Hubei picorna-like virus 52
Average proteome isoelectric point is 5.98
Get precalculated fractions of proteins
Acidic
pI < 6.8
6.8-7.4
pI > 7.4
Basic
All
Note: above files contain also dissociation constants (pKa)
Virtual 2D-PAGE plot for 1 proteins (isoelectric point calculated using IPC2_protein)
Get csv file with sequences according to given criteria:
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Summary statistics related to proteome-wise predictions
Protein with the lowest isoelectric point:
>tr|A0A1L3KKW6|A0A1L3KKW6_9VIRU RdRP_1 domain-containing protein OS=Hubei picorna-like virus 52 OX=1923134 PE=4 SV=1
MM1 pKa = 6.42 QTTMVNTMYY10 pKa = 10.05 MIKK13 pKa = 10.33 AKK15 pKa = 8.68 QFKK18 pKa = 8.72 RR19 pKa = 11.84 QHH21 pKa = 5.61 RR22 pKa = 11.84 VLVEE26 pKa = 3.77 EE27 pKa = 4.58 QILKK31 pKa = 10.48 EE32 pKa = 4.44 DD33 pKa = 4.46 LDD35 pKa = 3.95 FQPRR39 pKa = 11.84 EE40 pKa = 3.92 PRR42 pKa = 11.84 QLFSNVEE49 pKa = 4.31 YY50 pKa = 10.24 IWEE53 pKa = 4.2 CFPNYY58 pKa = 9.36 EE59 pKa = 4.69 HH60 pKa = 7.51 INYY63 pKa = 10.15 SLFKK67 pKa = 10.51 RR68 pKa = 11.84 DD69 pKa = 3.11 VDD71 pKa = 3.63 EE72 pKa = 5.58 LKK74 pKa = 10.6 ILLRR78 pKa = 11.84 SIQRR82 pKa = 11.84 QFNIYY87 pKa = 8.98 EE88 pKa = 4.21 RR89 pKa = 11.84 NSKK92 pKa = 9.54 SFKK95 pKa = 10.23 EE96 pKa = 4.26 DD97 pKa = 3.15 NLCFYY102 pKa = 10.87 VYY104 pKa = 10.31 EE105 pKa = 4.31 LSEE108 pKa = 4.06 CALNIFNRR116 pKa = 11.84 RR117 pKa = 11.84 NLLLRR122 pKa = 11.84 NLNSFDD128 pKa = 3.59 DD129 pKa = 4.06 TLLLRR134 pKa = 11.84 TKK136 pKa = 10.36 KK137 pKa = 9.72 YY138 pKa = 10.58 QRR140 pKa = 11.84 LSKK143 pKa = 10.62 YY144 pKa = 10.77 NEE146 pKa = 3.77 ILRR149 pKa = 11.84 SIVSQMLYY157 pKa = 9.96 AFEE160 pKa = 4.41 VIKK163 pKa = 10.88 VASKK167 pKa = 10.37 YY168 pKa = 10.88 EE169 pKa = 4.03 KK170 pKa = 10.72 VQLNLYY176 pKa = 5.68 WTKK179 pKa = 10.85 AQQNLNEE186 pKa = 4.14 IMEE189 pKa = 4.53 HH190 pKa = 5.26 NKK192 pKa = 9.76 IPIEE196 pKa = 4.0 PAAIPPARR204 pKa = 11.84 RR205 pKa = 11.84 RR206 pKa = 11.84 YY207 pKa = 9.13 RR208 pKa = 11.84 LEE210 pKa = 3.34 RR211 pKa = 11.84 HH212 pKa = 5.34 EE213 pKa = 5.88 FITEE217 pKa = 4.05 PEE219 pKa = 4.18 PFAPIYY225 pKa = 9.9 QEE227 pKa = 4.0 PSRR230 pKa = 11.84 SRR232 pKa = 11.84 QMQRR236 pKa = 11.84 EE237 pKa = 4.34 RR238 pKa = 11.84 ISGPMTVRR246 pKa = 11.84 LQEE249 pKa = 3.63 ILRR252 pKa = 11.84 RR253 pKa = 11.84 KK254 pKa = 8.71 VKK256 pKa = 10.61 KK257 pKa = 10.11 LVKK260 pKa = 9.21 KK261 pKa = 5.07 TTKK264 pKa = 10.15 GVQIQEE270 pKa = 4.35 DD271 pKa = 4.03 LQKK274 pKa = 10.04 VTFSKK279 pKa = 10.41 KK280 pKa = 10.16 GKK282 pKa = 9.97 DD283 pKa = 3.55 LIFEE287 pKa = 4.52 KK288 pKa = 10.91 DD289 pKa = 3.89 DD290 pKa = 3.53 INYY293 pKa = 8.69 HH294 pKa = 5.58 QIVKK298 pKa = 9.88 EE299 pKa = 3.9 FNIQDD304 pKa = 3.55 EE305 pKa = 4.65 TSQISSSVLKK315 pKa = 10.5 NVRR318 pKa = 11.84 DD319 pKa = 3.71 YY320 pKa = 11.19 FVNNTNVGQMLTKK333 pKa = 10.49 SEE335 pKa = 4.06 WASIALAVIQIIVNVVQSLTGGKK358 pKa = 9.87 LFLSILGCVAAVGQIIISIIRR379 pKa = 11.84 LAGFGVIDD387 pKa = 4.29 VDD389 pKa = 3.19 IDD391 pKa = 3.5 KK392 pKa = 11.16 LNEE395 pKa = 3.81 HH396 pKa = 6.77 LASYY400 pKa = 10.42 IKK402 pKa = 10.76 AKK404 pKa = 10.5 VEE406 pKa = 4.7 SIVSPDD412 pKa = 3.45 DD413 pKa = 3.83 CLPDD417 pKa = 3.32 TDD419 pKa = 4.75 AEE421 pKa = 4.17 IIEE424 pKa = 5.08 RR425 pKa = 11.84 IFHH428 pKa = 5.4 TQASNEE434 pKa = 3.84 NFQEE438 pKa = 4.2 KK439 pKa = 8.2 FTQEE443 pKa = 3.56 RR444 pKa = 11.84 TDD446 pKa = 3.42 VKK448 pKa = 10.66 KK449 pKa = 10.38 KK450 pKa = 10.74 KK451 pKa = 10.73 NMINEE456 pKa = 4.96 IIPLQEE462 pKa = 4.78 HH463 pKa = 6.21 IVHH466 pKa = 6.6 EE467 pKa = 4.43 NAVSPWHH474 pKa = 6.45 SLFAKK479 pKa = 10.09 ISEE482 pKa = 4.23 INFQNIIKK490 pKa = 10.41 DD491 pKa = 3.54 KK492 pKa = 9.51 TFKK495 pKa = 10.77 IPIIKK500 pKa = 9.98 SLRR503 pKa = 11.84 TSQDD507 pKa = 2.52 NYY509 pKa = 11.01 LCLHH513 pKa = 6.01 HH514 pKa = 7.1 AIWGKK519 pKa = 7.54 RR520 pKa = 11.84 QKK522 pKa = 10.79 DD523 pKa = 3.65 GEE525 pKa = 4.24 VRR527 pKa = 11.84 MSEE530 pKa = 4.02 RR531 pKa = 11.84 QVFTLDD537 pKa = 3.34 QIKK540 pKa = 10.59 VYY542 pKa = 8.66 PTDD545 pKa = 3.41 KK546 pKa = 11.22 AQILLMADD554 pKa = 3.9 NIDD557 pKa = 4.13 APTKK561 pKa = 10.71 DD562 pKa = 3.19 EE563 pKa = 4.04 EE564 pKa = 4.89 VYY566 pKa = 10.96 DD567 pKa = 4.13 KK568 pKa = 11.3 LLEE571 pKa = 4.05 YY572 pKa = 11.23 VNADD576 pKa = 3.22 GFKK579 pKa = 10.83 LMEE582 pKa = 4.33 VCDD585 pKa = 4.9 LYY587 pKa = 11.32 ATILNKK593 pKa = 10.47 DD594 pKa = 3.74 IIILNTDD601 pKa = 3.53 LTVKK605 pKa = 8.52 QTYY608 pKa = 9.14 RR609 pKa = 11.84 VPKK612 pKa = 8.24 PTDD615 pKa = 3.23 TIFLKK620 pKa = 10.88 FEE622 pKa = 4.29 INHH625 pKa = 6.04 FEE627 pKa = 3.92 RR628 pKa = 11.84 VIFDD632 pKa = 3.67 TFKK635 pKa = 11.02 QKK637 pKa = 9.66 YY638 pKa = 7.24 TDD640 pKa = 3.49 NDD642 pKa = 3.66 SFLQTLKK649 pKa = 11.1 LINNWFYY656 pKa = 10.87 RR657 pKa = 11.84 IDD659 pKa = 3.64 MEE661 pKa = 5.68 LVSEE665 pKa = 4.9 LNIEE669 pKa = 4.35 VQKK672 pKa = 10.89 HH673 pKa = 3.8 FRR675 pKa = 11.84 NLHH678 pKa = 5.11 FALINDD684 pKa = 4.43 YY685 pKa = 11.5 NNMAIGGFSVQSFSYY700 pKa = 9.56 RR701 pKa = 11.84 TMSPANIAKK710 pKa = 9.92 YY711 pKa = 8.84 ATTSGISMLSVIIALTTMFCDD732 pKa = 3.52 PKK734 pKa = 9.97 MQVEE738 pKa = 4.47 GTTNKK743 pKa = 9.02 MLKK746 pKa = 10.02 FFSLTRR752 pKa = 11.84 SSKK755 pKa = 10.78 AEE757 pKa = 3.51 MRR759 pKa = 11.84 EE760 pKa = 3.85 NVDD763 pKa = 4.69 LISEE767 pKa = 4.31 FMADD771 pKa = 3.06 MFGIYY776 pKa = 8.41 ITPQTINYY784 pKa = 9.77 SLIADD789 pKa = 4.14 MCEE792 pKa = 3.67 KK793 pKa = 9.81 MQDD796 pKa = 3.74 YY797 pKa = 10.95 VDD799 pKa = 4.39 EE800 pKa = 4.81 EE801 pKa = 4.21 NTTYY805 pKa = 11.17 LEE807 pKa = 4.42 NIKK810 pKa = 10.46 KK811 pKa = 9.68 FYY813 pKa = 9.77 EE814 pKa = 4.03 VKK816 pKa = 10.64 SYY818 pKa = 11.62 VEE820 pKa = 4.01 YY821 pKa = 10.69 CKK823 pKa = 10.64 KK824 pKa = 9.89 QLIMFKK830 pKa = 10.2 TSTKK834 pKa = 10.27 DD835 pKa = 3.08 QTHH838 pKa = 6.55 GYY840 pKa = 9.89 VNAKK844 pKa = 9.19 EE845 pKa = 3.94 QLTGLISKK853 pKa = 9.26 MEE855 pKa = 4.13 TKK857 pKa = 10.56 LNSILSVYY865 pKa = 8.45 KK866 pKa = 10.13 TSAVRR871 pKa = 11.84 QEE873 pKa = 4.09 TLPVRR878 pKa = 11.84 IYY880 pKa = 10.84 GAAGAGKK887 pKa = 7.9 TEE889 pKa = 4.31 FVSKK893 pKa = 10.68 HH894 pKa = 4.72 LVRR897 pKa = 11.84 LVAEE901 pKa = 4.25 NLQIEE906 pKa = 4.59 PSVSTINFGDD916 pKa = 3.5 NKK918 pKa = 10.24 FYY920 pKa = 10.65 PVLNGEE926 pKa = 4.12 NFMIYY931 pKa = 10.54 DD932 pKa = 3.58 EE933 pKa = 4.48 FLARR937 pKa = 11.84 RR938 pKa = 11.84 HH939 pKa = 6.05 EE940 pKa = 4.19 DD941 pKa = 3.87 PILGDD946 pKa = 3.48 FNGIHH951 pKa = 6.34 SSVVFLMDD959 pKa = 3.14 SAEE962 pKa = 4.25 VMFKK966 pKa = 10.69 AQPTPFVCSFLLSNSAYY983 pKa = 9.46 TDD985 pKa = 3.4 LSKK988 pKa = 11.13 KK989 pKa = 10.48 LEE991 pKa = 4.31 CEE993 pKa = 3.87 AEE995 pKa = 3.89 KK996 pKa = 11.08 GFWSRR1001 pKa = 11.84 LEE1003 pKa = 5.39 DD1004 pKa = 3.13 IHH1006 pKa = 6.72 FCNVKK1011 pKa = 10.05 QEE1013 pKa = 4.13 QSHH1016 pKa = 5.69 TRR1018 pKa = 11.84 DD1019 pKa = 3.22 QIPRR1023 pKa = 11.84 GNFDD1027 pKa = 4.66 DD1028 pKa = 4.21 FTHH1031 pKa = 6.29 YY1032 pKa = 10.52 EE1033 pKa = 3.91 YY1034 pKa = 10.72 RR1035 pKa = 11.84 QYY1037 pKa = 8.49 TTTTGKK1043 pKa = 9.69 HH1044 pKa = 5.26 RR1045 pKa = 11.84 NNPVICKK1052 pKa = 7.17 PTPNLRR1058 pKa = 11.84 QHH1060 pKa = 6.15 YY1061 pKa = 10.11 NEE1063 pKa = 5.01 EE1064 pKa = 3.82 EE1065 pKa = 4.25 DD1066 pKa = 4.94 KK1067 pKa = 11.24 FDD1069 pKa = 3.58 DD1070 pKa = 4.53 TIYY1073 pKa = 10.88 GAGDD1077 pKa = 3.25 NMYY1080 pKa = 10.81 KK1081 pKa = 10.37 VLTLKK1086 pKa = 10.79 QIVEE1090 pKa = 4.41 NISAKK1095 pKa = 9.77 IKK1097 pKa = 10.62 KK1098 pKa = 9.49 FEE1100 pKa = 4.41 KK1101 pKa = 9.9 KK1102 pKa = 9.92 FKK1104 pKa = 10.05 NARR1107 pKa = 11.84 SFNLKK1112 pKa = 10.34 SKK1114 pKa = 10.42 IVALKK1119 pKa = 10.47 AKK1121 pKa = 8.29 KK1122 pKa = 8.99 TNITDD1127 pKa = 3.56 QQITEE1132 pKa = 4.07 HH1133 pKa = 6.73 FKK1135 pKa = 10.19 DD1136 pKa = 3.14 QGYY1139 pKa = 10.37 SRR1141 pKa = 11.84 IEE1143 pKa = 4.18 VMQHH1147 pKa = 4.27 LHH1149 pKa = 5.19 QGKK1152 pKa = 8.37 FQTQEE1157 pKa = 3.78 MINFLNSPRR1166 pKa = 11.84 FKK1168 pKa = 11.07 QEE1170 pKa = 2.78 IDD1172 pKa = 3.38 TIAIQDD1178 pKa = 3.47 QMQDD1182 pKa = 2.96 VTQNEE1187 pKa = 4.54 TLDD1190 pKa = 3.69 HH1191 pKa = 5.98 FVVNIKK1197 pKa = 10.86 GPGGTGKK1204 pKa = 7.49 TTIARR1209 pKa = 11.84 KK1210 pKa = 9.12 AATNLKK1216 pKa = 10.37 LMLGMPLVEE1225 pKa = 4.98 FNYY1228 pKa = 10.56 LDD1230 pKa = 3.76 RR1231 pKa = 11.84 EE1232 pKa = 4.37 SAKK1235 pKa = 10.87 SITKK1239 pKa = 9.72 PSIIILNDD1247 pKa = 3.34 CVYY1250 pKa = 11.29 DD1251 pKa = 3.48 EE1252 pKa = 5.02 LMYY1255 pKa = 10.82 INFYY1259 pKa = 11.26 DD1260 pKa = 4.5 SLPKK1264 pKa = 10.36 ACIIFVTHH1272 pKa = 6.44 NLVLNRR1278 pKa = 11.84 DD1279 pKa = 3.74 VVNVQNNLTNNNPVFEE1295 pKa = 4.42 YY1296 pKa = 11.04 LNTQDD1301 pKa = 5.49 DD1302 pKa = 4.98 SYY1304 pKa = 11.68 FPKK1307 pKa = 10.27 RR1308 pKa = 11.84 WFNNAIRR1315 pKa = 11.84 WYY1317 pKa = 8.37 GTQPRR1322 pKa = 11.84 APVWTVDD1329 pKa = 3.53 SQAKK1333 pKa = 7.67 MQINGFPRR1341 pKa = 11.84 RR1342 pKa = 11.84 LGLFGMHH1349 pKa = 5.91 MHH1351 pKa = 7.09 GGMISKK1357 pKa = 10.37 RR1358 pKa = 11.84 SISSCQMYY1366 pKa = 8.46 NTISGFRR1373 pKa = 11.84 VFKK1376 pKa = 10.61 IKK1378 pKa = 10.68 EE1379 pKa = 3.71 KK1380 pKa = 10.67 GDD1382 pKa = 3.5 RR1383 pKa = 11.84 KK1384 pKa = 9.74 GTLDD1388 pKa = 3.61 YY1389 pKa = 11.55 EE1390 pKa = 4.86 GVTEE1394 pKa = 4.94 SEE1396 pKa = 4.73 IISDD1400 pKa = 4.05 IYY1402 pKa = 11.56 SKK1404 pKa = 10.84 FNSYY1408 pKa = 9.87 CKK1410 pKa = 9.38 HH1411 pKa = 5.51 WKK1413 pKa = 9.44 IADD1416 pKa = 3.46 IKK1418 pKa = 10.66 KK1419 pKa = 10.56 LNSQLIDD1426 pKa = 3.46 EE1427 pKa = 6.16 LITQNSQDD1435 pKa = 3.49 IDD1437 pKa = 3.62 ILICAPSAEE1446 pKa = 4.37 DD1447 pKa = 5.26 LIKK1450 pKa = 10.23 FTNNPSALVKK1460 pKa = 9.5 TWAIPISTVSSGFTVKK1476 pKa = 7.98 TTSRR1480 pKa = 11.84 VNNCTFNFDD1489 pKa = 3.61 PTEE1492 pKa = 3.69 FAIPKK1497 pKa = 9.58 NSKK1500 pKa = 8.58 PDD1502 pKa = 2.99 QYY1504 pKa = 10.93 MAVARR1509 pKa = 11.84 NMYY1512 pKa = 9.8 RR1513 pKa = 11.84 IVMQGNVDD1521 pKa = 3.79 FTVIVKK1527 pKa = 10.7 AGDD1530 pKa = 3.56 FKK1532 pKa = 11.3 AICKK1536 pKa = 10.38 NGVINYY1542 pKa = 9.38 CSDD1545 pKa = 3.68 YY1546 pKa = 10.87 EE1547 pKa = 4.14 PEE1549 pKa = 4.04 EE1550 pKa = 3.93 TAFTHH1555 pKa = 6.46 TIVDD1559 pKa = 3.29 KK1560 pKa = 11.05 HH1561 pKa = 4.98 ITIQFTHH1568 pKa = 6.71 EE1569 pKa = 3.79 NTEE1572 pKa = 4.07 RR1573 pKa = 11.84 NLITNIHH1580 pKa = 6.42 LKK1582 pKa = 10.75 DD1583 pKa = 3.77 FAQIVHH1589 pKa = 6.33 NGIPPEE1595 pKa = 4.07 EE1596 pKa = 4.87 YY1597 pKa = 9.19 ITDD1600 pKa = 3.44 ITFDD1604 pKa = 3.56 HH1605 pKa = 6.84 YY1606 pKa = 11.95 LMFLNYY1612 pKa = 9.42 INNISTTEE1620 pKa = 3.99 SEE1622 pKa = 4.09 IVNYY1626 pKa = 9.26 MRR1628 pKa = 11.84 LLDD1631 pKa = 3.73 VKK1633 pKa = 10.83 QSVKK1637 pKa = 10.37 LAEE1640 pKa = 4.18 IQEE1643 pKa = 4.24 KK1644 pKa = 10.71 LGFVRR1649 pKa = 11.84 YY1650 pKa = 9.11 FKK1652 pKa = 10.89 YY1653 pKa = 10.81 FEE1655 pKa = 4.02 STSIYY1660 pKa = 10.18 KK1661 pKa = 10.56 FIMVLFGLATGVMFAFLINMLIKK1684 pKa = 9.81 MVWGSKK1690 pKa = 10.0 KK1691 pKa = 9.27 KK1692 pKa = 7.2 TTQLEE1697 pKa = 4.58 YY1698 pKa = 10.35 KK1699 pKa = 9.17 GHH1701 pKa = 6.77 KK1702 pKa = 9.01 IDD1704 pKa = 6.28 LVFDD1708 pKa = 3.81 WKK1710 pKa = 10.81 LNKK1713 pKa = 10.35 RR1714 pKa = 11.84 IDD1716 pKa = 3.76 DD1717 pKa = 3.84 RR1718 pKa = 11.84 ADD1720 pKa = 3.4 NLVCDD1725 pKa = 4.52 VACDD1729 pKa = 3.59 VLNYY1733 pKa = 10.3 KK1734 pKa = 10.45 DD1735 pKa = 4.77 DD1736 pKa = 5.08 LINFRR1741 pKa = 11.84 EE1742 pKa = 4.31 LKK1744 pKa = 10.59 NLIIQRR1750 pKa = 11.84 IKK1752 pKa = 10.95 FNLIDD1757 pKa = 3.59 NGFIKK1762 pKa = 10.59 SDD1764 pKa = 3.63 TCVEE1768 pKa = 4.19 LSNINIQSCKK1778 pKa = 6.06 EE1779 pKa = 4.2 TKK1781 pKa = 9.77 VLKK1784 pKa = 9.14 TKK1786 pKa = 10.29 PVEE1789 pKa = 4.1 TSNLTKK1795 pKa = 10.58 VEE1797 pKa = 4.11 GKK1799 pKa = 9.6 EE1800 pKa = 3.8 KK1801 pKa = 10.91 SSMYY1805 pKa = 10.72 DD1806 pKa = 3.13 KK1807 pKa = 10.52 QQKK1810 pKa = 9.41 NIKK1813 pKa = 9.85 LKK1815 pKa = 10.01 TKK1817 pKa = 10.28 EE1818 pKa = 3.77 ADD1820 pKa = 3.06 ALQAVLDD1827 pKa = 4.25 KK1828 pKa = 11.02 PSILSKK1834 pKa = 10.6 IEE1836 pKa = 3.82 NNLVKK1841 pKa = 10.8 VKK1843 pKa = 8.45 TTMGDD1848 pKa = 3.48 GLSKK1852 pKa = 10.55 SLYY1855 pKa = 10.73 GLDD1858 pKa = 3.34 IGNGVIITMYY1868 pKa = 10.94 HH1869 pKa = 5.7 NLCLVNTNSNKK1880 pKa = 9.9 YY1881 pKa = 9.78 EE1882 pKa = 4.17 EE1883 pKa = 4.84 ADD1885 pKa = 3.42 HH1886 pKa = 6.39 VQTTVKK1892 pKa = 10.79 YY1893 pKa = 10.24 LVTDD1897 pKa = 3.41 EE1898 pKa = 4.22 EE1899 pKa = 5.13 FEE1901 pKa = 4.54 VKK1903 pKa = 10.11 PVMKK1907 pKa = 10.32 DD1908 pKa = 3.18 PYY1910 pKa = 9.55 HH1911 pKa = 7.31 DD1912 pKa = 3.17 IVIFQIQNRR1921 pKa = 11.84 NGYY1924 pKa = 7.46 NARR1927 pKa = 11.84 ANLIKK1932 pKa = 10.9 YY1933 pKa = 7.56 FIRR1936 pKa = 11.84 DD1937 pKa = 3.41 KK1938 pKa = 11.34 NRR1940 pKa = 11.84 TKK1942 pKa = 9.98 HH1943 pKa = 5.43 TMSEE1947 pKa = 4.23 MYY1949 pKa = 10.1 TYY1951 pKa = 11.41 DD1952 pKa = 3.48 RR1953 pKa = 11.84 VKK1955 pKa = 11.27 NNNNGLNRR1963 pKa = 11.84 TKK1965 pKa = 10.89 LVGTTANIQLVKK1977 pKa = 10.4 DD1978 pKa = 3.87 TVNLTKK1984 pKa = 10.64 GAFVYY1989 pKa = 8.37 VTSVLFCYY1997 pKa = 10.32 GMATKK2002 pKa = 10.35 EE2003 pKa = 4.17 GDD2005 pKa = 3.64 CGLPLYY2011 pKa = 10.54 ALNDD2015 pKa = 3.46 SHH2017 pKa = 7.4 EE2018 pKa = 4.43 ILCGLHH2024 pKa = 5.8 YY2025 pKa = 10.64 GGNASHH2031 pKa = 7.12 IGAVQITQEE2040 pKa = 4.09 YY2041 pKa = 9.99 LEE2043 pKa = 4.44 TVYY2046 pKa = 10.94 SQIMEE2051 pKa = 4.18 IEE2053 pKa = 4.22 DD2054 pKa = 3.79 EE2055 pKa = 4.39 EE2056 pKa = 4.83 FFDD2059 pKa = 4.69 AVEE2062 pKa = 4.49 IEE2064 pKa = 4.03 LDD2066 pKa = 3.65 QNEE2069 pKa = 5.07 LEE2071 pKa = 4.54 DD2072 pKa = 3.42 EE2073 pKa = 4.73 TYY2075 pKa = 11.02 FEE2077 pKa = 4.29 FTEE2080 pKa = 4.38 VTFDD2084 pKa = 3.54 AFGKK2088 pKa = 10.48 EE2089 pKa = 3.93 EE2090 pKa = 4.21 TVVLDD2095 pKa = 3.5 NHH2097 pKa = 6.56 SLSILQDD2104 pKa = 3.31 CDD2106 pKa = 3.96 LGSKK2110 pKa = 7.58 QTFEE2114 pKa = 4.12 CLEE2117 pKa = 4.07 VGEE2120 pKa = 4.2 NTEE2123 pKa = 4.11 PFGYY2127 pKa = 5.99 THH2129 pKa = 6.98 KK2130 pKa = 10.56 GARR2133 pKa = 11.84 AFRR2136 pKa = 11.84 LKK2138 pKa = 10.37 SKK2140 pKa = 10.13 YY2141 pKa = 10.04 IPTPYY2146 pKa = 9.53 TDD2148 pKa = 5.04 EE2149 pKa = 4.3 IDD2151 pKa = 3.42 EE2152 pKa = 4.85 RR2153 pKa = 11.84 IPRR2156 pKa = 11.84 EE2157 pKa = 4.05 EE2158 pKa = 4.13 MNSATSNKK2166 pKa = 9.47 KK2167 pKa = 10.25 VEE2169 pKa = 4.69 DD2170 pKa = 4.04 PSNLPVNRR2178 pKa = 11.84 RR2179 pKa = 11.84 GEE2181 pKa = 3.87 PSILIGQQDD2190 pKa = 4.05 KK2191 pKa = 11.65 LNDD2194 pKa = 3.7 PVDD2197 pKa = 3.87 ALGKK2201 pKa = 10.32 SLGDD2205 pKa = 3.34 KK2206 pKa = 10.34 YY2207 pKa = 10.85 LARR2210 pKa = 11.84 ALEE2213 pKa = 3.93 ILIPHH2218 pKa = 5.79 YY2219 pKa = 10.37 KK2220 pKa = 9.89 KK2221 pKa = 10.55 LYY2223 pKa = 10.08 GRR2225 pKa = 11.84 FKK2227 pKa = 10.93 HH2228 pKa = 5.78 RR2229 pKa = 11.84 TLTDD2233 pKa = 3.48 LEE2235 pKa = 4.88 VINGTYY2241 pKa = 10.11 INPRR2245 pKa = 11.84 CPSFQNLEE2253 pKa = 4.45 PIDD2256 pKa = 3.67 RR2257 pKa = 11.84 TGSIGYY2263 pKa = 9.62 DD2264 pKa = 3.31 VTSVFHH2270 pKa = 6.43 IQHH2273 pKa = 6.38 KK2274 pKa = 10.8 NDD2276 pKa = 3.13 VLKK2279 pKa = 10.95 LFKK2282 pKa = 10.04 TLPCGRR2288 pKa = 11.84 HH2289 pKa = 5.29 IYY2291 pKa = 10.14 HH2292 pKa = 6.55 YY2293 pKa = 10.89 ADD2295 pKa = 3.49 TEE2297 pKa = 3.72 AARR2300 pKa = 11.84 YY2301 pKa = 8.83 VRR2303 pKa = 11.84 RR2304 pKa = 11.84 QEE2306 pKa = 4.18 EE2307 pKa = 4.49 VTLHH2311 pKa = 5.61 YY2312 pKa = 10.02 WEE2314 pKa = 3.81 QDD2316 pKa = 3.09 KK2317 pKa = 11.17 RR2318 pKa = 11.84 CEE2320 pKa = 4.38 SLVQSNLKK2328 pKa = 10.68 CEE2330 pKa = 4.06 LRR2332 pKa = 11.84 PLEE2335 pKa = 4.13 KK2336 pKa = 10.75 VRR2338 pKa = 11.84 VGKK2341 pKa = 7.62 TRR2343 pKa = 11.84 CFEE2346 pKa = 4.24 SFTMANSNATRR2357 pKa = 11.84 RR2358 pKa = 11.84 ILGTLFAAIKK2368 pKa = 8.95 MYY2370 pKa = 10.36 RR2371 pKa = 11.84 SEE2373 pKa = 4.47 GFAQVGIDD2381 pKa = 3.26 TVNFQQLYY2389 pKa = 10.51 EE2390 pKa = 4.08 RR2391 pKa = 11.84 FQRR2394 pKa = 11.84 LGQFGEE2400 pKa = 4.49 AGDD2403 pKa = 4.02 FSAWDD2408 pKa = 3.36 KK2409 pKa = 11.51 HH2410 pKa = 6.23 LMPNAIEE2417 pKa = 4.5 LVTDD2421 pKa = 3.94 LWTEE2425 pKa = 3.84 TFFASWEE2432 pKa = 4.34 EE2433 pKa = 3.58 VDD2435 pKa = 3.07 PTYY2438 pKa = 10.52 RR2439 pKa = 11.84 IKK2441 pKa = 10.46 IRR2443 pKa = 11.84 NQIHH2447 pKa = 5.99 QILVSNYY2454 pKa = 8.82 KK2455 pKa = 10.52 AIIIADD2461 pKa = 3.53 GNVFTKK2467 pKa = 10.56 QRR2469 pKa = 11.84 GNCSGAQTTTHH2480 pKa = 6.7 LNGSVNDD2487 pKa = 4.56 LYY2489 pKa = 10.96 RR2490 pKa = 11.84 VACILYY2496 pKa = 10.66 LIDD2499 pKa = 3.38 QHH2501 pKa = 6.4 NAHH2504 pKa = 6.77 CEE2506 pKa = 3.6 ISPKK2510 pKa = 10.42 SEE2512 pKa = 3.43 IKK2514 pKa = 10.07 EE2515 pKa = 4.04 KK2516 pKa = 11.08 YY2517 pKa = 7.88 EE2518 pKa = 3.58 QIPFIEE2524 pKa = 5.07 RR2525 pKa = 11.84 YY2526 pKa = 6.73 TRR2528 pKa = 11.84 QMQLDD2533 pKa = 3.66 KK2534 pKa = 11.84 VEE2536 pKa = 4.25 INSMEE2541 pKa = 5.67 DD2542 pKa = 2.78 ILKK2545 pKa = 8.59 ITDD2548 pKa = 3.06 WVDD2551 pKa = 3.17 YY2552 pKa = 10.94 GDD2554 pKa = 5.33 DD2555 pKa = 3.64 LASVINLNYY2564 pKa = 10.23 VNILNFVSFKK2574 pKa = 9.94 MAYY2577 pKa = 9.68 NYY2579 pKa = 10.75 LFGITYY2585 pKa = 9.27 DD2586 pKa = 3.75 SPAKK2590 pKa = 10.38 DD2591 pKa = 3.38 GSIALLTPLIKK2602 pKa = 10.65 LSFISRR2608 pKa = 11.84 TFHH2611 pKa = 7.74 LDD2613 pKa = 2.94 EE2614 pKa = 4.77 NLNIITPRR2622 pKa = 11.84 LKK2624 pKa = 10.51 LSSINRR2630 pKa = 11.84 LLHH2633 pKa = 4.96 WTTSIDD2639 pKa = 3.52 PDD2641 pKa = 3.6 QLKK2644 pKa = 9.85 TNLDD2648 pKa = 3.98 EE2649 pKa = 6.07 IFDD2652 pKa = 3.86 EE2653 pKa = 4.71 LKK2655 pKa = 10.75 FYY2657 pKa = 10.97 DD2658 pKa = 3.43 SSLYY2662 pKa = 10.35 SSYY2665 pKa = 10.83 IRR2667 pKa = 11.84 IVKK2670 pKa = 9.56 EE2671 pKa = 3.49 IINPYY2676 pKa = 9.22 LLKK2679 pKa = 10.53 NYY2681 pKa = 7.41 RR2682 pKa = 11.84 TAYY2685 pKa = 10.28 SPPNYY2690 pKa = 9.61 HH2691 pKa = 7.26 LLRR2694 pKa = 11.84 GHH2696 pKa = 6.21 YY2697 pKa = 9.54 EE2698 pKa = 3.91 NAVKK2702 pKa = 10.42 NVRR2705 pKa = 11.84 KK2706 pKa = 9.23 EE2707 pKa = 3.39 QDD2709 pKa = 2.96 AYY2711 pKa = 10.16 IDD2713 pKa = 3.27 ASLRR2717 pKa = 11.84 INEE2720 pKa = 4.19 KK2721 pKa = 10.94 NKK2723 pKa = 9.97 ILEE2726 pKa = 4.15 NFQRR2730 pKa = 11.84 IIDD2733 pKa = 4.19 LFATQGTQLTRR2744 pKa = 11.84 RR2745 pKa = 11.84 IPDD2748 pKa = 3.49 LEE2750 pKa = 4.39 TNLLSEE2756 pKa = 4.21 NMTPEE2761 pKa = 4.15 TIKK2764 pKa = 10.76 EE2765 pKa = 4.11 YY2766 pKa = 10.92 FEE2768 pKa = 4.75 SLFIRR2773 pKa = 11.84 MRR2775 pKa = 11.84 VNTQLKK2781 pKa = 10.31 ISGLPAKK2788 pKa = 9.4 VTAEE2792 pKa = 3.77 NGAVFWSISCEE2803 pKa = 3.91 PLYY2806 pKa = 10.27 DD2807 pKa = 3.74 TSLKK2811 pKa = 10.34 EE2812 pKa = 3.93 YY2813 pKa = 10.55 RR2814 pKa = 11.84 KK2815 pKa = 9.97 DD2816 pKa = 3.29 LQRR2819 pKa = 11.84 ILQSSRR2825 pKa = 11.84 HH2826 pKa = 4.18 FTFVTVEE2833 pKa = 4.03 DD2834 pKa = 4.08 LEE2836 pKa = 4.75 IYY2838 pKa = 10.13 IPNPLKK2844 pKa = 10.56 RR2845 pKa = 11.84 IQFRR2849 pKa = 11.84 VIQRR2853 pKa = 11.84 GEE2855 pKa = 4.14 SVGKK2859 pKa = 9.64 EE2860 pKa = 3.81 FSVHH2864 pKa = 5.31 EE2865 pKa = 4.16 LRR2867 pKa = 11.84 DD2868 pKa = 3.51 ALFNIQAATSAAMVDD2883 pKa = 3.9 PMPKK2887 pKa = 8.4 VTPGAPVPLQDD2898 pKa = 3.45 SGLPVGLHH2906 pKa = 5.34 QLGFSQKK2913 pKa = 7.95 STAMLAYY2920 pKa = 9.73 EE2921 pKa = 4.22 YY2922 pKa = 11.1 APLANYY2928 pKa = 7.7 TIPVGSTSGKK2938 pKa = 10.39 VILNLTRR2945 pKa = 11.84 TDD2947 pKa = 3.57 LVNEE2951 pKa = 4.28 FMRR2954 pKa = 11.84 ACKK2957 pKa = 10.02 TGDD2960 pKa = 2.93 SYY2962 pKa = 12.14 YY2963 pKa = 11.1 NGSFKK2968 pKa = 11.16 VKK2970 pKa = 10.15 FVSQTNPGLTGTLLIGMTRR2989 pKa = 11.84 SKK2991 pKa = 10.83 LDD2993 pKa = 3.42 SPTEE2997 pKa = 3.54 TDD2999 pKa = 3.31 MLIKK3003 pKa = 9.29 QTYY3006 pKa = 9.04 QIDD3009 pKa = 4.21 GNSSQNFEE3017 pKa = 4.23 LTISPFTDD3025 pKa = 3.1 DD3026 pKa = 3.12 VVKK3029 pKa = 10.87 ARR3031 pKa = 11.84 FAWPPSEE3038 pKa = 5.8 ADD3040 pKa = 3.4 DD3041 pKa = 5.0 DD3042 pKa = 4.84 YY3043 pKa = 11.89 YY3044 pKa = 10.45 PALVIIVKK3052 pKa = 10.22 CDD3054 pKa = 3.65 FVSTFDD3060 pKa = 3.73 NPSLYY3065 pKa = 10.73 SQIQLYY3071 pKa = 7.96 TAFSPDD3077 pKa = 2.89 FVTFFNGFPKK3087 pKa = 9.61 NTGYY3091 pKa = 8.17 NTRR3094 pKa = 11.84 DD3095 pKa = 3.31 AQLSINTVIPLDD3107 pKa = 3.98 DD3108 pKa = 3.75 VLGKK3112 pKa = 9.79 DD3113 pKa = 3.36 VRR3115 pKa = 11.84 LFTDD3119 pKa = 4.37 GNLFTPNIIQVTQSQVEE3136 pKa = 4.54 VVASDD3141 pKa = 3.68 TLHH3144 pKa = 5.56 TAEE3147 pKa = 4.7 AFEE3150 pKa = 5.02 IKK3152 pKa = 9.87 DD3153 pKa = 3.37 QKK3155 pKa = 10.88 RR3156 pKa = 11.84 ITRR3159 pKa = 11.84 TWATASGWGSFISYY3173 pKa = 9.89 EE3174 pKa = 3.94 NSLLQLRR3181 pKa = 11.84 NPKK3184 pKa = 10.13 SSTVINSIEE3193 pKa = 3.92 LLIDD3197 pKa = 3.54 YY3198 pKa = 10.97 AEE3200 pKa = 4.96 GPSFTLNSDD3209 pKa = 2.7 VDD3211 pKa = 3.79 INEE3214 pKa = 3.78 KK3215 pKa = 10.38 RR3216 pKa = 11.84 IEE3218 pKa = 3.89 LASIGKK3224 pKa = 9.47 VDD3226 pKa = 4.89 DD3227 pKa = 3.55 RR3228 pKa = 11.84 TNYY3231 pKa = 9.69 MDD3233 pKa = 4.97 IEE3235 pKa = 4.47 FTNVWCKK3242 pKa = 10.71 CYY3244 pKa = 10.62 VSQKK3248 pKa = 10.27 EE3249 pKa = 3.84 RR3250 pKa = 11.84 DD3251 pKa = 3.49 EE3252 pKa = 4.37 KK3253 pKa = 11.12 LDD3255 pKa = 3.7 RR3256 pKa = 11.84 KK3257 pKa = 10.56 NMQTFLKK3264 pKa = 10.22 YY3265 pKa = 9.99 IEE3267 pKa = 4.76 PNFVSDD3273 pKa = 3.38 VTTYY3277 pKa = 10.78 QVLAPLIKK3285 pKa = 10.76 VKK3287 pKa = 10.26 IDD3289 pKa = 3.57 NKK3291 pKa = 10.9 NKK3293 pKa = 9.61 LQSFSVTFDD3302 pKa = 3.06 FTEE3305 pKa = 4.0 LHH3307 pKa = 6.81 DD3308 pKa = 4.21 KK3309 pKa = 11.16 VGTLFTMLSLNADD3322 pKa = 3.42 DD3323 pKa = 5.06 TSFNCLLTSVYY3334 pKa = 10.51 GFNFTLVIPFDD3345 pKa = 4.21 FSKK3348 pKa = 9.84 LTQANLANFPDD3359 pKa = 5.84 AITLPAGASSLQAVKK3374 pKa = 10.67 LPFVVPPASTGAVNAAGSTLLPNISIFDD3402 pKa = 3.86 NLSKK3406 pKa = 11.01 VLATDD3411 pKa = 5.22 KK3412 pKa = 10.57 IYY3414 pKa = 10.75 QLQLTTKK3421 pKa = 10.05 DD3422 pKa = 3.53 YY3423 pKa = 11.3 SDD3425 pKa = 3.92 LVGTFIFHH3433 pKa = 6.39 GPKK3436 pKa = 8.9 RR3437 pKa = 11.84 TCFFNTNKK3445 pKa = 9.69 IEE3447 pKa = 4.07 YY3448 pKa = 9.21 LVSSYY3453 pKa = 10.15 MSQEE3457 pKa = 3.45 LNLRR3461 pKa = 11.84 VNNVISLNAQLPVTKK3476 pKa = 9.76 YY3477 pKa = 9.57 NSSAFVQRR3485 pKa = 11.84 NTKK3488 pKa = 10.06 SLVRR3492 pKa = 11.84 RR3493 pKa = 11.84 EE3494 pKa = 3.85 ISAEE3498 pKa = 3.93 TFNVQGAAASVGAGALMGVGQGLGNYY3524 pKa = 10.49 LNMQQNFQNNKK3535 pKa = 9.44 EE3536 pKa = 4.09 LLLLNQGFNKK3546 pKa = 9.76 EE3547 pKa = 3.98 QAKK3550 pKa = 9.83 MMLEE3554 pKa = 3.93 MQGANQLAAISAYY3567 pKa = 10.51 GEE3569 pKa = 4.15 NQLGALGIKK3578 pKa = 9.45 GANTLNAIAAQGEE3591 pKa = 4.4 NTKK3594 pKa = 10.55 EE3595 pKa = 3.83 QMFLQHH3601 pKa = 6.35 TLNNLNTPGMSVQRR3615 pKa = 11.84 SQNQNFVSGGHH3626 pKa = 5.73 QYY3628 pKa = 11.29 PDD3630 pKa = 3.67 TQNSTTLEE3638 pKa = 4.18 TPIEE3642 pKa = 4.13 QFDD3645 pKa = 3.98 LHH3647 pKa = 6.02 TGARR3651 pKa = 11.84 IKK3653 pKa = 9.24 QTSPIQPTVNSAGDD3667 pKa = 3.73 DD3668 pKa = 3.84 APNTSVDD3675 pKa = 3.71 SLSRR3679 pKa = 11.84 AAIEE3683 pKa = 3.8 NTLFEE3688 pKa = 4.58 EE3689 pKa = 5.56 SYY3691 pKa = 11.03 HH3692 pKa = 7.05 SPTPNKK3698 pKa = 10.39 NPLAGAAGEE3707 pKa = 4.33 VRR3709 pKa = 11.84 DD3710 pKa = 4.0 GMEE3713 pKa = 4.3 NLVDD3717 pKa = 4.1 TIGDD3721 pKa = 3.66 YY3722 pKa = 9.02 RR3723 pKa = 11.84 TLEE3726 pKa = 4.27 NLNMHH3731 pKa = 6.67 DD3732 pKa = 3.81 TSSTPTQQTRR3742 pKa = 11.84 AMPKK3746 pKa = 9.02 NKK3748 pKa = 9.62 LANSHH3753 pKa = 6.22 GLGADD3758 pKa = 3.39 PGTKK3762 pKa = 9.83 LSQMKK3767 pKa = 9.93 FPGVTTSVSVII3778 pKa = 3.53
Molecular weight: 432.37 kDa
Isoelectric point according different methods:
IPC2.protein.svr19 5.979
IPC2_protein 5.995
IPC_protein 6.059
Toseland 6.389
ProMoST 6.427
Dawson 6.338
Bjellqvist 6.364
Wikipedia 6.351
Rodwell 6.338
Grimsley 6.532
Solomon 6.338
Lehninger 6.338
Nozaki 6.62
DTASelect 6.795
Thurlkill 6.81
EMBOSS 6.781
Sillero 6.722
Patrickios 4.202
IPC_peptide 6.364
IPC2_peptide 6.59
IPC2.peptide.svr19 6.673
Protein with the highest isoelectric point:
>tr|A0A1L3KKW6|A0A1L3KKW6_9VIRU RdRP_1 domain-containing protein OS=Hubei picorna-like virus 52 OX=1923134 PE=4 SV=1
MM1 pKa = 6.42 QTTMVNTMYY10 pKa = 10.05 MIKK13 pKa = 10.33 AKK15 pKa = 8.68 QFKK18 pKa = 8.72 RR19 pKa = 11.84 QHH21 pKa = 5.61 RR22 pKa = 11.84 VLVEE26 pKa = 3.77 EE27 pKa = 4.58 QILKK31 pKa = 10.48 EE32 pKa = 4.44 DD33 pKa = 4.46 LDD35 pKa = 3.95 FQPRR39 pKa = 11.84 EE40 pKa = 3.92 PRR42 pKa = 11.84 QLFSNVEE49 pKa = 4.31 YY50 pKa = 10.24 IWEE53 pKa = 4.2 CFPNYY58 pKa = 9.36 EE59 pKa = 4.69 HH60 pKa = 7.51 INYY63 pKa = 10.15 SLFKK67 pKa = 10.51 RR68 pKa = 11.84 DD69 pKa = 3.11 VDD71 pKa = 3.63 EE72 pKa = 5.58 LKK74 pKa = 10.6 ILLRR78 pKa = 11.84 SIQRR82 pKa = 11.84 QFNIYY87 pKa = 8.98 EE88 pKa = 4.21 RR89 pKa = 11.84 NSKK92 pKa = 9.54 SFKK95 pKa = 10.23 EE96 pKa = 4.26 DD97 pKa = 3.15 NLCFYY102 pKa = 10.87 VYY104 pKa = 10.31 EE105 pKa = 4.31 LSEE108 pKa = 4.06 CALNIFNRR116 pKa = 11.84 RR117 pKa = 11.84 NLLLRR122 pKa = 11.84 NLNSFDD128 pKa = 3.59 DD129 pKa = 4.06 TLLLRR134 pKa = 11.84 TKK136 pKa = 10.36 KK137 pKa = 9.72 YY138 pKa = 10.58 QRR140 pKa = 11.84 LSKK143 pKa = 10.62 YY144 pKa = 10.77 NEE146 pKa = 3.77 ILRR149 pKa = 11.84 SIVSQMLYY157 pKa = 9.96 AFEE160 pKa = 4.41 VIKK163 pKa = 10.88 VASKK167 pKa = 10.37 YY168 pKa = 10.88 EE169 pKa = 4.03 KK170 pKa = 10.72 VQLNLYY176 pKa = 5.68 WTKK179 pKa = 10.85 AQQNLNEE186 pKa = 4.14 IMEE189 pKa = 4.53 HH190 pKa = 5.26 NKK192 pKa = 9.76 IPIEE196 pKa = 4.0 PAAIPPARR204 pKa = 11.84 RR205 pKa = 11.84 RR206 pKa = 11.84 YY207 pKa = 9.13 RR208 pKa = 11.84 LEE210 pKa = 3.34 RR211 pKa = 11.84 HH212 pKa = 5.34 EE213 pKa = 5.88 FITEE217 pKa = 4.05 PEE219 pKa = 4.18 PFAPIYY225 pKa = 9.9 QEE227 pKa = 4.0 PSRR230 pKa = 11.84 SRR232 pKa = 11.84 QMQRR236 pKa = 11.84 EE237 pKa = 4.34 RR238 pKa = 11.84 ISGPMTVRR246 pKa = 11.84 LQEE249 pKa = 3.63 ILRR252 pKa = 11.84 RR253 pKa = 11.84 KK254 pKa = 8.71 VKK256 pKa = 10.61 KK257 pKa = 10.11 LVKK260 pKa = 9.21 KK261 pKa = 5.07 TTKK264 pKa = 10.15 GVQIQEE270 pKa = 4.35 DD271 pKa = 4.03 LQKK274 pKa = 10.04 VTFSKK279 pKa = 10.41 KK280 pKa = 10.16 GKK282 pKa = 9.97 DD283 pKa = 3.55 LIFEE287 pKa = 4.52 KK288 pKa = 10.91 DD289 pKa = 3.89 DD290 pKa = 3.53 INYY293 pKa = 8.69 HH294 pKa = 5.58 QIVKK298 pKa = 9.88 EE299 pKa = 3.9 FNIQDD304 pKa = 3.55 EE305 pKa = 4.65 TSQISSSVLKK315 pKa = 10.5 NVRR318 pKa = 11.84 DD319 pKa = 3.71 YY320 pKa = 11.19 FVNNTNVGQMLTKK333 pKa = 10.49 SEE335 pKa = 4.06 WASIALAVIQIIVNVVQSLTGGKK358 pKa = 9.87 LFLSILGCVAAVGQIIISIIRR379 pKa = 11.84 LAGFGVIDD387 pKa = 4.29 VDD389 pKa = 3.19 IDD391 pKa = 3.5 KK392 pKa = 11.16 LNEE395 pKa = 3.81 HH396 pKa = 6.77 LASYY400 pKa = 10.42 IKK402 pKa = 10.76 AKK404 pKa = 10.5 VEE406 pKa = 4.7 SIVSPDD412 pKa = 3.45 DD413 pKa = 3.83 CLPDD417 pKa = 3.32 TDD419 pKa = 4.75 AEE421 pKa = 4.17 IIEE424 pKa = 5.08 RR425 pKa = 11.84 IFHH428 pKa = 5.4 TQASNEE434 pKa = 3.84 NFQEE438 pKa = 4.2 KK439 pKa = 8.2 FTQEE443 pKa = 3.56 RR444 pKa = 11.84 TDD446 pKa = 3.42 VKK448 pKa = 10.66 KK449 pKa = 10.38 KK450 pKa = 10.74 KK451 pKa = 10.73 NMINEE456 pKa = 4.96 IIPLQEE462 pKa = 4.78 HH463 pKa = 6.21 IVHH466 pKa = 6.6 EE467 pKa = 4.43 NAVSPWHH474 pKa = 6.45 SLFAKK479 pKa = 10.09 ISEE482 pKa = 4.23 INFQNIIKK490 pKa = 10.41 DD491 pKa = 3.54 KK492 pKa = 9.51 TFKK495 pKa = 10.77 IPIIKK500 pKa = 9.98 SLRR503 pKa = 11.84 TSQDD507 pKa = 2.52 NYY509 pKa = 11.01 LCLHH513 pKa = 6.01 HH514 pKa = 7.1 AIWGKK519 pKa = 7.54 RR520 pKa = 11.84 QKK522 pKa = 10.79 DD523 pKa = 3.65 GEE525 pKa = 4.24 VRR527 pKa = 11.84 MSEE530 pKa = 4.02 RR531 pKa = 11.84 QVFTLDD537 pKa = 3.34 QIKK540 pKa = 10.59 VYY542 pKa = 8.66 PTDD545 pKa = 3.41 KK546 pKa = 11.22 AQILLMADD554 pKa = 3.9 NIDD557 pKa = 4.13 APTKK561 pKa = 10.71 DD562 pKa = 3.19 EE563 pKa = 4.04 EE564 pKa = 4.89 VYY566 pKa = 10.96 DD567 pKa = 4.13 KK568 pKa = 11.3 LLEE571 pKa = 4.05 YY572 pKa = 11.23 VNADD576 pKa = 3.22 GFKK579 pKa = 10.83 LMEE582 pKa = 4.33 VCDD585 pKa = 4.9 LYY587 pKa = 11.32 ATILNKK593 pKa = 10.47 DD594 pKa = 3.74 IIILNTDD601 pKa = 3.53 LTVKK605 pKa = 8.52 QTYY608 pKa = 9.14 RR609 pKa = 11.84 VPKK612 pKa = 8.24 PTDD615 pKa = 3.23 TIFLKK620 pKa = 10.88 FEE622 pKa = 4.29 INHH625 pKa = 6.04 FEE627 pKa = 3.92 RR628 pKa = 11.84 VIFDD632 pKa = 3.67 TFKK635 pKa = 11.02 QKK637 pKa = 9.66 YY638 pKa = 7.24 TDD640 pKa = 3.49 NDD642 pKa = 3.66 SFLQTLKK649 pKa = 11.1 LINNWFYY656 pKa = 10.87 RR657 pKa = 11.84 IDD659 pKa = 3.64 MEE661 pKa = 5.68 LVSEE665 pKa = 4.9 LNIEE669 pKa = 4.35 VQKK672 pKa = 10.89 HH673 pKa = 3.8 FRR675 pKa = 11.84 NLHH678 pKa = 5.11 FALINDD684 pKa = 4.43 YY685 pKa = 11.5 NNMAIGGFSVQSFSYY700 pKa = 9.56 RR701 pKa = 11.84 TMSPANIAKK710 pKa = 9.92 YY711 pKa = 8.84 ATTSGISMLSVIIALTTMFCDD732 pKa = 3.52 PKK734 pKa = 9.97 MQVEE738 pKa = 4.47 GTTNKK743 pKa = 9.02 MLKK746 pKa = 10.02 FFSLTRR752 pKa = 11.84 SSKK755 pKa = 10.78 AEE757 pKa = 3.51 MRR759 pKa = 11.84 EE760 pKa = 3.85 NVDD763 pKa = 4.69 LISEE767 pKa = 4.31 FMADD771 pKa = 3.06 MFGIYY776 pKa = 8.41 ITPQTINYY784 pKa = 9.77 SLIADD789 pKa = 4.14 MCEE792 pKa = 3.67 KK793 pKa = 9.81 MQDD796 pKa = 3.74 YY797 pKa = 10.95 VDD799 pKa = 4.39 EE800 pKa = 4.81 EE801 pKa = 4.21 NTTYY805 pKa = 11.17 LEE807 pKa = 4.42 NIKK810 pKa = 10.46 KK811 pKa = 9.68 FYY813 pKa = 9.77 EE814 pKa = 4.03 VKK816 pKa = 10.64 SYY818 pKa = 11.62 VEE820 pKa = 4.01 YY821 pKa = 10.69 CKK823 pKa = 10.64 KK824 pKa = 9.89 QLIMFKK830 pKa = 10.2 TSTKK834 pKa = 10.27 DD835 pKa = 3.08 QTHH838 pKa = 6.55 GYY840 pKa = 9.89 VNAKK844 pKa = 9.19 EE845 pKa = 3.94 QLTGLISKK853 pKa = 9.26 MEE855 pKa = 4.13 TKK857 pKa = 10.56 LNSILSVYY865 pKa = 8.45 KK866 pKa = 10.13 TSAVRR871 pKa = 11.84 QEE873 pKa = 4.09 TLPVRR878 pKa = 11.84 IYY880 pKa = 10.84 GAAGAGKK887 pKa = 7.9 TEE889 pKa = 4.31 FVSKK893 pKa = 10.68 HH894 pKa = 4.72 LVRR897 pKa = 11.84 LVAEE901 pKa = 4.25 NLQIEE906 pKa = 4.59 PSVSTINFGDD916 pKa = 3.5 NKK918 pKa = 10.24 FYY920 pKa = 10.65 PVLNGEE926 pKa = 4.12 NFMIYY931 pKa = 10.54 DD932 pKa = 3.58 EE933 pKa = 4.48 FLARR937 pKa = 11.84 RR938 pKa = 11.84 HH939 pKa = 6.05 EE940 pKa = 4.19 DD941 pKa = 3.87 PILGDD946 pKa = 3.48 FNGIHH951 pKa = 6.34 SSVVFLMDD959 pKa = 3.14 SAEE962 pKa = 4.25 VMFKK966 pKa = 10.69 AQPTPFVCSFLLSNSAYY983 pKa = 9.46 TDD985 pKa = 3.4 LSKK988 pKa = 11.13 KK989 pKa = 10.48 LEE991 pKa = 4.31 CEE993 pKa = 3.87 AEE995 pKa = 3.89 KK996 pKa = 11.08 GFWSRR1001 pKa = 11.84 LEE1003 pKa = 5.39 DD1004 pKa = 3.13 IHH1006 pKa = 6.72 FCNVKK1011 pKa = 10.05 QEE1013 pKa = 4.13 QSHH1016 pKa = 5.69 TRR1018 pKa = 11.84 DD1019 pKa = 3.22 QIPRR1023 pKa = 11.84 GNFDD1027 pKa = 4.66 DD1028 pKa = 4.21 FTHH1031 pKa = 6.29 YY1032 pKa = 10.52 EE1033 pKa = 3.91 YY1034 pKa = 10.72 RR1035 pKa = 11.84 QYY1037 pKa = 8.49 TTTTGKK1043 pKa = 9.69 HH1044 pKa = 5.26 RR1045 pKa = 11.84 NNPVICKK1052 pKa = 7.17 PTPNLRR1058 pKa = 11.84 QHH1060 pKa = 6.15 YY1061 pKa = 10.11 NEE1063 pKa = 5.01 EE1064 pKa = 3.82 EE1065 pKa = 4.25 DD1066 pKa = 4.94 KK1067 pKa = 11.24 FDD1069 pKa = 3.58 DD1070 pKa = 4.53 TIYY1073 pKa = 10.88 GAGDD1077 pKa = 3.25 NMYY1080 pKa = 10.81 KK1081 pKa = 10.37 VLTLKK1086 pKa = 10.79 QIVEE1090 pKa = 4.41 NISAKK1095 pKa = 9.77 IKK1097 pKa = 10.62 KK1098 pKa = 9.49 FEE1100 pKa = 4.41 KK1101 pKa = 9.9 KK1102 pKa = 9.92 FKK1104 pKa = 10.05 NARR1107 pKa = 11.84 SFNLKK1112 pKa = 10.34 SKK1114 pKa = 10.42 IVALKK1119 pKa = 10.47 AKK1121 pKa = 8.29 KK1122 pKa = 8.99 TNITDD1127 pKa = 3.56 QQITEE1132 pKa = 4.07 HH1133 pKa = 6.73 FKK1135 pKa = 10.19 DD1136 pKa = 3.14 QGYY1139 pKa = 10.37 SRR1141 pKa = 11.84 IEE1143 pKa = 4.18 VMQHH1147 pKa = 4.27 LHH1149 pKa = 5.19 QGKK1152 pKa = 8.37 FQTQEE1157 pKa = 3.78 MINFLNSPRR1166 pKa = 11.84 FKK1168 pKa = 11.07 QEE1170 pKa = 2.78 IDD1172 pKa = 3.38 TIAIQDD1178 pKa = 3.47 QMQDD1182 pKa = 2.96 VTQNEE1187 pKa = 4.54 TLDD1190 pKa = 3.69 HH1191 pKa = 5.98 FVVNIKK1197 pKa = 10.86 GPGGTGKK1204 pKa = 7.49 TTIARR1209 pKa = 11.84 KK1210 pKa = 9.12 AATNLKK1216 pKa = 10.37 LMLGMPLVEE1225 pKa = 4.98 FNYY1228 pKa = 10.56 LDD1230 pKa = 3.76 RR1231 pKa = 11.84 EE1232 pKa = 4.37 SAKK1235 pKa = 10.87 SITKK1239 pKa = 9.72 PSIIILNDD1247 pKa = 3.34 CVYY1250 pKa = 11.29 DD1251 pKa = 3.48 EE1252 pKa = 5.02 LMYY1255 pKa = 10.82 INFYY1259 pKa = 11.26 DD1260 pKa = 4.5 SLPKK1264 pKa = 10.36 ACIIFVTHH1272 pKa = 6.44 NLVLNRR1278 pKa = 11.84 DD1279 pKa = 3.74 VVNVQNNLTNNNPVFEE1295 pKa = 4.42 YY1296 pKa = 11.04 LNTQDD1301 pKa = 5.49 DD1302 pKa = 4.98 SYY1304 pKa = 11.68 FPKK1307 pKa = 10.27 RR1308 pKa = 11.84 WFNNAIRR1315 pKa = 11.84 WYY1317 pKa = 8.37 GTQPRR1322 pKa = 11.84 APVWTVDD1329 pKa = 3.53 SQAKK1333 pKa = 7.67 MQINGFPRR1341 pKa = 11.84 RR1342 pKa = 11.84 LGLFGMHH1349 pKa = 5.91 MHH1351 pKa = 7.09 GGMISKK1357 pKa = 10.37 RR1358 pKa = 11.84 SISSCQMYY1366 pKa = 8.46 NTISGFRR1373 pKa = 11.84 VFKK1376 pKa = 10.61 IKK1378 pKa = 10.68 EE1379 pKa = 3.71 KK1380 pKa = 10.67 GDD1382 pKa = 3.5 RR1383 pKa = 11.84 KK1384 pKa = 9.74 GTLDD1388 pKa = 3.61 YY1389 pKa = 11.55 EE1390 pKa = 4.86 GVTEE1394 pKa = 4.94 SEE1396 pKa = 4.73 IISDD1400 pKa = 4.05 IYY1402 pKa = 11.56 SKK1404 pKa = 10.84 FNSYY1408 pKa = 9.87 CKK1410 pKa = 9.38 HH1411 pKa = 5.51 WKK1413 pKa = 9.44 IADD1416 pKa = 3.46 IKK1418 pKa = 10.66 KK1419 pKa = 10.56 LNSQLIDD1426 pKa = 3.46 EE1427 pKa = 6.16 LITQNSQDD1435 pKa = 3.49 IDD1437 pKa = 3.62 ILICAPSAEE1446 pKa = 4.37 DD1447 pKa = 5.26 LIKK1450 pKa = 10.23 FTNNPSALVKK1460 pKa = 9.5 TWAIPISTVSSGFTVKK1476 pKa = 7.98 TTSRR1480 pKa = 11.84 VNNCTFNFDD1489 pKa = 3.61 PTEE1492 pKa = 3.69 FAIPKK1497 pKa = 9.58 NSKK1500 pKa = 8.58 PDD1502 pKa = 2.99 QYY1504 pKa = 10.93 MAVARR1509 pKa = 11.84 NMYY1512 pKa = 9.8 RR1513 pKa = 11.84 IVMQGNVDD1521 pKa = 3.79 FTVIVKK1527 pKa = 10.7 AGDD1530 pKa = 3.56 FKK1532 pKa = 11.3 AICKK1536 pKa = 10.38 NGVINYY1542 pKa = 9.38 CSDD1545 pKa = 3.68 YY1546 pKa = 10.87 EE1547 pKa = 4.14 PEE1549 pKa = 4.04 EE1550 pKa = 3.93 TAFTHH1555 pKa = 6.46 TIVDD1559 pKa = 3.29 KK1560 pKa = 11.05 HH1561 pKa = 4.98 ITIQFTHH1568 pKa = 6.71 EE1569 pKa = 3.79 NTEE1572 pKa = 4.07 RR1573 pKa = 11.84 NLITNIHH1580 pKa = 6.42 LKK1582 pKa = 10.75 DD1583 pKa = 3.77 FAQIVHH1589 pKa = 6.33 NGIPPEE1595 pKa = 4.07 EE1596 pKa = 4.87 YY1597 pKa = 9.19 ITDD1600 pKa = 3.44 ITFDD1604 pKa = 3.56 HH1605 pKa = 6.84 YY1606 pKa = 11.95 LMFLNYY1612 pKa = 9.42 INNISTTEE1620 pKa = 3.99 SEE1622 pKa = 4.09 IVNYY1626 pKa = 9.26 MRR1628 pKa = 11.84 LLDD1631 pKa = 3.73 VKK1633 pKa = 10.83 QSVKK1637 pKa = 10.37 LAEE1640 pKa = 4.18 IQEE1643 pKa = 4.24 KK1644 pKa = 10.71 LGFVRR1649 pKa = 11.84 YY1650 pKa = 9.11 FKK1652 pKa = 10.89 YY1653 pKa = 10.81 FEE1655 pKa = 4.02 STSIYY1660 pKa = 10.18 KK1661 pKa = 10.56 FIMVLFGLATGVMFAFLINMLIKK1684 pKa = 9.81 MVWGSKK1690 pKa = 10.0 KK1691 pKa = 9.27 KK1692 pKa = 7.2 TTQLEE1697 pKa = 4.58 YY1698 pKa = 10.35 KK1699 pKa = 9.17 GHH1701 pKa = 6.77 KK1702 pKa = 9.01 IDD1704 pKa = 6.28 LVFDD1708 pKa = 3.81 WKK1710 pKa = 10.81 LNKK1713 pKa = 10.35 RR1714 pKa = 11.84 IDD1716 pKa = 3.76 DD1717 pKa = 3.84 RR1718 pKa = 11.84 ADD1720 pKa = 3.4 NLVCDD1725 pKa = 4.52 VACDD1729 pKa = 3.59 VLNYY1733 pKa = 10.3 KK1734 pKa = 10.45 DD1735 pKa = 4.77 DD1736 pKa = 5.08 LINFRR1741 pKa = 11.84 EE1742 pKa = 4.31 LKK1744 pKa = 10.59 NLIIQRR1750 pKa = 11.84 IKK1752 pKa = 10.95 FNLIDD1757 pKa = 3.59 NGFIKK1762 pKa = 10.59 SDD1764 pKa = 3.63 TCVEE1768 pKa = 4.19 LSNINIQSCKK1778 pKa = 6.06 EE1779 pKa = 4.2 TKK1781 pKa = 9.77 VLKK1784 pKa = 9.14 TKK1786 pKa = 10.29 PVEE1789 pKa = 4.1 TSNLTKK1795 pKa = 10.58 VEE1797 pKa = 4.11 GKK1799 pKa = 9.6 EE1800 pKa = 3.8 KK1801 pKa = 10.91 SSMYY1805 pKa = 10.72 DD1806 pKa = 3.13 KK1807 pKa = 10.52 QQKK1810 pKa = 9.41 NIKK1813 pKa = 9.85 LKK1815 pKa = 10.01 TKK1817 pKa = 10.28 EE1818 pKa = 3.77 ADD1820 pKa = 3.06 ALQAVLDD1827 pKa = 4.25 KK1828 pKa = 11.02 PSILSKK1834 pKa = 10.6 IEE1836 pKa = 3.82 NNLVKK1841 pKa = 10.8 VKK1843 pKa = 8.45 TTMGDD1848 pKa = 3.48 GLSKK1852 pKa = 10.55 SLYY1855 pKa = 10.73 GLDD1858 pKa = 3.34 IGNGVIITMYY1868 pKa = 10.94 HH1869 pKa = 5.7 NLCLVNTNSNKK1880 pKa = 9.9 YY1881 pKa = 9.78 EE1882 pKa = 4.17 EE1883 pKa = 4.84 ADD1885 pKa = 3.42 HH1886 pKa = 6.39 VQTTVKK1892 pKa = 10.79 YY1893 pKa = 10.24 LVTDD1897 pKa = 3.41 EE1898 pKa = 4.22 EE1899 pKa = 5.13 FEE1901 pKa = 4.54 VKK1903 pKa = 10.11 PVMKK1907 pKa = 10.32 DD1908 pKa = 3.18 PYY1910 pKa = 9.55 HH1911 pKa = 7.31 DD1912 pKa = 3.17 IVIFQIQNRR1921 pKa = 11.84 NGYY1924 pKa = 7.46 NARR1927 pKa = 11.84 ANLIKK1932 pKa = 10.9 YY1933 pKa = 7.56 FIRR1936 pKa = 11.84 DD1937 pKa = 3.41 KK1938 pKa = 11.34 NRR1940 pKa = 11.84 TKK1942 pKa = 9.98 HH1943 pKa = 5.43 TMSEE1947 pKa = 4.23 MYY1949 pKa = 10.1 TYY1951 pKa = 11.41 DD1952 pKa = 3.48 RR1953 pKa = 11.84 VKK1955 pKa = 11.27 NNNNGLNRR1963 pKa = 11.84 TKK1965 pKa = 10.89 LVGTTANIQLVKK1977 pKa = 10.4 DD1978 pKa = 3.87 TVNLTKK1984 pKa = 10.64 GAFVYY1989 pKa = 8.37 VTSVLFCYY1997 pKa = 10.32 GMATKK2002 pKa = 10.35 EE2003 pKa = 4.17 GDD2005 pKa = 3.64 CGLPLYY2011 pKa = 10.54 ALNDD2015 pKa = 3.46 SHH2017 pKa = 7.4 EE2018 pKa = 4.43 ILCGLHH2024 pKa = 5.8 YY2025 pKa = 10.64 GGNASHH2031 pKa = 7.12 IGAVQITQEE2040 pKa = 4.09 YY2041 pKa = 9.99 LEE2043 pKa = 4.44 TVYY2046 pKa = 10.94 SQIMEE2051 pKa = 4.18 IEE2053 pKa = 4.22 DD2054 pKa = 3.79 EE2055 pKa = 4.39 EE2056 pKa = 4.83 FFDD2059 pKa = 4.69 AVEE2062 pKa = 4.49 IEE2064 pKa = 4.03 LDD2066 pKa = 3.65 QNEE2069 pKa = 5.07 LEE2071 pKa = 4.54 DD2072 pKa = 3.42 EE2073 pKa = 4.73 TYY2075 pKa = 11.02 FEE2077 pKa = 4.29 FTEE2080 pKa = 4.38 VTFDD2084 pKa = 3.54 AFGKK2088 pKa = 10.48 EE2089 pKa = 3.93 EE2090 pKa = 4.21 TVVLDD2095 pKa = 3.5 NHH2097 pKa = 6.56 SLSILQDD2104 pKa = 3.31 CDD2106 pKa = 3.96 LGSKK2110 pKa = 7.58 QTFEE2114 pKa = 4.12 CLEE2117 pKa = 4.07 VGEE2120 pKa = 4.2 NTEE2123 pKa = 4.11 PFGYY2127 pKa = 5.99 THH2129 pKa = 6.98 KK2130 pKa = 10.56 GARR2133 pKa = 11.84 AFRR2136 pKa = 11.84 LKK2138 pKa = 10.37 SKK2140 pKa = 10.13 YY2141 pKa = 10.04 IPTPYY2146 pKa = 9.53 TDD2148 pKa = 5.04 EE2149 pKa = 4.3 IDD2151 pKa = 3.42 EE2152 pKa = 4.85 RR2153 pKa = 11.84 IPRR2156 pKa = 11.84 EE2157 pKa = 4.05 EE2158 pKa = 4.13 MNSATSNKK2166 pKa = 9.47 KK2167 pKa = 10.25 VEE2169 pKa = 4.69 DD2170 pKa = 4.04 PSNLPVNRR2178 pKa = 11.84 RR2179 pKa = 11.84 GEE2181 pKa = 3.87 PSILIGQQDD2190 pKa = 4.05 KK2191 pKa = 11.65 LNDD2194 pKa = 3.7 PVDD2197 pKa = 3.87 ALGKK2201 pKa = 10.32 SLGDD2205 pKa = 3.34 KK2206 pKa = 10.34 YY2207 pKa = 10.85 LARR2210 pKa = 11.84 ALEE2213 pKa = 3.93 ILIPHH2218 pKa = 5.79 YY2219 pKa = 10.37 KK2220 pKa = 9.89 KK2221 pKa = 10.55 LYY2223 pKa = 10.08 GRR2225 pKa = 11.84 FKK2227 pKa = 10.93 HH2228 pKa = 5.78 RR2229 pKa = 11.84 TLTDD2233 pKa = 3.48 LEE2235 pKa = 4.88 VINGTYY2241 pKa = 10.11 INPRR2245 pKa = 11.84 CPSFQNLEE2253 pKa = 4.45 PIDD2256 pKa = 3.67 RR2257 pKa = 11.84 TGSIGYY2263 pKa = 9.62 DD2264 pKa = 3.31 VTSVFHH2270 pKa = 6.43 IQHH2273 pKa = 6.38 KK2274 pKa = 10.8 NDD2276 pKa = 3.13 VLKK2279 pKa = 10.95 LFKK2282 pKa = 10.04 TLPCGRR2288 pKa = 11.84 HH2289 pKa = 5.29 IYY2291 pKa = 10.14 HH2292 pKa = 6.55 YY2293 pKa = 10.89 ADD2295 pKa = 3.49 TEE2297 pKa = 3.72 AARR2300 pKa = 11.84 YY2301 pKa = 8.83 VRR2303 pKa = 11.84 RR2304 pKa = 11.84 QEE2306 pKa = 4.18 EE2307 pKa = 4.49 VTLHH2311 pKa = 5.61 YY2312 pKa = 10.02 WEE2314 pKa = 3.81 QDD2316 pKa = 3.09 KK2317 pKa = 11.17 RR2318 pKa = 11.84 CEE2320 pKa = 4.38 SLVQSNLKK2328 pKa = 10.68 CEE2330 pKa = 4.06 LRR2332 pKa = 11.84 PLEE2335 pKa = 4.13 KK2336 pKa = 10.75 VRR2338 pKa = 11.84 VGKK2341 pKa = 7.62 TRR2343 pKa = 11.84 CFEE2346 pKa = 4.24 SFTMANSNATRR2357 pKa = 11.84 RR2358 pKa = 11.84 ILGTLFAAIKK2368 pKa = 8.95 MYY2370 pKa = 10.36 RR2371 pKa = 11.84 SEE2373 pKa = 4.47 GFAQVGIDD2381 pKa = 3.26 TVNFQQLYY2389 pKa = 10.51 EE2390 pKa = 4.08 RR2391 pKa = 11.84 FQRR2394 pKa = 11.84 LGQFGEE2400 pKa = 4.49 AGDD2403 pKa = 4.02 FSAWDD2408 pKa = 3.36 KK2409 pKa = 11.51 HH2410 pKa = 6.23 LMPNAIEE2417 pKa = 4.5 LVTDD2421 pKa = 3.94 LWTEE2425 pKa = 3.84 TFFASWEE2432 pKa = 4.34 EE2433 pKa = 3.58 VDD2435 pKa = 3.07 PTYY2438 pKa = 10.52 RR2439 pKa = 11.84 IKK2441 pKa = 10.46 IRR2443 pKa = 11.84 NQIHH2447 pKa = 5.99 QILVSNYY2454 pKa = 8.82 KK2455 pKa = 10.52 AIIIADD2461 pKa = 3.53 GNVFTKK2467 pKa = 10.56 QRR2469 pKa = 11.84 GNCSGAQTTTHH2480 pKa = 6.7 LNGSVNDD2487 pKa = 4.56 LYY2489 pKa = 10.96 RR2490 pKa = 11.84 VACILYY2496 pKa = 10.66 LIDD2499 pKa = 3.38 QHH2501 pKa = 6.4 NAHH2504 pKa = 6.77 CEE2506 pKa = 3.6 ISPKK2510 pKa = 10.42 SEE2512 pKa = 3.43 IKK2514 pKa = 10.07 EE2515 pKa = 4.04 KK2516 pKa = 11.08 YY2517 pKa = 7.88 EE2518 pKa = 3.58 QIPFIEE2524 pKa = 5.07 RR2525 pKa = 11.84 YY2526 pKa = 6.73 TRR2528 pKa = 11.84 QMQLDD2533 pKa = 3.66 KK2534 pKa = 11.84 VEE2536 pKa = 4.25 INSMEE2541 pKa = 5.67 DD2542 pKa = 2.78 ILKK2545 pKa = 8.59 ITDD2548 pKa = 3.06 WVDD2551 pKa = 3.17 YY2552 pKa = 10.94 GDD2554 pKa = 5.33 DD2555 pKa = 3.64 LASVINLNYY2564 pKa = 10.23 VNILNFVSFKK2574 pKa = 9.94 MAYY2577 pKa = 9.68 NYY2579 pKa = 10.75 LFGITYY2585 pKa = 9.27 DD2586 pKa = 3.75 SPAKK2590 pKa = 10.38 DD2591 pKa = 3.38 GSIALLTPLIKK2602 pKa = 10.65 LSFISRR2608 pKa = 11.84 TFHH2611 pKa = 7.74 LDD2613 pKa = 2.94 EE2614 pKa = 4.77 NLNIITPRR2622 pKa = 11.84 LKK2624 pKa = 10.51 LSSINRR2630 pKa = 11.84 LLHH2633 pKa = 4.96 WTTSIDD2639 pKa = 3.52 PDD2641 pKa = 3.6 QLKK2644 pKa = 9.85 TNLDD2648 pKa = 3.98 EE2649 pKa = 6.07 IFDD2652 pKa = 3.86 EE2653 pKa = 4.71 LKK2655 pKa = 10.75 FYY2657 pKa = 10.97 DD2658 pKa = 3.43 SSLYY2662 pKa = 10.35 SSYY2665 pKa = 10.83 IRR2667 pKa = 11.84 IVKK2670 pKa = 9.56 EE2671 pKa = 3.49 IINPYY2676 pKa = 9.22 LLKK2679 pKa = 10.53 NYY2681 pKa = 7.41 RR2682 pKa = 11.84 TAYY2685 pKa = 10.28 SPPNYY2690 pKa = 9.61 HH2691 pKa = 7.26 LLRR2694 pKa = 11.84 GHH2696 pKa = 6.21 YY2697 pKa = 9.54 EE2698 pKa = 3.91 NAVKK2702 pKa = 10.42 NVRR2705 pKa = 11.84 KK2706 pKa = 9.23 EE2707 pKa = 3.39 QDD2709 pKa = 2.96 AYY2711 pKa = 10.16 IDD2713 pKa = 3.27 ASLRR2717 pKa = 11.84 INEE2720 pKa = 4.19 KK2721 pKa = 10.94 NKK2723 pKa = 9.97 ILEE2726 pKa = 4.15 NFQRR2730 pKa = 11.84 IIDD2733 pKa = 4.19 LFATQGTQLTRR2744 pKa = 11.84 RR2745 pKa = 11.84 IPDD2748 pKa = 3.49 LEE2750 pKa = 4.39 TNLLSEE2756 pKa = 4.21 NMTPEE2761 pKa = 4.15 TIKK2764 pKa = 10.76 EE2765 pKa = 4.11 YY2766 pKa = 10.92 FEE2768 pKa = 4.75 SLFIRR2773 pKa = 11.84 MRR2775 pKa = 11.84 VNTQLKK2781 pKa = 10.31 ISGLPAKK2788 pKa = 9.4 VTAEE2792 pKa = 3.77 NGAVFWSISCEE2803 pKa = 3.91 PLYY2806 pKa = 10.27 DD2807 pKa = 3.74 TSLKK2811 pKa = 10.34 EE2812 pKa = 3.93 YY2813 pKa = 10.55 RR2814 pKa = 11.84 KK2815 pKa = 9.97 DD2816 pKa = 3.29 LQRR2819 pKa = 11.84 ILQSSRR2825 pKa = 11.84 HH2826 pKa = 4.18 FTFVTVEE2833 pKa = 4.03 DD2834 pKa = 4.08 LEE2836 pKa = 4.75 IYY2838 pKa = 10.13 IPNPLKK2844 pKa = 10.56 RR2845 pKa = 11.84 IQFRR2849 pKa = 11.84 VIQRR2853 pKa = 11.84 GEE2855 pKa = 4.14 SVGKK2859 pKa = 9.64 EE2860 pKa = 3.81 FSVHH2864 pKa = 5.31 EE2865 pKa = 4.16 LRR2867 pKa = 11.84 DD2868 pKa = 3.51 ALFNIQAATSAAMVDD2883 pKa = 3.9 PMPKK2887 pKa = 8.4 VTPGAPVPLQDD2898 pKa = 3.45 SGLPVGLHH2906 pKa = 5.34 QLGFSQKK2913 pKa = 7.95 STAMLAYY2920 pKa = 9.73 EE2921 pKa = 4.22 YY2922 pKa = 11.1 APLANYY2928 pKa = 7.7 TIPVGSTSGKK2938 pKa = 10.39 VILNLTRR2945 pKa = 11.84 TDD2947 pKa = 3.57 LVNEE2951 pKa = 4.28 FMRR2954 pKa = 11.84 ACKK2957 pKa = 10.02 TGDD2960 pKa = 2.93 SYY2962 pKa = 12.14 YY2963 pKa = 11.1 NGSFKK2968 pKa = 11.16 VKK2970 pKa = 10.15 FVSQTNPGLTGTLLIGMTRR2989 pKa = 11.84 SKK2991 pKa = 10.83 LDD2993 pKa = 3.42 SPTEE2997 pKa = 3.54 TDD2999 pKa = 3.31 MLIKK3003 pKa = 9.29 QTYY3006 pKa = 9.04 QIDD3009 pKa = 4.21 GNSSQNFEE3017 pKa = 4.23 LTISPFTDD3025 pKa = 3.1 DD3026 pKa = 3.12 VVKK3029 pKa = 10.87 ARR3031 pKa = 11.84 FAWPPSEE3038 pKa = 5.8 ADD3040 pKa = 3.4 DD3041 pKa = 5.0 DD3042 pKa = 4.84 YY3043 pKa = 11.89 YY3044 pKa = 10.45 PALVIIVKK3052 pKa = 10.22 CDD3054 pKa = 3.65 FVSTFDD3060 pKa = 3.73 NPSLYY3065 pKa = 10.73 SQIQLYY3071 pKa = 7.96 TAFSPDD3077 pKa = 2.89 FVTFFNGFPKK3087 pKa = 9.61 NTGYY3091 pKa = 8.17 NTRR3094 pKa = 11.84 DD3095 pKa = 3.31 AQLSINTVIPLDD3107 pKa = 3.98 DD3108 pKa = 3.75 VLGKK3112 pKa = 9.79 DD3113 pKa = 3.36 VRR3115 pKa = 11.84 LFTDD3119 pKa = 4.37 GNLFTPNIIQVTQSQVEE3136 pKa = 4.54 VVASDD3141 pKa = 3.68 TLHH3144 pKa = 5.56 TAEE3147 pKa = 4.7 AFEE3150 pKa = 5.02 IKK3152 pKa = 9.87 DD3153 pKa = 3.37 QKK3155 pKa = 10.88 RR3156 pKa = 11.84 ITRR3159 pKa = 11.84 TWATASGWGSFISYY3173 pKa = 9.89 EE3174 pKa = 3.94 NSLLQLRR3181 pKa = 11.84 NPKK3184 pKa = 10.13 SSTVINSIEE3193 pKa = 3.92 LLIDD3197 pKa = 3.54 YY3198 pKa = 10.97 AEE3200 pKa = 4.96 GPSFTLNSDD3209 pKa = 2.7 VDD3211 pKa = 3.79 INEE3214 pKa = 3.78 KK3215 pKa = 10.38 RR3216 pKa = 11.84 IEE3218 pKa = 3.89 LASIGKK3224 pKa = 9.47 VDD3226 pKa = 4.89 DD3227 pKa = 3.55 RR3228 pKa = 11.84 TNYY3231 pKa = 9.69 MDD3233 pKa = 4.97 IEE3235 pKa = 4.47 FTNVWCKK3242 pKa = 10.71 CYY3244 pKa = 10.62 VSQKK3248 pKa = 10.27 EE3249 pKa = 3.84 RR3250 pKa = 11.84 DD3251 pKa = 3.49 EE3252 pKa = 4.37 KK3253 pKa = 11.12 LDD3255 pKa = 3.7 RR3256 pKa = 11.84 KK3257 pKa = 10.56 NMQTFLKK3264 pKa = 10.22 YY3265 pKa = 9.99 IEE3267 pKa = 4.76 PNFVSDD3273 pKa = 3.38 VTTYY3277 pKa = 10.78 QVLAPLIKK3285 pKa = 10.76 VKK3287 pKa = 10.26 IDD3289 pKa = 3.57 NKK3291 pKa = 10.9 NKK3293 pKa = 9.61 LQSFSVTFDD3302 pKa = 3.06 FTEE3305 pKa = 4.0 LHH3307 pKa = 6.81 DD3308 pKa = 4.21 KK3309 pKa = 11.16 VGTLFTMLSLNADD3322 pKa = 3.42 DD3323 pKa = 5.06 TSFNCLLTSVYY3334 pKa = 10.51 GFNFTLVIPFDD3345 pKa = 4.21 FSKK3348 pKa = 9.84 LTQANLANFPDD3359 pKa = 5.84 AITLPAGASSLQAVKK3374 pKa = 10.67 LPFVVPPASTGAVNAAGSTLLPNISIFDD3402 pKa = 3.86 NLSKK3406 pKa = 11.01 VLATDD3411 pKa = 5.22 KK3412 pKa = 10.57 IYY3414 pKa = 10.75 QLQLTTKK3421 pKa = 10.05 DD3422 pKa = 3.53 YY3423 pKa = 11.3 SDD3425 pKa = 3.92 LVGTFIFHH3433 pKa = 6.39 GPKK3436 pKa = 8.9 RR3437 pKa = 11.84 TCFFNTNKK3445 pKa = 9.69 IEE3447 pKa = 4.07 YY3448 pKa = 9.21 LVSSYY3453 pKa = 10.15 MSQEE3457 pKa = 3.45 LNLRR3461 pKa = 11.84 VNNVISLNAQLPVTKK3476 pKa = 9.76 YY3477 pKa = 9.57 NSSAFVQRR3485 pKa = 11.84 NTKK3488 pKa = 10.06 SLVRR3492 pKa = 11.84 RR3493 pKa = 11.84 EE3494 pKa = 3.85 ISAEE3498 pKa = 3.93 TFNVQGAAASVGAGALMGVGQGLGNYY3524 pKa = 10.49 LNMQQNFQNNKK3535 pKa = 9.44 EE3536 pKa = 4.09 LLLLNQGFNKK3546 pKa = 9.76 EE3547 pKa = 3.98 QAKK3550 pKa = 9.83 MMLEE3554 pKa = 3.93 MQGANQLAAISAYY3567 pKa = 10.51 GEE3569 pKa = 4.15 NQLGALGIKK3578 pKa = 9.45 GANTLNAIAAQGEE3591 pKa = 4.4 NTKK3594 pKa = 10.55 EE3595 pKa = 3.83 QMFLQHH3601 pKa = 6.35 TLNNLNTPGMSVQRR3615 pKa = 11.84 SQNQNFVSGGHH3626 pKa = 5.73 QYY3628 pKa = 11.29 PDD3630 pKa = 3.67 TQNSTTLEE3638 pKa = 4.18 TPIEE3642 pKa = 4.13 QFDD3645 pKa = 3.98 LHH3647 pKa = 6.02 TGARR3651 pKa = 11.84 IKK3653 pKa = 9.24 QTSPIQPTVNSAGDD3667 pKa = 3.73 DD3668 pKa = 3.84 APNTSVDD3675 pKa = 3.71 SLSRR3679 pKa = 11.84 AAIEE3683 pKa = 3.8 NTLFEE3688 pKa = 4.58 EE3689 pKa = 5.56 SYY3691 pKa = 11.03 HH3692 pKa = 7.05 SPTPNKK3698 pKa = 10.39 NPLAGAAGEE3707 pKa = 4.33 VRR3709 pKa = 11.84 DD3710 pKa = 4.0 GMEE3713 pKa = 4.3 NLVDD3717 pKa = 4.1 TIGDD3721 pKa = 3.66 YY3722 pKa = 9.02 RR3723 pKa = 11.84 TLEE3726 pKa = 4.27 NLNMHH3731 pKa = 6.67 DD3732 pKa = 3.81 TSSTPTQQTRR3742 pKa = 11.84 AMPKK3746 pKa = 9.02 NKK3748 pKa = 9.62 LANSHH3753 pKa = 6.22 GLGADD3758 pKa = 3.39 PGTKK3762 pKa = 9.83 LSQMKK3767 pKa = 9.93 FPGVTTSVSVII3778 pKa = 3.53
Molecular weight: 432.37 kDa
Isoelectric point according different methods:
IPC2.protein.svr19 5.979
IPC2_protein 5.995
IPC_protein 6.059
Toseland 6.389
ProMoST 6.427
Dawson 6.338
Bjellqvist 6.364
Wikipedia 6.351
Rodwell 6.338
Grimsley 6.532
Solomon 6.338
Lehninger 6.338
Nozaki 6.62
DTASelect 6.795
Thurlkill 6.81
EMBOSS 6.781
Sillero 6.722
Patrickios 4.202
IPC_peptide 6.364
IPC2_peptide 6.59
IPC2.peptide.svr19 6.673
Peptides (in silico digests for buttom-up proteomics)
Below you can find
in silico digests of the whole proteome with Trypsin, Chymotrypsin, Trypsin+LysC, LysN, ArgC proteases suitable for different mass spec machines.
Try ESI
ChTry ESI
ArgC ESI
LysN ESI
TryLysC ESI
Try MALDI
ChTry MALDI
ArgC MALDI
LysN MALDI
TryLysC MALDI
Try LTQ
ChTry LTQ
ArgC LTQ
LysN LTQ
TryLysC LTQ
Try MSlow
ChTry MSlow
ArgC MSlow
LysN MSlow
TryLysC MSlow
Try MShigh
ChTry MShigh
ArgC MShigh
LysN MShigh
TryLysC MShigh
General Statistics
Number of major isoforms
Number of additional isoforms
Number of all proteins
Number of amino acids
Min. Seq. Length
Max. Seq. Length
Avg. Seq. Length
Avg. Mol. Weight
1
0
1
3778
3778
3778
3778.0
432.37
Amino acid frequency
Ala
Cys
Asp
Glu
Phe
Gly
His
Ile
Lys
Leu
5.109 ± 0.0
1.244 ± 0.0
5.85 ± 0.0
6.22 ± 0.0
5.188 ± 0.0
4.367 ± 0.0
2.012 ± 0.0
7.676 ± 0.0
7.253 ± 0.0
8.841 ± 0.0
Met
Asn
Gln
Pro
Arg
Ser
Thr
Val
Trp
Tyr
2.356 ± 0.0
7.014 ± 0.0
3.547 ± 0.0
4.791 ± 0.0
4.129 ± 0.0
6.406 ± 0.0
7.094 ± 0.0
6.141 ± 0.0
0.662 ± 0.0
4.103 ± 0.0
Note: For amino acid frequency statistics the error has been estimated with the bootstraping (x100) at the protein level
Most of the basic statistics you can see at this page can be downloaded from this CSV file
For dipeptide frequency statistics click here