Amino acid dipepetide frequency for Changjiang picorna-like virus 1

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
6.912AlaAla: 6.912 ± 0.0
2.304AlaCys: 2.304 ± 0.0
4.608AlaAsp: 4.608 ± 0.0
2.688AlaGlu: 2.688 ± 0.0
2.688AlaPhe: 2.688 ± 0.0
5.376AlaGly: 5.376 ± 0.0
0.384AlaHis: 0.384 ± 0.0
5.376AlaIle: 5.376 ± 0.0
3.456AlaLys: 3.456 ± 0.0
6.912AlaLeu: 6.912 ± 0.0
1.536AlaMet: 1.536 ± 0.0
4.992AlaAsn: 4.992 ± 0.0
3.84AlaPro: 3.84 ± 0.0
4.224AlaGln: 4.224 ± 0.0
2.688AlaArg: 2.688 ± 0.0
4.608AlaSer: 4.608 ± 0.0
8.065AlaThr: 8.065 ± 0.0
4.992AlaVal: 4.992 ± 0.0
1.536AlaTrp: 1.536 ± 0.0
2.688AlaTyr: 2.688 ± 0.0
0.0AlaXaa: 0.0 ± 0.0
Cys
0.384CysAla: 0.384 ± 0.0
0.768CysCys: 0.768 ± 0.0
0.768CysAsp: 0.768 ± 0.0
2.304CysGlu: 2.304 ± 0.0
0.768CysPhe: 0.768 ± 0.0
0.768CysGly: 0.768 ± 0.0
0.0CysHis: 0.0 ± 0.0
0.0CysIle: 0.0 ± 0.0
0.384CysLys: 0.384 ± 0.0
0.384CysLeu: 0.384 ± 0.0
0.0CysMet: 0.0 ± 0.0
0.0CysAsn: 0.0 ± 0.0
1.152CysPro: 1.152 ± 0.0
0.0CysGln: 0.0 ± 0.0
0.768CysArg: 0.768 ± 0.0
1.536CysSer: 1.536 ± 0.0
0.768CysThr: 0.768 ± 0.0
1.152CysVal: 1.152 ± 0.0
0.384CysTrp: 0.384 ± 0.0
0.0CysTyr: 0.0 ± 0.0
0.0CysXaa: 0.0 ± 0.0
Asp
3.456AspAla: 3.456 ± 0.0
1.152AspCys: 1.152 ± 0.0
3.456AspAsp: 3.456 ± 0.0
6.144AspGlu: 6.144 ± 0.0
4.224AspPhe: 4.224 ± 0.0
1.152AspGly: 1.152 ± 0.0
0.768AspHis: 0.768 ± 0.0
2.304AspIle: 2.304 ± 0.0
3.84AspLys: 3.84 ± 0.0
3.456AspLeu: 3.456 ± 0.0
1.536AspMet: 1.536 ± 0.0
1.536AspAsn: 1.536 ± 0.0
2.304AspPro: 2.304 ± 0.0
2.688AspGln: 2.688 ± 0.0
4.608AspArg: 4.608 ± 0.0
3.456AspSer: 3.456 ± 0.0
1.536AspThr: 1.536 ± 0.0
4.608AspVal: 4.608 ± 0.0
1.152AspTrp: 1.152 ± 0.0
2.304AspTyr: 2.304 ± 0.0
0.0AspXaa: 0.0 ± 0.0
Glu
2.688GluAla: 2.688 ± 0.0
0.768GluCys: 0.768 ± 0.0
3.456GluAsp: 3.456 ± 0.0
3.84GluGlu: 3.84 ± 0.0
3.84GluPhe: 3.84 ± 0.0
2.304GluGly: 2.304 ± 0.0
1.92GluHis: 1.92 ± 0.0
1.536GluIle: 1.536 ± 0.0
3.84GluLys: 3.84 ± 0.0
5.376GluLeu: 5.376 ± 0.0
2.304GluMet: 2.304 ± 0.0
2.304GluAsn: 2.304 ± 0.0
2.688GluPro: 2.688 ± 0.0
2.688GluGln: 2.688 ± 0.0
4.224GluArg: 4.224 ± 0.0
2.304GluSer: 2.304 ± 0.0
1.536GluThr: 1.536 ± 0.0
4.224GluVal: 4.224 ± 0.0
1.536GluTrp: 1.536 ± 0.0
3.072GluTyr: 3.072 ± 0.0
0.0GluXaa: 0.0 ± 0.0
Phe
2.688PheAla: 2.688 ± 0.0
0.768PheCys: 0.768 ± 0.0
1.536PheAsp: 1.536 ± 0.0
2.304PheGlu: 2.304 ± 0.0
1.92PhePhe: 1.92 ± 0.0
3.072PheGly: 3.072 ± 0.0
0.768PheHis: 0.768 ± 0.0
3.84PheIle: 3.84 ± 0.0
1.536PheLys: 1.536 ± 0.0
5.76PheLeu: 5.76 ± 0.0
0.768PheMet: 0.768 ± 0.0
1.536PheAsn: 1.536 ± 0.0
1.536PhePro: 1.536 ± 0.0
0.768PheGln: 0.768 ± 0.0
4.608PheArg: 4.608 ± 0.0
0.768PheSer: 0.768 ± 0.0
5.376PheThr: 5.376 ± 0.0
3.84PheVal: 3.84 ± 0.0
0.768PheTrp: 0.768 ± 0.0
3.072PheTyr: 3.072 ± 0.0
0.0PheXaa: 0.0 ± 0.0
Gly
3.84GlyAla: 3.84 ± 0.0
0.0GlyCys: 0.0 ± 0.0
5.376GlyAsp: 5.376 ± 0.0
3.072GlyGlu: 3.072 ± 0.0
3.84GlyPhe: 3.84 ± 0.0
3.84GlyGly: 3.84 ± 0.0
1.92GlyHis: 1.92 ± 0.0
4.224GlyIle: 4.224 ± 0.0
2.304GlyLys: 2.304 ± 0.0
3.072GlyLeu: 3.072 ± 0.0
1.152GlyMet: 1.152 ± 0.0
1.92GlyAsn: 1.92 ± 0.0
3.84GlyPro: 3.84 ± 0.0
0.384GlyGln: 0.384 ± 0.0
4.992GlyArg: 4.992 ± 0.0
3.456GlySer: 3.456 ± 0.0
3.84GlyThr: 3.84 ± 0.0
6.144GlyVal: 6.144 ± 0.0
1.92GlyTrp: 1.92 ± 0.0
1.92GlyTyr: 1.92 ± 0.0
0.0GlyXaa: 0.0 ± 0.0
His
2.304HisAla: 2.304 ± 0.0
0.384HisCys: 0.384 ± 0.0
0.0HisAsp: 0.0 ± 0.0
0.768HisGlu: 0.768 ± 0.0
0.384HisPhe: 0.384 ± 0.0
1.536HisGly: 1.536 ± 0.0
0.0HisHis: 0.0 ± 0.0
1.92HisIle: 1.92 ± 0.0
0.768HisLys: 0.768 ± 0.0
1.152HisLeu: 1.152 ± 0.0
1.152HisMet: 1.152 ± 0.0
0.384HisAsn: 0.384 ± 0.0
1.536HisPro: 1.536 ± 0.0
2.304HisGln: 2.304 ± 0.0
1.92HisArg: 1.92 ± 0.0
1.536HisSer: 1.536 ± 0.0
2.304HisThr: 2.304 ± 0.0
1.152HisVal: 1.152 ± 0.0
0.0HisTrp: 0.0 ± 0.0
0.384HisTyr: 0.384 ± 0.0
0.0HisXaa: 0.0 ± 0.0
Ile
4.224IleAla: 4.224 ± 0.0
0.384IleCys: 0.384 ± 0.0
4.224IleAsp: 4.224 ± 0.0
3.072IleGlu: 3.072 ± 0.0
1.152IlePhe: 1.152 ± 0.0
1.152IleGly: 1.152 ± 0.0
1.152IleHis: 1.152 ± 0.0
2.688IleIle: 2.688 ± 0.0
1.536IleLys: 1.536 ± 0.0
3.84IleLeu: 3.84 ± 0.0
1.536IleMet: 1.536 ± 0.0
3.072IleAsn: 3.072 ± 0.0
4.992IlePro: 4.992 ± 0.0
2.688IleGln: 2.688 ± 0.0
3.456IleArg: 3.456 ± 0.0
3.84IleSer: 3.84 ± 0.0
3.072IleThr: 3.072 ± 0.0
3.84IleVal: 3.84 ± 0.0
0.384IleTrp: 0.384 ± 0.0
2.304IleTyr: 2.304 ± 0.0
0.0IleXaa: 0.0 ± 0.0
Lys
4.608LysAla: 4.608 ± 0.0
0.768LysCys: 0.768 ± 0.0
1.536LysAsp: 1.536 ± 0.0
2.304LysGlu: 2.304 ± 0.0
1.92LysPhe: 1.92 ± 0.0
2.304LysGly: 2.304 ± 0.0
1.92LysHis: 1.92 ± 0.0
2.688LysIle: 2.688 ± 0.0
2.304LysLys: 2.304 ± 0.0
3.84LysLeu: 3.84 ± 0.0
2.688LysMet: 2.688 ± 0.0
1.92LysAsn: 1.92 ± 0.0
2.304LysPro: 2.304 ± 0.0
0.768LysGln: 0.768 ± 0.0
4.992LysArg: 4.992 ± 0.0
2.688LysSer: 2.688 ± 0.0
0.768LysThr: 0.768 ± 0.0
2.304LysVal: 2.304 ± 0.0
0.0LysTrp: 0.0 ± 0.0
0.768LysTyr: 0.768 ± 0.0
0.0LysXaa: 0.0 ± 0.0
Leu
5.76LeuAla: 5.76 ± 0.0
1.536LeuCys: 1.536 ± 0.0
4.224LeuAsp: 4.224 ± 0.0
3.072LeuGlu: 3.072 ± 0.0
4.224LeuPhe: 4.224 ± 0.0
5.76LeuGly: 5.76 ± 0.0
1.536LeuHis: 1.536 ± 0.0
2.688LeuIle: 2.688 ± 0.0
4.608LeuLys: 4.608 ± 0.0
6.528LeuLeu: 6.528 ± 0.0
1.152LeuMet: 1.152 ± 0.0
2.304LeuAsn: 2.304 ± 0.0
3.072LeuPro: 3.072 ± 0.0
1.536LeuGln: 1.536 ± 0.0
4.224LeuArg: 4.224 ± 0.0
9.217LeuSer: 9.217 ± 0.0
4.992LeuThr: 4.992 ± 0.0
4.992LeuVal: 4.992 ± 0.0
0.384LeuTrp: 0.384 ± 0.0
4.224LeuTyr: 4.224 ± 0.0
0.0LeuXaa: 0.0 ± 0.0
Met
2.304MetAla: 2.304 ± 0.0
0.384MetCys: 0.384 ± 0.0
1.536MetAsp: 1.536 ± 0.0
1.152MetGlu: 1.152 ± 0.0
1.152MetPhe: 1.152 ± 0.0
3.84MetGly: 3.84 ± 0.0
0.768MetHis: 0.768 ± 0.0
1.92MetIle: 1.92 ± 0.0
0.768MetLys: 0.768 ± 0.0
2.304MetLeu: 2.304 ± 0.0
0.0MetMet: 0.0 ± 0.0
1.92MetAsn: 1.92 ± 0.0
1.152MetPro: 1.152 ± 0.0
0.384MetGln: 0.384 ± 0.0
1.536MetArg: 1.536 ± 0.0
2.304MetSer: 2.304 ± 0.0
1.536MetThr: 1.536 ± 0.0
4.608MetVal: 4.608 ± 0.0
0.0MetTrp: 0.0 ± 0.0
0.384MetTyr: 0.384 ± 0.0
0.0MetXaa: 0.0 ± 0.0
Asn
3.456AsnAla: 3.456 ± 0.0
0.0AsnCys: 0.0 ± 0.0
0.384AsnAsp: 0.384 ± 0.0
1.536AsnGlu: 1.536 ± 0.0
1.92AsnPhe: 1.92 ± 0.0
3.072AsnGly: 3.072 ± 0.0
1.152AsnHis: 1.152 ± 0.0
3.072AsnIle: 3.072 ± 0.0
1.152AsnLys: 1.152 ± 0.0
2.688AsnLeu: 2.688 ± 0.0
1.92AsnMet: 1.92 ± 0.0
2.688AsnAsn: 2.688 ± 0.0
1.536AsnPro: 1.536 ± 0.0
1.536AsnGln: 1.536 ± 0.0
0.384AsnArg: 0.384 ± 0.0
3.456AsnSer: 3.456 ± 0.0
4.992AsnThr: 4.992 ± 0.0
4.224AsnVal: 4.224 ± 0.0
0.768AsnTrp: 0.768 ± 0.0
0.384AsnTyr: 0.384 ± 0.0
0.0AsnXaa: 0.0 ± 0.0
Pro
3.072ProAla: 3.072 ± 0.0
0.0ProCys: 0.0 ± 0.0
2.304ProAsp: 2.304 ± 0.0
4.992ProGlu: 4.992 ± 0.0
2.688ProPhe: 2.688 ± 0.0
3.84ProGly: 3.84 ± 0.0
1.92ProHis: 1.92 ± 0.0
2.304ProIle: 2.304 ± 0.0
3.072ProLys: 3.072 ± 0.0
2.688ProLeu: 2.688 ± 0.0
2.688ProMet: 2.688 ± 0.0
0.768ProAsn: 0.768 ± 0.0
0.768ProPro: 0.768 ± 0.0
2.304ProGln: 2.304 ± 0.0
1.536ProArg: 1.536 ± 0.0
4.608ProSer: 4.608 ± 0.0
3.84ProThr: 3.84 ± 0.0
4.992ProVal: 4.992 ± 0.0
0.768ProTrp: 0.768 ± 0.0
4.608ProTyr: 4.608 ± 0.0
0.0ProXaa: 0.0 ± 0.0
Gln
2.304GlnAla: 2.304 ± 0.0
0.768GlnCys: 0.768 ± 0.0
2.304GlnAsp: 2.304 ± 0.0
1.92GlnGlu: 1.92 ± 0.0
0.768GlnPhe: 0.768 ± 0.0
1.536GlnGly: 1.536 ± 0.0
0.768GlnHis: 0.768 ± 0.0
1.536GlnIle: 1.536 ± 0.0
1.92GlnLys: 1.92 ± 0.0
1.92GlnLeu: 1.92 ± 0.0
0.0GlnMet: 0.0 ± 0.0
1.536GlnAsn: 1.536 ± 0.0
2.304GlnPro: 2.304 ± 0.0
2.304GlnGln: 2.304 ± 0.0
1.152GlnArg: 1.152 ± 0.0
3.84GlnSer: 3.84 ± 0.0
2.304GlnThr: 2.304 ± 0.0
1.92GlnVal: 1.92 ± 0.0
0.768GlnTrp: 0.768 ± 0.0
1.152GlnTyr: 1.152 ± 0.0
0.0GlnXaa: 0.0 ± 0.0
Arg
3.072ArgAla: 3.072 ± 0.0
0.384ArgCys: 0.384 ± 0.0
4.224ArgAsp: 4.224 ± 0.0
4.224ArgGlu: 4.224 ± 0.0
1.92ArgPhe: 1.92 ± 0.0
4.992ArgGly: 4.992 ± 0.0
0.768ArgHis: 0.768 ± 0.0
3.072ArgIle: 3.072 ± 0.0
1.152ArgLys: 1.152 ± 0.0
4.992ArgLeu: 4.992 ± 0.0
2.304ArgMet: 2.304 ± 0.0
1.92ArgAsn: 1.92 ± 0.0
3.072ArgPro: 3.072 ± 0.0
1.536ArgGln: 1.536 ± 0.0
4.608ArgArg: 4.608 ± 0.0
5.76ArgSer: 5.76 ± 0.0
1.92ArgThr: 1.92 ± 0.0
3.456ArgVal: 3.456 ± 0.0
0.768ArgTrp: 0.768 ± 0.0
1.92ArgTyr: 1.92 ± 0.0
0.0ArgXaa: 0.0 ± 0.0
Ser
7.68SerAla: 7.68 ± 0.0
0.0SerCys: 0.0 ± 0.0
3.456SerAsp: 3.456 ± 0.0
4.224SerGlu: 4.224 ± 0.0
2.304SerPhe: 2.304 ± 0.0
4.992SerGly: 4.992 ± 0.0
0.384SerHis: 0.384 ± 0.0
7.68SerIle: 7.68 ± 0.0
4.992SerLys: 4.992 ± 0.0
8.065SerLeu: 8.065 ± 0.0
1.536SerMet: 1.536 ± 0.0
2.304SerAsn: 2.304 ± 0.0
4.224SerPro: 4.224 ± 0.0
1.92SerGln: 1.92 ± 0.0
1.152SerArg: 1.152 ± 0.0
8.449SerSer: 8.449 ± 0.0
6.144SerThr: 6.144 ± 0.0
3.84SerVal: 3.84 ± 0.0
0.384SerTrp: 0.384 ± 0.0
3.456SerTyr: 3.456 ± 0.0
0.0SerXaa: 0.0 ± 0.0
Thr
7.296ThrAla: 7.296 ± 0.0
0.0ThrCys: 0.0 ± 0.0
3.456ThrAsp: 3.456 ± 0.0
2.688ThrGlu: 2.688 ± 0.0
4.224ThrPhe: 4.224 ± 0.0
4.608ThrGly: 4.608 ± 0.0
2.304ThrHis: 2.304 ± 0.0
2.304ThrIle: 2.304 ± 0.0
2.688ThrLys: 2.688 ± 0.0
3.84ThrLeu: 3.84 ± 0.0
2.304ThrMet: 2.304 ± 0.0
3.072ThrAsn: 3.072 ± 0.0
4.992ThrPro: 4.992 ± 0.0
1.152ThrGln: 1.152 ± 0.0
2.688ThrArg: 2.688 ± 0.0
4.608ThrSer: 4.608 ± 0.0
8.833ThrThr: 8.833 ± 0.0
6.528ThrVal: 6.528 ± 0.0
0.768ThrTrp: 0.768 ± 0.0
2.688ThrTyr: 2.688 ± 0.0
0.0ThrXaa: 0.0 ± 0.0
Val
9.601ValAla: 9.601 ± 0.0
0.768ValCys: 0.768 ± 0.0
4.224ValAsp: 4.224 ± 0.0
3.456ValGlu: 3.456 ± 0.0
4.992ValPhe: 4.992 ± 0.0
3.84ValGly: 3.84 ± 0.0
1.152ValHis: 1.152 ± 0.0
2.304ValIle: 2.304 ± 0.0
1.536ValLys: 1.536 ± 0.0
5.376ValLeu: 5.376 ± 0.0
2.688ValMet: 2.688 ± 0.0
2.688ValAsn: 2.688 ± 0.0
5.376ValPro: 5.376 ± 0.0
1.536ValGln: 1.536 ± 0.0
1.92ValArg: 1.92 ± 0.0
7.296ValSer: 7.296 ± 0.0
6.144ValThr: 6.144 ± 0.0
3.456ValVal: 3.456 ± 0.0
1.92ValTrp: 1.92 ± 0.0
4.608ValTyr: 4.608 ± 0.0
0.0ValXaa: 0.0 ± 0.0
Trp
1.152TrpAla: 1.152 ± 0.0
0.384TrpCys: 0.384 ± 0.0
2.304TrpAsp: 2.304 ± 0.0
1.152TrpGlu: 1.152 ± 0.0
1.152TrpPhe: 1.152 ± 0.0
0.0TrpGly: 0.0 ± 0.0
0.384TrpHis: 0.384 ± 0.0
0.384TrpIle: 0.384 ± 0.0
0.384TrpLys: 0.384 ± 0.0
0.768TrpLeu: 0.768 ± 0.0
0.384TrpMet: 0.384 ± 0.0
1.92TrpAsn: 1.92 ± 0.0
0.0TrpPro: 0.0 ± 0.0
0.384TrpGln: 0.384 ± 0.0
1.152TrpArg: 1.152 ± 0.0
0.768TrpSer: 0.768 ± 0.0
0.384TrpThr: 0.384 ± 0.0
1.152TrpVal: 1.152 ± 0.0
0.384TrpTrp: 0.384 ± 0.0
0.384TrpTyr: 0.384 ± 0.0
0.0TrpXaa: 0.0 ± 0.0
Tyr
3.072TyrAla: 3.072 ± 0.0
0.768TyrCys: 0.768 ± 0.0
2.304TyrAsp: 2.304 ± 0.0
1.536TyrGlu: 1.536 ± 0.0
1.152TyrPhe: 1.152 ± 0.0
3.072TyrGly: 3.072 ± 0.0
1.92TyrHis: 1.92 ± 0.0
0.768TyrIle: 0.768 ± 0.0
1.152TyrLys: 1.152 ± 0.0
3.456TyrLeu: 3.456 ± 0.0
1.92TyrMet: 1.92 ± 0.0
1.536TyrAsn: 1.536 ± 0.0
3.072TyrPro: 3.072 ± 0.0
1.92TyrGln: 1.92 ± 0.0
3.456TyrArg: 3.456 ± 0.0
2.688TyrSer: 2.688 ± 0.0
2.688TyrThr: 2.688 ± 0.0
3.456TyrVal: 3.456 ± 0.0
0.384TyrTrp: 0.384 ± 0.0
1.92TyrTyr: 1.92 ± 0.0
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 1 proteins (2605 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski