Amino acid dipepetide frequency for Wuhan insect virus 28

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
6.941AlaAla: 6.941 ± 0.551
0.992AlaCys: 0.992 ± 0.73
3.966AlaAsp: 3.966 ± 0.798
4.462AlaGlu: 4.462 ± 0.253
3.966AlaPhe: 3.966 ± 1.505
5.454AlaGly: 5.454 ± 0.23
0.992AlaHis: 0.992 ± 0.022
4.462AlaIle: 4.462 ± 1.163
1.487AlaLys: 1.487 ± 1.095
8.428AlaLeu: 8.428 ± 1.96
2.479AlaMet: 2.479 ± 0.298
5.454AlaAsn: 5.454 ± 0.23
2.975AlaPro: 2.975 ± 1.348
2.975AlaGln: 2.975 ± 0.067
5.454AlaArg: 5.454 ± 0.938
7.437AlaSer: 7.437 ± 0.522
3.966AlaThr: 3.966 ± 1.505
3.966AlaVal: 3.966 ± 0.09
2.975AlaTrp: 2.975 ± 1.348
2.479AlaTyr: 2.479 ± 0.41
0.0AlaXaa: 0.0 ± 0.0
Cys
1.487CysAla: 1.487 ± 0.388
0.992CysCys: 0.992 ± 0.73
0.992CysAsp: 0.992 ± 0.73
0.496CysGlu: 0.496 ± 0.365
0.0CysPhe: 0.0 ± 0.0
1.487CysGly: 1.487 ± 0.32
0.0CysHis: 0.0 ± 0.0
0.0CysIle: 0.0 ± 0.0
0.0CysLys: 0.0 ± 0.0
0.992CysLeu: 0.992 ± 0.73
1.487CysMet: 1.487 ± 0.32
0.0CysAsn: 0.0 ± 0.0
0.496CysPro: 0.496 ± 0.343
0.0CysGln: 0.0 ± 0.0
0.496CysArg: 0.496 ± 0.365
0.0CysSer: 0.0 ± 0.0
0.992CysThr: 0.992 ± 0.022
1.983CysVal: 1.983 ± 0.753
0.992CysTrp: 0.992 ± 0.022
0.0CysTyr: 0.0 ± 0.0
0.0CysXaa: 0.0 ± 0.0
Asp
6.445AspAla: 6.445 ± 1.915
0.992AspCys: 0.992 ± 0.022
6.445AspAsp: 6.445 ± 0.5
3.471AspGlu: 3.471 ± 0.983
0.496AspPhe: 0.496 ± 0.343
3.471AspGly: 3.471 ± 0.983
0.992AspHis: 0.992 ± 0.685
3.966AspIle: 3.966 ± 0.618
4.462AspLys: 4.462 ± 0.253
5.949AspLeu: 5.949 ± 0.135
1.983AspMet: 1.983 ± 0.045
2.479AspAsn: 2.479 ± 0.298
0.496AspPro: 0.496 ± 0.365
1.983AspGln: 1.983 ± 0.753
3.471AspArg: 3.471 ± 0.983
2.479AspSer: 2.479 ± 1.713
2.975AspThr: 2.975 ± 0.775
6.445AspVal: 6.445 ± 0.5
0.992AspTrp: 0.992 ± 0.022
1.983AspTyr: 1.983 ± 0.045
0.496AspXaa: 0.496 ± 0.365
Glu
4.462GluAla: 4.462 ± 0.253
0.496GluCys: 0.496 ± 0.343
4.958GluAsp: 4.958 ± 0.112
1.983GluGlu: 1.983 ± 0.045
2.975GluPhe: 2.975 ± 0.64
5.454GluGly: 5.454 ± 0.23
0.496GluHis: 0.496 ± 0.343
1.983GluIle: 1.983 ± 0.045
4.462GluLys: 4.462 ± 1.87
2.975GluLeu: 2.975 ± 1.348
0.992GluMet: 0.992 ± 0.022
2.975GluAsn: 2.975 ± 1.483
1.983GluPro: 1.983 ± 0.663
2.479GluGln: 2.479 ± 0.298
2.975GluArg: 2.975 ± 0.067
1.487GluSer: 1.487 ± 0.32
3.471GluThr: 3.471 ± 0.432
6.445GluVal: 6.445 ± 0.5
1.487GluTrp: 1.487 ± 1.095
0.992GluTyr: 0.992 ± 0.73
0.0GluXaa: 0.0 ± 0.0
Phe
0.496PheAla: 0.496 ± 0.343
0.496PheCys: 0.496 ± 0.365
2.479PheAsp: 2.479 ± 1.005
4.462PheGlu: 4.462 ± 0.253
0.992PhePhe: 0.992 ± 0.685
4.462PheGly: 4.462 ± 1.163
0.0PheHis: 0.0 ± 0.0
0.496PheIle: 0.496 ± 0.365
0.992PheLys: 0.992 ± 0.685
2.479PheLeu: 2.479 ± 1.118
0.992PheMet: 0.992 ± 0.73
0.992PheAsn: 0.992 ± 0.73
0.0PhePro: 0.0 ± 0.0
1.487PheGln: 1.487 ± 0.32
0.992PheArg: 0.992 ± 0.685
2.975PheSer: 2.975 ± 0.067
1.983PheThr: 1.983 ± 1.371
1.487PheVal: 1.487 ± 0.32
0.0PheTrp: 0.0 ± 0.0
0.496PheTyr: 0.496 ± 0.365
0.0PheXaa: 0.0 ± 0.0
Gly
7.437GlyAla: 7.437 ± 0.893
0.992GlyCys: 0.992 ± 0.022
3.471GlyAsp: 3.471 ± 1.14
2.975GlyGlu: 2.975 ± 0.067
3.471GlyPhe: 3.471 ± 0.983
6.445GlyGly: 6.445 ± 0.5
1.983GlyHis: 1.983 ± 0.045
2.479GlyIle: 2.479 ± 0.298
2.479GlyLys: 2.479 ± 0.41
8.924GlyLeu: 8.924 ± 0.91
3.471GlyMet: 3.471 ± 0.275
6.445GlyAsn: 6.445 ± 2.331
3.471GlyPro: 3.471 ± 1.691
1.983GlyGln: 1.983 ± 0.045
5.454GlyArg: 5.454 ± 0.477
3.966GlySer: 3.966 ± 0.09
4.958GlyThr: 4.958 ± 0.82
5.454GlyVal: 5.454 ± 1.646
1.983GlyTrp: 1.983 ± 0.753
1.983GlyTyr: 1.983 ± 0.753
0.0GlyXaa: 0.0 ± 0.0
His
0.992HisAla: 0.992 ± 0.73
0.0HisCys: 0.0 ± 0.0
0.0HisAsp: 0.0 ± 0.0
1.983HisGlu: 1.983 ± 0.663
0.992HisPhe: 0.992 ± 0.022
0.992HisGly: 0.992 ± 0.73
0.496HisHis: 0.496 ± 0.343
0.0HisIle: 0.0 ± 0.0
1.983HisLys: 1.983 ± 0.045
2.479HisLeu: 2.479 ± 1.118
0.992HisMet: 0.992 ± 0.022
0.992HisAsn: 0.992 ± 0.022
0.992HisPro: 0.992 ± 0.73
0.496HisGln: 0.496 ± 0.343
0.0HisArg: 0.0 ± 0.0
0.496HisSer: 0.496 ± 0.343
0.992HisThr: 0.992 ± 0.022
2.975HisVal: 2.975 ± 1.348
0.0HisTrp: 0.0 ± 0.0
0.496HisTyr: 0.496 ± 0.365
0.0HisXaa: 0.0 ± 0.0
Ile
2.975IleAla: 2.975 ± 0.775
1.487IleCys: 1.487 ± 1.095
0.992IleAsp: 0.992 ± 0.022
2.975IleGlu: 2.975 ± 0.067
0.992IlePhe: 0.992 ± 0.022
2.479IleGly: 2.479 ± 1.005
0.992IleHis: 0.992 ± 0.022
0.992IleIle: 0.992 ± 0.685
4.958IleLys: 4.958 ± 0.82
1.487IleLeu: 1.487 ± 0.32
2.479IleMet: 2.479 ± 0.41
2.975IleAsn: 2.975 ± 1.348
2.479IlePro: 2.479 ± 1.005
0.992IleGln: 0.992 ± 0.022
1.983IleArg: 1.983 ± 0.663
3.471IleSer: 3.471 ± 1.14
1.487IleThr: 1.487 ± 0.388
0.496IleVal: 0.496 ± 0.365
0.992IleTrp: 0.992 ± 0.73
0.992IleTyr: 0.992 ± 0.685
0.496IleXaa: 0.496 ± 0.343
Lys
5.454LysAla: 5.454 ± 1.893
0.0LysCys: 0.0 ± 0.0
1.487LysAsp: 1.487 ± 0.32
3.471LysGlu: 3.471 ± 1.14
0.992LysPhe: 0.992 ± 0.022
4.462LysGly: 4.462 ± 0.455
0.992LysHis: 0.992 ± 0.685
2.479LysIle: 2.479 ± 0.41
4.462LysLys: 4.462 ± 0.961
2.975LysLeu: 2.975 ± 0.067
2.975LysMet: 2.975 ± 0.64
2.975LysAsn: 2.975 ± 0.64
3.471LysPro: 3.471 ± 1.691
1.487LysGln: 1.487 ± 0.388
3.471LysArg: 3.471 ± 1.14
4.462LysSer: 4.462 ± 0.253
4.958LysThr: 4.958 ± 0.82
5.454LysVal: 5.454 ± 1.893
1.487LysTrp: 1.487 ± 0.388
0.992LysTyr: 0.992 ± 0.685
0.0LysXaa: 0.0 ± 0.0
Leu
8.924LeuAla: 8.924 ± 0.202
1.487LeuCys: 1.487 ± 1.028
5.454LeuAsp: 5.454 ± 0.938
3.966LeuGlu: 3.966 ± 1.505
0.496LeuPhe: 0.496 ± 0.343
5.949LeuGly: 5.949 ± 1.281
1.487LeuHis: 1.487 ± 0.388
2.479LeuIle: 2.479 ± 1.118
5.949LeuLys: 5.949 ± 1.55
7.437LeuLeu: 7.437 ± 0.522
2.975LeuMet: 2.975 ± 0.775
4.958LeuAsn: 4.958 ± 0.112
6.445LeuPro: 6.445 ± 0.208
3.966LeuGln: 3.966 ± 0.798
6.445LeuArg: 6.445 ± 3.331
5.454LeuSer: 5.454 ± 1.185
3.966LeuThr: 3.966 ± 0.09
3.471LeuVal: 3.471 ± 0.432
1.983LeuTrp: 1.983 ± 1.371
2.975LeuTyr: 2.975 ± 0.64
0.496LeuXaa: 0.496 ± 0.343
Met
1.487MetAla: 1.487 ± 0.388
0.0MetCys: 0.0 ± 0.0
1.983MetAsp: 1.983 ± 0.045
1.487MetGlu: 1.487 ± 0.388
0.992MetPhe: 0.992 ± 0.685
3.966MetGly: 3.966 ± 0.618
0.496MetHis: 0.496 ± 0.365
0.496MetIle: 0.496 ± 0.365
1.487MetLys: 1.487 ± 0.388
1.983MetLeu: 1.983 ± 0.753
1.487MetMet: 1.487 ± 0.388
2.479MetAsn: 2.479 ± 1.005
2.975MetPro: 2.975 ± 1.348
0.992MetGln: 0.992 ± 0.73
2.975MetArg: 2.975 ± 0.64
5.454MetSer: 5.454 ± 0.23
2.975MetThr: 2.975 ± 0.64
2.975MetVal: 2.975 ± 0.067
1.983MetTrp: 1.983 ± 0.045
1.983MetTyr: 1.983 ± 1.371
0.0MetXaa: 0.0 ± 0.0
Asn
4.462AsnAla: 4.462 ± 0.253
0.992AsnCys: 0.992 ± 0.022
5.454AsnAsp: 5.454 ± 2.354
1.983AsnGlu: 1.983 ± 0.663
1.983AsnPhe: 1.983 ± 0.753
5.949AsnGly: 5.949 ± 0.573
1.983AsnHis: 1.983 ± 0.663
1.983AsnIle: 1.983 ± 0.663
3.471AsnLys: 3.471 ± 1.14
2.479AsnLeu: 2.479 ± 1.005
1.983AsnMet: 1.983 ± 0.521
4.958AsnAsn: 4.958 ± 0.595
1.983AsnPro: 1.983 ± 0.663
1.487AsnGln: 1.487 ± 0.32
3.966AsnArg: 3.966 ± 0.09
1.487AsnSer: 1.487 ± 0.388
3.471AsnThr: 3.471 ± 1.14
2.975AsnVal: 2.975 ± 0.067
1.983AsnTrp: 1.983 ± 0.045
2.479AsnTyr: 2.479 ± 0.298
0.0AsnXaa: 0.0 ± 0.0
Pro
3.471ProAla: 3.471 ± 1.691
0.0ProCys: 0.0 ± 0.0
2.975ProAsp: 2.975 ± 0.067
1.487ProGlu: 1.487 ± 1.028
0.992ProPhe: 0.992 ± 0.685
5.454ProGly: 5.454 ± 0.938
0.496ProHis: 0.496 ± 0.365
1.983ProIle: 1.983 ± 0.663
5.949ProLys: 5.949 ± 0.573
2.479ProLeu: 2.479 ± 1.005
1.983ProMet: 1.983 ± 1.371
3.471ProAsn: 3.471 ± 0.983
1.983ProPro: 1.983 ± 1.371
0.0ProGln: 0.0 ± 0.0
1.983ProArg: 1.983 ± 0.663
2.479ProSer: 2.479 ± 1.713
3.966ProThr: 3.966 ± 0.618
1.983ProVal: 1.983 ± 0.663
0.496ProTrp: 0.496 ± 0.343
1.487ProTyr: 1.487 ± 0.388
0.0ProXaa: 0.0 ± 0.0
Gln
2.975GlnAla: 2.975 ± 0.64
0.496GlnCys: 0.496 ± 0.365
1.487GlnAsp: 1.487 ± 1.095
2.975GlnGlu: 2.975 ± 0.64
0.0GlnPhe: 0.0 ± 0.0
1.487GlnGly: 1.487 ± 1.028
0.0GlnHis: 0.0 ± 0.0
2.479GlnIle: 2.479 ± 0.298
1.487GlnLys: 1.487 ± 0.32
3.471GlnLeu: 3.471 ± 0.432
0.496GlnMet: 0.496 ± 0.365
2.975GlnAsn: 2.975 ± 0.067
2.479GlnPro: 2.479 ± 0.298
1.487GlnGln: 1.487 ± 0.32
0.496GlnArg: 0.496 ± 0.343
0.496GlnSer: 0.496 ± 0.365
0.992GlnThr: 0.992 ± 0.685
1.487GlnVal: 1.487 ± 0.32
0.992GlnTrp: 0.992 ± 0.73
1.983GlnTyr: 1.983 ± 0.753
0.0GlnXaa: 0.0 ± 0.0
Arg
3.966ArgAla: 3.966 ± 0.618
0.496ArgCys: 0.496 ± 0.365
5.454ArgAsp: 5.454 ± 2.354
2.975ArgGlu: 2.975 ± 0.067
2.975ArgPhe: 2.975 ± 0.64
4.462ArgGly: 4.462 ± 0.455
1.487ArgHis: 1.487 ± 0.388
3.471ArgIle: 3.471 ± 0.275
1.487ArgLys: 1.487 ± 0.32
5.454ArgLeu: 5.454 ± 0.477
2.479ArgMet: 2.479 ± 1.312
0.992ArgAsn: 0.992 ± 0.022
1.487ArgPro: 1.487 ± 0.32
3.966ArgGln: 3.966 ± 0.09
2.479ArgArg: 2.479 ± 1.005
2.975ArgSer: 2.975 ± 0.775
1.983ArgThr: 1.983 ± 0.045
3.471ArgVal: 3.471 ± 1.848
1.983ArgTrp: 1.983 ± 0.045
3.471ArgTyr: 3.471 ± 0.275
0.0ArgXaa: 0.0 ± 0.0
Ser
6.941SerAla: 6.941 ± 1.573
0.496SerCys: 0.496 ± 0.365
4.462SerAsp: 4.462 ± 0.961
4.462SerGlu: 4.462 ± 0.455
1.487SerPhe: 1.487 ± 1.095
4.462SerGly: 4.462 ± 1.668
1.487SerHis: 1.487 ± 0.388
2.479SerIle: 2.479 ± 0.298
2.975SerLys: 2.975 ± 1.348
4.462SerLeu: 4.462 ± 0.253
1.487SerMet: 1.487 ± 1.028
3.966SerAsn: 3.966 ± 0.09
3.966SerPro: 3.966 ± 0.618
1.487SerGln: 1.487 ± 1.028
3.471SerArg: 3.471 ± 0.432
2.975SerSer: 2.975 ± 0.64
4.958SerThr: 4.958 ± 0.112
2.479SerVal: 2.479 ± 0.298
0.992SerTrp: 0.992 ± 0.022
2.479SerTyr: 2.479 ± 1.118
0.0SerXaa: 0.0 ± 0.0
Thr
3.966ThrAla: 3.966 ± 0.798
0.496ThrCys: 0.496 ± 0.343
1.983ThrAsp: 1.983 ± 0.753
3.471ThrGlu: 3.471 ± 0.275
1.487ThrPhe: 1.487 ± 0.388
4.462ThrGly: 4.462 ± 1.163
1.487ThrHis: 1.487 ± 0.388
2.479ThrIle: 2.479 ± 1.118
3.471ThrLys: 3.471 ± 1.14
6.941ThrLeu: 6.941 ± 0.865
1.487ThrMet: 1.487 ± 0.388
3.966ThrAsn: 3.966 ± 0.798
2.479ThrPro: 2.479 ± 1.713
0.496ThrGln: 0.496 ± 0.343
4.462ThrArg: 4.462 ± 0.253
2.975ThrSer: 2.975 ± 1.348
1.487ThrThr: 1.487 ± 0.388
4.958ThrVal: 4.958 ± 0.112
0.992ThrTrp: 0.992 ± 0.022
1.487ThrTyr: 1.487 ± 0.32
0.0ThrXaa: 0.0 ± 0.0
Val
3.471ValAla: 3.471 ± 0.432
0.496ValCys: 0.496 ± 0.365
5.949ValAsp: 5.949 ± 0.135
2.975ValGlu: 2.975 ± 0.775
1.983ValPhe: 1.983 ± 0.045
5.454ValGly: 5.454 ± 0.477
0.992ValHis: 0.992 ± 0.73
0.992ValIle: 0.992 ± 0.022
4.958ValLys: 4.958 ± 0.595
6.445ValLeu: 6.445 ± 1.208
3.471ValMet: 3.471 ± 0.983
3.471ValAsn: 3.471 ± 0.983
3.471ValPro: 3.471 ± 0.275
2.975ValGln: 2.975 ± 0.64
5.454ValArg: 5.454 ± 0.477
3.966ValSer: 3.966 ± 0.618
2.975ValThr: 2.975 ± 0.067
5.454ValVal: 5.454 ± 1.185
1.487ValTrp: 1.487 ± 1.095
0.992ValTyr: 0.992 ± 0.73
0.496ValXaa: 0.496 ± 0.343
Trp
1.487TrpAla: 1.487 ± 0.388
0.0TrpCys: 0.0 ± 0.0
0.496TrpAsp: 0.496 ± 0.365
0.496TrpGlu: 0.496 ± 0.365
0.992TrpPhe: 0.992 ± 0.73
1.983TrpGly: 1.983 ± 0.753
0.496TrpHis: 0.496 ± 0.365
2.479TrpIle: 2.479 ± 1.005
0.496TrpLys: 0.496 ± 0.343
4.462TrpLeu: 4.462 ± 0.455
1.983TrpMet: 1.983 ± 0.045
0.496TrpAsn: 0.496 ± 0.365
1.487TrpPro: 1.487 ± 1.028
0.0TrpGln: 0.0 ± 0.0
0.992TrpArg: 0.992 ± 0.022
3.471TrpSer: 3.471 ± 0.432
1.487TrpThr: 1.487 ± 0.388
0.496TrpVal: 0.496 ± 0.343
0.0TrpTrp: 0.0 ± 0.0
1.487TrpTyr: 1.487 ± 0.388
0.0TrpXaa: 0.0 ± 0.0
Tyr
3.471TyrAla: 3.471 ± 0.432
1.487TyrCys: 1.487 ± 0.388
1.983TyrAsp: 1.983 ± 0.753
2.975TyrGlu: 2.975 ± 1.483
0.0TyrPhe: 0.0 ± 0.0
1.487TyrGly: 1.487 ± 1.095
0.992TyrHis: 0.992 ± 0.022
0.992TyrIle: 0.992 ± 0.022
1.487TyrLys: 1.487 ± 0.32
4.462TyrLeu: 4.462 ± 0.961
2.479TyrMet: 2.479 ± 1.713
0.496TyrAsn: 0.496 ± 0.343
0.0TyrPro: 0.0 ± 0.0
0.0TyrGln: 0.0 ± 0.0
0.992TyrArg: 0.992 ± 0.022
2.975TyrSer: 2.975 ± 0.067
0.992TyrThr: 0.992 ± 0.022
2.479TyrVal: 2.479 ± 0.41
1.487TyrTrp: 1.487 ± 0.388
0.992TyrTyr: 0.992 ± 0.685
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.496XaaPhe: 0.496 ± 0.343
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.496XaaSer: 0.496 ± 0.343
0.0XaaThr: 0.0 ± 0.0
0.992XaaVal: 0.992 ± 0.022
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.496XaaXaa: 0.496 ± 0.343
Statistics based on 2 proteins (2018 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski