysAsn: 1.866 ± 0.02	2.895LysPro: 2.895 ± 0.028	1.862LysGln: 1.862 ± 0.023	3.417LysArg: 3.417 ± 0.032	3.877LysSer: 3.877 ± 0.033	2.939LysThr: 2.939 ± 0.027	2.937LysVal: 2.937 ± 0.024	0.709LysTrp: 0.709 ± 0.012	1.467LysTyr: 1.467 ± 0.017	0.0LysXaa: 0.0 ± 0.0
Leu	7.681LeuAla: 7.681 ± 0.044	1.184LeuCys: 1.184 ± 0.017	5.14LeuAsp: 5.14 ± 0.032	5.675LeuGlu: 5.675 ± 0.042	3.177LeuPhe: 3.177 ± 0.029	5.964LeuGly: 5.964 ± 0.036	2.121LeuHis: 2.121 ± 0.022	3.996LeuIle: 3.996 ± 0.032	4.484LeuLys: 4.484 ± 0.033	8.261LeuLeu: 8.261 ± 0.055	1.751LeuMet: 1.751 ± 0.018	3.263LeuAsn: 3.263 ± 0.027	5.552LeuPro: 5.552 ± 0.037	3.881LeuGln: 3.881 ± 0.035	5.507LeuArg: 5.507 ± 0.038	7.26LeuSer: 7.26 ± 0.039	4.724LeuThr: 4.724 ± 0.032	5.271LeuVal: 5.271 ± 0.037	1.161LeuTrp: 1.161 ± 0.016	2.289LeuTyr: 2.289 ± 0.022	0.0LeuXaa: 0.0 ± 0.0
Met	2.263MetAla: 2.263 ± 0.02	0.233MetCys: 0.233 ± 0.007	1.3MetAsp: 1.3 ± 0.014	1.358MetGlu: 1.358 ± 0.016	0.736MetPhe: 0.736 ± 0.012	1.522MetGly: 1.522 ± 0.02	0.458MetHis: 0.458 ± 0.009	1.023MetIle: 1.023 ± 0.015	1.091MetLys: 1.091 ± 0.015	1.825MetLeu: 1.825 ± 0.019	0.565MetMet: 0.565 ± 0.011	0.822MetAsn: 0.822 ± 0.012	1.27MetPro: 1.27 ± 0.016	0.845MetGln: 0.845 ± 0.012	1.22MetArg: 1.22 ± 0.016	1.889MetSer: 1.889 ± 0.019	1.229MetThr: 1.229 ± 0.015	1.298MetVal: 1.298 ± 0.016	0.253MetTrp: 0.253 ± 0.007	0.514MetTyr: 0.514 ± 0.011	0.0MetXaa: 0.0 ± 0.0
Asn	3.136AsnAla: 3.136 ± 0.023	0.486AsnCys: 0.486 ± 0.011	2.028AsnAsp: 2.028 ± 0.021	2.076AsnGlu: 2.076 ± 0.021	1.455AsnPhe: 1.455 ± 0.017	3.174AsnGly: 3.174 ± 0.033	0.883AsnHis: 0.883 ± 0.014	2.303AsnIle: 2.303 ± 0.022	1.66AsnLys: 1.66 ± 0.02	3.39AsnLeu: 3.39 ± 0.028	0.873AsnMet: 0.873 ± 0.014	1.619AsnAsn: 1.619 ± 0.021	2.654AsnPro: 2.654 ± 0.025	1.394AsnGln: 1.394 ± 0.018	1.968AsnArg: 1.968 ± 0.02	3.089AsnSer: 3.089 ± 0.028	2.345AsnThr: 2.345 ± 0.021	2.28AsnVal: 2.28 ± 0.021	0.561AsnTrp: 0.561 ± 0.01	1.072AsnTyr: 1.072 ± 0.014	0.0AsnXaa: 0.0 ± 0.0
Pro	5.078ProAla: 5.078 ± 0.044	0.502ProCys: 0.502 ± 0.01	3.089ProAsp: 3.089 ± 0.025	3.793ProGlu: 3.793 ± 0.033	2.048ProPhe: 2.048 ± 0.018	4.015ProGly: 4.015 ± 0.032	1.328ProHis: 1.328 ± 0.016	2.828ProIle: 2.828 ± 0.024	2.92ProLys: 2.92 ± 0.03	4.82ProLeu: 4.82 ± 0.03	1.069ProMet: 1.069 ± 0.016	2.389ProAsn: 2.389 ± 0.025	5.362ProPro: 5.362 ± 0.071	2.615ProGln: 2.615 ± 0.027	3.374ProArg: 3.374 ± 0.026	6.305ProSer: 6.305 ± 0.048	4.251ProThr: 4.251 ± 0.04	3.443ProVal: 3.443 ± 0.03	0.725ProTrp: 0.725 ± 0.012	1.494ProTyr: 1.494 ± 0.018	0.0ProXaa: 0.0 ± 0.0
Gln	3.338GlnAla: 3.338 ± 0.026	0.437GlnCys: 0.437 ± 0.01	2.055GlnAsp: 2.055 ± 0.023	2.394GlnGlu: 2.394 ± 0.021	1.308GlnPhe: 1.308 ± 0.017	2.408GlnGly: 2.408 ± 0.025	1.033GlnHis: 1.033 ± 0.015	1.969GlnIle: 1.969 ± 0.021	2.055GlnLys: 2.055 ± 0.024	3.471GlnLeu: 3.471 ± 0.03	0.874GlnMet: 0.874 ± 0.016	1.673GlnAsn: 1.673 ± 0.02	2.497GlnPro: 2.497 ± 0.031	2.304GlnGln: 2.304 ± 0.04	2.558GlnArg: 2.558 ± 0.026	3.136GlnSer: 3.136 ± 0.025	2.302GlnThr: 2.302 ± 0.021	2.16GlnVal: 2.16 ± 0.024	0.537GlnTrp: 0.537 ± 0.01	1.18GlnTyr: 1.18 ± 0.018	0.0GlnXaa: 0.0 ± 0.0
Arg	4.456ArgAla: 4.456 ± 0.033	0.679ArgCys: 0.679 ± 0.014	3.233ArgAsp: 3.233 ± 0.031	3.752ArgGlu: 3.752 ± 0.032	2.021ArgPhe: 2.021 ± 0.023	3.796ArgGly: 3.796 ± 0.035	1.445ArgHis: 1.445 ± 0.016	2.926ArgIle: 2.926 ± 0.024	3.482ArgLys: 3.482 ± 0.031	5.17ArgLeu: 5.17 ± 0.044	1.268ArgMet: 1.268 ± 0.019	2.315ArgAsn: 2.315 ± 0.022	3.428ArgPro: 3.428 ± 0.031	2.482ArgGln: 2.482 ± 0.026	4.765ArgArg: 4.765 ± 0.049	4.728ArgSer: 4.728 ± 0.044	3.187ArgThr: 3.187 ± 0.025	3.194ArgVal: 3.194 ± 0.022	0.865ArgTrp: 0.865 ± 0.014	1.588ArgTyr: 1.588 ± 0.018	0.0ArgXaa: 0.0 ± 0.0
Ser	6.53SerAla: 6.53 ± 0.036	0.894SerCys: 0.894 ± 0.015	4.183SerAsp: 4.183 ± 0.031	4.208SerGlu: 4.208 ± 0.03	3.02SerPhe: 3.02 ± 0.029	5.7SerGly: 5.7 ± 0.035	1.941SerHis: 1.941 ± 0.022	4.374SerIle: 4.374 ± 0.033	4.113SerLys: 4.113 ± 0.031	7.221SerLeu: 7.221 ± 0.045	1.789SerMet: 1.789 ± 0.019	3.367SerAsn: 3.367 ± 0.028	5.829SerPro: 5.829 ± 0.056	3.409SerGln: 3.409 ± 0.031	4.974SerArg: 4.974 ± 0.037	9.146SerSer: 9.146 ± 0.073	5.842SerThr: 5.842 ± 0.043	4.429SerVal: 4.429 ± 0.034	1.13SerTrp: 1.13 ± 0.015	2.131SerTyr: 2.131 ± 0.021	0.0SerXaa: 0.0 ± 0.0
Thr	5.178ThrAla: 5.178 ± 0.031	0.738ThrCys: 0.738 ± 0.012	2.753ThrAsp: 2.753 ± 0.023	3.121ThrGlu: 3.121 ± 0.027	2.279ThrPhe: 2.279 ± 0.023	4.178ThrGly: 4.178 ± 0.03	1.256ThrHis: 1.256 ± 0.017	3.299ThrIle: 3.299 ± 0.027	2.826ThrLys: 2.826 ± 0.025	5.254ThrLeu: 5.254 ± 0.034	1.202ThrMet: 1.202 ± 0.013	2.219ThrAsn: 2.219 ± 0.022	4.487ThrPro: 4.487 ± 0.04	2.068ThrGln: 2.068 ± 0.021	3.071ThrArg: 3.071 ± 0.024	5.573ThrSer: 5.573 ± 0.039	4.429ThrThr: 4.429 ± 0.042	3.655ThrVal: 3.655 ± 0.03	0.814ThrTrp: 0.814 ± 0.015	1.594ThrTyr: 1.594 ± 0.02	0.0ThrXaa: 0.0 ± 0.0
Val	5.18ValAla: 5.18 ± 0.033	0.762ValCys: 0.762 ± 0.013	3.638ValAsp: 3.638 ± 0.025	3.983ValGlu: 3.983 ± 0.029	2.309ValPhe: 2.309 ± 0.023	4.116ValGly: 4.116 ± 0.032	1.282ValHis: 1.282 ± 0.015	2.961ValIle: 2.961 ± 0.022	3.007ValLys: 3.007 ± 0.024	5.383ValLeu: 5.383 ± 0.035	1.301ValMet: 1.301 ± 0.016	2.168ValAsn: 2.168 ± 0.022	3.465ValPro: 3.465 ± 0.025	2.278ValGln: 2.278 ± 0.021	3.198ValArg: 3.198 ± 0.022	4.46ValSer: 4.46 ± 0.032	3.388ValThr: 3.388 ± 0.029	4.226ValVal: 4.226 ± 0.034	0.821ValTrp: 0.821 ± 0.013	1.667ValTyr: 1.667 ± 0.019	0.0ValXaa: 0.0 ± 0.0
Trp	1.121TrpAla: 1.121 ± 0.017	0.185TrpCys: 0.185 ± 0.006	0.896TrpAsp: 0.896 ± 0.013	0.852TrpGlu: 0.852 ± 0.015	0.518TrpPhe: 0.518 ± 0.01	0.941TrpGly: 0.941 ± 0.014	0.325TrpHis: 0.325 ± 0.009	0.766TrpIle: 0.766 ± 0.014	0.821TrpLys: 0.821 ± 0.015	1.266TrpLeu: 1.266 ± 0.018	0.347TrpMet: 0.347 ± 0.008	0.634TrpAsn: 0.634 ± 0.011	0.594TrpPro: 0.594 ± 0.011	0.542TrpGln: 0.542 ± 0.01	0.894TrpArg: 0.894 ± 0.014	1.013TrpSer: 1.013 ± 0.015	0.877TrpThr: 0.877 ± 0.013	0.86TrpVal: 0.86 ± 0.013	0.266TrpTrp: 0.266 ± 0.008	0.418TrpTyr: 0.418 ± 0.009	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.03TyrAla: 2.03 ± 0.02	0.421TyrCys: 0.421 ± 0.009	1.596TyrAsp: 1.596 ± 0.016	1.536TyrGlu: 1.536 ± 0.016	1.208TyrPhe: 1.208 ± 0.015	2.071TyrGly: 2.071 ± 0.023	0.716TyrHis: 0.716 ± 0.013	1.443TyrIle: 1.443 ± 0.019	1.157TyrLys: 1.157 ± 0.015	2.628TyrLeu: 2.628 ± 0.021	0.62TyrMet: 0.62 ± 0.012	1.144TyrAsn: 1.144 ± 0.016	1.486TyrPro: 1.486 ± 0.019	1.117TyrGln: 1.117 ± 0.018	1.547TyrArg: 1.547 ± 0.019	2.115TyrSer: 2.115 ± 0.02	1.645TyrThr: 1.645 ± 0.016	1.541TyrVal: 1.541 ± 0.017	0.423TyrTrp: 0.423 ± 0.01	0.899TyrTyr: 0.899 ± 0.015	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 10697 proteins (5497940 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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