Amino acid dipepetide frequency for Carrot mottle virus

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
2.88AlaAla: 2.88 ± 0.356
0.0AlaCys: 0.0 ± 0.0
4.032AlaAsp: 4.032 ± 0.852
5.76AlaGlu: 5.76 ± 1.999
4.032AlaPhe: 4.032 ± 1.123
2.88AlaGly: 2.88 ± 1.209
0.576AlaHis: 0.576 ± 0.782
2.304AlaIle: 2.304 ± 0.601
3.456AlaLys: 3.456 ± 2.048
5.76AlaLeu: 5.76 ± 1.009
4.032AlaMet: 4.032 ± 1.122
2.304AlaAsn: 2.304 ± 1.076
6.912AlaPro: 6.912 ± 0.804
4.032AlaGln: 4.032 ± 1.049
8.065AlaArg: 8.065 ± 5.48
8.641AlaSer: 8.641 ± 1.401
1.152AlaThr: 1.152 ± 0.538
9.793AlaVal: 9.793 ± 2.244
0.576AlaTrp: 0.576 ± 0.782
2.88AlaTyr: 2.88 ± 2.131
0.0AlaXaa: 0.0 ± 0.0
Cys
1.152CysAla: 1.152 ± 0.538
1.152CysCys: 1.152 ± 0.538
0.0CysAsp: 0.0 ± 0.0
1.152CysGlu: 1.152 ± 0.538
1.152CysPhe: 1.152 ± 0.555
3.456CysGly: 3.456 ± 1.12
0.0CysHis: 0.0 ± 0.0
1.728CysIle: 1.728 ± 0.701
0.576CysLys: 0.576 ± 0.341
0.0CysLeu: 0.0 ± 0.0
0.576CysMet: 0.576 ± 0.506
0.0CysAsn: 0.0 ± 0.0
2.304CysPro: 2.304 ± 1.379
1.728CysGln: 1.728 ± 1.024
1.152CysArg: 1.152 ± 0.683
1.728CysSer: 1.728 ± 0.606
0.576CysThr: 0.576 ± 0.341
1.152CysVal: 1.152 ± 0.683
0.0CysTrp: 0.0 ± 0.0
0.0CysTyr: 0.0 ± 0.0
0.0CysXaa: 0.0 ± 0.0
Asp
5.76AspAla: 5.76 ± 2.0
0.576AspCys: 0.576 ± 0.341
3.456AspAsp: 3.456 ± 0.799
4.032AspGlu: 4.032 ± 1.112
1.728AspPhe: 1.728 ± 0.606
4.608AspGly: 4.608 ± 1.099
0.0AspHis: 0.0 ± 0.0
2.304AspIle: 2.304 ± 0.823
1.728AspLys: 1.728 ± 1.024
4.032AspLeu: 4.032 ± 0.361
1.152AspMet: 1.152 ± 0.555
2.88AspAsn: 2.88 ± 0.711
4.608AspPro: 4.608 ± 1.646
1.152AspGln: 1.152 ± 0.685
2.304AspArg: 2.304 ± 1.37
4.608AspSer: 4.608 ± 0.582
4.032AspThr: 4.032 ± 1.219
5.184AspVal: 5.184 ± 2.05
0.576AspTrp: 0.576 ± 0.341
1.152AspTyr: 1.152 ± 0.685
0.0AspXaa: 0.0 ± 0.0
Glu
4.032GluAla: 4.032 ± 0.852
0.576GluCys: 0.576 ± 0.782
2.304GluAsp: 2.304 ± 0.689
1.728GluGlu: 1.728 ± 0.671
1.728GluPhe: 1.728 ± 1.024
9.217GluGly: 9.217 ± 1.718
2.88GluHis: 2.88 ± 1.094
0.576GluIle: 0.576 ± 0.341
2.304GluLys: 2.304 ± 1.111
8.641GluLeu: 8.641 ± 2.13
1.152GluMet: 1.152 ± 0.538
1.152GluAsn: 1.152 ± 0.538
3.456GluPro: 3.456 ± 1.056
2.88GluGln: 2.88 ± 0.757
5.184GluArg: 5.184 ± 1.645
2.304GluSer: 2.304 ± 0.55
1.728GluThr: 1.728 ± 0.671
2.304GluVal: 2.304 ± 0.689
1.152GluTrp: 1.152 ± 0.538
0.0GluTyr: 0.0 ± 0.0
0.0GluXaa: 0.0 ± 0.0
Phe
2.88PheAla: 2.88 ± 0.711
1.152PheCys: 1.152 ± 0.538
2.304PheAsp: 2.304 ± 1.365
1.152PheGlu: 1.152 ± 1.564
0.576PhePhe: 0.576 ± 0.598
1.728PheGly: 1.728 ± 0.606
0.576PheHis: 0.576 ± 0.782
1.728PheIle: 1.728 ± 0.701
1.728PheLys: 1.728 ± 1.024
2.304PheLeu: 2.304 ± 0.55
0.0PheMet: 0.0 ± 0.0
2.304PheAsn: 2.304 ± 1.365
0.576PhePro: 0.576 ± 0.341
1.728PheGln: 1.728 ± 0.748
1.728PheArg: 1.728 ± 0.748
4.032PheSer: 4.032 ± 1.52
1.728PheThr: 1.728 ± 1.024
2.304PheVal: 2.304 ± 0.601
0.0PheTrp: 0.0 ± 0.0
1.728PheTyr: 1.728 ± 0.701
0.0PheXaa: 0.0 ± 0.0
Gly
4.608GlyAla: 4.608 ± 1.9
2.88GlyCys: 2.88 ± 0.595
2.304GlyAsp: 2.304 ± 0.94
2.304GlyGlu: 2.304 ± 1.788
1.728GlyPhe: 1.728 ± 1.024
6.336GlyGly: 6.336 ± 1.263
1.152GlyHis: 1.152 ± 0.685
4.608GlyIle: 4.608 ± 0.694
0.576GlyLys: 0.576 ± 0.782
4.608GlyLeu: 4.608 ± 0.582
1.728GlyMet: 1.728 ± 0.701
4.032GlyAsn: 4.032 ± 0.852
7.488GlyPro: 7.488 ± 1.989
2.304GlyGln: 2.304 ± 1.823
6.912GlyArg: 6.912 ± 0.786
2.88GlySer: 2.88 ± 1.218
9.217GlyThr: 9.217 ± 1.566
11.521GlyVal: 11.521 ± 3.123
0.0GlyTrp: 0.0 ± 0.0
1.152GlyTyr: 1.152 ± 0.538
0.0GlyXaa: 0.0 ± 0.0
His
4.032HisAla: 4.032 ± 2.808
0.0HisCys: 0.0 ± 0.0
1.728HisAsp: 1.728 ± 0.701
2.304HisGlu: 2.304 ± 0.55
0.0HisPhe: 0.0 ± 0.0
1.728HisGly: 1.728 ± 1.103
0.576HisHis: 0.576 ± 0.598
0.576HisIle: 0.576 ± 0.341
0.576HisLys: 0.576 ± 0.341
2.304HisLeu: 2.304 ± 0.55
0.0HisMet: 0.0 ± 0.0
1.152HisAsn: 1.152 ± 0.555
3.456HisPro: 3.456 ± 0.109
1.152HisGln: 1.152 ± 1.564
1.728HisArg: 1.728 ± 1.57
3.456HisSer: 3.456 ± 1.96
0.576HisThr: 0.576 ± 0.598
3.456HisVal: 3.456 ± 1.056
0.0HisTrp: 0.0 ± 0.0
0.0HisTyr: 0.0 ± 0.0
0.0HisXaa: 0.0 ± 0.0
Ile
1.728IleAla: 1.728 ± 1.024
0.576IleCys: 0.576 ± 0.341
1.728IleAsp: 1.728 ± 0.701
2.88IleGlu: 2.88 ± 0.994
0.576IlePhe: 0.576 ± 0.341
1.728IleGly: 1.728 ± 0.701
1.728IleHis: 1.728 ± 0.695
1.152IleIle: 1.152 ± 0.685
1.728IleLys: 1.728 ± 1.024
4.032IleLeu: 4.032 ± 1.54
0.576IleMet: 0.576 ± 0.598
1.728IleAsn: 1.728 ± 0.701
6.912IlePro: 6.912 ± 0.893
1.152IleGln: 1.152 ± 0.555
1.152IleArg: 1.152 ± 0.683
2.304IleSer: 2.304 ± 0.823
1.728IleThr: 1.728 ± 0.606
1.152IleVal: 1.152 ± 0.555
0.576IleTrp: 0.576 ± 0.598
2.88IleTyr: 2.88 ± 1.394
0.0IleXaa: 0.0 ± 0.0
Lys
1.728LysAla: 1.728 ± 1.024
0.576LysCys: 0.576 ± 0.341
1.728LysAsp: 1.728 ± 1.024
1.152LysGlu: 1.152 ± 0.683
1.728LysPhe: 1.728 ± 1.024
3.456LysGly: 3.456 ± 1.413
2.304LysHis: 2.304 ± 0.823
0.576LysIle: 0.576 ± 0.341
1.152LysLys: 1.152 ± 0.555
1.152LysLeu: 1.152 ± 0.555
0.576LysMet: 0.576 ± 0.341
1.728LysAsn: 1.728 ± 0.606
2.88LysPro: 2.88 ± 1.707
0.0LysGln: 0.0 ± 0.0
2.88LysArg: 2.88 ± 1.105
0.576LysSer: 0.576 ± 0.598
1.152LysThr: 1.152 ± 1.197
4.608LysVal: 4.608 ± 0.694
1.152LysTrp: 1.152 ± 0.683
1.152LysTyr: 1.152 ± 0.685
0.0LysXaa: 0.0 ± 0.0
Leu
5.76LeuAla: 5.76 ± 1.373
2.304LeuCys: 2.304 ± 0.94
3.456LeuAsp: 3.456 ± 1.212
5.76LeuGlu: 5.76 ± 1.132
2.304LeuPhe: 2.304 ± 1.377
8.065LeuGly: 8.065 ± 0.627
2.304LeuHis: 2.304 ± 1.109
1.728LeuIle: 1.728 ± 0.671
4.608LeuLys: 4.608 ± 1.685
4.608LeuLeu: 4.608 ± 0.775
1.728LeuMet: 1.728 ± 1.024
0.0LeuAsn: 0.0 ± 0.0
3.456LeuPro: 3.456 ± 2.219
2.304LeuGln: 2.304 ± 0.55
5.184LeuArg: 5.184 ± 2.013
8.641LeuSer: 8.641 ± 2.792
2.88LeuThr: 2.88 ± 1.641
5.184LeuVal: 5.184 ± 1.812
1.152LeuTrp: 1.152 ± 0.538
4.608LeuTyr: 4.608 ± 1.306
0.0LeuXaa: 0.0 ± 0.0
Met
2.304MetAla: 2.304 ± 1.076
0.0MetCys: 0.0 ± 0.0
1.728MetAsp: 1.728 ± 1.024
3.456MetGlu: 3.456 ± 0.997
0.0MetPhe: 0.0 ± 0.0
1.152MetGly: 1.152 ± 0.555
0.0MetHis: 0.0 ± 0.0
0.0MetIle: 0.0 ± 0.0
0.576MetLys: 0.576 ± 0.341
1.152MetLeu: 1.152 ± 0.555
0.0MetMet: 0.0 ± 0.0
0.576MetAsn: 0.576 ± 0.598
2.304MetPro: 2.304 ± 1.076
1.152MetGln: 1.152 ± 0.683
0.576MetArg: 0.576 ± 0.598
1.728MetSer: 1.728 ± 0.606
2.88MetThr: 2.88 ± 0.356
2.304MetVal: 2.304 ± 0.953
0.576MetTrp: 0.576 ± 0.598
0.576MetTyr: 0.576 ± 0.341
0.0MetXaa: 0.0 ± 0.0
Asn
2.304AsnAla: 2.304 ± 0.601
1.728AsnCys: 1.728 ± 0.606
1.152AsnAsp: 1.152 ± 0.555
0.576AsnGlu: 0.576 ± 0.341
0.576AsnPhe: 0.576 ± 0.341
0.576AsnGly: 0.576 ± 0.341
0.576AsnHis: 0.576 ± 0.782
1.152AsnIle: 1.152 ± 0.555
0.576AsnLys: 0.576 ± 0.341
2.304AsnLeu: 2.304 ± 0.601
0.0AsnMet: 0.0 ± 0.0
2.88AsnAsn: 2.88 ± 0.356
3.456AsnPro: 3.456 ± 0.845
0.0AsnGln: 0.0 ± 0.0
2.304AsnArg: 2.304 ± 0.55
4.032AsnSer: 4.032 ± 0.852
2.88AsnThr: 2.88 ± 1.036
2.304AsnVal: 2.304 ± 0.823
0.0AsnTrp: 0.0 ± 0.0
1.728AsnTyr: 1.728 ± 0.671
0.0AsnXaa: 0.0 ± 0.0
Pro
11.521ProAla: 11.521 ± 4.198
2.304ProCys: 2.304 ± 0.55
4.608ProAsp: 4.608 ± 1.203
4.032ProGlu: 4.032 ± 0.622
0.576ProPhe: 0.576 ± 0.341
4.032ProGly: 4.032 ± 1.112
3.456ProHis: 3.456 ± 1.401
2.88ProIle: 2.88 ± 0.356
1.152ProLys: 1.152 ± 0.683
6.336ProLeu: 6.336 ± 1.692
2.304ProMet: 2.304 ± 0.823
0.576ProAsn: 0.576 ± 0.598
5.76ProPro: 5.76 ± 2.624
0.0ProGln: 0.0 ± 0.0
5.76ProArg: 5.76 ± 1.132
4.608ProSer: 4.608 ± 1.099
8.065ProThr: 8.065 ± 2.311
9.793ProVal: 9.793 ± 1.673
1.152ProTrp: 1.152 ± 0.685
0.576ProTyr: 0.576 ± 0.341
0.0ProXaa: 0.0 ± 0.0
Gln
0.576GlnAla: 0.576 ± 0.598
0.0GlnCys: 0.0 ± 0.0
2.304GlnAsp: 2.304 ± 0.55
2.88GlnGlu: 2.88 ± 0.967
1.152GlnPhe: 1.152 ± 0.538
2.304GlnGly: 2.304 ± 0.689
1.152GlnHis: 1.152 ± 0.685
1.152GlnIle: 1.152 ± 0.683
0.576GlnLys: 0.576 ± 0.598
5.76GlnLeu: 5.76 ± 2.071
0.0GlnMet: 0.0 ± 0.0
0.0GlnAsn: 0.0 ± 0.0
3.456GlnPro: 3.456 ± 0.989
1.728GlnGln: 1.728 ± 0.606
2.88GlnArg: 2.88 ± 1.638
3.456GlnSer: 3.456 ± 1.401
1.728GlnThr: 1.728 ± 1.024
2.88GlnVal: 2.88 ± 1.707
0.576GlnTrp: 0.576 ± 0.341
1.728GlnTyr: 1.728 ± 0.695
0.0GlnXaa: 0.0 ± 0.0
Arg
5.76ArgAla: 5.76 ± 1.646
0.576ArgCys: 0.576 ± 0.598
8.641ArgAsp: 8.641 ± 0.437
2.88ArgGlu: 2.88 ± 1.25
4.032ArgPhe: 4.032 ± 0.361
6.336ArgGly: 6.336 ± 2.216
2.304ArgHis: 2.304 ± 2.314
2.88ArgIle: 2.88 ± 0.595
0.0ArgLys: 0.0 ± 0.0
4.608ArgLeu: 4.608 ± 1.289
4.032ArgMet: 4.032 ± 0.669
0.576ArgAsn: 0.576 ± 0.782
3.456ArgPro: 3.456 ± 1.497
1.152ArgGln: 1.152 ± 0.555
3.456ArgArg: 3.456 ± 2.047
4.608ArgSer: 4.608 ± 0.955
2.304ArgThr: 2.304 ± 1.788
6.336ArgVal: 6.336 ± 2.221
1.728ArgTrp: 1.728 ± 0.671
2.88ArgTyr: 2.88 ± 0.994
0.0ArgXaa: 0.0 ± 0.0
Ser
5.76SerAla: 5.76 ± 0.711
0.0SerCys: 0.0 ± 0.0
2.304SerAsp: 2.304 ± 0.689
3.456SerGlu: 3.456 ± 1.391
3.456SerPhe: 3.456 ± 0.799
5.76SerGly: 5.76 ± 0.752
2.304SerHis: 2.304 ± 1.377
4.032SerIle: 4.032 ± 1.302
2.88SerLys: 2.88 ± 0.711
5.184SerLeu: 5.184 ± 1.124
2.88SerMet: 2.88 ± 1.036
2.304SerAsn: 2.304 ± 0.55
5.76SerPro: 5.76 ± 0.971
5.184SerGln: 5.184 ± 1.321
2.304SerArg: 2.304 ± 0.953
9.217SerSer: 9.217 ± 1.632
5.76SerThr: 5.76 ± 1.556
6.912SerVal: 6.912 ± 1.368
0.576SerTrp: 0.576 ± 0.341
1.728SerTyr: 1.728 ± 0.701
0.0SerXaa: 0.0 ± 0.0
Thr
5.76ThrAla: 5.76 ± 0.971
1.728ThrCys: 1.728 ± 0.606
1.728ThrAsp: 1.728 ± 0.695
2.304ThrGlu: 2.304 ± 1.076
1.728ThrPhe: 1.728 ± 0.701
6.336ThrGly: 6.336 ± 1.892
2.88ThrHis: 2.88 ± 0.356
0.576ThrIle: 0.576 ± 0.341
2.304ThrLys: 2.304 ± 0.601
2.88ThrLeu: 2.88 ± 1.087
1.728ThrMet: 1.728 ± 0.606
1.728ThrAsn: 1.728 ± 1.103
2.88ThrPro: 2.88 ± 1.25
4.032ThrGln: 4.032 ± 1.52
5.184ThrArg: 5.184 ± 0.799
5.76ThrSer: 5.76 ± 1.135
5.184ThrThr: 5.184 ± 3.227
3.456ThrVal: 3.456 ± 0.997
0.0ThrTrp: 0.0 ± 0.0
0.0ThrTyr: 0.0 ± 0.0
0.0ThrXaa: 0.0 ± 0.0
Val
9.793ValAla: 9.793 ± 0.864
3.456ValCys: 3.456 ± 0.94
8.065ValAsp: 8.065 ± 3.052
6.336ValGlu: 6.336 ± 2.283
2.304ValPhe: 2.304 ± 0.953
4.032ValGly: 4.032 ± 0.852
3.456ValHis: 3.456 ± 0.817
5.184ValIle: 5.184 ± 1.623
2.304ValLys: 2.304 ± 0.94
6.336ValLeu: 6.336 ± 1.613
0.0ValMet: 0.0 ± 0.0
2.88ValAsn: 2.88 ± 1.094
8.065ValPro: 8.065 ± 1.599
2.88ValGln: 2.88 ± 1.094
6.336ValArg: 6.336 ± 0.851
3.456ValSer: 3.456 ± 1.413
1.728ValThr: 1.728 ± 0.671
2.88ValVal: 2.88 ± 1.105
0.0ValTrp: 0.0 ± 0.0
5.76ValTyr: 5.76 ± 1.32
0.0ValXaa: 0.0 ± 0.0
Trp
0.0TrpAla: 0.0 ± 0.0
0.0TrpCys: 0.0 ± 0.0
1.152TrpAsp: 1.152 ± 0.685
0.576TrpGlu: 0.576 ± 0.341
1.728TrpPhe: 1.728 ± 0.606
1.152TrpGly: 1.152 ± 0.538
0.576TrpHis: 0.576 ± 0.782
0.0TrpIle: 0.0 ± 0.0
0.0TrpLys: 0.0 ± 0.0
0.576TrpLeu: 0.576 ± 0.341
0.0TrpMet: 0.0 ± 0.0
0.0TrpAsn: 0.0 ± 0.0
0.0TrpPro: 0.0 ± 0.0
0.576TrpGln: 0.576 ± 0.598
1.728TrpArg: 1.728 ± 0.701
0.0TrpSer: 0.0 ± 0.0
0.576TrpThr: 0.576 ± 0.341
0.576TrpVal: 0.576 ± 0.598
0.576TrpTrp: 0.576 ± 0.341
1.152TrpTyr: 1.152 ± 0.538
0.0TrpXaa: 0.0 ± 0.0
Tyr
1.728TyrAla: 1.728 ± 0.695
0.0TyrCys: 0.0 ± 0.0
1.152TyrAsp: 1.152 ± 0.685
0.576TyrGlu: 0.576 ± 0.341
1.152TyrPhe: 1.152 ± 0.685
3.456TyrGly: 3.456 ± 1.12
0.0TyrHis: 0.0 ± 0.0
2.88TyrIle: 2.88 ± 1.094
3.456TyrLys: 3.456 ± 2.048
3.456TyrLeu: 3.456 ± 1.025
0.0TyrMet: 0.0 ± 0.0
2.304TyrAsn: 2.304 ± 0.55
2.304TyrPro: 2.304 ± 1.823
1.152TyrGln: 1.152 ± 0.685
2.304TyrArg: 2.304 ± 1.379
1.728TyrSer: 1.728 ± 1.103
2.304TyrThr: 2.304 ± 0.55
1.152TyrVal: 1.152 ± 0.538
0.576TyrTrp: 0.576 ± 0.341
1.152TyrTyr: 1.152 ± 0.538
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 4 proteins (1737 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski