Molluscum contagiosum virus subtype 1 (MOCV) (MCVI)

Taxonomy: Viruses; Varidnaviria; Bamfordvirae; Nucleocytoviricota; Pokkesviricetes; Chitovirales; Poxviridae; Chordopoxvirinae; Molluscipoxvirus; Molluscum contagiosum virus

Average proteome isoelectric point is 7.35

Get precalculated fractions of proteins

Acidic
pI < 6.8
6.8-7.4
pI > 7.4
Basic
    
All



Virtual 2D-PAGE plot for 163 proteins (isoelectric point calculated using IPC2_protein)

Get csv file with sequences according to given criteria:
        -     Method 

     -  kDa    
                                                                                      

* You can choose from 21 different methods for calculating isoelectric point

Summary statistics related to proteome-wise predictions


    
Protein with the lowest isoelectric point:
>tr|Q98183|Q98183_MCV1 MC012 OS=Molluscum contagiosum virus subtype 1 OX=10280 GN=MC012L PE=4 SV=1
MM1 pKa = 5.97QTCSARR7 pKa = 11.84RR8 pKa = 11.84RR9 pKa = 11.84PRR11 pKa = 11.84AAAALVVACAGALMALCAVMVSCAGDD37 pKa = 3.36VFVEE41 pKa = 4.21VSTNEE46 pKa = 3.95THH48 pKa = 7.43SLGLGSPLDD57 pKa = 4.02GDD59 pKa = 3.87GFPYY63 pKa = 10.89EE64 pKa = 4.38NFTLVLWNCTSNDD77 pKa = 3.44TAPPCGEE84 pKa = 4.91IWDD87 pKa = 3.8LWNRR91 pKa = 11.84TFPLMTLTNGTSGPEE106 pKa = 4.08VTVSGYY112 pKa = 7.54FTNQNGTCHH121 pKa = 6.44PGKK124 pKa = 10.78YY125 pKa = 9.48FGEE128 pKa = 4.49VMGSSGTSPNTLGLRR143 pKa = 11.84GLCQYY148 pKa = 10.74GNSSEE153 pKa = 4.02RR154 pKa = 11.84FPWFKK159 pKa = 10.28FVYY162 pKa = 10.49YY163 pKa = 10.55DD164 pKa = 4.57GNDD167 pKa = 3.7GNDD170 pKa = 3.46GDD172 pKa = 4.81DD173 pKa = 3.34THH175 pKa = 7.39EE176 pKa = 5.48DD177 pKa = 3.05GGEE180 pKa = 4.1YY181 pKa = 10.44YY182 pKa = 10.81DD183 pKa = 5.68GDD185 pKa = 4.23DD186 pKa = 5.19GGDD189 pKa = 3.49GGNGGNGGDD198 pKa = 4.34GGDD201 pKa = 4.4GGDD204 pKa = 5.82DD205 pKa = 4.84GDD207 pKa = 6.37DD208 pKa = 5.15DD209 pKa = 6.98DD210 pKa = 7.63DD211 pKa = 7.39DD212 pKa = 7.16DD213 pKa = 7.36GDD215 pKa = 4.5DD216 pKa = 4.02GKK218 pKa = 10.11CTFTVYY224 pKa = 11.21NLTAEE229 pKa = 4.31SLTDD233 pKa = 3.22YY234 pKa = 11.51SPIHH238 pKa = 6.29WPANTTMPPEE248 pKa = 4.01LQVRR252 pKa = 11.84LNQTGGDD259 pKa = 3.55DD260 pKa = 3.87VLNVTVPPGLFDD272 pKa = 4.86EE273 pKa = 4.71MALANATHH281 pKa = 5.42QWIGLVVNMTHH292 pKa = 6.89LCSMVV297 pKa = 2.77

Molecular weight: 31.5 kDa
Isoelectric point according different methods:





Protein with the highest isoelectric point:
>tr|Q98291|Q98291_MCV1 MC124 OS=Molluscum contagiosum virus subtype 1 OX=10280 GN=MC124L PE=3 SV=1
MM1 pKa = 7.52SGFLAMDD8 pKa = 4.27DD9 pKa = 4.81KK10 pKa = 11.63LYY12 pKa = 10.84TDD14 pKa = 4.18LKK16 pKa = 10.3KK17 pKa = 10.89LVGAQPLYY25 pKa = 11.05LFTARR30 pKa = 11.84GDD32 pKa = 3.79FVEE35 pKa = 4.28VARR38 pKa = 11.84RR39 pKa = 11.84SEE41 pKa = 3.69FRR43 pKa = 11.84FRR45 pKa = 11.84VPAGFFAGEE54 pKa = 4.25GVALRR59 pKa = 11.84GQQFPAGSARR69 pKa = 11.84MPDD72 pKa = 3.49AAHH75 pKa = 6.56LRR77 pKa = 11.84LPRR80 pKa = 11.84LYY82 pKa = 9.75PAQQQVVAEE91 pKa = 4.2LRR93 pKa = 11.84AIAKK97 pKa = 9.8ACARR101 pKa = 11.84EE102 pKa = 3.88QRR104 pKa = 11.84PLYY107 pKa = 8.95VTLHH111 pKa = 6.28LACGFGKK118 pKa = 8.59TVTASYY124 pKa = 11.43LLGTHH129 pKa = 6.23RR130 pKa = 11.84RR131 pKa = 11.84RR132 pKa = 11.84AVVCVPTKK140 pKa = 10.3MLLAQWGAVLAALRR154 pKa = 11.84VSVYY158 pKa = 10.4VSGEE162 pKa = 4.04GVRR165 pKa = 11.84KK166 pKa = 9.98LMSVLRR172 pKa = 11.84TRR174 pKa = 11.84DD175 pKa = 3.4FSVLVVVNKK184 pKa = 10.17HH185 pKa = 5.09FADD188 pKa = 4.1PGFCALVHH196 pKa = 5.7EE197 pKa = 5.22RR198 pKa = 11.84YY199 pKa = 10.11DD200 pKa = 3.58VFVLDD205 pKa = 4.81EE206 pKa = 4.2SHH208 pKa = 6.98TYY210 pKa = 11.44NLMNLTLMTRR220 pKa = 11.84FLSFFPPRR228 pKa = 11.84ICYY231 pKa = 9.22FLSATPRR238 pKa = 11.84AANRR242 pKa = 11.84VYY244 pKa = 10.63CNRR247 pKa = 11.84VVNVTKK253 pKa = 10.38FSALRR258 pKa = 11.84KK259 pKa = 6.36TVRR262 pKa = 11.84VLSTFFPPFSNARR275 pKa = 11.84IRR277 pKa = 11.84EE278 pKa = 3.98FVQRR282 pKa = 11.84LDD284 pKa = 3.71SVHH287 pKa = 6.1NKK289 pKa = 7.37YY290 pKa = 10.49HH291 pKa = 6.98IYY293 pKa = 9.32TEE295 pKa = 4.02KK296 pKa = 11.01ALAEE300 pKa = 4.2DD301 pKa = 4.05APRR304 pKa = 11.84NASIVAVTAAAFEE317 pKa = 4.3HH318 pKa = 6.96RR319 pKa = 11.84DD320 pKa = 3.11AHH322 pKa = 6.24RR323 pKa = 11.84VLLITKK329 pKa = 9.37LRR331 pKa = 11.84SHH333 pKa = 6.59MLGMHH338 pKa = 7.0AALSARR344 pKa = 11.84LGAQHH349 pKa = 6.56VFLGDD354 pKa = 3.22AQSRR358 pKa = 11.84HH359 pKa = 4.85TPEE362 pKa = 3.8IVCEE366 pKa = 4.04LRR368 pKa = 11.84ASEE371 pKa = 4.28RR372 pKa = 11.84FVFVSTLFYY381 pKa = 10.98SGTGLDD387 pKa = 3.82IPHH390 pKa = 7.8LDD392 pKa = 3.53TLVVCHH398 pKa = 6.46AVMNHH403 pKa = 4.81MQAEE407 pKa = 4.16QLLGRR412 pKa = 11.84ICRR415 pKa = 11.84EE416 pKa = 3.73TEE418 pKa = 3.67QPRR421 pKa = 11.84RR422 pKa = 11.84TVYY425 pKa = 10.06VFPTTSVRR433 pKa = 11.84EE434 pKa = 4.12IKK436 pKa = 11.14NMVGLFAQRR445 pKa = 11.84FITLATQKK453 pKa = 10.93LGFTQEE459 pKa = 3.93RR460 pKa = 11.84EE461 pKa = 4.18QPEE464 pKa = 4.35DD465 pKa = 3.29AAVPASADD473 pKa = 3.71RR474 pKa = 11.84PASADD479 pKa = 2.88KK480 pKa = 10.48RR481 pKa = 11.84APADD485 pKa = 3.73RR486 pKa = 11.84PAPADD491 pKa = 3.89RR492 pKa = 11.84PASADD497 pKa = 2.88KK498 pKa = 10.48RR499 pKa = 11.84APADD503 pKa = 3.91RR504 pKa = 11.84PASADD509 pKa = 2.88KK510 pKa = 10.48RR511 pKa = 11.84APADD515 pKa = 3.91RR516 pKa = 11.84PASADD521 pKa = 2.88KK522 pKa = 10.48RR523 pKa = 11.84APADD527 pKa = 3.91RR528 pKa = 11.84PASADD533 pKa = 2.88KK534 pKa = 10.48RR535 pKa = 11.84APADD539 pKa = 3.83RR540 pKa = 11.84PASADD545 pKa = 3.84RR546 pKa = 11.84TAHH549 pKa = 6.39AYY551 pKa = 7.93WRR553 pKa = 11.84ANGPCCSNRR562 pKa = 11.84FASADD567 pKa = 3.44NKK569 pKa = 10.58KK570 pKa = 9.56PALSISRR577 pKa = 11.84ASGGDD582 pKa = 3.29NAVEE586 pKa = 4.53LGHH589 pKa = 6.79KK590 pKa = 9.23PGPGPGTHH598 pKa = 6.84ASLRR602 pKa = 11.84SVRR605 pKa = 11.84KK606 pKa = 9.23HH607 pKa = 5.29GRR609 pKa = 11.84SLACEE614 pKa = 4.32LAQGTQCRR622 pKa = 11.84SARR625 pKa = 11.84RR626 pKa = 11.84AVQRR630 pKa = 11.84VGPGRR635 pKa = 11.84GHH637 pKa = 6.41AQRR640 pKa = 11.84AGLQLAHH647 pKa = 7.24IGEE650 pKa = 4.37EE651 pKa = 4.47CEE653 pKa = 4.04ARR655 pKa = 11.84LAHH658 pKa = 6.65GARR661 pKa = 11.84GARR664 pKa = 11.84VRR666 pKa = 11.84GRR668 pKa = 11.84LLHH671 pKa = 6.29GGTRR675 pKa = 11.84LALAPPLLGSGHH687 pKa = 5.13VHH689 pKa = 7.34LDD691 pKa = 3.23AEE693 pKa = 4.67KK694 pKa = 10.81

Molecular weight: 76.18 kDa
Isoelectric point according different methods:





Peptides (in silico digests for buttom-up proteomics)

Below you can find in silico digests of the whole proteome with Trypsin, Chymotrypsin, Trypsin+LysC, LysN, ArgC proteases suitable for different mass spec machines.

Try
ESI
ChTry
ESI
ArgC
ESI
LysN
ESI
TryLysC
ESI

Try
MALDI
ChTry
MALDI
ArgC
MALDI
LysN
MALDI
TryLysC
MALDI

Try
LTQ
ChTry
LTQ
ArgC
LTQ
LysN
LTQ
TryLysC
LTQ

Try
MSlow
ChTry
MSlow
ArgC
MSlow
LysN
MSlow
TryLysC
MSlow

Try
MShigh
ChTry
MShigh
ArgC
MShigh
LysN
MShigh
TryLysC
MShigh

General Statistics

Number of major isoforms

Number of additional isoforms

Number of all proteins

Number of amino acids

Min. Seq. Length

Max. Seq. Length

Avg. Seq. Length

Avg. Mol. Weight

163

0

163

54465

53

2133

334.1

37.18

Amino acid frequency

Ala

Cys

Asp

Glu

Phe

Gly

His

Ile

Lys

Leu

10.818 ± 0.376

2.701 ± 0.14

4.785 ± 0.124

5.956 ± 0.143

4.17 ± 0.195

5.587 ± 0.195

2.745 ± 0.097

3.072 ± 0.23

2.998 ± 0.192

11.079 ± 0.206

Met

Asn

Gln

Pro

Arg

Ser

Thr

Val

Trp

Tyr

2.187 ± 0.076

2.987 ± 0.162

5.473 ± 0.194

3.028 ± 0.165

8.815 ± 0.236

6.942 ± 0.186

4.966 ± 0.167

7.73 ± 0.154

0.736 ± 0.048

3.226 ± 0.112
Note: For amino acid frequency statistics the error has been estimated with the bootstraping (x100) at the protein level

Most of the basic statistics you can see at this page can be downloaded from this CSV file

For dipeptide frequency statistics click here
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski