Amino acid dipepetide frequency for Pseudomonas phage D3112 (Bacteriophage D3112)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
17.697AlaAla: 17.697 ± 1.755
1.185AlaCys: 1.185 ± 0.353
7.197AlaAsp: 7.197 ± 0.654
8.637AlaGlu: 8.637 ± 1.149
3.302AlaPhe: 3.302 ± 0.402
9.653AlaGly: 9.653 ± 0.953
1.439AlaHis: 1.439 ± 0.315
5.758AlaIle: 5.758 ± 0.701
4.742AlaLys: 4.742 ± 0.718
12.193AlaLeu: 12.193 ± 1.121
3.81AlaMet: 3.81 ± 0.495
3.641AlaAsn: 3.641 ± 0.595
5.08AlaPro: 5.08 ± 0.537
6.097AlaGln: 6.097 ± 0.785
9.399AlaArg: 9.399 ± 1.044
7.367AlaSer: 7.367 ± 0.897
6.774AlaThr: 6.774 ± 0.721
7.197AlaVal: 7.197 ± 0.756
2.032AlaTrp: 2.032 ± 0.329
2.71AlaTyr: 2.71 ± 0.458
0.0AlaXaa: 0.0 ± 0.0
Cys
0.762CysAla: 0.762 ± 0.279
0.0CysCys: 0.0 ± 0.0
1.016CysAsp: 1.016 ± 0.267
0.677CysGlu: 0.677 ± 0.328
0.593CysPhe: 0.593 ± 0.212
0.593CysGly: 0.593 ± 0.189
0.423CysHis: 0.423 ± 0.19
0.254CysIle: 0.254 ± 0.136
0.085CysLys: 0.085 ± 0.092
0.423CysLeu: 0.423 ± 0.175
0.254CysMet: 0.254 ± 0.13
0.254CysAsn: 0.254 ± 0.151
0.593CysPro: 0.593 ± 0.234
0.085CysGln: 0.085 ± 0.086
0.762CysArg: 0.762 ± 0.33
0.593CysSer: 0.593 ± 0.208
0.339CysThr: 0.339 ± 0.19
0.339CysVal: 0.339 ± 0.168
0.339CysTrp: 0.339 ± 0.154
0.169CysTyr: 0.169 ± 0.106
0.0CysXaa: 0.0 ± 0.0
Asp
5.927AspAla: 5.927 ± 0.677
0.254AspCys: 0.254 ± 0.148
3.726AspAsp: 3.726 ± 0.605
3.895AspGlu: 3.895 ± 0.671
1.693AspPhe: 1.693 ± 0.363
6.097AspGly: 6.097 ± 0.713
1.355AspHis: 1.355 ± 0.311
2.117AspIle: 2.117 ± 0.321
1.27AspLys: 1.27 ± 0.339
5.25AspLeu: 5.25 ± 0.673
1.609AspMet: 1.609 ± 0.445
1.778AspAsn: 1.778 ± 0.362
2.964AspPro: 2.964 ± 0.467
3.81AspGln: 3.81 ± 0.684
3.387AspArg: 3.387 ± 0.479
3.387AspSer: 3.387 ± 0.434
3.218AspThr: 3.218 ± 0.483
4.234AspVal: 4.234 ± 0.614
1.355AspTrp: 1.355 ± 0.277
1.524AspTyr: 1.524 ± 0.368
0.0AspXaa: 0.0 ± 0.0
Glu
7.451GluAla: 7.451 ± 0.779
0.593GluCys: 0.593 ± 0.269
2.794GluAsp: 2.794 ± 0.492
3.218GluGlu: 3.218 ± 0.551
2.286GluPhe: 2.286 ± 0.534
3.726GluGly: 3.726 ± 0.45
0.931GluHis: 0.931 ± 0.249
2.794GluIle: 2.794 ± 0.517
2.371GluLys: 2.371 ± 0.383
6.605GluLeu: 6.605 ± 0.603
1.524GluMet: 1.524 ± 0.395
1.27GluAsn: 1.27 ± 0.436
3.048GluPro: 3.048 ± 0.537
3.472GluGln: 3.472 ± 0.525
4.826GluArg: 4.826 ± 0.698
2.54GluSer: 2.54 ± 0.43
2.964GluThr: 2.964 ± 0.481
4.234GluVal: 4.234 ± 0.571
1.016GluTrp: 1.016 ± 0.237
1.439GluTyr: 1.439 ± 0.335
0.0GluXaa: 0.0 ± 0.0
Phe
3.472PheAla: 3.472 ± 0.474
0.339PheCys: 0.339 ± 0.163
2.286PheAsp: 2.286 ± 0.419
1.27PheGlu: 1.27 ± 0.332
0.762PhePhe: 0.762 ± 0.215
2.794PheGly: 2.794 ± 0.564
0.339PheHis: 0.339 ± 0.151
1.185PheIle: 1.185 ± 0.3
1.016PheLys: 1.016 ± 0.258
2.202PheLeu: 2.202 ± 0.412
0.847PheMet: 0.847 ± 0.266
1.101PheAsn: 1.101 ± 0.313
1.355PhePro: 1.355 ± 0.366
1.439PheGln: 1.439 ± 0.329
1.948PheArg: 1.948 ± 0.448
1.101PheSer: 1.101 ± 0.316
1.609PheThr: 1.609 ± 0.328
1.355PheVal: 1.355 ± 0.28
0.254PheTrp: 0.254 ± 0.143
1.016PheTyr: 1.016 ± 0.271
0.0PheXaa: 0.0 ± 0.0
Gly
7.113GlyAla: 7.113 ± 0.982
0.593GlyCys: 0.593 ± 0.197
4.572GlyAsp: 4.572 ± 0.736
4.657GlyGlu: 4.657 ± 0.509
2.964GlyPhe: 2.964 ± 0.401
6.943GlyGly: 6.943 ± 0.763
0.847GlyHis: 0.847 ± 0.254
3.556GlyIle: 3.556 ± 0.566
2.71GlyLys: 2.71 ± 0.461
7.028GlyLeu: 7.028 ± 0.863
1.524GlyMet: 1.524 ± 0.468
2.202GlyAsn: 2.202 ± 0.397
2.54GlyPro: 2.54 ± 0.334
4.826GlyGln: 4.826 ± 0.621
7.113GlyArg: 7.113 ± 0.704
5.08GlySer: 5.08 ± 0.633
4.572GlyThr: 4.572 ± 0.484
5.504GlyVal: 5.504 ± 0.639
1.948GlyTrp: 1.948 ± 0.41
2.54GlyTyr: 2.54 ± 0.68
0.0GlyXaa: 0.0 ± 0.0
His
1.778HisAla: 1.778 ± 0.274
0.085HisCys: 0.085 ± 0.083
0.931HisAsp: 0.931 ± 0.245
0.762HisGlu: 0.762 ± 0.273
0.423HisPhe: 0.423 ± 0.193
0.931HisGly: 0.931 ± 0.238
0.085HisHis: 0.085 ± 0.079
0.593HisIle: 0.593 ± 0.212
0.339HisLys: 0.339 ± 0.174
1.524HisLeu: 1.524 ± 0.355
0.847HisMet: 0.847 ± 0.29
0.677HisAsn: 0.677 ± 0.262
1.693HisPro: 1.693 ± 0.376
0.931HisGln: 0.931 ± 0.287
1.016HisArg: 1.016 ± 0.304
0.593HisSer: 0.593 ± 0.236
0.847HisThr: 0.847 ± 0.242
0.508HisVal: 0.508 ± 0.171
0.339HisTrp: 0.339 ± 0.132
1.016HisTyr: 1.016 ± 0.259
0.0HisXaa: 0.0 ± 0.0
Ile
6.181IleAla: 6.181 ± 0.962
0.508IleCys: 0.508 ± 0.195
3.387IleAsp: 3.387 ± 0.449
3.218IleGlu: 3.218 ± 0.498
0.931IlePhe: 0.931 ± 0.27
3.048IleGly: 3.048 ± 0.419
0.847IleHis: 0.847 ± 0.254
2.117IleIle: 2.117 ± 0.584
1.778IleLys: 1.778 ± 0.353
2.456IleLeu: 2.456 ± 0.379
0.593IleMet: 0.593 ± 0.222
1.185IleAsn: 1.185 ± 0.383
2.032IlePro: 2.032 ± 0.373
1.778IleGln: 1.778 ± 0.434
3.726IleArg: 3.726 ± 0.502
1.693IleSer: 1.693 ± 0.391
3.048IleThr: 3.048 ± 0.567
2.54IleVal: 2.54 ± 0.382
0.593IleTrp: 0.593 ± 0.2
0.847IleTyr: 0.847 ± 0.282
0.0IleXaa: 0.0 ± 0.0
Lys
5.08LysAla: 5.08 ± 0.843
0.254LysCys: 0.254 ± 0.148
1.185LysAsp: 1.185 ± 0.324
1.778LysGlu: 1.778 ± 0.404
0.677LysPhe: 0.677 ± 0.231
2.794LysGly: 2.794 ± 0.347
0.762LysHis: 0.762 ± 0.216
1.101LysIle: 1.101 ± 0.335
1.524LysLys: 1.524 ± 0.312
3.048LysLeu: 3.048 ± 0.523
0.677LysMet: 0.677 ± 0.291
0.931LysAsn: 0.931 ± 0.291
2.71LysPro: 2.71 ± 0.498
1.355LysGln: 1.355 ± 0.317
3.133LysArg: 3.133 ± 0.69
1.948LysSer: 1.948 ± 0.426
1.863LysThr: 1.863 ± 0.346
2.286LysVal: 2.286 ± 0.407
0.508LysTrp: 0.508 ± 0.178
1.101LysTyr: 1.101 ± 0.328
0.0LysXaa: 0.0 ± 0.0
Leu
13.04LeuAla: 13.04 ± 1.143
0.762LeuCys: 0.762 ± 0.21
6.435LeuAsp: 6.435 ± 0.785
6.351LeuGlu: 6.351 ± 0.698
2.032LeuPhe: 2.032 ± 0.568
7.367LeuGly: 7.367 ± 0.772
2.286LeuHis: 2.286 ± 0.52
3.556LeuIle: 3.556 ± 0.581
3.387LeuLys: 3.387 ± 0.711
8.383LeuLeu: 8.383 ± 0.768
1.778LeuMet: 1.778 ± 0.437
2.794LeuAsn: 2.794 ± 0.428
4.826LeuPro: 4.826 ± 0.709
4.234LeuGln: 4.234 ± 0.626
5.673LeuArg: 5.673 ± 0.525
4.403LeuSer: 4.403 ± 0.569
5.334LeuThr: 5.334 ± 0.8
6.943LeuVal: 6.943 ± 0.841
1.439LeuTrp: 1.439 ± 0.335
2.202LeuTyr: 2.202 ± 0.493
0.0LeuXaa: 0.0 ± 0.0
Met
3.641MetAla: 3.641 ± 0.436
0.085MetCys: 0.085 ± 0.081
2.286MetAsp: 2.286 ± 0.416
1.101MetGlu: 1.101 ± 0.381
0.423MetPhe: 0.423 ± 0.199
1.524MetGly: 1.524 ± 0.321
0.339MetHis: 0.339 ± 0.162
0.508MetIle: 0.508 ± 0.197
0.762MetLys: 0.762 ± 0.219
1.693MetLeu: 1.693 ± 0.358
0.339MetMet: 0.339 ± 0.176
0.423MetAsn: 0.423 ± 0.196
1.27MetPro: 1.27 ± 0.495
1.439MetGln: 1.439 ± 0.377
1.439MetArg: 1.439 ± 0.259
1.948MetSer: 1.948 ± 0.384
1.439MetThr: 1.439 ± 0.35
0.931MetVal: 0.931 ± 0.251
0.169MetTrp: 0.169 ± 0.104
0.254MetTyr: 0.254 ± 0.146
0.0MetXaa: 0.0 ± 0.0
Asn
3.472AsnAla: 3.472 ± 0.617
0.085AsnCys: 0.085 ± 0.088
1.524AsnAsp: 1.524 ± 0.367
1.185AsnGlu: 1.185 ± 0.323
0.508AsnPhe: 0.508 ± 0.233
3.302AsnGly: 3.302 ± 0.517
0.677AsnHis: 0.677 ± 0.23
1.185AsnIle: 1.185 ± 0.338
1.101AsnLys: 1.101 ± 0.339
2.794AsnLeu: 2.794 ± 0.526
0.677AsnMet: 0.677 ± 0.231
1.27AsnAsn: 1.27 ± 0.398
2.371AsnPro: 2.371 ± 0.52
0.931AsnGln: 0.931 ± 0.247
2.456AsnArg: 2.456 ± 0.335
1.609AsnSer: 1.609 ± 0.394
1.101AsnThr: 1.101 ± 0.256
1.101AsnVal: 1.101 ± 0.304
0.931AsnTrp: 0.931 ± 0.233
0.931AsnTyr: 0.931 ± 0.239
0.0AsnXaa: 0.0 ± 0.0
Pro
6.52ProAla: 6.52 ± 0.668
0.762ProCys: 0.762 ± 0.304
3.81ProAsp: 3.81 ± 0.617
2.54ProGlu: 2.54 ± 0.374
1.439ProPhe: 1.439 ± 0.328
4.064ProGly: 4.064 ± 0.662
0.847ProHis: 0.847 ± 0.459
1.948ProIle: 1.948 ± 0.406
1.948ProLys: 1.948 ± 0.398
4.657ProLeu: 4.657 ± 0.488
0.593ProMet: 0.593 ± 0.221
1.778ProAsn: 1.778 ± 0.333
2.202ProPro: 2.202 ± 0.537
2.625ProGln: 2.625 ± 0.476
2.964ProArg: 2.964 ± 0.471
3.387ProSer: 3.387 ± 0.426
2.71ProThr: 2.71 ± 0.56
3.556ProVal: 3.556 ± 0.739
0.762ProTrp: 0.762 ± 0.255
1.355ProTyr: 1.355 ± 0.297
0.0ProXaa: 0.0 ± 0.0
Gln
6.435GlnAla: 6.435 ± 0.686
0.169GlnCys: 0.169 ± 0.102
2.032GlnAsp: 2.032 ± 0.394
2.371GlnGlu: 2.371 ± 0.483
1.355GlnPhe: 1.355 ± 0.317
4.403GlnGly: 4.403 ± 0.582
0.847GlnHis: 0.847 ± 0.218
2.625GlnIle: 2.625 ± 0.416
1.27GlnLys: 1.27 ± 0.419
6.52GlnLeu: 6.52 ± 0.557
0.847GlnMet: 0.847 ± 0.215
1.101GlnAsn: 1.101 ± 0.26
2.202GlnPro: 2.202 ± 0.372
3.98GlnGln: 3.98 ± 0.749
4.064GlnArg: 4.064 ± 0.672
2.794GlnSer: 2.794 ± 0.427
2.202GlnThr: 2.202 ± 0.399
4.911GlnVal: 4.911 ± 0.611
0.593GlnTrp: 0.593 ± 0.214
1.016GlnTyr: 1.016 ± 0.321
0.0GlnXaa: 0.0 ± 0.0
Arg
8.129ArgAla: 8.129 ± 0.811
0.593ArgCys: 0.593 ± 0.201
3.98ArgAsp: 3.98 ± 0.572
4.572ArgGlu: 4.572 ± 0.713
1.948ArgPhe: 1.948 ± 0.386
4.742ArgGly: 4.742 ± 0.591
1.27ArgHis: 1.27 ± 0.292
3.81ArgIle: 3.81 ± 0.541
2.71ArgLys: 2.71 ± 0.454
8.213ArgLeu: 8.213 ± 0.863
1.439ArgMet: 1.439 ± 0.328
1.948ArgAsn: 1.948 ± 0.395
3.641ArgPro: 3.641 ± 0.704
4.234ArgGln: 4.234 ± 0.64
6.097ArgArg: 6.097 ± 0.617
4.572ArgSer: 4.572 ± 0.544
3.387ArgThr: 3.387 ± 0.456
4.149ArgVal: 4.149 ± 0.573
1.693ArgTrp: 1.693 ± 0.354
2.625ArgTyr: 2.625 ± 0.433
0.0ArgXaa: 0.0 ± 0.0
Ser
8.213SerAla: 8.213 ± 0.779
0.762SerCys: 0.762 ± 0.235
3.556SerAsp: 3.556 ± 0.621
2.456SerGlu: 2.456 ± 0.373
1.185SerPhe: 1.185 ± 0.311
4.826SerGly: 4.826 ± 0.741
0.762SerHis: 0.762 ± 0.27
2.71SerIle: 2.71 ± 0.452
1.778SerLys: 1.778 ± 0.425
5.165SerLeu: 5.165 ± 0.549
1.101SerMet: 1.101 ± 0.303
1.948SerAsn: 1.948 ± 0.457
3.218SerPro: 3.218 ± 0.593
2.794SerGln: 2.794 ± 0.378
4.064SerArg: 4.064 ± 0.618
4.403SerSer: 4.403 ± 0.933
3.387SerThr: 3.387 ± 0.515
3.387SerVal: 3.387 ± 0.542
1.101SerTrp: 1.101 ± 0.305
1.863SerTyr: 1.863 ± 0.395
0.0SerXaa: 0.0 ± 0.0
Thr
7.451ThrAla: 7.451 ± 0.9
0.339ThrCys: 0.339 ± 0.278
2.879ThrAsp: 2.879 ± 0.496
2.71ThrGlu: 2.71 ± 0.512
1.609ThrPhe: 1.609 ± 0.327
4.572ThrGly: 4.572 ± 0.71
0.593ThrHis: 0.593 ± 0.224
2.371ThrIle: 2.371 ± 0.359
1.778ThrLys: 1.778 ± 0.391
5.419ThrLeu: 5.419 ± 0.696
1.016ThrMet: 1.016 ± 0.266
1.524ThrAsn: 1.524 ± 0.328
2.54ThrPro: 2.54 ± 0.334
1.948ThrGln: 1.948 ± 0.386
3.387ThrArg: 3.387 ± 0.453
3.895ThrSer: 3.895 ± 0.668
4.064ThrThr: 4.064 ± 0.546
5.588ThrVal: 5.588 ± 0.83
1.016ThrTrp: 1.016 ± 0.28
1.524ThrTyr: 1.524 ± 0.34
0.0ThrXaa: 0.0 ± 0.0
Val
8.467ValAla: 8.467 ± 0.734
0.423ValCys: 0.423 ± 0.188
3.387ValAsp: 3.387 ± 0.606
5.165ValGlu: 5.165 ± 0.697
1.778ValPhe: 1.778 ± 0.296
4.318ValGly: 4.318 ± 0.685
0.508ValHis: 0.508 ± 0.174
2.202ValIle: 2.202 ± 0.425
2.371ValLys: 2.371 ± 0.375
5.927ValLeu: 5.927 ± 0.797
0.931ValMet: 0.931 ± 0.259
1.863ValAsn: 1.863 ± 0.369
3.556ValPro: 3.556 ± 0.493
3.387ValGln: 3.387 ± 0.429
5.08ValArg: 5.08 ± 0.604
4.234ValSer: 4.234 ± 0.543
4.742ValThr: 4.742 ± 0.643
4.572ValVal: 4.572 ± 0.538
1.439ValTrp: 1.439 ± 0.311
2.54ValTyr: 2.54 ± 0.472
0.0ValXaa: 0.0 ± 0.0
Trp
1.948TrpAla: 1.948 ± 0.392
0.423TrpCys: 0.423 ± 0.16
0.677TrpAsp: 0.677 ± 0.192
0.847TrpGlu: 0.847 ± 0.238
0.677TrpPhe: 0.677 ± 0.226
1.016TrpGly: 1.016 ± 0.323
0.085TrpHis: 0.085 ± 0.088
0.931TrpIle: 0.931 ± 0.234
1.016TrpLys: 1.016 ± 0.203
1.693TrpLeu: 1.693 ± 0.335
0.931TrpMet: 0.931 ± 0.309
0.423TrpAsn: 0.423 ± 0.171
1.016TrpPro: 1.016 ± 0.311
1.016TrpGln: 1.016 ± 0.297
1.27TrpArg: 1.27 ± 0.266
1.27TrpSer: 1.27 ± 0.293
0.931TrpThr: 0.931 ± 0.215
1.439TrpVal: 1.439 ± 0.308
0.423TrpTrp: 0.423 ± 0.2
0.169TrpTyr: 0.169 ± 0.156
0.0TrpXaa: 0.0 ± 0.0
Tyr
3.218TyrAla: 3.218 ± 0.434
0.339TyrCys: 0.339 ± 0.175
1.185TyrAsp: 1.185 ± 0.353
1.693TyrGlu: 1.693 ± 0.329
1.101TyrPhe: 1.101 ± 0.234
2.117TyrGly: 2.117 ± 0.423
0.677TyrHis: 0.677 ± 0.255
1.185TyrIle: 1.185 ± 0.332
0.762TyrLys: 0.762 ± 0.3
2.032TyrLeu: 2.032 ± 0.423
0.593TyrMet: 0.593 ± 0.223
1.101TyrAsn: 1.101 ± 0.26
1.609TyrPro: 1.609 ± 0.475
1.355TyrGln: 1.355 ± 0.367
1.948TyrArg: 1.948 ± 0.367
1.863TyrSer: 1.863 ± 0.422
1.693TyrThr: 1.693 ± 0.541
2.117TyrVal: 2.117 ± 0.425
0.254TyrTrp: 0.254 ± 0.195
0.677TyrTyr: 0.677 ± 0.23
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 55 proteins (11811 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski