Amino acid dipepetide frequency for Blackcurrant-associated closterovirus 1

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
6.144AlaAla: 6.144 ± 1.297
1.117AlaCys: 1.117 ± 0.456
3.165AlaAsp: 3.165 ± 0.814
3.724AlaGlu: 3.724 ± 0.671
4.655AlaPhe: 4.655 ± 0.93
3.724AlaGly: 3.724 ± 0.67
1.117AlaHis: 1.117 ± 0.485
3.165AlaIle: 3.165 ± 0.642
4.282AlaLys: 4.282 ± 0.82
4.655AlaLeu: 4.655 ± 0.809
0.559AlaMet: 0.559 ± 0.39
2.42AlaAsn: 2.42 ± 0.42
3.724AlaPro: 3.724 ± 1.258
0.745AlaGln: 0.745 ± 0.328
3.165AlaArg: 3.165 ± 1.145
4.841AlaSer: 4.841 ± 1.095
2.793AlaThr: 2.793 ± 1.155
5.586AlaVal: 5.586 ± 0.922
0.559AlaTrp: 0.559 ± 0.39
1.489AlaTyr: 1.489 ± 0.627
0.0AlaXaa: 0.0 ± 0.0
Cys
1.489CysAla: 1.489 ± 0.657
0.931CysCys: 0.931 ± 0.331
1.676CysAsp: 1.676 ± 0.719
1.489CysGlu: 1.489 ± 0.736
1.489CysPhe: 1.489 ± 0.595
1.862CysGly: 1.862 ± 0.67
0.186CysHis: 0.186 ± 0.103
0.931CysIle: 0.931 ± 0.331
1.117CysLys: 1.117 ± 0.237
3.165CysLeu: 3.165 ± 0.952
0.559CysMet: 0.559 ± 0.308
0.931CysAsn: 0.931 ± 0.367
0.559CysPro: 0.559 ± 0.308
0.931CysGln: 0.931 ± 0.355
1.676CysArg: 1.676 ± 0.333
2.607CysSer: 2.607 ± 0.736
1.489CysThr: 1.489 ± 0.811
1.489CysVal: 1.489 ± 0.684
0.0CysTrp: 0.0 ± 0.0
1.303CysTyr: 1.303 ± 0.43
0.0CysXaa: 0.0 ± 0.0
Asp
5.586AspAla: 5.586 ± 1.182
1.489AspCys: 1.489 ± 0.642
3.724AspAsp: 3.724 ± 0.563
2.607AspGlu: 2.607 ± 0.64
4.841AspPhe: 4.841 ± 0.629
2.607AspGly: 2.607 ± 0.37
0.745AspHis: 0.745 ± 0.344
3.165AspIle: 3.165 ± 0.684
3.351AspLys: 3.351 ± 1.304
6.144AspLeu: 6.144 ± 1.08
1.489AspMet: 1.489 ± 0.499
2.048AspAsn: 2.048 ± 0.74
2.234AspPro: 2.234 ± 0.376
1.117AspGln: 1.117 ± 0.455
2.42AspArg: 2.42 ± 0.532
6.144AspSer: 6.144 ± 1.484
1.862AspThr: 1.862 ± 0.485
5.586AspVal: 5.586 ± 1.643
0.0AspTrp: 0.0 ± 0.0
2.048AspTyr: 2.048 ± 0.44
0.0AspXaa: 0.0 ± 0.0
Glu
3.724GluAla: 3.724 ± 0.89
2.607GluCys: 2.607 ± 0.333
3.538GluAsp: 3.538 ± 0.891
2.793GluGlu: 2.793 ± 0.797
2.793GluPhe: 2.793 ± 0.422
2.234GluGly: 2.234 ± 0.503
0.745GluHis: 0.745 ± 0.328
3.538GluIle: 3.538 ± 1.047
4.096GluLys: 4.096 ± 0.938
5.399GluLeu: 5.399 ± 1.52
2.234GluMet: 2.234 ± 0.794
1.676GluAsn: 1.676 ± 0.582
1.117GluPro: 1.117 ± 0.326
1.303GluGln: 1.303 ± 0.613
3.351GluArg: 3.351 ± 1.023
5.213GluSer: 5.213 ± 1.055
2.979GluThr: 2.979 ± 0.798
5.027GluVal: 5.027 ± 0.894
0.372GluTrp: 0.372 ± 0.205
2.979GluTyr: 2.979 ± 1.409
0.0GluXaa: 0.0 ± 0.0
Phe
2.234PheAla: 2.234 ± 0.713
0.931PheCys: 0.931 ± 0.47
4.841PheAsp: 4.841 ± 0.764
3.724PheGlu: 3.724 ± 0.745
2.607PhePhe: 2.607 ± 2.21
3.538PheGly: 3.538 ± 0.887
1.489PheHis: 1.489 ± 0.82
2.234PheIle: 2.234 ± 0.332
4.282PheLys: 4.282 ± 1.23
5.772PheLeu: 5.772 ± 1.307
1.117PheMet: 1.117 ± 0.339
2.42PheAsn: 2.42 ± 0.813
1.862PhePro: 1.862 ± 0.636
0.745PheGln: 0.745 ± 0.265
3.91PheArg: 3.91 ± 0.968
5.772PheSer: 5.772 ± 1.366
2.979PheThr: 2.979 ± 0.645
2.607PheVal: 2.607 ± 0.539
0.186PheTrp: 0.186 ± 0.275
1.489PheTyr: 1.489 ± 0.487
0.0PheXaa: 0.0 ± 0.0
Gly
4.096GlyAla: 4.096 ± 0.652
2.979GlyCys: 2.979 ± 1.011
4.282GlyAsp: 4.282 ± 1.547
3.91GlyGlu: 3.91 ± 0.692
3.165GlyPhe: 3.165 ± 0.6
7.261GlyGly: 7.261 ± 1.802
0.745GlyHis: 0.745 ± 0.41
2.979GlyIle: 2.979 ± 0.462
2.607GlyLys: 2.607 ± 0.675
5.586GlyLeu: 5.586 ± 1.465
0.372GlyMet: 0.372 ± 0.238
2.048GlyAsn: 2.048 ± 0.45
0.372GlyPro: 0.372 ± 0.377
0.931GlyGln: 0.931 ± 0.387
3.538GlyArg: 3.538 ± 1.251
3.91GlySer: 3.91 ± 0.513
2.793GlyThr: 2.793 ± 0.668
5.772GlyVal: 5.772 ± 0.554
0.372GlyTrp: 0.372 ± 0.205
1.862GlyTyr: 1.862 ± 0.769
0.0GlyXaa: 0.0 ± 0.0
His
1.117HisAla: 1.117 ± 0.359
1.117HisCys: 1.117 ± 0.412
0.931HisAsp: 0.931 ± 0.381
0.745HisGlu: 0.745 ± 0.41
1.862HisPhe: 1.862 ± 0.471
0.372HisGly: 0.372 ± 0.33
0.186HisHis: 0.186 ± 0.103
0.931HisIle: 0.931 ± 0.313
1.117HisLys: 1.117 ± 0.328
1.862HisLeu: 1.862 ± 0.318
0.931HisMet: 0.931 ± 0.609
1.303HisAsn: 1.303 ± 0.449
0.372HisPro: 0.372 ± 0.205
0.745HisGln: 0.745 ± 0.31
1.862HisArg: 1.862 ± 0.71
2.234HisSer: 2.234 ± 0.987
1.862HisThr: 1.862 ± 0.813
0.745HisVal: 0.745 ± 0.286
0.0HisTrp: 0.0 ± 0.0
0.931HisTyr: 0.931 ± 0.331
0.0HisXaa: 0.0 ± 0.0
Ile
3.351IleAla: 3.351 ± 0.871
0.745IleCys: 0.745 ± 0.41
3.724IleAsp: 3.724 ± 1.139
4.282IleGlu: 4.282 ± 1.837
2.42IlePhe: 2.42 ± 0.559
2.42IleGly: 2.42 ± 0.71
1.489IleHis: 1.489 ± 0.474
2.793IleIle: 2.793 ± 0.704
4.096IleLys: 4.096 ± 0.977
3.538IleLeu: 3.538 ± 0.74
0.559IleMet: 0.559 ± 0.308
2.607IleAsn: 2.607 ± 1.731
2.793IlePro: 2.793 ± 0.686
0.372IleGln: 0.372 ± 0.233
2.048IleArg: 2.048 ± 0.44
6.889IleSer: 6.889 ± 1.17
4.096IleThr: 4.096 ± 1.529
4.096IleVal: 4.096 ± 0.588
0.372IleTrp: 0.372 ± 0.238
1.489IleTyr: 1.489 ± 0.544
0.0IleXaa: 0.0 ± 0.0
Lys
4.841LysAla: 4.841 ± 1.084
1.303LysCys: 1.303 ± 0.483
2.607LysAsp: 2.607 ± 0.84
3.538LysGlu: 3.538 ± 1.69
4.655LysPhe: 4.655 ± 1.101
3.538LysGly: 3.538 ± 0.697
1.303LysHis: 1.303 ± 0.295
3.538LysIle: 3.538 ± 1.096
2.42LysLys: 2.42 ± 1.012
5.399LysLeu: 5.399 ± 0.861
1.117LysMet: 1.117 ± 0.237
3.724LysAsn: 3.724 ± 0.584
2.607LysPro: 2.607 ± 0.645
2.42LysGln: 2.42 ± 0.389
4.282LysArg: 4.282 ± 1.428
7.075LysSer: 7.075 ± 1.049
2.048LysThr: 2.048 ± 0.443
5.213LysVal: 5.213 ± 1.189
0.186LysTrp: 0.186 ± 0.283
2.234LysTyr: 2.234 ± 0.645
0.0LysXaa: 0.0 ± 0.0
Leu
4.468LeuAla: 4.468 ± 0.558
2.42LeuCys: 2.42 ± 1.064
3.724LeuAsp: 3.724 ± 0.945
4.468LeuGlu: 4.468 ± 0.997
5.586LeuPhe: 5.586 ± 1.203
4.841LeuGly: 4.841 ± 1.682
2.234LeuHis: 2.234 ± 0.442
6.144LeuIle: 6.144 ± 0.536
7.261LeuLys: 7.261 ± 0.963
9.868LeuLeu: 9.868 ± 1.699
2.607LeuMet: 2.607 ± 0.745
5.586LeuAsn: 5.586 ± 1.743
3.351LeuPro: 3.351 ± 0.609
2.979LeuGln: 2.979 ± 1.253
6.703LeuArg: 6.703 ± 0.949
9.309LeuSer: 9.309 ± 0.842
4.468LeuThr: 4.468 ± 0.775
8.565LeuVal: 8.565 ± 1.15
0.186LeuTrp: 0.186 ± 0.439
3.351LeuTyr: 3.351 ± 0.978
0.0LeuXaa: 0.0 ± 0.0
Met
2.42MetAla: 2.42 ± 0.543
0.186MetCys: 0.186 ± 0.372
0.931MetAsp: 0.931 ± 0.965
0.745MetGlu: 0.745 ± 0.477
0.372MetPhe: 0.372 ± 0.238
0.559MetGly: 0.559 ± 0.243
0.372MetHis: 0.372 ± 0.205
0.186MetIle: 0.186 ± 0.339
1.676MetLys: 1.676 ± 0.716
1.303MetLeu: 1.303 ± 0.8
0.745MetMet: 0.745 ± 0.265
1.303MetAsn: 1.303 ± 0.704
0.559MetPro: 0.559 ± 0.836
1.303MetGln: 1.303 ± 0.58
0.931MetArg: 0.931 ± 0.382
1.489MetSer: 1.489 ± 0.413
0.559MetThr: 0.559 ± 0.243
2.42MetVal: 2.42 ± 0.449
0.0MetTrp: 0.0 ± 0.0
0.372MetTyr: 0.372 ± 0.205
0.0MetXaa: 0.0 ± 0.0
Asn
2.979AsnAla: 2.979 ± 1.005
0.186AsnCys: 0.186 ± 0.439
2.793AsnAsp: 2.793 ± 1.071
3.91AsnGlu: 3.91 ± 1.337
2.048AsnPhe: 2.048 ± 0.912
3.165AsnGly: 3.165 ± 1.348
1.117AsnHis: 1.117 ± 0.359
2.979AsnIle: 2.979 ± 0.481
2.607AsnLys: 2.607 ± 1.201
3.91AsnLeu: 3.91 ± 0.999
1.117AsnMet: 1.117 ± 0.596
2.234AsnAsn: 2.234 ± 0.752
1.489AsnPro: 1.489 ± 0.709
0.931AsnGln: 0.931 ± 0.398
2.607AsnArg: 2.607 ± 1.146
4.841AsnSer: 4.841 ± 0.871
3.538AsnThr: 3.538 ± 0.967
2.793AsnVal: 2.793 ± 1.365
0.186AsnTrp: 0.186 ± 0.275
0.931AsnTyr: 0.931 ± 0.513
0.0AsnXaa: 0.0 ± 0.0
Pro
1.303ProAla: 1.303 ± 0.468
0.372ProCys: 0.372 ± 0.205
2.048ProAsp: 2.048 ± 0.67
2.234ProGlu: 2.234 ± 0.648
2.607ProPhe: 2.607 ± 0.508
2.048ProGly: 2.048 ± 0.666
1.303ProHis: 1.303 ± 0.483
1.676ProIle: 1.676 ± 0.597
2.607ProLys: 2.607 ± 0.889
2.607ProLeu: 2.607 ± 0.806
0.559ProMet: 0.559 ± 0.461
1.303ProAsn: 1.303 ± 0.787
1.303ProPro: 1.303 ± 0.43
0.745ProGln: 0.745 ± 0.502
2.234ProArg: 2.234 ± 0.449
2.607ProSer: 2.607 ± 0.945
2.048ProThr: 2.048 ± 0.647
1.303ProVal: 1.303 ± 0.667
0.186ProTrp: 0.186 ± 0.103
1.676ProTyr: 1.676 ± 0.533
0.0ProXaa: 0.0 ± 0.0
Gln
0.745GlnAla: 0.745 ± 0.41
0.559GlnCys: 0.559 ± 0.308
0.745GlnAsp: 0.745 ± 0.286
2.607GlnGlu: 2.607 ± 0.815
0.559GlnPhe: 0.559 ± 0.243
0.745GlnGly: 0.745 ± 0.466
1.117GlnHis: 1.117 ± 0.575
1.862GlnIle: 1.862 ± 0.454
1.303GlnLys: 1.303 ± 0.502
3.351GlnLeu: 3.351 ± 0.892
0.372GlnMet: 0.372 ± 0.205
1.489GlnAsn: 1.489 ± 0.401
0.745GlnPro: 0.745 ± 1.102
0.559GlnGln: 0.559 ± 0.227
1.862GlnArg: 1.862 ± 0.554
1.676GlnSer: 1.676 ± 0.454
2.234GlnThr: 2.234 ± 0.404
0.931GlnVal: 0.931 ± 0.436
0.0GlnTrp: 0.0 ± 0.0
1.117GlnTyr: 1.117 ± 0.649
0.0GlnXaa: 0.0 ± 0.0
Arg
2.42ArgAla: 2.42 ± 1.043
3.165ArgCys: 3.165 ± 0.843
3.91ArgAsp: 3.91 ± 1.785
2.607ArgGlu: 2.607 ± 0.674
2.607ArgPhe: 2.607 ± 0.945
3.724ArgGly: 3.724 ± 0.957
0.931ArgHis: 0.931 ± 0.384
2.607ArgIle: 2.607 ± 0.918
4.655ArgLys: 4.655 ± 0.884
6.144ArgLeu: 6.144 ± 0.899
1.303ArgMet: 1.303 ± 0.587
3.165ArgAsn: 3.165 ± 1.062
2.048ArgPro: 2.048 ± 0.59
1.117ArgGln: 1.117 ± 0.615
4.282ArgArg: 4.282 ± 0.925
5.586ArgSer: 5.586 ± 1.467
2.607ArgThr: 2.607 ± 0.598
5.586ArgVal: 5.586 ± 0.961
0.559ArgTrp: 0.559 ± 0.599
0.931ArgTyr: 0.931 ± 0.284
0.0ArgXaa: 0.0 ± 0.0
Ser
4.841SerAla: 4.841 ± 0.879
2.048SerCys: 2.048 ± 0.927
7.075SerAsp: 7.075 ± 1.144
5.027SerGlu: 5.027 ± 0.972
4.282SerPhe: 4.282 ± 1.231
5.772SerGly: 5.772 ± 1.16
1.676SerHis: 1.676 ± 0.716
4.655SerIle: 4.655 ± 0.747
8.192SerLys: 8.192 ± 1.881
10.054SerLeu: 10.054 ± 1.213
0.931SerMet: 0.931 ± 0.352
3.351SerAsn: 3.351 ± 1.368
2.979SerPro: 2.979 ± 0.78
3.165SerGln: 3.165 ± 0.67
5.399SerArg: 5.399 ± 1.428
7.634SerSer: 7.634 ± 1.699
3.724SerThr: 3.724 ± 0.948
5.958SerVal: 5.958 ± 1.022
1.303SerTrp: 1.303 ± 0.965
3.351SerTyr: 3.351 ± 0.711
0.0SerXaa: 0.0 ± 0.0
Thr
2.793ThrAla: 2.793 ± 0.804
0.931ThrCys: 0.931 ± 0.215
2.42ThrAsp: 2.42 ± 0.634
3.351ThrGlu: 3.351 ± 0.616
2.979ThrPhe: 2.979 ± 1.492
3.538ThrGly: 3.538 ± 0.778
1.489ThrHis: 1.489 ± 0.595
3.165ThrIle: 3.165 ± 0.841
1.117ThrLys: 1.117 ± 0.359
7.075ThrLeu: 7.075 ± 1.025
0.559ThrMet: 0.559 ± 0.446
2.42ThrAsn: 2.42 ± 1.154
2.048ThrPro: 2.048 ± 0.504
1.862ThrGln: 1.862 ± 0.681
3.538ThrArg: 3.538 ± 1.155
4.655ThrSer: 4.655 ± 0.746
4.655ThrThr: 4.655 ± 0.848
2.979ThrVal: 2.979 ± 1.254
0.745ThrTrp: 0.745 ± 0.286
1.676ThrTyr: 1.676 ± 0.556
0.0ThrXaa: 0.0 ± 0.0
Val
4.468ValAla: 4.468 ± 0.891
1.862ValCys: 1.862 ± 0.707
4.841ValAsp: 4.841 ± 0.865
3.538ValGlu: 3.538 ± 1.079
3.351ValPhe: 3.351 ± 0.777
5.399ValGly: 5.399 ± 0.762
2.234ValHis: 2.234 ± 0.352
4.841ValIle: 4.841 ± 1.279
5.586ValLys: 5.586 ± 1.188
6.33ValLeu: 6.33 ± 0.733
0.559ValMet: 0.559 ± 0.243
4.282ValAsn: 4.282 ± 0.79
2.048ValPro: 2.048 ± 0.65
1.862ValGln: 1.862 ± 0.467
4.841ValArg: 4.841 ± 0.958
6.516ValSer: 6.516 ± 1.308
5.027ValThr: 5.027 ± 1.334
4.841ValVal: 4.841 ± 1.113
0.745ValTrp: 0.745 ± 0.41
2.42ValTyr: 2.42 ± 0.789
0.0ValXaa: 0.0 ± 0.0
Trp
0.559TrpAla: 0.559 ± 0.941
0.0TrpCys: 0.0 ± 0.0
0.372TrpAsp: 0.372 ± 0.33
0.372TrpGlu: 0.372 ± 0.238
0.372TrpPhe: 0.372 ± 0.205
0.745TrpGly: 0.745 ± 0.553
0.186TrpHis: 0.186 ± 0.103
0.559TrpIle: 0.559 ± 0.505
0.0TrpLys: 0.0 ± 0.0
1.117TrpLeu: 1.117 ± 0.447
0.186TrpMet: 0.186 ± 0.103
0.559TrpAsn: 0.559 ± 0.505
0.0TrpPro: 0.0 ± 0.0
0.0TrpGln: 0.0 ± 0.0
0.372TrpArg: 0.372 ± 0.33
0.0TrpSer: 0.0 ± 0.0
0.0TrpThr: 0.0 ± 0.0
0.745TrpVal: 0.745 ± 0.265
0.0TrpTrp: 0.0 ± 0.0
0.372TrpTyr: 0.372 ± 0.205
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.048TyrAla: 2.048 ± 0.385
0.931TyrCys: 0.931 ± 0.513
1.862TyrAsp: 1.862 ± 0.707
2.048TyrGlu: 2.048 ± 0.493
1.489TyrPhe: 1.489 ± 0.401
1.489TyrGly: 1.489 ± 0.92
0.559TyrHis: 0.559 ± 0.446
2.234TyrIle: 2.234 ± 0.583
1.676TyrLys: 1.676 ± 0.599
4.841TyrLeu: 4.841 ± 0.55
0.372TyrMet: 0.372 ± 0.402
1.489TyrAsn: 1.489 ± 0.585
0.559TyrPro: 0.559 ± 0.308
0.745TyrGln: 0.745 ± 0.41
0.931TyrArg: 0.931 ± 0.397
2.607TyrSer: 2.607 ± 0.733
2.234TyrThr: 2.234 ± 0.877
3.351TyrVal: 3.351 ± 0.698
0.559TyrTrp: 0.559 ± 0.431
2.048TyrTyr: 2.048 ± 0.844
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 9 proteins (5372 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski