Amino acid dipepetide frequency for Aquabacterium olei

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	17.391AlaAla: 17.391 ± 0.241	1.346AlaCys: 1.346 ± 0.036	6.747AlaAsp: 6.747 ± 0.081	7.054AlaGlu: 7.054 ± 0.086	3.908AlaPhe: 3.908 ± 0.06	10.337AlaGly: 10.337 ± 0.104	3.121AlaHis: 3.121 ± 0.058	4.827AlaIle: 4.827 ± 0.095	3.162AlaLys: 3.162 ± 0.055	15.446AlaLeu: 15.446 ± 0.242	3.538AlaMet: 3.538 ± 0.062	2.571AlaAsn: 2.571 ± 0.059	6.503AlaPro: 6.503 ± 0.092	5.84AlaGln: 5.84 ± 0.134	10.161AlaArg: 10.161 ± 0.115	6.822AlaSer: 6.822 ± 0.081	6.41AlaThr: 6.41 ± 0.113	9.496AlaVal: 9.496 ± 0.096	2.234AlaTrp: 2.234 ± 0.047	2.363AlaTyr: 2.363 ± 0.048	0.0AlaXaa: 0.0 ± 0.0
Cys	1.131CysAla: 1.131 ± 0.031	0.109CysCys: 0.109 ± 0.008	0.491CysAsp: 0.491 ± 0.021	0.512CysGlu: 0.512 ± 0.02	0.276CysPhe: 0.276 ± 0.014	0.961CysGly: 0.961 ± 0.029	0.295CysHis: 0.295 ± 0.016	0.339CysIle: 0.339 ± 0.016	0.228CysLys: 0.228 ± 0.015	0.879CysLeu: 0.879 ± 0.025	0.19CysMet: 0.19 ± 0.014	0.217CysAsn: 0.217 ± 0.013	0.542CysPro: 0.542 ± 0.023	0.312CysGln: 0.312 ± 0.015	0.585CysArg: 0.585 ± 0.024	0.476CysSer: 0.476 ± 0.022	0.492CysThr: 0.492 ± 0.021	0.722CysVal: 0.722 ± 0.023	0.15CysTrp: 0.15 ± 0.01	0.169CysTyr: 0.169 ± 0.011	0.0CysXaa: 0.0 ± 0.0
Asp	7.224AspAla: 7.224 ± 0.085	0.396AspCys: 0.396 ± 0.02	2.841AspAsp: 2.841 ± 0.066	3.439AspGlu: 3.439 ± 0.057	1.87AspPhe: 1.87 ± 0.039	4.673AspGly: 4.673 ± 0.096	1.296AspHis: 1.296 ± 0.033	2.376AspIle: 2.376 ± 0.047	1.624AspLys: 1.624 ± 0.041	5.473AspLeu: 5.473 ± 0.076	1.164AspMet: 1.164 ± 0.031	1.169AspAsn: 1.169 ± 0.036	2.977AspPro: 2.977 ± 0.048	1.844AspGln: 1.844 ± 0.04	3.668AspArg: 3.668 ± 0.057	2.031AspSer: 2.031 ± 0.046	3.053AspThr: 3.053 ± 0.088	4.27AspVal: 4.27 ± 0.063	0.991AspTrp: 0.991 ± 0.027	1.18AspTyr: 1.18 ± 0.03	0.0AspXaa: 0.0 ± 0.0
Glu	7.692GluAla: 7.692 ± 0.085	0.348GluCys: 0.348 ± 0.017	2.319GluAsp: 2.319 ± 0.047	2.387GluGlu: 2.387 ± 0.055	1.478GluPhe: 1.478 ± 0.036	4.132GluGly: 4.132 ± 0.07	1.428GluHis: 1.428 ± 0.04	2.234GluIle: 2.234 ± 0.048	1.496GluLys: 1.496 ± 0.044	5.54GluLeu: 5.54 ± 0.082	1.109GluMet: 1.109 ± 0.027	0.979GluAsn: 0.979 ± 0.031	2.708GluPro: 2.708 ± 0.05	2.662GluGln: 2.662 ± 0.048	4.608GluArg: 4.608 ± 0.082	2.247GluSer: 2.247 ± 0.044	2.472GluThr: 2.472 ± 0.06	4.303GluVal: 4.303 ± 0.066	0.674GluTrp: 0.674 ± 0.023	0.839GluTyr: 0.839 ± 0.027	0.0GluXaa: 0.0 ± 0.0
Phe	3.685PheAla: 3.685 ± 0.056	0.335PheCys: 0.335 ± 0.017	2.353PheAsp: 2.353 ± 0.047	1.938PheGlu: 1.938 ± 0.04	1.228PhePhe: 1.228 ± 0.036	3.013PheGly: 3.013 ± 0.048	0.736PheHis: 0.736 ± 0.023	1.325PheIle: 1.325 ± 0.036	1.094PheLys: 1.094 ± 0.027	2.71PheLeu: 2.71 ± 0.051	0.825PheMet: 0.825 ± 0.024	1.026PheAsn: 1.026 ± 0.027	1.332PhePro: 1.332 ± 0.036	1.113PheGln: 1.113 ± 0.029	1.794PheArg: 1.794 ± 0.043	1.918PheSer: 1.918 ± 0.04	1.932PheThr: 1.932 ± 0.054	2.634PheVal: 2.634 ± 0.05	0.489PheTrp: 0.489 ± 0.023	0.792PheTyr: 0.792 ± 0.028	0.0PheXaa: 0.0 ± 0.0
Gly	9.053GlyAla: 9.053 ± 0.104	0.907GlyCys: 0.907 ± 0.031	3.947GlyAsp: 3.947 ± 0.053	4.432GlyGlu: 4.432 ± 0.073	3.101GlyPhe: 3.101 ± 0.048	6.843GlyGly: 6.843 ± 0.104	2.299GlyHis: 2.299 ± 0.049	3.394GlyIle: 3.394 ± 0.062	2.846GlyLys: 2.846 ± 0.058	9.642GlyLeu: 9.642 ± 0.093	2.291GlyMet: 2.291 ± 0.045	1.934GlyAsn: 1.934 ± 0.044	3.329GlyPro: 3.329 ± 0.053	3.841GlyGln: 3.841 ± 0.064	5.941GlyArg: 5.941 ± 0.083	4.325GlySer: 4.325 ± 0.077	4.695GlyThr: 4.695 ± 0.146	6.74GlyVal: 6.74 ± 0.085	1.617GlyTrp: 1.617 ± 0.042	1.995GlyTyr: 1.995 ± 0.047	0.0GlyXaa: 0.0 ± 0.0
His	3.379HisAla: 3.379 ± 0.065	0.263HisCys: 0.263 ± 0.016	1.408HisAsp: 1.408 ± 0.038	1.214HisGlu: 1.214 ± 0.032	0.904HisPhe: 0.904 ± 0.027	2.355HisGly: 2.355 ± 0.05	0.831HisHis: 0.831 ± 0.03	0.964HisIle: 0.964 ± 0.028	0.543HisLys: 0.543 ± 0.02	2.586HisLeu: 2.586 ± 0.051	0.487HisMet: 0.487 ± 0.018	0.493HisAsn: 0.493 ± 0.02	1.727HisPro: 1.727 ± 0.037	0.823HisGln: 0.823 ± 0.029	1.795HisArg: 1.795 ± 0.039	0.969HisSer: 0.969 ± 0.028	1.367HisThr: 1.367 ± 0.035	1.808HisVal: 1.808 ± 0.043	0.466HisTrp: 0.466 ± 0.02	0.548HisTyr: 0.548 ± 0.021	0.0HisXaa: 0.0 ± 0.0
Ile	4.975IleAla: 4.975 ± 0.085	0.313IleCys: 0.313 ± 0.017	2.945IleAsp: 2.945 ± 0.048	2.979IleGlu: 2.979 ± 0.065	0.964IlePhe: 0.964 ± 0.029	3.741IleGly: 3.741 ± 0.063	0.847IleHis: 0.847 ± 0.025	1.232IleIle: 1.232 ± 0.04	1.384IleLys: 1.384 ± 0.038	3.063IleLeu: 3.063 ± 0.057	0.722IleMet: 0.722 ± 0.025	1.265IleAsn: 1.265 ± 0.038	1.845IlePro: 1.845 ± 0.04	1.332IleGln: 1.332 ± 0.036	2.473IleArg: 2.473 ± 0.05	1.959IleSer: 1.959 ± 0.042	2.475IleThr: 2.475 ± 0.077	3.203IleVal: 3.203 ± 0.052	0.441IleTrp: 0.441 ± 0.022	0.733IleTyr: 0.733 ± 0.024	0.0IleXaa: 0.0 ± 0.0
Lys	4.041LysAla: 4.041 ± 0.064	0.162LysCys: 0.162 ± 0.012	1.527LysAsp: 1.527 ± 0.039	1.315LysGlu: 1.315 ± 0.042	0.748LysPhe: 0.748 ± 0.028	2.423LysGly: 2.423 ± 0.047	0.577LysHis: 0.577 ± 0.022	1.124LysIle: 1.124 ± 0.04	1.135LysLys: 1.135 ± 0.044	3.071LysLeu: 3.071 ± 0.058	0.646LysMet: 0.646 ± 0.023	0.722LysAsn: 0.722 ± 0.026	1.882LysPro: 1.882 ± 0.045	1.165LysGln: 1.165 ± 0.031	1.929LysArg: 1.929 ± 0.044	1.348LysSer: 1.348 ± 0.034	1.622LysThr: 1.622 ± 0.041	2.514LysVal: 2.514 ± 0.05	0.28LysTrp: 0.28 ± 0.015	0.553LysTyr: 0.553 ± 0.023	0.0LysXaa: 0.0 ± 0.0
Leu	14.704LeuAla: 14.704 ± 0.14	1.037LeuCys: 1.037 ± 0.025	6.155LeuAsp: 6.155 ± 0.071	4.718LeuGlu: 4.718 ± 0.072	3.281LeuPhe: 3.281 ± 0.061	8.864LeuGly: 8.864 ± 0.091	2.644LeuHis: 2.644 ± 0.059	4.242LeuIle: 4.242 ± 0.075	3.506LeuLys: 3.506 ± 0.06	10.802LeuLeu: 10.802 ± 0.137	2.709LeuMet: 2.709 ± 0.055	2.744LeuAsn: 2.744 ± 0.044	6.491LeuPro: 6.491 ± 0.09	4.451LeuGln: 4.451 ± 0.064	7.885LeuArg: 7.885 ± 0.106	6.857LeuSer: 6.857 ± 0.11	6.16LeuThr: 6.16 ± 0.104	7.972LeuVal: 7.972 ± 0.102	1.446LeuTrp: 1.446 ± 0.041	2.048LeuTyr: 2.048 ± 0.045	0.0LeuXaa: 0.0 ± 0.0
Met	3.32MetAla: 3.32 ± 0.055	0.161MetCys: 0.161 ± 0.011	1.162MetAsp: 1.162 ± 0.035	0.951MetGlu: 0.951 ± 0.029	0.588MetPhe: 0.588 ± 0.023	1.934MetGly: 1.934 ± 0.042	0.497MetHis: 0.497 ± 0.019	0.78MetIle: 0.78 ± 0.028	0.892MetLys: 0.892 ± 0.03	2.757MetLeu: 2.757 ± 0.049	0.57MetMet: 0.57 ± 0.02	0.707MetAsn: 0.707 ± 0.023	1.589MetPro: 1.589 ± 0.032	1.059MetGln: 1.059 ± 0.03	1.621MetArg: 1.621 ± 0.035	1.709MetSer: 1.709 ± 0.037	1.474MetThr: 1.474 ± 0.038	1.76MetVal: 1.76 ± 0.041	0.25MetTrp: 0.25 ± 0.014	0.333MetTyr: 0.333 ± 0.017	0.0MetXaa: 0.0 ± 0.0
Asn	2.923AsnAla: 2.923 ± 0.057	0.216AsnCys: 0.216 ± 0.012	1.27AsnAsp: 1.27 ± 0.04	1.218AsnGlu: 1.218 ± 0.036	0.754AsnPhe: 0.754 ± 0.026	2.057AsnGly: 2.057 ± 0.048	0.527AsnHis: 0.527 ± 0.023	0.938AsnIle: 0.938 ± 0.03	0.701AsnLys: 0.701 ± 0.028	2.498AsnLeu: 2.498 ± 0.043	0.527AsnMet: 0.527 ± 0.02	0.641AsnAsn: 0.641 ± 0.027	1.7AsnPro: 1.7 ± 0.057	0.893AsnGln: 0.893 ± 0.025	1.567AsnArg: 1.567 ± 0.035	0.997AsnSer: 0.997 ± 0.039	1.366AsnThr: 1.366 ± 0.047	1.82AsnVal: 1.82 ± 0.044	0.41AsnTrp: 0.41 ± 0.019	0.574AsnTyr: 0.574 ± 0.024	0.0AsnXaa: 0.0 ± 0.0
Pro	7.641ProAla: 7.641 ± 0.102	0.419ProCys: 0.419 ± 0.017	3.663ProAsp: 3.663 ± 0.062	3.44ProGlu: 3.44 ± 0.059	1.648ProPhe: 1.648 ± 0.038	4.85ProGly: 4.85 ± 0.071	1.321ProHis: 1.321 ± 0.032	1.816ProIle: 1.816 ± 0.045	1.371ProLys: 1.371 ± 0.04	5.439ProLeu: 5.439 ± 0.081	1.314ProMet: 1.314 ± 0.031	1.175ProAsn: 1.175 ± 0.033	2.961ProPro: 2.961 ± 0.063	2.082ProGln: 2.082 ± 0.045	3.307ProArg: 3.307 ± 0.065	2.892ProSer: 2.892 ± 0.064	2.946ProThr: 2.946 ± 0.068	4.82ProVal: 4.82 ± 0.066	0.886ProTrp: 0.886 ± 0.029	1.06ProTyr: 1.06 ± 0.029	0.0ProXaa: 0.0 ± 0.0
Gln	6.724GlnAla: 6.724 ± 0.1	0.301GlnCys: 0.301 ± 0.015	1.773GlnAsp: 1.773 ± 0.043	1.467GlnGlu: 1.467 ± 0.037	1.122GlnPhe: 1.122 ± 0.03	3.545GlnGly: 3.545 ± 0.063	1.071GlnHis: 1.071 ± 0.031	1.793GlnIle: 1.793 ± 0.079	1.0GlnLys: 1.0 ± 0.029	4.208GlnLeu: 4.208 ± 0.075	0.967GlnMet: 0.967 ± 0.031	0.717GlnAsn: 0.717 ± 0.021	2.61GlnPro: 2.61 ± 0.043	2.159GlnGln: 2.159 ± 0.045	3.624GlnArg: 3.624 ± 0.069	1.923GlnSer: 1.923 ± 0.042	2.17GlnThr: 2.17 ± 0.047	3.364GlnVal: 3.364 ± 0.115	0.697GlnTrp: 0.697 ± 0.026	0.758GlnTyr: 0.758 ± 0.025	0.0GlnXaa: 0.0 ± 0.0
Arg	8.273ArgAla: 8.273 ± 0.09	0.663ArgCys: 0.663 ± 0.027	3.762ArgAsp: 3.762 ± 0.064	4.045ArgGlu: 4.045 ± 0.063	2.803ArgPhe: 2.803 ± 0.046	4.702ArgGly: 4.702 ± 0.071	2.258ArgHis: 2.258 ± 0.046	3.146ArgIle: 3.146 ± 0.061	1.979ArgLys: 1.979 ± 0.046	8.72ArgLeu: 8.72 ± 0.115	1.874ArgMet: 1.874 ± 0.045	1.661ArgAsn: 1.661 ± 0.037	3.83ArgPro: 3.83 ± 0.061	3.475ArgGln: 3.475 ± 0.061	5.62ArgArg: 5.62 ± 0.092	3.309ArgSer: 3.309 ± 0.058	3.677ArgThr: 3.677 ± 0.055	5.683ArgVal: 5.683 ± 0.072	1.317ArgTrp: 1.317 ± 0.037	1.721ArgTyr: 1.721 ± 0.042	0.0ArgXaa: 0.0 ± 0.0
Ser	6.412SerAla: 6.412 ± 0.099	0.437SerCys: 0.437 ± 0.02	2.485SerAsp: 2.485 ± 0.048	2.399SerGlu: 2.399 ± 0.047	1.813SerPhe: 1.813 ± 0.044	4.968SerGly: 4.968 ± 0.088	1.212SerHis: 1.212 ± 0.036	1.93SerIle: 1.93 ± 0.049	1.324SerLys: 1.324 ± 0.035	5.832SerLeu: 5.832 ± 0.084	1.252SerMet: 1.252 ± 0.027	1.264SerAsn: 1.264 ± 0.051	3.032SerPro: 3.032 ± 0.056	2.015SerGln: 2.015 ± 0.048	3.545SerArg: 3.545 ± 0.059	2.951SerSer: 2.951 ± 0.078	3.123SerThr: 3.123 ± 0.095	4.047SerVal: 4.047 ± 0.063	0.802SerTrp: 0.802 ± 0.027	1.107SerTyr: 1.107 ± 0.032	0.0SerXaa: 0.0 ± 0.0
Thr	6.611ThrAla: 6.611 ± 0.159	0.422ThrCys: 0.422 ± 0.02	2.739ThrAsp: 2.739 ± 0.059	2.754ThrGlu: 2.754 ± 0.053	1.786ThrPhe: 1.786 ± 0.058	4.999ThrGly: 4.999 ± 0.107	1.236ThrHis: 1.236 ± 0.032	1.799ThrIle: 1.799 ± 0.06	1.142ThrLys: 1.142 ± 0.034	6.886ThrLeu: 6.886 ± 0.098	1.094ThrMet: 1.094 ± 0.032	1.184ThrAsn: 1.184 ± 0.042	3.938ThrPro: 3.938 ± 0.109	2.078ThrGln: 2.078 ± 0.066	3.608ThrArg: 3.608 ± 0.067	2.8ThrSer: 2.8 ± 0.086	3.057ThrThr: 3.057 ± 0.125	4.806ThrVal: 4.806 ± 0.119	0.851ThrTrp: 0.851 ± 0.025	1.065ThrTyr: 1.065 ± 0.035	0.0ThrXaa: 0.0 ± 0.0
Val	10.054ValAla: 10.054 ± 0.142	0.846ValCys: 0.846 ± 0.022	4.241ValAsp: 4.241 ± 0.068	3.841ValGlu: 3.841 ± 0.061	2.675ValPhe: 2.675 ± 0.053	5.846ValGly: 5.846 ± 0.071	1.866ValHis: 1.866 ± 0.039	3.339ValIle: 3.339 ± 0.062	2.381ValLys: 2.381 ± 0.056	8.685ValLeu: 8.685 ± 0.099	1.994ValMet: 1.994 ± 0.042	2.22ValAsn: 2.22 ± 0.061	4.201ValPro: 4.201 ± 0.067	3.127ValGln: 3.127 ± 0.051	5.68ValArg: 5.68 ± 0.082	4.597ValSer: 4.597 ± 0.073	4.344ValThr: 4.344 ± 0.104	6.739ValVal: 6.739 ± 0.099	1.203ValTrp: 1.203 ± 0.032	1.573ValTyr: 1.573 ± 0.04	0.0ValXaa: 0.0 ± 0.0
Trp	1.652TrpAla: 1.652 ± 0.041	0.179TrpCys: 0.179 ± 0.013	0.62TrpAsp: 0.62 ± 0.021	0.492TrpGlu: 0.492 ± 0.02	0.537TrpPhe: 0.537 ± 0.018	1.1TrpGly: 1.1 ± 0.034	0.451TrpHis: 0.451 ± 0.017	0.551TrpIle: 0.551 ± 0.024	0.384TrpLys: 0.384 ± 0.018	2.358TrpLeu: 2.358 ± 0.051	0.443TrpMet: 0.443 ± 0.016	0.342TrpAsn: 0.342 ± 0.018	0.883TrpPro: 0.883 ± 0.028	0.905TrpGln: 0.905 ± 0.034	1.581TrpArg: 1.581 ± 0.043	0.836TrpSer: 0.836 ± 0.025	0.768TrpThr: 0.768 ± 0.025	1.214TrpVal: 1.214 ± 0.033	0.379TrpTrp: 0.379 ± 0.02	0.293TrpTyr: 0.293 ± 0.016	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.395TyrAla: 2.395 ± 0.058	0.217TyrCys: 0.217 ± 0.013	1.111TyrAsp: 1.111 ± 0.028	1.063TyrGlu: 1.063 ± 0.031	0.788TyrPhe: 0.788 ± 0.027	1.831TyrGly: 1.831 ± 0.048	0.417TyrHis: 0.417 ± 0.019	0.743TyrIle: 0.743 ± 0.025	0.593TyrLys: 0.593 ± 0.023	2.124TyrLeu: 2.124 ± 0.039	0.398TyrMet: 0.398 ± 0.018	0.567TyrAsn: 0.567 ± 0.023	0.967TyrPro: 0.967 ± 0.029	0.818TyrGln: 0.818 ± 0.027	1.524TyrArg: 1.524 ± 0.034	0.981TyrSer: 0.981 ± 0.03	1.25TyrThr: 1.25 ± 0.039	1.536TyrVal: 1.536 ± 0.035	0.383TyrTrp: 0.383 ± 0.019	0.465TyrTyr: 0.465 ± 0.02	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 3665 proteins (1280499 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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