Amino acid dipepetide frequency for Cocleimonas flava

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	7.156AlaAla: 7.156 ± 0.114	0.862AlaCys: 0.862 ± 0.03	4.558AlaAsp: 4.558 ± 0.074	5.461AlaGlu: 5.461 ± 0.092	3.213AlaPhe: 3.213 ± 0.05	5.867AlaGly: 5.867 ± 0.088	1.466AlaHis: 1.466 ± 0.038	5.931AlaIle: 5.931 ± 0.078	5.086AlaLys: 5.086 ± 0.074	8.419AlaLeu: 8.419 ± 0.108	2.39AlaMet: 2.39 ± 0.048	3.468AlaAsn: 3.468 ± 0.054	2.752AlaPro: 2.752 ± 0.056	2.667AlaGln: 2.667 ± 0.049	3.156AlaArg: 3.156 ± 0.054	5.257AlaSer: 5.257 ± 0.074	4.468AlaThr: 4.468 ± 0.076	5.499AlaVal: 5.499 ± 0.074	0.931AlaTrp: 0.931 ± 0.027	2.3AlaTyr: 2.3 ± 0.042	0.0AlaXaa: 0.0 ± 0.0
Cys	0.644CysAla: 0.644 ± 0.023	0.115CysCys: 0.115 ± 0.011	0.544CysAsp: 0.544 ± 0.019	0.546CysGlu: 0.546 ± 0.024	0.378CysPhe: 0.378 ± 0.016	0.855CysGly: 0.855 ± 0.029	0.288CysHis: 0.288 ± 0.017	0.546CysIle: 0.546 ± 0.021	0.459CysLys: 0.459 ± 0.022	0.818CysLeu: 0.818 ± 0.027	0.189CysMet: 0.189 ± 0.01	0.39CysAsn: 0.39 ± 0.02	0.435CysPro: 0.435 ± 0.021	0.295CysGln: 0.295 ± 0.017	0.37CysArg: 0.37 ± 0.018	0.649CysSer: 0.649 ± 0.025	0.486CysThr: 0.486 ± 0.023	0.561CysVal: 0.561 ± 0.022	0.098CysTrp: 0.098 ± 0.008	0.276CysTyr: 0.276 ± 0.016	0.0CysXaa: 0.0 ± 0.0
Asp	4.53AspAla: 4.53 ± 0.071	0.524AspCys: 0.524 ± 0.02	3.675AspAsp: 3.675 ± 0.063	4.127AspGlu: 4.127 ± 0.061	2.568AspPhe: 2.568 ± 0.043	3.847AspGly: 3.847 ± 0.074	1.128AspHis: 1.128 ± 0.029	4.395AspIle: 4.395 ± 0.061	3.776AspLys: 3.776 ± 0.062	5.468AspLeu: 5.468 ± 0.073	1.427AspMet: 1.427 ± 0.034	2.764AspAsn: 2.764 ± 0.047	2.247AspPro: 2.247 ± 0.055	2.05AspGln: 2.05 ± 0.043	2.285AspArg: 2.285 ± 0.048	3.715AspSer: 3.715 ± 0.064	3.157AspThr: 3.157 ± 0.067	3.977AspVal: 3.977 ± 0.063	0.836AspTrp: 0.836 ± 0.026	2.097AspTyr: 2.097 ± 0.044	0.0AspXaa: 0.0 ± 0.0
Glu	5.128GluAla: 5.128 ± 0.088	0.456GluCys: 0.456 ± 0.018	3.548GluAsp: 3.548 ± 0.061	4.308GluGlu: 4.308 ± 0.081	2.394GluPhe: 2.394 ± 0.048	3.762GluGly: 3.762 ± 0.06	1.379GluHis: 1.379 ± 0.038	4.696GluIle: 4.696 ± 0.064	4.743GluLys: 4.743 ± 0.079	6.366GluLeu: 6.366 ± 0.084	1.684GluMet: 1.684 ± 0.037	3.468GluAsn: 3.468 ± 0.058	1.944GluPro: 1.944 ± 0.046	2.677GluGln: 2.677 ± 0.047	2.747GluArg: 2.747 ± 0.058	4.037GluSer: 4.037 ± 0.06	3.721GluThr: 3.721 ± 0.062	4.086GluVal: 4.086 ± 0.063	0.725GluTrp: 0.725 ± 0.022	1.977GluTyr: 1.977 ± 0.04	0.0GluXaa: 0.0 ± 0.0
Phe	3.339PheAla: 3.339 ± 0.063	0.425PheCys: 0.425 ± 0.018	2.557PheAsp: 2.557 ± 0.043	2.324PheGlu: 2.324 ± 0.044	1.913PhePhe: 1.913 ± 0.044	3.04PheGly: 3.04 ± 0.057	0.796PheHis: 0.796 ± 0.023	3.081PheIle: 3.081 ± 0.054	2.332PheLys: 2.332 ± 0.049	3.847PheLeu: 3.847 ± 0.066	1.112PheMet: 1.112 ± 0.029	1.997PheAsn: 1.997 ± 0.04	1.597PhePro: 1.597 ± 0.035	1.179PheGln: 1.179 ± 0.027	1.446PheArg: 1.446 ± 0.032	3.378PheSer: 3.378 ± 0.055	2.369PheThr: 2.369 ± 0.049	2.666PheVal: 2.666 ± 0.045	0.538PheTrp: 0.538 ± 0.02	1.377PheTyr: 1.377 ± 0.032	0.0PheXaa: 0.0 ± 0.0
Gly	5.143GlyAla: 5.143 ± 0.085	0.765GlyCys: 0.765 ± 0.028	3.794GlyAsp: 3.794 ± 0.057	4.182GlyGlu: 4.182 ± 0.061	3.206GlyPhe: 3.206 ± 0.051	5.073GlyGly: 5.073 ± 0.09	1.425GlyHis: 1.425 ± 0.032	5.137GlyIle: 5.137 ± 0.067	4.476GlyLys: 4.476 ± 0.068	6.806GlyLeu: 6.806 ± 0.08	2.025GlyMet: 2.025 ± 0.041	2.95GlyAsn: 2.95 ± 0.052	1.714GlyPro: 1.714 ± 0.042	2.216GlyGln: 2.216 ± 0.04	2.769GlyArg: 2.769 ± 0.053	4.478GlySer: 4.478 ± 0.064	3.761GlyThr: 3.761 ± 0.074	5.035GlyVal: 5.035 ± 0.082	0.963GlyTrp: 0.963 ± 0.029	2.324GlyTyr: 2.324 ± 0.046	0.0GlyXaa: 0.0 ± 0.0
His	1.571HisAla: 1.571 ± 0.037	0.243HisCys: 0.243 ± 0.012	1.145HisAsp: 1.145 ± 0.035	1.201HisGlu: 1.201 ± 0.031	1.015HisPhe: 1.015 ± 0.03	1.414HisGly: 1.414 ± 0.031	0.582HisHis: 0.582 ± 0.023	1.397HisIle: 1.397 ± 0.033	1.14HisLys: 1.14 ± 0.031	2.07HisLeu: 2.07 ± 0.043	0.489HisMet: 0.489 ± 0.02	0.919HisAsn: 0.919 ± 0.029	1.154HisPro: 1.154 ± 0.034	0.883HisGln: 0.883 ± 0.03	0.914HisArg: 0.914 ± 0.028	1.332HisSer: 1.332 ± 0.036	1.063HisThr: 1.063 ± 0.031	1.149HisVal: 1.149 ± 0.028	0.312HisTrp: 0.312 ± 0.016	0.755HisTyr: 0.755 ± 0.023	0.0HisXaa: 0.0 ± 0.0
Ile	6.366IleAla: 6.366 ± 0.075	0.631IleCys: 0.631 ± 0.024	4.519IleAsp: 4.519 ± 0.058	4.81IleGlu: 4.81 ± 0.066	2.632IlePhe: 2.632 ± 0.055	4.919IleGly: 4.919 ± 0.072	1.354IleHis: 1.354 ± 0.027	4.738IleIle: 4.738 ± 0.081	4.39IleLys: 4.39 ± 0.066	6.097IleLeu: 6.097 ± 0.08	1.542IleMet: 1.542 ± 0.035	3.53IleAsn: 3.53 ± 0.065	3.192IlePro: 3.192 ± 0.051	2.357IleGln: 2.357 ± 0.048	2.785IleArg: 2.785 ± 0.048	5.311IleSer: 5.311 ± 0.065	4.176IleThr: 4.176 ± 0.082	4.458IleVal: 4.458 ± 0.062	0.673IleTrp: 0.673 ± 0.023	1.926IleTyr: 1.926 ± 0.037	0.0IleXaa: 0.0 ± 0.0
Lys	5.018LysAla: 5.018 ± 0.086	0.35LysCys: 0.35 ± 0.017	3.653LysAsp: 3.653 ± 0.062	4.093LysGlu: 4.093 ± 0.064	1.831LysPhe: 1.831 ± 0.042	3.858LysGly: 3.858 ± 0.057	1.421LysHis: 1.421 ± 0.037	4.007LysIle: 4.007 ± 0.063	4.647LysLys: 4.647 ± 0.086	5.881LysLeu: 5.881 ± 0.087	1.643LysMet: 1.643 ± 0.037	3.182LysAsn: 3.182 ± 0.058	2.861LysPro: 2.861 ± 0.06	2.998LysGln: 2.998 ± 0.055	3.025LysArg: 3.025 ± 0.056	4.146LysSer: 4.146 ± 0.064	3.871LysThr: 3.871 ± 0.058	4.071LysVal: 4.071 ± 0.065	0.642LysTrp: 0.642 ± 0.021	1.732LysTyr: 1.732 ± 0.043	0.0LysXaa: 0.0 ± 0.0
Leu	8.186LeuAla: 8.186 ± 0.079	0.817LeuCys: 0.817 ± 0.024	5.693LeuAsp: 5.693 ± 0.07	6.223LeuGlu: 6.223 ± 0.085	4.366LeuPhe: 4.366 ± 0.077	6.802LeuGly: 6.802 ± 0.078	1.875LeuHis: 1.875 ± 0.042	6.973LeuIle: 6.973 ± 0.089	6.163LeuLys: 6.163 ± 0.08	10.085LeuLeu: 10.085 ± 0.14	2.559LeuMet: 2.559 ± 0.042	4.614LeuAsn: 4.614 ± 0.063	4.34LeuPro: 4.34 ± 0.062	3.375LeuGln: 3.375 ± 0.059	3.97LeuArg: 3.97 ± 0.063	7.663LeuSer: 7.663 ± 0.096	5.463LeuThr: 5.463 ± 0.071	6.154LeuVal: 6.154 ± 0.074	1.021LeuTrp: 1.021 ± 0.029	2.543LeuTyr: 2.543 ± 0.048	0.0LeuXaa: 0.0 ± 0.0
Met	2.175MetAla: 2.175 ± 0.04	0.217MetCys: 0.217 ± 0.014	1.329MetAsp: 1.329 ± 0.035	1.353MetGlu: 1.353 ± 0.032	0.9MetPhe: 0.9 ± 0.029	1.858MetGly: 1.858 ± 0.051	0.517MetHis: 0.517 ± 0.022	1.7MetIle: 1.7 ± 0.034	1.799MetLys: 1.799 ± 0.044	2.591MetLeu: 2.591 ± 0.048	0.776MetMet: 0.776 ± 0.023	1.272MetAsn: 1.272 ± 0.03	1.275MetPro: 1.275 ± 0.032	1.079MetGln: 1.079 ± 0.03	1.179MetArg: 1.179 ± 0.028	2.055MetSer: 2.055 ± 0.041	1.569MetThr: 1.569 ± 0.034	1.639MetVal: 1.639 ± 0.034	0.213MetTrp: 0.213 ± 0.013	0.486MetTyr: 0.486 ± 0.018	0.0MetXaa: 0.0 ± 0.0
Asn	3.523AsnAla: 3.523 ± 0.054	0.445AsnCys: 0.445 ± 0.02	2.816AsnAsp: 2.816 ± 0.066	2.733AsnGlu: 2.733 ± 0.045	1.711AsnPhe: 1.711 ± 0.039	3.102AsnGly: 3.102 ± 0.068	1.032AsnHis: 1.032 ± 0.028	3.435AsnIle: 3.435 ± 0.06	3.294AsnLys: 3.294 ± 0.066	4.121AsnLeu: 4.121 ± 0.057	1.096AsnMet: 1.096 ± 0.032	2.722AsnAsn: 2.722 ± 0.058	2.441AsnPro: 2.441 ± 0.053	1.889AsnGln: 1.889 ± 0.042	1.885AsnArg: 1.885 ± 0.046	3.141AsnSer: 3.141 ± 0.051	3.005AsnThr: 3.005 ± 0.067	2.742AsnVal: 2.742 ± 0.051	0.616AsnTrp: 0.616 ± 0.025	1.529AsnTyr: 1.529 ± 0.038	0.0AsnXaa: 0.0 ± 0.0
Pro	3.237ProAla: 3.237 ± 0.063	0.275ProCys: 0.275 ± 0.015	2.698ProAsp: 2.698 ± 0.049	3.493ProGlu: 3.493 ± 0.055	1.732ProPhe: 1.732 ± 0.036	2.49ProGly: 2.49 ± 0.049	0.782ProHis: 0.782 ± 0.028	2.609ProIle: 2.609 ± 0.046	2.272ProLys: 2.272 ± 0.049	3.887ProLeu: 3.887 ± 0.052	0.944ProMet: 0.944 ± 0.03	1.778ProAsn: 1.778 ± 0.048	1.366ProPro: 1.366 ± 0.039	1.41ProGln: 1.41 ± 0.039	1.35ProArg: 1.35 ± 0.035	2.445ProSer: 2.445 ± 0.053	2.084ProThr: 2.084 ± 0.04	3.196ProVal: 3.196 ± 0.058	0.498ProTrp: 0.498 ± 0.021	1.231ProTyr: 1.231 ± 0.033	0.0ProXaa: 0.0 ± 0.0
Gln	3.155GlnAla: 3.155 ± 0.061	0.287GlnCys: 0.287 ± 0.014	1.776GlnAsp: 1.776 ± 0.039	2.142GlnGlu: 2.142 ± 0.05	1.353GlnPhe: 1.353 ± 0.034	2.343GlnGly: 2.343 ± 0.045	0.907GlnHis: 0.907 ± 0.025	2.545GlnIle: 2.545 ± 0.044	2.398GlnLys: 2.398 ± 0.049	3.942GlnLeu: 3.942 ± 0.064	0.925GlnMet: 0.925 ± 0.024	1.768GlnAsn: 1.768 ± 0.039	1.276GlnPro: 1.276 ± 0.032	2.224GlnGln: 2.224 ± 0.052	1.846GlnArg: 1.846 ± 0.043	2.546GlnSer: 2.546 ± 0.051	2.005GlnThr: 2.005 ± 0.039	2.155GlnVal: 2.155 ± 0.038	0.482GlnTrp: 0.482 ± 0.019	1.117GlnTyr: 1.117 ± 0.03	0.0GlnXaa: 0.0 ± 0.0
Arg	2.949ArgAla: 2.949 ± 0.05	0.383ArgCys: 0.383 ± 0.019	2.248ArgAsp: 2.248 ± 0.045	2.811ArgGlu: 2.811 ± 0.051	1.965ArgPhe: 1.965 ± 0.038	2.422ArgGly: 2.422 ± 0.046	0.95ArgHis: 0.95 ± 0.03	3.025ArgIle: 3.025 ± 0.054	2.597ArgLys: 2.597 ± 0.051	4.319ArgLeu: 4.319 ± 0.074	1.216ArgMet: 1.216 ± 0.03	1.892ArgAsn: 1.892 ± 0.042	1.5ArgPro: 1.5 ± 0.036	1.616ArgGln: 1.616 ± 0.043	1.955ArgArg: 1.955 ± 0.048	2.486ArgSer: 2.486 ± 0.044	1.993ArgThr: 1.993 ± 0.034	2.882ArgVal: 2.882 ± 0.05	0.543ArgTrp: 0.543 ± 0.019	1.526ArgTyr: 1.526 ± 0.037	0.0ArgXaa: 0.0 ± 0.0
Ser	5.414SerAla: 5.414 ± 0.075	0.633SerCys: 0.633 ± 0.026	4.122SerAsp: 4.122 ± 0.063	3.936SerGlu: 3.936 ± 0.053	3.009SerPhe: 3.009 ± 0.047	5.183SerGly: 5.183 ± 0.071	1.449SerHis: 1.449 ± 0.037	4.839SerIle: 4.839 ± 0.071	4.044SerLys: 4.044 ± 0.065	7.098SerLeu: 7.098 ± 0.099	1.824SerMet: 1.824 ± 0.037	3.448SerAsn: 3.448 ± 0.066	2.609SerPro: 2.609 ± 0.051	2.452SerGln: 2.452 ± 0.05	2.903SerArg: 2.903 ± 0.056	5.105SerSer: 5.105 ± 0.08	3.871SerThr: 3.871 ± 0.069	4.363SerVal: 4.363 ± 0.064	0.869SerTrp: 0.869 ± 0.03	2.057SerTyr: 2.057 ± 0.047	0.0SerXaa: 0.0 ± 0.0
Thr	4.707ThrAla: 4.707 ± 0.082	0.429ThrCys: 0.429 ± 0.019	3.381ThrAsp: 3.381 ± 0.067	3.435ThrGlu: 3.435 ± 0.06	2.268ThrPhe: 2.268 ± 0.05	4.235ThrGly: 4.235 ± 0.075	1.259ThrHis: 1.259 ± 0.03	3.856ThrIle: 3.856 ± 0.071	3.015ThrLys: 3.015 ± 0.048	6.091ThrLeu: 6.091 ± 0.082	1.261ThrMet: 1.261 ± 0.035	2.445ThrAsn: 2.445 ± 0.065	2.796ThrPro: 2.796 ± 0.052	2.14ThrGln: 2.14 ± 0.043	2.156ThrArg: 2.156 ± 0.04	3.742ThrSer: 3.742 ± 0.071	3.312ThrThr: 3.312 ± 0.08	4.025ThrVal: 4.025 ± 0.084	0.551ThrTrp: 0.551 ± 0.021	1.598ThrTyr: 1.598 ± 0.046	0.0ThrXaa: 0.0 ± 0.0
Val	5.593ValAla: 5.593 ± 0.075	0.643ValCys: 0.643 ± 0.022	4.082ValAsp: 4.082 ± 0.069	4.233ValGlu: 4.233 ± 0.062	2.87ValPhe: 2.87 ± 0.047	4.335ValGly: 4.335 ± 0.065	1.132ValHis: 1.132 ± 0.035	4.999ValIle: 4.999 ± 0.059	3.807ValLys: 3.807 ± 0.063	6.426ValLeu: 6.426 ± 0.076	1.885ValMet: 1.885 ± 0.042	2.908ValAsn: 2.908 ± 0.057	2.472ValPro: 2.472 ± 0.049	1.759ValGln: 1.759 ± 0.04	2.523ValArg: 2.523 ± 0.051	4.875ValSer: 4.875 ± 0.07	4.096ValThr: 4.096 ± 0.081	4.708ValVal: 4.708 ± 0.088	0.691ValTrp: 0.691 ± 0.026	1.828ValTyr: 1.828 ± 0.039	0.0ValXaa: 0.0 ± 0.0
Trp	0.758TrpAla: 0.758 ± 0.027	0.126TrpCys: 0.126 ± 0.01	0.693TrpAsp: 0.693 ± 0.023	0.611TrpGlu: 0.611 ± 0.025	0.594TrpPhe: 0.594 ± 0.025	0.814TrpGly: 0.814 ± 0.028	0.303TrpHis: 0.303 ± 0.015	0.711TrpIle: 0.711 ± 0.026	0.72TrpLys: 0.72 ± 0.024	1.434TrpLeu: 1.434 ± 0.034	0.363TrpMet: 0.363 ± 0.016	0.555TrpAsn: 0.555 ± 0.024	0.456TrpPro: 0.456 ± 0.018	0.558TrpGln: 0.558 ± 0.023	0.57TrpArg: 0.57 ± 0.02	0.726TrpSer: 0.726 ± 0.024	0.51TrpThr: 0.51 ± 0.019	0.799TrpVal: 0.799 ± 0.028	0.176TrpTrp: 0.176 ± 0.012	0.333TrpTyr: 0.333 ± 0.019	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.315TyrAla: 2.315 ± 0.043	0.315TyrCys: 0.315 ± 0.015	1.763TyrAsp: 1.763 ± 0.038	1.822TyrGlu: 1.822 ± 0.041	1.394TyrPhe: 1.394 ± 0.037	2.022TyrGly: 2.022 ± 0.039	0.702TyrHis: 0.702 ± 0.026	1.786TyrIle: 1.786 ± 0.042	1.771TyrLys: 1.771 ± 0.046	3.121TyrLeu: 3.121 ± 0.059	0.631TyrMet: 0.631 ± 0.025	1.212TyrAsn: 1.212 ± 0.034	1.35TyrPro: 1.35 ± 0.033	1.369TyrGln: 1.369 ± 0.035	1.441TyrArg: 1.441 ± 0.036	2.145TyrSer: 2.145 ± 0.046	1.723TyrThr: 1.723 ± 0.042	1.698TyrVal: 1.698 ± 0.035	0.432TyrTrp: 0.432 ± 0.02	1.057TyrTyr: 1.057 ± 0.032	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 3987 proteins (1293055 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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