Amino acid dipepetide frequency for Paenibacillus polymyxa (strain SC2) (Bacillus polymyxa)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	7.245AlaAla: 7.245 ± 0.095	0.704AlaCys: 0.704 ± 0.022	4.087AlaAsp: 4.087 ± 0.053	5.174AlaGlu: 5.174 ± 0.072	3.026AlaPhe: 3.026 ± 0.046	6.014AlaGly: 6.014 ± 0.073	1.518AlaHis: 1.518 ± 0.036	5.038AlaIle: 5.038 ± 0.065	4.104AlaLys: 4.104 ± 0.06	8.004AlaLeu: 8.004 ± 0.076	2.067AlaMet: 2.067 ± 0.037	2.659AlaAsn: 2.659 ± 0.037	2.489AlaPro: 2.489 ± 0.038	2.873AlaGln: 2.873 ± 0.046	3.328AlaArg: 3.328 ± 0.054	4.915AlaSer: 4.915 ± 0.059	3.795AlaThr: 3.795 ± 0.053	5.999AlaVal: 5.999 ± 0.07	0.917AlaTrp: 0.917 ± 0.025	2.717AlaTyr: 2.717 ± 0.058	0.0AlaXaa: 0.0 ± 0.0
Cys	0.536CysAla: 0.536 ± 0.018	0.121CysCys: 0.121 ± 0.011	0.391CysAsp: 0.391 ± 0.017	0.469CysGlu: 0.469 ± 0.02	0.361CysPhe: 0.361 ± 0.015	0.721CysGly: 0.721 ± 0.023	0.192CysHis: 0.192 ± 0.01	0.599CysIle: 0.599 ± 0.02	0.348CysLys: 0.348 ± 0.017	0.757CysLeu: 0.757 ± 0.025	0.253CysMet: 0.253 ± 0.012	0.312CysAsn: 0.312 ± 0.013	0.35CysPro: 0.35 ± 0.016	0.245CysGln: 0.245 ± 0.012	0.398CysArg: 0.398 ± 0.015	0.593CysSer: 0.593 ± 0.022	0.431CysThr: 0.431 ± 0.017	0.492CysVal: 0.492 ± 0.016	0.096CysTrp: 0.096 ± 0.008	0.3CysTyr: 0.3 ± 0.013	0.0CysXaa: 0.0 ± 0.0
Asp	3.601AspAla: 3.601 ± 0.052	0.429AspCys: 0.429 ± 0.018	2.368AspAsp: 2.368 ± 0.044	3.843AspGlu: 3.843 ± 0.056	2.203AspPhe: 2.203 ± 0.037	3.741AspGly: 3.741 ± 0.058	1.312AspHis: 1.312 ± 0.027	3.841AspIle: 3.841 ± 0.056	2.816AspLys: 2.816 ± 0.056	4.914AspLeu: 4.914 ± 0.083	1.455AspMet: 1.455 ± 0.033	1.772AspAsn: 1.772 ± 0.033	2.176AspPro: 2.176 ± 0.036	2.171AspGln: 2.171 ± 0.031	2.672AspArg: 2.672 ± 0.043	2.923AspSer: 2.923 ± 0.048	2.734AspThr: 2.734 ± 0.043	3.598AspVal: 3.598 ± 0.05	0.784AspTrp: 0.784 ± 0.023	2.071AspTyr: 2.071 ± 0.037	0.0AspXaa: 0.0 ± 0.0
Glu	5.645GluAla: 5.645 ± 0.073	0.439GluCys: 0.439 ± 0.018	3.339GluAsp: 3.339 ± 0.049	5.453GluGlu: 5.453 ± 0.069	2.178GluPhe: 2.178 ± 0.04	4.437GluGly: 4.437 ± 0.06	1.788GluHis: 1.788 ± 0.035	4.354GluIle: 4.354 ± 0.054	4.202GluLys: 4.202 ± 0.058	7.247GluLeu: 7.247 ± 0.087	1.995GluMet: 1.995 ± 0.041	2.607GluAsn: 2.607 ± 0.04	2.205GluPro: 2.205 ± 0.043	4.116GluGln: 4.116 ± 0.09	3.993GluArg: 3.993 ± 0.072	3.543GluSer: 3.543 ± 0.047	3.312GluThr: 3.312 ± 0.052	4.546GluVal: 4.546 ± 0.058	0.87GluTrp: 0.87 ± 0.024	2.217GluTyr: 2.217 ± 0.038	0.0GluXaa: 0.0 ± 0.0
Phe	3.039PheAla: 3.039 ± 0.037	0.381PheCys: 0.381 ± 0.016	2.2PheAsp: 2.2 ± 0.045	2.516PheGlu: 2.516 ± 0.06	1.822PhePhe: 1.822 ± 0.039	2.996PheGly: 2.996 ± 0.049	0.938PheHis: 0.938 ± 0.024	2.918PheIle: 2.918 ± 0.052	2.084PheLys: 2.084 ± 0.042	3.714PheLeu: 3.714 ± 0.066	1.2PheMet: 1.2 ± 0.031	1.704PheAsn: 1.704 ± 0.039	1.534PhePro: 1.534 ± 0.037	1.495PheGln: 1.495 ± 0.035	1.911PheArg: 1.911 ± 0.029	2.812PheSer: 2.812 ± 0.042	2.439PheThr: 2.439 ± 0.041	2.923PheVal: 2.923 ± 0.048	0.476PheTrp: 0.476 ± 0.018	1.492PheTyr: 1.492 ± 0.036	0.0PheXaa: 0.0 ± 0.0
Gly	5.164GlyAla: 5.164 ± 0.074	0.662GlyCys: 0.662 ± 0.021	3.419GlyAsp: 3.419 ± 0.052	4.449GlyGlu: 4.449 ± 0.073	3.04GlyPhe: 3.04 ± 0.052	5.097GlyGly: 5.097 ± 0.072	1.53GlyHis: 1.53 ± 0.034	5.541GlyIle: 5.541 ± 0.065	4.479GlyLys: 4.479 ± 0.058	6.833GlyLeu: 6.833 ± 0.072	2.273GlyMet: 2.273 ± 0.04	2.738GlyAsn: 2.738 ± 0.051	1.795GlyPro: 1.795 ± 0.046	2.803GlyGln: 2.803 ± 0.045	3.318GlyArg: 3.318 ± 0.051	4.559GlySer: 4.559 ± 0.063	4.395GlyThr: 4.395 ± 0.056	5.167GlyVal: 5.167 ± 0.063	0.988GlyTrp: 0.988 ± 0.025	2.896GlyTyr: 2.896 ± 0.05	0.0GlyXaa: 0.0 ± 0.0
His	1.6HisAla: 1.6 ± 0.032	0.241HisCys: 0.241 ± 0.014	1.097HisAsp: 1.097 ± 0.026	1.434HisGlu: 1.434 ± 0.029	1.083HisPhe: 1.083 ± 0.025	1.556HisGly: 1.556 ± 0.032	0.707HisHis: 0.707 ± 0.031	1.607HisIle: 1.607 ± 0.038	1.055HisLys: 1.055 ± 0.026	2.267HisLeu: 2.267 ± 0.056	0.666HisMet: 0.666 ± 0.017	0.809HisAsn: 0.809 ± 0.022	1.254HisPro: 1.254 ± 0.029	0.952HisGln: 0.952 ± 0.031	1.148HisArg: 1.148 ± 0.028	1.399HisSer: 1.399 ± 0.031	1.224HisThr: 1.224 ± 0.03	1.614HisVal: 1.614 ± 0.033	0.358HisTrp: 0.358 ± 0.014	0.863HisTyr: 0.863 ± 0.021	0.0HisXaa: 0.0 ± 0.0
Ile	5.626IleAla: 5.626 ± 0.075	0.662IleCys: 0.662 ± 0.02	3.455IleAsp: 3.455 ± 0.044	4.427IleGlu: 4.427 ± 0.065	2.51IlePhe: 2.51 ± 0.051	5.221IleGly: 5.221 ± 0.063	1.732IleHis: 1.732 ± 0.034	4.385IleIle: 4.385 ± 0.076	3.201IleLys: 3.201 ± 0.05	6.08IleLeu: 6.08 ± 0.071	1.694IleMet: 1.694 ± 0.036	2.486IleAsn: 2.486 ± 0.038	3.174IlePro: 3.174 ± 0.047	2.987IleGln: 2.987 ± 0.043	3.823IleArg: 3.823 ± 0.048	4.579IleSer: 4.579 ± 0.063	3.909IleThr: 3.909 ± 0.056	5.069IleVal: 5.069 ± 0.063	0.721IleTrp: 0.721 ± 0.021	2.188IleTyr: 2.188 ± 0.036	0.0IleXaa: 0.0 ± 0.0
Lys	4.301LysAla: 4.301 ± 0.058	0.297LysCys: 0.297 ± 0.012	3.122LysAsp: 3.122 ± 0.048	4.536LysGlu: 4.536 ± 0.058	1.55LysPhe: 1.55 ± 0.032	3.844LysGly: 3.844 ± 0.057	1.241LysHis: 1.241 ± 0.028	3.427LysIle: 3.427 ± 0.049	3.644LysLys: 3.644 ± 0.075	5.584LysLeu: 5.584 ± 0.061	1.65LysMet: 1.65 ± 0.035	2.392LysAsn: 2.392 ± 0.049	2.299LysPro: 2.299 ± 0.04	2.661LysGln: 2.661 ± 0.044	2.86LysArg: 2.86 ± 0.049	3.058LysSer: 3.058 ± 0.049	2.996LysThr: 2.996 ± 0.048	3.822LysVal: 3.822 ± 0.056	0.702LysTrp: 0.702 ± 0.022	1.895LysTyr: 1.895 ± 0.041	0.0LysXaa: 0.0 ± 0.0
Leu	7.805LeuAla: 7.805 ± 0.086	0.866LeuCys: 0.866 ± 0.025	5.301LeuAsp: 5.301 ± 0.065	6.591LeuGlu: 6.591 ± 0.079	4.41LeuPhe: 4.41 ± 0.066	6.541LeuGly: 6.541 ± 0.075	2.343LeuHis: 2.343 ± 0.044	6.49LeuIle: 6.49 ± 0.085	5.644LeuLys: 5.644 ± 0.068	10.831LeuLeu: 10.831 ± 0.116	2.623LeuMet: 2.623 ± 0.042	4.264LeuAsn: 4.264 ± 0.056	4.405LeuPro: 4.405 ± 0.063	4.058LeuGln: 4.058 ± 0.068	4.942LeuArg: 4.942 ± 0.058	7.102LeuSer: 7.102 ± 0.073	5.658LeuThr: 5.658 ± 0.062	6.216LeuVal: 6.216 ± 0.066	0.992LeuTrp: 0.992 ± 0.026	3.259LeuTyr: 3.259 ± 0.047	0.0LeuXaa: 0.0 ± 0.0
Met	2.064MetAla: 2.064 ± 0.036	0.184MetCys: 0.184 ± 0.011	1.587MetAsp: 1.587 ± 0.032	1.946MetGlu: 1.946 ± 0.033	0.999MetPhe: 0.999 ± 0.025	1.777MetGly: 1.777 ± 0.04	0.516MetHis: 0.516 ± 0.018	1.97MetIle: 1.97 ± 0.04	2.047MetLys: 2.047 ± 0.033	2.983MetLeu: 2.983 ± 0.046	0.825MetMet: 0.825 ± 0.025	1.583MetAsn: 1.583 ± 0.035	1.057MetPro: 1.057 ± 0.025	1.052MetGln: 1.052 ± 0.026	1.2MetArg: 1.2 ± 0.025	1.874MetSer: 1.874 ± 0.035	1.638MetThr: 1.638 ± 0.035	1.827MetVal: 1.827 ± 0.035	0.226MetTrp: 0.226 ± 0.011	0.83MetTyr: 0.83 ± 0.025	0.0MetXaa: 0.0 ± 0.0
Asn	2.817AsnAla: 2.817 ± 0.043	0.289AsnCys: 0.289 ± 0.015	1.945AsnAsp: 1.945 ± 0.04	2.76AsnGlu: 2.76 ± 0.046	1.383AsnPhe: 1.383 ± 0.027	3.233AsnGly: 3.233 ± 0.05	0.968AsnHis: 0.968 ± 0.028	2.656AsnIle: 2.656 ± 0.045	2.213AsnLys: 2.213 ± 0.046	3.459AsnLeu: 3.459 ± 0.052	1.136AsnMet: 1.136 ± 0.025	1.713AsnAsn: 1.713 ± 0.043	2.094AsnPro: 2.094 ± 0.035	1.681AsnGln: 1.681 ± 0.034	2.141AsnArg: 2.141 ± 0.038	2.362AsnSer: 2.362 ± 0.045	2.251AsnThr: 2.251 ± 0.044	2.812AsnVal: 2.812 ± 0.046	0.557AsnTrp: 0.557 ± 0.021	1.482AsnTyr: 1.482 ± 0.028	0.0AsnXaa: 0.0 ± 0.0
Pro	3.0ProAla: 3.0 ± 0.049	0.244ProCys: 0.244 ± 0.014	2.478ProAsp: 2.478 ± 0.041	3.262ProGlu: 3.262 ± 0.049	1.827ProPhe: 1.827 ± 0.032	2.76ProGly: 2.76 ± 0.053	0.895ProHis: 0.895 ± 0.025	2.442ProIle: 2.442 ± 0.039	1.909ProLys: 1.909 ± 0.038	3.985ProLeu: 3.985 ± 0.056	0.926ProMet: 0.926 ± 0.026	1.556ProAsn: 1.556 ± 0.029	1.163ProPro: 1.163 ± 0.029	1.568ProGln: 1.568 ± 0.031	1.347ProArg: 1.347 ± 0.033	2.54ProSer: 2.54 ± 0.044	2.017ProThr: 2.017 ± 0.037	3.285ProVal: 3.285 ± 0.051	0.476ProTrp: 0.476 ± 0.018	1.51ProTyr: 1.51 ± 0.032	0.0ProXaa: 0.0 ± 0.0
Gln	3.67GlnAla: 3.67 ± 0.061	0.233GlnCys: 0.233 ± 0.012	1.904GlnAsp: 1.904 ± 0.039	3.006GlnGlu: 3.006 ± 0.061	1.57GlnPhe: 1.57 ± 0.03	2.756GlnGly: 2.756 ± 0.043	1.023GlnHis: 1.023 ± 0.028	2.597GlnIle: 2.597 ± 0.037	2.392GlnLys: 2.392 ± 0.039	4.419GlnLeu: 4.419 ± 0.065	1.271GlnMet: 1.271 ± 0.03	1.526GlnAsn: 1.526 ± 0.03	1.63GlnPro: 1.63 ± 0.036	2.252GlnGln: 2.252 ± 0.046	2.072GlnArg: 2.072 ± 0.035	2.501GlnSer: 2.501 ± 0.043	2.267GlnThr: 2.267 ± 0.041	2.841GlnVal: 2.841 ± 0.058	0.558GlnTrp: 0.558 ± 0.019	1.518GlnTyr: 1.518 ± 0.03	0.0GlnXaa: 0.0 ± 0.0
Arg	3.069ArgAla: 3.069 ± 0.046	0.367ArgCys: 0.367 ± 0.013	2.316ArgAsp: 2.316 ± 0.04	3.733ArgGlu: 3.733 ± 0.054	2.166ArgPhe: 2.166 ± 0.04	2.815ArgGly: 2.815 ± 0.046	1.144ArgHis: 1.144 ± 0.028	3.651ArgIle: 3.651 ± 0.062	3.131ArgLys: 3.131 ± 0.046	5.261ArgLeu: 5.261 ± 0.059	1.556ArgMet: 1.556 ± 0.031	2.028ArgAsn: 2.028 ± 0.035	1.686ArgPro: 1.686 ± 0.033	2.155ArgGln: 2.155 ± 0.041	2.613ArgArg: 2.613 ± 0.043	3.058ArgSer: 3.058 ± 0.046	2.684ArgThr: 2.684 ± 0.044	3.196ArgVal: 3.196 ± 0.046	0.637ArgTrp: 0.637 ± 0.02	1.892ArgTyr: 1.892 ± 0.033	0.0ArgXaa: 0.0 ± 0.0
Ser	4.491SerAla: 4.491 ± 0.06	0.429SerCys: 0.429 ± 0.015	3.14SerAsp: 3.14 ± 0.039	3.877SerGlu: 3.877 ± 0.052	3.1SerPhe: 3.1 ± 0.049	5.106SerGly: 5.106 ± 0.07	1.371SerHis: 1.371 ± 0.031	4.415SerIle: 4.415 ± 0.066	3.476SerLys: 3.476 ± 0.053	6.417SerLeu: 6.417 ± 0.067	1.901SerMet: 1.901 ± 0.038	2.566SerAsn: 2.566 ± 0.046	2.375SerPro: 2.375 ± 0.042	2.304SerGln: 2.304 ± 0.035	3.091SerArg: 3.091 ± 0.048	4.671SerSer: 4.671 ± 0.07	3.405SerThr: 3.405 ± 0.048	4.623SerVal: 4.623 ± 0.085	0.823SerTrp: 0.823 ± 0.026	2.452SerTyr: 2.452 ± 0.042	0.0SerXaa: 0.0 ± 0.0
Thr	4.541ThrAla: 4.541 ± 0.05	0.359ThrCys: 0.359 ± 0.015	3.017ThrAsp: 3.017 ± 0.045	3.437ThrGlu: 3.437 ± 0.049	2.365ThrPhe: 2.365 ± 0.045	4.57ThrGly: 4.57 ± 0.067	1.095ThrHis: 1.095 ± 0.028	3.727ThrIle: 3.727 ± 0.051	2.674ThrLys: 2.674 ± 0.047	5.635ThrLeu: 5.635 ± 0.072	1.345ThrMet: 1.345 ± 0.028	2.077ThrAsn: 2.077 ± 0.039	2.607ThrPro: 2.607 ± 0.043	1.921ThrGln: 1.921 ± 0.042	2.304ThrArg: 2.304 ± 0.033	3.623ThrSer: 3.623 ± 0.05	3.084ThrThr: 3.084 ± 0.058	4.427ThrVal: 4.427 ± 0.081	0.642ThrTrp: 0.642 ± 0.019	1.943ThrTyr: 1.943 ± 0.033	0.0ThrXaa: 0.0 ± 0.0
Val	5.186ValAla: 5.186 ± 0.059	0.653ValCys: 0.653 ± 0.022	3.694ValAsp: 3.694 ± 0.049	4.534ValGlu: 4.534 ± 0.067	2.819ValPhe: 2.819 ± 0.049	4.475ValGly: 4.475 ± 0.067	1.58ValHis: 1.58 ± 0.035	5.031ValIle: 5.031 ± 0.07	3.876ValLys: 3.876 ± 0.057	7.338ValLeu: 7.338 ± 0.07	1.931ValMet: 1.931 ± 0.033	2.96ValAsn: 2.96 ± 0.051	2.992ValPro: 2.992 ± 0.047	2.869ValGln: 2.869 ± 0.043	3.341ValArg: 3.341 ± 0.05	4.827ValSer: 4.827 ± 0.065	4.349ValThr: 4.349 ± 0.077	4.996ValVal: 4.996 ± 0.07	0.84ValTrp: 0.84 ± 0.026	2.415ValTyr: 2.415 ± 0.041	0.0ValXaa: 0.0 ± 0.0
Trp	0.775TrpAla: 0.775 ± 0.022	0.102TrpCys: 0.102 ± 0.009	0.644TrpAsp: 0.644 ± 0.02	0.723TrpGlu: 0.723 ± 0.019	0.561TrpPhe: 0.561 ± 0.019	0.858TrpGly: 0.858 ± 0.024	0.224TrpHis: 0.224 ± 0.011	0.942TrpIle: 0.942 ± 0.024	0.763TrpLys: 0.763 ± 0.024	1.355TrpLeu: 1.355 ± 0.036	0.441TrpMet: 0.441 ± 0.018	0.69TrpAsn: 0.69 ± 0.019	0.307TrpPro: 0.307 ± 0.014	0.478TrpGln: 0.478 ± 0.019	0.579TrpArg: 0.579 ± 0.021	0.887TrpSer: 0.887 ± 0.027	0.653TrpThr: 0.653 ± 0.02	0.757TrpVal: 0.757 ± 0.023	0.172TrpTrp: 0.172 ± 0.01	0.397TrpTyr: 0.397 ± 0.017	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.499TyrAla: 2.499 ± 0.039	0.301TyrCys: 0.301 ± 0.014	1.922TyrAsp: 1.922 ± 0.041	2.316TyrGlu: 2.316 ± 0.041	1.62TyrPhe: 1.62 ± 0.032	2.629TyrGly: 2.629 ± 0.044	0.817TyrHis: 0.817 ± 0.021	2.301TyrIle: 2.301 ± 0.041	1.822TyrLys: 1.822 ± 0.035	3.257TyrLeu: 3.257 ± 0.041	0.978TyrMet: 0.978 ± 0.023	1.511TyrAsn: 1.511 ± 0.034	1.602TyrPro: 1.602 ± 0.042	1.365TyrGln: 1.365 ± 0.028	2.076TyrArg: 2.076 ± 0.042	2.205TyrSer: 2.205 ± 0.036	2.149TyrThr: 2.149 ± 0.041	2.495TyrVal: 2.495 ± 0.036	0.471TyrTrp: 0.471 ± 0.019	1.368TyrTyr: 1.368 ± 0.035	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 5377 proteins (1702113 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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