Amino acid dipepetide frequency for Shahe picorna-like virus 4

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
11.554AlaAla: 11.554 ± 0.0
0.745AlaCys: 0.745 ± 0.0
3.727AlaAsp: 3.727 ± 0.0
4.473AlaGlu: 4.473 ± 0.0
3.727AlaPhe: 3.727 ± 0.0
7.082AlaGly: 7.082 ± 0.0
3.354AlaHis: 3.354 ± 0.0
4.473AlaIle: 4.473 ± 0.0
4.1AlaLys: 4.1 ± 0.0
7.827AlaLeu: 7.827 ± 0.0
2.236AlaMet: 2.236 ± 0.0
2.609AlaAsn: 2.609 ± 0.0
5.218AlaPro: 5.218 ± 0.0
4.473AlaGln: 4.473 ± 0.0
5.963AlaArg: 5.963 ± 0.0
8.2AlaSer: 8.2 ± 0.0
7.454AlaThr: 7.454 ± 0.0
5.591AlaVal: 5.591 ± 0.0
2.236AlaTrp: 2.236 ± 0.0
1.491AlaTyr: 1.491 ± 0.0
0.0AlaXaa: 0.0 ± 0.0
Cys
0.745CysAla: 0.745 ± 0.0
0.0CysCys: 0.0 ± 0.0
1.118CysAsp: 1.118 ± 0.0
0.745CysGlu: 0.745 ± 0.0
1.118CysPhe: 1.118 ± 0.0
2.236CysGly: 2.236 ± 0.0
0.0CysHis: 0.0 ± 0.0
1.491CysIle: 1.491 ± 0.0
0.373CysLys: 0.373 ± 0.0
1.864CysLeu: 1.864 ± 0.0
0.745CysMet: 0.745 ± 0.0
0.0CysAsn: 0.0 ± 0.0
1.118CysPro: 1.118 ± 0.0
0.0CysGln: 0.0 ± 0.0
0.373CysArg: 0.373 ± 0.0
0.373CysSer: 0.373 ± 0.0
1.118CysThr: 1.118 ± 0.0
1.118CysVal: 1.118 ± 0.0
0.0CysTrp: 0.0 ± 0.0
0.0CysTyr: 0.0 ± 0.0
0.0CysXaa: 0.0 ± 0.0
Asp
3.727AspAla: 3.727 ± 0.0
1.118AspCys: 1.118 ± 0.0
3.727AspAsp: 3.727 ± 0.0
4.473AspGlu: 4.473 ± 0.0
2.982AspPhe: 2.982 ± 0.0
1.118AspGly: 1.118 ± 0.0
0.745AspHis: 0.745 ± 0.0
3.354AspIle: 3.354 ± 0.0
4.473AspLys: 4.473 ± 0.0
5.218AspLeu: 5.218 ± 0.0
2.609AspMet: 2.609 ± 0.0
1.491AspAsn: 1.491 ± 0.0
3.354AspPro: 3.354 ± 0.0
0.0AspGln: 0.0 ± 0.0
0.745AspArg: 0.745 ± 0.0
2.982AspSer: 2.982 ± 0.0
3.354AspThr: 3.354 ± 0.0
4.845AspVal: 4.845 ± 0.0
0.745AspTrp: 0.745 ± 0.0
1.118AspTyr: 1.118 ± 0.0
0.0AspXaa: 0.0 ± 0.0
Glu
1.864GluAla: 1.864 ± 0.0
0.373GluCys: 0.373 ± 0.0
4.845GluAsp: 4.845 ± 0.0
5.591GluGlu: 5.591 ± 0.0
2.982GluPhe: 2.982 ± 0.0
4.845GluGly: 4.845 ± 0.0
1.864GluHis: 1.864 ± 0.0
1.864GluIle: 1.864 ± 0.0
1.491GluLys: 1.491 ± 0.0
3.727GluLeu: 3.727 ± 0.0
0.373GluMet: 0.373 ± 0.0
0.745GluAsn: 0.745 ± 0.0
3.727GluPro: 3.727 ± 0.0
2.982GluGln: 2.982 ± 0.0
1.491GluArg: 1.491 ± 0.0
4.473GluSer: 4.473 ± 0.0
1.118GluThr: 1.118 ± 0.0
4.1GluVal: 4.1 ± 0.0
0.373GluTrp: 0.373 ± 0.0
1.864GluTyr: 1.864 ± 0.0
0.0GluXaa: 0.0 ± 0.0
Phe
2.609PheAla: 2.609 ± 0.0
0.745PheCys: 0.745 ± 0.0
5.218PheAsp: 5.218 ± 0.0
1.864PheGlu: 1.864 ± 0.0
2.609PhePhe: 2.609 ± 0.0
3.727PheGly: 3.727 ± 0.0
1.491PheHis: 1.491 ± 0.0
2.982PheIle: 2.982 ± 0.0
1.864PheLys: 1.864 ± 0.0
4.845PheLeu: 4.845 ± 0.0
0.745PheMet: 0.745 ± 0.0
2.609PheAsn: 2.609 ± 0.0
2.609PhePro: 2.609 ± 0.0
2.236PheGln: 2.236 ± 0.0
2.236PheArg: 2.236 ± 0.0
3.354PheSer: 3.354 ± 0.0
4.1PheThr: 4.1 ± 0.0
4.1PheVal: 4.1 ± 0.0
1.491PheTrp: 1.491 ± 0.0
2.236PheTyr: 2.236 ± 0.0
0.0PheXaa: 0.0 ± 0.0
Gly
7.454GlyAla: 7.454 ± 0.0
0.373GlyCys: 0.373 ± 0.0
5.218GlyAsp: 5.218 ± 0.0
3.354GlyGlu: 3.354 ± 0.0
4.473GlyPhe: 4.473 ± 0.0
1.491GlyGly: 1.491 ± 0.0
1.118GlyHis: 1.118 ± 0.0
2.609GlyIle: 2.609 ± 0.0
1.864GlyLys: 1.864 ± 0.0
3.727GlyLeu: 3.727 ± 0.0
1.491GlyMet: 1.491 ± 0.0
1.864GlyAsn: 1.864 ± 0.0
2.236GlyPro: 2.236 ± 0.0
1.491GlyGln: 1.491 ± 0.0
3.354GlyArg: 3.354 ± 0.0
6.709GlySer: 6.709 ± 0.0
5.218GlyThr: 5.218 ± 0.0
5.591GlyVal: 5.591 ± 0.0
1.118GlyTrp: 1.118 ± 0.0
2.609GlyTyr: 2.609 ± 0.0
0.0GlyXaa: 0.0 ± 0.0
His
2.236HisAla: 2.236 ± 0.0
1.118HisCys: 1.118 ± 0.0
0.745HisAsp: 0.745 ± 0.0
0.745HisGlu: 0.745 ± 0.0
0.745HisPhe: 0.745 ± 0.0
2.236HisGly: 2.236 ± 0.0
0.745HisHis: 0.745 ± 0.0
0.745HisIle: 0.745 ± 0.0
1.118HisLys: 1.118 ± 0.0
3.727HisLeu: 3.727 ± 0.0
0.0HisMet: 0.0 ± 0.0
1.118HisAsn: 1.118 ± 0.0
2.236HisPro: 2.236 ± 0.0
0.745HisGln: 0.745 ± 0.0
0.745HisArg: 0.745 ± 0.0
1.491HisSer: 1.491 ± 0.0
0.373HisThr: 0.373 ± 0.0
1.864HisVal: 1.864 ± 0.0
0.0HisTrp: 0.0 ± 0.0
0.373HisTyr: 0.373 ± 0.0
0.0HisXaa: 0.0 ± 0.0
Ile
6.336IleAla: 6.336 ± 0.0
0.373IleCys: 0.373 ± 0.0
2.609IleAsp: 2.609 ± 0.0
3.727IleGlu: 3.727 ± 0.0
1.491IlePhe: 1.491 ± 0.0
1.491IleGly: 1.491 ± 0.0
0.745IleHis: 0.745 ± 0.0
2.609IleIle: 2.609 ± 0.0
2.236IleLys: 2.236 ± 0.0
4.845IleLeu: 4.845 ± 0.0
0.373IleMet: 0.373 ± 0.0
2.236IleAsn: 2.236 ± 0.0
2.982IlePro: 2.982 ± 0.0
1.491IleGln: 1.491 ± 0.0
1.491IleArg: 1.491 ± 0.0
2.236IleSer: 2.236 ± 0.0
2.982IleThr: 2.982 ± 0.0
4.1IleVal: 4.1 ± 0.0
0.0IleTrp: 0.0 ± 0.0
0.373IleTyr: 0.373 ± 0.0
0.0IleXaa: 0.0 ± 0.0
Lys
4.1LysAla: 4.1 ± 0.0
0.373LysCys: 0.373 ± 0.0
1.118LysAsp: 1.118 ± 0.0
2.982LysGlu: 2.982 ± 0.0
2.236LysPhe: 2.236 ± 0.0
2.609LysGly: 2.609 ± 0.0
0.745LysHis: 0.745 ± 0.0
2.609LysIle: 2.609 ± 0.0
3.727LysLys: 3.727 ± 0.0
3.727LysLeu: 3.727 ± 0.0
1.491LysMet: 1.491 ± 0.0
2.236LysAsn: 2.236 ± 0.0
0.373LysPro: 0.373 ± 0.0
0.0LysGln: 0.0 ± 0.0
2.609LysArg: 2.609 ± 0.0
2.609LysSer: 2.609 ± 0.0
1.491LysThr: 1.491 ± 0.0
1.864LysVal: 1.864 ± 0.0
0.745LysTrp: 0.745 ± 0.0
1.491LysTyr: 1.491 ± 0.0
0.0LysXaa: 0.0 ± 0.0
Leu
8.945LeuAla: 8.945 ± 0.0
0.745LeuCys: 0.745 ± 0.0
2.609LeuAsp: 2.609 ± 0.0
2.982LeuGlu: 2.982 ± 0.0
4.1LeuPhe: 4.1 ± 0.0
7.082LeuGly: 7.082 ± 0.0
0.745LeuHis: 0.745 ± 0.0
1.118LeuIle: 1.118 ± 0.0
3.354LeuLys: 3.354 ± 0.0
5.963LeuLeu: 5.963 ± 0.0
1.118LeuMet: 1.118 ± 0.0
4.1LeuAsn: 4.1 ± 0.0
4.1LeuPro: 4.1 ± 0.0
1.491LeuGln: 1.491 ± 0.0
5.218LeuArg: 5.218 ± 0.0
8.572LeuSer: 8.572 ± 0.0
6.709LeuThr: 6.709 ± 0.0
7.454LeuVal: 7.454 ± 0.0
0.0LeuTrp: 0.0 ± 0.0
2.982LeuTyr: 2.982 ± 0.0
0.0LeuXaa: 0.0 ± 0.0
Met
0.745MetAla: 0.745 ± 0.0
0.745MetCys: 0.745 ± 0.0
1.118MetAsp: 1.118 ± 0.0
0.0MetGlu: 0.0 ± 0.0
1.864MetPhe: 1.864 ± 0.0
2.236MetGly: 2.236 ± 0.0
0.373MetHis: 0.373 ± 0.0
1.118MetIle: 1.118 ± 0.0
0.373MetLys: 0.373 ± 0.0
2.609MetLeu: 2.609 ± 0.0
0.373MetMet: 0.373 ± 0.0
0.373MetAsn: 0.373 ± 0.0
1.118MetPro: 1.118 ± 0.0
0.745MetGln: 0.745 ± 0.0
2.982MetArg: 2.982 ± 0.0
1.491MetSer: 1.491 ± 0.0
1.491MetThr: 1.491 ± 0.0
1.118MetVal: 1.118 ± 0.0
0.0MetTrp: 0.0 ± 0.0
1.864MetTyr: 1.864 ± 0.0
0.0MetXaa: 0.0 ± 0.0
Asn
3.354AsnAla: 3.354 ± 0.0
0.373AsnCys: 0.373 ± 0.0
1.864AsnAsp: 1.864 ± 0.0
1.864AsnGlu: 1.864 ± 0.0
1.864AsnPhe: 1.864 ± 0.0
2.609AsnGly: 2.609 ± 0.0
1.118AsnHis: 1.118 ± 0.0
1.864AsnIle: 1.864 ± 0.0
0.373AsnLys: 0.373 ± 0.0
2.982AsnLeu: 2.982 ± 0.0
0.745AsnMet: 0.745 ± 0.0
1.491AsnAsn: 1.491 ± 0.0
1.864AsnPro: 1.864 ± 0.0
1.118AsnGln: 1.118 ± 0.0
1.118AsnArg: 1.118 ± 0.0
1.864AsnSer: 1.864 ± 0.0
2.982AsnThr: 2.982 ± 0.0
4.845AsnVal: 4.845 ± 0.0
1.118AsnTrp: 1.118 ± 0.0
0.745AsnTyr: 0.745 ± 0.0
0.0AsnXaa: 0.0 ± 0.0
Pro
5.218ProAla: 5.218 ± 0.0
0.373ProCys: 0.373 ± 0.0
2.609ProAsp: 2.609 ± 0.0
1.491ProGlu: 1.491 ± 0.0
2.982ProPhe: 2.982 ± 0.0
2.982ProGly: 2.982 ± 0.0
0.745ProHis: 0.745 ± 0.0
1.864ProIle: 1.864 ± 0.0
3.727ProLys: 3.727 ± 0.0
3.354ProLeu: 3.354 ± 0.0
0.373ProMet: 0.373 ± 0.0
0.745ProAsn: 0.745 ± 0.0
2.982ProPro: 2.982 ± 0.0
2.609ProGln: 2.609 ± 0.0
2.982ProArg: 2.982 ± 0.0
4.473ProSer: 4.473 ± 0.0
4.473ProThr: 4.473 ± 0.0
6.709ProVal: 6.709 ± 0.0
1.864ProTrp: 1.864 ± 0.0
2.236ProTyr: 2.236 ± 0.0
0.0ProXaa: 0.0 ± 0.0
Gln
4.473GlnAla: 4.473 ± 0.0
0.373GlnCys: 0.373 ± 0.0
1.864GlnAsp: 1.864 ± 0.0
1.491GlnGlu: 1.491 ± 0.0
1.864GlnPhe: 1.864 ± 0.0
1.118GlnGly: 1.118 ± 0.0
1.118GlnHis: 1.118 ± 0.0
2.982GlnIle: 2.982 ± 0.0
0.373GlnLys: 0.373 ± 0.0
2.236GlnLeu: 2.236 ± 0.0
1.118GlnMet: 1.118 ± 0.0
0.745GlnAsn: 0.745 ± 0.0
1.118GlnPro: 1.118 ± 0.0
1.118GlnGln: 1.118 ± 0.0
2.609GlnArg: 2.609 ± 0.0
2.982GlnSer: 2.982 ± 0.0
1.864GlnThr: 1.864 ± 0.0
1.118GlnVal: 1.118 ± 0.0
0.373GlnTrp: 0.373 ± 0.0
1.491GlnTyr: 1.491 ± 0.0
0.0GlnXaa: 0.0 ± 0.0
Arg
5.963ArgAla: 5.963 ± 0.0
0.745ArgCys: 0.745 ± 0.0
1.864ArgAsp: 1.864 ± 0.0
2.609ArgGlu: 2.609 ± 0.0
3.727ArgPhe: 3.727 ± 0.0
2.609ArgGly: 2.609 ± 0.0
1.118ArgHis: 1.118 ± 0.0
1.864ArgIle: 1.864 ± 0.0
1.491ArgLys: 1.491 ± 0.0
3.727ArgLeu: 3.727 ± 0.0
0.745ArgMet: 0.745 ± 0.0
2.236ArgAsn: 2.236 ± 0.0
3.727ArgPro: 3.727 ± 0.0
1.491ArgGln: 1.491 ± 0.0
2.982ArgArg: 2.982 ± 0.0
4.473ArgSer: 4.473 ± 0.0
2.609ArgThr: 2.609 ± 0.0
3.354ArgVal: 3.354 ± 0.0
1.118ArgTrp: 1.118 ± 0.0
1.864ArgTyr: 1.864 ± 0.0
0.0ArgXaa: 0.0 ± 0.0
Ser
9.318SerAla: 9.318 ± 0.0
0.745SerCys: 0.745 ± 0.0
2.609SerAsp: 2.609 ± 0.0
4.1SerGlu: 4.1 ± 0.0
5.963SerPhe: 5.963 ± 0.0
5.218SerGly: 5.218 ± 0.0
1.864SerHis: 1.864 ± 0.0
3.354SerIle: 3.354 ± 0.0
2.982SerLys: 2.982 ± 0.0
4.473SerLeu: 4.473 ± 0.0
3.354SerMet: 3.354 ± 0.0
4.1SerAsn: 4.1 ± 0.0
2.609SerPro: 2.609 ± 0.0
2.982SerGln: 2.982 ± 0.0
2.982SerArg: 2.982 ± 0.0
6.336SerSer: 6.336 ± 0.0
8.2SerThr: 8.2 ± 0.0
8.2SerVal: 8.2 ± 0.0
1.491SerTrp: 1.491 ± 0.0
2.609SerTyr: 2.609 ± 0.0
0.0SerXaa: 0.0 ± 0.0
Thr
4.845ThrAla: 4.845 ± 0.0
1.491ThrCys: 1.491 ± 0.0
2.609ThrAsp: 2.609 ± 0.0
1.864ThrGlu: 1.864 ± 0.0
4.1ThrPhe: 4.1 ± 0.0
2.609ThrGly: 2.609 ± 0.0
0.373ThrHis: 0.373 ± 0.0
4.1ThrIle: 4.1 ± 0.0
1.864ThrLys: 1.864 ± 0.0
3.354ThrLeu: 3.354 ± 0.0
1.491ThrMet: 1.491 ± 0.0
3.727ThrAsn: 3.727 ± 0.0
7.082ThrPro: 7.082 ± 0.0
2.236ThrGln: 2.236 ± 0.0
5.218ThrArg: 5.218 ± 0.0
7.454ThrSer: 7.454 ± 0.0
7.082ThrThr: 7.082 ± 0.0
5.963ThrVal: 5.963 ± 0.0
0.745ThrTrp: 0.745 ± 0.0
2.982ThrTyr: 2.982 ± 0.0
0.0ThrXaa: 0.0 ± 0.0
Val
7.454ValAla: 7.454 ± 0.0
2.609ValCys: 2.609 ± 0.0
3.354ValAsp: 3.354 ± 0.0
5.218ValGlu: 5.218 ± 0.0
3.354ValPhe: 3.354 ± 0.0
5.218ValGly: 5.218 ± 0.0
2.609ValHis: 2.609 ± 0.0
3.354ValIle: 3.354 ± 0.0
1.491ValLys: 1.491 ± 0.0
5.963ValLeu: 5.963 ± 0.0
2.609ValMet: 2.609 ± 0.0
2.236ValAsn: 2.236 ± 0.0
5.591ValPro: 5.591 ± 0.0
2.609ValGln: 2.609 ± 0.0
4.1ValArg: 4.1 ± 0.0
9.691ValSer: 9.691 ± 0.0
3.354ValThr: 3.354 ± 0.0
6.709ValVal: 6.709 ± 0.0
1.864ValTrp: 1.864 ± 0.0
2.982ValTyr: 2.982 ± 0.0
0.0ValXaa: 0.0 ± 0.0
Trp
1.864TrpAla: 1.864 ± 0.0
0.373TrpCys: 0.373 ± 0.0
1.491TrpAsp: 1.491 ± 0.0
0.373TrpGlu: 0.373 ± 0.0
0.745TrpPhe: 0.745 ± 0.0
0.0TrpGly: 0.0 ± 0.0
0.745TrpHis: 0.745 ± 0.0
0.0TrpIle: 0.0 ± 0.0
0.0TrpLys: 0.0 ± 0.0
1.864TrpLeu: 1.864 ± 0.0
0.0TrpMet: 0.0 ± 0.0
0.745TrpAsn: 0.745 ± 0.0
0.373TrpPro: 0.373 ± 0.0
1.118TrpGln: 1.118 ± 0.0
0.745TrpArg: 0.745 ± 0.0
2.236TrpSer: 2.236 ± 0.0
1.118TrpThr: 1.118 ± 0.0
0.745TrpVal: 0.745 ± 0.0
0.0TrpTrp: 0.0 ± 0.0
1.118TrpTyr: 1.118 ± 0.0
0.0TrpXaa: 0.0 ± 0.0
Tyr
3.727TyrAla: 3.727 ± 0.0
0.745TyrCys: 0.745 ± 0.0
1.864TyrAsp: 1.864 ± 0.0
0.745TyrGlu: 0.745 ± 0.0
0.745TyrPhe: 0.745 ± 0.0
4.845TyrGly: 4.845 ± 0.0
1.491TyrHis: 1.491 ± 0.0
0.373TyrIle: 0.373 ± 0.0
1.864TyrLys: 1.864 ± 0.0
3.354TyrLeu: 3.354 ± 0.0
0.373TyrMet: 0.373 ± 0.0
0.745TyrAsn: 0.745 ± 0.0
0.745TyrPro: 0.745 ± 0.0
1.491TyrGln: 1.491 ± 0.0
0.373TyrArg: 0.373 ± 0.0
1.491TyrSer: 1.491 ± 0.0
4.1TyrThr: 4.1 ± 0.0
2.982TyrVal: 2.982 ± 0.0
0.373TyrTrp: 0.373 ± 0.0
1.118TyrTyr: 1.118 ± 0.0
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 1 proteins (2684 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski